Works about HYDROXYSTEROID dehydrogenases

Results: 282

A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity.

Published in:

PLoS Biology, 2012, v. 10, n. 4, p. 1, doi. 10.1371/journal.pbio.1001305

By:

Wollam, Joshua;
Magner, Daniel B.;
Magomedova, Lilia;
Rass, Elisabeth;
Shen, Yidong;
Rottiers, Veerle;
Habermann, Bianca;
Cummins, Carolyn L.;
Antebi, Adam

Publication type:

Article

Engineering a hydroxysteroid dehydrogenase to improve its soluble expression for the asymmetric reduction of cortisone to 11β-hydrocortisone.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 21, p. 8879, doi. 10.1007/s00253-014-5967-1

By:

Zhang, Dalong;
Zhang, Rui;
Zhang, Jie;
Chen, Liying;
Zhao, Chunxia;
Dong, Wenyue;
Zhao, Qing;
Wu, Qiaqing;
Zhu, Dunming

Publication type:

Article

One-step synthesis of 12-ketoursodeoxycholic acid from dehydrocholic acid using a multienzymatic system.

Published in:

Applied Microbiology & Biotechnology, 2013, v. 97, n. 2, p. 633, doi. 10.1007/s00253-012-4340-5

By:

Liu, Luo;
Braun, Michael;
Gebhardt, Gabi;
Weuster-Botz, Dirk;
Gross, Ralf;
Schmid, Rolf

Publication type:

Article

Novel whole-cell biocatalysts with recombinant hydroxysteroid dehydrogenases for the asymmetric reduction of dehydrocholic acid.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 95, n. 6, p. 1457, doi. 10.1007/s00253-012-4072-6

By:

Braun, Michael;
Sun, Boqiao;
Anselment, Bernd;
Weuster-Botz, Dirk

Publication type:

Article

Interspecies pregnancy between Ovis canadensis mexicana and Ovis aries with reduced placental P450scc expression and intrauterine growth restriction.

Published in:

Veterinaria México OA, 2024, v. 11, p. 1, doi. 10.22201/fmvz.24486760e.2024.1262

By:

Chávez-García, Araceli;
Cabrera-Reyes, Erika Alejandra;
Molina-Salinas, Gladys;
Olvera-Sánchez, Sofía;
Mejía-Villanueva, Octavio;
Martínez, Federico;
Cerbón, Marco

Publication type:

Article

Rapidly directional biotransformation of tauroursodeoxycholic acid through engineered Escherichia coli.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2017, v. 44, n. 7, p. 1073, doi. 10.1007/s10295-017-1935-y

By:

Shi, Jie;
Wang, Jie;
Yu, Lu;
Yang, Li;
Zhao, Shujuan;
Wang, Zhengtao

Publication type:

Article

Effects of trilostane and fipronil on the reproductive axis in an early life stage of the Japanese medaka ( Oryzias latipes).

Published in:

Ecotoxicology, 2014, v. 23, n. 6, p. 1044, doi. 10.1007/s10646-014-1248-0

By:

Sun, Liwei;
Jin, Rong;
Peng, Zuhua;
Zhou, Qiwei;
Qian, Haifeng;
Fu, Zhengwei

Publication type:

Article

The Hepato-Hypothalamic-Pituitary-Adrenal-Renal Axis: Mathematical Modeling of Cortisol’s Production, Metabolism, and Seasonal Variation.

Published in:

Journal of Biological Rhythms, 2017, v. 32, n. 5, p. 469, doi. 10.1177/0748730417729929

By:

Pierre, Kamau;
Schlesinger, Naomi;
Androulakis, Ioannis P.

Publication type:

Article

INVITED REVIEW: The usefulness of measuring glucocorticoids for assessing animal welfare.

Published in:

Journal of Animal Science, 2016, v. 94, n. 2, p. 457, doi. 10.2527/jas.2015-9645

By:

Ralph, C. R.;
Tilbrook, A. J.

Publication type:

Article

Th2 cells and Th17 cells in the development of endometriosis - possible roles of interleukin-4 and interleukin-17A.

Published in:

Journal of Endometriosis & Pelvic Pain Disorders, 2016, v. 8, n. 4, p. 136, doi. 10.5301/je.5000257

By:

Yutaka Osuga;
Yasushi Hirota;
Tetsuya Hirata;
Masashi Takamura;
Yoko Urata;
Miyuki Harada;
Gentaro Izumi;
Tomoyuki Fujii;
Kaori Koga

Publication type:

Article

The effect of bisphenol A on testicular steroidogenesis and its amelioration by quercetin: an in vivo and in silico approach.

Published in:

Toxicology Research, 2018, v. 7, n. 1, p. 22, doi. 10.1039/c7tx00161d

By:

Samova, Sanman;
Patel, Chirag N.;
Doctor, Hetal;
Pandya, Himanshu A.;
Verma, R. J.

Publication type:

Article

Effect of quinine-loaded polysorbate-coated nanocapsules on male and female reproductive systems of rats.

Published in:

Toxicology Research, 2016, v. 5, n. 6, p. 1561, doi. 10.1039/c6tx00203j

By:

Izaguirry, Aryele Pinto;
Pavin, Natasha Frasson;
Soares, Melina Bucco;
Spiazzi, Cristiano Chiapinotto;
Araújo, Flávio Arci;
Michels, Luana Roberta;
Leivas, Fábio Gallas;
Brum, Daniela dos Santos;
Haas, Sandra Elisa;
Santos, Francielli Weber

Publication type:

Article

Lead aggravates the diabetic-induced reproductive toxicity in male Wistar rats.

Published in:

Toxicology Research, 2016, v. 5, n. 5, p. 1465, doi. 10.1039/c6tx00099a

By:

Reddy, K. Pratap;
Narayana Rao, Madamsetti;
Murthy, J. S. R.;
Reddy, P. Sreenivasula

Publication type:

Article

Safety, efficacy and weight effect of two 11β- HSD1 inhibitors in metformin-treated patients with type 2 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2014, v. 16, n. 11, p. 1070, doi. 10.1111/dom.12317

By:

Heise, T.;
Morrow, L.;
Hompesch, M.;
Häring, H.‐U.;
Kapitza, C.;
Abt, M.;
Ramsauer, M.;
Magnone, M.‐C.;
Fuerst‐Recktenwald, S.

Publication type:

Article

Differences between men and women in the regulation of adipose 11β- HSD1 and in its association with adiposity and insulin resistance.

Published in:

Diabetes, Obesity & Metabolism, 2013, v. 15, n. 11, p. 1056, doi. 10.1111/dom.12137

By:

deSchoolmeester, J.;
Palming, J.;
Persson, T.;
Pereira, M. J.;
Wallerstedt, E.;
Brown, H.;
Gill, D.;
Renström, F.;
Lundgren, M.;
Svensson, M. K.;
Rees, A.;
Eriksson, J. W.

Publication type:

Article

11 β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.

Published in:

Diabetes, Obesity & Metabolism, 2012, v. 14, n. 10, p. 869, doi. 10.1111/j.1463-1326.2012.01582.x

By:

Pereira, C. D.;
Azevedo, I.;
Monteiro, R.;
Martins, M. J.

Publication type:

Article

Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.

Published in:

Molecular Informatics, 2014, v. 33, n. 1, p. 15, doi. 10.1002/minf.201300063

By:

Vuorinen, Anna;
Nashev, Lyubomir G.;
Odermatt, Alex;
Rollinger, Judith M.;
Schuster, Daniela

Publication type:

Article

Systemic overexpression of the 11β‑HSD1 promotes endoplasmic reticulum stress in multiple tissues and the development of metabolic syndrome in mice.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 5, p. 7738, doi. 10.3892/mmr.2017.7530

By:

CHENXIAO LI;
JIHAN XIA;
WENJUAN ZHU;
LEILEI XIN;
CUIPING AN;
SHULIN YANG;
KUI LI

Publication type:

Article

RETRACTION.

Published in:: 2016
Publication type:: Correction Notice

Blockade of 11β-hydroxysteroid dehydrogenase type 1 enzyme inhibits experimental collagenase-induced osteoarthritis.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 3, p. 2071, doi. 10.3892/mmr.2014.2983

By:

FAXIN LI;
CHUANWU QIAO;
YI LI;
JIE ZHU;
JIAN CHEN;
SHUYA GUO

Publication type:

Article

46,XY disorder of sex development due to 17-beta hydroxysteroid dehydrogenase type 3 deficiency: a plea for timely genetic testing.

Published in:

2016

By:

Grimbly, Chelsey;
Caluseriu, Oana;
Metcalfe, Peter;
Jetha, Mary M.;
Rosolowsky, Elizabeth T.

Publication type:

Case Study

Variants of 11β-hydroxysteroid dehydrogenase (HSD11B) gene type 1 and 2 in Chinese obese adolescents.

Published in:

2013

By:

Zou Chao Chun

Publication type:

Abstract

Two Moroccan Sisters Presenting with a Severe Salt-Wasting Form of Congenital Adrenal Hyperplasia but Normal Female Genitalia.

Published in:

2017

By:

Scaramuzzo, Rosa T.;
Menabò, Soara;
Baldazzi, Lilia;
Moscuzza, Francesca;
Saba, alessandro;
Balsamo, antonio;
Boldrini, antonio;
Ghirri, Paolo

Publication type:

Case Study

Polymorphisms in HSD17B1: Early Onset and Increased Risk of Alzheimer's Disease in Women with Down Syndrome.

Published in:

Current Gerontology & Geratrics Research, 2012, p. 1, doi. 10.1155/2012/361218

By:

Lee, Joseph H.;
Gurney, Susan;
Pang, Deborah;
Temkin, Alexis;
Park, Naeun;
Janicki, Sarah C.;
Zigman, Warren B.;
Silverman, Wayne;
Tycko, Benjamin;
Schupf, Nicole

Publication type:

Article

Functional Analysis of HSD17B3-Deficient Male Mice Reveals Roles for HSD17B7 and HSD17B12 in Testosterone Biosynthesis Open Access.

Published in:

Endocrinology, 2025, v. 166, n. 6, p. 1, doi. 10.1210/endocr/bqaf078

By:

Lawrence, Ben M;
O'Donnell, Liza;
Gannon, Anne-Louise;
Skerrett-Byrne, David A;
Parameswaran, Shanmathi;
Abbott, Imogen;
Smith, Sarah;
Handelsman, David J;
Rebourcet, Diane;
Smith, Lee B

Publication type:

Article

Evidence for expression of 11β-hydroxysteroid dehydrogenase type3 (HSD11B3/HSD11B1L) in neonatal pig testis.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 381, n. 1/2, p. 145, doi. 10.1007/s11010-013-1697-4

By:

Ohno, Shuji;
Nakagawara, Satomi;
Honda, Yoko;
Nakajin, Shizuo

Publication type:

Article

The effect of early-life stress and chronic high-sucrose diet on metabolic outcomes in female rats.

Published in:

Stress: The International Journal on the Biology of Stress, 2015, v. 18, n. 5, p. 524, doi. 10.3109/10253890.2015.1079617

By:

Maniam, Jayanthi;
Antoniadis, Christopher P.;
Morris, Margaret J.

Publication type:

Article

Regulation of glucocorticoid metabolism in the boar testis and caput epididymidis by the gonadotrophin-cAMP signalling pathway.

Published in:

Cell & Tissue Research, 2013, v. 352, n. 3, p. 751, doi. 10.1007/s00441-013-1613-y

By:

Cabrera-Sharp, Victoria;
Mirczuk, Samantha;
Shervill, Elaine;
Michael, Anthony;
Fowkes, Robert

Publication type:

Article

Modulation of 11β-hydroxysteroid dehydrogenase 1 by β2-adrenoceptor in the ischaemia-reperfused rat kidney.

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 9, p. 3456, doi. 10.1093/ndt/gfr701

By:

Nakamura, Akio;
Miyagawa, Makoto;
Yanagawa, Yukishige

Publication type:

Article

The Effects of Sertraline on Fathead Minnow ( Pimephales promelas) Growth and Steroidogenesis.

Published in:

Bulletin of Environmental Contamination & Toxicology, 2017, v. 98, n. 6, p. 753, doi. 10.1007/s00128-017-2079-5

By:

Carty, D.;
Hala, D.;
Huggett, D.

Publication type:

Article

Alteration of 11β-Hydroxysteroid Dehydrogenase Type 1 and Glucocorticoid Receptor by Ethanol in Rat Liver and Mouse Hepatoma Cells.

Published in:

Journal of Diabetes Research, 2013, p. 1, doi. 10.1155/2013/218102

By:

Zhaojie Meng;
Xueying Bao;
Ming Zhang;
Shengnan Wei;
Wenguang Chang;
Jing Li;
Li Chen;
Nyomba, B. L. Grégoire

Publication type:

Article

11β-hydroxysteroid dehydrogenases as targets in the treatment of steroid-associated femoral head necrosis using antler extract.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 1, p. 977, doi. 10.3892/etm.2017.5459

By:

Pu, Ribusurong;
Peng, Hao

Publication type:

Article

Increased 3β-hydroxysteroid dehydrogenase 2 and 17α-hydroxylase activities in a virilized adolescent female with adrenal adenoma: A case report.

Published in:

2016

By:

GUOQING YANG;
JINGTAO DOU;
XIAOLIN ZHANG;
WEIJUN GU;
ZHAOHUI LV;
JIN DU;
JIANMING BA;
YIMING MU;
JUMING LU

Publication type:

Case Study

Human 3 β-hydroxysteroid dehydrogenase type 1 in human breast cancer: clinical significance and prognostic associations.

Published in:

Cancer Medicine, 2016, v. 5, n. 7, p. 1405, doi. 10.1002/cam4.708

By:

Hanamura, Toru;
Ito, Tokiko;
Kanai, Toshiharu;
Maeno, Kazuma;
Shimojo, Yasuyo;
Uehara, Takeshi;
Suzuki, Takashi;
Hayashi, Shin‐ichi;
Ito, Ken‐ichi

Publication type:

Article

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

Published in:

Andrology, 2016, v. 4, n. 2, p. 335, doi. 10.1111/andr.12150

By:

Di‐Luoffo, M.;
Brousseau, C.;
Tremblay, J. J.

Publication type:

Article

Time course and role of luteinizing hormone and follicle-stimulating hormone in the expansion of the Leydig cell population at the time of puberty in the rhesus monkey ( Macaca mulatta).

Published in:

Andrology, 2014, v. 2, n. 6, p. 924, doi. 10.1111/andr.275

By:

Verhagen, I.;
Ramaswamy, S.;
Teerds, K. J.;
Keijer, J.;
Plant, T. M.

Publication type:

Article

Molecular Mechanism Study on Stereo-Selectivity of α or β Hydroxysteroid Dehydrogenases.

Published in:

Crystals (2073-4352), 2021, v. 11, n. 3, p. 224, doi. 10.3390/cryst11030224

By:

Gao, Miaomiao;
Nie, Kaili;
Qin, Meng;
Xu, Haijun;
Wang, Fang;
Liu, Luo;
Angelov, Borislav

Publication type:

Article

Site-specific methylation of placental HSD11B2 gene promoter is related to intrauterine growth restriction.

Published in:

European Journal of Human Genetics, 2014, v. 22, n. 6, p. 734, doi. 10.1038/ejhg.2013.226

By:

Zhao, Yan;
Gong, Xia;
Chen, Li;
Li, Luxi;
Liang, Yuan;
Chen, ShangQin;
Zhang, Yunhui

Publication type:

Article

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

Published in:

BMC Research Notes, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-0500-7-119

By:

Boucher, Eric;
Provost, Pierre R.;
Tremblay, Yves

Publication type:

Article

Mouse 11β-Hydroxysteroid Dehydrogenase Type 2 for Human Application: Homology Modeling, Structural Analysis and Ligand-Receptor Interaction.

Published in:

Cancer Informatics, 2011, n. 10, p. 287, doi. 10.4137/CIN.S8725

By:

Yamaguchi, Hideaki;
Akitaya, Tatsuo;
Kidachi, Yumi;
Kamiie, Katsuyoshi;
Noshita, Toshiro;
Umetsu, Hironori;
Ryoyama, Kazuo

Publication type:

Article

Down-regulated HSDL2 expression suppresses cell proliferation and promotes apoptosis in papillary thyroid carcinoma.

Published in:

Bioscience Reports, 2019, v. 39, n. 6, p. 1, doi. 10.1042/BSR20190425

By:

Jing Zeng;
Xiao Ma;
Jinjing Wang;
Ran Liu;
Yun Shao;
Yanwei Hou;
Zhiyuan Li;
Yi Fang

Publication type:

Article

Glucocorticoids Induces Apoptosis in Chondrocytes Through the Regulation of 11β-Hydroxysteroid Dehydrogenases (11β-HSDs).

Published in:

International Journal of Peptide Research & Therapeutics, 2018, v. 24, n. 4, p. 519, doi. 10.1007/s10989-017-9639-8

By:

Bu, Xiangpeng;
Zhou, Fuling;
Zhang, Hao;
Pan, Zhenyu

Publication type:

Article

Identification of a Principal mRNA Species for Human 3α-Hydroxysteroid Dehydrogenase Isoform (AKR1C3) That Exhibits High Prostaglandin D2 11-Ketoreductase Activity1.

Published in:

Journal of Biochemistry, 1998, v. 124, n. 5, p. 940, doi. 10.1093/oxfordjournals.jbchem.a022211

By:

Matsuura, Kazuya;
Shiraishi, Hiroaki;
Hara, Akira;
Sato, Kumiko;
Deyashiki, Yoshihiro;
Ninomiya, Mitsuo;
Sakai, Syunsuke

Publication type:

Article

Synthesis of TUDCA from chicken bile: immobilized dual-enzymatic system for producing artificial bear bile substitute.

Published in:

Microbial Cell Factories, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12934-024-02592-x

By:

Shijing, Tang;
Yinping, Pan;
Qiong, Yang;
Deshuai, Lou;
Liancai, Zhu;
Jun, Tan;
Shaoyong, Liu;
Bochu, Wang

Publication type:

Article

HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer.

Published in:

2018

By:

Alyamani, Mohammad;
Emamekhoo, Hamid;
Sunho Park;
Taylor, Jennifer;
Almassi, Nima;
Upadhyay, Sunil;
Tyler, Allison;
Berk, Michael P.;
Bo Hu;
Tae Hyun Hwang;
Douglas Figg, William;
Peer, Cody J.;
Chien, Caly;
Koshkin, Vadim S.;
Mendiratta, Prateek;
Grivas, Petros;
Rini, Brian;
Garcia, Jorge;
Auchus, Richard J.;
Sharifi, Nima

Publication type:

journal article

Corrigendum: Potent and selective inhibitors of 11β‐hydroxysteroid dehydrogenase type 1 labeled with carbon‐13 and carbon‐14.

Published in:

2018

By:

Latli, Bachir;
Hrapchak, Matt;
Savoie, Jolaine;
Zhang, Yongda;
Busacca, Carl A.;
Senanayake, Chris H.

Publication type:

Correction Notice

Potent and selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 labeled with carbon-13 and carbon-14.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2017, v. 60, n. 9, p. 420, doi. 10.1002/jlcr.3518

By:

Latli, Bachir;
Hrapchak, Matt;
Savoie, Jolaine;
Zhang, Yongda;
Busacca, Carl A.;
Senanayake, Chris H.

Publication type:

Article

The syntheses of [13C6] and [phenyl-14C(U)]BMS-816336, an inhibitor of 11β-hydroxysteroid dehydrogenase type 1, for type 2 diabetes.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2017, v. 60, n. 8, p. 357, doi. 10.1002/jlcr.3500

By:

Maxwell, Brad D.

Publication type:

Article

The synthesis and analysis of [phenyl-14C(U)]BMS-770767 and [13C6]BMS-770767 for use in discovery biotransformation, human ADME and bioanalytical studies.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2016, v. 59, n. 14, p. 657, doi. 10.1002/jlcr.3428

By:

Maxwell, Brad D.;
Bonacorsi, Samuel J.

Publication type:

Article

Variants of HSD11B2 gene in hypertensive disorders of pregnancy.

Published in:

2017

By:

Kosicka, Katarzyna;
Siemiątkowska, Anna;
Pękal, Agnieszka;
Majchrzak-Celińska, Aleksandra;
Bręborowicz, Grzegorz;
Krzyścin, Mariola;
Główka, Franciszek

Publication type:

journal article