Works about HISTONE demethylases

Results: 423

Unprogrammed epigenetic variation mediated by stochastic formation of ectopic heterochromatin.

Published in:

Current Genetics, 2020, v. 66, n. 2, p. 319, doi. 10.1007/s00294-019-01031-4

By:

Sorida, Masato;
Murakami, Yota

Publication type:

Article

KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02020-4

By:

Wang, Yumin;
Liu, Shiqian;
Wang, Yan;
Li, Baibei;
Liang, Jiaming;
Chen, Yu;
Tang, Bo;
Yu, Shuiping;
Wang, Hongquan

Publication type:

Article

NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 4, p. 442, doi. 10.3390/jcm8040442

By:

Etani, Toshiki;
Naiki, Taku;
Naiki-Ito, Aya;
Suzuki, Takayoshi;
Iida, Keitaro;
Nozaki, Satoshi;
Kato, Hiroyuki;
Nagayasu, Yuko;
Suzuki, Shugo;
Kawai, Noriyasu;
Yasui, Takahiro;
Takahashi, Satoru

Publication type:

Article

The Roles of Histone Demethylase Jmjd3 in Osteoblast Differentiation and Apoptosis.

Published in:

Journal of Clinical Medicine, 2017, v. 6, n. 3, p. 24, doi. 10.3390/jcm6030024

By:

Di Yang;
Bo Yu;
Haiyan Sun;
Lihong Qiu

Publication type:

Article

Shorting vorasidenib for IDH mutant low-grade glioma.

Published in:

2024

By:

Wong, Eric T

Publication type:

Editorial

The diagnostic performance of lysine(K)-specific demethylase 6B (KDM6B) in non-small cell lung cancer.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2019, v. 47, n. 1, p. 2155, doi. 10.1080/21691401.2019.1620758

By:

Ge, Ting;
Zhou, Ying;
Lu, Hongmin

Publication type:

Article

Epigenetic Regulation by Chromatin Activation Mark H3K4me3 in Primate Progenitor Cells within Adult Neurogenic Niche.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05371

By:

Sandstrom, Richard S.;
Foret, Michael R.;
Grow, Douglas A.;
Haugen, Eric;
Rhodes, Christopher T.;
Cardona, Astrid E.;
Phelix, Clyde F.;
Yufeng Wang;
Berger, Mitchel S.;
Chin-Hsing Annie Lin

Publication type:

Article

PHF8 and REST/NRSF co-occupy gene promoters to regulate proximal gene expression.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05008

By:

Juan Wang;
Xueqiu Lin;
Su Wang;
Chenfei Wang;
Qixuan Wang;
Xikun Duan;
Peng Lu;
Qian Wang;
Chengyang Wang;
Liu, X. Shirley;
Jinyan Huang

Publication type:

Article

Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02894

By:

Tsurumi, Amy;
Dutta, Pranabanada;
Shian-Jang Yan;
Robin Sheng;
Willis X. Li

Publication type:

Article

Arabidopsis histone demethylases LDL1 and LDL2 control primary seed dormancy by regulating DELAY OF GERMINATION 1 and ABA signaling-related genes.

Published in:

Frontiers in Plant Science, 2015, v. 6, p. 1, doi. 10.3389/fpls.2015.00159

By:

Minglei Zhao;
Songguang Yang;
Xuncheng Liu;
Keqiang Wu

Publication type:

Article

Functional diversity of 2-oxoglutarate/Fe(II)-dependent dioxygenases in plant metabolism.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00524

By:

Farrow, Scott C.;
Facchini, Peter J.

Publication type:

Article

Over-expression of histone H3K4 demethylase gene JMJ15 enhances salt tolerance in Arabidopsis.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00290

By:

Yuan Shen;
e Silva, Natalia Conde;
Audonnet, Laure;
Servet, Caroline;
Wei Wei;
Dao-Xiu Zhou

Publication type:

Article

Relationship between histone demethylase LSD family and development and prognosis of gastric cancer .

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1170773

By:

Liyan Dong;
Jiaxing Zhu;
Anyi Deng;
Junping Wei;
Jiawei Li;
Xinru Mao;
Zhenghu Jia

Publication type:

Article

The Role of Histone Lysine Methylation in the Response of Mammalian Cells to Ionizing Radiation.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.639602

By:

Di Nisio, Elena;
Lupo, Giuseppe;
Licursi, Valerio;
Negri, Rodolfo

Publication type:

Article

The Role of Histone Lysine Methylation in the Response of Mammalian Cells to Ionizing Radiation.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.639602

By:

Di Nisio, Elena;
Lupo, Giuseppe;
Licursi, Valerio;
Negri, Rodolfo

Publication type:

Article

Prospective Review of Mesenchymal Stem Cells Differentiation into Osteoblasts.

Published in:

Orthopaedic Surgery, 2017, v. 9, n. 1, p. 13, doi. 10.1111/os.12304

By:

Garg, Priyanka;
Mazur, Matthew M;
Buck, Amy C;
Wandtke, Meghan E;
Liu, Jiayong;
Ebraheim, Nabil A

Publication type:

Article

Pharmacological targeting of KDM6A and KDM6B, as a novel therapeutic strategy for treating craniosynostosis in Saethre-Chotzen syndrome.

Published in:

Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. 1, doi. 10.1186/s13287-020-02051-5

By:

Pribadi, Clara;
Camp, Esther;
Cakouros, Dimitrios;
Anderson, Peter;
Glackin, Carlotta;
Gronthos, Stan

Publication type:

Article

Cooperation between ETS variant 2 and Jumonji domain‑containing 2 histone demethylases.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 4, p. 5518, doi. 10.3892/mmr.2018.8507

By:

Li, Xiaomeng;
Moon, Gene;
Shin, Sook;
Zhang, Bin;
Janknecht, Ralf

Publication type:

Article

Evaluation of Histone Demethylase Inhibitor ML324 and Acyclovir against Cyprinid herpesvirus 3 Infection.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 1, p. 163, doi. 10.3390/v15010163

By:

Matsuoka, Shelby;
Petri, Gloria;
Larson, Kristen;
Behnke, Alexandra;
Wang, Xisheng;
Peng, Muhui;
Spagnoli, Sean;
Lohr, Christiane;
Milston-Clements, Ruth;
Divilov, Konstantin;
Jin, Ling

Publication type:

Article

KSHV ORF59 and PAN RNA Recruit Histone Demethylases to the Viral Chromatin during Lytic Reactivation.

Published in:

Viruses (1999-4915), 2020, v. 12, n. 4, p. 420, doi. 10.3390/v12040420

By:

Hiura, Kayla;
Strahan, Roxanne;
Uppal, Timsy;
Prince, Brian;
Rossetto, Cyprian C.;
Verma, Subhash C.

Publication type:

Article

Contribution of H3K4 demethylase KDM5B to nucleosome organization in embryonic stem cells revealed by micrococcal nuclease sequencing.

Published in:

Epigenetics & Chromatin, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13072-019-0266-9

By:

Kurup, Jiji T.;
Campeanu, Ion J.;
Kidder, Benjamin L.

Publication type:

Article

Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8.

Published in:

Epigenetics & Chromatin, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13072-018-0231-z

By:

Tsusaka, Takeshi;
Kikuchi, Masaki;
Shimazu, Tadahiro;
Suzuki, Takehiro;
Sohtome, Yoshihiro;
Akakabe, Mai;
Sodeoka, Mikiko;
Dohmae, Naoshi;
Umehara, Takashi;
Shinkai, Yoichi

Publication type:

Article

Assessing histone demethylase inhibitors in cells: lessons learned.

Published in:

Epigenetics & Chromatin, 2017, v. 10, p. 1, doi. 10.1186/s13072-017-0116-6

By:

Hatch, Stephanie B.;
Yapp, Clarence;
Montenegro, Raquel C.;
Savitsky, Pavel;
Gamble, Vicki;
Tumber, Anthony;
Ruda, Gian Filippo;
Bavetsias, Vassilios;
Fedorov, Oleg;
Atrash, Butrus;
Raynaud, Florence;
Lanigan, Rachel;
Carmichael, LeAnne;
Tomlin, Kathy;
Burke, Rosemary;
Westaway, Susan M.;
Brown, Jack A.;
Prinjha, Rab K.;
Martinez, Elisabeth D.;
Oppermann, Udo

Publication type:

Article

The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3.

Published in:

Epigenetics & Chromatin, 2016, v. 9, p. 1, doi. 10.1186/s13072-016-0053-9

By:

Gajan, Ambikai;
Barnes, Valerie L.;
Mengying Liu;
Saha, Nirmalya;
Pile, Lori A.

Publication type:

Article

Aberrant Histone Methylation in Patients with Graves' Disease.

Published in:

International Journal of Endocrinology, 2019, p. 1, doi. 10.1155/2019/1454617

By:

Yan, Ni;
Mu, Kaida;
An, Xiao-fei;
Li, Ling;
Qin, Qiu;
Song, Rong-hua;
Yao, Qiu-ming;
Shao, Xiao-qing;
Zhang, Jin-an

Publication type:

Article

Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives.

Published in:

Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0279-9

By:

Yongcheng Song;
Fangrui Wu;
Jingyu Wu

Publication type:

Article

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations.

Published in:

Journal of Hematology & Oncology, 2014, v. 7, n. 1, p. 174, doi. 10.1186/s13045-014-0094-0

By:

Skvarova Kramarzova, Karolina;
Fiser, Karel;
Mejstrikova, Ester;
Rejlova, Katerina;
Zaliova, Marketa;
Fornerod, Maarten;
Drabkin, Harry A.;
van den Heuvel-Eibrink, Marry M.;
Stary, Jan;
Trka, Jan;
Starkova, Julia

Publication type:

Article

Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus.

Published in:

PLoS ONE, 2022, v. 17, n. 12, p. 1, doi. 10.1371/journal.pone.0271145

By:

Gilmore, Sarah A.;
Tam, Danny;
Cheung, Tara L.;
Snyder, Chelsea;
Farand, Julie;
Dick, Ryan;
Matles, Mike;
Feng, Joy Y.;
Ramirez, Ricardo;
Li, Li;
Yu, Helen;
Xu, Yili;
Barnes, Dwight;
Czerwieniec, Gregg;
Brendza, Katherine M.;
Appleby, Todd C.;
Birkus, Gabriel;
Willkom, Madeleine;
Kobayashi, Tetsuya;
Paoli, Eric

Publication type:

Article

The role of PHF8 and TLR4 in osteogenic differentiation of periodontal ligament cells in inflammatory environment.

Published in:

2021

By:

Liu, Zhao;
He, Yiheng;
Xu, Chenrong;
Li, Jianjia;
Zeng, Shuguang;
Yang, Xi;
Han, Qianqian

Publication type:

journal article

The role of histone demethylases in cancer therapy

Published in:

Molecular Oncology, 2012, v. 6, n. 6, p. 683, doi. 10.1016/j.molonc.2012.07.004

By:

Hoffmann, Inga;
Roatsch, Martin;
Schmitt, Martin L.;
Carlino, Luca;
Pippel, Martin;
Sippl, Wolfgang;
Jung, Manfred

Publication type:

Article

Mizl Controls Schwann Cell Proliferation via H3K36<sup>me2</sup> Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 858, doi. 10.1523/JNEUROSCI.0843-17.2017

By:

Fuhrmann, David;
Elsässer, Hans-Peter;
Nist, Andrea;
Mernberger, Marco;
Stiewe, Thorsten

Publication type:

Article

Neuronal Kmt2a/Mll1 Histone Methyltransferase Is Essential for Prefrontal Synaptic Plasticity and Working Memory.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 13, p. 5097, doi. 10.1523/JNEUROSCI.3004-14.2015

By:

Jakovcevski, Mira;
Hongyu Ruan;
Shen, Erica Y.;
Dince, Aslihan;
Javidfar, Behnam;
Qi Ma;
Peter, Cyril J.;
Cheung, Iris;
Mitchell, Amanda C.;
Yan Jiang;
Lin, Cong L.;
Pothula, Venu;
Stewart, A. Francis;
Ernst, Patricia;
Wei-Dong Yao;
Akbarian, Schahram

Publication type:

Article

Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells.

Published in:

British Journal of Cancer, 2014, v. 110, n. 6, p. 1645, doi. 10.1038/bjc.2014.48

By:

Hirata, H;
Hinoda, Y;
Shahryari, V;
Deng, G;
Tanaka, Y;
Tabatabai, Z L;
Dahiya, R

Publication type:

Article

Jumonji Domain–containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility.

Published in:

Endocrinology, 2022, v. 163, n. 5, p. 1, doi. 10.1210/endocr/bqac047

By:

Roy, Sambit;
Sinha, Niharika;
Huang, Binbin;
Cline-Fedewa, Holly;
Gleicher, Norbert;
Wang, Jianrong;
Sen, Aritro

Publication type:

Article

Comparative genome-wide identification and characterization of SET domain-containing and JmjC domain-containing proteins in piroplasms.

Published in:

BMC Genomics, 2024, v. 25, p. 1, doi. 10.1186/s12864-024-10731-2

By:

Liang, Qindong;
Zhang, Shangdi;
Liu, Zeen;
Wang, Jinming;
Yin, Hong;
Guan, Guiquan;
You, Chongge

Publication type:

Article

Prognostic significance of RBP2-H1 variant of JARID1B in melanoma.

Published in:

2017

By:

Kuźbicki, Łukasz;
Lange, Dariusz;
Stanek-Widera, Agata;
Chwirot, Barbara W.

Publication type:

journal article

JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression.

Published in:

2017

By:

Yi Su;
Qiu-hong Yu;
Xiang-yun Wang;
Li-ping Yu;
Zong-feng Wang;
Ying-chun Cao;
Jian-dong Li;
Su, Yi;
Yu, Qiu-Hong;
Wang, Xiang-Yun;
Yu, Li-Ping;
Wang, Zong-Feng;
Cao, Ying-Chun;
Li, Jian-Dong

Publication type:

journal article

Histone Lysine Demethylases and Their Functions in Plants.

Published in:

Plant Molecular Biology Reporter, 2014, v. 32, n. 2, p. 558, doi. 10.1007/s11105-013-0673-1

By:

Luo, Ming;
Hung, Fu-Yu;
Yang, Songguang;
Liu, Xuncheng;
Wu, Keqiang

Publication type:

Article

BcJMJ30, the Gene Encoding jmjC Domain-Containing Histone Demethylase Is Associated with Pollen Development and Fertilization in Brassica campestris ssp. chinensis.

Published in:

Plant Molecular Biology Reporter, 2012, v. 30, n. 3, p. 529, doi. 10.1007/s11105-011-0356-8

By:

Li, Yifei;
Qiu, Lin;
Huang, Li;
Cao, Jiashu

Publication type:

Article

Front Cover: Origins of Catalysis in Non‐Heme Fe(II)/2‐Oxoglutarate‐Dependent Histone Lysine Demethylase KDM4A with Differently Methylated Histone H3 Peptides (Chem. Eur. J. 3/2025).

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 3, p. 1, doi. 10.1002/chem.202580301

By:

Devadas, Sudheesh;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
Varada, Bhargav;
White, Walter;
Sommer, Ethan;
Campbell, Kylin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Origins of Catalysis in Non‐Heme Fe(II)/2‐Oxoglutarate‐Dependent Histone Lysine Demethylase KDM4A with Differently Methylated Histone H3 Peptides.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 3, p. 1, doi. 10.1002/chem.202403989

By:

Devadas, Sudheesh;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
Varada, Bhargav;
White, Walter;
Sommer, Ethan;
Campbell, Kylin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Cover Feature: Catalysis by KDM6 Histone Demethylases – A Synergy between the Non‐Heme Iron(II) Center, Second Coordination Sphere, and Long‐Range Interactions (Chem. Eur. J. 51/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 51, p. 1, doi. 10.1002/chem.202302510

By:

Rifayee, Simahudeen Bathir Jaber Sathik;
Chaturvedi, Shobhit S.;
Warner, Cait;
Wildey, Jon;
White, Walter;
Thompson, Martin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Catalysis by KDM6 Histone Demethylases – A Synergy between the Non‐Heme Iron(II) Center, Second Coordination Sphere, and Long‐Range Interactions.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 51, p. 1, doi. 10.1002/chem.202301305

By:

Rifayee, Simahudeen Bathir Jaber Sathik;
Chaturvedi, Shobhit S.;
Warner, Cait;
Wildey, Jon;
White, Walter;
Thompson, Martin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

What Is the Catalytic Mechanism of Enzymatic Histone N‐Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field?

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 46, p. 11827, doi. 10.1002/chem.202101174

By:

Ramanan, Rajeev;
Waheed, Sodiq O.;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Jumonji family histone demethylases in neural development.

Published in:

Cell & Tissue Research, 2015, v. 359, n. 1, p. 87, doi. 10.1007/s00441-014-1924-7

By:

Fueyo, Raquel;
García, María;
Martínez-Balbás, Marian

Publication type:

Article

Expression of histone H3 lysine 4 methylation and its demethylases in the developing mouse testis.

Published in:

Cell & Tissue Research, 2014, v. 358, n. 3, p. 875, doi. 10.1007/s00441-014-1991-9

By:

Zhang, Liuping;
Wang, Jie;
Pan, Yaoqian;
Jin, Jie;
Sang, Jianrong;
Huang, Pan;
Shao, Genbao

Publication type:

Article

Histone demethylase KDM4A mediating macrophage polarization: A potential mechanism of trichloroethylene induced liver injury.

Published in:

Cell Biology International, 2024, v. 48, n. 8, p. 1148, doi. 10.1002/cbin.12187

By:

Zhang, Jiaxiang;
Huang, Hua;
Ding, Baiwang;
Liu, Zhibing;
Chen, Daojun;
Li, Shulong;
Shen, Tong;
Zhu, Qixing

Publication type:

Article

Triple Combinations of Histone Lysine Demethylase Inhibitors with PARP1 Inhibitor–Olaparib and Cisplatin Lead to Enhanced Cytotoxic Effects in Head and Neck Cancer Cells.

Published in:

Biomedicines, 2024, v. 12, n. 6, p. 1359, doi. 10.3390/biomedicines12061359

By:

Dorna, Dawid;
Kleszcz, Robert;
Paluszczak, Jarosław

Publication type:

Article

IDH Mutations in Glioma: Double-Edged Sword in Clinical Applications?

Published in:

Biomedicines, 2021, v. 9, n. 7, p. 799, doi. 10.3390/biomedicines9070799

By:

Kayabolen, Alisan;
Yilmaz, Ebru;
Bagci-Onder, Tugba

Publication type:

Article

Expression ratio of histone demethylase KDM3A to protamine-1 mRNA is predictive of successful testicular sperm extraction in men with obstructive and non-obstructive azoospermia.

Published in:

Andrology, 2016, v. 4, n. 3, p. 492, doi. 10.1111/andr.12164

By:

Javadirad, S. M.;
Hojati, Z.;
Ghaedi, K.;
Nasr‐Esfahani, M. H.

Publication type:

Article