Works about HISTONE deacetylase inhibitors

Results: 1850

Augmenting the Anti‐Leukemic Activity of the BCL‐2 Inhibitor Venetoclax Through Its Transformation Into Polypharmacologic Dual BCL‐2/HDAC1 and Dual BCL‐2/HDAC6 Inhibitors.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70084

By:

Chan, Alexandria M.;
Eberly, Christian;
Drennen, Brandon;
Goodis, Christopher C.;
Wuyts, Zoe;
Civin, Curt I.;
Fletcher, Steven

Publication type:

Article

Chidamide, a Histone Deacetylase Inhibitor, Combined With R‐GemOx in Relapsed/Refractory Diffuse Large B‐Cell Lymphoma (TRUST): A Multicenter, Single‐Arm, Phase 2 Trial.

Published in:

Cancer Medicine, 2025, v. 14, n. 9, p. 1, doi. 10.1002/cam4.70919

By:

Zou, Qihua;
Zhang, Yuchen;
Zhou, Hui;
Lai, Yulin;
Cao, Yi;
Li, Zhiming;
Su, Ning;
Li, Wenyu;
Huang, Huiqiang;
Liu, Panpan;
Ye, Xu;
Wu, Yudan;
Tan, Huo;
Zheng, Runhui;
Wu, Bingyi;
Yang, Hui;
Zhong, Liye;
Lu, Yuhong;
Liang, Yang;
Sun, Peng

Publication type:

Article

The histone deacetylase inhibitor CT-101 flips the switch to fetal hemoglobin expression in sickle cell disease mice.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323550

By:

Takezaki, Mayuko;
Li, Biaoru;
Xu, Hongyan;
Patel, Nikhil;
Lucas, Rudolf;
Cerbone, Ryan E.;
Koti, Sivanagireddy;
Hendrick, Clifford L.;
Junker, Louis H.;
Pace, Betty S.

Publication type:

Article

Venetoclax confers synthetic lethality to chidamide in preclinical models with transformed follicular lymphoma.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01878-0

By:

Zhong, Mengya;
Pan, Guangchao;
Tan, Jinshui;
Yao, Jingwei;
Liu, Yating;
Huang, Jiewen;
Jiang, Yuelong;
Zhu, Depeng;
Zhao, Jintao;
Xu, Bing;
Zha, Jie

Publication type:

Article

MANJEET SINGH PRIZE.

Published in:: 2015
Publication type:: Abstract

Current Status of Healthy Human Skin Models: Can Histone Deacetylase Inhibitors Potentially Improve the Present Replacement Models?

Published in:

Skin Pharmacology & Physiology, 2013, v. 27, n. 1, p. 36, doi. 10.1159/000351363

By:

Lemper, M.;
Snykers, S.;
Vanhaecke, T.;
De Paepe, K.;
Rogiers, V.

Publication type:

Article

Studying the Cytotoxic Activity of Newly Designed and Synthesized HDAC Inhibitors Derivatives of Pentanoyl Anilide‐5‐Biguanide.

Published in:

Macromolecular Symposia, 2022, v. 401, n. 1, p. 1, doi. 10.1002/masy.202100346

By:

Sagheer, Othman Makki;
Mohammed, Mohammed Hassan;
Wadi, Jaafar S.;
Ibraheem, Zaid O.

Publication type:

Article

Masking the Bioactivity of Hydroxamic Acids by Coordination to Cobalt: Towards Bioreductive Anticancer Agents.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 46, p. 1, doi. 10.1002/chem.202401724

By:

Goodman, David M.;
Ritter, Cornelia U.;
Chen, Erin;
Tong, Kelvin K. H.;
Riisom, Mie;
Söhnel, Tilo;
Jamieson, Stephen M. F.;
Anderson, Robert F.;
Brothers, Penelope J.;
Ware, David C.;
Hartinger, Christian G.

Publication type:

Article

Bioorthogonal Drug Release from Nanometric Micelles in Living Cells.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 43, p. 1, doi. 10.1002/chem.202301359

By:

Madegard, Léa;
Girard, Melissa;
Yaw, Benjamin Riss;
Porte, Karine;
Audisio, Davide;
Papot, Sébastien;
Taran, Frédéric

Publication type:

Article

Epigenetic modification enhances ergot alkaloid production of Claviceps purpurea.

Published in:

Biotechnology Letters, 2019, v. 41, n. 12, p. 1439, doi. 10.1007/s10529-019-02750-x

By:

Chen, Jing-Jing;
Han, Meng-Yao;
Gong, Ting;
Qiao, Yun-Ming;
Yang, Jin-Ling;
Zhu, Ping

Publication type:

Article

Enhancement of human mesenchymal stem cell differentiation by combination treatment with 5-azacytidine and trichostatin A.

Published in:

Biotechnology Letters, 2016, v. 38, n. 1, p. 167, doi. 10.1007/s10529-015-1949-3

By:

Kim, Hye;
Kwon, Yong-Rim;
Bae, Yu-Jin;
Kim, Yoo-Jin

Publication type:

Article

Analysis of histone deacetylase inhibitor-induced responses in human periodontal ligament fibroblasts.

Published in:

Biotechnology Letters, 2013, v. 35, n. 1, p. 129, doi. 10.1007/s10529-012-0992-6

By:

Kim, Tae-Il;
Han, Ji-Eun;
Jung, Hong-Moon;
Oh, Joung-Hwan;
Woo, Kyung

Publication type:

Article

SAHA could inhibit TGF-β1/p38 pathway in MI-induced cardiac fibrosis through DUSP4 overexpression.

Published in:

Heart & Vessels, 2022, v. 37, n. 1, p. 152, doi. 10.1007/s00380-021-01900-4

By:

Wang, Kaihao;
Tang, Ruijie;
Wang, Siyuan;
Wang, Wenyao;
Zhang, Kuo;
Li, Jun;
Li, Ping;
Tang, Yi-Da

Publication type:

Article

Panobinostat, a histone deacetylase inhibitor, rescues the angiogenic potential of endothelial colony-forming cells in moyamoya disease.

Published in:

Child's Nervous System, 2019, v. 35, n. 5, p. 823, doi. 10.1007/s00381-019-04099-y

By:

Jangra, Anshika;
Choi, Seung Ah;
Koh, Eun Jung;
Moon, Youn Joo;
Wang, Kyu-Chang;
Phi, Ji Hoon;
Lee, Ji Yeoun;
Kim, Seung-Ki

Publication type:

Article

Valproic acid treatment response in vitro is determined by TP53 status in medulloblastoma.

Published in:

Child's Nervous System, 2018, v. 34, n. 8, p. 1497, doi. 10.1007/s00381-018-3817-7

By:

Oliveira, Indhira Dias;
Tesser-Gamba, Francine;
Saba-Silva, Nasjla;
Dastoli, Patrícia;
Mascaro-Cordeiro, Bruna;
Toledo, Silvia Regina Caminada;
Cavalheiro, Sergio;
Pavon, Lorena Favaro

Publication type:

Article

Design and synthesis of mono and bicyclic tetrapeptides thioester as potent inhibitor of histone deacetylases.

Published in:

Amino Acids, 2014, v. 46, n. 10, p. 2435, doi. 10.1007/s00726-014-1800-5

By:

Hoque, Md.;
Islam, Md.;
Kato, Tamaki;
Nishino, Norikazu;
Ito, Akihiro;
Yoshida, Minoru

Publication type:

Article

Cyclic tetrapeptides with -SS- bridging between amino acid side chains for potent histone deacetylases' inhibition.

Published in:

Amino Acids, 2013, v. 45, n. 4, p. 835, doi. 10.1007/s00726-013-1527-8

By:

Arai, Toru;
Ashraful Hoque, Md.;
Nishino, Norikazu;
Kim, Hyun-Jung;
Ito, Akihiro;
Yoshida, Minoru

Publication type:

Article

Evaluation of functional groups on amino acids in cyclic tetrapeptides in histone deacetylase inhibition.

Published in:

Amino Acids, 2012, v. 42, n. 6, p. 2103, doi. 10.1007/s00726-011-0947-6

By:

Islam, Md.;
Bhuiyan, Mohammed;
Nsiama, Tienabe;
Oishi, Naoto;
Kato, Tamaki;
Nishino, Norikazu;
Ito, Akihiro;
Yoshida, Minoru

Publication type:

Article

Comparative Study of the Effect of a DNA Methyltransferase Inhibitor and a Histone Deacetylase Inhibitor on Memory Formation Processes in Anterograde Amnesia.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 174, n. 1, p. 1, doi. 10.1007/s10517-022-05636-7

By:

Kozyrev, S. A.;
Nikitin, V. P.;
Solntseva, S. V.;
Nikitin, P. V.

Publication type:

Article

The Impact of Simultaneous Epigenetic and Epitranscriptomic Intervention in Breast Cancer Cells.

Published in:

Istanbul Gelisim University Journal of Health Sciences / İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, 2024, n. 23, p. 505, doi. 10.38079/igusabder.1469350

By:

YANAR, Sevinç;
DEVECİ ÖZKAN, Asuman;
BAL ALBAYRAK, Merve Gülşen;
BETTS, Zeynep

Publication type:

Article

HER3 targeting augments the efficacy of panobinostat in claudin-low triple-negative breast cancer cells.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00422-8

By:

Lyu, Hui;
Hou, Defu;
Liu, Hao;
Ruan, Sanbao;
Tan, Congcong;
Wu, Jiande;
Hicks, Chindo;
Liu, Bolin

Publication type:

Article

Tackling FGFR3-driven bladder cancer with a promising synergistic FGFR/HDAC targeted therapy.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00417-5

By:

Wang, Zechen;
Muthusamy, Viswanathan;
Petrylak, Daniel P.;
Anderson, Karen S.

Publication type:

Article

Behaviour: Epigenetically bonded.

Published in:

Nature Reviews Neuroscience, 2013, v. 14, n. 7, p. 457, doi. 10.1038/nrn3537

By:

Flight, Monica Hoyos

Publication type:

Article

Thyroid Hormone–mediated Histone Modification Protects Cortical Neurons From the Toxic Effects of Hypoxic Injury.

Published in:

Journal of the Endocrine Society, 2022, v. 6, n. 11, p. 1, doi. 10.1210/jendso/bvac139

By:

Abe, Kiyomi;
Li, Jianrong;
Liu, Yan Yun;
Brent, Gregory A

Publication type:

Article

Epigenetic Regulation of HIV-1 Sense and Antisense Transcription in Response to Latency-Reversing Agents.

Published in:

Non-Coding RNA, 2023, v. 9, n. 1, p. 5, doi. 10.3390/ncrna9010005

By:

Li, Rui;
Caico, Isabella;
Xu, Ziyan;
Iqbal, Mohammad Shameel;
Romerio, Fabio

Publication type:

Article

Suppression of IL-12p40-related regulatory cytokines by suberoylanilide hydroxamic acid an inhibitor of histone deacetylases.

Published in:

Immunopharmacology & Immunotoxicology, 2016, v. 38, n. 4, p. 281, doi. 10.1080/08923973.2016.1188940

By:

Dobreva, Zlatka Georgieva;
Grigorov, Boncho Grigorov;
Stanilova, Spaska Angelova

Publication type:

Article

Dual inhibitors of DNMT and HDAC induce viral mimicry to induce antitumour immunity in breast cancer.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01895-7

By:

Huang, Wenjun;
Zhu, Qingyun;
Shi, Zhichao;
Tu, Yao;
Li, Qinyuan;
Zheng, Wenwen;
Yuan, Zigao;
Li, Lulu;
Zu, Xuyu;
Hao, Yue;
Chu, Bizhu;
Jiang, Yuyang

Publication type:

Article

Super-enhancers and the super-enhancer reader BRD4: tumorigenic factors and therapeutic targets.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01775-6

By:

Qian, Haihong;
Zhu, Min;
Tan, Xinyu;
Zhang, Yixing;
Liu, Xiangning;
Yang, Li

Publication type:

Article

Cancer gene therapy: Prospects of using human sodium iodide symporter gene in non-thyroidal cancer.

Published in:

Biomedical Research Journal, 2015, v. 2, n. 2, p. 198

By:

Dutta, Shruti;
De, Abhijit

Publication type:

Article

Human EGFR-2, EGFR and HDAC Triple-Inhibitor CUDC-101 Enhances Radiosensitivity of GBM Cells.

Published in:

Biomedical Research Journal, 2015, v. 2, n. 1, p. 105

By:

Schlaff, Cody D.;
Arscott, W. Tristram;
Gordon, Ira;
Camphausen, Kevin A.;
Tandle, Anita

Publication type:

Article

Unraveling Epigenetic Changes in A. thaliana Calli: Impact of HDAC Inhibitors.

Published in:

Plants (2223-7747), 2023, v. 12, n. 24, p. 4177, doi. 10.3390/plants12244177

By:

Pírek, Pavlína;
Kryštofová, Karolína;
Kováčová, Ingrid;
Kromerová, Anna;
Zachová, Dagmar;
Helia, Ondřej;
Panzarová, Klára;
Fajkus, Jiří;
Zdráhal, Zbyněk;
Lochmanová, Gabriela;
Fojtová, Miloslava

Publication type:

Article

Histone Deacetylase Inhibitors Increase the Embryogenic Potential and Alter the Expression of Embryogenesis-Related and HDAC-Encoding Genes in Grapevine (Vitis vinifera L., cv. Mencía).

Published in:

Plants (2223-7747), 2021, v. 10, n. 6, p. 1164, doi. 10.3390/plants10061164

By:

Martínez, Óscar;
Arjones, Verónica;
González, María Victoria;
Rey, Manuel

Publication type:

Article

Trichostatin A Affects Developmental Reprogramming of Bread Wheat Microspores towards an Embryogenic Route.

Published in:

Plants (2223-7747), 2020, v. 9, n. 11, p. 1442, doi. 10.3390/plants9111442

By:

Castillo, Ana María;
Valero-Rubira, Isabel;
Burrell, María Ángela;
Allué, Sandra;
Costar, María Asunción;
Vallés, María Pilar

Publication type:

Article

A selective histone deacetylase 6 inhibitor showed antiviral activity against dengue and Zika viruses.

Published in:

Journal of Medical Sciences (1011-4564), 2023, v. 43, n. 5, p. 219, doi. 10.4103/jmedsci.jmedsci_212_22

By:

Shih, Hao-Wen;
Tsao, Chang-Huei;
Chang, Yu-Hsiu;
Yang, Chih-Wei;
Feng, Shao-Wei;
Chiu, Kuo-Chou

Publication type:

Article

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment.

Published in:

Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0604-3

By:

Ma, Jiacheng;
Huo, XiaoJiao;
Jarpe, Matthew B.;
Kavelaars, Annemieke;
Heijnen, Cobi J.

Publication type:

Article

Dual targeting of histone deacetylases and MYC as potential treatment strategy for H3-K27M pediatric gliomas.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.96257

By:

Algranati, Danielle;
Oren, Roni;
Dassa, Bareket;
Fellus-Alyagor, Liat;
Plotnikov, Alexander;
Barr, Haim;
Harmelin, Alon;
London, Nir;
Guy Ron;
Furth, Noa;
Shema, Efrat

Publication type:

Article

Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes.

Published in:

Molecular Genetics & Genomic Medicine, 2020, v. 8, n. 10, p. 1, doi. 10.1002/mgg3.1429

By:

Alshawli, Abdulelah S.;
Wurdak, Heiko;
Wood, Ian C.;
Ladbury, John E.

Publication type:

Article

Sodium butyrate and panobinostat induce apoptosis of chronic myeloid leukemia cells via multiple pathways.

Published in:

Molecular Genetics & Genomic Medicine, 2019, v. 7, n. 5, p. N.PAG, doi. 10.1002/mgg3.613

By:

Jia, Xiaoyuan;
Zheng, Yinsuo;
Guo, Yanzi;
Chen, Kan

Publication type:

Article

Impact of latency-reversing agents on human macrophage physiology.

Published in:

Immunity, Inflammation & Disease, 2023, v. 11, n. 1, p. 1, doi. 10.1002/iid3.590

By:

Hany, Laurent;
Turmel, Marc-Olivier;
Barat, Corinne;
Ouellet, Michel;
Tremblay, Michel J.

Publication type:

Article

The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKKα and overcomes gefitinib resistance in non-small cell lung cancer.

Published in:

Cancer Biology & Medicine, 2022, v. 19, n. 8, p. 1173, doi. 10.20892/j.issn.2095-3941.2021.0130

By:

Ting He;
Yinglei Gao;
Yanfen Fang;
Yangming Zhang;
Shuwei Zhang;
Fajun Nan;
Jian Ding;
Yi Chen

Publication type:

Article

The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral T-cell lymphoma: a prospective, multicenter, single arm, phase 1b/2 study.

Published in:

Cancer Biology & Medicine, 2021, v. 18, n. 3, p. 841, doi. 10.20892/j.issn.2095-3941.2020.0413

By:

Wei Zhang;
Liping Su;
Lihong Liu;
Yuhuan Gao;
Quanshun Wang;
Hang Su;
Yuhuan Song;
Huilai Zhang;
Jing Shen;
Hongmei Jing;
Shuye Wang;
Xinan Cen;
Hui Liu;
Aichun Liu;
Zengjun Li;
Jianmin Luo;
Jianxia He;
Jingwen Wang;
O'Connor, O. A.;
Daobin Zhou

Publication type:

Article

Immunosuppressive and metabolic agents that influence allo‐ and xenograft survival by in vivo expansion of T regulatory cells.

Published in:

Xenotransplantation, 2020, v. 27, n. 6, p. 1, doi. 10.1111/xen.12640

By:

Zhao, Yanli;
Hu, Wenjun;
Chen, Pengfei;
Cao, Mengtao;
Zhang, Yingwei;
Zeng, Changchun;
Hara, Hidetaka;
Cooper, David K. C.;
Mou, Lisha;
Luan, Shaodong;
Gao, Hanchao

Publication type:

Article

Wound Healing Effect of HDACi Repositioned Molecules in the Therapy for Chronic Wounds Models.

Published in:

Experimental Dermatology, 2025, v. 34, n. 2, p. 1, doi. 10.1111/exd.70060

By:

Santos‐Mena, Alan;
Gonzalez‐Muñiz, Oscar;
Rodríguez‐Carlos, Adrian;
Guerrero, Alejandro Rivas;
Mendieta, Crisol Rodriguez;
Jacobo Delgado, Yolanda M.;
Muñoz, Gerardo Sauceda;
Rosenstein, Yvonne;
Trujillo‐Paez, Valentin;
Portales‐Perez, Diana;
de Jesus Gonzalez, Luis A.;
Calvillo, Renato;
Gonzalez‐Curiel, Irma;
Vitales‐Noyola, Marlen;
Rivas‐Santiago, Bruno

Publication type:

Article

Vorinostat, a histone deacetylase inhibitor, as a potential novel treatment for psoriasis.

Published in:

Experimental Dermatology, 2022, v. 31, n. 4, p. 567, doi. 10.1111/exd.14502

By:

Samuelov, Liat;
Bochner, Ron;
Magal, Lee;
Malovitski, Kiril;
Sagiv, Nadav;
Nousbeck, Janna;
Keren, Aviad;
Fuchs‐Telem, Dana;
Sarig, Ofer;
Gilhar, Amos;
Sprecher, Eli

Publication type:

Article

Keratinocyte aquaporin‐3 expression induced by histone deacetylase inhibitors is mediated in part by peroxisome proliferator‐activated receptors (PPARs).

Published in:

Experimental Dermatology, 2020, v. 29, n. 4, p. 380, doi. 10.1111/exd.14080

By:

Yang, Rong;
Chowdhury, Shinjini;
Choudhary, Vivek;
Chen, Xunsheng;
Bollag, Wendy B.

Publication type:

Article

Sodium butyrate exerts a neuroprotective effect in rats with acute carbon monoxide poisoning by activating autophagy through the mTOR signaling pathway.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55198-z

By:

Wen, Jing;
Xu, Qiong;
Li, Jing;
Shen, Xuanyang;
Zhou, Xiaolong;
Huang, Jing;
Liu, Shiping

Publication type:

Article

CSE1L is a negative regulator of the RB-DREAM pathway in p53 wild-type NSCLC and can be targeted using an HDAC1/2 inhibitor.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43218-3

By:

Duan, Lei;
Tadi, Mehrdad Jafari;
Maki, Carl G.

Publication type:

Article

CSE1L is a negative regulator of the RB-DREAM pathway in p53 wild-type NSCLC and can be targeted using an HDAC1/2 inhibitor.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43218-3

By:

Duan, Lei;
Tadi, Mehrdad Jafari;
Maki, Carl G.

Publication type:

Article

Histone deacetylase inhibitors inhibit lung adenocarcinoma metastasis via HDAC2/YY1 mediated downregulation of Cdh1.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38848-6

By:

Wang, Dongmei;
Yang, Yixiao;
Cao, Yuxiang;
Meng, Meiyao;
Wang, Xiaobo;
Zhang, Zhengxun;
Fu, Wei;
Duan, Shichao;
Tang, Liming

Publication type:

Article

An antioxidant ameliorates allergic airway inflammation by inhibiting HDAC 1 via HIF-1α/VEGF axis suppression in mice.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-36678-0

By:

Islam, Ramiya;
Dash, D.;
Singh, Rashmi

Publication type:

Article