Works about INDOLEAMINE 2,3-dioxygenase

Results: 719

Indoleamine 2,3-Dioxygenase 1/Aryl Hydrocarbon Receptor Feedback Loop Mediates Anti-inflammation in lipopolysaccharide-stimulated Astrocytes to Dampen Inflammatory Neurotoxicity.

Published in:

Journal of Physiological Investigation (JPI), 2025, v. 68, n. 1, p. 1, doi. 10.4103/ejpi.EJPI-D-24-00089

By:

Gan, Yu-Ling;
Lee, Yi-Hsuan

Publication type:

Article

Decoding serotonin: the molecular symphony behind depression.

Published in:

Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1572462

By:

Shu, Yue;
Tian, Lei;
Wang, Xing;
Meng, Tinyang;
Yu, Shouyang;
Li, Yulan

Publication type:

Article

Prognostic and predictive value of IDO expression in metastatic melanoma treated with Ipilimumab.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0321937

By:

von Bubnoff, Dagmar;
Schmitt, Christina;
Goldinger, Simone M.;
Schadendorf, Dirk;
Kähler, Katharina C.;
Hafner, Christian;
Kramer, Nora;
Fröhlich, Waltraud;
Dummer, Reinhard;
Berking, Carola;
Schliep, Stefan;
Kirchberger, Michael C.;
Heinzerling, Lucie

Publication type:

Article

Noncanonical NF-κB signaling in dendritic cells is required for ATP-driven indoleamine 2,3-dioxygenase 1 induction through P2Y<sub>11</sub> receptor.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 4, p. 1, doi. 10.1093/jleuko/qiaf010

By:

Ocadlikova, Darina;
Fiordi, Benedetta;
Trabanelli, Sara;
Salvestrini, Valentina;
Ciciarello, Marilena;
Forte, Dorian;
Campazzi, Emma;
Vitali, Letizia;
Cipollitta, Serenella C;
Pegoraro, Anna;
Jandus, Camilla;
Virgilio, Francesco Di;
Adinolfi, Elena;
Cavo, Michele;
Curti, Antonio

Publication type:

Article

SARS-CoV-2 post-acute sequelae linked to inflammation via extracellular vesicles.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1501666

By:

Bachiller, Sara;
Vitallé, Joana;
Camprubí-Ferrer, Lluís;
García, Manuel;
Gallego, Isabel;
López-García, Marina;
Galvá, María Isabel;
Cañizares, Julio;
Rivas-Jeremías, Inmaculada;
Díaz-Mateos, María;
Gasca-Capote, Carmen;
Moral-Turón, Cristina;
Galán-Villamor, Lourdes;
Fontillón, María;
Sobrino, Salvador;
Cisneros, José Miguel;
López-Cortés, Luis Fernando;
Deierborg, Tomas;
Ruiz-Mateos, Ezequiel

Publication type:

Article

Tuberculosis and comorbid depression: Association with serum indoleamine 2,3-dioxygenase activity.

Published in:

Indian Journal of Pharmacology, 2025, v. 57, n. 1, p. 21, doi. 10.4103/ijp.ijp_252_23

By:

Rana, Proteesh;
Varughese, Bijo;
Roy, Vandana;
Khanna, Shreshth;
Kapoor, Seema;
Khanna, Ashwani

Publication type:

Article

Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis.

Published in:

2019

By:

Li, Nannan;
Wang, Qi;
Wang, Yan;
Sun, Anji;
Lin, Yiwei;
Jin, Ye;
Li, Xiaobai

Publication type:

Report

Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1.

Published in:

Amino Acids, 2014, v. 46, n. 9, p. 2155, doi. 10.1007/s00726-014-1766-3

By:

Pantouris, Georgios;
Serys, Martynas;
Yuasa, Hajime;
Ball, Helen;
Mowat, Christopher

Publication type:

Article

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease.

Published in:

Amino Acids, 2013, v. 45, n. 6, p. 1319, doi. 10.1007/s00726-013-1602-1

By:

Fatokun, Amos A.;
Hunt, Nicholas H.;
Ball, Helen J.

Publication type:

Article

Alpha-Fetoprotein as a Factor of Differentiation and Functional Activity of Myeloid-Derived Suppressor Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2023, v. 175, n. 4, p. 535, doi. 10.1007/s10517-023-05901-3

By:

Shardina, K. Yu.;
Zamorina, S. A.;
Timganova, V. P.;
Bochkova, M. S.;
Uzhviyuk, S. V.;
Chereshnev, V. A.

Publication type:

Article

Dual Effects of Indoleamine 2,3-Dioxygenase Inhibitors on the Therapeutic Effects of Cyclophosphamide and Cycloplatam on Ehrlich Ascites Tumor in Mice.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 157, n. 4, p. 506, doi. 10.1007/s10517-014-2602-1

By:

Bogdanova, L.;
Morozkova, T.;
Amitina, S.;
Mazhukin, D.;
Nikolin, V.;
Popova, N.;
Kaledin, V.

Publication type:

Article

Comprehensive behavioral analysis of indoleamine 2,3‐dioxygenase knockout mice.

Published in:

Neuropsychopharmacology Reports, 2018, v. 38, n. 3, p. 133, doi. 10.1002/npr2.12019

By:

Hirata, Nao;
Hattori, Satoko;
Shoji, Hirotaka;
Funakoshi, Hiroshi;
Miyakawa, Tsuyoshi

Publication type:

Article

Plasma metabolomic signatures of dual decline in memory and gait in older adults.

Published in:

GeroScience, 2023, v. 45, n. 4, p. 2659, doi. 10.1007/s11357-023-00792-8

By:

Tian, Qu;
Shardell, Michelle D.;
Kuo, Pei-Lun;
Tanaka, Toshiko;
Simonsick, Eleanor M.;
Moaddel, Ruin;
Resnick, Susan M.;
Ferrucci, Luigi

Publication type:

Article

The efficacy of indoximod upon stimulation with pro-inflammatory cytokines in triple-negative breast cancer cells.

Published in:

Immunopharmacology & Immunotoxicology, 2021, v. 43, n. 5, p. 554, doi. 10.1080/08923973.2021.1953064

By:

Guney Eskiler, Gamze;
Bilir, Cemil

Publication type:

Article

Mifepristone regulates Tregs function mediated by dendritic cells through suppressing the expression of TGF-β.

Published in:

Immunopharmacology & Immunotoxicology, 2021, v. 43, n. 1, p. 85, doi. 10.1080/08923973.2020.1867998

By:

Li, Yinghua;
Cao, Lili;
Qian, Zhida;
Guo, Qingyun;
Niu, Xiaocen;
Huang, Lili

Publication type:

Article

Survival of lymphocytes is not restricted by IDO-expressing fibroblast from rheumatoid arthritis patients.

Published in:

Immunopharmacology & Immunotoxicology, 2019, v. 41, n. 2, p. 214, doi. 10.1080/08923973.2019.1569048

By:

Massalska, Magdalena;
Kuca-Warnawin, Ewa;
Janicka, Iwona;
Plebanczyk, Magdalena;
Pawlak, Dariusz;
Dallos, Tomas;
Olwert, Anna;
Radzikowska, Anna;
Maldyk, Pawel;
Kontny, Ewa;
Maslinski, Wlodzimierz

Publication type:

Article

Vitamin D<sub>3</sub> alleviates intestinal injury in necrotizing enterocolitis and lipopolysaccharide-induced inflammatory response in dendritic cells in rats.

Published in:

Turkish Journal of Medical Sciences, 2024, v. 54, n. 5, p. 1165, doi. 10.55730/1300-0144.5895

By:

Bo KE;
Chaoyu LI;
Song LI;
Jingjing YAN;
Leke SUN

Publication type:

Article

The kynurenine pathway in patients with rheumatoid arthritis during tumor necrosis factor a inhibitors treatment.

Published in:

Rheumatology / Reumatologia, 2024, v. 62, n. 4, p. 220, doi. 10.5114/reum/191752

By:

Witoszyńska-Sobkowiak, Joanna;
Sikorska, Dorota;
Niklas, Karolina;
Żychowska, Iwona;
Rutkowski, Rafał;
Samborski, Włodzimierz

Publication type:

Article

Mediating the death of dormant tumor cells.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 4, p. 1, doi. 10.1080/23723556.2018.1458013

By:

Liu, Yuying;
Lv, Jiadi;
Huang, Bo

Publication type:

Article

Pineapple (Ananas comosus) Ameliorates Depressant-like Behaviors in Rats Induced by Lipopolysaccharide.

Published in:

Journal of Medical Sciences (1011-4564), 2024, v. 44, n. 5, p. 208, doi. 10.4103/jmedsci.jmedsci_256_23

By:

Nurrahma, Herlin Ajeng;
Meliala, Andreanyta;
Vikawati, Nura Eky;
Narwidina, Paramita;
Supriyanto, Irwan

Publication type:

Article

Indoleamine 2,3‐dioxygenase gene expression and kynurenine to tryptophan ratio correlation with nasopharyngeal carcinoma progression and survival.

Published in:

Immunity, Inflammation & Disease, 2022, v. 10, n. 9, p. 1, doi. 10.1002/iid3.690

By:

Souissi, Sameh;
Ghedira, Randa;
Macherki, Yosra;
Ben‐Haj‐Ayed, Ahlem;
Gabbouj, Sallouha;
Remadi, Yasmine;
Sfar, Imen;
Chadli, Zohra;
Aouam, Karim;
Hassine, Mohsen;
Bouaouina, Noureddine;
Zakhama, Abdelfattah;
Hassen, Elham

Publication type:

Article

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s).

Published in:

Xenotransplantation, 2017, v. 24, n. 5, p. n/a, doi. 10.1111/xen.12326

By:

Guo, Fei;
Hu, Min;
Huang, Dandan;
Zhao, Yuanfei;
Heng, Benjamin;
Guillemin, Gilles;
Lim, Chai K.;
Hawthorne, Wayne J.;
Yi, Shounan

Publication type:

Article

Effect of indoleamine 2,3-dioxygenase expressed by foetal fibroblasts on melanoma cells.

Published in:

Experimental Dermatology, 2016, v. 25, n. 10, p. 822, doi. 10.1111/exd.13058

By:

Frenard, Cécile;
Knol, Anne‐Chantal;
Lemoigne, Marie;
Khammari, Amir;
Dreno, Brigitte

Publication type:

Article

The immunosuppressive activity of myeloid-derived suppressor cells in murine Paracoccidioidomycosis relies on Indoleamine 2,3-dioxygenase activity and Dectin-1 and TLRs signaling.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39262-8

By:

Kaminski, Valéria de Lima;
Preite, Nycolas Willian;
Borges, Bruno Montanari;
dos Santos, Bianca Vieira;
Calich, Vera Lucia Garcia;
Loures, Flávio Vieira

Publication type:

Article

IgG4‐related disease is characterised by the overexpression of immunomodulatory proteins.

Published in:

Histopathology, 2022, v. 81, n. 4, p. 486, doi. 10.1111/his.14564

By:

Arora, Kshitij;
Kulkarni, Anupriya;
Pankaj, Amaya;
Desai, Niyati;
Deshpande, Vikram

Publication type:

Article

Elevated pre‐existing lymphocytic infiltrates in tumour stroma predict poor prognosis in resectable urothelial carcinoma of the bladder.

Published in:

Histopathology, 2019, v. 75, n. 3, p. 354, doi. 10.1111/his.13807

By:

Wang, Bo;
Xie, Shujie;
Bi, Junming;
Liu, Zhuowei;
Zeng, Hong;
Huang, Hao;
Xue, Miaoxin;
He, Zhihua;
Yang, Meihua;
Yu, Hao;
Huang, Jian;
Lin, Tianxin

Publication type:

Article

Inter‐ and intrapatient heterogeneity of indoleamine 2,3‐dioxygenase expression in primary and metastatic melanoma cells and the tumour microenvironment.

Published in:

Histopathology, 2019, v. 74, n. 6, p. 817, doi. 10.1111/his.13814

By:

Gide, Tuba N;
Allanson, Benjamin M;
Menzies, Alexander M;
Ferguson, Peter M;
Madore, Jason;
Saw, Robyn P M;
Thompson, John F;
Long, Georgina V;
Wilmott, James S;
Scolyer, Richard A

Publication type:

Article

Issue Information.

Published in:: Histopathology, 2019, v. 74, n. 6, p. 801, doi. 10.1111/his.13680
Publication type:: Article

PD‐L1 and IDO expression in cervical and vulvar invasive and intraepithelial squamous neoplasias: implications for combination immunotherapy.

Published in:

Histopathology, 2019, v. 74, n. 2, p. 256, doi. 10.1111/his.13723

By:

Chinn, Zachary;
Stoler, Mark H;
Mills, Anne M

Publication type:

Article

Expression of PD‐L1, indoleamine 2,3‐dioxygenase and the immune microenvironment in gastric adenocarcinoma.

Published in:

Histopathology, 2018, v. 73, n. 1, p. 124, doi. 10.1111/his.13504

By:

Patil, Pallavi A.;
Blakely, Andrew M.;
Lombardo, Kara A.;
Machan, Jason T.;
Miner, Thomas J.;
Wang, Li‐Juan;
Marwaha, Alexander S.;
Matoso, Andres

Publication type:

Article

Indoleamine 2,3-dioxygenase 1 promotes osteosarcoma progression by regulating tumor-derived exosomal miRNA hsa-miR-23a-3p.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1194094

By:

Dan Yang;
Yinxian Chen;
Zhen Ning Tony He;
Yichen Wang;
Chenghui Ke;
Yi Luo;
Sun Wang;
Qichao Ma;
Mengjie Chen;
Qing Yang;
Ziming Zhang

Publication type:

Article

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00925

By:

Vigano, Selena;
Alatzoglou, Dimitrios;
Irving, Melita;
Ménétrier-Caux, Christine;
Caux, Christophe;
Romero, Pedro;
Coukos, George

Publication type:

Article

Durable Clinical Responses and Long-Term Follow-Up of Stage III–IV Non-Small-Cell Lung Cancer (NSCLC) Patients Treated With IDO Peptide Vaccine in a Phase I Study—A Brief Research Report.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02145

By:

Kjeldsen, Julie Westerlin;
Iversen, Trine Zeeberg;
Engell-Noerregaard, Lotte;
Mellemgaard, Anders;
Andersen, Mads Hald;
Svane, Inge Marie

Publication type:

Article

The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01914

By:

Moreno, Ana C. R.;
Porchia, Bruna F. M. M.;
Pagni, Roberta L.;
Souza, Patrícia da Cruz;
Pegoraro, Rafael;
Rodrigues, Karine B.;
Aps, Luana R. de Melo Moraes;
Ferreira, Luís C. de Souza;
Barros, Tácita B.;
de Araújo, Eliseu F.;
Calich, Vera L. G.

Publication type:

Article

What May Constrain the Success of Indoleamine 2,3-Dioxygenase 1 Inhibitors in Cancer Immunotherapy?

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01879

By:

Eleftheriadis, Theodoros

Publication type:

Article

Indoleamine 2,3-Dioxygenase Expression Pattern in the Tumor Microenvironment Predicts Clinical Outcome in Early Stage Cervical Cancer.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01598

By:

Heeren, A. Marijne;
van Dijk, Ilse;
Berry, Daniella R. A. I.;
Khelil, Maryam;
Ferns, Debbie;
Kole, Jeroen;
Musters, René J. P.;
Thijssen, Victor L.;
Mom, Constantijne H.;
Kenter, Gemma G.;
Bleeker, Maaike C. G.;
de Gruijl, Tanja D.;
Jordanova, Ekaterina S.

Publication type:

Article

Expression of Indoleamine 2,3-Dioxygenase Induced by IFN-γ and TNF-α as Potential Biomarker of Prostate cancer Progression.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01051

By:

Banzola, Irina;
Mengus, Chantal;
Wyler, Stephen;
Hudolin, Tvrko;
Manzella, Gabriele;
Chiarugi, Alberto;
Boldorini, Renzo;
Sais, Giovanni;
Schmidli, Tobias S.;
Chiffi, Gabriele;
Bachmann, Alexander;
Sulser, Tullio;
Spagnoli, Giulio C.;
Provenzano, Maurizio

Publication type:

Article

Activation of the Regulatory T-Cell/Indoleamine 2,3-Dioxygenase Axis Reduces Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00950

By:

Forteza, Maria J.;
Polyzos, Konstantinos A.;
Baumgartner, Roland;
Suur, Bianca E.;
Mussbacher, Marion;
Johansson, Daniel K.;
Hermansson, Andreas;
Hansson, Göran K.;
Ketelhuth, Daniel F. J.

Publication type:

Article

High Indoleamine 2,3-Dioxygenase Is Correlated With Microvessel Density and Worse Prognosis in Breast Cancer.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00724

By:

Wei, Lijuan;
Zhu, Shanshan;
Li, Menghui;
Li, Fangxuan;
Wei, Feng;
Liu, Juntian;
Ren, Xiubao

Publication type:

Article

Beneficial or detrimental activity of regulatory T cells, indoleamine 2,3-dioxygenase, and heme oxygenase-1 in the lungs is in?uenced by the level of virulence of Mycobacterium tuberculosis strain infection.

Published in:

Frontiers in Cellular & Infection Microbiology, 2023, p. 01, doi. 10.3389/fcimb.2023.1105872

By:

Lozano-Ordaz, Vasti;
Rodriguez-Miguez, Yadira;
Ortiz-Cabrera, Angel E.;
Hernandez-Bazan, Sujhey;
Mata-Espinosa, Dulce;
Barrios-Payan, Jorge;
Saavedra, Rafael;
Hernandez-Pando, Rogelio

Publication type:

Article

The antidepressant effects of asperosaponin VI are mediated by the suppression of microglial activation and reduction of TLR4/NF-κB-induced IDO expression.

Published in:

Psychopharmacology, 2020, v. 237, n. 8, p. 2531, doi. 10.1007/s00213-020-05553-5

By:

Zhang, Jinqiang;
Yi, Saini;
Li, Yahui;
Xiao, Chenghong;
Liu, Chan;
Jiang, Weike;
Yang, Changgui;
Zhou, Tao

Publication type:

Article

Expression of Indoleamine 2,3-Dioxygenase and Infiltration of FOXP3+ Regulatory T Cells Are Associated with Aggressive Features of Papillary Thyroid Microcarcinoma.

Published in:

Thyroid, 2014, v. 24, n. 8, p. 1232, doi. 10.1089/thy.2013.0423

By:

Ryu, Han Suk;
Park, Young Soo;
Park, Hyo Jin;
Chung, Yul Ri;
Yom, Cha Kyong;
Ahn, Soon-Hyun;
Park, Young Joo;
Park, Seong Hoe;
Park, So Yeon

Publication type:

Article

Regulation of serotonin production by specific microbes from piglet gut.

Published in:

Journal of Animal Science & Biotechnology, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s40104-023-00903-7

By:

Liu, Ziyu;
Ling, Yidan;
Peng, Yu;
Han, Shuibing;
Ren, Yuting;
Jing, Yujia;
Fan, Wenlu;
Su, Yong;
Mu, Chunlong;
Zhu, Weiyun

Publication type:

Article

Inflammatory cytokines-stimulated human muscle stem cells ameliorate ulcerative colitis via the IDO-TSG6 axis.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-020-02118-3

By:

Zhang, Shengchao;
Fang, Jiankai;
Liu, Zhanhong;
Hou, Pengbo;
Cao, Lijuan;
Zhang, Yuyan;
Liu, Rui;
Li, Yanan;
Shang, Qianwen;
Chen, Yongjing;
Feng, Chao;
Wang, Guan;
Melino, Gerry;
Wang, Ying;
Shao, Changshun;
Shi, Yufang

Publication type:

Article

The therapeutic efficacy of mesenchymal stromal cells on experimental colitis was improved by the IFN-γ and poly(I:C) priming through promoting the expression of indoleamine 2,3-dioxygenase.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-020-02087-7

By:

Lim, Ji-Young;
Kim, Byung-Su;
Ryu, Da-Bin;
Kim, Tae Woo;
Park, Gyeongsin;
Min, Chang-Ki

Publication type:

Article

Immunomodulatory effects of interferon-γ on human fetal cardiac mesenchymal stromal cells.

Published in:

Stem Cell Research & Therapy, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13287-019-1489-1

By:

Grinnemo, Karl-Henrik;
Löfling, Marie;
Nathanson, Lubov;
Baumgartner, Roland;
Ketelhuth, Daniel F. J.;
Beljanski, Vladimir;
Davies, Lindsay C.;
Österholm, Cecilia

Publication type:

Article

Mislocalization of the exitatory amino-acid transporters (EAATs) in human astrocytoma and non-astrocytoma cancer cells: effect of the cell confluence.

Published in:: Journal of Biomedical Science, 2012, v. 19, n. 1, p. 10, doi. 10.1186/1423-0127-19-10
Publication type:: Article

The Role of Indoleamine 2, 3 Dioxygenase in Regulating Host Immunity to Leishmania Infection.

Published in:: Journal of Biomedical Science, 2012, v. 19, n. 1, p. 5, doi. 10.1186/1423-0127-19-5
Publication type:: Article

吲哚胺 2,3- 双加氧酶作为小儿先天性心脏病术后全身炎症反应综合征诊断标志物的价值

Published in:

Chinese Journal of Contemporary Pediatrics, 2018, v. 20, n. 1, p. 28, doi. 10.7499/j.issn.1008-8830.2018.01.006

By:

王欣;
李宗虓;
温昱鹏;
常诚

Publication type:

Article

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00620

By:

Staats Pires, Ananda;
Tan, Vanessa X.;
Heng, Benjamin;
Guillemin, Gilles J.;
Latini, Alexandra

Publication type:

Article