Works matching DE "INFLAMMASOMES"

Results: 2618

The Role of NLRP3 Inflammasome in Oral Squamous Cell Carcinoma.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 5601, doi. 10.2147/JIR.S512770

By:

Shi, Rui;
Zhuang, Xuan;
Liu, Tong;
Yao, Song-nan;
Xue, Feng-shan

Publication type:

Article

NLRP3 and Gut–Liver Axis: New Possibility for the Treatment of Alcohol‐Associated Liver Disease.

Published in:

Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 5, p. 1070, doi. 10.1111/jgh.16935

By:

Dong, Lu;
Zhang, Haotian;
Kang, Yanyu;
Wang, Fei;
Bai, Ting;
Yang, Yong

Publication type:

Article

ATP-release pannexin channels are gated by lysophospholipids.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.107067

By:

Henze, Erik;
Burkhardt, Russell N.;
Fox, Bennett William;
Schwertfeger, Tyler J.;
Gelsleichter, Eric;
Michalski, Kevin;
Kramer, Lydia;
Lenfest, Margret;
Boesch, Jordyn M.;
Hening Lin;
Schroeder, Frank C.;
Toshimitsu Kawate

Publication type:

Article

What influences the age of menopause?

Published in:

2015

By:

Fenton, Anna;
Panay, Nick

Publication type:

Editorial

Levodopa Improves Behavioral Deficits of Mice with Parkinson’s Disease Symptoms via Curbing NLRP3 Inflammasome Activation and Enhancing Tyrosine Hydroxylase Levels in the Striatum and Substantia Nigra.

Published in:

Journal of Integrative Neuroscience, 2024, v. 23, n. 1, p. 1, doi. 10.31083/j.jin2301002

By:

Xi Chen;
Zhao Wang;
Weihua Yang;
Yuejun Fu

Publication type:

Article

Gastrodin suppresses pyroptosis and exerts neuroprotective effect in traumatic brain injury model by inhibiting NLRP3 inflammasome signaling pathway.

Published in:

Journal of Integrative Neuroscience, 2022, v. 21, n. 2, p. 1, doi. 10.31083/j.jin2102072

By:

Fei Yang;
Guangzhao Li;
Bin Lin;
Kaipeng Zhang

Publication type:

Article

Correlation of NLRP3 with severity and prognosis of coronary atherosclerosis in acute coronary syndrome patients.

Published in:

Heart & Vessels, 2016, v. 31, n. 8, p. 1218, doi. 10.1007/s00380-015-0723-8

By:

Afrasyab, Altaf;
Qu, Peng;
Zhao, Yang;
Peng, Kuang;
Wang, Hongyan;
Lou, Dayuan;
Niu, Nan;
Yuan, Dajun

Publication type:

Article

Bovine milk-derived exosomes attenuate NLRP3 inflammasome and NF-κB signaling in the lung during neonatal necrotizing enterocolitis.

Published in:

Pediatric Surgery International, 2023, v. 39, n. 1, p. 1, doi. 10.1007/s00383-023-05490-2

By:

Filler, Rachel;
Yeganeh, Mina;
Li, Bo;
Lee, Carol;
Alganabi, Mashriq;
Hock, Alison;
Biouss, George;
Balsamo, Felicia;
Lee, Dorothy;
Miyake, Hiromu;
Pierro, Agostino

Publication type:

Article

GLP-1RAs inhibit the activation of the NLRP3 inflammasome signaling pathway to regulate mouse renal podocyte pyroptosis.

Published in:

Acta Diabetologica, 2024, v. 61, n. 2, p. 225, doi. 10.1007/s00592-023-02184-y

By:

Li, Xiang;
Jiang, Xiao;
Jiang, Mei;
Wang, Zhi-feng;
Zhao, Tao;
Cao, Si-ming;
Li, Qiu-Mei

Publication type:

Article

LncRNA SNHG16 regulates RAS and NF-κB pathway-mediated NLRP3 inflammasome activation to aggravate diabetes nephropathy through stabilizing TLR4.

Published in:

Acta Diabetologica, 2023, v. 60, n. 4, p. 563, doi. 10.1007/s00592-022-02021-8

By:

Liu, Yufeng;
Zhang, Mengbi;
Zhong, Haowen;
Xie, Na;
Wang, Yamei;
Ding, Su;
Su, Xiaoyan

Publication type:

Article

Allicin Mitigates Diabetic Retinopathy in Rats by Activating Phosphatase and Tensin Homolog-induced Kinase 1/Parkin-mitophagy and Inhibiting Oxidative Stress-mediated NOD-like Receptor Family Pyrin Domain Containing 3 Inflammasome.

Published in:

Journal of Physiological Investigation (JPI), 2024, v. 67, n. 4, p. 215, doi. 10.4103/ejpi.EJPI-D-24-00039

By:

Xu, Yuanyuan;
Yu, Jia

Publication type:

Article

Cinnamaldehyde, A Bioactive Compound from the Leaves of Cinnamomum osmophloeum Kaneh, Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Inhibiting the NLRP3 Inflammasome.

Published in:

Journal of Physiological Investigation (JPI), 2024, v. 67, n. 3, p. 139, doi. 10.4103/ejpi.EJPI-D-24-00017

By:

Liu, May-Lan;
Wong, Wei-Ting;
Weng, Yih-Ming;
Ho, Chen-Lung;
Hsu, Hsien-Ta;
Hua, Kuo-Feng;
Wu, Chun-Hsien;
Li, Lan-Hui

Publication type:

Article

Disulfiram attenuates lipopolysaccharide-induced acute kidney injury by suppressing oxidative stress and NLRP3 inflammasome activation in mice.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 2, p. 259, doi. 10.1093/jpp/rgab171

By:

Huang, Jie;
Wei, Shanshan;
Peng, Zhenyu;
Xiao, Zijun;
Yang, Yuanying;
Liu, Jiaqin;
Zhang, Bikui;
Li, Wenqun

Publication type:

Article

Liposomal chrysin attenuates hepatic ischaemia-reperfusion injury: possible mechanism via inhibiting NLRP3 inflammasome.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 2, p. 216, doi. 10.1093/jpp/rgab153

By:

Huang, Rui;
Zhao, Zizuo;
Jiang, Xujie;
Li, Weiwei;
Zhang, Lidan;
Wang, Bin;
Tie, Hongtao

Publication type:

Article

Dioscorea zingiberensis ameliorates diabetic nephropathy by inhibiting NLRP3 inflammasome and curbing the expression of p66Shc in high-fat diet/streptozotocin-induced diabetic mice.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 9, p. 1218, doi. 10.1093/jpp/rgab053

By:

Chaoxing Ren;
Xiaowei Zhou;
Xiaowen Bao;
Jie Zhang;
Jun Tang;
Zhiming Zhu;
Nan Zhang;
Yu Bai;
Youli Xi;
Qi Zhang;
Bo Ma

Publication type:

Article

Zanthoxylum zanthoxyloides inhibits lipopolysaccharide- and synthetic hemozoin-induced neuroinflammation in BV-2 microglia: roles of NF-κB transcription factor and NLRP3 inflammasome activation.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 1, p. 118, doi. 10.1093/jpp/rgaa019

By:

Ogunrinade, Folashade A.;
Guetchueng, Stephanie T.;
Katola, Folashade O.;
Aderogba, Mutalib A.;
Akande, Idowu S.;
Sarker, Satyajit D.;
Olajide, Olumayokun A.

Publication type:

Article

Dynamic roles of inflammasomes in inflammatory tumor microenvironment.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00154-7

By:

Jang, Jeong-Hoon;
Kim, Do-Hee;
Surh, Young-Joon

Publication type:

Article

Fish Oil Derived Omega 3 Fatty Acids Suppress Adipose NLRP3 Inflammasome Signaling in Human Obesity.

Published in:

Journal of the Endocrine Society, 2019, v. 3, n. 3, p. 504, doi. 10.1210/js.2018-00220

By:

Lee, Kailey Roberts;
Midgette, Yasmeen;
Shah, Rachana

Publication type:

Article

Systematic Analysis of Long Non-Coding RNAs in Inflammasome Activation in Monocytes/Macrophages.

Published in:

Non-Coding RNA, 2023, v. 9, n. 5, p. 50, doi. 10.3390/ncrna9050050

By:

Qian, Na;
Distefano, Rebecca;
Ilieva, Mirolyuba;
Madsen, Jens Hedelund;
Rennie, Sarah;
Uchida, Shizuka

Publication type:

Article

A190 ATP-INDUCED INFLAMMASOME ACTIVATION GENERATES MITOCHONDRIAL ROS PRODUCTION IN MACROPHAGES.

Published in:

Journal of the Canadian Association of Gastroenterology, 2021, v. 4, p. 206, doi. 10.1093/jcag/gwab002.188

By:

Bording-Jorgensen, M;
Armstrong, H;
Wine, E

Publication type:

Article

Combination therapies and other therapeutic approaches targeting the NLRP3 inflammasome and neuroinflammatory pathways: a promising approach for traumatic brain injury.

Published in:

Immunopharmacology & Immunotoxicology, 2025, v. 47, n. 2, p. 159, doi. 10.1080/08923973.2024.2444956

By:

Montazeri-Khosh, Zana;
Ebrahimpour, Ahmad;
Keshavarz, Mina;
Sheybani-Arani, MohammadHosein;
Samiei, Afshin

Publication type:

Article

Thiolutin, a selective NLRP3 inflammasome inhibitor, attenuates cyclophosphamide–induced impairment of sperm and fertility in mice.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 2, p. 172, doi. 10.1080/08923973.2023.2298894

By:

Zhu, Pengfei;
Bi, Xingyu;
Su, Dan;
Li, Xiaoling;
Chen, Bingbing;
Li, Juhua;
Zhao, Lijiang;
Wang, Yaoqing;
Xu, Suming;
Wu, Xueqing

Publication type:

Article

Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.

Published in:

Immunopharmacology & Immunotoxicology, 2023, v. 45, n. 3, p. 277, doi. 10.1080/08923973.2022.2138431

By:

Shao, Ruifei;
Lou, Xiran;
Xue, Jinfang;
Yang, Yan;
Ning, Deyuan;
Chen, Guobing;
Jiang, Lihong

Publication type:

Article

miR-155-5p/FOXO3a promotes pulmonary fibrosis in rats by mediating NLRP3 inflammasome activation.

Published in:

Immunopharmacology & Immunotoxicology, 2023, v. 45, n. 3, p. 257, doi. 10.1080/08923973.2022.2115923

By:

Wu, Ling;
Pu, Li;
Zhuang, Zhifang

Publication type:

Article

The AMPK-SIRT1-FoxO1-NF-κB signaling pathway participates in hesperetin-mediated neuroprotective effects against traumatic brain injury via the NLRP3 inflammasome.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 6, p. 970, doi. 10.1080/08923973.2022.2096464

By:

Song, Hai;
Ding, Zhongyun;
Chen, Jilin;
Chen, Tingbao;
Wang, Tinghua;
Huang, Jin

Publication type:

Article

Mechanism of miR-126 in hypoxia-reoxygenation-induced cardiomyocyte pyroptosis by regulating HMGB1 and NLRP3 inflammasome.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 4, p. 500, doi. 10.1080/08923973.2022.2054819

By:

Fei, Ling;
Zhang, Ning;
Zhang, Jun

Publication type:

Article

Capillin protects against non-alcoholic steatohepatitis through suppressing NLRP3 inflammasome activation and oxidative stress.

Published in:

Immunopharmacology & Immunotoxicology, 2021, v. 43, n. 6, p. 778, doi. 10.1080/08923973.2021.1984520

By:

Li, Bin;
Wang, Rui;
Wang, Lei;
Zhang, Gucheng;
Zhang, Yang

Publication type:

Article

Tranilast: a potential anti-Inflammatory and NLRP3 inflammasome inhibitor drug for COVID-19.

Published in:

Immunopharmacology & Immunotoxicology, 2021, v. 43, n. 3, p. 247, doi. 10.1080/08923973.2021.1925293

By:

Saeedi-Boroujeni, Ali;
Mahmoudian-Sani, Mohammad-Reza;
Nashibi, Roohangiz;
Houshmandfar, Sheyda;
Tahmaseby Gandomkari, Sima;
Khodadadi, Ali

Publication type:

Article

Inhibition of NLRP3 inflammasome: a new protective mechanism of cinnamaldehyde in endotoxin poisoning of mice.

Published in:

Immunopharmacology & Immunotoxicology, 2017, v. 39, n. 5, p. 296, doi. 10.1080/08923973.2017.1355377

By:

Xu, Feng;
Wang, Feng;
Wen, Taoqun;
Sang, Wentao;
Wang, Dejian;
Zeng, Nan

Publication type:

Article

The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation.

Published in:

Immunopharmacology & Immunotoxicology, 2017, v. 39, n. 4, p. 199, doi. 10.1080/08923973.2017.1320671

By:

Blom, Kristin;
Senkowski, Wojciech;
Jarvius, Malin;
Berglund, Malin;
Rubin, Jenny;
Lenhammar, Lena;
Parrow, Vendela;
Andersson, Claes;
Loskog, Angelica;
Fryknäs, Mårten;
Nygren, Peter;
Larsson, Rolf

Publication type:

Article

n-3 Fatty acids modulate the mRNA expression of the Nlrp3 inflammasome and Mtor in the liver of rats fed with high-fat or high-fat/fructose diets.

Published in:

Immunopharmacology & Immunotoxicology, 2016, v. 38, n. 5, p. 353, doi. 10.1080/08923973.2016.1208221

By:

Garay-Lugo, Natalia;
Domínguez-Lopez, Aarón;
Miliar García, Angel;
Aguilar Barrera, Eliud;
Gómez López, Modesto;
Gómez Alcalá, Alejandro;
Martínez Godinez, Maria de los Angeles;
Lara-Padilla, Eleazar

Publication type:

Article

GSK2656157, a PERK inhibitor, reduced LPS-induced IL-1β production through inhibiting Caspase 1 activation in macrophage-like J774.1 cells.

Published in:

Immunopharmacology & Immunotoxicology, 2016, v. 38, n. 4, p. 298, doi. 10.1080/08923973.2016.1192191

By:

Ando, Takashi;
Komatsu, Takayuki;
Naiki, Yoshikazu;
Takahashi, Kazuko;
Yokochi, Takashi;
Watanabe, Daisuke;
Koide, Naoki

Publication type:

Article

The time course of nod-like receptor family pyrin domain containing 3 inflammasome complex expressions in the testis tissue of an experimental varicocele rat model: An experimental study.

Published in:

International Journal of Reproductive Biomedicine, 2023, v. 21, n. 7, p. 577, doi. 10.18502/ijrm.v21i7.13895

By:

Asl, Hamideh Fallah;
Mashayekhi, Farideh Jalali;
Zendedel, Adib;
Baazm, Maryam

Publication type:

Article

IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02052-w

By:

Zhang, Xing;
Hu, Yangyang;
Wang, Wei;
Ji, Ru;
Li, Ziyue;
Yu, Weiyan;
Wu, Zhinian;
Xiao, Ying;
Guo, Tingyu;
Qi, Zeqiang;
Wang, Yadong;
Zhao, Caiyan

Publication type:

Article

Detection of inflammasome activation in liver tissue during the donation process as potential biomarker for liver transplantation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02042-y

By:

Mateo, Sandra V.;
Vidal-Correoso, Daniel;
Muñoz-Morales, Ana M.;
Jover-Aguilar, Marta;
Alconchel, Felipe;
de la Peña, Jesús;
Martínez-Alarcón, Laura;
López-López, Víctor;
Ríos-Zambudio, Antonio;
Cascales, Pedro;
Pons, José A.;
Ramírez, Pablo;
Pelegrín, Pablo;
Baroja-Mazo, Alberto

Publication type:

Article

Renal macrophages and NLRP3 inflammasomes in kidney diseases and therapeutics.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01996-3

By:

Islamuddin, Mohammad;
Qin, Xuebin

Publication type:

Article

SARS-CoV-2 and its ORF3a, E and M viroporins activate inflammasome in human macrophages and induce of IL-1α in pulmonary epithelial and endothelial cells.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01966-9

By:

Ambrożek-Latecka, Magdalena;
Kozlowski, Piotr;
Hoser, Grażyna;
Bandyszewska, Magdalena;
Hanusek, Karolina;
Nowis, Dominika;
Gołąb, Jakub;
Grzanka, Małgorzata;
Piekiełko-Witkowska, Agnieszka;
Schulz, Luise;
Hornung, Franziska;
Deinhardt-Emmer, Stefanie;
Kozlowska, Ewa;
Skirecki, Tomasz

Publication type:

Article

The mechanism underlying correlation of particulate matter-induced ferroptosis with inflammasome activation and iron accumulation in macrophages.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01874-y

By:

Park, Minkyung;
Park, Sujeong;
Choi, Yumin;
Cho, Young-Lai;
Kim, Min Jeong;
Park, Young-Jun;
Chung, Su Wol;
Lee, Heedoo;
Lee, Seon-Jin

Publication type:

Article

Uric acid–driven NLRP3 inflammasome activation triggers lens epithelial cell senescence and cataract formation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01900-z

By:

Lin, Hong Liang;
Wang, Sheng;
Sato, Kota;
Zhang, Yu Qiao;
He, Bei Ting;
Xu, Jing;
Nakazawa, Toru;
Qin, Yong Jie;
Zhang, Hong Yang

Publication type:

Article

Regulated cell death and inflammasome activation in gut injury following traumatic surgery in vitro and in vivo: implication for postoperative death due to multiorgan dysfunction.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01647-z

By:

Wu, Lingzhi;
Zhao, Hailin;
Zhang, Mengxu;
Sun, Qizhe;
Chang, Enqiang;
Li, Xinyi;
Ouyang, Wen;
Le, Yuan;
Ma, Daqing

Publication type:

Article

The trigger for pancreatic disease: NLRP3 inflammasome.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01550-7

By:

Liu, Tianming;
Wang, Qiang;
Du, Zhiwei;
Yin, Lu;
Li, Jiachen;
Meng, Xianzhi;
Xue, Dongbo

Publication type:

Article

Correction: Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space.

Published in:

2023

By:

Yu, Tae-Geun;
Cha, Jeong Seok;
Kim, Gijeong;
Sohn, Yoo-Kyoung;
Yoo, Youngki;
Kim, Uijin;
Song, Ji-Joon;
Cho, Hyun-Soo;
Kim, Hak-Sung

Publication type:

Correction Notice

Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01438-6

By:

Yu, Tae-Geun;
Cha, Jeong Seok;
Kim, Gijeong;
Sohn, Yoo-Kyoung;
Yoo, Youngki;
Kim, Uijin;
Song, Ji-Joon;
Cho, Hyun-Soo;
Kim, Hak-Sung

Publication type:

Article

What is the impact of inflammasome mechanisms on male infertility?

Published in:

Turkish Journal of Medical Sciences, 2023, v. 53, n. 3, p. 685, doi. 10.55730/1300-0144.5631

By:

ÖRDEK, Eser;
KATI, Bülent;
KOYUNCU, İsmail;
DEMİR, Mehmet;
YAĞMUR, İsmail;
PELİT, Eyyüp Sabri;
ÇİFTÇİ, Halil;
YENİ, Ercan

Publication type:

Article

Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 4, p. N.PAG, doi. 10.1080/23723556.2019.1610324

By:

Demarco, Benjamin;
Chen, Kaiwen W.;
Broz, Petr

Publication type:

Article

Exiting the dark side: A vital role for Caspase-3 in Yap signaling.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 4, p. 1, doi. 10.1080/23723556.2018.1494947

By:

Yosefzon, Yahav;
Fuchs, Yaron

Publication type:

Article

PTPN2 as a promoter of colon carcinoma via reduction of inflammasome activation.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 4, p. 1, doi. 10.1080/23723556.2018.1465013

By:

Spalinger, Marianne R.;
Scharl, Michael

Publication type:

Article

Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses.

Published in:

Journal of Extracellular Vesicles, 2021, v. 10, n. 10, p. 1, doi. 10.1002/jev2.12127

By:

Budden, Christina F.;
Gearing, Linden J.;
Kaiser, Romina;
Standke, Lena;
Hertzog, Paul J.;
Latz, Eicke

Publication type:

Article

Artificially Cultivated Ophiocordyceps sinensis Alleviates Diabetic Nephropathy and Its Podocyte Injury via Inhibiting P2X7R Expression and NLRP3 Inflammasome Activation.

Published in:

Journal of Diabetes Research, 2018, p. 1, doi. 10.1155/2018/1390418

By:

Wang, Chao;
Hou, Xiao-xia;
Rui, Hong-liang;
Li, Li-jing;
Zhao, Jing;
Yang, Min;
Sun, Li-jun;
Dong, Hong-rui;
Cheng, Hong;
Chen, Yi-Pu

Publication type:

Article

The novel evidence that Nox2-ROS-Nlrp3 inflammasome axis plays a pivotal role in trafficking of hematopoietic stem progenitors cells (HSPCs).

Published in:

Acta Haematologica Polonica, 2022, v. 53, n. A, p. 66

By:

Bujko, Kamila;
Adamiak, Mateusz;
Chumak, Vira;
Tracz, Michał;
Kucia, Magdalena;
Ratajczak, Mariusz Z.

Publication type:

Article