Works about IMMUNOTECHNOLOGY

Results: 287

Accelerating antibody discovery and optimization with high-throughput experimentation and machine learning.

Published in:

Journal of Biomedical Science, 2025, v. 32, n. 1, p. 1, doi. 10.1186/s12929-025-01141-x

By:

Matsunaga, Ryo;
Tsumoto, Kouhei

Publication type:

Article

A gram-scale synthesis of β-L-carbafucose for engineering antibody glycans.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01523-0

By:

Thota, V. Narasimharao;
Fers-Lidou, Anthony;
Nodwell, Matthew;
McDonagh, Anthony W.;
Gilormini, Pierre-André;
Wang, Yang;
Leung, Carolyn;
Vocadlo, David J.;
Britton, Robert

Publication type:

Article

Leveraging neonatal Fc receptor (FcRn) to enhance antibody transport across the blood brain barrier.

Published in:

Nature Communications, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41467-025-59447-1

By:

Lafrance-Vanasse, Julien;
Sadekar, Shraddha S.;
Yang, Yanli;
Yadav, Daniela Bumbaca;
Meilandt, William J.;
Wetzel-Smith, Monica K.;
Cai, Hao;
Crowell, Susan R.;
Nguyen, Van;
Lee, Vivian;
Chih, Ben;
Kwong, Mandy;
Chan, Pamela;
Santagostino, Sara;
Lee, Donna;
Chung, Shan;
Lazar, Greg A.;
Ernst, James A.;
Atwal, Jasvinder K.

Publication type:

Article

Expression of Chimeric Antibody in Mammalian Cells using Dicistronic Expression Vector.

Published in:

Biotechnology Letters, 2005, v. 27, n. 21, p. 1713, doi. 10.1007/s10529-005-2736-3

By:

Kang-Hui Xiong;
Qin-Chuan Liang;
Hua Xiong;
Chang-Xu Zou;
Guo-Dong Gao;
Zhen-Wei Zhao;
Hua Zhang

Publication type:

Article

Aglycosylated extracellular loop of inwardly rectifying potassium channel 4.1 (KCNJ10) provides a target for autoimmune neuroinflammation.

Published in:

Brain Communications, 2023, v. 5, n. 2, p. 1, doi. 10.1093/braincomms/fcad044

By:

Nicot, Arnaud B.;
Harb, Jean;
Garcia, Alexandra;
Guillot, Flora;
Hoa-Le Mai;
Mathé, Camille V.;
Morille, Jérémy;
Vallino, Amélie;
Dugast, Emilie;
Shah, Sita P.;
Lefrère, Fabienne;
Moyon, Mélinda;
Wiertlewski, Sandrine;
Le Berre, Ludmilla;
Renaudin, Karine;
Soulillou, Jean-Paul;
van Pesch, Vincent;
Brouard, Sophie;
Berthelot, Laureline;
Laplaud, David-Axel

Publication type:

Article

Antibody-based immunosuppressive agents for corneal transplantation.

Published in:

Eye (0950-222X), 2009, v. 23, n. 10, p. 1962, doi. 10.1038/eye.2008.384

By:

Thiel, M. A.;
Kaufmann, C.;
Coster, D. J.;
Williams, K. A.

Publication type:

Article

Monoclonal Antibodies: A Brief Review on Delivery Trends.

Published in:

Journal of Drug Delivery & Therapeutics, 2025, v. 15, n. 2, p. 79, doi. 10.22270/jddt.v15i2.6992

By:

Adhikari, Diwas;
Pokhrel, Sharada

Publication type:

Article

Localized fluorescent imaging of multiple proteins on individual extracellular vesicles using rolling circle amplification for cancer diagnosis.

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, p. 1, doi. 10.1002/jev2.12025

By:

Zhang, Junli;
Shi, Jinjin;
Zhang, Hongling;
Zhu, Yifan;
Liu, Wei;
Zhang, Kaixiang;
Zhang, Zhenzhong

Publication type:

Article

Localized fluorescent imaging of multiple proteins on individual extracellular vesicles using rolling circle amplification for cancer diagnosis.

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, n. 1, p. 1, doi. 10.1002/jev2.12025

By:

Zhang, Junli;
Shi, Jinjin;
Zhang, Hongling;
Zhu, Yifan;
Liu, Wei;
Zhang, Kaixiang;
Zhang, Zhenzhong

Publication type:

Article

Bispecific antibodies targeting immunomodulatory checkpoints for cancer therapy.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 3, p. 181, doi. 10.20892/j.issn.2095-3941.2023.0002

By:

Tiancheng Zhang;
Youpei Lin;
Qiang Gao

Publication type:

Article

i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44985-x

By:

Romei, Matthew G.;
Leonard, Brandon;
Katz, Zachary B.;
Le, Daniel;
Yang, Yanli;
Day, Eric S.;
Koo, Christopher W.;
Sharma, Preeti;
Bevers III, Jack;
Kim, Ingrid;
Dai, Huiguang;
Farahi, Farzam;
Lin, May;
Shaw, Andrey S.;
Nakamura, Gerald;
Sockolosky, Jonathan T.;
Lazar, Greg A.

Publication type:

Article

Computer-guided library generation applied to the optimization of single-domain antibodies.

Published in:

PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 9, p. 423, doi. 10.1093/protein/gzaa006

By:

Akiba, Hiroki;
Tamura, Hiroko;
Caaveiro, Jose M M;
Tsumoto, Kouhei

Publication type:

Article

Antibody humanization—the Influence of the antibody framework on the CDR-H3 loop ensemble in solution.

Published in:

PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 9, p. 411, doi. 10.1093/protein/gzaa004

By:

Fernández-Quintero, Monica L;
Heiss, Martin C;
Liedl, Klaus R

Publication type:

Article

Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 233, doi. 10.1093/protein/gzy002

By:

Yang, Zhuo;
Du, Mingjuan;
Wang, Wei;
Xin, Xiu;
Ma, Peixiang;
Zhang, Hongkai;
Lerner, Richard A

Publication type:

Article

Engineering of the upper hinge region of human IgG1 Fc enhances the binding affinity to FcγIIIa (CD16a) receptor isoform.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 6, p. 205, doi. 10.1093/protein/gzy019

By:

Ashoor, Dana N;
Khalaf, Noureddine Ben;
Bourguiba-Hachemi, Sonia;
Marzouq, Maryam H;
Fathallah, M Dahmani

Publication type:

Article

Engineering a high-affinity peptide binding site into the anti-CEA mAb M5A.

Published in:

PEDS: Protein Engineering, Design & Selection, 2017, v. 30, n. 6, p. 409, doi. 10.1093/protein/gzx016

By:

Zer, Cindy;
Avery, Kendra N.;
Meyer, Kassondra;
Goodstein, Leah;
Bzymek, Krzysztof P.;
Singh, Gagandeep;
Williams, John C.

Publication type:

Article

Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 10, p. 457, doi. 10.1093/protein/gzw040

By:

Schlothauer, Tilman;
Herter, Sylvia;
Koller, Claudia Ferrara;
Grau-Richards, Sandra;
Steinhart, Virginie;
Spick, Christian;
Kubbies, Manfred;
Klein, Christian;
Umaña, Pablo;
Mössner, Ekkehard

Publication type:

Article

Generation and analyses of human synthetic antibody libraries and their application for protein microarrays.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 10, p. 427, doi. 10.1093/protein/gzw042

By:

Säll, Anna;
Walle, Maria;
Wingren, Christer;
Müller, Susanne;
Nyman, Tomas;
Vala, Andrea;
Ohlin, Mats;
Borrebaeck, Carl A. K.;
Persson, Helena

Publication type:

Article

The burgeoning antibody landscape.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 10, p. 399, doi. 10.1093/protein/gzw044

By:

Huston, James S.

Publication type:

Article

Computationally driven antibody engineering enables simultaneous humanization and thermostabilization.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 10, p. 419, doi. 10.1093/protein/gzw024

By:

Yoonjoo Choi;
Christian Ndong;
Griswold, Karl E.;
Bailey-Kellogg, Chris

Publication type:

Article

TetraMabs: simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 10, p. 467, doi. 10.1093/protein/gzw037

By:

Castoldi, Raffaella;
Schanzer, Jürgen;
Panke, Christian;
Jucknischke, Ute;
Neubert, Natalie J.;
Croasdale, Rebecca;
Scheuer, Werner;
Auer, Johannes;
Klein, Christian;
Niederfellner, Gerhard;
Kobold, Sebastian;
Sustmann, Claudio

Publication type:

Article

ANTICALIgN: visualizing, editing and analyzing combined nucleotide and amino acid sequence alignments for combinatorial protein engineering.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 7, p. 263, doi. 10.1093/protein/gzw016

By:

Jarasch, Alexander;
Kopp, Melanie;
Eggenstein, Evelyn;
Richter, Antonia;
Gebauer, Michaela;
Skerra, Arne

Publication type:

Article

Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIaR131 and FcγRIIaH131.

Published in:

PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 10, p. 589, doi. 10.1093/protein/gzt022

By:

Mimoto, F.;
Katada, H.;
Kadono, S.;
Igawa, T.;
Kuramochi, T.;
Muraoka, M.;
Wada, Y.;
Haraya, K.;
Miyazaki, T.;
Hattori, K.

Publication type:

Article

Engineering at the Limits of Antibody Space.

Published in:

PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 10, p. 559, doi. 10.1093/protein/gzt051

By:

Huston, James S.

Publication type:

Article

ABangle: characterising the VH–VL orientation in antibodies.

Published in:

PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 10, p. 611, doi. 10.1093/protein/gzt020

By:

Dunbar, J.;
Fuchs, A.;
Shi, J.;
Deane, C.M.

Publication type:

Article

Antibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sources.

Published in:

PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 2, p. 101, doi. 10.1093/protein/gzs077

By:

Tillotson, Benjamin J.;
de Larrinoa, Iñigo F.;
Skinner, Colin A.;
Klavas, Derek M.;
Shusta, Eric V.

Publication type:

Article

Aggregation-resistant domain antibodies engineered with charged mutations near the edges of the complementarity-determining regions.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 591, doi. 10.1093/protein/gzs042

By:

Perchiacca, Joseph M.;
Ladiwala, Ali Reza A.;
Bhattacharya, Moumita;
Tessier, Peter M.

Publication type:

Article

Engineering antibodies for the 21st century.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 483, doi. 10.1093/protein/gzs069

By:

Huston, James S.

Publication type:

Article

Bispecific antibody derivatives with restricted binding functionalities that are activated by proteolytic processing.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 571, doi. 10.1093/protein/gzs064

By:

Metz, Silke;
Panke, Christian;
Haas, Alexander K.;
Schanzer, Jürgen;
Lau, Wilma;
Croasdale, Rebecca;
Hoffmann, Eike;
Schneider, Britta;
Auer, Johannes;
Gassner, Christian;
Bossenmaier, Birgit;
Umana, Pablo;
Sustmann, Claudio;
Brinkmann, Ulrich

Publication type:

Article

Disulfide linkage engineering for improving biophysical properties of human VH domains 6.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 581, doi. 10.1093/protein/gzs055

By:

Kim, Dae Young;
Kandalaft, Hiba;
Ding, Wen;
Ryan, Shannon;
van Faassen, Henk;
Hirama, Tomoko;
Foote, Simon J.;
MacKenzie, Roger;
Tanha, Jamshid

Publication type:

Article

Engineering a CD123xCD3 bispecific scFv immunofusion for the treatment of leukemia and elimination of leukemia stem cells.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 561, doi. 10.1093/protein/gzs040

By:

Kuo, Shu-Ru;
Wong, Lucas;
Liu, Jen-Sing

Publication type:

Article

Germline VH/VL pairing in antibodies.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 523, doi. 10.1093/protein/gzs043

By:

Jayaram, Narayan;
Bhowmick, Pallab;
Martin, Andrew C.R.

Publication type:

Article

Computer-aided antibody design.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 507, doi. 10.1093/protein/gzs024

By:

Kuroda, Daisuke;
Shirai, Hiroki;
Jacobson, Matthew P.;
Nakamura, Haruki

Publication type:

Article

Transfer of engineered biophysical properties between different antibody formats and expression systems.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 485, doi. 10.1093/protein/gzs039

By:

Schaefer, Jonas V.;
Plückthun, Andreas

Publication type:

Article

Antibody engineering reveals the important role of J segments in the production efficiency of llama single-domain antibodies in Saccharomyces cerevisiae.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 1, p. 39, doi. 10.1093/protein/gzr057

By:

Gorlani, A.;
Lutje Hulsik, D.;
Adams, H.;
Vriend, G.;
Hermans, P.;
Verrips, T.

Publication type:

Article

Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 10, p. 791, doi. 10.1093/protein/gzr038

By:

Pruzina, Sara;
Williams, Gareth T.;
Kaneva, Galina;
Davies, Sarah L.;
Martín-López, Alicia;
Brüggemann, Marianne;
Vieira, Sueli M.;
Jeffs, Simon A.;
Sattentau, Quentin J.;
Neuberger, Michael S.

Publication type:

Article

Parallel selection of antibody libraries on phage and yeast surfaces via a cross-species display.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 9, p. 711, doi. 10.1093/protein/gzr034

By:

Patel, Chirag A.;
Wang, Jinqing;
Wang, Xinwei;
Dong, Feng;
Zhong, Pingyu;
Luo, Peter P.;
Wang, Kevin C.

Publication type:

Article

Probing the stability-limiting regions of an antibody single-chain variable fragment: a molecular dynamics simulation study.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 9, p. 649, doi. 10.1093/protein/gzr029

By:

Wang, Ting;
Duan, Yong

Publication type:

Article

Broadening horizons of antibody engineering.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 9, p. 631, doi. 10.1093/protein/gzr040

By:

Huston, James S.

Publication type:

Article

Therapeutic assessment of SEED: a new engineered antibody platform designed to generate mono- and bispecific antibodies.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 5, p. 447, doi. 10.1093/protein/gzq123

By:

Muda, Marco;
Gross, Alec W.;
Dawson, Jessica P.;
He, Chaomei;
Kurosawa, Emmi;
Schweickhardt, Rene;
Dugas, Melanie;
Soloviev, Maria;
Bernhardt, Anna;
Fischer, David;
Wesolowski, John S.;
Kelton, Christie;
Neuteboom, Berend;
Hock, Bjoern

Publication type:

Article

Predicting B cell receptor substitution profiles using public repertoire data.

Published in:

PLoS Computational Biology, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.pcbi.1006388

By:

Dhar, Amrit;
Davidsen, Kristian;
IVMatsen, Frederick A.;
Minin, Vladimir N.

Publication type:

Article

A novel multi-walled carbon nanotube-based antibody conjugate for quantitative and semi-quantitative lateral flow assays.

Published in:

Bioscience, Biotechnology & Biochemistry, 2017, v. 81, n. 10, p. 1874, doi. 10.1080/09168451.2017.1365590

By:

Sun, Wenjuan;
Hu, Xiaolong;
Liu, Jia;
Zhang, Yurong;
Lu, Jianzhong;
Zeng, Libo

Publication type:

Article

Advances in Antibody Preparation Techniques for Immunoassays of Total Aflatoxin in Food.

Published in:

Molecules, 2020, v. 25, n. 18, p. 4113, doi. 10.3390/molecules25184113

By:

Wang, Yanan;
Jiang, Jinqing;
Fotina, Hanna;
Zhang, Haitang;
Chen, Junjie

Publication type:

Article

Histamine H<sub>3</sub> and H<sub>4</sub> receptors are expressed on distinct endocrine cell types in the rat fundic mucosa.

Published in:

Inflammation Research, 2008, v. 57, n. 0, p. 57, doi. 10.1007/s00011-007-0628-9

By:

Morini, G.;
Becchi, G.;
Shenton, F. C.;
Chazot, P. L.;
Grandi, D.

Publication type:

Article

Lead and Cadmium Content in Human Milk from the Northern Adriatic Area of Croatia.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1997, v. 58, n. 1, p. 16

By:

Frković, A.;
Kraš, M.;
Alebić-Juretić, A.

Publication type:

Article

Anti-Drug Antibody Response to Therapeutic Antibodies and Potential Mitigation Strategies.

Published in:

Biomedicines, 2025, v. 13, n. 2, p. 299, doi. 10.3390/biomedicines13020299

By:

Howard, Erin L.;
Goens, Melanie M.;
Susta, Leonardo;
Patel, Ami;
Wootton, Sarah K.

Publication type:

Article

Monoclonal Antibodies for Bacterial Pathogens: Mechanisms of Action and Engineering Approaches for Enhanced Effector Functions.

Published in:

Biomedicines, 2022, v. 10, n. 9, p. 2126, doi. 10.3390/biomedicines10092126

By:

Vacca, Fabiola;
Sala, Claudia;
Rappuoli, Rino

Publication type:

Article

Immunoglobulins or Antibodies: IMGT® Bridging Genes, Structures and Functions.

Published in:

Biomedicines, 2020, v. 8, n. 9, p. 319, doi. 10.3390/biomedicines8090319

By:

Lefranc, Marie-Paule;
Lefranc, Gérard

Publication type:

Article

Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor Therapy.

Published in:

2019

By:

Chen, Shixue;
Li, Lingling;
Zhang, Fan;
Wang, Yu;
Hu, Yi;
Zhao, Lei

Publication type:

journal article

Revolutionizing oncology: the role of Artificial Intelligence (AI) as an antibody design, and optimization tools.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00764-4

By:

Dewaker, Varun;
Morya, Vivek Kumar;
Kim, Yoo Hee;
Park, Sung Taek;
Kim, Hyeong Su;
Koh, Young Ho

Publication type:

Article