Works matching DE "HEDGEHOG signaling proteins"
Results: 1508
Casticin inhibits the hedgehog signaling and leads to apoptosis in AML stem-like KG1a and mature KG1 cells.
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- Turkish Journal of Biochemistry / Turk Biyokimya Dergisi, 2025, v. 50, n. 1, p. 62, doi. 10.1515/tjb-2024-0149
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The Drosophila epidermal growth factor receptor pathway regulates Hedgehog signalling and cytoneme behaviour.
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- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57162-5
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Synthesis and Evaluation of Aromatic A-Ring 23-Oxavitamin D 3 Analogues as Hedgehog Pathway Inhibitors.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1631, doi. 10.3390/ijms26041631
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Notch and Hedgehog Signaling Unveiled: Crosstalk, Roles, and Breakthroughs in Cancer Stem Cell Research.
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- Life (2075-1729), 2025, v. 15, n. 2, p. 228, doi. 10.3390/life15020228
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Hedgehog signaling is activated in canine transitional cell carcinoma and contributes to cell proliferation and survival.
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- Veterinary & Comparative Oncology, 2017, v. 15, n. 1, p. 174, doi. 10.1111/vco.12149
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Exploring the Potential of Anthraquinone‐Based Hybrids for Identifying a Novel Generation of Antagonists for the Smoothened Receptor in HH‐Dependent Tumour.
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- Chemistry - A European Journal, 2023, v. 29, n. 62, p. 1, doi. 10.1002/chem.202302237
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Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone.
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- Chemistry - A European Journal, 2022, v. 28, n. 67, p. 1, doi. 10.1002/chem.202202164
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The Pseudo‐Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2.
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- Angewandte Chemie, 2024, v. 136, n. 32, p. 1, doi. 10.1002/ange.202404645
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Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT).
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- Angewandte Chemie, 2021, v. 133, n. 24, p. 13654, doi. 10.1002/ange.202014457
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Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß.
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- Angewandte Chemie, 2019, v. 131, n. 46, p. 16770, doi. 10.1002/ange.201907632
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Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.
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- Angewandte Chemie, 2019, v. 131, n. 4, p. 1074, doi. 10.1002/ange.201810312
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Disruption of the creb3l1 gene causes defects in caudal fin regeneration and patterning in zebrafish Danio rerio.
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- Developmental Dynamics, 2024, v. 253, n. 12, p. 1106, doi. 10.1002/dvdy.726
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Primary cilia are critical for tracheoesophageal septation.
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- Developmental Dynamics, 2024, v. 253, n. 3, p. 312, doi. 10.1002/dvdy.660
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Editorial Highlights.
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- Developmental Dynamics, 2023, v. 252, n. 4, p. 444, doi. 10.1002/dvdy.587
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Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.
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- Developmental Dynamics, 2023, v. 252, n. 4, p. 483, doi. 10.1002/dvdy.555
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A transgenic Alx4‐CreER mouse to analyze anterior limb and nephric duct development.
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- Developmental Dynamics, 2022, v. 251, n. 9, p. 1524, doi. 10.1002/dvdy.328
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Unique lingual expression of the Hedgehog pathway antagonist Hedgehog‐interacting protein in filiform papillae during homeostasis and ectopic expression in fungiform papillae during Hedgehog signaling inhibition.
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- Developmental Dynamics, 2022, v. 251, n. 7, p. 1175, doi. 10.1002/dvdy.456
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Defining the critical period of hedgehog pathway inhibitor‐induced cranial base dysplasia in mice.
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- Developmental Dynamics, 2021, v. 250, n. 4, p. 527, doi. 10.1002/dvdy.270
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The formation of multiple pituitary pouches from the oral ectoderm causes ectopic lens development in hedgehog signaling‐defective avian embryos.
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- Developmental Dynamics, 2020, v. 249, n. 12, p. 1425, doi. 10.1002/dvdy.222
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A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype.
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- Developmental Dynamics, 2007, v. 236, n. 3, p. 769, doi. 10.1002/dvdy.21082
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Temporomandibular joint formation and condyle growth require Indian hedgehog signaling.
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- Developmental Dynamics, 2007, v. 236, n. 2, p. 426, doi. 10.1002/dvdy.21036
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The hedgehog‐related gene qua‐1 is required for molting in Caenorhabditis elegans.
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- Developmental Dynamics, 2006, v. 235, n. 6, p. 1469
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Roles of Myofibroblasts and Notch and Hedgehog Signaling Pathways in the Formation of Intrahepatic Bile Duct Lesions in Polycystic Kidney Rats.
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- Pediatric & Developmental Pathology, 2013, v. 16, n. 3, p. 177, doi. 10.2350/12-11-1267-OA.1
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Dexamethasone induces osteogenesis via regulation of hedgehog signalling molecules in rat mesenchymal stem cells.
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- International Orthopaedics, 2013, v. 37, n. 7, p. 1399, doi. 10.1007/s00264-013-1902-9
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Growth plate-derived hedgehog-signal-responsive cells provide skeletal tissue components in growing bone.
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- Histochemistry & Cell Biology, 2018, v. 149, n. 4, p. 365, doi. 10.1007/s00418-018-1641-5
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Expression analysis of Shh signaling members in early stages of chick lung development.
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- Histochemistry & Cell Biology, 2016, v. 146, n. 4, p. 457, doi. 10.1007/s00418-016-1448-1
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GAS1 is present in the cerebrospinal fluid and is expressed in the choroid plexus of the adult rat.
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- Histochemistry & Cell Biology, 2016, v. 146, n. 3, p. 325, doi. 10.1007/s00418-016-1449-0
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SULF1/SULF2 reactivation during liver damage and tumour growth.
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- Histochemistry & Cell Biology, 2016, v. 146, n. 1, p. 85, doi. 10.1007/s00418-016-1425-8
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BMP4 signaling mediates Zeb family in developing mouse tooth.
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- Histochemistry & Cell Biology, 2012, v. 137, n. 6, p. 791, doi. 10.1007/s00418-012-0930-7
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Immunohistochemical evaluation of Sonic Hedgehog signaling pathway proteins (Shh, Ptch1, Ptch2, Smo, Gli1, Gli2, and Gli3) in sporadic and syndromic odontogenic keratocysts.
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- Clinical Oral Investigations, 2019, v. 23, n. 1, p. 153, doi. 10.1007/s00784-018-2421-2
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Prognostic significance of the methylation of Wnt pathway antagonists- CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling- ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas.
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- Clinical Oral Investigations, 2017, v. 21, n. 5, p. 1777, doi. 10.1007/s00784-016-1946-5
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Relation between sonic hedgehog pathway gene polymorphisms and basal cell carcinoma development in the Polish population.
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- Archives of Dermatological Research, 2016, v. 308, n. 1, p. 39, doi. 10.1007/s00403-015-1612-9
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Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis.
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- Archives of Dermatological Research, 2013, v. 305, n. 1, p. 1, doi. 10.1007/s00403-012-1304-7
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Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice.
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- Archives of Dermatological Research, 2001, v. 293, n. 9, p. 435, doi. 10.1007/s004030100252
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Targeting triple negative breast cancer stem cells using nanocarriers.
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- Discover Nano, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s11671-024-03985-y
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Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus.
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- Nature Immunology, 2006, v. 7, n. 4, p. 418, doi. 10.1038/ni1313
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DHH pathogenic variants involved in 46,XY disorders of sex development differentially impact protein self-cleavage and structural conformation.
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- Human Genetics, 2020, v. 139, n. 11, p. 1455, doi. 10.1007/s00439-020-02189-5
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Targeted panel sequencing establishes the implication of planar cell polarity pathway and involves new candidate genes in neural tube defect disorders.
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- Human Genetics, 2019, v. 138, n. 4, p. 363, doi. 10.1007/s00439-019-01993-y
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Recovery of sweet taste preference in adult rats following bilateral chorda tympani nerve transection.
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- PeerJ, 2022, p. 1, doi. 10.7717/peerj.14455
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Hedgehog Drugs Begin To Show Results.
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- JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 10, p. 692, doi. 10.1093/jnci/djn169
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Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 349, doi. 10.1080/14756366.2017.1419221
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Lentivirus-mediated delivery of sonic hedgehog into the striatum stimulates neuroregeneration in a rat model of Parkinson disease.
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- Neurological Sciences, 2014, v. 35, n. 12, p. 1931, doi. 10.1007/s10072-014-1866-6
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Epithelial biology in the gastrointestinal system: insights into normal physiology and disease pathogenesis.
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- Journal of Physiology, 2012, v. 590, n. 3, p. 419, doi. 10.1113/jphysiol.2011.227058
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Hedgehog signalling in gut development, physiology and cancer.
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- Journal of Physiology, 2012, v. 590, n. 3, p. 421, doi. 10.1113/jphysiol.2011.220681
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Patched-1 and Smoothened, a Hedgehog Receptor and Signal Transducer are Highly Expressed in Diffuse Large B-Cell Lymphoma.
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- Malaysian Journal of Medicine & Health Sciences, 2017, v. 13, n. 2, p. 1
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The Efficacy of Sonidegib in Treating Locally Advanced Basal Cell Carcinoma Involving the Periocular Area.
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- Dermatology & Therapy, 2023, v. 13, n. 9, p. 2121, doi. 10.1007/s13555-023-00985-1
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Qualitative Patient Interviews to Characterize the Human Burden of Advanced Basal Cell Carcinoma Following Hedgehog Pathway Inhibitor Treatment.
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- Dermatology & Therapy, 2023, v. 13, n. 8, p. 1747, doi. 10.1007/s13555-023-00945-9
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Effects of Sonidegib Following Dose Reduction and Treatment Interruption in Patients with Advanced Basal Cell Carcinoma During 42-Month BOLT Trial.
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- Dermatology & Therapy, 2021, v. 11, n. 6, p. 2225, doi. 10.1007/s13555-021-00619-4
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Expression of Sonic hedgehog signaling molecules in normal, hyperplastic and carcinomatous endometrium.
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- Pathology International, 2009, v. 59, n. 5, p. 279, doi. 10.1111/j.1440-1827.2009.02366.x
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Hedgehog signalling in skin development and cancer.
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- Experimental Dermatology, 2006, v. 15, n. 9, p. 667, doi. 10.1111/j.1600-0625.2006.00473.x
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