Works matching DE "HEPARANASE"

Results: 255

Is expression of rat breast matrix components influenced by estrogen, progestins and tibolone?

Published in:

Climacteric, 2015, v. 18, n. 4, p. 523, doi. 10.3109/13697137.2015.1007122

By:

Cunha, E. P.;
Pompei, L. M.;
Theodoro, T. R.;
Steiner, M. L.;
Silva, V. F.;
Silveira, E. R. A.;
Mader, A. M. A. A.;
Pinhal, M. A. S.;
Fernandes, C. E.

Publication type:

Article

Heparanase tailors syndecan for exosome production.

Published in:

2016

By:

David, Guido;
Zimmermann, Pascale

Publication type:

Opinion

Oral Session 28 (Imperial Ballroom): Cancer: resistance and metastasis.

Published in:: 2013
Publication type:: Abstract

The modulation of endothelial glycocalyx by sulodexide on the porcine model of enzymatic endothelial glycocalyx damage – a pilot study.

Published in:

Clinical Hemorheology & Microcirculation, 2025, v. 89, n. 2, p. 181, doi. 10.1177/13860291241305514

By:

Astapenko, David;
Gorskaja, Diana;
Zrzavecky, Marek;
Kawashima, Hanako;
Ssali, Edward;
Navratil, Pavel;
Hana, Ludek;
Motesicky, Jan;
Radochova, Vera;
Hyspler, Radomir;
Ticha, Alena;
Lehmann, Christian;
Malbrain, Manu LNG;
Zadak, Zdenek;
Cerny, Vladimir

Publication type:

Article

A porcine model of endothelial glycocalyx damage by enzymatic digestion: A pilot study.

Published in:

Clinical Hemorheology & Microcirculation, 2021, v. 78, n. 3, p. 325, doi. 10.3233/CH-211133

By:

Astapenko, David;
Ticha, Alena;
Hyspler, Radomir;
Tomasova, Adela;
Navratil, Pavel;
Maly, Ondrej;
Parizkova, Renata Cerna;
Cizkova, Dana;
Huey, Shin Chua;
Lehmann, Christian;
Malbrain, Manu L.N.G.;
Cerny, Vladimir

Publication type:

Article

Role of heparanase in pulmonary hypertension.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1202676

By:

Lin-Jun Wang;
Fei Feng;
Jian-Chun Li;
Ting-Ting Chen;
Li-Ping Liu

Publication type:

Article

Role of heparanase in ARDS through autophagy and exosome pathway (review).

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1200782

By:

Fei Feng;
Lin-Jun Wang;
Jian-Chun Li;
Ting-Ting Chen;
Liping Liu

Publication type:

Article

Nuclear heparanase-1 activity suppresses melanoma progression via its DNA-binding affinity.

Published in:

Oncogene, 2015, v. 34, n. 47, p. 5832, doi. 10.1038/onc.2015.40

By:

Yang, Y;
Gorzelanny, C;
Bauer, A T;
Halter, N;
Komljenovic, D;
Bäuerle, T;
Borsig, L;
Roblek, M;
Schneider, S W

Publication type:

Article

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45012-9

By:

Martinez, Hunter A.;
Koliesnik, Ievgen;
Kaber, Gernot;
Reid, Jacqueline K.;
Nagy, Nadine;
Barlow, Graham;
Falk, Ben A.;
Medina, Carlos O.;
Hargil, Aviv;
Zihsler, Svenja;
Vlodavsky, Israel;
Li, Jin-Ping;
Pérez-Cruz, Magdiel;
Tang, Sai-Wen;
Meyer, Everett H.;
Wrenshall, Lucile E.;
Lord, James D.;
Garcia, K. Christopher;
Palmer, Theo D.;
Steinman, Lawrence

Publication type:

Article

The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes.

Published in:

Transcription (2154-1264), 2012, v. 3, n. 3, p. 130, doi. 10.4161/trns.19998

By:

Yi Qing He;
Sutclife, Elissa L.;
Bunting, Karen L.;
Li, Jasmine;
Goodall, Katharine J.;
Poon, Ivan K. A.;
Hulett, Mark D.;
Freeman, Craig;
Zafar, Anjum;
McInnes, Russell L.;
Taya, Toshiki;
Parish, Christopher R.;
Rao, Sudha

Publication type:

Article

A new role for heparanase in regulating transcription.

Published in:: Nucleus (1949-1034), 2012, v. 3, n. 4, p. 313
Publication type:: Article

Recent data concerning heparanase: focus on fibrosis, inflammation and cancer.

Published in:

Biomolecular Concepts, 2015, v. 6, n. 5/6, p. 415, doi. 10.1515/bmc-2015-0021

By:

Secchi, Maria Francesca;
Masola, Valentina;
Zaza, Gianluigi;
Lupo, Antonio;
Gambaro, Giovanni;
Onisto, Maurizio

Publication type:

Article

The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer.

Published in:

Breast Cancer Research, 2024, v. 26, n. 1, p. 1, doi. 10.1186/s13058-024-01906-6

By:

Manouchehri, Jasmine M.;
Datta, Jharna;
Marcho, Lynn M.;
Reardon, Jesse J.;
Stover, Daniel;
Wesolowski, Robert;
Borate, Uma;
Cheng, Ting-Yuan David;
Schnell, Patrick M.;
Ramaswamy, Bhuvaneswari;
Sizemore, Gina M.;
Rubinstein, Mark P.;
Cherian, Mathew A.

Publication type:

Article

Invasion and metastasis of renal cell carcinoma.

Published in:

Medical Molecular Morphology, 2014, v. 47, n. 2, p. 63, doi. 10.1007/s00795-013-0064-6

By:

Mikami, Shuji;
Oya, Mototsugu;
Mizuno, Ryuichi;
Kosaka, Takeo;
Katsube, Ken-ichi;
Okada, Yasunori

Publication type:

Article

Histone H4 induces heparan sulfate degradation by activating heparanase in chlorine gas-induced acute respiratory distress syndrome.

Published in:

2022

By:

Zhang, Yanlin;
Xu, Fei;
Guan, Li;
Chen, Ming;
Zhao, Yiran;
Guo, Lixia;
Li, Xiao;
Zheng, Yimu;
Gao, Ai;
Li, Shuqiang

Publication type:

journal article

A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition.

Published in:

Journal of Translational Medicine, 2012, v. 10, n. 1, p. 1, doi. 10.1186/1479-5876-10-213

By:

Masola, Valentina;
Onisto, Maurizio;
Zaza, Gianluigi;
Lupo, Antonio;
Gambaro, Giovanni

Publication type:

Article

Heparanase activates the syndecan-syntenin-ALIX exosome pathway.

Published in:

Cell Research, 2015, v. 25, n. 4, p. 412, doi. 10.1038/cr.2015.29

By:

Roucourt, Bart;
Meeussen, Sofie;
Bao, Jie;
Zimmermann, Pascale;
David, Guido

Publication type:

Article

Gene silencing of heparanase results in suppression of invasion and migration of gallbladder carcinoma cells.

Published in:

Bioscience, Biotechnology & Biochemistry, 2018, v. 82, n. 7, p. 1116, doi. 10.1080/09168451.2018.1456316

By:

Jin, Hao;
Cui, Min

Publication type:

Article

Resveratrol Decreases the Invasion Potential of Gastric Cancer Cells.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3047, doi. 10.3390/molecules27103047

By:

Rojo, Daniel;
Madrid, Alejandro;
Martín, Sebastián San;
Párraga, Mario;
Silva Pinhal, Maria Aparecida;
Villena, Joan;
Valenzuela-Valderrama, Manuel

Publication type:

Article

The Challenge of Modulating Heparan Sulfate Turnover by Multitarget Heparin Derivatives.

Published in:

Molecules, 2020, v. 25, n. 2, p. 390, doi. 10.3390/molecules25020390

By:

Veraldi, Noemi;
Zouggari, Nawel;
de Agostini, Ariane;
Torri, Giangiacomo;
Fareed, Jawed;
Harenberg, Job

Publication type:

Article

Heparanase as an Additional Tool for Detecting Structural Peculiarities of Heparin Oligosaccharides.

Published in:

Molecules, 2019, v. 24, n. 23, p. 4403, doi. 10.3390/molecules24234403

By:

Alekseeva, Anna;
Urso, Elena;
Mazzini, Giulia;
Naggi, Annamaria;
Torri, Giangiacomo;
Fareed, Jawed;
Harenberg, Job

Publication type:

Article

The Development of Assays for Heparanase Enzymatic Activity: Towards a Gold Standard.

Published in:

Molecules, 2018, v. 23, n. 11, p. 2971, doi. 10.3390/molecules23112971

By:

Chhabra, Mohit;
Ferro, Vito;
Guerrini, Marco

Publication type:

Article

Serum Heparanase Level Is Decreased in Stable Coronary Artery Disease.

Published in:

2019

By:

Gurbuz, Ahmet Seyfeddin;
Ozturk, Semi;
Efe, Suleyman Cagan;
Yilmaz, Mehmet Fatih;
Yanik, Raziye Ecem;
Yaman, Ali;
Kirma, Cevat;
Gurbuz, Ahmet Seyfeddin;
Efe, Suleyman Cagan;
Yilmaz, Mehmet Fatih;
Yanik, Raziye Ecem

Publication type:

journal article

Specific heparanase inhibition reverses glucose-induced mesothelial-to-mesenchymal transition.

Published in:

Nephrology Dialysis Transplantation, 2017, v. 32, n. 7, p. 1145, doi. 10.1093/ndt/gfw403

By:

Masola, Valentina;
Granata, Simona;
Bellin, Gloria;
Gambaro, Giovanni;
Onisto, Maurizio;
Rugiu, Carlo;
Lupo, Antonio;
Zaza, Gianluigi

Publication type:

Article

RENAL TRANSPLANTATION EXPERIMENTAL AND INFLAMMATION.

Published in:: 2017
Publication type:: Abstract

Sulodexide and glycosaminoglycans in the progression of renal disease.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. suppl_1, p. i74, doi. 10.1093/ndt/gft389

By:

Masola, Valentina;
Zaza, Gianluigi;
Gambaro, Giovanni

Publication type:

Article

The role of heparanase and the endothelial glycocalyx in the development of proteinuria.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. 1, p. 49, doi. 10.1093/ndt/gft410

By:

Garsen, Marjolein;
Rops, Angelique L.W.M.M.;
Rabelink, Ton J.;
Berden, Jo H.M.;
van der Vlag, Johan

Publication type:

Article

Urinary heparanase activity in patients with Type 1 and Type 2 diabetes.

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 7, p. 2853, doi. 10.1093/ndt/gfr732

By:

Rops, Angelique L.W.M.M.;
van den Hoven, Mabel J.;
Veldman, Bart A.;
Salemink, Simone;
Vervoort, Gerald;
Elving, Lammy D.;
Aten, Jan;
Wetzels, Jack F.;
van der Vlag, Johan;
Berden, Jo H.M.

Publication type:

Article

Radiation-Induced Nephropathy in the Murine Model Is Ameliorated by Targeting Heparanase.

Published in:

Biomedicines, 2023, v. 11, n. 3, p. 710, doi. 10.3390/biomedicines11030710

By:

Abecassis, Alexia;
Hermano, Esther;
Sheva, Kim;
Rubinstein, Ariel M.;
Elkin, Michael;
Meirovitz, Amichay

Publication type:

Article

Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity fluid in women with impaired reproduction.

Published in:

Journal of Medical Science, 2014, v. 83, n. 4, p. 313, doi. 10.20883/medical.e83

By:

Wirstlein, Przemysław;
Mikołajczyk, Mateusz;
Skrzypczak, Jana

Publication type:

Article

Heparanase expression and glycosaminoglycans profile in renal cell carcinoma.

Published in:

International Journal of Urology, 2012, v. 19, n. 11, p. 1036, doi. 10.1111/j.1442-2042.2012.03086.x

By:

Batista, Lucas Teixeira e Aguiar;
Matos, Leandro Luongo;
Machado, Leopoldo Ruiz;
Suarez, Eloah Rabello;
Theodoro, Thérèse Rachell;
Martins, João Roberto Maciel;
Nader, Helena Bonciani;
Pompeo, Antonio Carlos Lima;
Pinhal, Maria Aparecida da Silva

Publication type:

Article

Author Correction: Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling.

Published in:

2021

By:

Kiyan, Yulia;
Tkachuk, Sergey;
Kurselis, Kestutis;
Shushakova, Nelli;
Stahl, Klaus;
Dawodu, Damilola;
Kiyan, Roman;
Chichkov, Boris;
Haller, Hermann

Publication type:

Correction Notice

Heparanase inhibition preserves the endothelial glycocalyx in lung grafts and improves lung preservation and transplant outcomes.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91777-0

By:

Noda, Kentaro;
Philips, Brian J.;
Snyder, Mark E.;
Phillippi, Julie A.;
Sullivan, Mara;
Stolz, Donna B.;
Ren, Xi;
Luketich, James D.;
Sanchez, Pablo G.

Publication type:

Article

Editorial: Molecules of the extracellular matrix as cancer targets.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.1034646

By:

Karamanos, Nikos K.;
Götte, Martin;
Passi, Alberto

Publication type:

Article

Heparanase Is a Putative Mediator of Endothelial Glycocalyx Damage in COVID-19 – A Proof-of-Concept Study.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.916512

By:

Drost, Carolin Christina;
Rovas, Alexandros;
Osiaevi, Irina;
Rauen, Matthias;
van der Vlag, Johan;
Buijsers, Baranca;
Salmenov, Rustem;
Lukasz, Alexander;
Pavenstädt, Hermann;
Linke, Wolfgang A.;
Kümpers, Philipp

Publication type:

Article

Expression of heparanase in soft tissue sarcomas of adults.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2014, v. 33, n. 1, p. 1, doi. 10.1186/1756-9966-33-39

By:

Kazarin, Olga;
Ilan, Neta;
Naroditzky, Inna;
Ben-Itzhak, Ofer;
Vlodavsky, Israel;
Bar-Sela, Gil

Publication type:

Article

Serum heparanase levels are associated with endothelial dysfunction in patients with obstructive sleep apnea.

Published in:

Clinical Respiratory Journal, 2018, v. 12, n. 4, p. 1693, doi. 10.1111/crj.12731

By:

Ozkok, Abdullah;
Ozkok, Sercin;
Takır, Mumtaz;
Yakar, Halil İbrahim;
Kanbay, Asiye

Publication type:

Article

Heparanase is a prognostic biomarker independent of tumor purity and hypoxia based on bioinformatics and immunohistochemistry analysis of esophageal squamous cell carcinoma.

Published in:

World Journal of Surgical Oncology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12957-022-02698-9

By:

Wang, Yu;
Song, Tongjun;
Li, Kai;
Liu, Hao;
Han, Yan;
Xu, Tao;
Cao, Fengjun;
Li, Yong;
Yu, Yuandong

Publication type:

Article

Heparanase is a prognostic biomarker independent of tumor purity and hypoxia based on bioinformatics and immunohistochemistry analysis of esophageal squamous cell carcinoma.

Published in:

World Journal of Surgical Oncology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12957-022-02698-9

By:

Wang, Yu;
Song, Tongjun;
Li, Kai;
Liu, Hao;
Han, Yan;
Xu, Tao;
Cao, Fengjun;
Li, Yong;
Yu, Yuandong

Publication type:

Article

Impact of heparanase on renal fibrosis.

Published in:

Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0538-5

By:

Masola, Valentina;
Zaza, Gianluigi;
Onisto, Maurizio;
Lupo, Antonio;
Gambaro, Giovanni

Publication type:

Article

Everolimus-induced epithelial to mesenchymal transition in immortalized human renal proximal tubular epithelial cells: key role of heparanase.

Published in:

Journal of Translational Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1479-5876-11-292

By:

Masola, Valentina;
Gianluigi Zaza;
Granata, Simona;
Gambaro, Giovanni;
Onisto, Maurizio;
Lupo, Antonio

Publication type:

Article

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity.

Published in:

2017

By:

Baburajeev, C. P.;
Mohan, Chakrabhavi Dhananjaya;
Rangappa, Shobith;
Mason, Daniel J.;
Fuchs, Julian E.;
Bender, Andreas;
Barash, Uri;
Vlodavsky, Israel;
Basappa;
Rangappa, Kanchugarakoppal S.

Publication type:

journal article

Demystifying the pH dependent conformational changes of human heparanase pertaining to structure-function relationships: an in silico approach.

Published in:

Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 8, p. 821, doi. 10.1007/s10822-018-0131-0

By:

Nagarajan, Hemavathy;
Vetrivel, Umashankar

Publication type:

Article

Overexpression of heparanase attenuated TGF-β-stimulated signaling in tumor cells.

Published in:

FEBS Open Bio, 2017, v. 7, n. 3, p. 405, doi. 10.1002/2211-5463.12190

By:

Batool, Tahira;
Fang, Jianping;
Barash, Uri;
Moustakas, Aristidis;
Vlodavsky, Israel;
Li, Jin-Ping

Publication type:

Article

Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues.

Published in:

FEBS Open Bio, 2013, v. 3, p. 346, doi. 10.1016/j.fob.2013.07.007

By:

Hammond, Edward;
Handley, Paul;
Dredge, Keith;
Bytheway, Ian

Publication type:

Article

Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues.

Published in:

FEBS Open Bio, 2013, v. 3, n. 1, p. 346, doi. 10.1016/j.fob.2013.07.007

By:

Hammond, Edward;
Handley, Paul;
Dredge, Keith;
Bytheway, Ian

Publication type:

Article

Upregulation of ERK-EGR1-heparanase axis by HDAC inhibitors provides targets for rational therapeutic intervention in synovial sarcoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-02150-y

By:

Lanzi, Cinzia;
Favini, Enrica;
Dal Bo, Laura;
Tortoreto, Monica;
Arrighetti, Noemi;
Zaffaroni, Nadia;
Cassinelli, Giuliana

Publication type:

Article

Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164183

By:

Asperti, Michela;
Stuemler, Tanja;
Poli, Maura;
Gryzik, Magdalena;
Lifshitz, Lena;
Meyron-Holtz, Esther G.;
Vlodavsky, Israel;
Arosio, Paolo

Publication type:

Article

Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160894

By:

Garsen, Marjolein;
Rops, Angelique L.;
Li, Jinhua;
van Beneden, Katrien;
van den Branden, Christiane;
Berden, Jo HM;
Rabelink, Ton J.;
van der Vlag, Johan

Publication type:

Article

Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury.

Published in:

PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0160074

By:

Masola, Valentina;
Zaza, Gianluigi;
Gambaro, Giovanni;
Onisto, Maurizio;
Bellin, Gloria;
Vischini, Gisella;
Khamaysi, Iyad;
Hassan, Ahmad;
Hamoud, Shadi;
Nativ, Omri;
N. Heyman, Samuel;
Lupo, Antonio;
Vlodavsky, Israel;
Abassi, Zaid

Publication type:

Article