Works about INTEGRASE inhibitors

Results: 440

De Novo Design of HIV‐1 Integrase‐LEDGF/p75 Inhibitors Through Deep Reinforcement Learning and Virtual Screening.

Published in:

Journal of Chemometrics, 2025, v. 39, n. 5, p. 1, doi. 10.1002/cem.70037

By:

Sun, Hai‐Bo;
Wu, Hai‐Long;
Wang, Tong;
Chen, An‐Qi;
Yu, Ru‐Qin

Publication type:

Article

Influence of the Type of Antiretroviral Treatment on the Time to Reach High Pharmacotherapy Complexity in People Living With HIV.

Published in:

Annals of Pharmacotherapy, 2025, v. 59, n. 6, p. 511, doi. 10.1177/10600280241291738

By:

Contreras Macías, Enrique;
Robustillo Cortés, María de las Aguas;
Blanco Ramos, José Ramón;
Morillo Verdugo, Ramón

Publication type:

Article

Dolutegravir-induced hand-foot skin reaction in a seropositive male: A rare presentation.

Published in:

Indian Journal of Pharmacology, 2024, v. 56, n. 1, p. 55, doi. 10.4103/ijp.ijp_258_23

By:

Gayen, Tirthankar;
Baisya, Subhasmita;
Sarawgi, Devansi;
Sen, Sumit

Publication type:

Article

High incidence of delayed graft function in HIV-infected kidney transplant recipients.

Published in:

Transplant International, 2013, v. 26, n. 9, p. 893, doi. 10.1111/tri.12147

By:

Mazuecos, Auxiliadora;
Fernandez, Ana;
Zarraga, Sofia;
Andres, Amado;
Rodriguez-Benot, Alberto;
Jimenez, Carlos;
Gomez, Ernesto;
Paul, Javier;
Jimeno, Luisa;
Fernandez, Constatino;
Burgos, Dolores;
Sanchez-Fructuoso, Ana;
Guirado, Lluis

Publication type:

Article

Novel 1,3-Indanedione-Thiazole Hybrids as Small-Molecule SARS-COV-2 Main Protease Inhibitors With Potential anti-Coronaviral Activity.

Published in:

Polycyclic Aromatic Compounds, 2024, v. 44, n. 10, p. 6941, doi. 10.1080/10406638.2024.2318442

By:

Farghaly, Thoraya A.;
Masaret, Ghada S.;
Abdulwahab, Hanan Gaber

Publication type:

Article

Design, Synthesis, Biological Activity, and Molecular Modeling of Novel Spiroquinazoline Derivatives as Acetylcholinesterase Inhibitors for Alzheimer Disease.

Published in:

Polycyclic Aromatic Compounds, 2023, v. 43, n. 9, p. 8082, doi. 10.1080/10406638.2022.2144911

By:

Shtaiwi, Majed;
Aljaar, Nayyef;
Al-Najjar, Lana;
Malakar, Chandi C.;
Shtaiwi, Amneh;
Abu-Sini, Mohammad;
Al-Refai, Mahmoud

Publication type:

Article

Synthesis of Three Key Impurities of Drug Dolutegravir: An Inhibitor of HIV-1 Integrase.

Published in:

Polycyclic Aromatic Compounds, 2023, v. 43, n. 4, p. 3706, doi. 10.1080/10406638.2022.2077772

By:

Garrepalli, Sailaja;
Gudipati, Ramesh;
Ravindhranath, Kunta;
Pal, Manojit

Publication type:

Article

Xenotransplantation Literature Update January/February 2021.

Published in:

Xenotransplantation, 2021, v. 28, n. 3, p. 1, doi. 10.1111/xen.12685

By:

Rao, Joseph Sushil;
Matson, Anders W.;
Taylor, R. Travis;
Burlak, Christopher

Publication type:

Article

High viral suppression and detection of dolutegravir-resistance associated mutations in treatment-experienced Tanzanian adults living with HIV-1 in Dar es Salaam.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47795-1

By:

Bwire, George M.;
Aiko, Beatrice Godwin;
Mosha, Idda H.;
Kilapilo, Mary S.;
Mangara, Alli;
Kazonda, Patrick;
Swai, Janeth P.;
Swalehe, Omary;
Jordan, Michael R.;
Vercauteren, Jurgen;
Sando, David;
Temba, David;
Shao, Amani;
Mauka, Wilhellmuss;
Decouttere, Catherine;
Vandaele, Nico;
Sangeda, Raphael Z.;
Killewo, Japhet;
Vandamme, Anne-Mieke

Publication type:

Article

Broad synergistic antiviral efficacy between a novel elite controller-derived dipeptide and antiretrovirals against drug-resistant HIV-1.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 1, doi. 10.3389/fcimb.2024.1334126

By:

Giammarino, Federica;
Sönnerborg, Anders;
Ceña-Diez, Rafael

Publication type:

Article

Weight gain following switch to integrase inhibitors from non-nucleoside reverse transcriptase or protease inhibitors in people living with HIV in the United States: analyses of electronic medical records and prescription claims.

Published in:

Current Medical Research & Opinion, 2023, v. 39, n. 9, p. 1237, doi. 10.1080/03007995.2023.2239661

By:

Tse, Jenny;
Prajapati, Girish;
Zhao, Xiaohui;
Near, Aimee M.;
Kumar, Princy N.

Publication type:

Article

POM as a quick bioinformatic platform to select flavonoids and their metabolites as potential and efficient HIV-1 integrase inhibitors.

Published in:

Research on Chemical Intermediates, 2013, v. 39, n. 3, p. 1227, doi. 10.1007/s11164-012-0679-6

By:

Hadda, Taibi;
Fergoug, Teffaha;
Warad, Ismail;
Masand, Vijay;
Sheikh, Javed

Publication type:

Article

CD8<sup>+</sup> T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42435-8

By:

Policicchio, Benjamin B.;
Cardozo-Ojeda, Erwing Fabian;
Xu, Cuiling;
Ma, Dongzhu;
He, Tianyu;
Raehtz, Kevin D.;
Sivanandham, Ranjit;
Kleinman, Adam J.;
Perelson, Alan S.;
Apetrei, Cristian;
Pandrea, Ivona;
Ribeiro, Ruy M.

Publication type:

Article

Ultra-long-acting in-situ forming implants with cabotegravir protect female macaques against rectal SHIV infection.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36330-5

By:

Young, Isabella C.;
Massud, Ivana;
Cottrell, Mackenzie L.;
Shrivastava, Roopali;
Maturavongsadit, Panita;
Prasher, Alka;
Wong-Sam, Andres;
Dinh, Chuong;
Edwards, Tiancheng;
Mrotz, Victoria;
Mitchell, James;
Seixas, Josilene Nascimento;
Pallerla, Aryani;
Thorson, Allison;
Schauer, Amanda;
Sykes, Craig;
De la Cruz, Gabriela;
Montgomery, Stephanie A.;
Kashuba, Angela D. M.;
Heneine, Walid

Publication type:

Article

A quantitative structure–activity relationship study on HIV-1 integrase inhibitors using genetic algorithm, artificial neural networks and different statistical methods.

Published in:

Arabian Journal of Chemistry, 2016, v. 9, p. S185, doi. 10.1016/j.arabjc.2011.03.006

By:

Ghasemi, Ghasem;
Nirouei, Mahyar;
Shariati, Shahab;
Abdolmaleki, Parviz;
Rastgoo, Zinab

Publication type:

Article

Prevalence, treatment, and factors associated with cryptococcal meningitis post introduction of integrase inhibitors antiretroviral based regimens among People Living with HIV in Tanzania.

Published in:

PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0294940

By:

Minja, Makyao;
Mbilinyi, Tusaligwe;
Mkinga, Bryceson;
Philipo, Erick G.;
Owenya, Joyce;
Kilonzi, Manase

Publication type:

Article

Congenital malformations and preeclampsia associated with integrase inhibitor use in pregnancy: A single-center analysis.

Published in:

PLoS ONE, 2023, v. 18, n. 6, p. 1, doi. 10.1371/journal.pone.0276473

By:

Smith, Christiana;
Fought, Angela J.;
Sung, Joyce F.;
McKinney, Jennifer R.;
Metz, Torri D.;
Fetters, Kirk B.;
Lazarus, Sarah;
Capraro, Shannon;
Barr, Emily;
Glenny, Carrie;
Buehler, Jenna;
Weinberg, Adriana

Publication type:

Article

Adoption is not associated with immunological and virological outcomes in children with perinatally acquired HIV infection in the Netherlands.

Published in:

PLoS ONE, 2023, v. 18, n. 5, p. 1, doi. 10.1371/journal.pone.0284395

By:

Van Den Hof, Malon;
Smit, Colette;
Rossum, Annemarie M. C. Van;
Fraaij, Pieter L. A.;
Wolfs, Tom F. W.;
Geelen, Sibyl P. M.;
Scherpbier, Henriette J.;
Schölvinck, Elisabeth H.;
Aerde, Koen Van;
Reiss, Peter;
Wit, Ferdinand W. N. M.;
Pajkrt, Dasja

Publication type:

Article

Human iPSC-derived neurons reveal NMDAR-independent dysfunction following HIV-associated insults.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2023.1353562

By:

Starr, Alexander;
Nickoloff-Bybel, Emily;
Abedalthaqafi, Razan;
Albloushi, Naela;
Jordan-Sciutto, Kelly L.

Publication type:

Article

Anti‐tumour effects of PIM kinase inhibition on progression and chemoresistance of hepatocellular carcinoma.

Published in:

Journal of Pathology, 2020, v. 252, n. 1, p. 65, doi. 10.1002/path.5492

By:

Leung, Ming‐Sum;
Chan, Kristy Kwan‐Shuen;
Dai, Wen‐Juan;
Wong, Cheuk‐Yan;
Au, Kwan‐Yung;
Wong, Pik‐Ying;
Wong, Carmen Chak‐Lui;
Lee, Terence Kin‐Wah;
Ng, Irene Oi‐Lin;
Kao, Weiyuan John;
Lo, Regina Cheuk‐Lam

Publication type:

Article

Accumulation of Multiple Mutations In Vivo Confers Cross-Resistance to New and Existing Integrase Inhibitors.

Published in:

2018

By:

Zhang, Wendy W;
Cheung, Peter K;
Oliveira, Natalia;
Robbins, Marjorie A;
Harrigan, P Richard;
Shahid, Aniqa

Publication type:

journal article

Semen as the Way Forward to Understand HIV-1 Transmission.

Published in:

2016

By:

Coombs, Robert W.;
Krieger, John N.

Publication type:

Editorial

Successful Prevention of Transmission of Integrase Resistance in the Swiss HIV Cohort Study.

Published in:

2016

By:

Scherrer, Alexandra U.;
Wan-Lin Yang;
Kouyos, Roger D.;
Böni, Jürg;
Yerly, Sabine;
Klimkait, Thomas;
Aubert, Vincent;
Cavassini, Matthias;
Battegay, Manuel;
Hauser, Christoph;
Calmy, Alexandra;
Schmid, Patrick;
Bernasconi, Enos;
Günthard, Huldrych F.;
Yang, Wan-Lin;
Swiss HIV Cohort Study

Publication type:

journal article

Safety and Efficacy of Dolutegravir in Treatment-Experienced Subjects With Raltegravir-Resistant HIV Type 1 Infection: 24-Week Results of the VIKING Study.

Published in:

Journal of Infectious Diseases, 2013, v. 207, n. 5, p. 740

By:

Eron, Joseph J.;
Clotet, Bonaventura;
Durant, Jacques;
Katlama, Christine;
Kumar, Princy;
Lazzarin, Adriano;
Poizot-Martin, Isabelle;
Richmond, Gary;
Soriano, Vincent;
Ait-Khaled, Mounir;
Fujiwara, Tamio;
Huang, Jenny;
Min, Sherene;
Vavro, Cindy;
Yeo, Jane

Publication type:

Article

HIV-1 Integrase Inhibitor Resistance and Its Clinical Implications.

Published in:

2011

By:

Blanco, Jose-Luis;
Varghese, Vici;
Rhee, Soo-Yon;
Gatell, Jose M.;
Shafer, Robert W.

Publication type:

Opinion

A Reduced Grade of Liver Fibro-steatosis after Raltegravir, Maraviroc and Fosamprenavir in an HIV/HCV Co-infected Patient with Chronic Hepatitis, Cardiomyopathy, Intolerance to Nelfinavir and a Marked Increase of Serum Creatine Phosphokinase Levels Probably Related to Integrase Inhibitor Use

Published in:

West Indian Medical Journal, 2012, v. 61, n. 9, p. 932, doi. 10.7727/wimj.2011.194

By:

Antoni, A Degli;
Weimer, L. E.;
Manfredi, R.;
Fragola, V.;
Ferrari, C.

Publication type:

Article

Application of an R-group search technique in the molecular design of HIV-1 integrase inhibitors.

Published in:

Journal of the Serbian Chemical Society, 2016, v. 81, n. 4, p. 383, doi. 10.2298/JSC150826003T

By:

JIAN-BO TONG;
MIN BAI;
XIANG ZHAO

Publication type:

Article

Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections.

Published in:

Immunity & Ageing, 2019, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12979-019-0153-z

By:

Ji, Yingjie;
Dang, Xindi;
Nguyen, Lam Ngoc Thao;
Nguyen, Lam Nhat;
Zhao, Juan;
Cao, Dechao;
Khanal, Sushant;
Schank, Madison;
Wu, Xiao Y.;
Morrison, Zheng D.;
Zou, Yue;
El Gazzar, Mohamed;
Ning, Shunbin;
Wang, Ling;
Moorman, Jonathan P.;
Yao, Zhi Q.

Publication type:

Article

A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.

Published in:

PLoS Pathogens, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.ppat.1009671

By:

Maehigashi, Tatsuya;
Ahn, Seohyun;
Kim, Uk-Il;
Lindenberger, Jared;
Oo, Adrian;
Koneru, Pratibha C.;
Mahboubi, Bijan;
Engelman, Alan N.;
Kvaratskhelia, Mamuka;
Kim, Kyungjin;
Kim, Baek

Publication type:

Article

Identification of Influenza PA N Endonuclease Inhibitors via 3D-QSAR Modeling and Docking-Based Virtual Screening.

Published in:

Molecules, 2021, v. 26, n. 23, p. 7129, doi. 10.3390/molecules26237129

By:

Zhang, Chao;
Xiang, Junjie;
Xie, Qian;
Zhao, Jing;
Zhang, Hong;
Huang, Erfang;
Shaw, Pangchui;
Liu, Xiaoping;
Hu, Chun

Publication type:

Article

Studies towards the Design and Synthesis of Novel 1,5-Diaryl-1 H -imidazole-4-carboxylic Acids and 1,5-Diaryl-1 H -imidazole-4-carbohydrazides as Host LEDGF/p75 and HIV-1 Integrase Interaction Inhibitors.

Published in:

Molecules, 2021, v. 26, n. 20, p. 6203, doi. 10.3390/molecules26206203

By:

Rashamuse, Thompho J.;
Fish, Muhammad Q.;
Coyanis, E. Mabel;
Bode, Moira L.

Publication type:

Article

Discovery of Novel Integrase Inhibitors Acting outside the Active Site Through High-Throughput Screening.

Published in:

Molecules, 2019, v. 24, n. 20, p. 3675, doi. 10.3390/molecules24203675

By:

Aknin, Cindy;
Smith, Elena A.;
Marchand, Christophe;
Andreola, Marie-Line;
Pommier, Yves;
Metifiot, Mathieu

Publication type:

Article

Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives.

Published in:

Molecules, 2016, v. 21, n. 9, p. 1198, doi. 10.3390/molecules21091198

By:

Guan-Nan Liu;
Rong-Hua Luo;
Yu Zhou;
Xing-Jie Zhang;
Jian Li;
Liu-Meng Yang;
Yong-Tang Zheng;
Hong Liu

Publication type:

Article

Integrase Inhibitor Prodrugs: Approaches to Enhancing the Anti-HIV Activity of â-Diketo Acids.

Published in:

Molecules, 2015, v. 20, n. 7, p. 12623, doi. 10.3390/molecules200712623

By:

Nair, Vasu;
Okello, Maurice

Publication type:

Article

Bictegravir/emtricitabine/tenofovir Alafenamide for the Treatment of People Living with HIV.

Published in:

2022

By:

Mallolas, Josep

Publication type:

Interview

Synthesis of 3-amino-8-hydroxy-2-methyl-1,6-dioxo-2,7-diazaspiro[4.4]non-3-ene-4-carbonitriles.

Published in:

Russian Journal of Organic Chemistry, 2015, v. 51, n. 8, p. 1189, doi. 10.1134/S1070428015080230

By:

Fedoseev, S.;
Belikov, M.;
Lipin, K.;
Ershov, O.;
Nasakin, O.

Publication type:

Article

Role of Human Papillomavirus (HPV), Estrogen and Apobec3B Axis in Breast Cancer Initation.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2017, v. 13, p. 14

By:

Ohba, Kenji;
Pei Pei Chong;
Naoki Yamamoto

Publication type:

Article

Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90678-6

By:

Prats, Anna;
Martínez-Zalacaín, Ignacio;
Mothe, Beatriz;
Negredo, Eugènia;
Pérez-Álvarez, Núria;
Garolera, Maite;
Domènech-Puigcerver, Sira;
Coll, Pep;
Meulbroek, Michael;
Chamorro, Anna;
Fumaz, Carmina R.;
Ferrer, Maria J.;
Clotet, Bonaventura;
Soriano-Mas, Carles;
Muñoz-Moreno, Jose A.

Publication type:

Article

The safety and efficacy of PD-1 inhibitors in patients with advanced cancers and HIV/AIDS in China.

Published in:

Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1248790

By:

Yu Xiong;
Pingzheng Mo;
Yajun Yan;
Shan Wang;
Ke Zhuang;
Zhiyong Ma;
Xiaoping Chen;
Liping Deng;
Yong Xiong;
Di Deng;
Yongxi Zhang

Publication type:

Article

Natural killer cells induce HIV-1 latency reversal after treatment with pan-caspase inhibitors.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1067767

By:

Milão, Joana Furtado;
Love, Luca;
Gourgi, George;
Derhaschnig, Lukas;
Svensson, J. Peter;
Sönnerborg, Anders;
van Domselaar, Robert

Publication type:

Article

The role of dolutegravir in the management of HIV infection.

Published in:

Infection & Drug Resistance, 2015, v. 8, p. 19, doi. 10.2147/IDR.S58706

By:

Miller, Misty M.;
Liedtke, Michelle D.;
Lockhart, Staci M.;
athbun, R. Chris

Publication type:

Article

Long-term efficacy and safety of raltegravir in the management of HIV infection.

Published in:

Infection & Drug Resistance, 2014, v. 7, p. 73, doi. 10.2147/IDR.S40168

By:

Liedtke, Michelle D.;
Tomlin, C. Ryan;
Lockhart, Staci M.;
Miller, Misty M.;
Rathbun, R. Chris

Publication type:

Article

Metformin‐sensitized NSCLC cells to osimertinib via AMPK‐dependent autophagy inhibition.

Published in:

Clinical Respiratory Journal, 2019, v. 13, n. 12, p. 781, doi. 10.1111/crj.13091

By:

Chen, Hengyi;
Lin, Caiyu;
Lu, Conghua;
Wang, Yubo;
Han, Rui;
Li, Li;
Hao, Shuai;
He, Yong

Publication type:

Article

Incidence of low-level viremia and its impact on virologic failure among people living with HIV who started an integrase strand transfer inhibitors: a longitudinal cohort study.

Published in:

BMC Infectious Diseases, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12879-023-08906-5

By:

Lao, Xiaojie;
Zhang, Hanxi;
Deng, Meiju;
Li, Qun;
Xiao, Qing;
He, Lin;
Ma, Liying;
Song, Aqian;
Liang, Xuelei;
Yu, Fengting;
Zhao, Hongxin;
Zhang, Fujie

Publication type:

Article

The impact of integrase inhibitors on steatosis and fibrosis biomarkers in persons with HIV naïve to antiretroviral therapy.

Published in:

BMC Infectious Diseases, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12879-023-08530-3

By:

Fernandes, Sara Rodrigues;
Leite, Ana Rita;
Lino, Rita;
Guimarães, André Rodrigues;
Pineiro, Carmela;
Serrão, Rosário;
Freitas, Paula

Publication type:

Article

Cabotegravir.

Published in:: Australian Prescriber, 2022, v. 45, n. 4, p. 134, doi. 10.18773/austprescr.2022.039
Publication type:: Article

Bictegravir/emtricitabine/tenofovir alafenamide.

Published in:: Australian Prescriber, 2019, v. 42, n. 2, p. 68, doi. 10.18773/austprescr.2019.016
Publication type:: Article

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial.

Published in:

2016

By:

Serrano-Villar, Sergio;
Sainz, Talia;
Ma, Zhong-Min;
Utay, Netanya S.;
Chun, Tae-Wook;
Mann, Surinder;
Kashuba, Angela D.;
Siewe, Basile;
Albanese, Anthony;
Troia-Cancio, Paolo;
Sinclair, Elizabeth;
Somasunderam, Anoma;
Yotter, Tammy;
Deeks, Steven G.;
Landay, Alan;
Pollard, Richard B.;
Miller, Christopher J.;
Moreno, Santiago;
Asmuth, David M.

Publication type:

Correction Notice

Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial.

Published in:

PLoS Pathogens, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.ppat.1005381

By:

Serrano-Villar, Sergio;
Sainz, Talia;
Ma, Zhong-Min;
Utay, Netanya S.;
Wook-Chun, Tae;
Mann, Surinder;
Kashuba, Angela D.;
Siewe, Basile;
Albanese, Anthony;
Troia-Cancio, Paolo;
Sinclair, Elizabeth;
Somasunderam, Anoma;
Yotter, Tammy;
Deeks, Steven G.;
Landay, Alan;
Pollard, Richard B.;
Miller, Christopher J.;
Moreno, Santiago;
Asmuth, David M.

Publication type:

Article

Explaining the Determinants of First Phase HIV Decay Dynamics through the Effects of Stage-dependent Drug Action.

Published in:

PLoS Computational Biology, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.pcbi.1002971

By:

Gilmore, James B.;
Kelleher, Anthony D.;
Cooper, David A.;
Murray, John M.

Publication type:

Article