Works matching DE "INVESTIGATIONAL drugs"

Results: 2243

Drug Repurposing of New Treatments for Neuroendocrine Tumors.

Published in:

Cancers, 2025, v. 17, n. 15, p. 2488, doi. 10.3390/cancers17152488

By:

Bellino, Stefania;
Lucente, Daniela;
La Salvia, Anna

Publication type:

Article

Treatment of KRAS-Mutated Pancreatic Cancer: New Hope for the Patients?

Published in:

Cancers, 2025, v. 17, n. 15, p. 2453, doi. 10.3390/cancers17152453

By:

Krupa, Kamila;
Fudalej, Marta;
Włoszek, Emilia;
Miski, Hanna;
Badowska-Kozakiewicz, Anna M.;
Mękal, Dominika;
Budzik, Michał P.;
Czerw, Aleksandra;
Deptała, Andrzej

Publication type:

Article

Historical Perspective: Prostaglandin E<sub>1</sub>.

Published in:

Neonatology Today, 2025, v. 20, n. 7, p. 154

By:

Philips III, Joseph B.

Publication type:

Article

Investigational Oral IL-23 Receptor Antagonist Icotrokinra Improves Skin Clearance in Psoriasis in Phase 3 Study.

Published in:

Patient Care (Online), 2025, p. N.PAG

By:

Halsey, Grace

Publication type:

Article

A Paradigm Shift in Precision Medicine: Patient-Specific In Vivo Gene Editing for Rare Genetic Diseases.

Published in:

Indian Practitioner, 2025, v. 78, n. 7, p. 18

By:

Parmar, Utsav;
Sheth, Harsh

Publication type:

Article

Vertex VX-993 Misses Primary Endpoint in Mid-Stage Trial, Ending Investigation for Acute Pain.

Published in:

Patient Care (Online), 2025, p. N.PAG

By:

Halsey, Grace

Publication type:

Article

Multi-center phase II study of nab-paclitaxel plus camrelizumab versus nab-paclitaxel alone as second-line treatment for advanced gastric cancer.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf189

By:

Sun, Li;
Gong, Zhimin;
Wang, Lei;
Kuang, Li;
Huang, Qiao;
Pei, Bo;
Yuan, Xianglin;
Qiu, Hong

Publication type:

Article

Recaticimab: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1067, doi. 10.1007/s40265-025-02199-5

By:

Lamb, Yvette N.

Publication type:

Article

Tiratricol: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1059, doi. 10.1007/s40265-025-02197-7

By:

Lamb, Yvette N.

Publication type:

Article

Experiences with low-intervention clinical trials—the new category under the European Union Clinical Trials Regulation.

Published in:

Clinical Trials, 2025, v. 22, n. 4, p. 494, doi. 10.1177/17407745241309293

By:

de Jong, Amos J.;
Gardarsdottir, Helga;
Santa-Ana-Tellez, Yared;
de Boer, Anthonius;
Zuidgeest, Mira GP

Publication type:

Article

Social Value Communication Amidst the "Hype" of Psychedelic Research.

Published in:

American Journal of Bioethics, 2025, v. 25, n. 8, p. 107, doi. 10.1080/15265161.2025.2526744

By:

Propes, Caleigh;
Cheung, Katherine

Publication type:

Article

Dementia-slowing medication: latest developments.

Published in:

Nursing & Residential Care, 2018, v. 20, n. 9, p. 442, doi. 10.12968/nrec.2018.20.9.442

By:

Mendes, Aysha;
Palmer, Sarah

Publication type:

Article

Solanezumab trial results.

Published in:: Nursing & Residential Care, 2017, v. 19, n. 2, p. 67
Publication type:: Article

THREE-PARENT BABIES AND FDA JURISDICTION: THE CASE FOR REGULATING THREE-PARTY IN VITRO FERTILIZATION AS A DRUG AND BIOLOGIC.

Published in:

Creighton Law Review, 2020, v. 53, n. 2, p. 427

By:

Hamilton, Hallie A.

Publication type:

Article

Use of suboptimal control arms in randomized clinical trials of investigational cancer drugs in China, 2016–2021: An observational study.

Published in:

PLoS Medicine, 2023, v. 20, n. 12, p. 1, doi. 10.1371/journal.pmed.1004319

By:

Zhang, Yichen;
Chen, Dingyi;
Cheng, Siyuan;
Liang, Zhizhou;
Yang, Lu;
Li, Qian;
Bai, Lin;
Li, Huangqianyu;
Liu, Wei;
Shi, Luwen;
Guan, Xiaodong

Publication type:

Article

Towards intra-articular therapies for more than just symptom management in osteoarthritis.

Published in:

Drugs & Therapy Perspectives, 2023, v. 39, n. 11, p. 382, doi. 10.1007/s40267-023-01029-6

By:

Fung, Simon

Publication type:

Article

The need for new acutely acting antimigraine drugs: moving safely outside acute medication overuse.

Published in:

Journal of Headache & Pain, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s10194-019-1007-y

By:

van Hoogstraten, Willem Sebastiaan;
MaassenVanDenBrink, Antoinette

Publication type:

Article

Correction to: Therapeutic novelties in migraine: new drugs, new hope?

Published in:

Journal of Headache & Pain, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s10194-019-1013-0

By:

Do, Thien Phu;
Guo, Song;
Ashina, Messoud

Publication type:

Article

Therapeutic novelties in migraine: new drugs, new hope?

Published in:

Journal of Headache & Pain, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s10194-019-0974-3

By:

Do, Thien Phu;
Guo, Song;
Ashina, Messoud

Publication type:

Article

Regorafenib versus cabozantinb as second-line treatment after sorafenib for unresectable hepatocellular carcinoma: matching-adjusted indirect comparison analysis.

Published in:

Journal of Cancer Research & Clinical Oncology, 2021, v. 147, n. 12, p. 3665, doi. 10.1007/s00432-021-03602-w

By:

Casadei-Gardini, Andrea;
Rimassa, Lorenza;
Rimini, Margherita;
Yoo, Changhoon;
Ryoo, Baek-Yeol;
Lonardi, Sara;
Masi, Gianluca;
Kim, Hyung-Don;
Vivaldi, Caterina;
Ryu, Min-Hee;
Rizzato, Mario Domenico;
Salani, Francesca;
Bang, Yeonghak;
Pellino, Antonio;
Catanese, Silvia;
Burgio, Valentina;
Cascinu, Stefano;
Cucchetti, Alessandro

Publication type:

Article

Mutational profiling of lung adenocarcinoma in China detected by next-generation sequencing.

Published in:

Journal of Cancer Research & Clinical Oncology, 2020, v. 146, n. 9, p. 2277, doi. 10.1007/s00432-020-03284-w

By:

Zhou, Xiaoyun;
Xu, Xiaohui;
Tian, Zhenhuan;
Xu, Wang-Yang;
Cui, Yushang

Publication type:

Article

How Does Glycation Affect Binding Parameters of the Albumin-Gliclazide System in the Presence of Drugs Commonly Used in Diabetes? In Vitro Spectroscopic Study.

Published in:

Molecules, 2021, v. 26, n. 13, p. 3869, doi. 10.3390/molecules26133869

By:

Wiglusz, Katarzyna;
Żurawska-Płaksej, Ewa;
Rorbach-Dolata, Anna;
Piwowar, Agnieszka

Publication type:

Article

Clinical Trial Risk in Chronic Obstructive Pulmonary Disease: The Effects of Drug Class and Inclusion Criteria.

Published in:

Respiration, 2016, v. 91, n. 1, p. 79, doi. 10.1159/000442446

By:

Tam, Jeffrey T.Y.;
Parker, Jayson L.;
anastasopulos, Demetri;
Balter, Meyer S.

Publication type:

Article

New Developments in Inhaled Drugs: Within and Beyond the Lungs.

Published in:

Respiration, 2014, v. 88, n. 1, p. 1, doi. 10.1159/000362586

By:

Usmani, Omar S.

Publication type:

Article

An open-source high-content analysis workflow for CFTR function measurements using the forskolin-induced swelling assay.

Published in:

Bioinformatics, 2020, v. 36, n. 24, p. 5686, doi. 10.1093/bioinformatics/btaa1073

By:

Hagemeijer, Marne C;
Vonk, Annelotte M;
Awatade, Nikhil T;
Silva, Iris A L;
Tischer, Christian;
Hilsenstein, Volker;
Beekman, Jeffrey M;
Amaral, Margarida D;
Botelho, Hugo M

Publication type:

Article

Research in Integrative and Complementary Medicine: Particularities, Challenges, Obstacles, and Misunderstandings. Part 1: The Why and the How of Clinical Research.

Published in:

2025

By:

Cramer, Holger

Publication type:

Editorial

Antioxidants, Biological Markers, Catalase, Glutathione Peroxidase, Chronic Periodontitis, Saliva, Smokeless tobacco, Smoker.

Published in:

Frontiers in Health Informatics, 2024, v. 13, n. 8, p. 4999

By:

Recharla, Mahesh

Publication type:

Article

Preclinical and Clinical Investigations of Potential Drugs and Vaccines for COVID-19 Therapy: A Comprehensive Review With Recent Update.

Published in:

Clinical Pathology, 2024, p. 1, doi. 10.1177/2632010X241263054

By:

Mia, Md. Easin;
Howlader, Mithu;
Akter, Farzana;
Hossain, Md. Murad

Publication type:

Article

Inhibition of falcilysin from Plasmodium falciparum by interference with its closed-to-open dynamic transition.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06774-6

By:

Lin, Jianqing;
Yan, Xinfu;
Chung, Zara;
Liew, Chong Wai;
El Sahili, Abbas;
Pechnikova, Evgeniya V.;
Preiser, Peter R.;
Bozdech, Zbynek;
Gao, Yong-Gui;
Lescar, Julien

Publication type:

Article

Pyrimethamine reduced tumour growth in pre-clinical cancer models: a systematic review to identify potential pre-clinical studies for subsequent human clinical trials.

Published in:

Biology Methods & Protocols, 2024, v. 9, n. 1, p. 1, doi. 10.1093/biomethods/bpae021

By:

Manoharan, Sivananthan;
Ying, Lee Ying

Publication type:

Article

Different drug approaches to COVID-19 treatment worldwide: an update of new drugs and drugs repositioning to fight against the novel coronavirus.

Published in:

Therapeutic Advances in Vaccines & Immunotherapy, 2022, v. 10, p. 1, doi. 10.1177/25151355221144845

By:

Oliver, Josidel Conceição;
Silva, Evandro Neves;
Soares, Letícia Martins;
Scodeler, Gislaine Cristina;
Santos, Ana de Souza;
Corsetti, Patrícia Paiva;
Prudêncio, Carlos Roberto;
de Almeida, Leonardo Augusto

Publication type:

Article

DRUG UPDATE. Oncology Drug Reference Sheet: Sotorasib.

Published in:

ONS Voice, 2021, v. 36, n. 11, p. 23

By:

Weimer, Jaime

Publication type:

Article

New Radiopharmaceutical Improves Survival in Advanced Prostate Cancer.

Published in:

ONS Voice, 2021, v. 36, n. 11, p. 6

By:

Becze, Elisa

Publication type:

Article

Radioprotectant May Also Be a Radiobooster.

Published in:

ONS Voice, 2021, v. 36, n. 10, p. 14

By:

Becze, Elisa

Publication type:

Article

Targeted Therapy Drug Shows Promise in CLL.

Published in:

ONS Voice, 2021, v. 38, n. 5, p. 10

By:

Becze, Elisa

Publication type:

Article

What APRNs Need to Know About Right to Try.

Published in:

ONS Voice, 2018, v. 33, n. 10, p. 50

By:

Backler, Chelsea

Publication type:

Article

How the FDA Provides New Approaches to Old Problems.

Published in:

ONS Voice, 2017, v. 32, n. 11, p. 32

By:

Stone, Alec

Publication type:

Article

Protection for medication-induced hearing loss: the state of the science.

Published in:

International Journal of Audiology, 2018, v. 57, n. sup4, p. S67, doi. 10.1080/14992027.2018.1455114

By:

Hammill, Tanisha L.;
Campbell, Kathleen C.

Publication type:

Article

Protection for medication-induced hearing loss: the state of the science.

Published in:

International Journal of Audiology, 2018, v. 57, p. S87, doi. 10.1080/14992027.2018.1455114

By:

Hammill, Tanisha L.;
Campbell, Kathleen C.

Publication type:

Article

Promising Drugs Targeting Specific Mechanisms of Deregulation in T Cell Lineage Acute Lymphoblastic Leukemia.

Published in:

Oncology & Therapy, 2025, v. 13, n. 2, p. 325, doi. 10.1007/s40487-025-00339-1

By:

Thomas, Xavier

Publication type:

Article

Use of cancer-directed therapy at the end of life among adolescents and young adults.

Published in:

JNCI: Journal of the National Cancer Institute, 2024, v. 116, n. 7, p. 1080, doi. 10.1093/jnci/djae038

By:

Mack, Jennifer W;
Cernik, Colin;
Xu, Lanfang;
Laurent, Cecile A;
Fisher, Lauren;
Cannizzaro, Nancy;
Munneke, Julie;
Cooper, Robert M;
Lakin, Joshua R;
Schwartz, Corey M;
Casperson, Mallory;
Altschuler, Andrea;
Wiener, Lori;
Kushi, Lawrence H;
Chao, Chun R;
Uno, Hajime

Publication type:

Article

"I Think It's Been Met With a Shrug:" Oncologists' Views Toward and Experiences With Right-to-Try.

Published in:

2021

By:

Smith, Cambray;
Stout, Jeremiah;
Adjei, Alex A;
Buckner, Jan;
Wentworth, Mark;
Tilburt, Jon;
Master, Zubin

Publication type:

journal article

Proportion of Patients in Phase I Oncology Trials Receiving Treatments That Are Ultimately Approved.

Published in:

2020

By:

Zhang, Sean X;
Fergusson, Dean;
Kimmelman, Jonathan

Publication type:

journal article

Lack of Availability and Efficacy of Phase I and Basket Trials for Patients With Gastrointestinal Cancers.

Published in:

2020

By:

Agarwal, Rajiv;
Cangemi, Nicholas A;
Epstein, Andrew S;
Harding, James;
Reidy-Lagunes, Diane;
Saltz, Leonard B

Publication type:

journal article

A mechanistic approach to the use of topical therapy to treat neuropathic pain.

Published in:

Journal of the Peripheral Nervous System, 2014, v. 19, p. S10, doi. 10.1111/jns.12080_1

By:

Campbell, J

Publication type:

Article

Z944: A first in class T-type calcium channel modulator for the treatment of pain.

Published in:

Journal of the Peripheral Nervous System, 2014, v. 19, p. S11, doi. 10.1111/jns.12080_2

By:

Lee, M

Publication type:

Article

Development of EMA401 as an orally-administered, highly-selective angiotensin II type 2 receptor antagonist for the treatment of neuropathic pain.

Published in:

Journal of the Peripheral Nervous System, 2014, v. 19, p. S13, doi. 10.1111/jns.12080_4

By:

McCarthy, T

Publication type:

Article

Designing innovative therapies for neuropathic pain: preclinical and early clinical development challenges.

Published in:

Journal of the Peripheral Nervous System, 2014, v. 19, p. S28, doi. 10.1111/jns.12082

By:

Höke, A;
Simpson, DM;
Freeman, R

Publication type:

Article

How therapeutic advances have transformed the medical landscape: a primer for clinicians.

Published in:

Internal Medicine Journal, 2023, v. 53, n. 8, p. 1306, doi. 10.1111/imj.16142

By:

Ghinea, Narcyz;
Lipworth, Wendy;
Kerridge, Ian;
Zalcberg, John R.

Publication type:

Article

Putting the best foot forward when treating newly diagnosed multiple myeloma.

Published in:

Internal Medicine Journal, 2023, v. 53, n. 3, p. 318, doi. 10.1111/imj.16034

By:

Lim, Sueh‐li;
Spencer, Andrew

Publication type:

Article