Works about INDIRUBIN

Results: 56

Characterization of a flavin-containing monooxygenase from Corynebacterium glutamicum and its application to production of indigo and indirubin.

Published in:

Biotechnology Letters, 2015, v. 37, n. 8, p. 1637, doi. 10.1007/s10529-015-1824-2

By:

Ameria, Sisi;
Jung, Hye;
Kim, Hee;
Han, Sang;
Kim, Hak;
Lee, Jin

Publication type:

Article

In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems.

Published in:

Journal of Pharmacy & Pharmacology, 2014, v. 66, n. 11, p. 1567, doi. 10.1111/jphp.12286

By:

Heshmati, Nasim;
Cheng, Xinlai;
Dapat, Else;
Sassene, Philip;
Eisenbrand, Gerhard;
Fricker, Gert;
Müllertz, Anette

Publication type:

Article

Indirubin derivatives are potent and selective anti-Trypanosoma cruzi agents.

Published in:

Virulence, 2018, v. 9, n. 1, p. 1658, doi. 10.1080/21505594.2018.1532242

By:

Efstathiou, Antonia;
Meira, Cássio Santana;
Gaboriaud-Kolar, Nicolas;
Bastos, Tanira Matutino;
Rocha, Vinícius Pinto Costa;
Vougogiannopoulou, Konstantina;
Skaltsounis, Alexios-Leandros;
Smirlis, Despina;
Soares, Milena Botelho Pereira

Publication type:

Article

Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling

Published in:

Molecular Oncology, 2012, v. 6, n. 3, p. 276, doi. 10.1016/j.molonc.2012.02.002

By:

Nam, Sangkil;
Scuto, Anna;
Yang, Fan;
Chen, WenYong;
Park, Sungman;
Yoo, Hwa-Seung;
Konig, Heiko;
Bhatia, Ravi;
Cheng, Xinlai;
Merz, Karl-Heinz;
Eisenbrand, Gerhard;
Jove, Richard

Publication type:

Article

Induction of atypical cell death in thyroid carcinoma cells by the indirubin derivative 7-bromoindirubin-3'-oxime (7BIO).

Published in:

Cancer Cell International, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12935-015-0251-8

By:

Broecker-Preuss, Martina;
Becher-Boveleth, Nina;
Gall, Susanne;
Rehmann, Katrin;
Schenke, Susann;
Mann, Klaus

Publication type:

Article

E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling.

Published in:

Journal of Neuro-Oncology, 2015, v. 125, n. 2, p. 265, doi. 10.1007/s11060-015-1917-8

By:

Zhang, Yanmin;
Du, Zhaoxiao;
Zhuang, Zirong;
Wang, Yanjun;
Wang, Fen;
Liu, Shuai;
Wang, Han;
Feng, Hairong;
Li, Haoyuan;
Wang, Liyan;
Zhang, Xianghong;
Hao, Aijun

Publication type:

Article

Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC.

Published in:

Molecules, 2017, v. 22, n. 9, p. 1546, doi. 10.3390/molecules22091546

By:

Tegethoff, Jana;
Bischoff, Roland;
Saleh, Sawsan;
Blagojevic, Biljana;
Merz, Karl-Heinz;
Xinlai Cheng

Publication type:

Article

Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo.

Published in:

Archives of Toxicology, 2008, v. 82, n. 1, p. 5, doi. 10.1007/s00204-007-0232-3

By:

Sugihara, Kazumi;
Okayama, Takashige;
Kitamura, Shigeyuki;
Yamashita, Keisuke;
Yasuda, Mineo;
Miyairi, Shinichi;
Minobe, Yasushi;
Ohta, Shigeru

Publication type:

Article

Indirubin-3-monoxime exhibits anti-inflammatory properties by down-regulating NF-κB and JNK signaling pathways in lipopolysaccharide-treated RAW264.7 cells.

Published in:

Inflammation Research, 2012, v. 61, n. 4, p. 319, doi. 10.1007/s00011-011-0413-7

By:

Kim, Jin-Kyung;
Park, Geun-Mook

Publication type:

Article

A traditional Chinese remedy points to a natural skin habitat: indirubin (indigo naturalis) for psoriasis and the Malassezia metabolome.

Published in:

2018

By:

Gaitanis, G.;
Magiatis, P.;
Velegraki, A.;
Bassukas, I. D.

Publication type:

Letter to the Editor

Comparison of indirubin concentrations in indigo naturalis ointment for psoriasis treatment: a randomized, double‐blind, dosage‐controlled trial.

Published in:

British Journal of Dermatology, 2018, v. 178, n. 1, p. e85, doi. 10.1111/bjd.15894

By:

Lin, Y.‐K.;
See, L.‐C.;
Huang, Y.‐H.;
Chi, C.‐C.;
Hui, R.C.‐Y.

Publication type:

Article

Indirubin: a novel topical agent in the treatment of psoriasis.

Published in:

British Journal of Dermatology, 2018, v. 178, n. 1, p. 21, doi. 10.1111/bjd.16074

By:

Sekhon, S.;
Koo, J.

Publication type:

Article

Comparison of indirubin concentrations in indigo naturalis ointment for psoriasis treatment: a randomized, double‐blind, dosage‐controlled trial.

Published in:

British Journal of Dermatology, 2018, v. 178, n. 1, p. 124, doi. 10.1111/bjd.15894

By:

Lin, Y.‐K.;
See, L.‐C.;
Huang, Y.‐H.;
Chi, C.‐C.;
Hui, R.C.‐Y.

Publication type:

Article

The Degradation of Indigo Sodium Disulphonate by Chromium Isomorphic Replacement in Magnetite.

Published in:

Journal of the Chinese Chemical Society, 2016, v. 63, n. 7, p. 611, doi. 10.1002/jccs.201500527

By:

Zhou, Lianghua;
Chu, Benli;
He, Songhua;
Yu, Jiayuan;
Lin, Xiaoju;
Wang, Aili

Publication type:

Article

Purple Urine Bag Syndrome- An Alarming Situation.

Published in:

2016

By:

FARIDI, M. S.;
RAHMAN, JAWAID;
MIBANG, NALOH;
SHANTAJIT, N.;
SOMARENDRA, KHUMUKCHUM

Publication type:

Case Study

An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase-3.

Published in:

Parasites & Vectors, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-3305-7-234

By:

Efstathiou, Antonia;
Gaboriaud-Kolar, Nicolas;
Smirlis, Despina;
Myrianthopoulos, Vassilios;
Vougogiannopoulou, Konstantina;
Alexandratos, Alexandros;
Kritsanida, Marina;
Mikros, Emmanuel;
Soteriadou, Ketty;
Skaltsounis, Alexios-Leandros

Publication type:

Article

CORDYCEPIN AND CORDYCEPS SINENSIS REDUCE THE GROWTH OF HUMAN PROMYELOCYTIC LEUKAEMIA CELLS THROUGH THE Wnt SIGNALLING PATHWAY.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2007, v. 34, p. S61, doi. 10.1111/j.1440-1681.2007.04781.x

By:

Yoshikawa, Noriko;
Nakamura, Kazuki;
Yamaguchi, Yu;
Kagota, Satomi;
Shinozuka, Kazumasa;
Kunitomo, Masaru

Publication type:

Article

Identification of three species commonly known as "daqingye" by internal leaf anatomy and high-performance liquid chromatography analyses.

Published in:

Acta Societatis Botanicorum Poloniae, 2018, v. 87, n. 1, p. 1, doi. 10.5586/asbp.3575

By:

Yingjiao Zhang;
Yongqing Zhu;
Jian Chen;
Chen Xia;
Junling Deng;
Huajia Li;
Yanling Li;
Juan Li;
Pei Liu

Publication type:

Article

The combination of indirubin and isatin attenuates dextran sodium sulfate induced ulcerative colitis in mice.

Published in:

Biochemistry & Cell Biology, 2018, v. 96, n. 5, p. 636, doi. 10.1139/bcb-2018-0041

By:

Gao, Wenyan;
Zhang, Luding;
Wang, Xiaoqian;
Yu, Li;
Wang, Changhong;
Gong, Yang

Publication type:

Article

Inhibition of Suicidal Erythrocyte Death by Indirubin-3'-Monoxime.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 45, n. 3, p. 1108, doi. 10.1159/000487352

By:

Chunqiu Liu;
Peipei Jiang;
Yuanhong Xu;
Meijuan Zheng;
Jinpin Qiao;
Xueyong Zhou;
Dake Huang;
Maohong Bian

Publication type:

Article

Inhibition of Suicidal Erythrocyte Death by Indirubin-3’-Monoxime.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 45, n. 3, p. 1108, doi. 10.1159/000487352

By:

Liu, Chunqiu;
Jiang, Peipei;
Xu, Yuanhong;
Zheng, Meijuan;
Qiao, Jinpin;
Zhou, Xueyong;
Huang, Dake;
Bian, Maohong

Publication type:

Article

Preparation and investigation of indirubin‐loaded SLN nanoparticles and their anti‐cancer effects on human glioblastoma U87MG cells.

Published in:

Cell Biology International, 2019, v. 43, n. 1, p. 2, doi. 10.1002/cbin.11037

By:

Rahiminejad, Ali;
Rashti, Ali;
Khosravani, Masood;
Dinarvand, Rassoul;
Johari, Behrooz;
Nodooshan, Saeedeh Jafari;
Rismani, Elham;
Saltanatpour, Zohreh;
Raigani, Mozhgan;
Mahdaviani, Parvin;
Rahiminejad, Sajad

Publication type:

Article

DFT study of the effect of substituents on the absorption and emission spectra of Indigo.

Published in:

Chemistry Central Journal, 2012, v. 6, n. 1, p. 70, doi. 10.1186/1752-153X-6-70

By:

Cervantes-Navarro, Francisco;
Glossman-Mitnik, Daniel

Publication type:

Article

The development of indigo reduction methods and pre-reduced indigo products.

Published in:

Coloration Technology, 2009, v. 125, n. 4, p. 193, doi. 10.1111/j.1478-4408.2009.00197.x

By:

Blackburn, Richard S;
Bechtold, Thomas;
John, Philip

Publication type:

Article

Synergistic action of laccases from Trametes hirsuta Bm2 improves decolourization of indigo carmine.

Published in:

Letters in Applied Microbiology, 2015, v. 61, n. 3, p. 252, doi. 10.1111/lam.12451

By:

Zapata‐Castillo, P.;
Villalonga‐Santana, L.;
Islas‐Flores, I.;
Rivera‐Muñoz, G.;
Ancona‐Escalante, W.;
Solís‐Pereira, S.

Publication type:

Article

Preconcentration of Indigotin and Indirubin from Indigowoad Roots with Novel Quinoline Ionic Liquids with Determination by High-Performance Liquid Chromatography.

Published in:

Analytical Letters, 2015, v. 48, n. 8, p. 1257, doi. 10.1080/00032719.2014.981822

By:

Nie, Lirong;
Wang, Litao;
Song, Hang;
Chen, Chen;
Yao, Shun

Publication type:

Article

Indirubin-pregnane X receptor-JNK axis accelerates skin wound healing.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-54754-2

By:

Tanaka, Yuka;
Uchi, Hiroshi;
Ito, Takamichi;
Furue, Masutaka

Publication type:

Article

Impact of binding site waters on inhibitor design: contemplating a novel inverse binding mode of indirubin derivatives in DYRK kinases.

Published in:

2014

By:

Cappel, Daniel;
Myrianthopoulos, Vassilios;
Mikros, Emmanuel;
Sherman, Woody

Publication type:

Abstract

Targeting of CDK9 with indirubin 3’-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183425

By:

Medina-Moreno, Sandra;
Dowling, Thomas C.;
Zapata, Juan C.;
Le, Nhut M.;
Sausville, Edward;
Bryant, Joseph;
Redfield, Robert R.;
Heredia, Alonso

Publication type:

Article

Indirubin-3′-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration.

Published in:

Cardiovascular Research, 2014, v. 101, n. 3, p. 522

By:

Blažević, Tina;
Schaible, Anja M.;
Weinhäupl, Katharina;
Schachner, Daniel;
Nikels, Felix;
Weinigel, Christina;
Barz, Dagmar;
Atanasov, Atanas G.;
Pergola, Carlo;
Werz, Oliver;
Dirsch, Verena M.;
Heiss, Elke H.

Publication type:

Article

Indirubin inhibits the migration, invasion, and activation of fibroblast-like synoviocytes from rheumatoid arthritis patients.

Published in:

Inflammation Research, 2017, v. 66, n. 5, p. 433, doi. 10.1007/s00011-017-1027-5

By:

Huang, Mingcheng;
Wang, Lihui;
Zeng, Shan;
Qiu, Qian;
Zou, Yaoyao;
Shi, Maohua;
Xu, Hanshi;
Liang, Liuqin

Publication type:

Article

Effects of Eighteen 7-Nitrogen Substituted Indirubin Derivatives on the Proliferation of Six Cancer Cell Lines.

Published in:: Natural Product Research & Development, 2010, v. 22, n. 5, p. 899
Publication type:: Article

Effect on Active Components by Waterlog of Roots of Isatis indigotica.

Published in:

Natural Product Research & Development, 2009, v. 21, n. 5, p. 832

By:

TANG Xiao-qing;
WANG Kang-cai;
WEN Jian-yun

Publication type:

Article

Key Role of Reactive Oxygen Species (ROS) in Indirubin Derivative-Induced Cell Death in Cutaneous T-Cell Lymphoma Cells.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1158, doi. 10.3390/ijms20051158

By:

Soltan, Marwa Y.;
Sumarni, Uly;
Assaf, Chalid;
Langer, Peter;
Reidel, Ulrich;
Eberle, Jürgen

Publication type:

Article

Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2692, doi. 10.3390/ijms19092692

By:

Faber, Samantha C.;
Soshilov, Anatoly A.;
Giani Tagliabue, Sara;
Bonati, Laura;
Denison, Michael S.

Publication type:

Article

Cytometrical analysis of the adverse effects of indican, indoxyl, indigo, and indirubin on rat thymic lymphocytes.

Published in:

Toxicology Research, 2018, v. 7, n. 3, p. 513, doi. 10.1039/c7tx00244k

By:

Funakoshi, Yurie;
Azuma, Ayako;
Ishikawa, Mizuki;
Itsuki, Satoru;
Tamura, Yasuaki;
Kanemaru, Kaori;
Hirai, Shogo;
Oyama, Yasuo

Publication type:

Article

Indirubin and NAD+ prevent mitochondrial ischaemia/reperfusion damage in fatty livers.

Published in:

European Journal of Clinical Investigation, 2018, v. 48, n. 6, p. 1, doi. 10.1111/eci.12932

By:

Teodoro, João Soeiro;
Varela, Ana Teresa;
Duarte, Filipe Valente;
Gomes, Ana Patrícia;
Palmeira, Carlos Marques;
Rolo, Anabela Pinto

Publication type:

Article

Indirubin-3-Oxime Prevents HO-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway.

Published in:

Cellular & Molecular Neurobiology, 2017, v. 37, n. 4, p. 655, doi. 10.1007/s10571-016-0402-z

By:

Yu, Jie;
Zheng, Jiacheng;
Lin, Jiajia;
Jin, Linlu;
Yu, Rui;
Mak, Shinghung;
Hu, Shengquan;
Sun, Hongya;
Wu, Xiang;
Zhang, Zaijun;
Lee, Mingyuen;
Tsim, Wahkeung;
Su, Wei;
Zhou, Wenhua;
Cui, Wei;
Han, Yifan;
Wang, Qinwen

Publication type:

Article

Indirubin-3′-Oxime Reverses Bone Loss in Ovariectomized and Hindlimb-Unloaded Mice Via Activation of the Wnt/β-Catenin Signaling.

Published in:

Journal of Bone & Mineral Research, 2014, v. 29, n. 5, p. 1196, doi. 10.1002/jbmr.2147

By:

Zahoor, Muhammad;
Cha, Pu-Hyeon;
Min, Do Sik;
Choi, Kang-Yell

Publication type:

Article

Improved Synthesis of Indirubin Derivatives by Sequential Build-Up of the Indoxyl Unit: First Preparation of Fluorescent Indirubins.

Published in:

Helvetica Chimica Acta, 2012, v. 95, n. 8, p. 1461, doi. 10.1002/hlca.201200042

By:

Riepl, Herbert M.;
Urmann, Corinna

Publication type:

Article

Antiherpetic potential of 6-bromoindirubin-3′-acetoxime (BIO-acetoxime) in human oral epithelial cells.

Published in:

Archives of Virology, 2013, v. 158, n. 6, p. 1287, doi. 10.1007/s00705-013-1629-3

By:

Hsu, Mei-Ju;
Hung, Shan-Ling

Publication type:

Article

Indirubin, a Constituent of the Chinese Herbal Medicine Qing-Dai, Attenuates Dextran Sulfate Sodium-induced Murine Colitis.

Published in:

Yonago Acta Medica, 2018, v. 61, n. 2, p. 128, doi. 10.33160/yam.2018.06.005

By:

Naruo Tokuyasu;
Kohei Shomori;
Kuniki Amano;
Soichiro Honjo;
Teruhisa Sakamoto;
Joji Watanabe;
Masataka Amisaki;
Masaki Morimoto;
Ei Uchinaka;
Takuki Yagyu;
Hiroaki Saito;
Hisao Ito;
Yoshiyuki Fujiwara

Publication type:

Article

Indirubin inhibits cell proliferation, migration, invasion and angiogenesis in tumor-derived endothelial cells.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 2937, doi. 10.2147/OTT.S157949

By:

Li, Zhuohong;
Zhu, Chaofu;
An, Baiping;
Chen, Yu;
He, Xiuyun;
Qian, Lin;
Lan, Lan;
Li, Shijie

Publication type:

Article

Indirubin Increases CD4+CD25+Foxp3+ Regulatory T Cells to Prevent Immune Thrombocytopenia in Mice.

Published in:

PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0142634

By:

Zhang, Aijun;
Ning, Bin;
Sun, Nianzheng;
Wei, Jianlu;
Ju, Xiuli

Publication type:

Article

An Indirubin Derivative, Indirubin-3′-Monoxime Suppresses Oral Cancer Tumorigenesis through the Downregulation of Survivin.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0070198

By:

Lo, Wan-Yu;
Chang, Nai-Wen

Publication type:

Article

Synthesis of a Dual Functional Anti-MDR Tumor Agent PH II-7 with Elucidations of Anti-Tumor Effects and Mechanisms.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032782

By:

Ye Su;
Xin Cheng;
Yaohong Tan;
Yunhui Hu;
Yuan Zhou;
Juanni Liu;
Yuanfu Xu;
Yinliang Xie;
Caiyun Wang;
Yingdai Gao;
Jianxiang Wang;
Tao Cheng;
Chunzheng Yang;
Dongsheng Xiong;
Hua Miao

Publication type:

Article

Indirubin Derivative 7-Bromoindirubin-3-Oxime (7Bio) Attenuates Aβ Oligomer-Induced Cognitive Impairments in Mice.

Published in:

Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00393

By:

Liping Chen;
Chunhui Huang;
Jieyi Shentu;
Minjun Wang;
Sicheng Yan;
Fei Zhou;
Zaijun Zhang;
Chuang Wang;
Yifan Han;
Qinwen Wang;
Wei Cui

Publication type:

Article

Production of Indirubin from Tryptophan by Recombinant Escherichia coli Containing Naphthalene Dioxygenase Genes from Comamonas sp. MQ.

Published in:

Applied Biochemistry & Biotechnology, 2014, v. 172, n. 6, p. 3194, doi. 10.1007/s12010-014-0743-3

By:

Zhang, Xuwang;
Qu, Yuanyuan;
Ma, Qiao;
Kong, Chunlei;
Zhou, Hao;
Cao, Xiangyu;
Shen, Wenli;
Shen, E;
Zhou, Jiti

Publication type:

Article

Biotransformation of Indole to Indigo by the Whole Cells of Phenol Hydroxylase Engineered Strain in Biphasic Systems.

Published in:

Applied Biochemistry & Biotechnology, 2013, v. 169, n. 4, p. 1088, doi. 10.1007/s12010-012-0069-y

By:

Shi, Shengnan;
Ma, Fang;
Sun, Tieheng;
Li, Ang;
Zhou, Jiti;
Qu, Yuanyuan

Publication type:

Article

Dietary Ligands of the Aryl Hydrocarbon Receptor Induce Anti-Inflammatory and Immunoregulatory Effects on Murine Dendritic Cells.

Published in:

Toxicological Sciences, 2011, v. 124, n. 2, p. 327, doi. 10.1093/toxsci/kfr249

By:

Benson, Jenna M.;
Shepherd, David M.

Publication type:

Article