Works matching DE "INTERLEUKIN-5"

Results: 494

Th2-High Severe Asthma with Hypereosinophilia in the Spectrum of Type 2 Inflammatory Diseases.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5342, doi. 10.3390/ijms26115342

By:

Malaya, Elizabeth;
Marszałek, Kamil;
Kuna, Piotr;
Kupczyk, Maciej;
Panek, Michał

Publication type:

Article

Persistent Eosinophilic Inflammation Is Not a Feature of Type 2 CRS Patients Failing Anti‐IL‐5R Therapy and Requiring Class Switching to Anti‐IL‐4/13.

Published in:

International Forum of Allergy & Rhinology, 2025, v. 15, n. 6, p. 602, doi. 10.1002/alr.23534

By:

Sacks, Peta‐Lee;
Meerwein, Christian M;
Earls, Peter;
Thiel, Cedric;
Choy, Christine;
Campbell, Raewyn G;
Sacks, Raymond;
Kalish, Larry;
Harvey, Richard J

Publication type:

Article

Real-world safety and effectiveness of mepolizumab for patients with eosinophilic granulomatosis with polyangiitis in Japan: Long-term observation of the MARS study.

Published in:

Modern Rheumatology, 2025, v. 35, n. 3, p. 505, doi. 10.1093/mr/roae100

By:

Ishii, Tomonori;
Kunishige, Hideaki;
Kobayashi, Tamami;
Hayashi, Etsuko;
Komatsubara, Masaki;
Alfonso-Cristancho, Rafael;
Tamaoki, Jun;
Howarth, Peter

Publication type:

Article

Komplexní role IL-5 v patogenezi eozinofilního astmatu.

Published in:

Studia Pneumologica et Phthiseologica, 2024, v. 84, n. 4, p. 109

By:

Novosad, J.;
Krčmová, I.

Publication type:

Article

B cell responses: Self control key for maturation.

Published in:

Nature Reviews Immunology, 2013, v. 13, n. 4, p. 224, doi. 10.1038/nri3439

By:

Bordon, Yvonne

Publication type:

Article

Eosinophilia and Kidney Disease: More than Just an Incidental Finding?

Published in:

Journal of Clinical Medicine, 2018, v. 7, n. 12, p. 529, doi. 10.3390/jcm7120529

By:

Gauckler, Philipp;
Shin, Jae Il;
Mayer, Gert;
Kronbichler, Andreas

Publication type:

Article

Saquinavir- NO Inhibits IL-6 Production in Macrophages.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 115, n. 6, p. 499, doi. 10.1111/bcpt.12268

By:

Momčilović, Miljana;
Mangano, Katia;
Jevtić, Bojan;
Mammana, Santa;
Stošić‐Grujičić, Stanislava;
Nicoletti, Ferdinando;
Miljković, Djordje

Publication type:

Article

Beneficial effects of naringenin and morin on interleukin-5 and reactive oxygen species production in BALB/c mice with ovalbumin-induced asthma.

Published in:

Korean Journal of Physiology & Pharmacology, 2021, v. 25, n. 6, p. 555, doi. 10.4196/kjpp.2021.25.6.555

By:

Peng Qi;
Chunhua Wei;
Dianbo Kou

Publication type:

Article

Mepolizumab—a novel option for the treatment of hypereosinophilic syndrome in childhood.

Published in:

Pediatric Allergy & Immunology, 2018, v. 29, n. 1, p. 28, doi. 10.1111/pai.12809

By:

Schwarz, Carsten;
Müller, Thilo;
Lau, Susanne;
Parasher, Kirn;
Staab, Doris;
Wahn, Ulrich

Publication type:

Article

Enhanced T helper 1 and 2 cytokine responses at birth associate with lower risk of middle ear infections in infancy.

Published in:

Pediatric Allergy & Immunology, 2017, v. 28, n. 1, p. 53, doi. 10.1111/pai.12658

By:

Bergroth, Eija;
Roponen, Marjut;
Karvonen, Anne M.;
Keski‐Nisula, Leea;
Remes, Sami;
Riedler, Josef;
Roduit, Caroline;
Dalphin, Jean‐Charles;
Kaulek, Vincent;
Loss, Georg J.;
Lauener, Roger;
Hirvonen, Maija‐Riitta;
Genuneit, Jon;
Schmaußer‐Hechfellner, Elisabeth;
Renz, Harald;
Pfefferle, Petra I.;
Krauss‐Etschmann, Susanne;
Schaub, Bianca;
Mutius, Erika;
Pekkanen, Juha

Publication type:

Article

Increased serum-soluble interleukin-5 receptor alpha level precedes the development of eczema in children.

Published in:

Pediatric Allergy & Immunology, 2010, v. 21, n. 7, p. 1052, doi. 10.1111/j.1399-3038.2010.01077.x

By:

Semic-Jusufagic, Aida;
Gevaert, Philippe;
Bachert, Claus;
Murray, Clare;
Simpson, Angela;
Custovic, Adnan

Publication type:

Article

Interleukin‐5 and interleukin‐8 in relation to eosinophils and neutrophils in nasal fluids from school children with seasonal allergic rhinitis.

Published in:

Pediatric Allergy & Immunology, 1999, v. 10, n. 3, p. 175, doi. 10.1034/j.1399-3038.1999.00036.x

By:

Benson, Mikael;
Strannegård, Inga‐lisa;
Wennergren, Göran;
Strannegård, Örjan

Publication type:

Article

Serum eosinophil cationic protein and interleukin-5 in children with bronchial asthma and acute bronchiolitis.

Published in:

Pediatric Allergy & Immunology, 1996, v. 7, n. 4, p. 180, doi. 10.1111/j.1399-3038.1996.tb00130.x

By:

Øymar, Knut;
Elsayed, Said;
Bjerknes, Robert

Publication type:

Article

Helicobacter pylori-Pulsed Dendritic Cells Induce H. pylori-Specific Immunity in Mice.

Published in:

Helicobacter, 2008, v. 13, n. 3, p. 200, doi. 10.1111/j.1523-5378.2008.00606.x

By:

Min Zhang;
Berndt, Bradford E.;
Eaton, Kathryn A.;
Rathinavelu, Sivaprakash;
Pierzchala, Anna;
Kao, John Y.

Publication type:

Article

Frequencies of interleukin-5 mRNA-producing cells in healthy individuals and in immunoglobulin-deficient patients, measured by in situ hybridization.

Published in:

Clinical & Experimental Immunology, 1990, v. 81, n. 3, p. 417

By:

Smith, C. I. E.;
Möller, G.;
Severinson, E.;
Hammarström, L.

Publication type:

Article

Rapid Screen of IL-5/IL-5Rα Blocking Antibodies in the HEK293-IL-5Rα-CSF2RB Transfected Cell Line.

Published in:

Biotechnology & Bioprocess Engineering, 2023, v. 28, n. 4, p. 612, doi. 10.1007/s12257-022-0315-2

By:

Li, Shijie;
Han, Fei;
Liu, Chang;
Dai, Weiyan;
Ke, Wenfeng;
Chen, Yongqi;
Fordjour, Eric;
Yang, Yankun;
Bai, Zhonghu

Publication type:

Article

Effect of PUVA, narrow-band UVB and cyclosporin on inflammatory cells of the psoriatic plaque.

Published in:

Journal of Cutaneous Pathology, 2007, v. 34, n. 3, p. 213, doi. 10.1111/j.1600-0560.2006.00591.x

By:

Erkin, Gul;
Uğur, Yeşim;
Gürer, Cansel Köse;
Aşan, Esin;
Korkusuz, Petek;
Şahin, Sedef;
Kölemen, Fikret

Publication type:

Article

Eosinophilic major basic protein and interleukin-5 in eosinophilic myositis.

Published in:

European Journal of Neurology, 2003, v. 10, n. 1, p. 35, doi. 10.1046/j.1468-1331.2003.00481.x

By:

Murata, K.;
Sugie, K.;
Takamure, M.;
Fujimoto, T.;
Ueno, S.

Publication type:

Article

Decreased expression of CCL17 in the disrupted nasal polyp epithelium and its regulation by IL-4 and IL-5.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197355

By:

Kim, Byoungjae;
Lee, Hyun-Ji;
Im, Nu-Ri;
Lee, Doh Young;
Kim, Ha Kyun;
Kang, Cha Young;
Park, Il-Ho;
Lee, Seung Hoon;
Lee, Heung-Man;
Lee, Sang Hag;
Baek, Seung-Kuk;
Kim, Tae Hoon

Publication type:

Article

Chicken Interleukin-5 is Expressed in Splenic Lymphocytes and Affects Antigen-Specific Antibody Production.

Published in:

Journal of Poultry Science, 2024, v. 61, p. 1, doi. 10.2141/jpsa.2024002

By:

Tenkai Watanabe;
Takumi Terada;
Ryo Ezaki;
Mei Matsuzaki;
Syuichi Furusawa;
Hiroyuki Horiuchi

Publication type:

Article

Benralizumab for acute thromboembolism in hypereosinophilic syndrome: a case report.

Published in:

Allergy, Asthma & Clinical Immunology, 2025, v. 21, n. 1, p. 1, doi. 10.1186/s13223-025-00967-2

By:

Nagira, Daiki;
Miyamoto, Satoshi;
Mizukoshi, Taishiro;
Yanagisawa, Atsushi;
Funauchi, Atsushi;
Kanaoka, Kensuke;
Yoshimura, Hanako;
Jo, Tatsunori;
Higashiguchi, Masayoshi;
Naito, Yujiro;
Shiroyama, Takayuki;
Tetsumoto, Satoshi;
Hirata, Haruhiko;
Takeda, Yoshito;
Kumanogoh, Atsushi

Publication type:

Article

Allergen Induced mRNA Expression of Interleukin-5, but Not of Interleukin-4 and Interferon-γ, in Peripheral Blood Mononuclear Cells Obtained Before the Pollen Season Predicts the Clinical Efficacy of Immunotherapy for Seasonal Allergic Rhinitis.

Published in:

Scandinavian Journal of Immunology, 2000, v. 51, n. 2, doi. 10.1046/j.1365-3083.2000.00660.x

By:

Kakinoki;
Ohashi;
Nakai;
Washio;
Nasako;
Tanaka

Publication type:

Article

Relationship Between Interleukin-5 Production and Variations in Eosinophil Counts During HIV Infection in West Africa: Influence of Mycobacterium tuberculosis Infection.

Published in:

Scandinavian Journal of Immunology, 1999, v. 49, n. 2, p. 203, doi. 10.1046/j.1365-3083.1999.00467.x

By:

DIAGBOUGA;
ALDEBERT;
FUMOUX;
CAPRON;
LEDRU

Publication type:

Article

In Vivo Evidence for a Non-T Cell Origin of Interleukin-5.

Published in:

Scandinavian Journal of Immunology, 1995, v. 41, n. 3, p. 288, doi. 10.1111/j.1365-3083.1995.tb03566.x

By:

Castro, A. G.;
Silva, R. A.;
Minóprió, P.;
Appelberg, R.

Publication type:

Article

Interleukin 5 Regulation of Peritoneal B-Cell Proliferation and Antibody Secretion.

Published in:

Scandinavian Journal of Immunology, 1990, v. 31, n. 1, p. 91, doi. 10.1111/j.1365-3083.1990.tb02747.x

By:

Wetzel, G. D.

Publication type:

Article

Molecular design and systematic optimization of a halogen‐bonding system between the asthma interleukin‐5 receptor and its cyclic peptide ligand.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 1, p. 1, doi. 10.1111/cbdd.14387

By:

He, Quan;
Xu, Shuanglan;
Ma, Xiaomei;
Zhou, Yinxia;
Feng, Weiqi;
Lu, Xuzhi;
Yu, Meiyue;
Chen, Zi

Publication type:

Article

Marked infiltration of eosinophils in necrotizing granulomas in the resected hepatic bed after cholecystectomy resulting from gallbladder cancer and metastatic liver cancer is associated with peculiar peripheral eosinophilia.

Published in:

Medical Molecular Morphology, 2012, v. 45, n. 1, p. 53, doi. 10.1007/s00795-011-0555-2

By:

Ohtsuki, Yuji;
Kimura, Masashi;
Watanabe, Ryohei;
Okada, Yuhei;
Teratani, Yuki;
Kurabayashi, Atsushi;
Takeuchi, Tamotsu;
Lee, Gang-Hong;
Furihata, Mutsuo

Publication type:

Article

IL-5 Exposure In Utero Increases Lung Nerve Density and Airway Reactivity in Adult Offspring.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2020, v. 62, n. 4, p. 493, doi. 10.1165/rcmb.2019-0214OC

By:

Lebold, Katie M.;
Drake, Matthew G.;
Hales-Beck, Lauren B.;
Fryer, Allison D.;
Jacoby, David B.

Publication type:

Article

Real-world study in severe eosinophilic asthma patients refractory to anti-IL5 biological agents treated with benralizumab in Spain (ORBE study).

Published in:

2021

By:

Martínez-Moragón, Eva;
García-Moguel, Ismael;
Nuevo, Javier;
Resler, Gustavo;
ORBE study investigators;
Antépara, Ignacio;
Arismendi-Núñez, Ebymar;
Casas-Maldonado, Francisco;
Dávila-González, Ignacio;
Velasco-Garrido, Jose Luis;
Díaz-Campos, Rocío;
Díaz-Donado, Carmen;
Gálvez, Beatriz;
Izquierdo, Jose Luis;
López-Viña, Antolín;
Navarro-Soriano, Cristina;
Palop-Cervera, Marta;
de Llano, Luis Pérez;
Plaza, Vicente;
Racionero-Casero, Miguel Ángel

Publication type:

journal article

Group 2 Innate Lymphoid Cell Production of IL-5 Is Regulated by NKT Cells during Influenza Virus Infection.

Published in:

PLoS Pathogens, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.ppat.1003615

By:

Gorski, Stacey Ann;
Hahn, Young S.;
Braciale, Thomas J.

Publication type:

Article

Interleukin-4 in rheumatoid arthritis patients with interstitial lung disease: a pilot study.

Published in:

Indian Journal of Medical Research, 2013, v. 138, n. 6, p. 919

By:

Hui Shen;
Liping Xia;
Jing Lu

Publication type:

Article

Characterization of Ascaris-Induced Biphasic Skin Allergic Reaction Model in Mice: Possible Roles of Mast Cells in Early-Phase and CD4-Positive T Cells in Late-Phase Reactions.

Published in:

Pharmacology, 2001, v. 63, n. 2, p. 82, doi. 10.1159/000056117

By:

Sengoku, Takanori;
Sato, Sachio;
Sakuma, Shozo;
Ogawa, Toshikazu;
Ohkubo, Yoshitaka;
Goto, Toshio

Publication type:

Article

Novel immunomodulatory function of 1,3,4-thiadiazole derivatives with leishmanicidal activity.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 8, p. 1968, doi. 10.1093/jac/dks144

By:

Pourrajab, Fatemeh;
Forouzannia, Seyed Khalil;
Tabatabaee, Seyed Ahmad

Publication type:

Article

The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-? and suppresses TH2 differentiation.

Published in:

Nature Immunology, 2012, v. 13, n. 8, p. 778, doi. 10.1038/ni.2362

By:

Kuwahara, Makoto;
Yamashita, Masakatsu;
Shinoda, Kenta;
Tofukuji, Soichi;
Onodera, Atsushi;
Shinnakasu, Ryo;
Motohashi, Shinichiro;
Hosokawa, Hiroyuki;
Tumes, Damon;
Iwamura, Chiaki;
Lefebvre, Veronique;
Nakayama, Toshinori

Publication type:

Article

Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells.

Published in:

Nature Immunology, 2011, v. 12, n. 2, p. 167, doi. 10.1038/ni.1984

By:

Islam, Sabina A;
Chang, Daniel S;
Colvin, Richard A;
Byrne, Mike H;
McCully, Michelle L;
Moser, Bernhard;
Lira, Sergio A;
Charo, Israel F;
Luster, Andrew D

Publication type:

Article

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

Published in:

Nature Immunology, 2011, v. 12, n. 1, p. 21, doi. 10.1038/ni.1962

By:

Spits, Hergen;
Di Santo, James P

Publication type:

Article

Real-world safety and effectiveness of mepolizumab for patients with eosinophilic granulomatosis with polyangiitis in Japan: A 48-week interim analysis of the MARS study.

Published in:

Modern Rheumatology, 2024, v. 34, n. 5, p. 978, doi. 10.1093/mr/road109

By:

Ishii, Tomonori;
Kunishige, Hideaki;
Kobayashi, Tamami;
Hayashi, Etsuko;
Komatsubara, Masaki;
Ishii, Takeo;
Alfonso-Cristancho, Rafael;
Tamaoki, Jun;
Howarth, Peter

Publication type:

Article

Interleukin 5-producing ST2+ memory Th2 cells in IgG4-related dacryoadenitis and sialadenitis.

Published in:

Modern Rheumatology, 2019, v. 29, n. 5, p. 856, doi. 10.1080/14397595.2018.1526357

By:

Motohisa Yamamoto;
Ken-ichi Takano;
Ryuta Kamekura;
Satsuki Aochi;
Chisako Suzuki;
Shingo Ichimiya;
Hiroshi Nakase;
Tetsuo Himi;
Hiroki Takahashi

Publication type:

Article

Characterization of a murine model with arteritis induced by Nod1 ligand, FK565: A comparative study with a CAWS-induced model.

Published in:

Modern Rheumatology, 2017, v. 27, n. 6, p. 1024, doi. 10.1080/14397595.2017.1287150

By:

Ryuji Ohashi;
Ryuji Fukazawa;
Makoto Watanabe;
Koji Hashimoto;
Nobuko Suzuki;
Noriko Nagi-Miura;
Naohito Ohno;
Akira Shimizu;
Yasuhiko Itoh

Publication type:

Article

Churg-Strauss syndrome associated with elevated levels of serum interleukin-5 and T cell receptor-Cβ gene rearrangement.

Published in:

Modern Rheumatology, 2011, v. 21, n. 1, p. 76, doi. 10.3109/s10165-010-0341-3

By:

Horai, Yoshiro;
Miyamura, Tomoya;
Takahama, Soichiro;
Hirata, Akie;
Nakamura, Masataka;
Ando, Hitoshi;
Minami, Rumi;
Yamamoto, Masahiro;
Suematsu, Eiichi

Publication type:

Article

Does mepolizumab ease intestinal parasitic infections?

Published in:

Eurasian Journal of Pulmonology, 2025, v. 27, n. 1, p. 59, doi. 10.14744/ejp.2024.1006

By:

Aksu, Kurtuluş;
Tuğlu, Hatice Çelik;
Yağdıran, Melis;
Çelik, Fatma Dindar;
Akkale, Özgür;
Telli, Onur

Publication type:

Article

A Subset of Extreme Human Immunodeficiency Virus (HIV) Controllers Is Characterized by a Small HIV Blood Reservoir and a Weak T-Cell Activation Level.

Published in:

Open Forum Infectious Diseases, 2017, v. 4, n. 2, p. 1, doi. 10.1093/ofid/ofx064

By:

Canouï, Etienne;
Lécuroux, Camille;
Avettand-Fenoël, Véronique;
Gousset, Marine;
Rouzioux, Christine;
Saez-Cirion, Asier;
Meyer, Laurence;
Boufassa, Faroudy;
Lambotte, Olivier;
Noël, Nicolas

Publication type:

Article

Poster Abstracts Others—Published Only.

Published in:: 2005
Publication type:: Abstract

Optimization of sputum-processing methods for the measurement of interleukin-5: Effects of protease inhibition.

Published in:

Respirology, 2002, v. 7, n. 2, p. 111, doi. 10.1046/j.1440-1843.2002.00380.x

By:

SIMPSON, JODIE L;
GIBSON, PETER G;
WARK, PETER A. B

Publication type:

Article

The effect of glucocorticoid on T cell activation, interleukin-4 and interleukin-5 mRNA expression in patients with steroid-resistant asthma.

Published in:

Respirology, 1999, v. 4, n. 4, p. 427, doi. 10.1046/j.1440-1843.1999.00217.x

By:

Sun, Yongchang;
Luo, Weici

Publication type:

Article

Suppressive effects of primed eosinophils on single epicutaneous sensitization through regulation of dermal dendritic cells.

Published in:

Experimental Dermatology, 2016, v. 25, n. 7, p. 548, doi. 10.1111/exd.12998

By:

Lin, Jing ‐ Yi;
Ta, Yng ‐ Cun;
Liu, I ‐ Lin;
Chen, Hsi ‐ Wen;
Wang, Li ‐ Fang

Publication type:

Article

Comparative Insights on IL-5 Targeting with Mepolizumab and Benralizumab: Enhancing EGPA Treatment Strategies.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 4, p. 544, doi. 10.3390/biom15040544

By:

Shiomi, Mayu;
Watanabe, Ryu;
Ishihara, Ryuhei;
Tanaka, Sayaka;
Nakazawa, Takashi;
Hashimoto, Motomu

Publication type:

Article

Pharmacokinetics and pharmacodynamics of mepolizumab, an anti-interleukin 5 monoclonal antibody, in healthy Japanese male subjects.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 2, p. 102, doi. 10.1002/cpdd.205

By:

Tsukamoto, Naohiro;
Takahashi, Naoki;
Itoh, Hiroshi;
Pouliquen, Isabelle

Publication type:

Article

Interleukin-5-induced granulocyte activation in atopic patients.

Published in:

British Journal of Dermatology, 1991, v. 125, n. 2, p. 108, doi. 10.1111/j.1365-2133.1991.tb06056.x

By:

Kapp, A.;
Zeck-Kapp, Gabriele

Publication type:

Article

Regressing atypical histiocytosis and lymphomatoid papulosis: variants of the same disorder?

Published in:

British Journal of Dermatology, 1990, v. 123, n. 4, p. 515

By:

Cerio, R.;
Black, M.M.

Publication type:

Article