Works matching DE "IN vivo studies"

Results: 5000

Evaluation of FXR Activity in Pollutants Identified in Sewage Sludge and Subsequent in Vitro and in Vivo Characterization of Metabolic Effects of Triphenyl Phosphate.

Published in:

Environmental Health Perspectives, 2025, v. 133, n. 3, p. 047005-1, doi. 10.1289/EHP15435

By:

Yi Yang;
Ling Jiao;
Yixuan Huang;
Hailin Shang;
Enrui Li;
Hong Chang;
Hongyang Cui;
Yi Wan

Publication type:

Article

In vitro and in vivo antibacterial activity, resistance analysis and molecular docking study of pleuromutilin derivatives against Streptococcus suis.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2025, v. 80, n. 5, p. 1274, doi. 10.1093/jac/dkaf064

By:

Wu, Sujuan;
Zhang, Lu;
Luo, Xinyue;
Lin, Changcheng;
Wan, Peng;
Huang, Honghao;
Lu, Yixing;
Tang, Youzhi;
Zeng, Zhenling

Publication type:

Article

Comparative evaluation of remineralization potential of three commercially available toothpastes in children aged 7-12 years using DIAGNOdent Pen - A randomized control in-vivo study.

Published in:

Journal of Dental Specialities, 2025, v. 13, n. 1, p. 100, doi. 10.18231/j.jds.2025.015

By:

Jha, Aastha;
Kapoor, Rishabh;
Mathur, Shivani;
Choubey, Shikha;
Bhat, Diksha

Publication type:

Article

The effect of lactate dehydrogenase B and its mediated histone lactylation on chondrocyte ferroptosis during osteoarthritis.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05894-x

By:

Zhang, Yang;
Zhao, Chen-Yu;
Zhou, Zheng;
Li, Cheng-Cun;
Wang, Qiang

Publication type:

Article

LncRNA HCG18 regulates the progression of spinal tuberculosis by modulating the hsa-miR-146a-5p/TGF-β1/SMADs pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05810-3

By:

Li, Feng;
Tan, Hongdong;
Zhang, Xiao;
Zhao, Xiaodong;
Li, Xiaopeng;
Chen, Gaoyang

Publication type:

Article

Polyacrylamide Gel Calibration Phantoms for Quantification in Sodium MRI.

Published in:

NMR in Biomedicine, 2025, v. 38, n. 6, p. 1, doi. 10.1002/nbm.70056

By:

Rot, Samuel;
Oliver‐Taylor, Aaron;
Baker, Rebecca R.;
Steeden, Jennifer A.;
Golay, Xavier;
Solanky, Bhavana S.;
Gandini Wheeler‐Kingshott, Claudia A. M.

Publication type:

Article

Repurposing Nitroimidazoles: A New Frontier in Combatting Bacterial Virulence and Quorum Sensing via In Silico, In Vitro, and In Vivo Insights.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70101

By:

Khafagy, El‐Sayed;
Saqr, Ahmed Al;
Almutairy, Bjad K.;
Aldawsari, Mohammed F.;
Lila, Amr Selim Abu;
Ibrahim, Tarek S.;
Hegazy, Wael A. H.;
Salem, Ibrahim M.

Publication type:

Article

A novel acridine flow cytometry marker to track post‐transfusion amustaline/glutathione pathogen‐reduced red blood cell survival in sickle cell disease patients.

Published in:

Transfusion, 2025, v. 65, n. 5, p. 909, doi. 10.1111/trf.18245

By:

Benjamin, Richard J.;
Pitman, John P.;
Karim, Christopher;
Huang, Shengnan;
Erickson, Anna;
Corash, Laurence;
Mufti, Nina;
Roback, John D.;
Zerra, Patricia E.;
Fasano, Ross M.;
Yee, Marianne E. M.

Publication type:

Article

Pharmacokinetics of Dual Amino Acids for Dry Powder Inhalation Therapy in Pulmonary Drug Delivery: An In-Vivo Study.

Published in:

Addiction & Health, 2025, v. 17, p. 1, doi. 10.34172/ahj.1538

By:

Abinaya, Mani;
Mohan, Sellappan;
Nagarajan, Arumugam

Publication type:

Article

Knockdown of Galectin-3 confers myocardial protection against ischemia-reperfusion injury, modulating oxidative stress, inflammatory response, and the peroxisome proliferator-activated receptor g signaling pathway.

Published in:

CytoJournal, 2025, v. 22, p. 1, doi. 10.25259/Cytojournal_12_2025

By:

Chen, Duo;
Wen, Jingyu;
Zang, Wei;
Lin, Xuehong

Publication type:

Article

Neuroprotective, and memory enhancement effects of Salvia aristata and its phenolic constituents: an in vitro, and in vivo study.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04902-1

By:

Dabaghian, Farid;
Delnavazi, Mohammad-Reza;
Hariri, Roshanak;
Akbarzadeh, Tahmineh;
Tayarani-Najaran, Zahra;
Shams Ardekani, Mohammad Reza;
Sharifzadeh, Mohammad;
Khanavi, Mahnaz

Publication type:

Article

PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1537388

By:

Wei, Zhen;
Pan, Xiaodong;
Cui, Xiaoli;
Zhang, Jing;
Dai, Xiaoman;
Zeng, Yuqi;
Chen, Xiaochun

Publication type:

Article

Wenjing Zhitong Decoction Alleviates Primary Dysmenorrhea Mediated by Pain Sensitization Via the ERα‐BDNF Signaling Pathway.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2025, v. 2025, p. 1, doi. 10.1155/jcpt/5516416

By:

Qin, Yajie;
Yang, Xiaotian;
Tang, Xingran;
Zhao, Huijin;
Zhou, Huifang;
Chauhan, Anjali

Publication type:

Article

Exploring the Antiemetic Potential of Caffeic Acid: A Combined In Vivo and Computational Approach.

Published in:

Neurogastroenterology & Motility, 2025, v. 37, n. 6, p. 1, doi. 10.1111/nmo.70003

By:

Bhuia, Md. Shimul;
Ferdous, Jannatul;
Chowdhury, Raihan;
Ansari, Siddique Akber;
Ansari, Irfan Aamer;
Al Hasan, Md. Sakib;
Sheikh, Salehin;
Islam, Muhammad Torequl

Publication type:

Article

Amyloid-beta peptide toxicity in the aged brain is a one-way journey into Alzheimer's disease.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1569181

By:

Culley, Georgia;
Henriques, Alexandre;
Hardy, Delphine;
Wojcinski, Alexandre;
Chabert, Adrien;
El Waly, Bilal;
Poindron, Philippe;
Callizot, Noelle

Publication type:

Article

Design, optimization, and ADMET evaluation of S11a-0000168202: A promising LIMK1 inhibitor for gastric cancer treatment.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323699

By:

Li, Guojun;
Chen, Jionghuang;
Chen, Rui;
Yu, Weihua

Publication type:

Article

Phytoactives for Obesity Management: Integrating Nanomedicine for Its Effective Delivery.

Published in:

Nutrition Reviews, 2025, v. 83, n. 6, p. 1152, doi. 10.1093/nutrit/nuae136

By:

Mandal, Ashok Kumar;
Sahoo, Ankit;
Almalki, Waleed H;
Almujri, Salem Salman;
Alhamyani, Abdulrahman;
Aodah, Alhussain;
Alruwaili, Nabil K;
Kadir, Sharifah Zamiah Binti Syed Abdul;
Mandal, Rambha Kumari;
Almalki, Rami A;
Lal, Jonathan A;
Rahman, Mahfoozur

Publication type:

Article

Ganoderma Lucidum Extract: a Triple-action Solution for Sensitive Skin.

Published in:

SOFW Journal (English version), 2025, v. 151, n. 5, p. 20

By:

Bize, C.;
Souyris, M.;
Pasquier, M.

Publication type:

Article

Research Progress on the Therapeutic Mechanisms of Stigmasterol for Multiple Diseases.

Published in:

Molecules, 2025, v. 30, n. 9, p. 1874, doi. 10.3390/molecules30091874

By:

Li, Juan;
Zheng, Xinhua;
Qi, Jinxu

Publication type:

Article

In Vivo Studies of Anticancer Peptides for Breast Cancer Therapy.

Published in:

Jundishapur Journal of Natural Pharmaceutical Products, 2025, v. 20, n. 2, p. 1, doi. 10.5812/jjnpp-160754

By:

Golestannejad, Parsa;
Monkaresi, Mohamad-Parsa;
Alizadeh-Khabaz, Farzaneh;
Mehrabi, Mohammad Reza;
Bagheri, Kamran Pooshang

Publication type:

Article

The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1534, doi. 10.3390/cancers17091534

By:

Zhao, Zuoyi;
Cutmore, Lauren C.;
Baleeiro, Renato B.;
Hartlebury, Joseph J.;
Brown, Nicholas;
Chard-Dunmall, Louisa;
Lemoine, Nicholas;
Wang, Yaohe;
Marshall, John F.

Publication type:

Article

Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1453, doi. 10.3390/cancers17091453

By:

Aniogo, Eric;
Williams, Lindsay;
Hong, Teresa;
Wong, Patty;
Hui, Susanta K.;
Ghimire, Hemendra;
Poku, Erasmus K.;
Colcher, David M.;
Yazaki, Paul J.;
Shively, John E.;
Kujawski, Maciej

Publication type:

Article

Anti-Hyperuricemic and Nephroprotective Effects of Hydrolysate Derived from Silkworm Pupae (Bombyx mori): In Vitro and In Vivo Study.

Published in:

Nutrients, 2025, v. 17, n. 9, p. 1596, doi. 10.3390/nu17091596

By:

Fan, Yuting;
Yang, Zhencong;
Lin, Xiao;
Xu, Zhoujin;
Mu, Lixia;
Li, Qingrong;
Wu, Xuli

Publication type:

Article

Neuroprotective Effects of a Combination of Dietary Trans-Resveratrol and Hesperidin Against Methylglyoxal-Induced Neurotoxicity in a Depressive Amnesia Mouse Model.

Published in:

Nutrients, 2025, v. 17, n. 9, p. 1548, doi. 10.3390/nu17091548

By:

Kim, Seon-Hyeok;
Hong, Seong-Min;
Ko, Eun-Ji;
Park, Min-Jeong;
Kim, Ji-Youn;
Kim, Sun-Yeou

Publication type:

Article

Luminal Sweet Sensing and Enteric Nervous System Participate in Regulation of Intestinal Glucose Transporter, GLUT2.

Published in:

Nutrients, 2025, v. 17, n. 9, p. 1547, doi. 10.3390/nu17091547

By:

Moran, Andrew W.;
Alrammahi, Miran;
Daly, Kristian;
Weatherburn, Darren;
Ionescu, Catherine;
Blanchard, Alexandra;
Shirazi-Beechey, Soraya P.

Publication type:

Article

Effects of Time-Restricted Fasting–Nicotinamide Mononucleotide Combination on Exercise Capacity via Mitochondrial Activation and Gut Microbiota Modulation.

Published in:

Nutrients, 2025, v. 17, n. 9, p. 1467, doi. 10.3390/nu17091467

By:

Shi, Jian;
Zhuang, Tingting;
Li, Weiye;
Wu, Xueping;
Wang, Junming;
Lyu, Ruiying;
Chen, Jingxin;
Liu, Chunhong

Publication type:

Article

(−)-Oleuropein as a Novel Metastatic Castration-Resistant Prostate Cancer Progression and Recurrence Suppressor via Targeting PCSK9-LDLR Axis.

Published in:

Nutrients, 2025, v. 17, n. 9, p. 1445, doi. 10.3390/nu17091445

By:

Ahmed, Nehal A.;
Mohyeldin, Mohamed M.;
Ebrahim, Hassan Y.;
McGehee, Oliver C.;
Tarun, Md Towhidul Islam;
El Sayed, Khalid A.

Publication type:

Article

In-depth Occlusion of Dentinal Tubules Induced by Polyaspartic Acid–Calcium and Magnesium Complexes.

Published in:

Journal of Dental Research, 2025, v. 104, n. 6, p. 637, doi. 10.1177/00220345241309340

By:

Shen, D.;
Zhu, H.;
Xu, Y.;
Zhou, Z.;
Wu, Z.;
Fu, B.

Publication type:

Article

Silencing of lncRNA PRR34‐AS1 Alleviates Alzheimer's Disease by Targeting miR‐29c‐3p to Regulate Microglia Inflammation.

Published in:

Psychogeriatrics, 2025, v. 25, n. 3, p. 1, doi. 10.1111/psyg.70043

By:

Cheng, Xing;
Chen, Hong‐Fang;
Wang, Jian‐Wei;
Pan, Xin‐Ran

Publication type:

Article

Baicalin mitigates alcoholic-associated liver disease via SOCS1-driven reprogramming of macrophages.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01110-4

By:

Huang, Sha;
Wang, Yuhua;
Wen, Jinjie;
Ji, Wenjuan;
Zeng, Qiuxiang;
Deng, Kaili;
Li, Min;
Kuang, Shanshan;
Zhang, Wen;
Chan, Mo;
Zhou, Chuying;
Lv, Zhiping;
Huang, Shaohui

Publication type:

Article

Have the Power-Rate Capabilities of Skeletal Muscles Received the Attention They Deserve? A Historical Perspective.

Published in:

International Journal of Sports Physical Therapy, 2025, v. 20, n. 5, p. 749, doi. 10.26603/001c.136971

By:

Perrine, James J.

Publication type:

Article

Author Correction: Establishing a universal IVRP method for quadrivalent HPV vaccines to replace in vivo potency tests.

Published in:

2025

By:

Hu, Jinpan;
Jia, Zijing;
Wang, Meng;
Nie, Lingling;
Fu, Wangjun;
Zhang, Qingfeng;
Qin, Haiyang;
Nie, Jianhui;
Xu, Xiaoyu;
Xu, Lingjie;
Wang, Fengze;
Chen, Yingping;
Xing, Bo;
Li, Tao;
Li, Danfeng;
Li, Shaowei;
Xia, Ningshao;
Wang, Xiangxi;
Huang, Weijin

Publication type:

Correction Notice

Deuterated water (<sup>2</sup>H<sub>2</sub>O, heavy water) labelling to investigate human cell dynamics in vivo - lessons in protocol design and toxicity from the current literature.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1544193

By:

Song, Ami;
Zhang, Yan;
Busch, Robert;
Asquith, Becca;
Macallan, Derek

Publication type:

Article

Discovery of Potential Anthelmintic Agents Against Gyrodactylus kobayashii Through Computer‐Aided Drug Design and In Vivo Evaluation.

Published in:

Journal of Fish Diseases, 2025, v. 48, n. 6, p. 1, doi. 10.1111/jfd.14102

By:

Dong, Jing;
Xia, Liwei;
Liu, Yongtao;
Yang, Qiuhong;
Xu, Ning;
Ai, Xiaohui;
Zhou, Shun

Publication type:

Article

Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01111-3

By:

Huang, Zhiqi;
Zhao, Ziyang;
Shi, Haonan;
He, Runcheng;
Feng, Qianqian;
Geng, Yang;
Zhang, Lei;
Zhang, Ti;
Yan, Zhenteng;
Jia, Zhanhong;
Jiang, Yanyan;
Sun, Jianning;
Cai, Ang;
Dong, Shifen;
Yang, Lin

Publication type:

Article

Preparation and evaluation of mesoporous Celecoxib for improved antiarthritic activity in rodents.

Published in:

Thai Journal of Pharmaceutical Sciences, 2025, v. 49, n. 1, p. 1

By:

Fernandes, Reena Inas;
Bhattacharyya, Sayani

Publication type:

Article

Activation of GLP-1R modulates the spontaneous discharge of nigral dopaminergic neurons and motor behavior in mice with chronic MPTP Parkinson's disease.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1529919

By:

Liu, Wen-Hong;
Liu, Cui;
Xue, Yan;
Sun, Xiang-Rong;
Chen, Xin-Yi;
Chen, Lei

Publication type:

Article

Validation of the Chick Chorioallantoic Membrane (CAM) Model for Biocompatibility Analysis of Biomaterials in the Context of the 3R-cascade: A Pilot Study.

Published in:

In Vivo, 2025, v. 39, n. 3, p. 1740, doi. 10.21873/invivo.13977

By:

BARBECK, MIKE;
HUEBNER, KERSTIN;
BURKHARDT, KIM;
ANDREEVA, TONYA;
KRASTEV, RUMEN;
SCHNETTLER, REINER;
STOJANOVIC, SANJA;
NAJMAN, STEVO;
JUNG, OLE;
SCHNEIDER‐STOCK, REGINE

Publication type:

Article

Preface.

Published in:

In Vivo, 2025, v. 39, n. 3, p. 1739, doi. 10.21873/invivo.13976

By:

Barbeck, Mike

Publication type:

Article

In Vivo Antitumor Activity of Allicin in a Pediatric Neuroblastoma Patient-;derived Xenograft (PDX) Mouse Model.

Published in:

In Vivo, 2025, v. 39, n. 3, p. 1283, doi. 10.21873/invivo.13932

By:

SCHULTZ, CHAD R.;
GRUHLKE, MARTIN C. H.;
SLUSARENKO, ALAN J.;
BACHMANN, ANDRÉ S.

Publication type:

Article

Quantifying Leg Muscle Disuse Atrophy During Bed Rest Using DXA, CT, and MRI.

Published in:

European Journal of Sport Science, 2025, v. 25, n. 5, p. 1, doi. 10.1002/ejsc.12299

By:

Fuchs, Cas J.;
Hermans, Wesley J. H.;
van den Hurk, Job;
Wiggins, Christopher J.;
Widholm, Per;
Dahlqvist Leinhard, Olof;
Veeraiah, Pandichelvam;
Wildberger, Joachim E.;
Prompers, Jeanine J.;
van Loon, Luc J. C.

Publication type:

Article

Preliminary study on the use of perfluoropropane contrast agent in monitoring drug diffusion during fascial plane blocks.

Published in:

BMC Anesthesiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12871-025-03028-8

By:

Zhang, Zhicheng;
Zhang, Yue;
Ni, Yong;
Wang, Lina;
Nie, Lixiang;
Zhao, Xianda

Publication type:

Article

FORMULATION AND EVALUATION OF SAXAGLIPTIN-LOADED ALGINATE MICROPARTICLES FOR SUSTAINED DRUG RELEASE.

Published in:

Biochemical & Cellular Archives, 2025, v. 25, n. 1, p. 319, doi. 10.51470/bca.2025.25.1.319

By:

Singh, Gyan;
Sharma, Satish Kumar;
Chanchal, Dilip Kumar

Publication type:

Article

Characterization of metabolic profile of Dazhu Hongjingtian and evaluation of its anti-hypoxic constituents.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 5, p. 690, doi. 10.1080/10286020.2024.2434550

By:

Ou, Chun-Yan;
Gao, Xia;
Wang, Jia-Jia;
Chen, Xia-Lin;
Cao, Liang;
Wang, Zhen-Zhong;
Zhang, Chen-Feng;
Xiao, Wei

Publication type:

Article

Progress in the study of curcumin metabolism in vivo.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 5, p. 639, doi. 10.1080/10286020.2024.2420619

By:

Zhong, Shi-Jie;
Xing, Ya-Dong;
Dong, Lu-Yao;
Chen, Yi;
Liu, Nan;
Wang, Zeng-Ming;
Zhang, Hui;
Zheng, Ai-Ping

Publication type:

Article

Rosmarinic acid suppresses the progression of COPD via Syk by modulating airway inflammation and epithelial apoptosis in vivo and in vitro.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 5, p. 732, doi. 10.1080/10286020.2024.2403617

By:

Yuan, Ji-Qiao;
Li, Xu-Yu;
Fan, Yan-Nan;
Fang, Nan;
Li, Ping;
Wen, Xin-Zhu;
Hou, Qi;
Zhang, Zi-Qian;
Lin, Ming-Bao

Publication type:

Article

Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas.

Published in:

British Journal of Dermatology, 2025, v. 192, n. 5, p. 883, doi. 10.1093/bjd/ljaf001

By:

Costanza, Mariantonia;
Giordano, Catello;
Brünneck, Ann-Christin von;
Zhao, Jing;
Makky, Ahmad;
Vinh, Katharina;
Montes-Mojarro, Ivonne Aidee;
Reisinger, Florian;
Forchhammer, Stephan;
Witalisz-Siepracka, Agnieszka;
Edtmayer, Sophie;
Stoiber, Dagmar;
Yin, Gang;
Horst, David;
Fischer, Anja;
Siebert, Reiner;
Nicolay, Jan P;
Yin, Menghong;
Janz, Martin;
Fend, Falko

Publication type:

Article

A study to assess the methodological quality of in vivo animal experiments published in Indian journal of pharmacology: A retrospective, cross-sectional, observational study.

Published in:

Indian Journal of Pharmacology, 2019, v. 51, n. 1, p. 11, doi. 10.4103/ijp.IJP_536_18

By:

Gupta, Sandeep

Publication type:

Article

Novel Human Full-Thickness Three-Dimensional Nonkeratinized Mucous Membrane Model for Pharmacological Studies in Wound Healing.

Published in:

Skin Pharmacology & Physiology, 2019, v. 32, n. 5, p. 265, doi. 10.1159/000501733

By:

Schmitt, Laurenz;
Marquardt, Yvonne;
Heise, Ruth;
von Felbert, Verena;
Amann, Philipp M.;
Huth, Laura;
Steiner, Timm;
Hölzle, Frank;
Huth, Sebastian;
Baron, Jens Malte

Publication type:

Article

In vivo Raman Microspectroscopy: Intra- and Intersubject Variability of Stratum Corneum Spectral Markers.

Published in:

Skin Pharmacology & Physiology, 2016, v. 29, n. 2, p. 102, doi. 10.1159/000445079

By:

Quatela, Alessia;
Miloudi, Lynda;
Tfayli, Ali;
Baillet-Guffroy, Arlette

Publication type:

Article