Works matching DE "INDOLEAMINE 2,3-dioxygenase"

Results: 732

Expression profile of the human IDO1 protein, a cancer drug target involved in tumoral immune resistance.

Published in:

OncoImmunology, 2015, v. 4, n. 5, p. 0, doi. 10.1080/2162402X.2014.1003012

By:

Vigneron, Nathalie;
van Baren, Nicolas;
Van den Eynde, Benoît J

Publication type:

Article

Kynurenine and uric acid levels in chronic myeloid leukemia patients.

Published in:

OncoImmunology, 2015, v. 4, n. 3, p. 00, doi. 10.4161/2162402X.2014.992646

By:

Vonka, Vladimir;
Humlova, Zuzana;
Klamova, Hana;
Kujovska-Krcmova, Lenka;
Petrackova, Martina;
Hamsikova, Eva;
Krmencikova-Fliegl, Monika;
Duskova, Martina;
Roth, Zdenek

Publication type:

Article

Indoleamine-2,3-dioxygenase (IDO) metabolic activity is detrimental for cervical cancer patient survival.

Published in:

OncoImmunology, 2015, v. 4, n. 2, p. N.PAG, doi. 10.4161/2162402X.2014.981457

By:

Ferns, Debbie M;
Jordanova, Ekaterina S;
Kenter, Gemma G;
Kema, Ido P;
Buist, Marrije R;
Nijman, Hans W

Publication type:

Article

Indoleamine 2,3-dioxygenase vaccination.

Published in:

OncoImmunology, 2015, v. 4, n. 1, p. N.PAG, doi. 10.4161/2162402X.2014.983770

By:

Andersen, Mads Hald;
Svane, Inge Marie

Publication type:

Article

Trial watch: IDO inhibitors in cancer therapy.

Published in:

OncoImmunology, 2014, v. 3, n. 10, p. N.PAG, doi. 10.4161/21624011.2014.957994

By:

Vacchelli, Erika;
Aranda, Fernando;
Eggermont, Alexander;
Sautès-Fridman, Catherine;
Tartour, Eric;
Kennedy, Eugene P;
Platten, Michael;
Zitvogel, Laurence;
Kroemer, Guido;
Galluzzi, Lorenzo

Publication type:

Article

A road less traveled paved by IDO silencing.

Published in:

OncoImmunology, 2013, v. 2, n. 3, p. e23322-1, doi. 10.4161/onci.23322

By:

Manuel, Edwin R.;
Diamond, Don J.

Publication type:

Article

Indoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer.

Published in:

OncoImmunology, 2013, v. 2, n. 3, p. e23428-1, doi. 10.4161/onci.23428

By:

Creelan, Ben C.;
Antonia, Scott;
Bepler, Gerold;
Garrett, Timothy J.;
Simon, George R.;
Soliman, Hatem H.

Publication type:

Article

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR A novel IDO effector pathway targeted by D-1-methyl-tryptophan.

Published in:

OncoImmunology, 2012, v. 1, n. 9, p. 1, doi. 10.4161/onci.21716

By:

Metz, Richard;
Rust, Sonja;
DuHadaway, James B.;
Mautino, Mario R.;
Munn, David H.;
Vahanian, Nicholas N.;
Link, Charles J.;
Prendergast, George C.

Publication type:

Article

Association of a functional Indoleamine 2,3-dioxygenase 2 genotype with specific immune responses.

Published in:

OncoImmunology, 2012, v. 1, n. 4, p. 441, doi. 10.4161/onci.19654

By:

Køllgaard, Tania;
Klausen, Tobias Wirenfeldt;
Idorn, Manja;
Holmgaard, Rikke Bæk;
thor Straten, Per;
Andersen, Mads Hald

Publication type:

Article

Impact of Indoleamine 2,3-Dioxygenase Enzyme Activity in Neuroendocrine Tumors.

Published in:

Neuroendocrinology, 2025, v. 115, n. 5, p. 411, doi. 10.1159/000543658

By:

Mancini, Camilla;
Pecora, Giulia;
Salerno, Gerardo;
Lionetto, Luana;
De Bernardini, Donatella;
Costanzi, Giuseppe;
Gabrielli, Saverio;
Veroli, Domenico;
Visco, Vincenzo;
Simmaco, Maurizio;
Zamponi, Virginia;
Mazzilli, Rossella;
Faggiano, Antongiulio

Publication type:

Article

Synthesis and evaluation of 1-methyl-D-Trp-[<sup>18</sup>F]BF<sub>3</sub>: a novel tryptophan derivative radiotracer for PET imaging.

Published in:

Journal of Radioanalytical & Nuclear Chemistry, 2025, v. 334, n. 5, p. 3111, doi. 10.1007/s10967-025-10107-0

By:

Wang, Guolin;
Zhang, Jiawei;
Su, Xinhui;
Xu, Qianhe;
Chen, Donghe;
Zhang, Qian;
Liu, Zhenfeng

Publication type:

Article

Inflammation and Prediction of Death in Type 2 Diabetes. Evidence of an Intertwined Link With Tryptophan Metabolism Open Access.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 5, p. e1323, doi. 10.1210/clinem/dgae593

By:

Menzaghi, Claudia;
Marucci, Antonella;
Mastroianno, Mario;
Ciaccia, Giulio Di;
Armillotta, Maria Pia;
Prehn, Cornelia;
Salvemini, Lucia;
Mangiacotti, Davide;
Adamski, Jerzy;
Fontana, Andrea;
Cosmo, Salvatore De;
Lamacchia, Olga;
Copetti, Massimiliano;
Trischitta, Vincenzo

Publication type:

Article

Elevated serum levels of kynurenine pathway metabolites in patients with Behçet disease.

Published in:

Amino Acids, 2022, v. 54, n. 6, p. 877, doi. 10.1007/s00726-022-03170-4

By:

Eryavuz Onmaz, Duygu;
Tezcan, Dilek;
Abusoglu, Sedat;
Sivrikaya, Abdullah;
Kuzu, Menekse;
Yerlikaya, Fatma Humeyra;
Yilmaz, Sema;
Unlu, Ali

Publication type:

Article

Inhibition of antigen-specific immune responses by co-application of an indoleamine 2,3-dioxygenase (IDO)-encoding vector requires antigen transgene expression focused on dendritic cells.

Published in:

Amino Acids, 2020, v. 52, n. 3, p. 411, doi. 10.1007/s00726-020-02817-4

By:

Sudowe, Stephan;
Höhn, Yvonne;
Renzing, Andrea;
Maxeiner, Joachim;
Montermann, Evelyn;
Habermeier, Alice;
Closs, Ellen;
Bros, Matthias;
Reske-Kunz, Angelika B.

Publication type:

Article

Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1.

Published in:

Amino Acids, 2014, v. 46, n. 9, p. 2155, doi. 10.1007/s00726-014-1766-3

By:

Pantouris, Georgios;
Serys, Martynas;
Yuasa, Hajime;
Ball, Helen;
Mowat, Christopher

Publication type:

Article

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease.

Published in:

Amino Acids, 2013, v. 45, n. 6, p. 1319, doi. 10.1007/s00726-013-1602-1

By:

Fatokun, Amos A.;
Hunt, Nicholas H.;
Ball, Helen J.

Publication type:

Article

Influence of inflammation on tryptophan metabolism in chronic rheumatic diseases: the role of the kynurenine pathway in an interferon-dependent mechanism in systemic lupus erythematosus and primary Sjögren's syndrome -- a literature review.

Published in:

Rheumatology Forum, 2024, v. 10, n. 1, p. 17, doi. 10.5603/rf.97738

By:

Witoszyńska-Sobkowiak, Joanna;
Sikorska, Dorota;
Samborski, Włodzimierz

Publication type:

Article

Tryptophan metabolism via the kynurenine pathway in selected rheumatic diseases: A review of the literature.

Published in:

Rheumatology Forum, 2023, v. 9, n. 1, p. 3, doi. 10.5603/RF.2023.0002

By:

Witoszyńska-Sobkowiak, Joanna;
Sikorska, Dorota;
Samborski, Włodzimierz

Publication type:

Article

Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients.

Published in:

Hereditas, 2022, v. 159, n. 1, p. 1, doi. 10.1186/s41065-022-00219-y

By:

Cao, Tingming;
Dai, Guangming;
Chu, Hongqian;
Kong, Chengcheng;
Duan, Huijuan;
Tian, Na;
Sun, Zhaogang

Publication type:

Article

Correction: Inhibitory effect of human indoleamine 2,3-dioxygenase 1 (hIDO1) by kazinols of 1,3-diphenylpropane derivatives.

Published in:

2024

By:

Oh, Taehoon;
Jung, Sunin;
Oh, Seon Min;
Park, Mi Hyeon;
Kim, Hyoung-Geun;
Lee, Su-Yeon;
Ko, Sung-Kyun;
Ryu, Hyung Won

Publication type:

Correction Notice

Inhibitory effect of human indoleamine 2,3-dioxygenase 1 (hIDO1) by kazinols of 1,3-diphenylpropane derivatives.

Published in:

Applied Biological Chemistry, 2024, v. 67, n. 1, p. 1, doi. 10.1186/s13765-024-00923-5

By:

Oh, Taehoon;
Jung, Sunin;
Oh, Seon Min;
Park, Mi Hyeon;
Kim, Hyoung-Geun;
Lee, Su-Yeon;
Ko, Sung-Kyun;
Ryu, Hyung Won

Publication type:

Article

Inhibitory effect of human indoleamine 2,3-dioxygenase 1 (hIDO1) by kazinols of 1,3-diphenylpropane derivatives.

Published in:

Applied Biological Chemistry, 2024, v. 67, n. 1, p. 1, doi. 10.1186/s13765-024-00923-5

By:

Oh, Taehoon;
Jung, Sunin;
Oh, Seon Min;
Park, Mi Hyeon;
Kim, Hyoung-Geun;
Lee, Su-Yeon;
Ko, Sung-Kyun;
Ryu, Hyung Won

Publication type:

Article

The antioxidant/anti‐inflammatory protective effects of rutin against ethanol‐induced testicular perturbation in rats: Involvement of the immunosuppressive indoleamine 2,3‐dioxygenase.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 3, p. 254, doi. 10.1111/bcpt.13919

By:

Ebokaiwe, Azubuike Peter;
Obasi, Doris Olachi;
Osawe, Sharon Oluchi;
Njoku, Rex Clovis C.

Publication type:

Article

Mediating the death of dormant tumor cells.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 4, p. 1, doi. 10.1080/23723556.2018.1458013

By:

Liu, Yuying;
Lv, Jiadi;
Huang, Bo

Publication type:

Article

Gene silencing of indoleamine 2,3-dioxygenase 1 inhibits lung cancer growth by suppressing T-cell exhaustion.

Published in:

Oncology Letters, 2020, v. 19, n. 6, p. 3827, doi. 10.3892/ol.2020.11477

By:

KE SHANG;
ZHIGANG WANG;
YINYING HU;
YANQIN HUANG;
KENG YUAN;
YANRONG YU

Publication type:

Article

Potential role of indoleamine 2,3-dioxygenase in primary biliary cirrhosis.

Published in:

Oncology Letters, 2017, v. 14, n. 5, p. 5497, doi. 10.3892/ol.2017.6834

By:

ASGHAR, KASHIF;
BRAIN, JOHN;
PALMER, JEREMY M.;
DOUGLASS, STEPHEN;
NAEMI, FATMAH M. A.;
O'BOYLE, GRAEME;
KIRBY, JOHN;
ALI, SIMI

Publication type:

Article

New aspects of activin biology in epididymal function and immunopathology.

Published in:

Andrology, 2024, v. 12, n. 5, p. 964, doi. 10.1111/andr.13523

By:

Wijayarathna, Rukmali;
Hedger, Mark P.

Publication type:

Article

Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 6, p. 334, doi. 10.3390/metabo14060334

By:

Stieger, Andrea;
Huber, Markus;
Yu, Zhanru;
Kessler, Benedikt M.;
Fischer, Roman;
Andereggen, Lukas;
Kobel, Beatrice;
Stueber, Frank;
Luedi, Markus M.;
Filipovic, Mark G.

Publication type:

Article

Identification of Genetic Markers Linked to The Activity of Indoleamine 2,3-Dioxygenase and Kidney Function.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 4, p. 541, doi. 10.3390/metabo13040541

By:

Kim, Hye-Rim;
Jin, Hyun-Seok;
Eom, Yong-Bin

Publication type:

Article

Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD.

Published in:

Metabolites (2218-1989), 2019, v. 9, n. 10, p. 212, doi. 10.3390/metabo9100212

By:

Naz, Shama;
Bhat, Maria;
Ståhl, Sara;
Forsslund, Helena;
Sköld, C. Magnus;
Wheelock, Åsa M.;
Wheelock, Craig E.

Publication type:

Article

Enhanced Expression of Indoleamine 2,3-Dioxygenase in Helicobacter pylori-Infected Human Gastric Mucosa Modulates Th1/Th2 Pathway and Interleukin 17 Production.

Published in:

Helicobacter, 2015, v. 20, n. 1, p. 41, doi. 10.1111/hel.12174

By:

Larussa, Tiziana;
Leone, Isabella;
Suraci, Evelina;
Nazionale, Immacolata;
Procopio, Teresa;
Conforti, Francesco;
Abenavoli, Ludovico;
Hribal, Marta L.;
Imeneo, Maria;
Luzza, Francesco

Publication type:

Article

Discovery of Icotinib-1,2,3-Triazole Derivatives as IDO1 Inhibitors.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.579024

By:

Mao, Long-fei;
Wang, Yu-wei;
Zhao, Jie;
Xu, Gui-qing;
Yao, Xiao-jun;
Li, Yue-Ming

Publication type:

Article

The Immunomodulator 1-Methyltryptophan Drives Tryptophan Catabolism Toward the Kynurenic Acid Branch.

Published in:

Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.00313

By:

Wirthgen, Elisa;
Leonard, Anne K.;
Scharf, Christian;
Domanska, Grazyna

Publication type:

Article

Inflammation-Induced Tryptophan Breakdown is Related With Anemia, Fatigue, and Depression in Cancer.

Published in:

Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.00249

By:

Lanser, Lukas;
Kink, Patricia;
Egger, Eva Maria;
Willenbacher, Wolfgang;
Fuchs, Dietmar;
Weiss, Guenter;
Kurz, Katharina

Publication type:

Article

Polarization of Human Monocyte-Derived Cells With Vitamin D Promotes Control of Mycobacterium tuberculosis Infection.

Published in:

Frontiers in Immunology, 2020, v. 10, p. 1, doi. 10.3389/fimmu.2019.03157

By:

Rao Muvva, Jagadeeswara;
Parasa, Venkata Ramanarao;
Lerm, Maria;
Svensson, Mattias;
Brighenti, Susanna

Publication type:

Article

Tryptophan Dietary Impacts Gut Barrier and Metabolic Diseases.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02113

By:

Taleb, Soraya

Publication type:

Article

Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02017

By:

Davison, Laura M.;
Liu, Jessica C.;
Huang, Lei;
Carroll, Thomas M.;
Mellor, Andrew L.;
Jørgensen, Trine N.

Publication type:

Article

Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01973

By:

Gargaro, Marco;
Vacca, Carmine;
Massari, Serena;
Scalisi, Giulia;
Manni, Giorgia;
Mondanelli, Giada;
Mazza, Emilia M. C.;
Bicciato, Silvio;
Pallotta, Maria T.;
Orabona, Ciriana;
Belladonna, Maria L.;
Volpi, Claudia;
Bianchi, Roberta;
Matino, Davide;
Iacono, Alberta;
Panfili, Eleonora;
Proietti, Elisa;
Iamandii, Ioana Maria;
Cecchetti, Violetta;
Puccetti, Paolo

Publication type:

Article

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00925

By:

Vigano, Selena;
Alatzoglou, Dimitrios;
Irving, Melita;
Ménétrier-Caux, Christine;
Caux, Christophe;
Romero, Pedro;
Coukos, George

Publication type:

Article

Durable Clinical Responses and Long-Term Follow-Up of Stage III–IV Non-Small-Cell Lung Cancer (NSCLC) Patients Treated With IDO Peptide Vaccine in a Phase I Study—A Brief Research Report.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02145

By:

Kjeldsen, Julie Westerlin;
Iversen, Trine Zeeberg;
Engell-Noerregaard, Lotte;
Mellemgaard, Anders;
Andersen, Mads Hald;
Svane, Inge Marie

Publication type:

Article

Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection.

Published in:

Journal of Gastroenterology, 2013, v. 48, n. 5, p. 660, doi. 10.1007/s00535-012-0667-z

By:

Higashitani, Koyo;
Kanto, Tatsuya;
Kuroda, Shoko;
Yoshio, Sachiyo;
Matsubara, Tokuhiro;
Kakita, Naruyasu;
Oze, Tsugiko;
Miyazaki, Masanori;
Sakakibara, Mitsuru;
Hiramatsu, Naoki;
Mita, Eiji;
Imai, Yasuharu;
Kasahara, Akinori;
Okuno, Alato;
Takikawa, Osamu;
Hayashi, Norio;
Takehara, Tetsuo

Publication type:

Article

Human chorionic gonadotropin and indolamine 2,3-dioxygenase in patients with GVHD.

Published in:

Bone Marrow Transplantation, 2014, v. 49, n. 6, p. 800, doi. 10.1038/bmt.2014.59

By:

Elmaagacli, A H;
Ditschkowski, M;
Steckel, N K;
Gromke, T;
Ottinger, H;
Hillen, U;
Baba, H A;
Trenschel, R;
Beelen, D W;
Koldehoff, M

Publication type:

Article

Inducible Expression of Indoleamine 2,3-Dioxygenase Attenuates Acute Rejection of Tissue-Engineered Lung Allografts in Rats.

Published in:

2016

By:

Ebrahimi, A.;
Sadroddini, E.;
Khorramizadeh, M. R.;
Kardar, G. A.;
Toolabi, L. Teimoori;
Ghanbari, H.

Publication type:

Abstract

Regulation of serotonin production by specific microbes from piglet gut.

Published in:

Journal of Animal Science & Biotechnology, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s40104-023-00903-7

By:

Liu, Ziyu;
Ling, Yidan;
Peng, Yu;
Han, Shuibing;
Ren, Yuting;
Jing, Yujia;
Fan, Wenlu;
Su, Yong;
Mu, Chunlong;
Zhu, Weiyun

Publication type:

Article

Immune Landscape of Thyroid Cancers: New Insights.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.637826

By:

Menicali, Elisa;
Guzzetti, Martina;
Morelli, Silvia;
Moretti, Sonia;
Puxeddu, Efisio

Publication type:

Article

Expression and Clinical Significance of Various Checkpoint Molecules in Advanced Osteosarcoma: Possibilities for Novel Immunotherapy.

Published in:

Orthopaedic Surgery, 2023, v. 15, n. 3, p. 829, doi. 10.1111/os.13620

By:

Xie, Lu;
Chen, Chenglong;
Liang, Xin;
Xu, Jie;
Sun, Xin;
Sun, Kunkun;
Yang, Rongli;
Tang, Xiaodong;
Guo, Wei

Publication type:

Article

Metabolite Genome-Wide Association Study for Indoleamine 2,3-Dioxygenase Activity Associated with Chronic Kidney Disease.

Published in:

Genes, 2021, v. 12, n. 12, p. 1905, doi. 10.3390/genes12121905

By:

Kim, Hye-Rim;
Jin, Hyun-Seok;
Eom, Yong-Bin

Publication type:

Article

Tryptophan Depletion Modulates Tryptophanyl-tRNA Synthetase-Mediated High-Affinity Tryptophan Uptake into Human Cells.

Published in:

Genes, 2020, v. 11, n. 12, p. 1423, doi. 10.3390/genes11121423

By:

Yokosawa, Takumi;
Sato, Aomi;
Wakasugi, Keisuke

Publication type:

Article

Gene Expression of Indoleamine 2,3 Dioxygenase 1, Insulin-Growth Factor 1 and Red/IK Cytokine in Alopecia Areata.

Published in:

Notulae Scientia Biologicae, 2014, v. 6, n. 3, p. 263

By:

ŞENILĂ, Simona;
BĂLĂCESCU, Ovidiu;
BĂLĂCESCU, Loredana;
CANDREA, Elisabeta;
UNGUREANU, Loredana;
DĂNESCU, Sorina;
COSGAREA, Rodica

Publication type:

Article

Evaluation of Indoleamine 2,3-Dioxygenase (IDO) Expression in Osteosarcoma: Insights From a 10-Year Retrospective Cohort.

Published in:

OncoTargets & Therapy, 2025, v. 18, p. 367, doi. 10.2147/OTT.S494899

By:

Farooq, Asim;
Amin, Aatif;
Bashir, Shaarif;
Fatima, Merium;
Hassan, Muhammad;
Sheikh, Ali Zafar;
Tahseen, Muhammad;
Sheikh, Umer Nisar;
Asghar, Kashif

Publication type:

Article