Works matching DE "HIRUDIN"

Results: 67

New developments in acute anticoagulation therapy: what improvements over traditional heparin are on the horizon?

Published in:

1996

By:

Carter CJ;
Carter, C J

Publication type:

journal article

Robust preparative-scale extracellular production of hirudin in Escherichia coli and its purification and characterization.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2012, v. 39, n. 10, p. 1487, doi. 10.1007/s10295-012-1156-3

By:

Huang, Cuicui;
Zhang, Xuerui;
Qu, Jia;
Zhang, Ping;
Tan, Shuhua

Publication type:

Article

Improving the bioactivity of rHirudin with boronophenylalanine site-specific modification.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 5, p. 3774, doi. 10.3892/mmr.2015.3194

By:

XIUJUAN XIN;
WENSHE LIU;
LIYUN SUN

Publication type:

Article

Time dependent reduction in platelet aggregation using the multiplate analyser and hirudin blood due to platelet clumping.

Published in:

Platelets, 2018, v. 29, n. 3, p. 305, doi. 10.1080/09537104.2017.1384540

By:

Chapman, Kent;
Favaloro, Emmanuel J.

Publication type:

Article

Thrombocytopenia model with minimal manipulation of blood cells allowing whole blood assessment of platelet function.

Published in:

Platelets, 2016, v. 27, n. 4, p. 295, doi. 10.3109/09537104.2015.1095873

By:

Skipper, Mette Tiedemann;
Rubak, Peter;
Larsen, Ole Halfdan;
Hvas, Anne-Mette

Publication type:

Article

Assessment of Multiplate platelet aggregometry using citrate, heparin or hirudin in Rhesus macaques.

Published in:

Platelets, 2015, v. 26, n. 8, p. 730, doi. 10.3109/09537104.2014.988694

By:

Dugan, Greg;
O'Donnell, Lisa;
Hanbury, David B.;
Cline, J. Mark;
Caudell, David L.

Publication type:

Article

Stability of VerifyNow P2Y12 assay results with citrate anticoagulation as compared to hirudin anticoagulation over 20-min period.

Published in:

Platelets, 2015, v. 26, n. 3, p. 271, doi. 10.3109/09537104.2013.867938

By:

Sumaya, Wael;
Joshi, Rajiv R.;
Judge, Heather M.;
Ecob, Rosemary;
Morton, Allison C.;
Storey, Robert F.

Publication type:

Article

Which is the best anticoagulant for whole blood aggregometry platelet function testing? Comparison of six anticoagulants and diverse storage conditions.

Published in:

Platelets, 2012, v. 23, n. 5, p. 359, doi. 10.3109/09537104.2011.624211

By:

Kaiser, Andreas Friedrich Christoph;
Neubauer, Horst;
Franken, Cora Christina;
Krüger, Jan-Christoph;
Mügge, Andreas;
Meves, Saskia Hannah

Publication type:

Article

Effects of hirudin on the expression of basic fibroblast growth factor and transforming growth factor-β<sub>1</sub> in human gingival fibroblasts.

Published in:

West China Journal of Stomatology, 2015, v. 33, n. 1, p. 6, doi. 10.7518/hxkq.2015.01.002

By:

Zheng Yi;
Xuan Kun;
Nan Lan;
Mo Shuixue

Publication type:

Article

Enhanced antithrombotic effect of hirudin by bovine serum albumin nanoparticles.

Published in:

Journal of Experimental Nanoscience, 2016, v. 11, n. 8, p. 619, doi. 10.1080/17458080.2015.1104925

By:

Jing, Fanbo;
Xu, Wen;
Liu, Donghua;
Wang, Chenjing;
Sui, Zhongguo

Publication type:

Article

A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss.

Published in:

BMC Biotechnology, 2018, v. 18, n. 1, p. 1, doi. 10.1186/s12896-018-0431-4

By:

Sheffield, William P.;
Eltringham-Smith, Louise J.;
Bhakta, Varsha

Publication type:

Article

Bivalirudin in percutaneous coronary intervention.

Published in:

2006

By:

Lehman, Sam J.;
Chew, Derek P.

Publication type:

journal article

The effect of recombinant hirudin on rabbit ear flaps with venous insufficiency.

Published in:

Indian Journal of Plastic Surgery, 2014, v. 47, n. 1, p. 102, doi. 10.4103/0970-0358.129633

By:

Duzgun, Serdar;
Nisanci, Mustafa;
Unlu, Erkin

Publication type:

Article

The Effect of Local Application of Natural Hirudin on Random Pattern Skin Flap Microcirculation in a Porcine Model.

Published in:

Cell Biochemistry & Biophysics, 2014, v. 69, n. 3, p. 741, doi. 10.1007/s12013-014-9861-3

By:

Yin, Guo-Qian;
Sun, Zhi-Yong;
Wang, Gang

Publication type:

Article

Hemocompatible polyurethane surfaces.

Published in:

Polymers for Advanced Technologies, 2012, v. 23, n. 11, p. 1500, doi. 10.1002/pat.2072

By:

Wu, Zhaoqiang;
Chen, Hong;
Liu, Xiaoli;
Brash, John L.

Publication type:

Article

Evaluation of anticoagulation with bivalirudin for heparin-induced thrombocytopenia during extracorporeal membrane oxygenation.

Published in:

2022

By:

Hanna, Dylan J;
Torbic, Heather;
Militello, Mike;
Strnad, Kyle;
Krishnan, Sudhir;
Hohlfelder, Ben

Publication type:

journal article

Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0.

Published in:

2021

By:

Fabrizio, Carly;
Levito, Marissa N;
Rivosecchi, Ryan;
Bashline, Michael;
Slocum, Brittany;
Kilic, Arman;
Toma, Catalin;
Murray, Holt;
Ramanan, Raj;
Fowler, Jeffrey;
Hickey, Gavin W;
Horn, Edward T

Publication type:

journal article

Initial conservative management strategy of HeartWare left ventricular assist device thrombosis with intravenous heparin or bivalirudin.

Published in:

2020

By:

Bouzas-Cruz, Noelia;
Gonzalez-Fernandez, Oscar;
Ferrera-Durán, Carlos;
Woods, Andrew;
Robinson-Smith, Nicola;
Tovey, Sian;
Jungschleger, Jérôme;
Booth, Karen;
Shah, Asif;
Parry, Gareth;
MacGowan, Guy A;
Schueler, Stephan

Publication type:

journal article

The effects of a hirudin/liposome complex on a diabetic nephropathy rat model.

Published in:

BMC Complementary & Alternative Medicine, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12906-019-2531-7

By:

Wang, Hongwu;
Cui, Huantian;
Lin, Lan;
Ji, Yue;
Ni, Qing;
Li, Junchen;
Pang, Jianli;
Bing, Gongyan;
Bian, Yuhong

Publication type:

Article

Medical interventions in the management of hamstring muscle injury.

Published in:

European Journal of Sport Science, 2014, v. 14, n. 7, p. 743, doi. 10.1080/17461391.2013.878756

By:

Robinson, Matthew;
Hamilton, Bruce

Publication type:

Article

A Molecular Mechanism Study to Reveal Hirudin's Downregulation to PI3K/AKT Signaling Pathway through Decreasing PDGFRβ in Renal Fibrosis Treatment.

Published in:

BioMed Research International, 2022, p. 1, doi. 10.1155/2022/5481552

By:

Li, Ying;
Zhang, Ling;
Xiong, Weijian;
Gao, Xuan;
Xiong, Yanying;
Sun, Wei

Publication type:

Article

Natural Hirudin Increases Rat Flap Viability by Anti-Inflammation via PARs/p38/NF-κB Pathway.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/597264

By:

Peng, Liu;
Pan, Xinyuan;
Yin, Guoqian

Publication type:

Article

The fraction of recombinant factor VIII:Ag unable to bind von Willebrand factor has no FVIII coagulant activity: studies in vitro.

Published in:

Haemophilia, 2012, v. 18, n. 6, p. 917, doi. 10.1111/j.1365-2516.2012.02861.x

By:

Ofosu, F. A.;
Tse, H.;
Naqvi, A.;
Bhakta, H.;
Song, Y.

Publication type:

Article

In silico designing of a new cysteine analogue of hirudin variant 3 for site specific PEGylation.

Published in:

Research in Pharmaceutical Sciences, 2017, v. 12, n. 1, p. 60, doi. 10.4103/1735-5362.199048

By:

Sajjadi, Seyed Mehdi;
Rahimi, Hamzeh;
Mohammadi, Saeed;
Faranoush, Mohammad;
Mirzahoseini, Hasan;
Toogeh, Gholamreza

Publication type:

Article

Implementation of a Simplistic Bivalirudin-Warfarin Transition Protocol Is Associated With Improved Achievement of INR Values Within the Therapeutic Range.

Published in:

2016

By:

Rollins, Amber R.;
Smith, Kathryn E.;
Zemrak, Wesley R.

Publication type:

journal article

Heparin Versus Bivalirudin Monotherapy in the Setting of Primary Percutaneous Coronary Intervention for Patients With ST-Segment Elevation Myocardial Infarction.

Published in:

2016

By:

Faulkenberg, Kathleen D.;
Beavers, Janna C.;
Finks, Shannon W.

Publication type:

journal article

Structural and Dynamic Insight into Hirudin Epitopes-HLADRB1 0101 Complexes and their Modified Peptide Ligands: A Molecular Dynamic Simulation Study.

Published in:

Tropical Journal of Pharmaceutical Research, 2015, v. 14, n. 12, p. 2171, doi. 10.4314/tjpr.v14i12.3

By:

Asgari, Saeme;
Mirzahoseini, Hasan;
Karimipour, Morteza;
Ebrahim-Habibi, Azadeh

Publication type:

Article

Antithrombotic treatment during coronary angioplasty after failed thrombolysis: strategies and prognostic implications. Results of the RESPIRE registry.

Published in:

2017

By:

De la Torre Hernández, José M.;
Sagredo, Mario Sadaba;
Arrieta, Miren Telleria;
de Carlos, Federico Gimeno;
Sanchez Lacuesta, Elena;
Bullones Ramírez, Juan A.;
Rocamora, Javier Pineda;
Yuste, Victoria Martin;
Garcia Camarero, Tamara;
Larman, Mariano;
Rumoroso, Jose R.;
Sadaba Sagredo, Mario;
Telleria Arrieta, Miren;
Gimeno de Carlos, Federico;
Pineda Rocamora, Javier;
Martin Yuste, Victoria

Publication type:

journal article

Safety of the primary percutaneous coronary intervention strategy combining pre-hospital prasugrel, enoxaparin and in-hospital bivalirudin in acute ST-segment elevation myocardial infarction.

Published in:

2016

By:

Viikilä, Juho;
Nieminen, Tuomo;
Tierala, Ilkka;
Laine, Mika

Publication type:

journal article

More than just one: multiplicity of Hirudins and Hirudin-like Factors in the Medicinal Leech, Hirudo medicinalis.

Published in:

Molecular Genetics & Genomics, 2016, v. 291, n. 1, p. 227, doi. 10.1007/s00438-015-1100-0

By:

Müller, Christian;
Mescke, Katharina;
Liebig, Stephanie;
Mahfoud, Hala;
Lemke, Sarah;
Hildebrandt, Jan-Peter

Publication type:

Article

Diselenide crosslinks for enhanced and simplified oxidative protein folding.

Published in:

Communications Chemistry, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42004-021-00463-9

By:

Mousa, Reem;
Hidmi, Taghreed;
Pomyalov, Sergei;
Lansky, Shifra;
Khouri, Lareen;
Shalev, Deborah E.;
Shoham, Gil;
Metanis, Norman

Publication type:

Article

Monitoring the Direct Thrombin Inhibitors.

Published in:

Clinical Laboratory Science, 2013, v. 26, n. 1, p. 54, doi. 10.29074/ascls.26.1.54

By:

FRITSMA, GEORGE A.

Publication type:

Article

p38/TF/HIF-α Signaling Pathway Participates in the Progression of CIPN in Mice.

Published in:

BioMed Research International, 2019, p. 1, doi. 10.1155/2019/5347804

By:

Yang, Yang;
Hu, Liang;
Wang, Chaoyu;
Yang, Xing;
Song, Ling;
Jiang, Chunyi;
Li, Yan;
Li, Tianxi;
Liu, Wen-Tao;
Feng, Jifeng

Publication type:

Article

Therapeutic Potentials of Medicinal Leech in Chinese Medicine.

Published in:

American Journal of Chinese Medicine, 2024, v. 52, n. 4, p. 1027, doi. 10.1142/S0192415X24500423

By:

Wu, Shaohua;
Zhou, Yaya;
Wang, Yang;
Zhang, Zuping

Publication type:

Article

Safety, Pharmacokinetics and Pharmacodynamics of TNHH, a Novel Targeted Neutrophil-Inhibitory Hirulog Hybrid Glycoprotein, in Healthy Volunteers.

Published in:

2019

By:

Gou, Zhong Ping;
Song, Zi Hui;
Chen, Xiao Gang;
Hu, Xiao Cheng;
Wang, Ying;
Fan, Kai;
Cai, Yong Ming;
Zheng, Li

Publication type:

journal article

Hirudin elimination by hemofiltration: A comparative in vitro study of different membranes.

Published in:

Kidney International, 1999, v. 56, p. S41, doi. 10.1046/j.1523-1755.56.s72.3.x

By:

Frank, Rolf D.;
Farber, Heiko;
Stefanidis, Ioannis;
Lanzmich, Regina;
Kierdorf, Horst P.

Publication type:

Article

Recombinant hirudin (lepirudin) as anticoagulant in intensive care patients treated with continuous hemodialysis.

Published in:

Kidney International, 1999, v. 56, p. S46, doi. 10.1046/j.1523-1755.56.s72.2.x

By:

Fischer, Karl-Georg;
van de Loo, Andreas;
Böhler, Joachim

Publication type:

Article

Direct thrombin inhibition during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.

Published in:

2007

By:

Lewis, Bruce E.;
Hursting, Marcie J.

Publication type:

journal article

Structural basis of RGD-hirudin binding to thrombin: Tyr<sub>3</sub> and five C-terminal residues are crucial for inhibiting thrombin activity.

Published in:

BMC Structural Biology, 2014, v. 14, p. 50, doi. 10.1186/s12900-014-0026-9

By:

Yinong Huang;
Yanling Zhang;
Bing Zhao;
Qiping Xu;
Xiushi Zhou;
Houyan Song;
Min Yu;
Wei Mo

Publication type:

Article

Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition.

Published in:

BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-31

By:

Roddick, Leigh Ann;
Bhakta, Varsha;
Sheffield, William P.

Publication type:

Article

Bivalirudin versus heparin and provisional GP IIb/IIIa inhibitors in patients treated for ST-segment elevation myocardial infarctions: Comparison of outcomes in a "real-world" setting.

Published in:

2017

By:

Fach, Andreas;
Backhaus, Tina;
Schmucker, Johannes;
Zabrocki, Robert;
Garstka, Daniela;
Stehmeier, Janina;
Fiehn, Eduard;
Hambrecht, Rainer;
Wienbergen, Harm

Publication type:

journal article

A Comparative Study of Bivalirudin Plus Clopidogrel versus Bivalirudin Plus Prasugrel in Primary Angioplasty Using Propensity Score Matching.

Published in:

Journal of Interventional Cardiology, 2013, v. 26, n. 5, p. 463, doi. 10.1111/joic.12058

By:

DÍAZ DE LA LLERA, LUIS S.;
CUBERO GÓMEZ, JOSÉ‐M.;
RANGEL, DIEGO;
PAREJO, JUAN;
ACOSTA, JUAN;
FERNÁNDEZ‐CISNAL, AGUSTÍN;
ZAFRA, FRANCISCO;
BENEZET, JAVIER

Publication type:

Article

Total Synthesis of Homogeneous Variants of Hirudin P6: A Post-Translationally Modified Anti-Thrombotic Leech-Derived Protein.

Published in:

Angewandte Chemie, 2014, v. 126, n. 15, p. 4028, doi. 10.1002/ange.201310777

By:

Hsieh, Yves S. Y.;
Wijeyewickrema, Lakshmi C.;
Wilkinson, Brendan L.;
Pike, Robert N.;
Payne, Richard J.

Publication type:

Article

Hirudins and hirudin-like factors in Hirudinidae: implications for function and phylogenetic relationships.

Published in:

Parasitology Research, 2017, v. 116, n. 1, p. 313, doi. 10.1007/s00436-016-5294-9

By:

Müller, Christian;
Lemke, Sarah;
Hildebrandt, Jan-Peter;
Haase, Martin

Publication type:

Article

A water‐soluble selenoxide reagent as a useful probe for the reactivity and folding of polythiol peptides.

Published in:

FEBS Open Bio, 2013, v. 3, n. 1, p. 55, doi. 10.1016/j.fob.2012.12.004

By:

Arai, Kenta;
Noguchi, Masato;
Singh, Beena G.;
Priyadarsini, K. Indira;
Fujio, Katsuhiko;
Kubo, Yurika;
Takayama, Kyoko;
Ando, Setsuko;
Iwaoka, Michio

Publication type:

Article

Anticoagulation in patients with acute kidney injury undergoing kidney replacement therapy.

Published in:

Pediatric Nephrology, 2022, v. 37, n. 10, p. 2303, doi. 10.1007/s00467-021-05020-z

By:

Raina, Rupesh;
Chakraborty, Ronith;
Davenport, Andrew;
Brophy, Patrick;
Sethi, Sidharth;
McCulloch, Mignon;
Bunchman, Timothy;
Yap, Hui Kim

Publication type:

Article

The Acquisition of Complement-Dependent Cytotoxicity by the Type II Anti-CD20 Therapeutic Antibody Obinutuzumab.

Published in:

Cancers, 2024, v. 16, n. 1, p. 49, doi. 10.3390/cancers16010049

By:

Kuźniewska, Alicja;
Majeranowski, Alan;
Henry, Sara;
Kowalska, Daria;
Stasiłojć, Grzegorz;
Urban, Aleksandra;
Zaucha, Jan M.;
Okrój, Marcin

Publication type:

Article

Go West: Hirudins and Decorsin/Ornatin-like Platelet Aggregation Inhibitors in Two Representatives of American Hematophagous Leeches.

Published in:

Parasitologia, 2022, v. 2, n. 4, p. 313, doi. 10.3390/parasitologia2040026

By:

Pfordt, Victoria;
Kalatehjari, Pegah;
Tolksdorf, Céline;
Rauch, Bernhard H.;
Müller, Christian

Publication type:

Article

A systematic review on the use of new anticoagulants in pregnancy.

Published in:

Obstetric Medicine (1753-495X), 2013, v. 6, n. 2, p. 64, doi. 10.1177/1753495X12472642

By:

Ai-Wei Tang;
Greer, Ian

Publication type:

Article

Critical Appraisal of Bivalirudin versus Heparin for Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Trials.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0127832

By:

Bavry, Anthony A.;
Elgendy, Islam Y.;
Mahmoud, Ahmed;
Jadhav, Manoj P.;
Huo, Tianyao

Publication type:

Article