Works matching DE "HEPARANASE"

Results: 258

Assays for hyaluronidases and heparanase using nonreducing end fluorophore-labeled hyaluronan and heparan sulfate proteoglycan.

Published in:

Glycobiology, 2021, v. 31, n. 11, p. 1435, doi. 10.1093/glycob/cwab061

By:

Wu, Zhengliang L;
Ertelt, James M

Publication type:

Article

Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei.

Published in:

Glycobiology, 2019, v. 29, n. 8, p. 572, doi. 10.1093/glycob/cwz039

By:

Yu, Yanlei;
Williams, Asher;
Zhang, Xing;
Fu, Li;
Xia, Ke;
Xu, Yongmei;
Zhang, Fuming;
Liu, Jian;
Koffas, Mattheos;
Linhardt, Robert J

Publication type:

Article

Overexpression of heparanase in mice promoted megakaryopoiesis.

Published in:

Glycobiology, 2018, v. 28, n. 5, p. 269, doi. 10.1093/glycob/cwy011

By:

Ying-Xia Tan;
Hao Cui;
Lu-Ming Wan;
Feng Gong;
Xiao Zhang;
Israel Vlodavsky;
Jin-Ping Li

Publication type:

Article

Non-reducing end labeling of heparan sulfate via click chemistry and a high throughput ELISA assay for heparanase.

Published in:

Glycobiology, 2017, v. 27, n. 6, p. 518, doi. 10.1093/glycob/cww130

By:

Wu, Zhengliang L.;
Xinyi Huang;
Ethen, Cheryl M.;
Tatge, Timothy;
Pasek, Marta;
Zaia, Joseph

Publication type:

Article

Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase.

Published in:

Glycobiology, 2016, v. 26, n. 6, p. 640, doi. 10.1093/glycob/cww003

By:

Pala, Daniele;
Rivara, Silvia;
Mor, Marco;
Milazzo, Ferdinando Maria;
Roscilli, Giuseppe;
Pavoni, Emiliano;
Giannini, Giuseppe

Publication type:

Article

Glycosaminoglycans affect heparanase location in CHO cell lines.

Published in:

Glycobiology, 2015, v. 25, n. 9, p. 976, doi. 10.1093/glycob/cwv035

By:

Piva, Maria B. R.;
Suarez, Eloah R.;
Melo, Carina M.;
Cavalheiro, Renan P.;
Nader, Helena B.;
Pinhal, Maria A. S.

Publication type:

Article

Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and cellular recruitment.

Published in:

Glycobiology, 2015, v. 25, n. 4, p. 386, doi. 10.1093/glycob/cwu119

By:

Gomes, Angélica Maciel;
Oliveira Kozlowski, Eliene;
Borsig, Lubor;
Teixeira, Felipe COB;
Vlodavsky, Israel;
Pavão, Mauro S. G.

Publication type:

Article

Application of bioinformatics analysis to construct the prognostic model and immune-related gene characteristics of low-grade glioma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02639-4

By:

Liao, Peng;
Zhang, Xiaocui;
Yuan, Ruyan;
Tang, Tingjun;
Wang, Feng;
Geng, Baowei

Publication type:

Article

Multi-omics insights into the roles of CCNB1, PLK1, and HPSE in breast cancer progression: implications for prognosis and immunotherapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02282-z

By:

Su, Qisheng;
Fang, Leiming;
Li, Chaofan;
Yue, Liang;
Yun, Zhimin;
Zhang, Huiqiang;
Liu, Qi;
Ma, Ruilin;
Zhong, Pengfei;
Liu, He;
Lou, Zhangrong;
Chen, Zhi;
Tan, Yingxia;
Hao, Xiaopeng;
Wu, Chengjun

Publication type:

Article

Multi-omics insights into the roles of CCNB1, PLK1, and HPSE in breast cancer progression: implications for prognosis and immunotherapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02282-z

By:

Su, Qisheng;
Fang, Leiming;
Li, Chaofan;
Yue, Liang;
Yun, Zhimin;
Zhang, Huiqiang;
Liu, Qi;
Ma, Ruilin;
Zhong, Pengfei;
Liu, He;
Lou, Zhangrong;
Chen, Zhi;
Tan, Yingxia;
Hao, Xiaopeng;
Wu, Chengjun

Publication type:

Article

The Potential Impact of Heparanase Activity and Endothelial Damage in COVID-19 Disease.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 18, p. N.PAG, doi. 10.3390/jcm11185261

By:

Zechendorf, Elisabeth;
Schröder, Katharina;
Stiehler, Lara;
Frank, Nadine;
Beckers, Christian;
Kraemer, Sandra;
Dreher, Michael;
Kersten, Alexander;
Thiemermann, Christoph;
Marx, Gernot;
Simon, Tim-Philipp;
Martin, Lukas

Publication type:

Article

Heparanase Inhibition Prevents Liver Steatosis in E 0 Mice.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 6, p. 1672, doi. 10.3390/jcm11061672

By:

Kinaneh, Safa;
Hijaze, Walaa;
Mansour-Wattad, Lana;
Hammoud, Rawan;
Zaidani, Hisam;
Kabala, Aviva;
Hamoud, Shadi

Publication type:

Article

Impact of Adjuvant Treatment on Heparanase Concentration in Invasive, Unilateral Breast Cancer Patients: Results of a Prospective Single-Centre Cohort Study.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 10, p. 2184, doi. 10.3390/jcm10102184

By:

Ruszkowska-Ciastek, Barbara;
Bielawski, Kornel;
Zarychta, Elżbieta;
Rhone, Piotr;
Wu, Yanyuan

Publication type:

Article

Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00331

By:

Mayfosh, Alyce J.;
Baschuk, Nikola;
Hulett, Mark D.

Publication type:

Article

Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00216

By:

Liu, Xue;
Zhou, Zhi-hang;
Li, Wen;
Zhang, Shi-kun;
Li, Jing;
Zhou, Ming-Ju;
Song, Jin-Wen

Publication type:

Article

Methylene blue photodynamic therapy in malignant melanoma decreases expression of proliferating cell nuclear antigen and heparanases.

Published in:

Clinical & Experimental Dermatology, 2012, v. 37, n. 5, p. 527, doi. 10.1111/j.1365-2230.2011.04291.x

By:

Wagner, M.;
Suarez, E. R.;
Theodoro, T. R.;
Machado Filho, C. D. A. S.;
Gama, M. F. M.;
Tardivo, J. P.;
Paschoal, F. M.;
Pinhal, M. A. S.

Publication type:

Article

Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 1, p. 794, doi. 10.3892/mmr.2017.6638

By:

Yi Zhang;
Xu Sun;
Nan Nan;
Ke-Xin Cao;
Cong Ma;
Guo-Wang Yang;
Ming-Wei Yu;
Lin Yang;
Jin-Ping Li;
Xiao-Min Wang;
Gan-Lin Zhang

Publication type:

Article

Effects of unfractionated heparin and rivaroxaban on the expression of heparanase and fibroblast growth factor 2 in human osteoblasts.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 1, p. 361, doi. 10.3892/mmr.2017.6570

By:

Jingjun Xia;
Wei Sheng;
Liubao Pei;
Ning Li;
Zhipeng Zhang;
Jialiang Wang;
Jianing Zu;
Nanxiang Wang;
Duanyang Wang

Publication type:

Article

Heparanase 2 Modulation Inhibits HSV-2 Replication by Regulating Heparan Sulfate.

Published in:

Viruses (1999-4915), 2024, v. 16, n. 12, p. 1832, doi. 10.3390/v16121832

By:

Hopkins, James;
Volety, Ipsita;
Qatanani, Farreh;
Shukla, Deepak

Publication type:

Article

Heparanase-1: From Cancer Biology to a Future Antiviral Target.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 1, p. 237, doi. 10.3390/v15010237

By:

Lebsir, Nadjet;
Zoulim, Fabien;
Grigorov, Boyan

Publication type:

Article

Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/v14102156

By:

Sharma, Pankaj;
Kapoor, Divya;
Shukla, Deepak

Publication type:

Article

CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 6, p. N.PAG, doi. 10.3390/v14061171

By:

Yadavalli, Tejabhiram;
Sharma, Pankaj;
Wu, David;
Kapoor, Divya;
Shukla, Deepak

Publication type:

Article

Increased Heparanase Levels in Urine during Acute Puumala Orthohantavirus Infection Are Associated with Disease Severity.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 3, p. 450, doi. 10.3390/v14030450

By:

Cabrera, Luz E.;
Schmotz, Constanze;
Saleem, Moin A.;
Lehtonen, Sanna;
Vapalahti, Olli;
Vaheri, Antti;
Mäkelä, Satu;
Mustonen, Jukka;
Strandin, Tomas

Publication type:

Article

Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 9, p. 1748, doi. 10.3390/v13091748

By:

Karasneh, Ghadah A.;
Kapoor, Divya;
Bellamkonda, Navya;
Patil, Chandrashekhar D.;
Shukla, Deepak

Publication type:

Article

In silico investigation of heparanase-correlated genes in breast cancer subtypes.

Published in:

Einstein (16794508), 2020, v. 18, p. 1, doi. 10.31744/einstein_journal/2020AO5447

By:

Mucciolo Melo, Carina;
Pereira Prado, Henrique;
Araújo Attie, Gabriela;
Lacaz Ruiz, Daniel;
Batista Castello Girão, Manoel João;
da Silva Pinhal, Maria Aparecida

Publication type:

Article

Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses.

Published in:

Journal of Orthopaedic Research, 2022, v. 40, n. 10, p. 2391, doi. 10.1002/jor.25260

By:

Mundy, Christina;
Chung, Juliet;
Koyama, Eiki;
Bunting, Stuart;
Mahimkar, Rajeev;
Pacifici, Maurizio

Publication type:

Article

Invasion and metastasis of renal cell carcinoma.

Published in:

Medical Molecular Morphology, 2014, v. 47, n. 2, p. 63, doi. 10.1007/s00795-013-0064-6

By:

Mikami, Shuji;
Oya, Mototsugu;
Mizuno, Ryuichi;
Kosaka, Takeo;
Katsube, Ken-ichi;
Okada, Yasunori

Publication type:

Article

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity.

Published in:

2017

By:

Baburajeev, C. P.;
Mohan, Chakrabhavi Dhananjaya;
Rangappa, Shobith;
Mason, Daniel J.;
Fuchs, Julian E.;
Bender, Andreas;
Barash, Uri;
Vlodavsky, Israel;
Basappa;
Rangappa, Kanchugarakoppal S.

Publication type:

journal article

Structural Insights into Pixatimod (PG545) Inhibition of Heparanase, a Key Enzyme in Cancer and Viral Infections.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 10, p. 1, doi. 10.1002/chem.202104222

By:

Chhabra, Mohit;
Wilson, Jennifer C.;
Wu, Liang;
Davies, Gideon J.;
Gandhi, Neha S.;
Ferro, Vito

Publication type:

Article

Synthetic Heparanase Inhibitors Can Prevent Herpes Simplex Viral Spread.

Published in:

Angewandte Chemie, 2023, v. 135, n. 41, p. 1, doi. 10.1002/ange.202309838

By:

Chopra, Pradeep;
Yadavalli, Tejabhiram;
Palmieri, Francesco;
Jongkees, Seino A. K.;
Unione, Luca;
Shukla, Deepak;
Boons, Geert‐Jan

Publication type:

Article

Rational Design and Expedient Synthesis of Heparan Sulfate Mimetics from Natural Aminoglycosides for Structure and Activity Relationship Studies.

Published in:

Angewandte Chemie, 2023, v. 135, n. 32, p. 1, doi. 10.1002/ange.202304325

By:

Wakpal, Joseph;
Pathiranage, Vishaka;
Walker, Alice R.;
Nguyen, Hien M.

Publication type:

Article

On the Biology of Werner's Complex.

Published in:

Angewandte Chemie, 2021, v. 133, n. 31, p. 17260, doi. 10.1002/ange.202105019

By:

Paiva, Raphael E. F.;
Peterson, Erica J.;
Malina, Jaroslav;
Zoepfl, Mary;
Hampton, J. David;
Johnson, Wyatt E.;
Graminha, Angelica;
Ourahmane, Amine;
McVoy, Michael A.;
Brabec, Viktor;
Berners‐Price, Susan J.;
Farrell, Nicholas P.

Publication type:

Article

Specific heparanase inhibition reverses glucose-induced mesothelial-to-mesenchymal transition.

Published in:

Nephrology Dialysis Transplantation, 2017, v. 32, n. 7, p. 1145, doi. 10.1093/ndt/gfw403

By:

Masola, Valentina;
Granata, Simona;
Bellin, Gloria;
Gambaro, Giovanni;
Onisto, Maurizio;
Rugiu, Carlo;
Lupo, Antonio;
Zaza, Gianluigi

Publication type:

Article

RENAL TRANSPLANTATION EXPERIMENTAL AND INFLAMMATION.

Published in:: 2017
Publication type:: Abstract

Sulodexide and glycosaminoglycans in the progression of renal disease.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. suppl_1, p. i74, doi. 10.1093/ndt/gft389

By:

Masola, Valentina;
Zaza, Gianluigi;
Gambaro, Giovanni

Publication type:

Article

The role of heparanase and the endothelial glycocalyx in the development of proteinuria.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. 1, p. 49, doi. 10.1093/ndt/gft410

By:

Garsen, Marjolein;
Rops, Angelique L.W.M.M.;
Rabelink, Ton J.;
Berden, Jo H.M.;
van der Vlag, Johan

Publication type:

Article

Urinary heparanase activity in patients with Type 1 and Type 2 diabetes.

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 7, p. 2853, doi. 10.1093/ndt/gfr732

By:

Rops, Angelique L.W.M.M.;
van den Hoven, Mabel J.;
Veldman, Bart A.;
Salemink, Simone;
Vervoort, Gerald;
Elving, Lammy D.;
Aten, Jan;
Wetzels, Jack F.;
van der Vlag, Johan;
Berden, Jo H.M.

Publication type:

Article

Heparanase 1 involvement in prostate physiopathology.

Published in:

Cell Biology International, 2017, v. 41, n. 11, p. 1194, doi. 10.1002/cbin.10748

By:

Barbosa, Guilherme O.;
Cervigne, Nilva K.;
Carvalho, Hernandes F.;
Augusto, Taize M.

Publication type:

Article

Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage.

Published in:

Renal Failure, 2017, v. 39, n. 1, p. 698, doi. 10.1080/0886022X.2017.1384391

By:

Zhao, Yue;
Liu, Jingshun;
Ten, Shichao;
Zhang, Jisheng;
Yuan, Yanggang;
Yu, Jiangyi;
An, Xiaofei

Publication type:

Article

Radiation-Induced Nephropathy in the Murine Model Is Ameliorated by Targeting Heparanase.

Published in:

Biomedicines, 2023, v. 11, n. 3, p. 710, doi. 10.3390/biomedicines11030710

By:

Abecassis, Alexia;
Hermano, Esther;
Sheva, Kim;
Rubinstein, Ariel M.;
Elkin, Michael;
Meirovitz, Amichay

Publication type:

Article

MicroRNA-429 decreases the invasion ability of gastric cancer cell line BGC-823 by downregulating the expression of heparanase.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 2, p. 1927, doi. 10.3892/etm.2017.5608

By:

Sheng, Nan;
Zhang, Lin;
Yang, Shaofeng

Publication type:

Article

Evaluation of the C-domain of heparanase during AGE-induced macrophage inflammatory response.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 2, p. 1017, doi. 10.3892/etm.2017.4609

By:

QIAOJING QIN;
GUANG XU;
WEIWEI QI;
MEI GUO;
ZHAOXIA WANG;
WANGJIE XU;
ZHONGDONG QIAO;
YONG GU;
JIANYING NIU

Publication type:

Article

Protective effects of Danggui Buxue Tang on renal function, renal glomerular mesangium and heparanase expression in rats with streptozotocin-induced diabetes mellitus.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 11, n. 6, p. 2477, doi. 10.3892/etm.2016.3218

By:

TAI-SHENG YE;
YING-WEN ZHANG;
XIAN-MEI ZHANG

Publication type:

Article

A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis.

Published in:

Cells (2073-4409), 2024, v. 13, n. 3, p. 211, doi. 10.3390/cells13030211

By:

Li, Li;
Barash, Uri;
Ilan, Neta;
Farhoud, Malik;
Zhang, Xiao;
Vlodavsky, Israel;
Li, Jin-Ping

Publication type:

Article

Role of a Novel Heparanase Inhibitor on the Balance between Apoptosis and Autophagy in U87 Human Glioblastoma Cells.

Published in:

Cells (2073-4409), 2023, v. 12, n. 14, p. 1891, doi. 10.3390/cells12141891

By:

Manganelli, Valeria;
Misasi, Roberta;
Riitano, Gloria;
Capozzi, Antonella;
Mattei, Vincenzo;
Caglar, Tuba Rana;
Ialongo, Davide;
Madia, Valentina Noemi;
Messore, Antonella;
Costi, Roberta;
Di Santo, Roberto;
Sorice, Maurizio;
Garofalo, Tina

Publication type:

Article

Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma.

Published in:

Cells (2073-4409), 2023, v. 12, n. 6, p. 913, doi. 10.3390/cells12060913

By:

Ostrovsky, Olga;
Beider, Katia;
Magen, Hila;
Leiba, Merav;
Sanderson, Ralph D.;
Vlodavsky, Israel;
Nagler, Arnon

Publication type:

Article

Heparanase Modulates Chromatin Accessibility.

Published in:

Cells (2073-4409), 2023, v. 12, n. 6, p. 891, doi. 10.3390/cells12060891

By:

Li, Honglian;
Zhang, Hua;
Wenz, Amelie;
Kang, Ziqi;
Wang, Helen;
Vlodavsky, Israel;
Chen, Xingqi;
Li, Jinping

Publication type:

Article

Opposing Roles of IGFBP-3 and Heparanase in Regulating A549 Lung Cancer Cell Survival.

Published in:

Cells (2073-4409), 2022, v. 11, n. 22, p. 3533, doi. 10.3390/cells11223533

By:

Al Khashali, Hind;
Wareham, Jadziah;
Ray, Ravel;
Haddad, Ben;
Coleman, Kai-Ling;
Ranzenberger, Robert;
McCombs, Patrick;
Guthrie, Jeffrey;
Heyl, Deborah;
Evans, Hedeel Guy

Publication type:

Article

Heparanase: A Novel Therapeutic Target for the Treatment of Atherosclerosis.

Published in:

Cells (2073-4409), 2022, v. 11, n. 20, p. 3198, doi. 10.3390/cells11203198

By:

Nguyen, Tien K.;
Paone, Stephanie;
Chan, Enoch;
Poon, Ivan K. H.;
Baxter, Amy A.;
Thomas, Shane R.;
Hulett, Mark D.

Publication type:

Article

Macrophages Upregulate Estrogen Receptor Expression in the Model of Obesity-Associated Breast Carcinoma.

Published in:

Cells (2073-4409), 2022, v. 11, n. 18, p. N.PAG, doi. 10.3390/cells11182844

By:

Nahmias Blank, Daniela;
Hermano, Esther;
Sonnenblick, Amir;
Maimon, Ofra;
Rubinstein, Ariel M.;
Drai, Emmy;
Maly, Bella;
Vlodavsky, Israel;
Popovtzer, Aron;
Peretz, Tamar;
Meirovitz, Amichay;
Elkin, Michael

Publication type:

Article