Works matching DE "IKAPPA B kinase"

Results: 38

Compressive mechanical stress may activate IKK-NF-κB through proinflammatory cytokines in MC3T3-E1 cells.

Published in:

Biotechnology Letters, 2015, v. 37, n. 9, p. 1729, doi. 10.1007/s10529-015-1849-6

By:

Lu, Ying;
Zheng, Qinghua;
Lu, Wanlu;
Yue, Junli;
Zhou, Wei;
Zhou, Xuedong;
Zhang, Lan;
Huang, Dingming

Publication type:

Article

Effect of Echinacea Polysaccharide on Secretion of IkB-α mRNA by IEC-6 Injured by LPS.

Published in:

Agricultural Biotechnology (2164-4993), 2017, v. 6, n. 1, p. 31

By:

Qiumei SHI;
Yanying ZHANG;
Qinghui JIA;
Huiyuan ZHAO;
Minghe YU;
Guohui YU;
Jiwei An

Publication type:

Article

PM<sub>2.5</sub> stimulated the release of cytokines from BEAS-2B cells through activation of IKK/NF-κB pathway.

Published in:

Human & Experimental Toxicology, 2019, v. 38, n. 3, p. 311, doi. 10.1177/0960327118802628

By:

Wang, J.;
Zhang, W. J.;
Xiong, W.;
Lu, W. H.;
Zheng, H. Y.;
Zhou, X.;
Yuan, J.

Publication type:

Article

Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis.

Published in:

2017

By:

Williams, Virginie;
Grosset, Andrée-Anne;
Cuervo, Natalia Zamorano;
St-Pierre, Yves;
Sylvestre, Marie-Pierre;
Gaboury, Louis;
Grandvaux, Nathalie;
Zamorano Cuervo, Natalia

Publication type:

journal article

HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains.

Published in:

PLoS Pathogens, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.ppat.1005584

By:

Wang, Chong;
Long, Wenying;
Peng, Chao;
Hu, Lin;
Zhang, Qiong;
Wu, Ailing;
Zhang, Xiaoqing;
Duan, Xiaotao;
Wong, Catherine C. L.;
Tanaka, Yuetsu;
Xia, Zongping

Publication type:

Article

Increased Expression of Estrogen Receptor α-36 by Breast Cancer Oncogene IKKε Promotes Growth of ER-Negative Breast Cancer Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2013, v. 31, n. 6, p. 833, doi. 10.1159/000350101

By:

Li, Qihong;
Sun, Haiyan;
Zou, Jingcai;
Ge, Cheng;
Yu, Kaitao;
Cao, Yuan;
Hong, Quan

Publication type:

Article

Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03631

By:

Tilstra, Jeremy S.;
Gaddy, Daniel F.;
Jing Zhao;
Davé, Shaival H.;
Niedernhofer, Laura J.;
Plevy, Scott E.;
Robbins, Paul D.

Publication type:

Article

Integrity of IKK/NF‐κB Shields Thymic Stroma That Suppresses Susceptibility to Autoimmunity, Fungal Infection, and Carcinogenesis.

Published in:

BioEssays, 2018, v. 40, n. 4, p. 1, doi. 10.1002/bies.201700131

By:

Zhu, Feng;
Hu, Yinling

Publication type:

Article

Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia.

Published in:

PLoS Genetics, 2016, v. 12, n. 12, p. 1, doi. 10.1371/journal.pgen.1006486

By:

Naftelberg, Shiran;
Abramovitch, Ziv;
Gluska, Shani;
Yannai, Sivan;
Joshi, Yuvraj;
Donyo, Maya;
Ben-Yaakov, Keren;
Gradus, Tal;
Zonszain, Jonathan;
Farhy, Chen;
Ashery-Padan, Ruth;
Perlson, Eran;
Ast, Gil

Publication type:

Article

IKK-related genetic diseases: probing NF-κB functions in humans and other matters.

Published in:

Cellular & Molecular Life Sciences, 2015, v. 72, n. 7, p. 1275, doi. 10.1007/s00018-014-1793-y

By:

Senegas, Anna;
Gautheron, Jérémie;
Maurin, Alice;
Courtois, Gilles

Publication type:

Article

Erratum to: IKK-related genetic diseases: probing NF-κB functions in humans and other matters.

Published in:

2015

By:

Senegas, Anna;
Gautheron, Jérémie;
Gentil Dit Maurin, Alice;
Courtois, Gilles

Publication type:

Erratum

Correction.

Published in:: 2013
Publication type:: Correction Notice

Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/849541

By:

Salminen, Antero;
Hyttinen, Juha M. T.;
Kauppinen, Anu;
Kaarniranta, Kai

Publication type:

Article

Hypoxia activates IKK-NF-κB and the immune response in Drosophila melanogaster.

Published in:

Bioscience Reports, 2014, v. 34, n. 4, p. 429, doi. 10.1042/BSR20140095

By:

BANDARRA, Daniel;
BIDDLESTONE, John;
MUDIE, Sharon;
MULLER, H. Arno;
ROCHA, Sonia

Publication type:

Article

A feedforward loop of NLRC5 (de)ubiquitination keeps IKK-NF-κB in check.

Published in:

Journal of Cell Biology, 2015, v. 211, n. 5, p. 941, doi. 10.1083/jcb.201511039

By:

Yinling Hu

Publication type:

Article

Polymorphisms of IKBKE gene are associated with major depressive disorder and panic disorder.

Published in:

Brain & Behavior, 2015, v. 5, n. 4, p. n/a, doi. 10.1002/brb3.314

By:

Traks, Tanel;
Koido, Kati;
Balõtšev, Roman;
Eller, Triin;
Kõks, Sulev;
Maron, Eduard;
Tõru, Innar;
Shlik, Jakov;
Vasar, Eero;
Vasar, Veiko

Publication type:

Article

IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites.

Published in:

Mucosal Immunology (1933-0219), 2014, v. 7, n. 2, p. 257, doi. 10.1038/mi.2013.43

By:

Bonnegarde-Bernard, A;
Jee, J;
Fial, M J;
Aeffner, F;
Cormet-Boyaka, E;
Davis, I C;
Lin, M;
Tomé, D;
Karin, M;
Sun, Y;
Boyaka, P N

Publication type:

Article

Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-κB Inhibitor A20 and Constitutive NF-κB Signaling.

Published in:

PLoS Pathogens, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.ppat.1004721

By:

Pujari, Rajeshree;
Hunte, Richard;
Thomas, Remy;
van der Weyden, Louise;
Rauch, Dan;
Ratner, Lee;
Nyborg, Jennifer K.;
Ramos, Juan Carlos;
Takai, Yoshimi;
Shembade, Noula

Publication type:

Article

Role of cAMP and IKK-2-Dependent Signaling in the Realization of Growth Potential of Mesenchymal Progenitor Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2013, v. 156, n. 2, p. 228, doi. 10.1007/s10517-013-2317-8

By:

Zyuz'kov, G.;
Zhdanov, V.;
Danilets, M.;
Udut, E.;
Miroshnichenko, L.;
Ligacheva, A.;
Simanina, E.;
Trofimova, E.;
Minakova, M.;
Chaikovskii, A.;
Dygai, A.

Publication type:

Article

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.

Published in:

Oncogene, 2014, v. 33, n. 9, p. 1135, doi. 10.1038/onc.2013.49

By:

Nottingham, L K;
Yan, C H;
Yang, X;
Si, H;
Coupar, J;
Bian, Y;
Cheng, T-F;
Allen, C;
Arun, P;
Gius, D;
Dang, L;
Van Waes, C;
Chen, Z

Publication type:

Article

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.

Published in:

Oncogene, 2013, v. 32, n. 41, p. 4892, doi. 10.1038/onc.2012.517

By:

Jin, S;
Mutvei, A P;
Chivukula, I V;
Andersson, E R;
Ramsköld, D;
Sandberg, R;
Lee, K L;
Kronqvist, P;
Mamaeva, V;
Östling, P;
Mpindi, J-P;
Kallioniemi, O;
Screpanti, I;
Poellinger, L;
Sahlgren, C;
Lendahl, U

Publication type:

Article

Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130441

By:

Zhang, Jing;
Li, Li;
Jr.Baldwin, Albert S.;
Friedman, Alan D.;
Paz-Priel, Ido

Publication type:

Article

Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125709

By:

Patil, Kalpesh R.;
Mohapatra, Purusottam;
Patel, Harun M.;
Goyal, Sameer N.;
Ojha, Shreesh;
Kundu, Chanakya N.;
Patil, Chandragouda R.

Publication type:

Article

IKAP Deficiency in an FD Mouse Model and in Oligodendrocyte Precursor Cells Results in Downregulation of Genes Involved in Oligodendrocyte Differentiation and Myelin Formation.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094612

By:

Cheishvili, David;
Dietrich, Paula;
Maayan, Channa;
Even, Aviel;
Weil, Miguel;
Dragatsis, Ioannis;
Razin, Aharon

Publication type:

Article

IKKε Knockout Prevents High Fat Diet Induced Arterial Atherosclerosis and NF-κB Signaling in Mice

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064930

By:

Cao, Changchun;
Zhu, Yifan;
Chen, Wen;
Li, Liangpeng;
Qi, Yongchao;
Wang, Xiaodi;
Zhao, Ye;
Wan, Xin;
Chen, Xin

Publication type:

Article

The Influenza Virus Protein PB1-F2 Interacts with IKKβ and Modulates NF-κB Signalling

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063852

By:

Reis, Ana Luísa;
McCauley, John W.

Publication type:

Article

Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia.

Published in:

Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00076

By:

Liu, Lu;
An, Dandan;
Xu, Junying;
Shao, Bin;
Li, Xing;
Shi, Jing

Publication type:

Article

Immunodeficiency Associated with a Nonsense Mutation of IKBKB.

Published in:

Journal of Clinical Immunology, 2014, v. 34, n. 8, p. 916, doi. 10.1007/s10875-014-0097-1

By:

Nielsen, Christian;
Jakobsen, Marianne;
Larsen, Martin;
Müller, Amanda;
Hansen, Soren;
Lillevang, Søren;
Fisker, Niels;
Barington, Torben

Publication type:

Article

S100A4 suppresses cancer stem cell proliferation via interaction with the IKK/NF-κB signaling pathway.

Published in:

2018

By:

Zhu, Yongtong;
Zhou, Yao;
Zhou, Xuan;
Guo, Yangchun;
Huang, Daxiong;
Zhang, Jialin;
Wang, Chunyan;
Cai, Longmei

Publication type:

journal article

The Ah Receptor Recruits IKKα to Its Target Binding Motifs to Phosphorylate Serine-10 in Histone H3 Required for Transcriptional Activation.

Published in:

Toxicological Sciences, 2014, v. 139, n. 1, p. 121, doi. 10.1093/toxsci/kfu027

By:

Kurita, Hisaka;
Schnekenburger, Michael;
Ovesen, Jerald L.;
Xia, Ying;
Puga, Alvaro

Publication type:

Article

Tamoxifen reduces infiltration of inflammatory cells, apoptosis and inhibits IKK/NF-kB pathway after spinal cord injury in rats.

Published in:

Neurological Sciences, 2014, v. 35, n. 11, p. 1763, doi. 10.1007/s10072-014-1828-z

By:

Wei, Hong-yu;
Ma, Xiao

Publication type:

Article

IKKε aggravates inflammatory response via phosphorylation of ERK in rheumatoid arthritis.

Published in:

European Review for Medical & Pharmacological Sciences, 2018, v. 22, n. 7, p. 2126

By:

ZHOU, L.-F.;
ZENG, W.;
SUN, L.-C.;
WANG, Y.;
JIANG, F.;
LI, X.;
ZHENG, Y.;
WU, G.-M.

Publication type:

Article

Sumoylation of IkB attenuates NF-kB-induced nitrosative stress at rostral ventrolateral medulla and cardiovascular depression in experimental brain death.

Published in:

Journal of Biomedical Science, 2016, v. 23, p. 1, doi. 10.1186/s12929-016-0283-y

By:

Ching-Yi Tsai;
Li, Faith C. H.;
Wu, Carol H. Y.;
Chang, Alice Y. W.;
Chan, Samuel H. H.

Publication type:

Article

IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0116-1

By:

Min Jung Lee;
So Jin Bing;
Jonghee Choi;
Minhee Jang;
Gihyun Lee;
Hyunkyoung Lee;
Byung Soo Chang;
Youngheun Jee;
Sung Joong Lee;
Ik-Hyun Cho

Publication type:

Article

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.

Published in:

Nature Immunology, 2014, v. 15, n. 4, p. 323, doi. 10.1038/ni.2833

By:

Everts, Bart;
Amiel, Eyal;
Huang, Stanley Ching-Cheng;
Smith, Amber M;
Chang, Chih-Hao;
Lam, Wing Y;
Redmann, Veronika;
Freitas, Tori C;
Blagih, Julianna;
van der Windt, Gerritje J W;
Artyomov, Maxim N;
Jones, Russell G;
Pearce, Erika L;
Pearce, Edward J

Publication type:

Article

A novel IKKα inhibitor, noraristeromycin, blocks the chronic inflammation associated with collagen-induced arthritis in mice.

Published in:

Modern Rheumatology, 2014, v. 24, n. 5, p. 775, doi. 10.3109/14397595.2013.879416

By:

Ito, Masumi;
Hamano, Takaichi;
Komatsu, Takao;
Asamitsu, Kaori;
Yamakawa, Tomio;
Okamoto, Takashi

Publication type:

Article

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 2231, doi. 10.1172/JCI64498

By:

Ning Li;
Xuefeng Wu;
Holzer, Ryan G.;
Jun-Hee Lee;
Todoric, Jelena;
Eek-Joong Park;
Hisanobu Ogata;
Gukovskaya, Anna S.;
Gukovsky, Ilya;
Pizzo, Donald P.;
VandenBerg, Scott;
Tarin, David;
Atay, Çiğdem;
Arkan, Melek C.;
Deerinck, Thomas J.;
Moscat, Jorge;
Diaz-Meco, Maria;
Dawson, David;
Erkan, Mert;
Kleeff, Jörg

Publication type:

Article

CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 2244, doi. 10.1172/JCI66466

By:

Starokadomskyy, Petro;
Gluck, Nathan;
Haiying Li;
Baozhi Chen;
Wallis, Mathew;
Maine, Gabriel N.;
Xicheng Mao;
Zaidi, Iram W.;
Hein, Marco Y.;
McDonald, Fiona J.;
Lenzner, Steffen;
Zecha, Agnes;
Ropers, Hans-Hilger;
Kuss, Andreas W.;
McGaughran, Julie;
Gecz, Jozef;
Burstein, Ezra

Publication type:

Article