Works matching DE "IMMUNOTECHNOLOGY"

Results: 295

Modulating ion channels with nanobodies.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 593, doi. 10.1016/j.synbio.2025.02.005

By:

Ali, Sher;
Suris, Ashley;
Yun Huang;
Yubin Zhou

Publication type:

Article

Discovery of Synergistic Broadly Neutralizing Antibodies Targeting Non-Dominant Epitopes on SARS-CoV-2 RBD and NTD.

Published in:

Vaccines, 2025, v. 13, n. 6, p. 592, doi. 10.3390/vaccines13060592

By:

Feng, Hualong;
Wang, Zuowei;
Li, Ling;
Li, Yunjian;
Lu, Maosheng;
Chen, Xixian;
Hu, Lin;
Sun, Yi;
Du, Ruiping;
Qin, Rongrong;
Chen, Xuanyi;
Jiang, Liwei;
Zuo, Teng

Publication type:

Article

Can serum mast cell tryptase help diagnose anaphylaxis?

Published in:

Emergency Medicine Australasia, 2004, v. 16, n. 2, p. 120, doi. 10.1111/j.1742-6723.2004.00562.x

By:

Brown, Simon GA;
Blackman, Konrad E;
Heddle, Robert J

Publication type:

Article

Carbon nanotube enhanced label-free immunosensor for amperometric determination of oocyte maturation-inducing hormone in fish.

Published in:

Fish Physiology & Biochemistry, 2013, v. 39, n. 2, p. 299, doi. 10.1007/s10695-012-9700-7

By:

Hirai, Mutsuko;
Muramatsu, Tadayoshi;
Ohnuki, Hitoshi;
Hibi, Kyoko;
Ren, Huifeng;
Endo, Hideaki

Publication type:

Article

Advances in recombinant antibody manufacturing.

Published in:

Applied Microbiology & Biotechnology, 2016, v. 100, n. 8, p. 3451, doi. 10.1007/s00253-016-7388-9

By:

Kunert, Renate;
Reinhart, David

Publication type:

Article

Construction and development of a mammalian cell-based full-length antibody display library for targeting hepatocellular carcinoma.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 96, n. 5, p. 1233, doi. 10.1007/s00253-012-4243-5

By:

Li, Feng;
Liu, Yan-Hong;
Li, Yan-Wen;
Li, Yue-Hui;
Xie, Ping-Li;
Ju, Qiang;
Chen, Lin;
Li, Guan-Cheng

Publication type:

Article

Structural insights into the mechanisms and specificities of IgG-active endoglycosidases.

Published in:

Glycobiology, 2020, v. 30, n. 4, p. 268, doi. 10.1093/glycob/cwz042

By:

Du, Jonathan J;
Klontz, Erik H;
Guerin, Marcelo E;
Trastoy, Beatriz;
Sundberg, Eric J

Publication type:

Article

Unveiling inverted D genes and D-D fusions in human antibody repertoires unlocks novel antibody diversity.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-024-07441-6

By:

Prabakaran, Ponraj;
Gupta, Abhinav;
Rao, Sambasiva P.;
Rajpal, Deepak;
Wendt, Maria;
Qiu, Yu;
Chowdhury, Partha S.

Publication type:

Article

Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-021-00048-9

By:

Stüber, Jakob C.;
Rechberger, Karin F.;
Miladinović, Saša M.;
Pöschinger, Thomas;
Zimmermann, Tamara;
Villenave, Remi;
Eigenmann, Miro J.;
Kraft, Thomas E.;
Shah, Dhaval K.;
Kettenberger, Hubert;
Richter, Wolfgang F.

Publication type:

Article

Antibody engineering and its therapeutic applications.

Published in:

International Reviews of Immunology, 2023, v. 42, n. 2, p. 156, doi. 10.1080/08830185.2021.1960986

By:

Kandari, Divya;
Bhatnagar, Rakesh

Publication type:

Article

Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03673

By:

Thakkar, Shraddha;
Nanaware-Kharade, Nisha;
Celikel, Reha;
Peterson, Eric C.;
Varughese, Kottayil I.

Publication type:

Article

Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1238313

By:

Yanakieva, Desislava;
Vollmer, Lena;
Evers, Andreas;
Siegmund, Vanessa;
Arras, Paul;
Pekar, Lukas;
Doerner, Achim;
Valldorf, Bernhard;
Kolmar, Harald;
Zielonka, Stefan;
Krah, Simon

Publication type:

Article

Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1238313

By:

Yanakieva, Desislava;
Vollmer, Lena;
Evers, Andreas;
Siegmund, Vanessa;
Arras, Paul;
Pekar, Lukas;
Doerner, Achim;
Valldorf, Bernhard;
Kolmar, Harald;
Zielonka, Stefan;
Krah, Simon

Publication type:

Article

The immunogenicity of human-origin therapeutic antibodies are associated with V gene usage.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1237754

By:

Zicheng Hu;
Cohen, Sivan;
Swanson, Steven J.

Publication type:

Article

Combining deep mutational scanning to heatmap of HLA class II binding of immunogenic sequences to preserve functionality and mitigate predicted immunogenicity.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1197919

By:

Sivelle, Coline;
Sierocki, Raphael;
Lesparre, Youen;
Lomet, Aurore;
Quintilio, Wagner;
Dubois, Steven;
Correia, Evelyne;
Maria Moro, Ana;
Maillère, Bernard;
Nozach, Hervé

Publication type:

Article

Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58773-8

By:

Elliott, Isabel G.;
Fisher, Hayden;
Chan, H. T. Claude;
Inzhelevskaya, Tatyana;
Mockridge, C. Ian;
Penfold, Christine A.;
Duriez, Patrick J.;
Orr, Christian M.;
Herniman, Julie;
Müller, Kri T. J.;
Essex, Jonathan W.;
Cragg, Mark S.;
Tews, Ivo

Publication type:

Article

Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56478-6

By:

Xie, Bin;
Xu, Shipeng;
Sivasankar, Sanjeevi

Publication type:

Article

Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants.

Published in:

Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00794-7

By:

Li, Lili;
Gao, Meiling;
Jiao, Peng;
Zu, Shulong;
Deng, Yong-qiang;
Wan, Dingyi;
Cao, Yang;
Duan, Jing;
Aliyari, Saba R;
Li, Jie;
Shi, Yueyue;
Rao, Zihe;
Qin, Cheng-feng;
Guo, Yu;
Cheng, Genhong;
Yang, Heng

Publication type:

Article

Human monoclonal anti-TLR4 antibody negatively regulates lipopolysaccharide-induced inflammatory responses in mouse macrophages.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 5, p. 4125

By:

Wang, Yiwen;
Gong, Dandan;
Yao, Chuanxia;
Zheng, Feng;
Zhou, Tingting;
Cao, Qingxin;
Zhu, Xuhui;
Wang, Maorong;
Zhu, Jin

Publication type:

Article

Optimizing Antibody Affinity and Developability Using a Framework–CDR Shuffling Approach—Application to an Anti-SARS-CoV-2 Antibody.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 12, p. 2694, doi. 10.3390/v14122694

By:

Gopal, Ranjani;
Fitzpatrick, Emmett;
Pentakota, Niharika;
Jayaraman, Akila;
Tharakaraman, Kannan;
Capila, Ishan

Publication type:

Article

Simultaneous prediction of antibody backbone and side-chain conformations with deep learning.

Published in:

PLoS ONE, 2022, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0258173

By:

Akpinaroglu, Deniz;
Ruffolo, Jeffrey A.;
Mahajan, Sai Pooja;
Gray, Jeffrey J.

Publication type:

Article

Toll-free vaccines?

Published in:

Nature Biotechnology, 2007, v. 25, n. 3, p. 303, doi. 10.1038/nbt0307-303

By:

Krieg, Arthur M

Publication type:

Article

Transgenic commensals as mucosal protectants.

Published in:

Nature Biotechnology, 2000, v. 18, n. 10, p. 1038, doi. 10.1038/80220

By:

Whaley, Kevin J.;
Zeitlin, Larry

Publication type:

Article

Antibody arrays for high-throughput screening of antibody?antigen interactions.

Published in:

Nature Biotechnology, 2000, v. 18, n. 9, p. 989, doi. 10.1038/79494

By:

de Wildt, Ruud M. T.;
Mundy, Chris R.;
Gorick, Barbara D.;
Tomlinson, Ian M.

Publication type:

Article

Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries.

Published in:

Nature Biotechnology, 2000, v. 18, n. 8, p. 852, doi. 10.1038/78458

By:

Söderlind, Eskil;
Strandberg, Leif;
Jirholt, Pernilla;
Kobayashi, Norihiro;
Alexeiva, Vessela;
Åberg, Anna-Maria;
Nilsson, Anna;
Jansson, Bo;
Ohlin, Mats;
Wingren, Christer;
Danielsson, Lena;
Carlsson, Roland;
Borrebaeck, Carl A.K.

Publication type:

Article

Exploiting recombination in single bacteria to make large phage antibody libraries.

Published in:

Nature Biotechnology, 2000, v. 18, n. 1, p. 75, doi. 10.1038/71958

By:

Sblattero, Daniele;
Bradbury, Andrew

Publication type:

Article

Therapeutic antibody fragments with prolonged in vivo half-lives.

Published in:

Nature Biotechnology, 1999, v. 17, n. 8, p. 780, doi. 10.1038/11717

By:

Chapman, Andrew P.;
Antoniw, Pari;
Spitali, Mariangela;
West, Shauna;
Stephens, Sue;
King, David J.

Publication type:

Article

First‐in‐Human Dose Selection for T‐Cell Engaging Bispecific Antibodies.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 1, p. 11, doi. 10.1002/cpt.3487

By:

van der Graaf, Piet H.

Publication type:

Article

Passive antibody therapy for infectious diseases.

Published in:

Nature Reviews Microbiology, 2004, v. 2, n. 9, p. 695, doi. 10.1038/nrmicro974

By:

Casadevall, Arturo;
Dadachova, Ekaterina;
Pirofski, Liise-anne

Publication type:

Article

Protein arrays: An apt solution?

Published in:

Nature, 2006, v. 444, n. 7121, p. 960, doi. 10.1038/444960a

By:

M. E.

Publication type:

Article

MVSF-AB: accurate antibody–antigen binding affinity prediction via multi-view sequence feature learning Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 5, p. 1, doi. 10.1093/bioinformatics/btae579

By:

Li, Minghui;
Shi, Yao;
Hu, Shengqing;
Hu, Shengshan;
Guo, Peijin;
Wan, Wei;
Zhang, Leo Yu;
Pan, Shirui;
Li, Jizhou;
Sun, Lichao;
Lan, Xiaoli

Publication type:

Article

AbDiver: a tool to explore the natural antibody landscape to aid therapeutic design.

Published in:

Bioinformatics, 2022, v. 38, n. 9, p. 2628, doi. 10.1093/bioinformatics/btac151

By:

Młokosiewicz, Jakub;
Deszyński, Piotr;
Wilman, Wiktoria;
Jaszczyszyn, Igor;
Ganesan, Rajkumar;
Kovaltsuk, Aleksandr;
Leem, Jinwoo;
Galson, Jacob D;
Krawczyk, Konrad

Publication type:

Article

Antibody-based immunosuppressive agents for corneal transplantation.

Published in:

Eye (0950-222X), 2009, v. 23, n. 10, p. 1962, doi. 10.1038/eye.2008.384

By:

Thiel, M. A.;
Kaufmann, C.;
Coster, D. J.;
Williams, K. A.

Publication type:

Article

Anti-Drug Antibody Response to Therapeutic Antibodies and Potential Mitigation Strategies.

Published in:

Biomedicines, 2025, v. 13, n. 2, p. 299, doi. 10.3390/biomedicines13020299

By:

Howard, Erin L.;
Goens, Melanie M.;
Susta, Leonardo;
Patel, Ami;
Wootton, Sarah K.

Publication type:

Article

Monoclonal Antibodies for Bacterial Pathogens: Mechanisms of Action and Engineering Approaches for Enhanced Effector Functions.

Published in:

Biomedicines, 2022, v. 10, n. 9, p. 2126, doi. 10.3390/biomedicines10092126

By:

Vacca, Fabiola;
Sala, Claudia;
Rappuoli, Rino

Publication type:

Article

Immunoglobulins or Antibodies: IMGT® Bridging Genes, Structures and Functions.

Published in:

Biomedicines, 2020, v. 8, n. 9, p. 319, doi. 10.3390/biomedicines8090319

By:

Lefranc, Marie-Paule;
Lefranc, Gérard

Publication type:

Article

Impact of the conjugation of antibodies to the surfaces of polymer nanoparticles on the immune cell targeting abilities.

Published in:

Nano Convergence, 2021, v. 8, n. 1, p. 1, doi. 10.1186/s40580-021-00274-7

By:

Lee, Na Kyeong;
Wang, Chi-Pin James;
Lim, Jaesung;
Park, Wooram;
Kwon, Ho-Keun;
Kim, Se-Na;
Kim, Tae-Hyung;
Park, Chun Gwon

Publication type:

Article

Extended Half-life Antibodies: A Narrative Review of a New Approach in the Management of Atopic Dermatitis.

Published in:

Dermatology & Therapy, 2024, v. 14, n. 9, p. 2393, doi. 10.1007/s13555-024-01253-6

By:

Yilmaz, Orhan;
Torres, Tiago

Publication type:

Article

TEMPRO: nanobody melting temperature estimation model using protein embeddings.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-70101-6

By:

Alvarez, Jerome Anthony E.;
Dean, Scott N.

Publication type:

Article

Therapeutic Opportunities with Pharmacological Inhibition of CD38 with Isatuximab.

Published in:

Cells (2073-4409), 2019, v. 8, n. 12, p. 1522, doi. 10.3390/cells8121522

By:

Martin, Thomas G.;
Corzo, Kathryn;
Chiron, Marielle;
van de Velde, Helgi;
Abbadessa, Giovanni;
Campana, Frank;
Solanki, Malini;
Meng, Robin;
Lee, Helen;
Wiederschain, Dmitri;
Zhu, Chen;
Rak, Alexey;
Anderson, Kenneth C.

Publication type:

Article

Tolerance and immunological changes of chemically modified allergen vaccine of Parietaria judaica in accelerated schedules.

Published in:

Clinical & Experimental Immunology, 2007, v. 147, n. 3, p. 491, doi. 10.1111/j.1365-2249.2006.03309.x

By:

Asturias, J. A.;
Ferrer, A.;
Arilla, M. C.;
Andreu, C.;
Madariaga, B.;
Martínez, A.

Publication type:

Article

Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27397-z

By:

Pennington, Luke F.;
Gasser, Pascal;
Kleinboelting, Silke;
Zhang, Chensong;
Skiniotis, Georgios;
Eggel, Alexander;
Jardetzky, Theodore S.

Publication type:

Article

Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26620-1

By:

Jo, Gyunghee;
Bae, Jeomil;
Hong, Ho Jeong;
Han, Ah-reum;
Kim, Do-Kyun;
Hong, Seon Pyo;
Kim, Jung A;
Lee, Sangkyu;
Koh, Gou Young;
Kim, Ho Min

Publication type:

Article

A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25777-z

By:

Chen, Xun;
Gentili, Matteo;
Hacohen, Nir;
Regev, Aviv

Publication type:

Article

Antibody Engineering to Enhancement of Ranibizumab Binding Affinity for the Prevention and Treatment of Diabetic Retinopathy.

Published in:

Iranian Journal of Diabetes & Obesity (IJDO), 2024, v. 16, n. 2, p. 112, doi. 10.18502/ijdo.v16i2.15710

By:

Sefid, Fateme;
Monshizadeh, Kimia;
Azamirad, Ghasem;
Vahidi Mehrjardi, Mohammad Yahya

Publication type:

Article

Biosimilars Targeting Pathogens: A Comprehensive Review of Their Role in Bacterial, Fungal, Parasitic, and Viral Infections.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 581, doi. 10.3390/pharmaceutics17050581

By:

Halawa, Mohamed;
ElSayed, Ramez M. Rashad;
Aderibigbe, Tope;
Newman, Precious M.;
Reid, Briana E.;
Carabetta, Valerie J.

Publication type:

Article

Approaches to Reducing Normal Tissue Radiation from Radiolabeled Antibodies.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 4, p. 508, doi. 10.3390/ph17040508

By:

Suzuki, Hiroyuki;
Kannaka, Kento;
Uehara, Tomoya

Publication type:

Article

Serologic associations of anti-cytoplasmic antibodies identified during anti-nuclear antibody testing.

Published in:

Clinical Chemistry & Laboratory Medicine, 2006, v. 44, n. 10, p. 1283, doi. 10.1515/CCLM.2006.232

By:

Craig, Wendy Y.;
Ledue, Thomas B.;
Collins, Marilyn F.;
Meggison, William E.;
Leavitt, Lynda F.;
Ritchie, Robert F.

Publication type:

Article

pH-responsive antibodies for therapeutic applications.

Published in:

Journal of Biomedical Science, 2021, v. 28, n. 1, p. 1, doi. 10.1186/s12929-021-00709-7

By:

Klaus, Tomasz;
Deshmukh, Sameer

Publication type:

Article

Development of therapeutic antibodies for the treatment of diseases.

Published in:

Journal of Biomedical Science, 2020, v. 27, n. 1, p. 1, doi. 10.1186/s12929-019-0592-z

By:

Lu, Ruei-Min;
Hwang, Yu-Chyi;
Liu, I-Ju;
Lee, Chi-Chiu;
Tsai, Han-Zen;
Li, Hsin-Jung;
Wu, Han-Chung

Publication type:

Article