Works about HYPOXIA-inducible factors

Results: 1984

The Distinct Role of HIF-1α and HIF-2α in Hypoxia and Angiogenesis.

Published in:

Cells (2073-4409), 2025, v. 14, n. 9, p. 673, doi. 10.3390/cells14090673

By:

Bakleh, Mouayad Zuheir;
Al Haj Zen, Ayman

Publication type:

Article

In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1583587

By:

Ye, Yi;
Wang, Yanjun;
Xu, Qiying;
Liu, Juanli;
Yang, Ziqi;
Wuren, Tana;
Ge, Ri-Li

Publication type:

Article

Panthotenic Acid Derrivate Dexpanthenol Mitigates the Effects of Lung Ischemia-Reperfusion Induced Cardiac Damage by its Anti-Inflammatory Action.

Published in:

Medical Journal of Suleyman Demirel University, 2025, v. 32, n. 1, p. 73, doi. 10.17343/sdutfd.1530958

By:

SAVRAN, Mehtap;
ARLIOGLU, Melih;
OZMEN, Ozlem

Publication type:

Article

The hypoxic microenvironment of Candida albicans biofilms shapes neutrophil responses.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1547559

By:

Juszczak, Magdalena;
Brankiewicz, Aleksandra;
Zawrotniak, Marcin;
Rapala-Kozik, Maria

Publication type:

Article

α-tocopherol supplementation prevents lead acetate and hypoxia-induced hepatic dysfunction.

Published in:

Indian Journal of Pharmacology, 2015, v. 47, n. 3, p. 285, doi. 10.4103/0253-7613.157126

By:

Das, Kusal K.;
Jargar, Jameel G.;
Saha, Sikha;
Yendigeri, Saeed M.;
Singh, Shashi Bala

Publication type:

Article

Linoleate-Containing Acylglucosylceramide, Acylceramide, and Events Associated with Formation of the Epidermal Permeability Barrier.

Published in:

Skin Pharmacology & Physiology, 2023, v. 36, n. 5, p. 225, doi. 10.1159/000535049

By:

Wertz, Philip W.

Publication type:

Article

HIF-1α Stimulators Function Equally to Leading Hair Loss Agents in Enhancing Dermal Papilla Growth.

Published in:

Skin Pharmacology & Physiology, 2020, v. 33, n. 6, p. 309, doi. 10.1159/000512123

By:

Bukowiecki, Julia;
Pförringer, Dominik;
Thor, Dominik;
Duscher, Dominik;
Brett, Elizabeth

Publication type:

Article

Correction: Hypoxia-Inducible Factor Directs POMC Gene to Mediate Hypothalamic Glucose Sensing and Energy Balance Regulation.

Published in:

2016

By:

Zhang, Hai;
Zhang, Guo;
Gonzalez, Frank J.;
Park, Sung-min;
Cai, Dongsheng

Publication type:

Correction Notice

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.

Published in:

PLoS Biology, 2016, v. 14, n. 1, p. 1, doi. 10.1371/journal.pbio.1002347

By:

Scholz, Carsten C.;
Rodriguez, Javier;
Pickel, Christina;
Burr, Stephen;
Fabrizio, Jacqueline-alba;
Nolan, Karen A.;
Spielmann, Patrick;
Cavadas, Miguel A. S.;
Crifo, Bianca;
Halligan, Doug N.;
Nathan, James A.;
Peet, Daniel J.;
Wenger, Roland H.;
Von Kriegsheim, Alex;
Cummins, Eoin P.;
Taylor, Cormac T.

Publication type:

Article

Hypoxia-Inducible Factor-2α Is an Essential Catabolic Regulator of Inflammatory Rheumatoid Arthritis.

Published in:

PLoS Biology, 2014, v. 12, n. 6, p. 1, doi. 10.1371/journal.pbio.1001881

By:

Ryu, Je-Hwang;
Chae, Chang-Suk;
Kwak, Ji-Sun;
Oh, Hwanhee;
Shin, Youngnim;
Huh, Yun Hyun;
Lee, Choong-Gu;
Park, Yong-Wook;
Chun, Churl-Hong;
Kim, Young-Myeong;
Im, Sin-Hyeog;
Chun, Jang-Soo

Publication type:

Article

Hypoxia-Inducible Factor Directs POMC Gene to Mediate Hypothalamic Glucose Sensing and Energy Balance Regulation.

Published in:

PLoS Biology, 2011, v. 9, n. 7, p. 1, doi. 10.1371/journal.pbio.1001112

By:

Zhang, Hai;
Zhang, Guo;
Gonzalez, Frank J.;
Park, Sung-min;
Cai1, Dongsheng

Publication type:

Article

CircAKT3 inhibits glycolysis balance in lung cancer cells by regulating miR-516b-5p/STAT3 to inhibit cisplatin sensitivity.

Published in:

Biotechnology Letters, 2020, v. 42, n. 7, p. 1123, doi. 10.1007/s10529-020-02846-9

By:

Xu, Yangling;
Jiang, Tiantian;
Wu, Changgang;
Zhang, Yongqing

Publication type:

Article

MiR-429 improved the hypoxia tolerance of human amniotic cells by targeting HIF-1α.

Published in:

Biotechnology Letters, 2018, v. 40, n. 11/12, p. 1477, doi. 10.1007/s10529-018-2604-6

By:

Ge, Lihao;
Wang, Yuyan;
Cao, Yang;
Li, Gang;
Sun, Rui;
Teng, Peng;
Wang, Yansong;
Bi, Yunlong;
Guo, Zhanpeng;
Yuan, Yajiang;
Yu, Deshui

Publication type:

Article

Initial experience of hypoxia-inducible factor prolyl hydroxylase inhibitors in patients with heart failure and renal anemia.

Published in:

Heart & Vessels, 2023, v. 38, n. 2, p. 284, doi. 10.1007/s00380-022-02181-1

By:

Nakamura, Makiko;
Imamura, Teruhiko;
Sobajima, Mitsuo;
Kinugawa, Koichiro

Publication type:

Article

Mesenchymal stem cells inhibit hypoxia-induced inflammatory and fibrotic pathways in bladder smooth muscle cells.

Published in:

World Journal of Urology, 2018, v. 36, n. 7, p. 1157, doi. 10.1007/s00345-018-2247-1

By:

Wiafe, Bridget;
Adesida, Adetola;
Churchill, Thomas;
Metcalfe, Peter

Publication type:

Article

Does hypoxia-inducible factor 1α play a role in regulating cutaneous oxygen flux in larval zebrafish (Danio rerio)?

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2021, v. 191, n. 4, p. 645, doi. 10.1007/s00360-021-01361-1

By:

Parker, Julian J.;
Perry, Steve F.

Publication type:

Article

Identification of HIF-1 signaling pathway in Pelteobagrus vachelli using RNA-Seq: effects of acute hypoxia and reoxygenation on oxygen sensors, respiratory metabolism, and hematology indices.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2017, v. 187, n. 7, p. 931, doi. 10.1007/s00360-017-1083-8

By:

Zhang, Guosong;
Zhao, Cheng;
Wang, Qintao;
Gu, Yichun;
Li, Zecheng;
Tao, Panfeng;
Chen, Jiawei;
Yin, Shaowu

Publication type:

Article

Pretreatment Apparent Diffusion Coefficient Cannot Predict Histopathological Features and Response to Neoadjuvant Radiochemotherapy in Rectal Cancer: A Meta-Analysis.

Published in:

Digestive Diseases, 2022, v. 40, n. 1, p. 33, doi. 10.1159/000515631

By:

Surov, Alexey;
Pech, Maciej;
Powerski, Maciej;
Woidacki, Katja;
Wienke, Andreas

Publication type:

Article

Oxyquinoline-Dependent Changes in Claudin-Encoding Genes Contribute to Impairment of the Barrier Function of the Trophoblast Monolayer.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 6, p. 369, doi. 10.1007/s10517-019-04352-z

By:

Knyazev, E. N.;
Petrov, V. A.;
Gazizov, I. N.;
Gerasimenko, T. N.;
Tsypina, I. M.;
Tonevitsky, A. G.;
Sukhikh, G. T.

Publication type:

Article

Oxyquinoline-Dependent Changes in Claudin-Encoding Genes Contribute to Impairment of the Barrier Function of the Trophoblast Monolayer.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 3, p. 369, doi. 10.1007/s10517-019-04352-z

By:

Knyazev, E. N.;
Petrov, V. A.;
Gazizov, I. N.;
Gerasimenko, T. N.;
Tsypina, I. M.;
Tonevitsky, A. G.;
Sukhikh, G. T.

Publication type:

Article

Involvement of Autonomic Nervous System in Antiarrhythmic Effect of Intermittent Hypobaric Hypoxia.

Published in:

Bulletin of Experimental Biology & Medicine, 2017, v. 163, n. 3, p. 299, doi. 10.1007/s10517-017-3789-8

By:

Lasukova, T.;
Naryzhnaya, N.;
Mukhamedzyanov, A.;
Maslov, L.

Publication type:

Article

Hypoxic preconditioning facilitates acclimatization to hypobaric hypoxia in rat heart.

Published in:

Journal of Pharmacy & Pharmacology, 2010, v. 62, n. 12, p. 1729, doi. 10.1111/j.2042-7158.2010.01163.x

By:

Singh, Mrinalini;
Shukla, Dhananjay;
Thomas, Pauline;
Saxena, Saurabh;
Bansal, Anju

Publication type:

Article

Increasing the Anaerobic Capacity Resulting from the Improvement of Buffering and Hypoxia Indicators in Healthy Men.

Published in:

Jentashapir Journal of Cellular & Molecular Biology, 2024, v. 15, n. 4, p. 1, doi. 10.5812/jjcmb-156641

By:

Nasiri, Samira;
Banitalebi, Ebrahim;
Faramarzi, Mohammad

Publication type:

Article

Associations between HIFs and tumor immune checkpoints: mechanism and therapy.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-023-00836-7

By:

Liu, Jiayu;
Jiang, Ying;
Chen, Lingyan;
Qian, Zhiwen;
Zhang, Yan

Publication type:

Article

Tumor Hypoxia and Radioresistance.

Published in:

Radiology News Journal / Radiološki Vjesnik, 2024, v. 48, n. 2, p. 52, doi. 10.55378/rv.48.2.6

By:

Morović, Sara

Publication type:

Article

Ritonavir inhibits HIF-1α-mediated VEGF expression in retinal pigment epithelial cells in vitro.

Published in:

Eye (0950-222X), 2014, v. 28, n. 1, p. 93, doi. 10.1038/eye.2013.240

By:

Vadlapatla, R K;
Vadlapudi, A D;
Pal, D;
Mukherji, M;
Mitra, A K

Publication type:

Article

Association study of a single nucleotide polymorphism in the hypoxia response element of the macrophage migration inhibitory factor gene promoter with suicide completers in the Japanese population.

Published in:

Neuropsychopharmacology Reports, 2024, v. 44, n. 1, p. 262, doi. 10.1002/npr2.12410

By:

Shirai, Toshiyuki;
Okazaki, Satoshi;
Tanifuji, Takaki;
Otsuka, Ikuo;
Miyachi, Masao;
Okada, Shohei;
Shindo, Ryota;
Horai, Tadasu;
Mouri, Kentaro;
Takahashi, Motonori;
Kondo, Takeshi;
Ueno, Yasuhiro;
Hishimoto, Akitoyo

Publication type:

Article

Preparation of EGCG decorated, injectable extracellular vesicles for cartilage repair in rat arthritis.

Published in:

Regenerative Biomaterials, 2021, v. 8, n. 6, p. 1, doi. 10.1093/rb/rbab067

By:

Song, Changwei;
Xu, Shibo;
Chang, Linna;
Zhao, Xingjun;
Mei, Xifan;
Ren, Xiuli;
Chen, Zhenhua

Publication type:

Article

Hypoxia-inducible factor prolyl hydroxylase inhibitor-induced thrombosis leading to transcatheter aortic valve dysfunction: a case report.

Published in:

2025

By:

Ikuta, Akihiro;
Matsushita, Syunsuke;
Kadota, Kazushige;
Komiya, Tatsuhiko;
Fuku, Yasushi

Publication type:

Case Study

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer.

Published in:

Non-Coding RNA, 2020, v. 6, n. 3, p. 1, doi. 10.3390/ncrna6030027

By:

Barth, Dominik A.;
Prinz, Felix;
Teppan, Julia;
Jonas, Katharina;
Klec, Christiane;
Pichler, Martin

Publication type:

Article

Exogenous Ang-(1-7) inhibits autophagy via HIF-1α/THBS1/BECN1 axis to alleviate chronic intermittent hypoxia-enhanced airway remodelling of asthma.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01662-0

By:

Zhou, Jian Ping;
Wang, Yi;
Li, Shi Qi;
Zhang, Jia Qi;
Lin, Ying Ni;
Sun, Xian Wen;
Zhou, Li Na;
Zhang, Liu;
Lu, Fang Ying;
Ding, Yong Jie;
Li, Qing Yun

Publication type:

Article

Divergence time estimates for the hypoxia‐inducible factor‐1 alpha (HIF1α) reveal an ancient emergence of animals in low‐oxygen environments.

Published in:

Geobiology, 2024, v. 22, n. 1, p. 1, doi. 10.1111/gbi.12577

By:

Belato, Flavia A.;
Mello, Beatriz;
Coates, Christopher J.;
Halanych, Kenneth M.;
Brown, Federico D.;
Morandini, André C.;
de Moraes Leme, Juliana;
Trindade, Ricardo I. F.;
Costa‐Paiva, Elisa Maria

Publication type:

Article

Role of HIF‐1α in pathogenic mechanisms of keloids.

Published in:

Journal of Cosmetic Dermatology, 2023, v. 22, n. 5, p. 1436, doi. 10.1111/jocd.15601

By:

Qiu, Zi‐kai;
Zhang, Ming‐zi;
Zhang, Wen‐chao;
Li, Zhi‐jin;
Si, Lou‐bin;
Long, Xiao;
Yu, Nan‐ze;
Wang, Xiao‐jun

Publication type:

Article

Anti-fibrotic effect of tocotrienols for bladder dysfunction due to partial bladder outlet obstruction.

Published in:

Investigative & Clinical Urology, 2023, v. 64, n. 2, p. 189, doi. 10.4111/icu.20220328

By:

Nao Iguchi;
Dönmez, M. İrfan;
Malykhina, Anna P.;
Wilcox, Duncan T.

Publication type:

Article

The therapeutic prospect of zinc oxide nanoparticles in experimentally induced diabetic nephropathy.

Published in:

Tissue Barriers, 2023, v. 11, n. 1, p. 1, doi. 10.1080/21688370.2022.2069966

By:

Abd El-Baset, Samia A.;
Mazen, Nehad F.;
Abdul-Maksoud, Rehab S.;
Kattaia, Asmaa A. A.

Publication type:

Article

JmjC histone demethylases act as chromatin oxygen sensors.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 4, p. N.PAG, doi. 10.1080/23723556.2019.1608501

By:

Batie, Michael;
Rocha, Sonia

Publication type:

Article

Ficus carica Puree Exerts a Higher Antioxidative Profile in Hypoxic Lungs after Intermittently Inducing Hypoxia in Sprague–Dawley Rats.

Published in:

Journal of Medical Sciences (1011-4564), 2024, v. 44, n. 6, p. 262, doi. 10.4103/jmedsci.jmedsci_39_24

By:

Fitri, Ayu Tiara;
Meliala, Andreanyta;
Widyawati, Dwi;
Narwidina, Paramita;
Siswanto, Siswanto;
Sumarno, Yogi Tri

Publication type:

Article

Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.89173

By:

Warnhoff, Kurt;
Bhattacharya, Sushila;
Snoozy, Jennifer;
Breen, Peter C.;
Ruvkun, Gary

Publication type:

Article

Evaluations of the combined use of blood- and tissue-based protein biomarkers for pancreatic cancer.

Published in:

Clinical Hemorheology & Microcirculation, 2024, v. 86, n. 3, p. 383, doi. 10.3233/CH-231987

By:

Wiewiora, Maciej;
Jopek, Janusz;
Świętochowska, Elżbieta;
Grynkiewicz, Michael;
Piecuch, Jerzy

Publication type:

Article

Methylation of HIF3A promoter CpG islands contributes to insulin resistance in gestational diabetes mellitus.

Published in:

Molecular Genetics & Genomic Medicine, 2019, v. 7, n. 4, p. N.PAG, doi. 10.1002/mgg3.583

By:

Zhang, Yinghong;
Chen, Yangyang;
Qu, Hongmei;
Wang, Yuanli

Publication type:

Article

VHH212 nanobody targeting the hypoxia-inducible factor 1α suppresses angiogenesis and potentiates gemcitabine therapy in pancreatic cancer in vivo.

Published in:

Cancer Biology & Medicine, 2021, v. 18, n. 3, p. 772, doi. 10.20892/j.issn.2095-3941.2020.0568

By:

Guangbo Kang;
Min Hu;
He Ren;
Jiewen Wang;
Xin Cheng;
Ruowei Li;
Bo Yuan;
Yasmine Balan;
Zixuan Bai;
He Huang

Publication type:

Article

Three-dimensional collagen-based scaffold model to study the microenvironment and drug-resistance mechanisms oforopharyngeal squamous cell carcinomas.

Published in:

Cancer Biology & Medicine, 2021, v. 18, n. 2, p. 502, doi. 10.20892/j.issn.2095-3941.2020.0482

By:

Miserocchi, Giacomo;
Cocchi, Claudia;
De Vita, Alessandro;
Liverani, Chiara;
Spadazzi, Chiara;
Calpona, Sebastiano;
Menna, Giandomenico Di;
Bassi, Massimo;
Meccariello, Giuseppe;
De Luca, Giovanni;
Campobassi, Angelo;
Tumedei, Maria Maddalena;
Bongiovanni, Alberto;
Fausti, Valentina;
Cotelli, Franco;
ToniIbrahim;
Mercatali, Laura

Publication type:

Article

Increased formation of neutrophil extracellular traps induced by autophagy and identification of autophagy‐related biomarkers in systemic lupus erythematosus.

Published in:

Experimental Dermatology, 2024, v. 33, n. 1, p. 1, doi. 10.1111/exd.14881

By:

Li, Mingfang;
Weng, Luobei;
Yu, Datang;
Yang, Guofei;
Hao, Jin

Publication type:

Article

Expression of hypoxia-inducible genes is suppressed in altered gravity due to impaired nuclear HIF1α accumulation.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41686-1

By:

Aboouf, Mostafa A.;
Thiel, Cora S.;
Borisov, Sergey M.;
Tauber, Svantje;
Bönzli, Eva;
Schetle, Nelli;
Ullrich, Oliver;
Gassmann, Max;
Vogel, Johannes

Publication type:

Article

Expression of hypoxia-inducible genes is suppressed in altered gravity due to impaired nuclear HIF1α accumulation.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41686-1

By:

Aboouf, Mostafa A.;
Thiel, Cora S.;
Borisov, Sergey M.;
Tauber, Svantje;
Bönzli, Eva;
Schetle, Nelli;
Ullrich, Oliver;
Gassmann, Max;
Vogel, Johannes

Publication type:

Article

Simvastatin alleviates bone resorption in apical periodontitis possibly by inhibition of mitophagy‐related osteoblast apoptosis.

Published in:

International Endodontic Journal, 2019, v. 52, n. 5, p. 676, doi. 10.1111/iej.13055

By:

Yang, C.‐N.;
Kok, S.‐H.;
Wang, H.‐W.;
Chang, J. Z.‐C.;
Lai, E. H.‐H.;
Shun, C.‐T.;
Yang, H.;
Chen, M.‐H.;
Hong, C.‐Y.;
Lin, S.‐K.

Publication type:

Article

The roles of autophagy and hypoxia in human inflammatory periapical lesions.

Published in:

International Endodontic Journal, 2018, v. 51, p. e125, doi. 10.1111/iej.12782

By:

Huang, H. Y.;
Wang, W. C.;
Lin, P. Y.;
Huang, C. P.;
Chen, C. Y.;
Chen, Y. K.

Publication type:

Article

Sirtuin 6 attenuates periapical lesion propagation by modulating hypoxia‐induced chemokine (C‐C motif) ligand 2 production in osteoblasts.

Published in:

International Endodontic Journal, 2018, v. 51, p. e74, doi. 10.1111/iej.12742

By:

Lee, Y.‐L.;
Lin, S.‐K.;
Hou, K.‐L.;
Kok, S.‐H.;
Lai, E. H.‐H.;
Wang, H.‐W.;
Chang, J. Z.‐C.;
Yang, H.;
Hong, C.‐Y.

Publication type:

Article

Exploring the natural products chemical space through a molecular search to discover potential inhibitors that target the hypoxia-inducible factor (HIF) prolyl hydroxylase domain (PHD).

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1202128

By:

Sayaf, Abrar Mohammad;
Khalid, Saif Ullah;
Hameed, Jawad Ahmed;
Alshammari, Abdulrahman;
Khan, Abbas;
Mohammad, Anwar;
Alghamdi, Saeed;
Dong-Qing Wei;
KarKheng Yeoh

Publication type:

Article

Safety of HIF prolyl hydroxylase inhibitors for anemia in dialysis patients: a systematic review and network meta-analysis.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1163908

By:

Dinghua Chen;
Yue Niu;
Fei Liu;
Yue Yang;
Xue Wang;
Ping Li;
Xiangmei Chen

Publication type:

Article