Works matching DE "IMINOSUGARS"

Results: 111

Exploring the Chemistry and Applications of Thio-, Seleno-, and Tellurosugars.

Published in:

Molecules, 2025, v. 30, n. 9, p. 2053, doi. 10.3390/molecules30092053

By:

Martínez-Pascual, Roxana;
Valera-Zaragoza, Mario;
Fernández-Bolaños, José G.;
López, Óscar

Publication type:

Article

Potent and Selective Cell‐Active Iminosugar Inhibitors of Human α‐N‐Acetylgalactosaminidase (α‐NAGAL).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 44, p. 1, doi. 10.1002/chem.202300982

By:

Ashmus, Roger A.;
Wang, Yang;
González‐Cuesta, Manuel;
King, Dustin T.;
Tiet, Ben;
Chen, Xi;
Zhu, Yanping;
Kirk, Bryce;
García Fernandez, José M.;
Ortiz Mellet, Carmen;
Britton, Robert;
Vocadlo, David J.

Publication type:

Article

Diversity-oriented synthesis of glycomimetics.

Published in:

Communications Chemistry, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42004-021-00520-3

By:

Meanwell, Michael;
Fehr, Gaelen;
Ren, Weiwu;
Adluri, Bharanishashank;
Rose, Victoria;
Lehmann, Johannes;
Silverman, Steven M.;
Rowshanpour, Rozhin;
Adamson, Christopher;
Bergeron-Brlek, Milan;
Foy, Hayden;
Challa, Venugopal Rao;
Campeau, Louis-Charles;
Dudding, Travis;
Britton, Robert

Publication type:

Article

Divergent Synthesis of Bicyclic Iminosugars: Preparation of (−)‐Swainsonine‐Based Alkaloids and Their Inhibition Study towards α‐Human Mannosidases.

Published in:

Asian Journal of Organic Chemistry, 2019, v. 8, n. 12, p. 2233, doi. 10.1002/ajoc.201900637

By:

Chen, Wei‐An;
Sayyad, Ashik;
Chen, Chiao‐Wen;
Chen, Yu‐Hsin;
Cheng, Ting‐Jen R.;
Cheng, Wei‐Chieh

Publication type:

Article

Epimerization of the α Stereocenter in d-Ribose-Derived Nitrones: Direct Access to Variant Quinolizidines with d-Ribo and d-Arabino Configurations.

Published in:

Asian Journal of Organic Chemistry, 2015, v. 4, n. 8, p. 733, doi. 10.1002/ajoc.201500118

By:

Rowicki, Tomasz;
Malinowski, Maciej;
Łapczyński, Sebastian;
Gryszel, Maciej;
Czerwińska, Karolina;
Madura, Izabela;
Sas, Wojciech

Publication type:

Article

Lucerastat, an iminosugar with potential as substrate reduction therapy for glycolipid storage disorders: safety, tolerability, and pharmacokinetics in healthy subjects.

Published in:

2017

By:

Guérard, N.;
Morand, O.;
Dingemanse, J.

Publication type:

journal article

N-2 Alkylated analogues of aza-galactofagomine as potential inhibitors of β-glucosidase.

Published in:

Journal of the Serbian Chemical Society, 2024, v. 89, n. 10, p. 1255, doi. 10.2298/JSC240315062D

By:

ĐURKOVIĆ, FILIP;
ZLATOVIĆ, MARIO;
SLADIĆ, DUŠAN;
NOVAKOVIĆ, IRENA;
BIHELOVIĆ, FILIP;
FERJANČIĆ, ZORANA

Publication type:

Article

Synthesis of N -Substituted Iminosugar C -Glycosides and Evaluation as Promising α -Glucosidase Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 17, p. 5517, doi. 10.3390/molecules27175517

By:

Wang, Haibo;
Tang, Senling;
Zhang, Guoqing;
Pan, Yang;
Jiao, Wei;
Shao, Huawu

Publication type:

Article

Multivalent Pyrrolidine Iminosugars: Synthesis and Biological Relevance.

Published in:

Molecules, 2022, v. 27, n. 17, p. 5420, doi. 10.3390/molecules27175420

By:

Wang, Yali;
Xiao, Jian;
Meng, Aiguo;
Liu, Chunyan

Publication type:

Article

Bambus[4,6]urils as Dual Scaffolds for Multivalent Iminosugar Presentation and Ion Transport: Access to Unprecedented Glycosidase-Directed Anion Caging Agents.

Published in:

Molecules, 2022, v. 27, n. 15, p. 4772, doi. 10.3390/molecules27154772

By:

Lafosse, Marine;
Liang, Yan;
Schneider, Jérémy P.;
Cartier, Elise;
Bodlenner, Anne;
Compain, Philippe;
Heck, Marie-Pierre

Publication type:

Article

Synthesis of a New β-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis.

Published in:

Molecules, 2022, v. 27, n. 13, p. 4008, doi. 10.3390/molecules27134008

By:

Clemente, Francesca;
Martínez-Bailén, Macarena;
Matassini, Camilla;
Morrone, Amelia;
Falliano, Silvia;
Caciotti, Anna;
Paoli, Paolo;
Goti, Andrea;
Cardona, Francesca

Publication type:

Article

A Convenient Approach towards the Synthesis of ADMDP Type Iminosugars and Nojirimycin Derivatives from Sugar-Derived Lactams.

Published in:

Molecules, 2021, v. 26, n. 18, p. 5459, doi. 10.3390/molecules26185459

By:

Szcześniak, Piotr;
Grzeszczyk, Barbara;
Furman, Bartłomiej

Publication type:

Article

Synthesis and Evaluation of Novel Iminosugars Prepared from Natural Amino Acids.

Published in:

Molecules, 2021, v. 26, n. 2, p. 394, doi. 10.3390/molecules26020394

By:

Puet, Alejandro;
Domínguez, Gema;
Cañada, Francisco Javier;
Pérez-Castells, Javier;
Garrido, Narciso M.

Publication type:

Article

Synthesis of "All-Cis" Trihydroxypiperidines from a Carbohydrate-Derived Ketone: Hints for the Design of New β-Gal and GCase Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 19, p. 4526, doi. 10.3390/molecules25194526

By:

Davighi, Maria Giulia;
Clemente, Francesca;
Matassini, Camilla;
Morrone, Amelia;
Goti, Andrea;
Martínez-Bailén, Macarena;
Cardona, Francesca;
Piantanida, Ivo;
Csuk, René;
Jacob, Claus;
Oyelere, Adegboyega K.

Publication type:

Article

New Frontiers on Human Safe Insecticides and Fungicides: An Opinion on Trehalase Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 13, p. 3013, doi. 10.3390/molecules25133013

By:

Matassini, Camilla;
Parmeggiani, Camilla;
Cardona, Francesca;
Song, Baoan

Publication type:

Article

Selective Targeting of the Interconversion between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors.

Published in:

Molecules, 2019, v. 24, n. 2, p. 354, doi. 10.3390/molecules24020354

By:

Baudoin-Dehoux, Cécile;
Castellan, Tessa;
Rodriguez, Frédéric;
Rives, Arnaud;
Stauffert, Fabien;
Garcia, Virginie;
Levade, Thierry;
Compain, Philippe;
Génisson, Yves;
Nefzi, Adel

Publication type:

Article

Probing the Inhibitor versus Chaperone Properties of sp2-Iminosugars towards Human β-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease.

Published in:

Molecules, 2018, v. 23, n. 4, p. 927, doi. 10.3390/molecules23040927

By:

Mena-Barragán, Teresa;
García-Moreno, M. Isabel;
Sevšek, Alen;
Okazaki, Tetsuya;
Nanba, Eiji;
Higaki, Katsumi;
Martin, Nathaniel I.;
Pieters, Roland J.;
Fernández, José M. García;
Mellet, Carmen Ortiz

Publication type:

Article

An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars.

Published in:

Molecules, 2013, v. 18, n. 5, p. 6021, doi. 10.3390/molecules18056021

By:

Hui Zhao;
Wen-Bo Zhao;
Jian-She Zhu;
Yue-Mei Jia;
Chu-Yi Yu

Publication type:

Article

Protecting-Group-Free Synthesis of 2-Deoxy-Aza-Sugars.

Published in:

Molecules, 2009, v. 14, n. 12, p. 5298, doi. 10.3390/molecules14125298

By:

Dangerfield, Emma Marie;
Plunkett, Catherine Heather;
Stocker, Bridget Louise;
Timmer, Mattie Simon Maria

Publication type:

Article

Regulation of spirocyst discharge in the model sea anemone, Nematostella vectensis.

Published in:

Marine Biology, 2010, v. 157, n. 5, p. 1041, doi. 10.1007/s00227-009-1384-x

By:

Krayesky, Sherry L.;
Mahoney, Janna L.;
Kinler, Katherine M.;
Peltier, Stacey;
Calais, Warnesha;
Allaire, Kate;
Watson, Glen M.

Publication type:

Article

Synthesis of New Iminosugar Derivatives Based on (S)-(1,2,3,6-Tetrahydropyridazin-3-yl)methanol.

Published in:

Russian Journal of Organic Chemistry, 2019, v. 55, n. 12, p. 1975, doi. 10.1134/S1070428019120297

By:

Axundova, F. N.;
Kurbanova, M. M.;
Huseynzada, A. E.;
Alves, M. J.

Publication type:

Article

Synthesis of Glycosylated 1‐Deoxynojirimycins Starting from Natural and Synthetic Disaccharides.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 1, p. 118, doi. 10.1002/ejoc.201801461

By:

Liu, Bing;
van Mechelen, Jeanine;
van den Berg, Richard J. B. H. N.;
van den Nieuwendijk, Adrianus M. C. H.;
Aerts, Johannes M. F. G.;
van der Marel, Gijsbert A.;
Codée, Jeroen D. C.;
Overkleeft, Herman S.

Publication type:

Article

2‐Acetamido‐2‐deoxy‐l‐iminosugar C‐Alkyl and C‐Aryl Glycosides: Synthesis and Glycosidase Inhibition.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 40, p. 5477, doi. 10.1002/ejoc.201800678

By:

Fontelle, Nathalie;
Yamamoto, Arisa;
Arda, Ana;
Jiménez‐barbero, Jesús;
Kato, Atsushi;
Désiré, Jérôme;
Blériot, Yves

Publication type:

Article

On the Asymmetric Induction in Proline-Catalyzed Aldol Reactions: Reagent-Controlled Addition Reactions of 2,2- Dimethyl-1,3-dioxane-5-one to Acyclic Chiral α-Branched Aldehydes.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 41, p. 6146, doi. 10.1002/ejoc.201701073

By:

Marjanovic Trajkovic, Jasna;
Milanovic, Vesna;
Ferjancic, Zorana;
Saicic, Radomir N.

Publication type:

Article

Triazole-Linked Iminosugars and Aromatic Systems as Simplified UDP-Galf Mimics: Synthesis and Preliminary Evaluation as Galf-Transferase Inhibitors.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 41, p. 6192, doi. 10.1002/ejoc.201701283

By:

Cocaud, Chloé;
Maujoin, Audrey;
Zheng, Ruixiang B.;
Lowary, Todd L.;
Rodrigues, Nuno;
Percina, Nathalie;
Chartier, Agnes;
Buron, Frédéric;
Routier, Sylvain;
Nicolas, Cyril;
Martin, Olivier R.

Publication type:

Article

A Click Ligation Based on SuFEx for the Metal-Free Synthesis of Sugar and Iminosugar Clusters.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 30, p. 5102, doi. 10.1002/ejoc.201600732

By:

Zelli, Renaud;
Tommasone, Stefano;
Dumy, Pascal;
Marra, Alberto;
Dondoni, Alessandro

Publication type:

Article

Front Cover: A Click Ligation Based on SuFEx for the Metal-Free Synthesis of Sugar and Iminosugar Clusters (Eur. J. Org. Chem. 30/2016).

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 30, p. 5055, doi. 10.1002/ejoc.201670301

By:

Zelli, Renaud;
Tommasone, Stefano;
Dumy, Pascal;
Marra, Alberto;
Dondoni, Alessandro

Publication type:

Article

Diversity-Oriented Synthesis and Biological Evaluation of Iminosugars from Unprotected 2-Deoxy- d-ribose.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 21, p. 3642, doi. 10.1002/ejoc.201600459

By:

Malinowski, Maciej;
Rowicki, Tomasz;
Guzik, Patrycja;
Wielechowska, Monika;
Sobiepanek, Anna;
Sas, Wojciech

Publication type:

Article

Unprotected Xylose-Derived Nitrone in Stereodivergent Synthesis of 4-Hydroxypiperidine Enantiomers: Weak Lewis Acid Induced Alteration of Stereochemistry in 1,3-Dipolar Cycloaddition.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 7, p. 1533, doi. 10.1002/ejoc.201403410

By:

Rowicki, Tomasz;
Malinowski, Maciej;
Gryszel, Maciej;
Czerwińska, Karolina;
Madura, Izabela;
Mironiuk‐Puchalska, Ewa;
Koszytkowska‐Stawińska, Mariola;
Sas, Wojciech

Publication type:

Article

Perfluoroalkylation of Nitrones for the Synthesis of a Series of Fucosidase Inhibitors.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 6, p. 1198, doi. 10.1002/ejoc.201403485

By:

Paszkowska, Jadwiga;
Fernandez, Olalla Novo;
Wandzik, Ilona;
Boudesoque, Stéphanie;
Dupont, Laurent;
Plantier‐Royon, Richard;
Behr, Jean‐Bernard

Publication type:

Article

Stereoselective Access to the β-D-N-Acetylhexosaminyl-(1 → 4)-1-deoxy-D-nojirimycin Disaccharide Series Avoiding the Glycosylation Reaction.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 29, p. 6527, doi. 10.1002/ejoc.201402555

By:

Guazzelli, Lorenzo;
Catelani, Giorgio;
D'Andrea, Felicia;
Gragnani, Tiziana;
Griselli, Alessio

Publication type:

Article

Graphical Abstract: Eur. J. Org. Chem. 25/2014.

Published in:: European Journal of Organic Chemistry, 2014, v. 2014, n. 25, p. 5383, doi. 10.1002/ejoc.201490071
Publication type:: Article

A Convergent Strategy for the Synthesis of Second-Generation Iminosugar Clusters Using 'Clickable' Trivalent Dendrons.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 9, p. 1866, doi. 10.1002/ejoc.201301583

By:

Joosten, Antoine;
Schneider, Jérémy P.;
Lepage, Mathieu L.;
Tarnus, Céline;
Bodlenner, Anne;
Compain, Philippe

Publication type:

Article

Exploring a Multivalent Approach to α- L-Fucosidase Inhibition.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 32, p. 7328, doi. 10.1002/ejoc.201300878

By:

Moreno‐Clavijo, Elena;
Carmona, Ana T.;
Moreno‐Vargas, Antonio J.;
Molina, Lidia;
Wright, Daniel W.;
Davies, Gideon J.;
Robina, Inmaculada

Publication type:

Article

Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167018

By:

Miller, Joanna L.;
Spiro, Simon G.;
Dowall, Stuart D.;
Taylor, Irene;
Rule, Antony;
Alonzi, Dominic S.;
Sayce, Andrew C.;
Wright, Edward;
Bentley, Emma M.;
Thom, Ruth;
Hall, Graham;
Dwek, Raymond A.;
Hewson, Roger;
Zitzmann, Nicole

Publication type:

Article

Rapid identification of miglitol and its isomers by electrospray ionization tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2016, v. 30, p. 155, doi. 10.1002/rcm.7618

By:

Yin, Qiuhong;
Wang, Lin;
Sun, Cuirong

Publication type:

Article

Determination of d-fagomine in buckwheat and mulberry by cation exchange HPLC/ESI-Q-MS.

Published in:

Analytical & Bioanalytical Chemistry, 2012, v. 402, n. 5, p. 1953, doi. 10.1007/s00216-011-5639-2

By:

Amézqueta, Susana;
Galán, Esther;
Fuguet, Elisabet;
Carrascal, Montserrat;
Abián, Joaquín;
Torres, Josep

Publication type:

Article

The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine.

Published in:

Glycobiology, 2010, v. 20, n. 5, p. 500, doi. 10.1093/glycob/cwp202

By:

Macchi, Beatrice;
Minutolo, Antonella;
Grelli, Sandro;
Cardona, Francesca;
Cordero, Franca M.;
Mastino, Antonio;
Brandi, Alberto

Publication type:

Article

A Facile Synthesis of Pyrrolidine-based Iminosugars as Potential Alpha-Glucosidase Inhibitors.

Published in:

Oriental Journal of Chemistry, 2020, v. 36, n. 2, p. 309, doi. 10.13005/ojc/360214

By:

BACHO, MUHAMAD ZULFAQAR;
MOHAMMAT, MOHD FAZLI;
SHAAMERI, ZURINA;
WIBOWO, AGUSTONO;
KAMARULZAMAN, FIRDAUS;
HAMZAH, AHMAD SAZALI

Publication type:

Article

One‐Pot Synthesis of Semi‐Saturated Fused Polycyclic Iminosugars by a Diels‐Alder Reaction.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 1, p. 1, doi. 10.1002/ejoc.202401005

By:

Xie, Song;
Wu, Jilai;
Zhou, Likai;
Wei, Chao;
Li, Xiaoliu;
Chen, Hua

Publication type:

Article

Stable Ditriflates of D‐Glucose in the Synthesis of Iminosugars and Polyhydroxylated Pipecolic Acids.

Published in:

European Journal of Organic Chemistry, 2024, v. 27, n. 42, p. 1, doi. 10.1002/ejoc.202400395

By:

Balo, Rosalino;
Fernández, Andrés;
Reza, David;
López, Pablo;
Fleet, George W. J.;
Estévez, Ramón J.;
Estévez, Juan C.

Publication type:

Article

One‐Pot Synthesis of Fused Tetrahydroquinoline‐Iminosugar Derivatives.

Published in:

European Journal of Organic Chemistry, 2023, v. 26, n. 44, p. 1, doi. 10.1002/ejoc.202300915

By:

Wu, Jilai;
Xie, Song;
Xu, Xin;
Zhou, Ziyi;
Zhou, Likai;
Wei, Chao;
Li, Xiaoliu;
Wu, Chen;
Chen, Hua

Publication type:

Article

Amphiphilic Iminosugar Pharmacological Chaperones towards β‐Glucocerebrosidase: Self‐Assembly and Biological Activity.

Published in:

European Journal of Organic Chemistry, 2023, v. 26, n. 11, p. 1, doi. 10.1002/ejoc.202200911

By:

Vanni, Costanza;
Cardona, Francesca;
Clemente, Francesca;
Morrone, Amelia;
Raudino, Martina;
Ambrosi, Moira;
Lo Nostro, Pierandrea;
Matassini, Camilla

Publication type:

Article

Organocatalytic Synthesis and Anti‐Trypanosomal Activity Evaluation of L‐Pentofuranose‐Mimetic Iminosugars.

Published in:

European Journal of Organic Chemistry, 2022, v. 2022, n. 34, p. 1, doi. 10.1002/ejoc.202200636

By:

Mesa, Juan M.;
Comini, Marcelo A.;
Dibello, Estefanía;
Gamenara, Daniela

Publication type:

Article

Combining Organocatalyzed Aldolization and Reductive Amination: An Efficient Reaction Sequence for the Synthesis of Iminosugars.

Published in:

European Journal of Organic Chemistry, 2021, v. 2021, n. 22, p. 3241, doi. 10.1002/ejoc.202100398

By:

Ferjancic, Zorana;
Saicic, Radomir N.

Publication type:

Article

Conformationally Restricted Oxazolidin‐2‐one Fused Bicyclic Iminosugars as Potential Glycosidase Inhibitors.

Published in:

European Journal of Organic Chemistry, 2020, v. 2020, n. 38, p. 6109, doi. 10.1002/ejoc.202001053

By:

Domingues, Maria;
Jaszczyk, Justyna;
Ismael, Maria Isabel;
Figueiredo, José Albertino;
Daniellou, Richard;
Lafite, Pierre;
Schuler, Marie;
Tatibouët, Arnaud

Publication type:

Article

Reductive Amination Routes in the Synthesis of Piperidine IminoSugars.

Published in:

European Journal of Organic Chemistry, 2020, v. 2020, n. 29, p. 4447, doi. 10.1002/ejoc.201901840

By:

Clemente, Francesca;
Matassini, Camilla;
Cardona, Francesca

Publication type:

Article

A Route to 1‐Deoxynojirimycin and 1‐Deoxymannojirimycin Derivatives with Quaternary Centers Adjacent to the Ring Nitrogen from Methyl α‐d‐Mannopyranoside.

Published in:

European Journal of Organic Chemistry, 2020, v. 2020, n. 16, p. 2389, doi. 10.1002/ejoc.201901875

By:

Chadda, Rekha;
Murphy, Paul V.

Publication type:

Article

Studies for the Multimerization of DAB‐1‐Based Iminosugars through Iteration of the Nitrone Cycloaddition/Ring‐Opening/Allylation Sequence.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 30, p. 4897, doi. 10.1002/ejoc.201900823

By:

Matassini, Camilla;
D'Adamio, Giampiero;
Vanni, Costanza;
Goti, Andrea;
Cardona, Francesca

Publication type:

Article

C‐Branched Imino Sugars: Synthesis and Biological Relevance.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 30, p. 4765, doi. 10.1002/ejoc.201900605

By:

Dehoux‐Baudoin, Cécile;
Génisson, Yves

Publication type:

Article