Works matching DE "IMINOSUGARS"

Results: 114

A Biocatalytic Cascade for the Valorization of Sugars.

Published in:

ChemCatChem, 2025, v. 17, n. 12, p. 1, doi. 10.1002/cctc.202500110

By:

Yeow, Kathryn;
Martin, Aoife;
Muldoon, Jimmy;
Haarr, Marianne Bore;
O'Reilly, Elaine

Publication type:

Article

The iminosugars celgosivir, castanospermine and UV-4 inhibit SARS-CoV-2 replication.

Published in:

Glycobiology, 2021, v. 31, n. 4, p. 378, doi. 10.1093/glycob/cwaa091

By:

Clarke, Elizabeth C;
Nofchissey, Robert A;
Ye, Chunyan;
Bradfute, Steven B

Publication type:

Article

The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine.

Published in:

Glycobiology, 2010, v. 20, n. 5, p. 500, doi. 10.1093/glycob/cwp202

By:

Macchi, Beatrice;
Minutolo, Antonella;
Grelli, Sandro;
Cardona, Francesca;
Cordero, Franca M.;
Mastino, Antonio;
Brandi, Alberto

Publication type:

Article

Regulation of spirocyst discharge in the model sea anemone, Nematostella vectensis.

Published in:

Marine Biology, 2010, v. 157, n. 5, p. 1041, doi. 10.1007/s00227-009-1384-x

By:

Krayesky, Sherry L.;
Mahoney, Janna L.;
Kinler, Katherine M.;
Peltier, Stacey;
Calais, Warnesha;
Allaire, Kate;
Watson, Glen M.

Publication type:

Article

A Facile Synthesis of Pyrrolidine-based Iminosugars as Potential Alpha-Glucosidase Inhibitors.

Published in:

Oriental Journal of Chemistry, 2020, v. 36, n. 2, p. 309, doi. 10.13005/ojc/360214

By:

BACHO, MUHAMAD ZULFAQAR;
MOHAMMAT, MOHD FAZLI;
SHAAMERI, ZURINA;
WIBOWO, AGUSTONO;
KAMARULZAMAN, FIRDAUS;
HAMZAH, AHMAD SAZALI

Publication type:

Article

Rapid identification of miglitol and its isomers by electrospray ionization tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2016, v. 30, p. 155, doi. 10.1002/rcm.7618

By:

Yin, Qiuhong;
Wang, Lin;
Sun, Cuirong

Publication type:

Article

Potent and Selective Cell‐Active Iminosugar Inhibitors of Human α‐N‐Acetylgalactosaminidase (α‐NAGAL).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 44, p. 1, doi. 10.1002/chem.202300982

By:

Ashmus, Roger A.;
Wang, Yang;
González‐Cuesta, Manuel;
King, Dustin T.;
Tiet, Ben;
Chen, Xi;
Zhu, Yanping;
Kirk, Bryce;
García Fernandez, José M.;
Ortiz Mellet, Carmen;
Britton, Robert;
Vocadlo, David J.

Publication type:

Article

Frontispiece: Approaches to the Synthesis of Perfluoroalkyl‐Modified Carbohydrates and Derivatives: Thiosugars, Iminosugars, and Tetrahydro(thio)pyrans.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 29, p. 1, doi. 10.1002/chem.202182961

By:

Uhrig, María Laura;
Mora Flores, Erwin W.;
Postigo, Al

Publication type:

Article

Approaches to the Synthesis of Perfluoroalkyl‐Modified Carbohydrates and Derivatives: Thiosugars, Iminosugars, and Tetrahydro(thio)pyrans.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 29, p. 7813, doi. 10.1002/chem.202005229

By:

Uhrig, María Laura;
Mora Flores, Erwin W.;
Postigo, Al

Publication type:

Article

Influence of Side Chain Conformation on the Activity of Glycosidase Inhibitors.

Published in:

Angewandte Chemie, 2023, v. 135, n. 8, p. 1, doi. 10.1002/ange.202217809

By:

Tseng, Po‐Sen;
Ande, Chennaiah;
Moremen, Kelley W.;
Crich, David

Publication type:

Article

Cyclisations and Strategies for Stereoselective Synthesis of Piperidine Iminosugars.

Published in:

Chemical Record, 2021, v. 21, n. 11, p. 2958, doi. 10.1002/tcr.202100221

By:

Dhara, Debashis;
Dhara, Ashis;
Bennett, Jack;
Murphy, Paul V.

Publication type:

Article

Glycomimetics and Glycoconjugates in Drug Discovery.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 3, p. 323, doi. 10.3390/ph17030323

By:

Xavier, Nuno M.;
Andreana, Peter R.

Publication type:

Article

Synthesis and Glycosidase Inhibition Properties of Calix[8]arene-Based Iminosugar Click Clusters.

Published in:

Pharmaceuticals (14248247), 2020, v. 13, n. 11, p. 366, doi. 10.3390/ph13110366

By:

Schneider, Jérémy P.;
Tommasone, Stefano;
Della Sala, Paolo;
Gaeta, Carmine;
Talotta, Carmen;
Tarnus, Céline;
Neri, Placido;
Bodlenner, Anne;
Compain, Philippe

Publication type:

Article

Iminosugars: Effects of Stereochemistry, Ring Size, and N-Substituents on Glucosidase Activities.

Published in:

Pharmaceuticals (14248247), 2019, v. 12, n. 3, p. 108, doi. 10.3390/ph12030108

By:

Zamoner, Luís O. B.;
Aragão-Leoneti, Valquiria;
Carvalho, Ivone

Publication type:

Article

Synthesis of novel azasugar-containing 2'β-C-Me 9-deaza nucleosides as potential anti-hepatitis C virus agents.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2023, v. 42, n. 4, p. 317, doi. 10.1080/15257770.2022.2142609

By:

Kotian, Pravin L.;
Wu, Minwan;
Ghosh, Ajit;
Polach, Kevin J.;
El-Kattan, Yahya;
Kumar, V. Satish;
Lin, Tsu-Hsing;
Cheng, Xiaogang;
Bantia, Shanta;
Raman, Krishnan;
Chand, Pooran;
Babu, Yarlagadda S.

Publication type:

Article

Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 138, doi. 10.1080/14756366.2020.1847101

By:

Ahuja-Casarín, Ana I.;
Merino-Montiel, Penélope;
Vega-Baez, José Luis;
Montiel-Smith, Sara;
Fernandes, Miguel X.;
Lagunes, Irene;
Maya, Inés;
Padrón, José M.;
López, Óscar;
Fernández-Bolaños, José G.

Publication type:

Article

Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167018

By:

Miller, Joanna L.;
Spiro, Simon G.;
Dowall, Stuart D.;
Taylor, Irene;
Rule, Antony;
Alonzi, Dominic S.;
Sayce, Andrew C.;
Wright, Edward;
Bentley, Emma M.;
Thom, Ruth;
Hall, Graham;
Dwek, Raymond A.;
Hewson, Roger;
Zitzmann, Nicole

Publication type:

Article

Synthesis and Therapeutic Applications of Iminosugars in Cystic Fibrosis.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 9, p. 3353, doi. 10.3390/ijms21093353

By:

Esposito, Anna;
D'Alonzo, Daniele;
De Fenza, Maria;
De Gregorio, Eliana;
Tamanini, Anna;
Lippi, Giuseppe;
Dechecchi, Maria Cristina;
Guaragna, Annalisa

Publication type:

Article

In Planta Preliminary Screening of ER Glycoprotein Folding Quality Control (ERQC) Modulators.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 7, p. 2135, doi. 10.3390/ijms19072135

By:

Marti, Lucia;
Lia, Andrea;
Reca, Ida-Barbara;
Santino, Angelo;
Zitzmann, Nicole;
Roversi, Pietro

Publication type:

Article

Asymmetric total synthesis of L-allo-1-deoxynojirimycin.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2016, p. 137, doi. 10.3998/ark.5550190.p009.295

By:

Chavan, Subhash P.;
Dumare, Nilesh B.;
Pawar, Kailash P.;
Chavan, Prakash N.;
Khairnar, Lalit

Publication type:

Article

Longitudinal changes in cerebellar and subcortical volumes in adult-onset Niemann-Pick disease type C patients treated with miglustat.

Published in:

Journal of Neurology, 2015, v. 262, n. 9, p. 2106, doi. 10.1007/s00415-015-7819-z

By:

Bowman, Elizabeth;
Walterfang, Mark;
Abel, Larry;
Desmond, Patricia;
Fahey, Michael;
Velakoulis, Dennis

Publication type:

Article

Food Iminosugars and Related Synthetic Derivatives Shift Energy Metabolism and Induce Structural Changes in Colon Cancer Cell Lines.

Published in:

Foods, 2025, v. 14, n. 10, p. 1713, doi. 10.3390/foods14101713

By:

Montebugnoli, Thomas;
Grootaert, Charlotte;
Bordoni, Alessandra;
Rajković, Andreja;
Alderweireldt, Elien;
Rombaut, Jeltien;
De Maeseneire, Sofie L.;
Van Camp, John;
De Mol, Maarten Lieven

Publication type:

Article

Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184517

By:

Ramos-Morales, Eva;
de la Fuente, Gabriel;
Nash, Robert J.;
Braganca, Radek;
Duval, Stephane;
Bouillon, Marc E.;
Lahmann, Martina;
Newbold, C. Jamie

Publication type:

Article

2‐Acetamido‐2‐deoxy‐l‐iminosugar C‐Alkyl and C‐Aryl Glycosides: Synthesis and Glycosidase Inhibition.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 40, p. 5477, doi. 10.1002/ejoc.201800678

By:

Fontelle, Nathalie;
Yamamoto, Arisa;
Arda, Ana;
Jiménez‐barbero, Jesús;
Kato, Atsushi;
Désiré, Jérôme;
Blériot, Yves

Publication type:

Article

On the Asymmetric Induction in Proline-Catalyzed Aldol Reactions: Reagent-Controlled Addition Reactions of 2,2- Dimethyl-1,3-dioxane-5-one to Acyclic Chiral α-Branched Aldehydes.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 41, p. 6146, doi. 10.1002/ejoc.201701073

By:

Marjanovic Trajkovic, Jasna;
Milanovic, Vesna;
Ferjancic, Zorana;
Saicic, Radomir N.

Publication type:

Article

Triazole-Linked Iminosugars and Aromatic Systems as Simplified UDP-Galf Mimics: Synthesis and Preliminary Evaluation as Galf-Transferase Inhibitors.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 41, p. 6192, doi. 10.1002/ejoc.201701283

By:

Cocaud, Chloé;
Maujoin, Audrey;
Zheng, Ruixiang B.;
Lowary, Todd L.;
Rodrigues, Nuno;
Percina, Nathalie;
Chartier, Agnes;
Buron, Frédéric;
Routier, Sylvain;
Nicolas, Cyril;
Martin, Olivier R.

Publication type:

Article

A Click Ligation Based on SuFEx for the Metal-Free Synthesis of Sugar and Iminosugar Clusters.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 30, p. 5102, doi. 10.1002/ejoc.201600732

By:

Zelli, Renaud;
Tommasone, Stefano;
Dumy, Pascal;
Marra, Alberto;
Dondoni, Alessandro

Publication type:

Article

Front Cover: A Click Ligation Based on SuFEx for the Metal-Free Synthesis of Sugar and Iminosugar Clusters (Eur. J. Org. Chem. 30/2016).

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 30, p. 5055, doi. 10.1002/ejoc.201670301

By:

Zelli, Renaud;
Tommasone, Stefano;
Dumy, Pascal;
Marra, Alberto;
Dondoni, Alessandro

Publication type:

Article

Diversity-Oriented Synthesis and Biological Evaluation of Iminosugars from Unprotected 2-Deoxy- d-ribose.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 21, p. 3642, doi. 10.1002/ejoc.201600459

By:

Malinowski, Maciej;
Rowicki, Tomasz;
Guzik, Patrycja;
Wielechowska, Monika;
Sobiepanek, Anna;
Sas, Wojciech

Publication type:

Article

Unprotected Xylose-Derived Nitrone in Stereodivergent Synthesis of 4-Hydroxypiperidine Enantiomers: Weak Lewis Acid Induced Alteration of Stereochemistry in 1,3-Dipolar Cycloaddition.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 7, p. 1533, doi. 10.1002/ejoc.201403410

By:

Rowicki, Tomasz;
Malinowski, Maciej;
Gryszel, Maciej;
Czerwińska, Karolina;
Madura, Izabela;
Mironiuk‐Puchalska, Ewa;
Koszytkowska‐Stawińska, Mariola;
Sas, Wojciech

Publication type:

Article

Perfluoroalkylation of Nitrones for the Synthesis of a Series of Fucosidase Inhibitors.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 6, p. 1198, doi. 10.1002/ejoc.201403485

By:

Paszkowska, Jadwiga;
Fernandez, Olalla Novo;
Wandzik, Ilona;
Boudesoque, Stéphanie;
Dupont, Laurent;
Plantier‐Royon, Richard;
Behr, Jean‐Bernard

Publication type:

Article

Stereoselective Access to the β-D-N-Acetylhexosaminyl-(1 → 4)-1-deoxy-D-nojirimycin Disaccharide Series Avoiding the Glycosylation Reaction.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 29, p. 6527, doi. 10.1002/ejoc.201402555

By:

Guazzelli, Lorenzo;
Catelani, Giorgio;
D'Andrea, Felicia;
Gragnani, Tiziana;
Griselli, Alessio

Publication type:

Article

Graphical Abstract: Eur. J. Org. Chem. 25/2014.

Published in:: European Journal of Organic Chemistry, 2014, v. 2014, n. 25, p. 5383, doi. 10.1002/ejoc.201490071
Publication type:: Article

A Convergent Strategy for the Synthesis of Second-Generation Iminosugar Clusters Using 'Clickable' Trivalent Dendrons.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 9, p. 1866, doi. 10.1002/ejoc.201301583

By:

Joosten, Antoine;
Schneider, Jérémy P.;
Lepage, Mathieu L.;
Tarnus, Céline;
Bodlenner, Anne;
Compain, Philippe

Publication type:

Article

Exploring a Multivalent Approach to α- L-Fucosidase Inhibition.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 32, p. 7328, doi. 10.1002/ejoc.201300878

By:

Moreno‐Clavijo, Elena;
Carmona, Ana T.;
Moreno‐Vargas, Antonio J.;
Molina, Lidia;
Wright, Daniel W.;
Davies, Gideon J.;
Robina, Inmaculada

Publication type:

Article

[1] Miglustat in patients with Niemann-Pick disease type C (NP-C): a multicenter observational retrospective cohort study/[2] Long-term miglustat therapy in children with Niemann-Pick disease type C/[3] Miglustat in adult and juvenile patients with Niemann-Pick disease type C: long-term data from a clinical trial.

Published in:: Current Medical Literature: Lysosomal Storage Disease, 2011, v. 9, n. 1, p. 29
Publication type:: Article

Pharmacological enhancement of mutated alpha-glucosidase activity in fibroblasts from patients with Pompe disease.

Published in:: Current Medical Literature: Lysosomal Storage Disease, 2007, v. 7, n. 2, p. 57
Publication type:: Article

Use of Small Molecules for the Treatment of Lysosomal Storage Diseases.

Published in:

Current Medical Literature: Lysosomal Storage Disease, 2007, v. 7, n. 2, p. 33

By:

Beck, Michael

Publication type:

Article

Novel nucleoside analogs tethered on (3 R,4 R)-4-(hydroxymethyl)pyrrolidin-3-ol.

Published in:

Journal of the Iranian Chemical Society, 2015, v. 12, n. 4, p. 655, doi. 10.1007/s13738-014-0524-5

By:

Amici, Adolfo;
Martelli, Gianluca;
Orena, Mario;
Rinaldi, Samuele

Publication type:

Article

Lucerastat, an iminosugar with potential as substrate reduction therapy for glycolipid storage disorders: safety, tolerability, and pharmacokinetics in healthy subjects.

Published in:

2017

By:

Guérard, N.;
Morand, O.;
Dingemanse, J.

Publication type:

journal article

Stereoselective synthesis of 1-deoxynojirimycin, D-glucono-δ-lactam and D-altrono-δ-lactam from a common chiral intermediate derived from D-mannitol.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2012, p. 287

By:

Ravinder, Mettu;
Reddy, Thatikonda Narendar;
Mahendar, Budde;
Rao, Vaidya Jayathirtha

Publication type:

Article

Iminosugars: Promising therapeutics for influenza infection.

Published in:

Critical Reviews in Microbiology, 2017, v. 43, n. 5, p. 521, doi. 10.1080/1040841X.2016.1242868

By:

Tyrrell, Beatrice Ellen;
Sayce, Andrew Cameron;
Warfield, Kelly Lyn;
Miller, Joanna Louise;
Zitzmann, Nicole

Publication type:

Article

Giant Glycosidase Inhibitors: First‐ and Second‐Generation Fullerodendrimers with a Dense Iminosugar Shell.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 10, p. 2483, doi. 10.1002/chem.201705600

By:

Nierengarten, Jean‐François;
Schneider, Jérémy P.;
Trinh, Thi Minh Nguyet;
Joosten, Antoine;
Holler, Michel;
Lepage, Mathieu L.;
Bodlenner, Anne;
García‐Moreno, M. Isabel;
Ortiz Mellet, Carmen;
Compain, Philippe

Publication type:

Article

Frontispiece: The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 26, p. n/a, doi. 10.1002/chem.201782663

By:

García ‐ Moreno, M. Isabel;
Ortega ‐ Caballero, Fernando;
Rísquez ‐ Cuadro, Rocío;
Ortiz Mellet, Carmen;
García Fernández, José M.

Publication type:

Article

A Short and Efficient Synthesis of Iminosugar 2-Acyl Indolizidine.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 3, p. 533, doi. 10.1002/chem.201604376

By:

Chinthapally, Kiran;
Karthik, Reshamina;
Senthilkumar, Soundararasu;
Baskaran, Sundarababu

Publication type:

Article

Diversity-oriented synthesis of glycomimetics.

Published in:

Communications Chemistry, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42004-021-00520-3

By:

Meanwell, Michael;
Fehr, Gaelen;
Ren, Weiwu;
Adluri, Bharanishashank;
Rose, Victoria;
Lehmann, Johannes;
Silverman, Steven M.;
Rowshanpour, Rozhin;
Adamson, Christopher;
Bergeron-Brlek, Milan;
Foy, Hayden;
Challa, Venugopal Rao;
Campeau, Louis-Charles;
Dudding, Travis;
Britton, Robert

Publication type:

Article

One‐Pot Synthesis of Semi‐Saturated Fused Polycyclic Iminosugars by a Diels‐Alder Reaction.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 1, p. 1, doi. 10.1002/ejoc.202401005

By:

Xie, Song;
Wu, Jilai;
Zhou, Likai;
Wei, Chao;
Li, Xiaoliu;
Chen, Hua

Publication type:

Article

Stable Ditriflates of D‐Glucose in the Synthesis of Iminosugars and Polyhydroxylated Pipecolic Acids.

Published in:

European Journal of Organic Chemistry, 2024, v. 27, n. 42, p. 1, doi. 10.1002/ejoc.202400395

By:

Balo, Rosalino;
Fernández, Andrés;
Reza, David;
López, Pablo;
Fleet, George W. J.;
Estévez, Ramón J.;
Estévez, Juan C.

Publication type:

Article

One‐Pot Synthesis of Fused Tetrahydroquinoline‐Iminosugar Derivatives.

Published in:

European Journal of Organic Chemistry, 2023, v. 26, n. 44, p. 1, doi. 10.1002/ejoc.202300915

By:

Wu, Jilai;
Xie, Song;
Xu, Xin;
Zhou, Ziyi;
Zhou, Likai;
Wei, Chao;
Li, Xiaoliu;
Wu, Chen;
Chen, Hua

Publication type:

Article

Amphiphilic Iminosugar Pharmacological Chaperones towards β‐Glucocerebrosidase: Self‐Assembly and Biological Activity.

Published in:

European Journal of Organic Chemistry, 2023, v. 26, n. 11, p. 1, doi. 10.1002/ejoc.202200911

By:

Vanni, Costanza;
Cardona, Francesca;
Clemente, Francesca;
Morrone, Amelia;
Raudino, Martina;
Ambrosi, Moira;
Lo Nostro, Pierandrea;
Matassini, Camilla

Publication type:

Article