Works matching DE "IMMUNE checkpoint proteins"

Results: 5000

Clinical Relevance of FOXP3 , PD-L1 , PD-1 , and miR-155 Gene Expression and Genetic Variants in HPV-Negative Oral Carcinomas.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7218, doi. 10.3390/ijms26157218

By:

Ivkovic, Nemanja;
Misic, Debora;
Kozomara, Ruzica;
Jovic, Sasa;
Sami, Ahmad;
Velikic, Gordana;
Stosic, Srboljub;
Supic, Gordana

Publication type:

Article

Sequential treatment with PARPi and WEE1i enhances antitumor immune responses in preclinical models of ovarian cancer.

Published in:

Science Translational Medicine, 2025, v. 17, n. 811, p. 1, doi. 10.1126/scitranslmed.adu6989

By:

Jiao, Xiaofei;
Liu, Jiahao;
Wu, Yijie;
Zhong, Qing;
Zhu, Li;
Wang, Linghui;
Li, Huayi;
Xiang, Minghua;
Zhao, Xuejiao;
Zhao, Guangnian;
Mills, Gordon B.;
Ma, Ding;
Gao, Qinglei;
Fang, Yong

Publication type:

Article

Immune Evasion in Head and Neck Squamous Cell Carcinoma: Roles of Cancer-Associated Fibroblasts, Immune Checkpoints, and TP53 Mutations in the Tumor Microenvironment.

Published in:

Cancers, 2025, v. 17, n. 15, p. 2590, doi. 10.3390/cancers17152590

By:

Tsai, Chung-Che;
Hsu, Yi-Chiung;
Chu, Tin-Yi;
Hsu, Po-Chih;
Kuo, Chan-Yen

Publication type:

Article

Bioinformatics Screening of Tumor-Derived Neuropeptides Mediating Neuroimmune Axis of Head and Neck Cancer.

Published in:

Cancers, 2025, v. 17, n. 15, p. 2464, doi. 10.3390/cancers17152464

By:

Kishan, Ravi;
Zhang, Gao;
Yang, Weifa;
Su, Yuxiong

Publication type:

Article

Identification of a TIGIT-expressing CD8<sup>+</sup> T cell subset as a potential prognostic biomarker in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1626367

By:

Cao, Shouli;
Wang, Meidan;
Sun, Weiqiang;
Ma, Zhibin;
Yang, Kun;
Li, Ting;
Zhu, Xuedan;
Pei, Yang;
Pan, Mingyue;
Wang, Liqun;
Ding, Honglin

Publication type:

Article

Unveiling B7/CD28 family proteins in hepatocellular carcinoma: insights into communication and prognostic significance.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1583597

By:

Cai, Yan;
Liu, Xiaodi;
He, Tao;
Xu, Yangming;
Chen, Shuxian;
Tan, Xianliang;
Wei, Shouchao;
Wu, Zimeng;
Xiao, Liying;
Luo, Baoming

Publication type:

Article

Verbascoside A as Potent Compound of Cyperus rotundus in Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4) Inhibition Based on Computational Model.

Published in:

Tropical Journal of Natural Product Research, 2025, v. 9, n. 7, p. 3291, doi. 10.26538/tjnpr/v9i7.57

By:

Setiawan, Meddy;
Agustini, Sulistyo M.;
Bahrudin, Mochamad;
Lestari, Noviana D.;
Rifa'i, Muhaimin

Publication type:

Article

GPER1 is involved in shaping tumor immune microenvironment and its expression is decreased in NSCLC tumorigenesis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-15405-x

By:

Li, Zhenhua;
Xie, Chao;
Cui, Jingjing;
Xu, Hui;
Li, Dingbiao

Publication type:

Article

Identification of a TIGIT-expressing CD8<sup>+</sup> T cell subset as a potential prognostic biomarker in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1626367

By:

Cao, Shouli;
Wang, Meidan;
Sun, Weiqiang;
Ma, Zhibin;
Yang, Kun;
Li, Ting;
Zhu, Xuedan;
Pei, Yang;
Pan, Mingyue;
Wang, Liqun;
Ding, Honglin

Publication type:

Article

Dual Targeting of Inflammatory and Immune Checkpoint Pathways to Overcome Radiotherapy Resistance in Esophageal Squamous Cell Carcinoma.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 9091, doi. 10.2147/JIR.S531145

By:

Qu, Zhifeng;
Shi, Linlin;
Wang, Pei;
Zhao, Anshun;
Zheng, Xuewei;
Yin, Qinan

Publication type:

Article

TRIP13-induced NUSAP1 upregulation promotes CcRCC progression through EMT and PI3K/AKT/mTOR pathway.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06761-3

By:

Chen, Xiaolong;
Wang, Qing;
Zhu, Zhiqiang;
Peng, Zheng;
Huang, Kunyuan;
Deng, Guanyun;
Jiang, Kehua;
Chen, Kun;
Sun, Fa

Publication type:

Article

Neurotransmitters: an emerging target for therapeutic resistance to tumor immune checkpoint inhibitors.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02413-8

By:

Yang, Jiyuan;
Wu, Yu;
Lv, Xinhui;
Liu, Sicong;
Yuan, Ziwen;
Chen, Yafang;
Ding, Xiangyu;
Li, Zhong;
Wang, Xudong

Publication type:

Article

Barking up the right tree: Immune checkpoint signatures of human and dog cancers.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 8, p. 1, doi. 10.1371/journal.pcbi.1013270

By:

Kocikowski, Mikolaj;
Yébenes Mayordomo, Marcos;
Alfaro, Javier;
Parys, Maciej

Publication type:

Article

CD24a knockout results in an enhanced macrophage- and CD8⁺ T cell-mediated anti-tumor immune responses in tumor microenvironment in a murine triple-negative breast cancer model.

Published in:

Journal of Biomedical Science, 2025, v. 32, n. 1, p. 1, doi. 10.1186/s12929-025-01165-3

By:

Chan, Shih-Hsuan;
Lin, Chin-Yu;
Tseng, Hsuan-Jung;
Wang, Lu-Hai

Publication type:

Article

Tumor-infiltrating lymphocytes in NSCLC: from immune surveillance to immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1610998

By:

Xue, Haiyi;
Fan, Yilan;
Li, Yi;
Zhao, Qian;
Zhang, Xuelu;
Zhao, Pei;
Liu, Zhenjun

Publication type:

Article

Emerging IO checkpoints in gastrointestinal oncology.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1575713

By:

Tojjari, Alireza;
Saeed, Anwaar;
Cavalcante, Ludimila

Publication type:

Article

Revolutionizing cervical cancer treatment: single-cell sequencing of TSPAN1+ tumor EPCs and immune checkpoints to assess drug sensitivity and optimize therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1574174

By:

Li, Yumeng;
Lin, Zhiheng;
Lin, Guangyao;
Zhao, Zhijie;
Xiahou, Zhikai;
Cai, Pingping

Publication type:

Article

Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61822-x

By:

Llaó-Cid, L.;
Wong, JKL;
Fernandez Botana, I.;
Paul, Y.;
Wierz, M.;
Pilger, L-M;
Floerchinger, A.;
Tan, CL;
Gonder, S.;
Pagano, G.;
Chazotte, M.;
Bestak, K.;
Schifflers, C.;
Iskar, M.;
Roider, T.;
Czernilofsky, F.;
Bruch, P-M;
Mallm, JP;
Cosma, A.;
Campton, DE

Publication type:

Article

Decoding the epigenetic-immune nexus in hepatocellular carcinoma: a Mendelian randomization study reveals BTN3A2, S100A12 and TRIM27 as white blood cell regulators.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14693-w

By:

Qiu, Yang;
Zhang, Haiyan;
Yu, Xiao;
Pan, Jielu;
Xiao, Dinghong;
Miao, Hongyu;
Wang, Ruiqing;
Shen, Nan;
Pu, Peimin;
Zhou, Yinling;
Liu, Zhidong;
He, Lin;
Xing, Lianjun

Publication type:

Article

New Immune Target Offers Hope for Treatment-Resistant Blood Cancers.

Published in:: Indian Practitioner, 2025, v. 78, n. 7, p. 10
Publication type:: Article

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease.

Published in:

Science Translational Medicine, 2025, v. 17, n. 810, p. 1, doi. 10.1126/scitranslmed.adv4071

By:

Arai, Yohei;
Chavkin, Nicholas W.;
Arai, Yuka;
Halvardson, Jonatan;
Bjurling, Josefin;
Doviak, Heather;
Cochran, Jesse D.;
Evans, Megan A.;
Horitani, Keita;
Yura, Yoshimitsu;
Miura-Yura, Emiri;
Sano, Soichi;
Forsberg, Lars A.;
Walsh, Kenneth

Publication type:

Article

Moving the needle on immune checkpoint inhibitors with novel targets: are we being TIMid or LAGging behind?

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf145

By:

Park, Changsu Lawrence;
Bedard, Philippe L

Publication type:

Article

Strategies to Overcome PD-1/PD-L1 Blockade Resistance: Focusing on Combination with Immune Checkpoint Blockades.

Published in:

Journal of Cancer, 2025, v. 16, n. 11, p. 3425, doi. 10.7150/jca.108163

By:

Dinglin Liu;
Haoyue Xiao;
Ying Xiang;
Dian Zhong;
Yuchen Liu;
Yunfei Wang;
Weijia Zhang

Publication type:

Article

Office-based flexible sigmoidoscopy allows rapid assessment and management of suspected immune checkpoint inhibitor-related colitis.

Published in:

Annals of Gastroenterology, 2025, v. 38, n. 4, p. 415, doi. 10.20524/aog.2025.0979

By:

Siev, Alana;
Livingstone, Pamela;
Tom, Erika;
Corso, Tara;
Preeshagul, Isabel;
Postow, Michael;
Shah, Neil J.;
Niec, Rachel;
Schattner, Mark;
Faleck, David M.

Publication type:

Article

Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61427-4

By:

Barisa, Marta;
Muller, Henrike P.;
Zappa, Elisa;
Shah, Rivani;
Buhl, Juliane L.;
Draper, Benjamin;
Himsworth, Courtney;
Bowers, Chantelle;
Munnings-Tomes, Sophie;
Nicolaidou, Marilena;
Morlando, Sonia;
Birley, Kathleen;
Leboreiro-Babe, Clara;
Vitali, Alice;
Privitera, Laura;
O'Sullivan, Kyle;
Greppi, Ailsa;
Buschhaus, Magdalena;
Román, Mario Barrera;
de Blank, Sam

Publication type:

Article

Promotion of the invasion and metastasis of breast cancer by B7-H3 through CCR5High tumor-associated macrophages.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03932-6

By:

Dai, Tiantian;
Xu, Zhihua;
Li, Yadi;
Wu, Mengni;
Qiu, Yue;
Chao, ZhuJun;
Jiang, Renhai;
Chen, Yan;
Lu, Linlin

Publication type:

Article

Unraveling the glyco-immunity nexus in pancreatic cancer.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02417-4

By:

Rajesh, Christabelle;
Cummings, Richard D.;
Radhakrishnan, Prakash

Publication type:

Article

A novel bispecific aptamer targeting LAG3 and HER2 enhances T cell-mediated immunotherapy against HER2-positive cancer cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1557910

By:

Guo, Rui;
Chen, Xiaoyang;
Ying, Lu;
Zhang, Wenjing;
Sabeel, Zufa;
Zhao, Lianhui;
Dong, Jian;
Dong, Yiyang;
Yang, Zhao

Publication type:

Article

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1568431

By:

Reitsema, Rosanne D.;
Kurt, Seta;
Rangel, Ignacio;
Hjelmqvist, Hans;
Dreifaldt, Mats;
Sirsjö, Allan;
Kumawat, Ashok Kumar

Publication type:

Article

TIPE2 combined with immune cell infiltration predicts prognosis in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10449-5

By:

Xia, Hengbo;
Pang, Qingqing;
Xu, Aman;
Hu, Jie

Publication type:

Article

Tumor-restricted activation of Vγ9Vδ2 T cells via bispecific Evobodies: a novel strategy for safe and potent immunotherapy in ovarian cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1628501

By:

Oberg, Hans-Heinrich;
Deseke, Malte;
Krohn, Steffen;
Winterberg, Dorothee;
Peipp, Matthias;
Bauerschlag, Dirk;
Künkele, Klaus-Peter;
Wesch, Daniela;
Baumann, Christoph

Publication type:

Article

Fluorinated small molecule derivatives in cancer immunotherapy: emerging frontiers and therapeutic potential.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1622091

By:

Leong, Ka Fai;
Chen, Zihan;
Coghi, Paolo

Publication type:

Article

Characterization of novel anoikis-related genes as prognostic biomarkers and key determinants of the immune microenvironment in esophageal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1599171

By:

Su, Yani;
Zhang, Ming;
Xu, Peng;
Wen, Pengfei;
Xu, Ke;
Xie, Jiale;
Wan, Xianjie;
Liu, Lin;
Yang, Zhi;
Yang, Mingyi

Publication type:

Article

The immune microenvironment in endometrial carcinoma: mechanisms and therapeutic targeting.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586315

By:

Wang, Yilin;
Liu, Nana;
Guo, Xiangcui;
Han, Ruobing;
Bai, Jin;
Zhong, Jiateng;
Wang, Qianqing

Publication type:

Article

FLT3-ITD promotes immune checkpoint CD80 via ROS elevation in acute myeloid leukemia.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1577313

By:

Yan, Libo;
Zhang, Weiming;
Mo, Qiyan;
Wang, Daogang;
Xu, Ning;
Yang, Mengzhe;
Ren, Tao

Publication type:

Article

Targeting the Tumor Microenvironment in Hodgkin Lymphoma: Challenges and Therapeutic Strategies.

Published in:

Biocell, 2025, v. 49, n. 7, p. 1185, doi. 10.32604/biocell.2025.063572

By:

Laddaga, Filomena Emanuela;
Pinto, Pamela;
Daraia, Bruna;
D'amato, Antonio;
D'oronzo, Stella;
Martinotti, Stefano;
Gaudio, Francesco

Publication type:

Article

Advancements in Cancer Therapy: Mycoviruses and Their Oncolytic Potential.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 1329, doi. 10.1007/s12013-024-01608-y

By:

Kamala, Kannan;
Ganapathy, Dhanraj;
Sivaperumal, Pitchiah

Publication type:

Article

Shedding Light on the Role of Exosomal PD-L1 (ExoPD-L1) in Cancer Progression: an Update.

Published in:

Cell Biochemistry & Biophysics, 2024, v. 82, n. 3, p. 1709, doi. 10.1007/s12013-024-01340-7

By:

Sun, Dongmei;
Altalbawy, Farag M. A.;
Yumashev, Alexey;
Hjazi, Ahmed;
Menon, Soumya V.;
Kaur, Mandeep;
Deorari, Mahamedha;
Abdulwahid, Alzahraa S.;
Shakir, Maha Noori;
Gabal, Baneen Chasib

Publication type:

Article

Monoclonal Antibodies in Oncology: A Decade of Novel Options.

Published in:

Cell Biochemistry & Biophysics, 2023, v. 81, n. 3, p. 395, doi. 10.1007/s12013-023-01144-1

By:

Kardile, Vaibhavi;
Kulkarni, Atharva;
Nadar, Brinda;
Saldanha, Tina

Publication type:

Article

Molecular Characterization of Cuproptosis-related lncRNAs: Defining Molecular Subtypes and a Prognostic Signature of Ovarian Cancer.

Published in:

Biological Trace Element Research, 2024, v. 202, n. 4, p. 1428, doi. 10.1007/s12011-023-03780-3

By:

Li, Nan;
Yu, Kai;
Huang, Delun;
Li, Shu;
Zeng, Dingyuan;
Li, Jingjing;
Fan, Li

Publication type:

Article

Improving IL12 immunotherapy in glioblastoma by targeting the long noncoding RNA INCR1.

Published in:

Journal of Neuro-Oncology, 2025, v. 173, n. 1, p. 205, doi. 10.1007/s11060-025-04978-2

By:

Saini, Shikha;
Gadet, Josephina A. M. A.;
Freeman, Gordon J.;
Chiocca, E. Antonio;
Mineo, Marco

Publication type:

Article

BRD4 promotes immune escape of glioma cells by upregulating PD-L1 expression.

Published in:

Journal of Neuro-Oncology, 2025, v. 171, n. 3, p. 669, doi. 10.1007/s11060-024-04889-8

By:

Liu, Yongsheng;
Cai, Lize;
Wang, Hao;
Yao, Lin;
Wu, Yue;
Zhang, Kai;
Su, Zuopeng;
Zhou, Youxin

Publication type:

Article

Tumor immune microenvironment in pituitary neuroendocrine tumors (PitNETs): increased M2 macrophage infiltration and PD-L1 expression in PIT1-lineage subset.

Published in:

Journal of Neuro-Oncology, 2023, v. 163, n. 3, p. 663, doi. 10.1007/s11060-023-04382-8

By:

Luo, Mei;
Tang, Rui;
Wang, Haijun

Publication type:

Article

Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of neuropathology in the management of progressive glioblastoma in adults.

Published in:

Journal of Neuro-Oncology, 2022, v. 158, n. 2, p. 179, doi. 10.1007/s11060-022-04005-8

By:

Goodman, Abigail L.;
Velázquez Vega, José E.;
Glenn, Chad;
Olson, Jeffrey J.

Publication type:

Article

Immune-related aseptic meningitis and strategies to manage immune checkpoint inhibitor therapy: a systematic review.

Published in:

Journal of Neuro-Oncology, 2022, v. 157, n. 3, p. 533, doi. 10.1007/s11060-022-03997-7

By:

Nannini, Simon;
Koshenkova, Larysa;
Baloglu, Seyyid;
Chaussemy, Dominique;
Noël, Georges;
Schott, Roland

Publication type:

Article

Introduction to mammalian genome special issue: the microbiome in human health and disease.

Published in:

2021

By:

Pavlovic, Guillaume;
Seong, Je Kyung;
Weinstock, George M.

Publication type:

Editorial

A review on the role of gut microbiota in immune checkpoint blockade therapy for cancer.

Published in:

Mammalian Genome, 2021, v. 32, n. 4, p. 223, doi. 10.1007/s00335-021-09867-3

By:

Kim, Esther;
Ahn, Hyeok;
Park, Hansoo

Publication type:

Article

PD-L1 expression in high-risk non-muscle invasive bladder cancer is not a biomarker of response to BCG.

Published in:

World Journal of Urology, 2025, v. 43, n. 1, p. 1, doi. 10.1007/s00345-024-05392-5

By:

de Jong, Florus C.;
Kvikstad, Vebjørn;
Hoedemaeker, Robert F.;
van der Made, Angelique C. J.;
van der Bosch, Thierry P.;
van Casteren, Niels J.;
van Kessel, Kim E. M.;
Zwarthoff, Ellen C.;
Boormans, Joost L.;
Zuiverloon, Tahlita C. M.

Publication type:

Article

PD-L1 testing in urothelial bladder cancer: essentials of clinical practice.

Published in:

World Journal of Urology, 2021, v. 39, n. 5, p. 1345, doi. 10.1007/s00345-020-03498-0

By:

Rouanne, Mathieu;
Radulescu, Camélia;
Adam, Julien;
Allory, Yves

Publication type:

Article

Immunotherapy in prostate cancer: new horizon of hurdles and hopes.

Published in:

World Journal of Urology, 2021, v. 39, n. 5, p. 1387, doi. 10.1007/s00345-020-03497-1

By:

Tsaur, Igor;
Brandt, Maximilian P.;
Juengel, Eva;
Manceau, Cécile;
Ploussard, Guillaume

Publication type:

Article