Works matching DE "INFLAMMASOMES"

Results: 2670

Correction to "Inflammasome activation and metabolic remodeling in p16‐positive aging cells aggravates high‐fat diet‐induced lung fibrosis by inhibiting NEDD4L‐mediated K48‐polyubiquitin‐dependent degradation of SGK1".

Published in:: 2025
Publication type:: Correction Notice

The NLRP3 inflammasome in urogenital cancers: structure, dual function, and therapeutic potential.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1593774

By:

Sun, Weiming;
Ma, Ruiting;
Zhao, Rui;
Tian, Jiaju;
Liu, Wenhui

Publication type:

Article

Unleashing the potential of exercise: conquering cardiovascular disease by targeting inflammasome activation.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02927-3

By:

Xiang, Lijuan;
Su, Zhanguo

Publication type:

Article

Integrating Network Pharmacology and Experimental Validation to Explore the Effect and Mechanism of Inonotus obliquus Polysaccharide in the Treatment of Rheumatoid Arthritis.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 7, p. 1017, doi. 10.3390/ph18071017

By:

Fu, Yuan;
Jiang, Tianyi;
Fang, Xizhu;
Chen, Yifang;
Li, Jiawei;
Huang, Shengnan;
Li, Fangfang;
Jin, Dan

Publication type:

Article

Monosodium Urate Crystal Deposition and Its Association With Major Cardiovascular Events.

Published in:

International Journal of Rheumatic Diseases, 2025, v. 28, n. 1, p. 1, doi. 10.1111/1756-185X.70080

By:

Su, Shiuan‐Tzuen;
Lee, Yung‐Heng;
Perng, Wuu‐Tsun;
Wei, James C.‐C.

Publication type:

Article

Angiogenin Ameliorates Endometritis by Inhibiting NLRP3 Inflammasome Activation.

Published in:

Animals (2076-2615), 2025, v. 15, n. 14, p. 2002, doi. 10.3390/ani15142002

By:

Cai, Jiangxue;
Sun, Yiran;
Yang, Hao;
Tan, Meiling;
Li, Chenxuan;
Lu, Lu;
Liu, Chenxi;
He, Bin

Publication type:

Article

Hemodialysis Intensifies NLRP3 Inflammasome Expression and Oxidative Stress in Patients with Chronic Kidney Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 14, p. 6933, doi. 10.3390/ijms26146933

By:

Ribeiro, Marcia;
Cardozo, Ludmila F. M. F.;
Coutinho-Wolino, Karen Salve;
Ribeiro-Alves, Marcelo;
Mafra, Denise

Publication type:

Article

Potential Role of Inflammasomes in Aging.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 14, p. 6768, doi. 10.3390/ijms26146768

By:

Lee, Gilyoung;
Lee, Geun-Shik

Publication type:

Article

IL-33-primed NLRP3 inflammasome in basophils drives IL-1β production and initiates atopic dermatitis inflammation.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02630-6

By:

Gunji, Yoshitaka;
Matsumura, Takayoshi;
Karasawa, Tadayoshi;
Komada, Takanori;
Baatarjav, Chintogtokh;
Komori, Satoko;
Aizawa, Hidetoshi;
Mizushina, Yoshiko;
Tsuda, Hidetoshi;
Miyake, Kensuke;
Maruyama, Takashi;
Ohmori, Tsukasa;
Karasuyama, Hajime;
Takahashi, Masafumi

Publication type:

Article

Protein regulatory network mediated by palmitoylation modifications in the pathological progression of Parkinson's disease: a narrative review.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1615001

By:

Liu, Jingjing;
Wang, Shanshan;
Fan, Lei;
Zhou, Xin;
Zhang, Sen;
Wang, Qinglu;
Dong, Panpan;
Yu, Bo

Publication type:

Article

G Protein‐Coupled Receptor 30 Attenuates Neuronal Pyroptosis Induced by Subarachnoid Hemorrhage.

Published in:

Mediators of Inflammation, 2025, v. 2025, p. 1, doi. 10.1155/mi/3585885

By:

Peng, Jun;
Hu, Xiqi;
He, Jun;
Xia, Ying;
Cervellati, Carlo

Publication type:

Article

Chronic lipopolysaccharide exposure promotes cognitive impairments by activating TRPC6-AIM2 inflammasome signaling and the regulation of ginsenoside Rg1 in Trpc6<sup>−/−</sup> mice.

Published in:

Behavioral & Brain Functions, 2025, v. 21, n. 1, p. 1, doi. 10.1186/s12993-025-00290-1

By:

Fu, Yinglin;
Zhang, Hui;
Zhu, Xing;
Liang, Haoyu;
Fan, Lei;
Su, Yong;
Li, Weiping;
Li, Weizu

Publication type:

Article

Regulation of cancer by inflammasomes: from inflammation to tumorigenesis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1611719

By:

Malvankar, Shivani;
Jaiswal, Pundrik;
Bhat, Panchami P.;
Mehto, Subhash

Publication type:

Article

Prunus mume derived extracellular vesicle-like particles alleviate experimental colitis via disrupting NEK7-NLRP3 interaction and inflammasome activation.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03567-9

By:

Lv, Qi;
Yang, Hongqiong;
Xie, Ying;
Huang, Xinjie;
Yan, Zhiqi;
Lv, Yingshan;
Cui, Yifan;
Hu, Lihong;
Qiao, Hongzhi

Publication type:

Article

Effect of advanced glycation end products formed methylglyoxal, a food-borne dicarbonyl precursor, on the exacerbation of diabetic kidney disease by NOX4/Nrf2/NLRP3 inflammasome signaling pathway in db/db mice.

Published in:

Applied Biological Chemistry, 2025, v. 68, n. 1, p. 1, doi. 10.1186/s13765-025-01011-y

By:

Lee, Hee-Weon;
Gu, Min Ji;
Kim, Donghwan;
Han, Eun Hee;
Kim, Yoonsook;
Ha, Sang Keun

Publication type:

Article

Verteporfin attenuates NLRP3 inflammasome activation to alleviate gout arthritis flares.

Published in:

Journal of Inflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12950-025-00455-9

By:

Shippy, Daniel C.;
Ulland, Tyler K.

Publication type:

Article

Bone marrow mesenchymal stem cell-derived exosomes alleviate DSS-induced inflammatory bowel disease in mice through inhibiting intestinal epithelial cell pyroptosis via delivery of TSG-6.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1601591

By:

Wu, Bihua;
Su, Shuangyan;
Wang, Xianyu;
Li, Yuwei;
Mei, Zhenghao;
Lou, Fenglin;
Guo, Le

Publication type:

Article

The Role of NLRP3 Inflammasome in Type 2 Diabetes Mellitus and Its Macrovascular Complications.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4606, doi. 10.3390/jcm14134606

By:

Karamitsos, Konstantinos;
Oikonomou, Evangelos;
Theofilis, Panagiotis;
Ikonomidis, Ignatios;
Kassi, Eva;
Lambadiari, Vaia;
Gialafos, Elias;
Tsatsaragkou, Aikaterini;
Mystakidi, Vasiliki-Chara;
Zisimos, Konstantinos;
Dimitriadis, Kyriakos;
Tousoulis, Dimitris;
Siasos, Gerasimos

Publication type:

Article

Polynucleotide Mixture Attenuates Ultraviolet B-Induced Skin Pigmentation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6399, doi. 10.3390/ijms26136399

By:

Oh, Seyeon;
Jeon, Hee-Dae;
Rho, Nark-Kyoung;
Son, Kuk Hui;
Byun, Kyunghee

Publication type:

Article

Investigating Protective Effect of Suspension of Paeoniflorin in Combination with Curcumin Against Acute Liver Injury Based on Inhibition of TLR4/NF-κB/NLRP3 Inflammatory Pathway.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6324, doi. 10.3390/ijms26136324

By:

Wu, Zhengkun;
Zhao, Yinquan;
Wang, Yang;
Li, Haohuan;
Xu, Funeng;
Zhang, Wei;
Fu, Hualin;
Yin, Lizi;
Amevor, Felix Kwame;
Lin, Juchun;
Li, Danqin;
Shu, Gang

Publication type:

Article

Inflammasome Signaling in Cardiac Arrhythmias: Linking Inflammation, Fibrosis, and Electrical Remodeling.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 5954, doi. 10.3390/ijms26135954

By:

Karakasis, Paschalis;
Pamporis, Konstantinos;
Theofilis, Panagiotis;
Milaras, Nikias;
Vlachakis, Panayotis K.;
Grigoriou, Konstantinos;
Patoulias, Dimitrios;
Karamitsos, Theodoros;
Antoniadis, Antonios P.;
Fragakis, Nikolaos

Publication type:

Article

MicroRNA-Mediated Regulation of Vascular Endothelium: From Pro-Inflammation to Atherosclerosis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 5919, doi. 10.3390/ijms26135919

By:

Silva, Vinícius Rodrigues;
Azar, Ashraf;
Goncalves, Edmilson Ricardo;
Nascimento, Thatiane Cristina de Moura;
Buchaim, Rogerio Leone;
Buchaim, Daniela Vieira;
de Oliveira, Fernando Antonio Antunes;
Nassar, Carolina Costa;
de Camargo, Tais Mendes;
Caboclo, Ricardo Farinasso;
da Cunha, Marcelo Rodrigues

Publication type:

Article

Shi Wei Ru Xiang pill alleviates acute gouty arthritis through suppressing NLRP3 inflammasome activation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1595578

By:

Wang, Na;
Zhao, Puchen;
Yin, Qin;
Li, Lizi;
Xu, Haiqi;
Yang, Can;
Tu, Yanbei;
Li, Yanfang

Publication type:

Article

Pyroptosis as a therapeutic target in preeclampsia: current research and future directions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1622550

By:

Zhu, Yongchun;
Xiang, Yuting;
Swamiappan, Sathiskumar;
Li, Zhongjun;
Peng, Xinsheng

Publication type:

Article

Comparative Analysis of Canonical Inflammasome Activation by Flow Cytometry, Imaging Flow Cytometry and High-Content Imaging.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1513, doi. 10.1007/s10753-024-02141-z

By:

Wittmann, Nico;
Bekeschus, Sander;
Biedenweg, Doreen;
Kuthning, Daniela;
Pohl, Christopher;
Gramenz, Jana;
Otto, Oliver;
Bossaller, Lukas;
Meyer-Bahlburg, Almut

Publication type:

Article

Hypothermia protects against ventilatorinduced lung injury by limiting IL-1β release and NETs formation.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101990

By:

Nosaka, Nobuyuki;
Borges, Vanessa;
Martinon, Daisy;
Crother, Timothy R;
Arditi, Moshe;
Shimada, Kenichi

Publication type:

Article

CARD8 inflammasome activation during HIV-1 cell-to-cell transmission.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102676

By:

Kulsuptrakul, Jessie;
Emerman, Michael;
Mitchell, Patrick S.

Publication type:

Article

The non-structural protein of SFTSV activates NLRP1 and CARD8 inflammasome through disrupting the DPP9-mediated ternary complex.

Published in:

PLoS Pathogens, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.ppat.1013258

By:

Liu, Pan-Pan;
Jiang, Shu-Peng;
Li, Bang;
Gui, Wen-Tao;
Qin, Xiang-Rong;
Yu, Xue-Jie

Publication type:

Article

A Case of Persistent Facial Rash in a 15‐Year‐Old: Uncovering Rosacea in the Context of Duchenne Muscular Dystrophy.

Published in:

Dermatological Reviews, 2025, v. 6, n. 3, p. 1, doi. 10.1002/der2.70040

By:

Ward, Kathleen;
Foy, Valerie;
Han, Haowei;
Choudhury, Sourab

Publication type:

Article

Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase‐1‐ and Gasdermin‐Dependent Cell Death.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451526

By:

De Loose, Joni;
Mertens, Kathleen;
Filippi, Nicolò;
Corthaut, Sam;
Benramdane, Siham;
Sim, Yani;
Van Rymenant, Yentl;
Claesen, Karen;
Vliegen, Gwendolyn;
Berg, Maya;
Gomard, Tiphanie;
Caljon, Guy;
Pintelon, Isabel;
Van Der Veken, Pieter;
De Meester, Ingrid

Publication type:

Article

mTOR Modulates NLRP3 Inflammasome Activation via Nuclear Translocation and STAT1 Inhibition.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451176

By:

González‐Dominguez, Alvaro;
Zhang, Shuling;
Boy‐Ruiz, Daniel;
Connors, Daniel;
de la Varga‐Martínez, Raquel;
Mock, Beverly A.;
Cordero, Mario D.

Publication type:

Article

Inflammasomes in Cardiovascular Diseases: Current Knowledge and Future Perspectives.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5439, doi. 10.3390/ijms26125439

By:

Caldarelli, Mario;
Franza, Laura;
Cutrupi, Sebastiano;
Menegolo, Martina;
Franceschi, Francesco;
Gasbarrini, Antonio;
Gambassi, Giovanni;
Cianci, Rossella

Publication type:

Article

Estimation of NLRP3 Inflammasome Role and some Biochemical Parameters in Patients with Chronic Kidney Diseases (CKD).

Published in:

University of Thi-Qar Journal of Science, 2023, v. 10, n. 2, p. 16, doi. 10.32792/utq/utjsci/v10i2.1063

By:

Alwan, Nada Hussain;
Faraj, Hadeel Rashid

Publication type:

Article

Combination of tauroursodeoxycholic acid and N-acetylcysteine exceeds standard treatment for acetaminophen intoxication.

Published in:

Liver International, 2017, v. 37, n. 5, p. 748, doi. 10.1111/liv.13261

By:

Paridaens, Annelies;
Raevens, Sarah;
Colle, Isabelle;
Bogaerts, Eliene;
Vandewynckel, Yves ‐ Paul;
Verhelst, Xavier;
Hoorens, Anne;
Grunsven, Leo A.;
Van Vlierberghe, Hans;
Geerts, Anja;
Devisscher, Lindsey

Publication type:

Article

Inflammasome and Inflammatory Programmed Cell Death in Chromoblastomycosis.

Published in:

Mycopathologia, 2023, v. 188, n. 1/2, p. 63, doi. 10.1007/s11046-022-00679-w

By:

Pagliari, Carla;
Kanashiro-Galo, Luciane;
Sotto, Mirian Nacagami

Publication type:

Article

Absent in melanoma 2 regulates tumor cell proliferation in glioblastoma multiforme.

Published in:

Journal of Neuro-Oncology, 2019, v. 144, n. 2, p. 265, doi. 10.1007/s11060-019-03230-y

By:

Chen, P. A.;
Shrivastava, G.;
Balcom, E. F.;
McKenzie, B. A.;
Fernandes, J.;
Branton, W. G.;
Wheatley, B. M.;
Petruk, K.;
van Landeghem, F. K. H.;
Power, Christopher

Publication type:

Article

The emerging role of pyroptosis-related inflammasome pathway in atherosclerosis.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00594-2

By:

Xu, Xiao-Dan;
Chen, Jia-Xian;
Zhu, Lin;
Xu, Shu-Ting;
Jiang, Jian;
Ren, Kun

Publication type:

Article

Relevance of the pyroptosis-related inflammasome drug targets in the Chuanxiong to improve diabetic nephropathy.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00567-5

By:

Li, ChangYan;
Ma, JingYuan;
Mali, Niroj;
Zhang, Le;
Wei, Tao;
Shi, LuYao;
Liu, Fang;
WenXing, Fan;
Yang, Jing

Publication type:

Article

Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00533-1

By:

Li, Xianzhi;
Zhou, Xiaojun;
Liu, Xigao;
Li, Xiaoyun;
Jiang, Xianzhou;
Shi, Benkang;
Wang, Shuo

Publication type:

Article

Fn14 exacerbates acute lung injury by activating the NLRP3 inflammasome in mice.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00514-4

By:

Guan, Xin-Xin;
Yang, Hui-Hui;
Zhong, Wen-Jing;
Duan, Jia-Xi;
Zhang, Chen-Yu;
Jiang, Hui-Ling;
Xiang, Yang;
Zhou, Yong;
Guan, Cha-Xiang

Publication type:

Article

Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00335-x

By:

Zhao, Xiaolan;
Zhang, Xun;
Wu, Zhao;
Mei, Jie;
Li, Lingling;
Wang, Yujue

Publication type:

Article

Resveratrol Alleviates Liver Fibrosis by Targeting Cross‐Talk Between TLR2/MyD88/ERK and NF‐κB/NLRP3 Inflammasome Pathways in Macrophages.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 3, p. 1, doi. 10.1002/jbt.70208

By:

Lei, Jin‐qing;
Xie, Qing‐li;
Li, Qing‐ping;
Qin, Shan‐yu;
Wu, Jiao‐hua;
Jiang, Hai‐xing;
Yu, Bing;
Luo, Wei

Publication type:

Article

Inhibition of NLRP3 inflammasome—A potential mechanistic therapeutic for treatment of polycystic ovary syndrome?

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23592

By:

Chamanara, Solmaz;
Hozouri, Vahid;
Irandoost, Elnaz

Publication type:

Article

Muscone attenuates susceptibility to ventricular arrhythmia by inhibiting NLRP3 inflammasome activation in rats after myocardial infarction.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 11, p. 1, doi. 10.1002/jbt.23458

By:

Yang, Shuang;
Bi, Yingying;
Wei, Yanzhao;
Li, Wei;
Liu, Jiangwen;
Mao, Tuohua;
Tang, Yanhong

Publication type:

Article

Gentiopicroside enhances the protective effect of trimetazidine against myocardial ischemia‐reperfusion injury via the AMPK/NLRP3 inflammasome signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 7, p. 1, doi. 10.1002/jbt.23366

By:

Wang, Yu;
Sheng, Yao;
Ji, Ningning;
Zhang, Hui

Publication type:

Article

Sulforaphene targets NLRP3 inflammasome to suppress M1 polarization of macrophages and inflammatory response in rheumatoid arthritis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 7, p. 1, doi. 10.1002/jbt.23362

By:

Ye, Qiao;
Yan, Tingting;
Shen, Jie;
Shi, Xianghui;
Luo, Fang;
Ren, Yanxia

Publication type:

Article

Dimethyl fumarate‐mediated Nrf2/ARE pathway activation and glibenclamide‐mediated NLRP3 inflammasome cascade inhibition alleviate type II diabetes‐associated fatty liver in rats by mitigating oxidative stress and inflammation.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 7, p. 1, doi. 10.1002/jbt.23357

By:

Dwivedi, Durgesh K.;
Jena, G. B.

Publication type:

Article

Proanthocyanidins suppress NLRP3 inflammasome and M1 macrophage polarization to alleviate severe acute pancreatitis in mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 2, p. 1, doi. 10.1002/jbt.23242

By:

Sheng, Li‐Ping;
Han, Chao‐Qun;
Ling, Xin;
Guo, Xian‐Wen;
Lin, Rong;
Ding, Zhen

Publication type:

Article

Galangin attenuates cadmium‐evoked nephrotoxicity: Targeting nucleotide‐binding domain‐like receptor pyrin domain containing 3 inflammasome, nuclear factor erythroid 2‐related factor 2, and nuclear factor kappa B signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 7, p. 1, doi. 10.1002/jbt.23059

By:

Salama, Samir A.;
Abd‐Allah, Gamil M.;
Gad, Hesham S.;
Kabel, Ahmed M.

Publication type:

Article

Sodium houttuyfonate attenuates neurological defects after traumatic brain injury in mice via inhibiting NLRP3 inflammasomes.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 9, p. 1, doi. 10.1002/jbt.22850

By:

Yao, Xiaolong;
Wang, Shengbo;
Chen, Yingchun;
Sheng, Liuqing;
Li, Huanhuan;
You, Huichao;
Ye, Jianfeng;
Zhang, Qing;
Li, Jun

Publication type:

Article