Works matching DE "INSULIN synthesis inhibitors"

Results: 41

Alogliptin: A Review of its Use in the Management of Type 2 Diabetes Mellitus.

Published in:: Drugs, 2010, v. 70, n. 15, p. 2051, doi. 10.2165/11205080-000000000-00000
Publication type:: Article

Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig.

Published in:

Diabetologia, 2005, v. 48, n. 9, p. 1882, doi. 10.1007/s00125-005-1847-7

By:

Plamboeck, A.;
Holst, J. J.;
Carr, R. D.;
Deacon, C. F.

Publication type:

Article

<sup>13</sup>C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and γ-glutamyl cycle activity in a clonal pancreatic beta-cell line L. Brennan et al: γ-glutamyl cycle activity in pancreatic beta cells.

Published in:

Diabetologia, 2003, v. 46, n. 11, p. 1512, doi. 10.1007/s00125-003-1184-7

By:

Brennan, L.;
Corless, M.;
Hewage, C.;
Malthouse, J. P. G.;
McClenaghan, N. H.;
Flatt, P. R.;
Newsholme, P.

Publication type:

Article

Evaluation of an aldose reductase inhibitor on lens metabolism, ATPases and antioxidative defense in streptozotocin-diabetic rats: an intervention study.

Published in:

Diabetologia, 2000, v. 43, n. 8, p. 1048, doi. 10.1007/s001250051488

By:

Obrosova, I. G.;
Fathallah, L.

Publication type:

Article

Local and Remote Ischemia-Reperfusion Injury Is Mitigated in Mice Overexpressing Human C1 Inhibitor.

Published in:

European Surgical Research, 2004, v. 36, n. 3, p. 142, doi. 10.1159/000077255

By:

Inderbitzin, D.;
Beldi, G.;
Avital, I.;
Vinci, G.;
Candinas, D.

Publication type:

Article

Histopathological study of the hepatic and renal toxicity associated with the co-administration of Imatinib and Acetaminophen in a preclinical mouse model.

Published in:

Malaysian Journal of Pathology, 2010, v. 32, n. 1, p. 1

By:

Bmedsci, Inthisham Nassar;
Pasupati, Thanikachalam;
Judson, John Paul;
Segarra, Ignacio

Publication type:

Article

Acute Insulin Stimulation Induces Phosphorylation of the Na-Cl Cotransporter in Cultured Distal mpkDCT Cells and Mouse Kidney.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0024277

By:

Sohara, Eisei;
Rai, Tatemitsu;
Yang, Sung-Sen;
Ohta, Akihito;
Naito, Shotaro;
Chiga, Motoko;
Nomura, Naohiro;
Lin, Shih-Hua;
Vandewalle, Alain;
Ohta, Eriko;
Sasaki, Sei;
Uchida, Shinichi

Publication type:

Article

Targeted Morphoproteomic Profiling of Ewing's Sarcoma Treated with Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors: Response/Resistance Signatures.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018424

By:

Subbiah, Vivek;
Naing, Aung;
Brown, Robert E.;
Chen, Helen;
Doyle, Laurence;
LoRusso, Patricia;
Benjamin, Robert;
Anderson, Pete;
Kurzrock, Razelle

Publication type:

Article

Inhibition of the Nuclear Factor-κB Pathway Prevents Beta Cell Failure and Diet Induced Diabetes in Psammomys obesus.

Published in:

PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013341

By:

Friberg, Josefine;
Tonnesen, Morten F.;
Heller, Schott;
Pociot, Flemming;
Bödvarsdottir, Thóra B.;
Karlsen, Allan E.

Publication type:

Article

Caffeoylsophorose, a New Natural α-Glucosidase Inhibitor, from Red Vinegar by Fermented Purple-Fleshed Sweet Potato.

Published in:

Bioscience, Biotechnology & Biochemistry, 2004, v. 68, n. 11, p. 2239, doi. 10.1271/bbb.68.2239

By:

Matsui, Toshiro;
Ebuchi, Sumi;
Fukui, Keiichi;
Matsugano, Kazusato;
Terahara, Norihiko;
Matsumoto, Kiyoshi

Publication type:

Article

CYP26B1 Plays a Major Role in the Regulation of All-trans-Retinoic Acid Metabolism and Signaling in Human Aortic Smooth Muscle Cells.

Published in:

Journal of Vascular Research, 2010, v. 48, n. 1, p. 23, doi. 10.1159/000317397

By:

Ocaya, Pauline Ajok;
Elmabsout, Ali Ateia;
Olofsson, Peder Stefan;
Törmä, Hans;
Gidlöf, Andreas Carl;
Sirsjö, Allan

Publication type:

Article

Dapagliflozin.

Published in:: Australian Prescriber, 2013, v. 36, n. 5, p. 174
Publication type:: Article

Hyperoxia reverses glucotoxicity-induced inhibition of insulin secretion in rat INS-1 β cells.

Published in:

Bioscience, Biotechnology & Biochemistry, 2014, v. 78, n. 5, p. 843, doi. 10.1080/09168451.2014.905175

By:

Matsunaga, Tetsuro;
Li, Shiho;
Adachi, Tetsuya;
Joo, Erina;
Gu, Ning;
Yamazaki, Hanae;
Yasuda, Koichiro;
Kondoh, Takashi;
Tsuda, Kinsuke

Publication type:

Article

HSP40 Ameliorates Impairment of Insulin Secretion by Inhibiting Huntingtin Aggregation in a HD Pancreatic β Cell Model.

Published in:

Bioscience, Biotechnology & Biochemistry, 2009, v. 73, n. 8, p. 1787, doi. 10.1271/bbb.90147

By:

Cui-Fang Ye;
He Li

Publication type:

Article

4-Aminoethylamino-emodin – a novel potent inhibitor of GSK-3β– acts as an insulin-sensitizer avoiding downstream effects of activated β-catenin.

Published in:

Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 6a, p. 1276, doi. 10.1111/j.1582-4934.2009.00701.x

By:

Gebhardt, Rolf;
Lerche, Katja S.;
Götschel, Frank;
Günther, Robert;
Kolander, Jens;
Teich, Lars;
Zellmer, Sebastian;
Hofmann, Hans-Jörg;
Eger, Kurt;
Hecht, Andreas;
Gaunitz, Frank

Publication type:

Article

Caspase Inhibitor z-DEVD-fmk Attenuates Calpain and Necrotic Cell Death in Vitro and After Traumatic Brain Injury.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2004, v. 24, n. 10, p. 1119, doi. 10.1097/01.WCB.0000138664.17682.32

By:

Knoblach, Susan M.;
Alroy, Daniel A.;
Nikolaeva, Maria;
Cernak, Ibolja;
Stoica, Bogdan A.;
Faden, Alan I.

Publication type:

Article

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.

Published in:

Acta Ophthalmologica (1755375X), 2008, v. 86, p. 42, doi. 10.1111/j.1755-3768.2008.01185.x

By:

Economou, Mario A.;
Jiangmei Wu;
Vasilcanu, Daiana;
Rosengren, Linda;
All-Ericsson, Charlotta;
van der Ploeg, Ingeborg;
Menu, Eline;
Girnita, Leonard;
Axelson, Magnus;
Larsson, Olle;
Seregard, Stefan;
Kvanta, Anders

Publication type:

Article

Glycogen synthase kinase 3: A key regulator of cellular fate.

Published in:

Cellular & Molecular Life Sciences, 2007, v. 64, n. 15, p. 1930, doi. 10.1007/s00018-007-7045-7

By:

Forde, J. E.;
Dale, T. C.

Publication type:

Article

Vildagliptin prevents hypos by affecting glucagon response.

Published in:

British Journal of Hospital Medicine (17508460), 2008, v. 69, n. 10, p. 554

By:

Owen, Olwen Glynn

Publication type:

Article

PIII-16.

Published in:

Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 2, p. P62, doi. 10.1016/j.clpt.2005.12.224

By:

He, Y. L.;
Sabo, R.;
Picard, F.;
Wang, Y.;
Campestrini, J.;
Herron, J.;
Ligueros-Saylan, M.

Publication type:

Article

Allelopathic potential of dry fruits of Washingtonia filifera: Inhibition of seed germination.

Published in:

Physiologia Plantarum, 1982, v. 54, n. 3, p. 323, doi. 10.1111/j.1399-3054.1982.tb00266.x

By:

Khan, M. Ishaq

Publication type:

Article

Metabolic Control in Type 1 Diabetes: Is Adjunctive Therapy the Way Forward?

Published in:

Diabetes Therapy, 2018, v. 9, n. 5, p. 1831, doi. 10.1007/s13300-018-0496-z

By:

Warnes, Harriet;
Helliwell, Rebecca;
Pearson, Sam Matthew;
Ajjan, Ramzi A.

Publication type:

Article

Living with Type 2 Diabetes: Patient Commentary in Response to the Paper ‘SGLT2 Inhibitors in Type 2 Diabetes Management: Key Evidence and Implications for Clinical Practice’.

Published in:

Diabetes Therapy, 2018, v. 9, n. 5, p. 1729, doi. 10.1007/s13300-018-0494-1

By:

A Patient from Diabetes UK;
Evans, Marc

Publication type:

Article

Efficacy and Safety of Initial Combination Therapy in Treatment-Naïve Type 2 Diabetes Patients: A Systematic Review and Meta-analysis.

Published in:

Diabetes Therapy, 2018, v. 9, n. 5, p. 1995, doi. 10.1007/s13300-018-0493-2

By:

Cai, Xiaoling;
Gao, Xueying;
Yang, Wenjia;
Han, Xueyao;
Ji, Linong

Publication type:

Article

Ultra-Deep Pyrosequencing of Hepatitis B Virus Quasispecies from Nucleoside and Nucleotide Reverse-Transcriptase Inhibitor (NRTI)-Treated Patients and NRTI-Naive Patients.

Published in:

Journal of Infectious Diseases, 2009, v. 199, n. 9, p. 1275, doi. 10.1086/597808

By:

Margeridon-Thermet, Severine;
Shulman, Nancy S.;
Ahmed, Aijaz;
Shahriar, Rajin;
Liu, Tommy;
Chunlin Wang;
Holmes, Susan P.;
Babrzadeh, Farbod;
Gharizadeh, Baback;
Hanczaruk, Bozena;
Simen, Birgitte B.;
Egholm, Michael;
Shafer, Robert W.

Publication type:

Article

Insulin sensitizers for women with polycystic ovarian syndrome.

Published in:

Expert Review of Endocrinology & Metabolism, 2009, v. 4, n. 2, p. 183, doi. 10.1586/17446651.4.2.183

By:

Galal, Ahmed F.;
Mitwally, Mohamed F.

Publication type:

Article

Evolving uses of oral reverse transcriptase inhibitors in the HIV-1 epidemic: from treatment to prevention.

Published in:

Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-82

By:

Gupta, Ravindra K.;
Van de Vijver, David A. M. C.;
Manicklal, Sheetal;
Wainberg, Mark A.

Publication type:

Article

Insulin Effects Weigh Heavy on the Brain.

Published in:

JAMA: Journal of the American Medical Association, 2006, v. 296, n. 14, p. 1717, doi. 10.1001/jama.296.14.1717

By:

Friedrich, M.J.

Publication type:

Article

Screening for inhibitors of topoisomerase I from Lycoris radiata by combining ultrafiltration with liquid chromatography/mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2016, v. 30, p. 95, doi. 10.1002/rcm.7649

By:

Chen, Guilin;
Tian, Yongqiang;
Guo, Mingquan

Publication type:

Article

Glycogen Synthase Kinase-3β and Cathepsin B in Diabetic Endothelial Progenitor Cell Dysfunction: An Old Player Finds a New Partner.

Published in:

2014

By:

Muniyappa, Ranganath;
Sowers, James R.

Publication type:

Opinion

Palmitate-Induced NF-kappaB Activation in Monocytes Is Ameliorated by Adiponectin.

Published in:

Diabetes, 2007, v. 56, p. A599

By:

Sinha, Sandeep;
Jamaluddin, Mohammad;
Bajaj, Mandeep

Publication type:

Article

Treatment with BI 1356, a Novel and Potent DPP-IV Inhibitor, Significantly Reduces Glucose Excursions after an oGTT in Patients with Type 2 Diabetes.

Published in:

Diabetes, 2007, v. 56, p. A156

By:

Heise, Tim;
Tiessen, Renger;
Huettner, Silke;
Ring, Arne;
Ritzhaupt, Armin;
Graefe-Mody, Ulrike;
Dugi, Klaus A.

Publication type:

Article

Sitagliptin, a Selective DPP-4 Inhibitor, Improves Glycemic Control when Added to a Sulfonylurea or to a Sulfonylurea and Metformin in Patients with Type 2 Diabetes.

Published in:

Diabetes, 2007, v. 56, p. A143

By:

Hermansen, Kjeld;
Kipnes, Mark;
Luo, Edmund;
Fanurik, Debra;
Khatami, Hootan;
Stein, Peter P.

Publication type:

Article

Dominant-Negative α-Subunit of Farnesyl- and Geranyltransferase Inhibits Glucose-Stimulated, but Not KCl-Stimulated, Insulin Secretion in INS 832/13 Cells.

Published in:

Diabetes, 2007, v. 56, n. 1, p. 204, doi. 10.2337/db06-0668

By:

Veluthakal, Rajakrishnan;
Kaur, Hitchintan;
Goalstone, Marc;
Kowluru, Anjaneyulu

Publication type:

Article

The Cell Cycle Inhibitory Protein p21<sup>cip</sup> Is Not Essential for Maintaining β-Cell Cycle Arrest or β-Cell Function In Vivo.

Published in:

Diabetes, 2006, v. 55, n. 12, p. 3271, doi. 10.2337/db06-0627

By:

Cozar-Castellano, Irene;
Haught, Marcia;
Stewart, Andrew F.

Publication type:

Article

SIGNAL TRANSDUCTION (NOT INSULIN ACTION)--TRANSCRIPTIONAL REGULATION.

Published in:: Diabetes, 2005, v. 54, p. A682
Publication type:: Article

Generation of Human-Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2.

Published in:

Stem Cells, 2009, v. 27, n. 12, p. 2992, doi. 10.1002/stem.240

By:

Wenlin Li;
Hongyan Zhou;
Abujarour, Ramzey;
Saiyong Zhu;
Jin Young Joo;
Tongxiang Lin;
Ergeng Hao;
Schöler, Hans R.;
Hayek, Alberto;
Sheng Ding

Publication type:

Article

Effect of renal impairment and haemodialysis on the pharmacokinetics of gemigliptin ( LC15-0444).

Published in:

Diabetes, Obesity & Metabolism, 2014, v. 16, n. 10, p. 1028, doi. 10.1111/dom.12292

By:

Shon, J.H.;
Kim, N.;
Park, S.J.;
Oh, M.K.;
Kim, E.Y.;
Lee, S.H.;
Kim, Y.H.;
Shin, J.G.

Publication type:

Article

Efficacy and safety of initial combination therapy with alogliptin plus metformin versus either as monotherapy in drug-naïve patients with type 2 diabetes: a randomized, double-blind, 6-month study.

Published in:

Diabetes, Obesity & Metabolism, 2014, v. 16, n. 7, p. 613, doi. 10.1111/dom.12258

By:

Pratley, R. E.;
Fleck, P.;
Wilson, C.

Publication type:

Article

Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone.

Published in:

Diabetes, Obesity & Metabolism, 2005, v. 7, n. 2, p. 170, doi. 10.1111/j.1463-1326.2004.00383.x

By:

Wargent, E.;
Stocker, C.;
Augstein, P.;
Heinke, P.;
Meyer, A.;
Hoffmann, T.;
Subramanian, A.;
Sennitt, M. V.;
Demuth, H.-U.;
Arch, J. R. S.;
Cawthorne, M. A.

Publication type:

Article

MOLECULAR DOCKING STUDY REGARDING THE INTERACTIONS BETWEEN MATRIX METALLOPROTEINASES 2 AND 9 AND THEIR NATURAL INHIBITORS TIMP1 AND TIMP2.

Published in:

Studia Universitatis Vasile Goldis Seria Stiintele Vietii (Life Sciences Series), 2009, v. 19, n. 1, p. 115

By:

Petreuş, Tudor;
Cotrutz, Carmen Elena;
Neamţu, Monica;
Cotrutz, Constantin;
Neamtu, Andrei

Publication type:

Article