Works about HIPPO signaling pathway

Results: 761

The emerging roles of YAP/TAZ in melanoma: A scoping review of the currently available evidence.

Published in:

World Academy of Sciences Journal, 2025, v. 7, n. 4, p. 1, doi. 10.3892/wasj.2025.356

By:

WARDHANI, SAVITRI RESTU;
BUSTAMAN, ANDREW LAURIE;
SOETADJI, RAY SEBASTIAN;
SANJAYA, ARDO

Publication type:

Article

XMU-MP-1, Inhibitor of STE20-like MST1/2 Kinases of the Hippo Signaling Pathway, Suppresses the Cell Cycle, Activates Apoptosis and Autophagy, and Induces Death of Hematopoietic Tumor Cells.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 874, doi. 10.3390/ph18060874

By:

Stepchenko, Alexander G.;
Georgieva, Sofia G.;
Pankratova, Elizaveta V.

Publication type:

Article

CRISPR-cas9 screening identified lethal genes enriched in Hippo kinase pathway and of predictive significance in primary low-grade glioma.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00652-3

By:

Mijiti, Maimaitili;
Maimaiti, Aierpati;
Chen, Xiaoqing;
Tuersun, Maidina;
Dilixiati, Miershayiti;
Dilixiati, Yilidanna;
Zhu, Guohua;
Wu, Hao;
Li, Yandong;
Turhon, Mirzat;
Abulaiti, Aimitaji;
Maimaitiaili, Nuerailijiang;
Yiming, Nadire;
Kasimu, Maimaitijiang;
Wang, Yongxin

Publication type:

Article

Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00649-y

By:

Li, Yunchao;
Wang, Xiaoxiao;
Pan, Changyu;
Yuan, Hui;
Li, Xinyi;
Chen, Zejun;
He, Haoyu

Publication type:

Article

Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00613-w

By:

Ko, Hung-Shuo;
Laiman, Vincent;
Tsao, Po-Nien;
Chen, Chung-Ming;
Chuang, Hsiao-Chi

Publication type:

Article

NDR1 increases NOTCH1 signaling activity by impairing Fbw7 mediated NICD degradation to enhance breast cancer stem cell properties.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00480-x

By:

Wang, Ling-Ling;
Wan, Xiao-Yun;
Liu, Chun-Qi;
Zheng, Fei-Meng

Publication type:

Article

Generation of Vgll4‐DreER transgenic mouse for visualizing and manipulating VGLL4‐expressing cells in vivo.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 10, p. 1, doi. 10.1002/jbt.23435

By:

Zhong, Yazhu;
Tan, Xixi;
Wang, Xiaodong;
Jiang, Jun;
Song, Kai;
Chen, Haiyuan;
Zhang, Hao;
Wang, Zuoyun;
Zhang, Lei;
Guo, Chunming;
Liang, Hongfeng;
Yu, Wei

Publication type:

Article

Natural compound library screening to identify berberine as a treatment for rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 3, p. 959, doi. 10.1007/s10067-024-06871-1

By:

Zhang, Li;
Tan, Min;
Mao, Jing;
Zhang, Juan;
Wang, Xiao-Yuan;
Zhang, Yan;
Duo, Rui-Xue;
Hao, Jia-Yao;
Shen, Hai-Li

Publication type:

Article

Yes-associated protein is dysregulated during nitrofen-induced hypoplastic lung development due to congenital diaphragmatic hernia.

Published in:

Pediatric Surgery International, 2022, v. 38, n. 5, p. 713, doi. 10.1007/s00383-022-05099-x

By:

Kahnamoui, Shana;
Khoshgoo, Naghmeh;
Patel, Daywin;
Wagner, Richard;
Keijzer, Richard

Publication type:

Article

Relationship between Stemness, Reactive Oxygen Species, and Epithelial-to-Mesenchymal Transition in Model Circulating Tumor Cells.

Published in:

Cells Tissues Organs, 2022, v. 211, n. 3, p. 282, doi. 10.1159/000516574

By:

Brown, Spenser R.;
Bates, Juliana C.;
Avera, Alexandra D.;
Kim, Yonghyun

Publication type:

Article

FAM64A silencing inhibits the proliferation, migration, invasion, and epithelial-mesenchymal transition in ovarian cancer cells via activating Hippo pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02710-0

By:

Luo, Jianxiu;
Li, Ruiyang

Publication type:

Article

Loss of Mst1/2 activity promotes non-mitotic hair cell generation in the neonatal organ of Corti.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00261-4

By:

Lu, Xiaoling;
Yu, Huiqian;
Ma, Jiaoyao;
Wang, Kunkun;
Guo, Luo;
Zhang, Yanping;
Li, Boan;
Zhao, Zehang;
Li, Huawei;
Sun, Shan

Publication type:

Article

Hippo-Yap/Taz signalling in zebrafish regeneration.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00209-8

By:

Riley, Susanna E.;
Feng, Yi;
Hansen, Carsten Gram

Publication type:

Article

Hippo pathway in cancer cells induces NCAM1+αSMA+ fibroblasts to modulate tumor microenvironment.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07041-4

By:

Thinyakul, Chanida;
Sakamoto, Yasuhisa;
Shimoda, Mayuko;
Liu, Yanliang;
Thongchot, Suyanee;
Reda, Omnia;
Nita, Akihiro;
Sakamula, Romgase;
Sampattavanich, Somponnat;
Maeda, Ayato;
Chunthaboon, Paweenapon;
Nduru, David;
Niimura, Mayumi;
Kanamori, Yohei;
Thuwajit, Peti;
Nakayama, Keiichi I.;
Guan, Kun-Liang;
Satou, Yorifumi;
Thuwajit, Chanitra;
Moroishi, Toshiro

Publication type:

Article

Antitumor activity of gilteritinib, an inhibitor of AXL, in human solid tumors.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02417-9

By:

Zhang, Zuxiong;
Hu, Ruxia;
Liu, Jie;
Yang, Xiaohan;
Xiao, Youban;
Xu, Xi;
Liu, Xinxin;
Zeng, Wen;
Zhang, Shuyong;
Wang, Liefeng

Publication type:

Article

Antitumor activity of gilteritinib, an inhibitor of AXL, in human solid tumors.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02417-9

By:

Zhang, Zuxiong;
Hu, Ruxia;
Liu, Jie;
Yang, Xiaohan;
Xiao, Youban;
Xu, Xi;
Liu, Xinxin;
Zeng, Wen;
Zhang, Shuyong;
Wang, Liefeng

Publication type:

Article

YAP/TAZ-Hippo pathway mediates the tumorigenesis of various cancers through post-translational modification represented by ubiquitination.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02319-w

By:

Xu, Fangshi;
Li, Zongyu;
Guan, Hao;
Ma, Jiancang

Publication type:

Article

Regulatory roles of RNA binding proteins in the Hippo pathway.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02316-z

By:

Peng, Shuchang;
Li, Chenglin;
He, Yanwen;
Xue, Lei;
Guo, Xiaowei

Publication type:

Article

The long noncoding RNA ELFN1-AS1 promotes gastric cancer growth and metastasis by interacting with TAOK1 to inhibit the Hippo signaling pathway.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02235-5

By:

Wang, Yuanhang;
Shen, Kuan;
Cheng, Quan;
Zhou, Xinyi;
Liu, Kanghui;
Xiao, Jian;
Hu, Li

Publication type:

Article

Regulation of Hippo/YAP axis in colon cancer progression by the deubiquitinase JOSD1.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02136-7

By:

Sun, Yanan;
Liu, Dongyi;
Zhang, Xiaobo;
Su, Peng;
Li, Xin;
Li, Zhongbo;
Gai, Yingwen;
Li, Jingying;
Yang, Zhiyong;
Ding, Yinlu;
Zhu, Jian;
Tan, Xiaodong

Publication type:

Article

Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01839-1

By:

Seeneevassen, Lornella;
Zaafour, Anissa;
Sifré, Elodie;
Genevois, Coralie;
Nguyen, Tra Ly;
Pobiedonoscew, Yasmine;
Giese, Alban;
Guignard, Jérôme;
Tiffon, Camille;
Rousseau, Benoit;
Raymond, Anne-Aurélie;
Belleannée, Geneviève;
Boeuf, Hélène;
Gronnier, Caroline;
Martin, Océane C. B.;
Giraud, Julie;
Lehours, Philippe;
Dubus, Pierre;
Varon, Christine

Publication type:

Article

Role of PATJ in stroke prognosis by modulating endothelial to mesenchymal transition through the Hippo/Notch/PI3K axis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01857-z

By:

Medina-Dols, Aina;
Cañellas, Guillem;
Capó, Toni;
Solé, Montse;
Mola-Caminal, Marina;
Cullell, Natalia;
Jaume, Marina;
Nadal-Salas, Laura;
Llinàs, Jaume;
Gómez, Lluis;
Tur, Silvia;
Jiménez, Carmen;
Díaz, Rosa M.;
Carrera, Caty;
Muiño, Elena;
Gallego-Fabrega, Cristina;
Soriano-Tárraga, Carolina;
Ruiz-Guerra, Laura;
Pol-Fuster, Josep;
Asensio, Víctor

Publication type:

Article

Molecular Mechanism of Curcumin Derivative on YAP Pathway against Ovarian Cancer.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 23, p. 7220, doi. 10.3390/jcm11237220

By:

Zheng, Nan;
Liu, Shan;
Zeng, Huiting;
Zhao, Huajun;
Jin, Lixu

Publication type:

Article

The Effect of Stimulation Protocols (GnRH Agonist vs. Antagonist) on the Activity of mTOR and Hippo Pathways of Ovarian Granulosa Cells and Its Potential Correlation with the Outcomes of In Vitro Fertilization: A Hypothesis.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 20, p. 6131, doi. 10.3390/jcm11206131

By:

Papapanou, Michail;
Syristatidi, Kalliopi;
Gazouli, Maria;
Eleftheriades, Makarios;
Vlahos, Nikolaos;
Siristatidis, Charalampos

Publication type:

Article

SU4312 Represses Glioma Progression by Inhibiting YAP and Inducing Sensitization to the Effect of Temozolomide.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 16, p. 4765, doi. 10.3390/jcm11164765

By:

Wang, Xu;
Zhou, Yi;
Wang, Yan;
Wang, Xiang;
Zhang, Yu;
Mao, Yufei;
Zhang, Long;
Qi, Ji;
Zhang, Yining;
Lyu, Feng;
Gu, Linbo;
Yu, Rutong;
Zhou, Xiuping

Publication type:

Article

连翘苷通过激活Hippo-YAP信号通路抑制结肠癌LS180 细胞的恶性生物学行为.

Published in:

Chinese Journal of Cancer Biotherapy, 2024, v. 31, n. 6, p. 566, doi. 10.3872/j.issn.1007-385x.2024.06.004

By:

郑成富;
周贵丰;
李青;
陈营

Publication type:

Article

虎杖苷通过Hippo/YAP通路影响甲状腺癌8505C细胞的恶性生物学行为和顺铂敏感性.

Published in:

Chinese Journal of Cancer Biotherapy, 2024, v. 31, n. 3, p. 224, doi. 10.3872/j.issn.1007-385x.2024.03.003

By:

曹建中;
黄金石;
丁亚亭

Publication type:

Article

Hippo-YAP/TAZ信号通路调控铁死亡对肿瘤影响的研究进展.

Published in:

Chinese Journal of Cancer Biotherapy, 2023, v. 30, n. 10, p. 919, doi. 10.3872/j.issn.1007-385x.2023.10.011

By:

刘靖芳

Publication type:

Article

Follicle Stimulating Hormone stimulation causes divergent response in Granulosa cell gene expression in typical and non-cycling heifers.

Published in:

Journal of Animal Science, 2025, v. 103, p. 24, doi. 10.1093/jas/skaf102.027

By:

Rudloff, Brooke;
Stohlmann, Mackenzie;
Reith, Rachel;
Nafziger, Sarah;
Abedal-Majed, Mohamed;
Keane, Jessica;
Kurz, Scott;
Wood, Jennifer;
Cupp, Andrea S.

Publication type:

Article

Influence of early maternal gestational body weight gain on liver gene expression across generations in offspring.

Published in:

2024

By:

Ramirez-zamudio, German D.;
Dahlen, Carl R.;
Baumgaertner, Friederike;
Menezes, Ana Clara B.;
Hurlbert, Jennifer L.;
Bochantin-Winders, Kerri A.;
Underdahl, Sarah R. R.;
McCarthy, Kacie L.;
Reynolds, Lawrence P. P.;
Ward, Alison K.;
Borowicz, Pawel P. P.;
Sedivec, Kevin K.;
Caton, Joel S. S.;
Da Silva Diniz, Wellison Jarles

Publication type:

Abstract

A role for miRNAs in the regulation of brown adipose tissue whitening in goats (Capra Hircus).

Published in:

Journal of Animal Science, 2024, v. 102, p. 1, doi. 10.1093/jas/skae124

By:

Zhao, Le;
Li, Minhao;
Xiao, Min;
Chen, Meixi;
Yang, Haili;
Zhao, Yongju

Publication type:

Article

Mechanical Properties of Glioblastoma: Perspectives for YAP/TAZ Signaling Pathway and Beyond.

Published in:

Diseases, 2023, v. 11, n. 2, p. 86, doi. 10.3390/diseases11020086

By:

Pontes, Bruno;
Mendes, Fabio A.

Publication type:

Article

Cross-Oxygen Gradients Transcriptomic Comparison Revealed the Central Role of MAPK and Hippo in Hypoxia-Mediated Mammary Proliferation Inhibition.

Published in:

Antioxidants, 2024, v. 13, n. 3, p. 288, doi. 10.3390/antiox13030288

By:

Hu, Zhenzhen;
Lu, Yi;
Cai, Jie;
Liu, Jianxin;
Wang, Diming

Publication type:

Article

Cardioprotective Effects of Dexmedetomidine in an Oxidative-Stress In Vitro Model of Neonatal Rat Cardiomyocytes.

Published in:

Antioxidants, 2023, v. 12, n. 6, p. 1206, doi. 10.3390/antiox12061206

By:

Borger, Moritz;
von Haefen, Clarissa;
Bührer, Christoph;
Endesfelder, Stefanie

Publication type:

Article

Bone marrow mesenchymal stem cells-derived exosomal lncRNA GAS5 mitigates heart failure by inhibiting UL3/Hippo pathway-mediated ferroptosis.

Published in:

European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-024-01880-x

By:

Ren, Yu;
Zhao, Xingsheng

Publication type:

Article

Novel KDM2B/SAV1 Signaling Pathway Promotes the Progression of Gastric Cancer.

Published in:

Genetics Research, 2023, v. 2023, p. 1, doi. 10.1155/2023/1230182

By:

Li, Ning;
Song, Haifei;
Chen, Zhiqin;
Chen, Chen;
Quan, Ming

Publication type:

Article

Hippo pathway-mediated YAP1/ TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.84532

By:

Yifan Wu;
Kunhua Qin;
Yi Xu;
Rajhans, Shreya;
Vo, Truong;
Lopez, Kevin M;
Jun Liu;
Nipper, Michael H;
Deng, Janice;
Xue Yin;
Ramjit, Logan R;
Zhenqing Ye;
Yu Luan;
Arda, H. Efsun;
Pei Wang

Publication type:

Article

The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.90818

By:

Phillips, Jonathan E.;
Duojia Pan

Publication type:

Article

TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.87394

By:

Grove, Matthew;
Hyukmin Kim;
Shuhuan Pang;
Amaya, Jose Paz;
Guoqing Hu;
Jiliang Zhou;
Lemay, Michel;
Young-Jin Son

Publication type:

Article

Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.88508

By:

Bulos, Maya L.;
Grzelak, Edyta M.;
Li-Ma, Chloris;
Chen, Emily;
Hull, Mitchell;
Johnson, Kristen A.;
Bollong, Michael J.

Publication type:

Article

Competition between myosin II and βH-spectrin regulates cytoskeletal tension.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84918

By:

Ibar, Consuelo;
Chinthalapudi, Krishna;
Heissler, Sarah M.;
Irvine, Kenneth D.

Publication type:

Article

Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85092

By:

Warren, Rachel;
Handeng Lyu;
Klinkhammer, Kylie;
De Langhe, Stijn P.

Publication type:

Article

Arsenic impairs stem cell differentiation via the Hippo signaling pathway.

Published in:

Toxicology Research, 2023, v. 12, n. 2, p. 296, doi. 10.1093/toxres/tfad018

By:

Perego, M Chiara;
McMichael, Benjamin D;
Bain, Lisa J

Publication type:

Article

Circular RNA expression profiles in human bronchial epithelial cells treated with beryllium sulfate.

Published in:

Toxicology Research, 2021, v. 10, n. 5, p. 1013, doi. 10.1093/toxres/tfab086

By:

Liu, Yan-ping;
Cai, Ying;
Lei, Yuan-di;
Yuan, Xiao-yan;
Wang, Ye;
Yi, Shan;
Li, Xun-ya;
Huang, Lian;
Long, Ding-xin;
Zhang, Zhao-hui

Publication type:

Article

Enhanced osteogenic and angiogenic capabilities of adipose-derived stem cells in fish collagen scaffolds for treatment of femoral head osteonecrosis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03015-6

By:

Zheng, Pinxuan;
Jia, Qi;
Li, Zhongzhe;
Jiang, Heng Bo;
Zhou, Lu

Publication type:

Article

Down-regulation of YAP prevents smoking- and alcohol-induced carcinogenesis of esophageal paracancerous tissue by promoting cellular pyroptosis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98952-7

By:

Ding, Xinyu;
Li, Ying;
Wang, Xuning;
Li, Fan;
Xu, Zhifei;
Zhu, Yongfei;
Chen, Zihao

Publication type:

Article

Ferulic acid lipid nano capsules versus its native form in alleviating diabetic nephropathy induced in rats through TGF-β1/Hippo pathway crosstalk modulation.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-024-81175-7

By:

Zohny, Mona H.;
El-Far, Yousra M.;
Kabil, Mohamed Fawzi;
El-Swefy, Sahar E.;
El-Sherbiny, Ibrahim M.;
El-Shishtawy, Mamdouh M.

Publication type:

Article

Uncovering Hippo pathway-related biomarkers in acute myocardial infarction via scRNA-seq binding transcriptomics.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-94820-6

By:

Li, Xingda;
He, Xueqi;
Zhang, Yu;
Hao, Xinyuan;
Xiong, Anqi;
Huang, Jiayu;
Jiang, Biying;
Tong, Zaiyu;
Huang, Haiyan;
Yi, Lian;
Chen, Wenjia

Publication type:

Article

Uncovering Hippo pathway-related biomarkers in acute myocardial infarction via scRNA-seq binding transcriptomics.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-94820-6

By:

Li, Xingda;
He, Xueqi;
Zhang, Yu;
Hao, Xinyuan;
Xiong, Anqi;
Huang, Jiayu;
Jiang, Biying;
Tong, Zaiyu;
Huang, Haiyan;
Yi, Lian;
Chen, Wenjia

Publication type:

Article

Lats-IN-1 protects cardiac function and promotes regeneration after myocardial infarction by targeting the hippo pathway.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1463465

By:

Shen, Hua;
Wang, Qing;
Liu, Bohan;
Wang, Yihui;
Zhou, Dandan;
Zhang, Lin;
Zhuang, Jinqiang

Publication type:

Article