Works about HYPOXIA-inducible factor 1

Results: 1685

Wuhan strain of SARS-CoV-2 triggers activation of immune evasion machinery similar to the one operated by cancer cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1599352

By:

Abooali, Maryam;
Yasinska, Inna M.;
Thapa, Gauri;
Lei, Xi;
da Costa, Kelly A. S.;
Schlichtner, Stephanie;
Berger, Steffen M.;
Fasler-Kan, Elizaveta;
Temperton, Nigel J.;
Vuono, Romina;
Sumbayev, Vadim V.

Publication type:

Article

Immunohistochemical expression of hypoxia inducible factor-1 alpha (Hif -1a) in patients of head and neck squamous cell carcinoma.

Published in:

Journal of University Medical & Dental College, 2025, v. 16, n. 2, p. 1046, doi. 10.37723/jumdc.v16i2.1073

By:

Kazmi, Syeda Sadaf;
Anjum, Rabia;
Ali, Waqar;
Rahman, Aman ur;
Qazi, Zia us Salam;
Chaudhry, Saima

Publication type:

Article

HIF‐1α‐Induced GPR171 Expression Mediates CCL2 Secretion by Mast Cells to Promote Gastric Inflammation During Helicobacter pylori Infection.

Published in:

Helicobacter, 2025, v. 30, n. 3, p. 1, doi. 10.1111/hel.70042

By:

Yuan, Hanmei;
Li, Yuetong;
Wu, Hui;
Zhang, Jin;
Xia, Tingting;
Li, Bin;
Wu, Chao

Publication type:

Article

Aflatoxin B1 and Eimeria ovinoidalis impairs meat quality of sheep by regulating the HIF-1ɑ/HK2/glycolysis axis.

Published in:

NPJ Science of Food, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41538-025-00490-z

By:

He, Yan-feng;
Tong, Xi-shuai;
Yue, Ke;
Xu, Bo-wen;
Ding, Wen-li;
Lu, Ya-nan;
Yue, Tao-jing;
Chen, Pan;
Liu, Kai-li;
Shaukat, Aftab;
Li, Sen-yang;
Jian, Fu-chun;
Huang, Shu-cheng

Publication type:

Article

HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001665

By:

Eckle, Tobias;
Brodsky, Kelley;
Bonney, Megan;
Packard, Thomas;
Han, Jun;
Borchers, Christoph H.;
Mariani, Thomas J.;
Kominsky, Douglas J.;
Mittelbronn, Michel;
Eltzschig, Holger K.

Publication type:

Article

Inhibition of HIF2α Is Sufficient to Suppress pVHL-Defective Tumor Growth.

Published in:

PLoS Biology, 2003, v. 1, n. 12, p. 1, doi. 10.1371/journal.pbio.0000083

By:

Kondo, Keiichi;
Kim, William Y;
Lechpammer, Mirna;
Kaelin Jr, William G

Publication type:

Article

micro RNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis.

Published in:

Liver International, 2015, v. 35, n. 2, p. 532, doi. 10.1111/liv.12633

By:

Csak, Timea;
Bala, Shashi;
Lippai, Dora;
Satishchandran, Abishek;
Catalano, Donna;
Kodys, Karen;
Szabo, Gyongyi

Publication type:

Article

Hypoxia inducible factor-1 is involved in growth factor, glucocorticoid and hypoxia mediated regulation of vascular endothelial growth factor-A in human meningiomas.

Published in:

Journal of Neuro-Oncology, 2014, v. 119, n. 2, p. 263, doi. 10.1007/s11060-014-1503-5

By:

Wu, Y.;
Lucia, K.;
Lange, M.;
Kuhlen, D.;
Stalla, G.;
Renner, U.

Publication type:

Article

PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 1, p. 89, doi. 10.1007/s11060-013-1283-3

By:

Muh, Carrie;
Joshi, Shweta;
Singh, Alok;
Kesari, Santosh;
Durden, Donald;
Makale, Milan

Publication type:

Article

Evaluation of mast cells and hypoxia inducible factor-1 expression in meningiomas of various grades in correlation with peritumoral brain edema.

Published in:

Journal of Neuro-Oncology, 2013, v. 115, n. 1, p. 119, doi. 10.1007/s11060-013-1208-1

By:

Reszec, Joanna;
Hermanowicz, Adam;
Rutkowski, Robert;
Bernaczyk, Piotr;
Mariak, Zenon;
Chyczewski, Lech

Publication type:

Article

Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 3, p. 365, doi. 10.1007/s11060-013-1081-y

By:

Zhou, Xiuping;
Liu, Zhi;
Shi, Qiong;
Jiao, Jiantong;
Bian, Wenbin;
Song, Xu;
Mo, Jianbing;
sang, Ben;
Xu, Yinfu;
Qian, Jinming;
Chao, Yuewen;
Yu, Rutong

Publication type:

Article

MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells.

Published in:

Journal of Neuro-Oncology, 2013, v. 111, n. 3, p. 273, doi. 10.1007/s11060-012-1027-9

By:

Tanaka, Hirotomo;
Sasayama, Takashi;
Tanaka, Kazuhiro;
Nakamizo, Satoshi;
Nishihara, Masamitsu;
Mizukawa, Katsu;
Kohta, Masaaki;
Koyama, Junji;
Miyake, Shigeru;
Taniguchi, Masaaki;
Hosoda, Kohkichi;
Kohmura, Eiji

Publication type:

Article

Identification of HIF- 1α promoter and expression regulation of HIF- 1α gene by LPS and hypoxia in zebrafish.

Published in:

Fish Physiology & Biochemistry, 2013, v. 39, n. 5, p. 1153, doi. 10.1007/s10695-013-9771-0

By:

Liu, Shasha;
Zhu, Kecheng;
Chen, Nan;
Wang, Weimin;
Wang, Huanling

Publication type:

Article

Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00336-w

By:

Cheng, Wun-Hao;
Chen, Chia-Ling;
Chen, Jing-Yun;
Lin, Chien-Huang;
Chen, Bing-Chang

Publication type:

Article

Induction of heme oxygenase‐1 antagonizes PM2.5‐induced pulmonary VEGFA expression through regulating HIF‐1α.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 12, p. 1, doi. 10.1002/jbt.23494

By:

Xu, Huan;
Wen, Qing;
Xu, Xiuduan;
Liu, Zhihui;
Liu, Shasha;
Wang, Hongli;
Zhang, Chongchong;
Wan, Delian;
Liu, Kun;
Du, Lina;
Yuan, Chao;
Song, Lun

Publication type:

Article

Pinoresinol diglucoside ameliorates H/R‐induced injury of cardiomyocytes by regulating miR‐142‐3p and HIF1AN.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 10, p. 1, doi. 10.1002/jbt.23175

By:

Wei, Yuan;
Xiao, Liang;
Yingying, Liu;
Haichen, Wang

Publication type:

Article

Propranolol inhibits the activity of PI3K, AKT, and HIF-1α in infantile hemangiomas.

Published in:

2018

By:

Lin, Zhenying;
Wang, Luanhong;
Huang, Guang;
Wang, Wenyan;
Lin, Han

Publication type:

journal article

Effects of intermittent hypoxia training on leukocyte pyruvate dehydrogenase kinase 1 (PDK-1) mRNA expression and blood insulin level in prediabetes patients.

Published in:

2019

By:

Serebrovska, Tetiana V.;
Portnychenko, Alla G.;
Portnichenko, Vladimir I.;
Xi, Lei;
Egorov, Egor;
Antoniuk-Shcheglova, Ivanna;
Naskalova, Svitlana;
Shatylo, Valeriy B.

Publication type:

journal article

Characterization of the hypoxia-inducible factor 1 alpha gene in the sperm whale, beluga whale, and Yangtze finless porpoise.

Published in:

Marine Biology, 2015, v. 162, n. 6, p. 1201, doi. 10.1007/s00227-015-2662-4

By:

Bi, Jianling;
Hu, Bo;
Zheng, Jinsong;
Wang, Jingzhen;
Xiao, Wuhan;
Wang, Ding

Publication type:

Article

Overexpression of MAFG-AS1 in ovarian cancer promotes glucose metabolism reprogramming and malignant biological behavior of ovarian cancer cells by regulating HIF-1α.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02429-y

By:

Jia, Liu;
Yu, Fei

Publication type:

Article

Hypoxia signaling in cancer: HIF-1α stimulated by COVID-19 can lead to cancer progression and chemo-resistance in oral squamous cell carcinoma (OSCC).

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02150-w

By:

Eghbalifard, Negar;
Nouri, Nikta;
Rouzbahani, Shiva;
Bakhshi, Maryam;
Ghasemi Kahrizsangi, Negin;
Golafshan, Faraz;
Abbasi, Fatemeh

Publication type:

Article

The molecular mechanism of gemcitabine in inhibiting the HIF-1α/VEGFB/FGF2/FGFR1 signaling pathway for ovarian cancer treatment.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-024-01723-5

By:

Wang, Liangliang;
Ma, Shanshan;
Su, Huiwen;
Nie, Dandan;
Wang, Lihua

Publication type:

Article

Alginate–Gelatin Hydrogel Scaffold Model for Hypoxia Induction in Glioblastoma Embedded Spheroids.

Published in:

Gels (2310-2861), 2025, v. 11, n. 4, p. 263, doi. 10.3390/gels11040263

By:

del Rocío Aguilera-Marquez, Janette;
Manzanares-Guzmán, Alejandro;
García-Uriostegui, Lorena;
Canales-Aguirre, Alejandro A.;
Camacho-Villegas, Tanya A.;
Lugo-Fabres, Pavel H.

Publication type:

Article

Hypoxic preconditioning accelerates the healing of ischemic intestinal injury by activating HIF-1α/PPARα pathway-mediated fatty acid oxidation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01937-0

By:

Li, Linxia;
Liu, Yanqi;
Zhi, Na;
Ji, Yaoxuan;
Xu, Jialing;
Mao, Guoyun;
Wang, Yazhou;
Ma, Jin;
Wang, Yunying

Publication type:

Article

Hypoxia in prostate cancer.

Published in:

Nowotwory, 2017, v. 67, n. 2, p. 132, doi. 10.5603/NJO.2017.0021

By:

Danielska, Justyna;
Łuniewska-Bury, Jolanta;
Kuncman, Łukasz;
Fijuth, Jacek

Publication type:

Article

Iron Chelators in the Management of Autoimmune-Induced Alopecia: A Focus on Hypoxia-Inducible Factor 1 Modulation and Hair Restoration.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 7, p. 2133, doi. 10.3390/jcm14072133

By:

Pagani, Andrea;
Thor, Dominik;
Panayi, Adriana C.;
Klein, Silvan M.;
Geis, Sebastian;
Knoedler, Leonard;
Knoedler, Samuel;
Perozzo, Filippo A. G.;
Sofo, Giuseppe;
Loucas, Rafael;
Prantl, Lukas;
Duscher, Dominik

Publication type:

Article

New Pharmacological Therapies in the Treatment of Epilepsy in the Pediatric Population.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 12, p. 3567, doi. 10.3390/jcm13123567

By:

Daniłowska, Karolina;
Picheta, Natalia;
Żyła, Dominika;
Piekarz, Julia;
Zych, Katarzyna;
Gil-Kulik, Paulina

Publication type:

Article

Celecoxib Suppresses NF-κB p65 (RelA) and TNFα Expression Signaling in Glioblastoma.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 20, p. 6683, doi. 10.3390/jcm12206683

By:

Ahsan, Hina;
Malik, Shaukat Iqbal;
Shah, Fawad Ali;
El-Serehy, Hamed A.;
Ullah, Amin;
Shah, Zafar Abbas

Publication type:

Article

Myocardial Expression of Macrophage Migration Inhibitory Factor in Patients with Heart Failure.

Published in:

Journal of Clinical Medicine, 2017, v. 6, n. 10, p. 95, doi. 10.3390/jcm6100095

By:

Pohl, Julia;
Hendgen-Cotta, Ulrike B.;
Stock, Pia;
Luedike, Peter;
Baba, Hideo Andreas;
Kamler, Markus;
Rassaf, Tienush

Publication type:

Article

Single Cell RNA Sequencing (Scrna-seq) in Studying the Early Embryonic Muscle Development.

Published in:

Journal of Animal Science, 2022, v. 100, p. 190, doi. 10.1093/jas/skac247.349

By:

Liang Zhao;
Min Du

Publication type:

Article

Influence of maternal nutrition on placental vascularity and mRNA expression of angiogenic factors (AFs) and their receptors (AFRs) in adolescent sheep.

Published in:

Journal of Animal Science, 2006, v. 84, p. 347

By:

Redmer, D. A.;
Aitken, R. P.;
Milne, J. S.;
Johnson, M. L.;
Rouse, D.;
Borowicz, P. P.;
Borowicz, M.;
Kraft, K. C.;
Reynolds, L. P.;
Luther, J. S.;
Wallace, J. M.

Publication type:

Article

Hypoxia-Inducible Factor and Oxidative Stress in Tendon Degeneration: A Molecular Perspective.

Published in:

Antioxidants, 2024, v. 13, n. 1, p. 86, doi. 10.3390/antiox13010086

By:

Shahid, Hamzah;
Morya, Vivek Kumar;
Oh, Ji-Ung;
Kim, Jae-Hyung;
Noh, Kyu-Cheol

Publication type:

Article

Taurine as Antioxidant in a Novel Cell- and Oxygen Carrier-Free Perfusate for Normothermic Machine Perfusion of Porcine Kidneys.

Published in:

Antioxidants, 2023, v. 12, n. 3, p. 768, doi. 10.3390/antiox12030768

By:

Zarnitz, Laura;
Doorschodt, Benedict M.;
Ernst, Lisa;
Hosseinnejad, Aisa;
Edgworth, Eileen;
Fechter, Tamara;
Theißen, Alexander;
Djudjaj, Sonja;
Boor, Peter;
Rossaint, Rolf;
Tolba, René H.;
Bleilevens, Christian

Publication type:

Article

Hypoxia Affects the Antioxidant Activity of Glutaredoxin 3 in Scylla paramamosain through Hypoxia Response Elements.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 76, doi. 10.3390/antiox12010076

By:

Jie, Yu-Kun;
Cheng, Chang-Hong;
Ma, Hong-Ling;
Liu, Guang-Xin;
Fan, Si-Gang;
Jiang, Jian-Jun;
Guo, Zhi-Xun

Publication type:

Article

HIF-3 -Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop.

Published in:

2022

By:

Gao, Qiaohui;
Ren, Zhenghua;
Jiao, Shengyuan;
Guo, Juan;
Miao, Xia;
Wang, Jin;
Liu, Junye

Publication type:

journal article

Combined Effects of 2-Methoxyestradiol (Hypoxia-Inducible Factor 1 Inhibitor) and Dasatinib (A Second-Generation Tyrosine Kinase Inhibitor) on Chronic Myelocytic Leukemia Cells.

Published in:

2022

By:

Zhang, Yuexian;
Chen, Heng;
Shen, Yunfeng;
Zhou, Xin

Publication type:

journal article

Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.89173

By:

Warnhoff, Kurt;
Bhattacharya, Sushila;
Snoozy, Jennifer;
Breen, Peter C.;
Ruvkun, Gary

Publication type:

Article

Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85597

By:

Ciampa, Erin J.;
Flahardy, Padraich;
Srinivasan, Harini;
Jacobs, Christopher;
Tsai, Linus;
Karumanchi, S. Ananth;
Parikh, Samir M.

Publication type:

Article

Searching for molecular hypoxia sensors among oxygen-dependent enzymes.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.87705

By:

Li Li;
Susan Shen;
Bickler, Philip;
Jacobson, Matthew P.;
Wu, Lani F.;
Altschuler, Steven J.

Publication type:

Article

The effects and mechanisms of isoliquiritigenin loaded nanoliposomes regulated AMPK/mTOR mediated glycolysis in colorectal cancer.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2020, v. 48, n. 1, p. 1231, doi. 10.1080/21691401.2020.1825092

By:

Wang, Gang;
Yu, Yang;
Wang, Yu-Zhu;
Yin, Pei-Hao;
Xu, Ke;
Zhang, Heng

Publication type:

Article

Engineering oxygen nanobubbles for the effective reversal of hypoxia.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. S318, doi. 10.1080/21691401.2018.1492420

By:

Khan, Muhammad Saad;
Hwang, Jangsun;
Seo, Youngmin;
Shin, Kyusoon;
Lee, Kyungwoo;
Park, Chanhwi;
Choi, Yonghyun;
Hong, Jong Wook;
Choi, Jonghoon

Publication type:

Article

Nano-gold displayed anti-inflammatory property via NF-kB pathways by suppressing COX-2 activity.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. 1149, doi. 10.1080/21691401.2018.1446968

By:

Khan, Mahmood Ahmad;
Khan, Mohd Jahir

Publication type:

Article

The association of HIF1A gene polymorphism and its expression with ischemic stroke.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99418-6

By:

Yang, Fengjiao;
Gu, Yun;
Yan, Ya;
Wang, Pengyu;
Wang, Min;
Chen, Jianjie;
Du, Xiaoshan;
Wang, Guangming

Publication type:

Article

2'-Epi-uscharin from the Latex of Calotropis gigantea with HIF-1 Inhibitory Activity.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04748

By:

Parhira, Supawadee;
Guo-Yuan Zhu;
Ren-Wang Jiang;
Liang Liu;
Li-Ping Bai;
Zhi-Hong Jiang

Publication type:

Article

HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03793

By:

Tao Zhao;
Yuxi Zhu;
Akiyo Morinibu;
Minoru Kobayashi;
Kazumi Shinomiya;
Satoshi Itasaka;
Michio Yoshimura;
Guozheng Guo;
Masahiro Hiraoka;
Hiroshi Harada

Publication type:

Article

Effect of Moderate Hepatic Impairment on the Pharmacokinetics of Vadadustat, an Oral Hypoxia‐Inducible Factor Prolyl Hydroxylase Inhibitor.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 8, p. 950, doi. 10.1002/cpdd.927

By:

Chavan, Ajit;
Burke, Leontia;
Sawant, Rishikesh;
Navarro‐Gonzales, Pamela;
Vargo, Dennis;
Paulson, Susan K.

Publication type:

Article

Leptin–VEGF crosstalk in excess body mass and related disorders: A systematic review.

Published in:

Obesity Reviews, 2023, v. 24, n. 8, p. 1, doi. 10.1111/obr.13575

By:

Skrypnik, Damian;
Skrypnik, Katarzyna;
Suliburska, Joanna;
Bogdański, Paweł

Publication type:

Article

Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1575332

By:

Liao, Bin;
Wang, Pan;
Gong, Sheng;
Zhao, Lu;
Liu, Jie;
Wu, Nan

Publication type:

Article

Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1530715

By:

Zhu, Genbao;
Jiang, Zhiming;
Zhu, Niuping;
Wang, Donghui;
Guo, Tianpeng;
Meng, Yiqing;
Zhu, Yi;
Tan, Kemeng;
Hu, Mengxue;
Tang, Heng;
Wang, Xuannian

Publication type:

Article

Role, Targets and Regulation of (de)nitrosylation in Malignancy.

Published in:

Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00334

By:

Rizza, Salvatore;
Filomeni, Giuseppe

Publication type:

Article