Works matching DE "HEDGEHOG signaling proteins"

Results: 1561

MSC‐Derived Exosomal MiR‐127‐3p Alleviates Acute Kidney Ischemia–Reperfusion Injury via Suppressing ATG5/ATG7‐Mediated Autophagy.

Published in:

Nephrology, 2025, v. 30, n. 6, p. 1, doi. 10.1111/nep.70054

By:

Ji, Xiaobing;
Nie, Shuai;
Li, Xiangxiang;
Liu, Hao;
Du, Xin;
Fan, Li

Publication type:

Article

The hedgehog’s trick for escaping immunosurveillance.

Published in:

OncoImmunology, 2014, v. 3, n. 6, p. N.PAG, doi. 10.4161/onci.29180

By:

Xie, Jingwu

Publication type:

Article

Recurrent morphoeic basal cell carcinoma with metastatic progression in a 34-year-old patient: a case report.

Published in:

Clinical & Experimental Dermatology, 2025, v. 50, n. 6, p. 1201, doi. 10.1093/ced/llae537

By:

Afzal, Usamah M;
Ali, Faisal R;
Oudit, Deemesh;
Totorean, Roxana;
Shenjere, Patrick;
Lear, John T

Publication type:

Article

Calcium Fructoborate Improves Knee Osteoarthritis in Rats by Activating Hedgehog Signaling Through DDIT3.

Published in:

Biological Trace Element Research, 2025, v. 203, n. 7, p. 3803, doi. 10.1007/s12011-024-04454-4

By:

Yan, TingXin;
Wang, Peng;
Cao, Zhilin

Publication type:

Article

Hedgehog Signaling Functions in Spermatogenesis and Keeping Hemolymph–Testis Barrier Stability in Eriocheir sinensis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5378, doi. 10.3390/ijms26115378

By:

Yu, Jun-Jie;
Qi, Hong-Yu;
Zhao, Zhan;
Yang, Yu;
Zhang, Shuang-Yi;
Tan, Fu-Qing;
Yang, Wan-Xi

Publication type:

Article

Stromal Hedgehog Signaling Is Associated with Favorable Outcomes in Pancreatic Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5200, doi. 10.3390/ijms26115200

By:

Manoukian, Paul;
Damhofer, Helene;
Zhao, Lan;
van Laarhoven, Hanneke W. M.;
Bijlsma, Maarten F.

Publication type:

Article

Factors Involved in Enamel Knot Establishment and Cap Formation.

Published in:

Journal of Dental Research, 2025, v. 104, n. 7, p. 784, doi. 10.1177/00220345251316834

By:

Steklikova, K.;
Dalecka, L.;
Kubovciak, J.;
Corneloup, C.;
Pantalacci, S.;
Hovorakova, M.

Publication type:

Article

Remarkable Response to Vismodegib in a Locally Advanced Basal Cell Carcinoma on the Nose.

Published in:

Cutis, 2025, v. 115, n. 5, p. E9, doi. 10.12788/cutis.1228

By:

Mak, Evan;
Buck, Shannon

Publication type:

Article

Hedgehog Signaling during Gut Formation in the Freshwater Leech, Helobdella austinensis.

Published in:

Cells Tissues Organs, 2025, v. 214, n. 3, p. 194, doi. 10.1159/000543782

By:

Medina-Jiménez, Brenda I.;
Kwak, Hee-Jin;
Aryal, Yam Prasad;
Lee, Chan-Jun;
Jeong, Geon-Hwi;
Pyo, In-Hyeok;
Park, Hyeonwoo;
Kim, Sangjune;
Park, Soon Cheol;
Cho, Sung-Jin

Publication type:

Article

宫寒型反复种植失败患者子宫内膜蛋白质组学研究.

Published in:

Journal of International Reproductive Health/Family Planning, 2025, v. 44, n. 1, p. 1, doi. 10.12280/gjszjk.20240448

By:

宫政;
赵晓丽;
王宝娟;
董融;
刘凇含;
王聪;
夏天

Publication type:

Article

Combination Therapy for Overcoming Multidrug Resistance in Breast Cancer Through Hedgehog Signaling Pathway Regulation.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 572, doi. 10.3390/pharmaceutics17050572

By:

Liu, Yujie;
Yang, Yiliang;
Qi, Xianrong

Publication type:

Article

Short Tandem Repeat (STR) Somatic Mutation in Non-Melanoma Skin Cancer (NMSC): Association with Transcriptomic Profile and Potential Implications for Therapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1669, doi. 10.3390/cancers17101669

By:

Kibriya, Muhammad G.;
Almazan, Armando;
Argos, Maria;
Islam, Tariqul;
Shea, Christopher R.;
Ahsan, Habibul;
Jasmine, Farzana

Publication type:

Article

Research highlights.

Published in:

2010

By:

S. L.;
M. H.;
J. M. F.

Publication type:

Abstract

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 718, doi. 10.1038/nsmb.1833

By:

Lauth, Matthias;
Bergström, Åsa;
Shimokawa, Takashi;
Tostar, Ulrica;
Jin, Qianren;
Fendrich, Volker;
Guerra, Carmen;
Barbacid, Mariano;
Toftgård, Rune

Publication type:

Article

Novel Variant of the Desert Hedgehog Gene in an Indian Patient of 46, XY Gonadal Dysgenesis with Peripheral Neuropathy.

Published in:

Neurology India, 2025, v. 73, n. 2, p. 352, doi. 10.4103/neurol-india.Neurol-India-D-24-00093

By:

Srivastava, Kosha;
Baskar, Dipti;
Vengalil, Seena;
Nashi, Saraswati;
Menon, Deepak;
Ganji, Suma R.;
Sanka, Sai B.;
Polavarapu, Kiran;
Rao, Bhoomika M;
Arunachal, Gautham;
Nalini, Atchayaram

Publication type:

Article

PDLIM3 knockdown promotes ferroptosis in endometriosis progression via inducing Gli1 degradation and blocking Hedgehog signaling pathway.

Published in:

Journal of Assisted Reproduction & Genetics, 2024, v. 41, n. 8, p. 2117, doi. 10.1007/s10815-024-03131-8

By:

Liu, Mingwei;
Wang, Xianxian;
Zhu, Jiannan

Publication type:

Article

Hedgehog signaling is activated in canine transitional cell carcinoma and contributes to cell proliferation and survival.

Published in:

Veterinary & Comparative Oncology, 2017, v. 15, n. 1, p. 174, doi. 10.1111/vco.12149

By:

Gustafson, T. L.;
Kitchell, B. E.;
Biller, B.

Publication type:

Article

Exploring the Potential of Anthraquinone‐Based Hybrids for Identifying a Novel Generation of Antagonists for the Smoothened Receptor in HH‐Dependent Tumour.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 62, p. 1, doi. 10.1002/chem.202302237

By:

Quaglio, Deborah;
Infante, Paola;
Cammarone, Silvia;
Lamelza, Lara;
Conenna, Marilisa;
Ghirga, Francesca;
Adabbo, Gennaro;
Pisano, Luca;
Di Marcotullio, Lucia;
Botta, Bruno;
Mori, Mattia

Publication type:

Article

Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 67, p. 1, doi. 10.1002/chem.202202164

By:

Grigalunas, Michael;
Patil, Sohan;
Krzyzanowski, Adrian;
Pahl, Axel;
Flegel, Jana;
Schölermann, Beate;
Xie, Jianing;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 32, p. 8350, doi. 10.1002/chem.202100315

By:

Bonandi, Elisa;
Mori, Mattia;
Infante, Paola;
Basili, Irene;
Di Marcotullio, Lucia;
Calcaterra, Andrea;
Catti, Federica;
Botta, Bruno;
Passarella, Daniele

Publication type:

Article

Harnessing the role of aberrant cell signaling pathways in glioblastoma multiforme: a prospect towards the targeted therapy.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09996-3

By:

Hasan, Subbrina;
Mahmud, Zimam;
Hossain, Mahmud;
Islam, Sohidul

Publication type:

Article

Harnessing the role of aberrant cell signaling pathways in glioblastoma multiforme: a prospect towards the targeted therapy.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09996-3

By:

Hasan, Subbrina;
Mahmud, Zimam;
Hossain, Mahmud;
Islam, Sohidul

Publication type:

Article

Sex and hedgehog: roles of genes in the hedgehog signaling pathway in mammalian sexual differentiation.

Published in:

Chromosome Research, 2012, v. 20, n. 1, p. 247, doi. 10.1007/s10577-011-9254-z

By:

Franco, Heather;
Yao, Humphrey

Publication type:

Article

Sonic hedgehog is a potent chemoattractant for human monocytes: diabetes mellitus inhibits Sonic hedgehog-induced monocyte chemotaxis.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 1, p. 61, doi. 10.1007/s00395-009-0047-x

By:

Dunaeva, Marina;
Voo, Stefan;
van Oosterhoud, Carolien;
Waltenberger, Johannes

Publication type:

Article

YY1-induced transcription of AKR1C3 activates the Hedgehog signalling pathway to enhance lenalidomide resistance and glycolytic activity in multiple myeloma cells.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01619-w

By:

Chen, Yang;
Zhang, Aijia;
Wang, Yuan;
Qi, Daoda;
Peng, Chengyi;
Liang, Zihao;
Guo, Jingjing;
Gu, Yan

Publication type:

Article

YY1-induced transcription of AKR1C3 activates the Hedgehog signalling pathway to enhance lenalidomide resistance and glycolytic activity in multiple myeloma cells.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01619-w

By:

Chen, Yang;
Zhang, Aijia;
Wang, Yuan;
Qi, Daoda;
Peng, Chengyi;
Liang, Zihao;
Guo, Jingjing;
Gu, Yan

Publication type:

Article

Serum Level of Desert Hedgehog Protein in Autism Spectrum Disorder: Preliminary Results.

Published in:

Medical Principles & Practice, 2013, v. 23, n. 1, p. 14, doi. 10.1159/000354295

By:

Bashir, Shahid;
Halepoto, Dost Muhammad;
Al-Ayadhi, Laila

Publication type:

Article

Clinical Characteristics of an Italian Patient Population with Advanced BCC and Real-Life Evaluation of Hedgehog Pathway Inhibitor Safety and Effectiveness.

Published in:

Dermatology (10188665), 2023, v. 239, n. 6, p. 868, doi. 10.1159/000531280

By:

Mannino, Maria;
Piccerillo, Alfredo;
Fabbrocini, Gabriella;
Quaglino, Pietro;
Argenziano, Giuseppe;
Dika, Emi;
Ascierto, Paolo Antonio;
Pellacani, Giovanni;
Longo, Caterina;
Fargnoli, Maria Concetta;
Bianchi, Luca;
Calzavara-Pinton, Piergiacomo;
Zalaudek, Iris;
Fava, Paolo;
Scalvenzi, Massimiliano;
Bocchino, Enrico;
Di Stefani, Alessandro;
Peris, Ketty

Publication type:

Article

Swiss Recommendations for Cutaneous Basal Cell Carcinoma.

Published in:

Dermatology (10188665), 2023, v. 239, n. 1, p. 122, doi. 10.1159/000526478

By:

Ramelyte, Egle;
Nägeli, Mirjam C.;
Hunger, Robert;
Merat, Rastine;
Gaide, Olivier;
Navarini, Alexander A.;
Cozzio, Antonio;
Wagner, Nikolaus B.;
Maul, Lara Valeska;
Dummer, Reinhard

Publication type:

Article

Vismodegib in Locally Advanced Basal Cell Carcinoma in Slovenia.

Published in:

Dermatology (10188665), 2023, v. 239, n. 1, p. 158, doi. 10.1159/000525612

By:

Mesti, Tanja;
Sever, Maša;
Ocvirk, Janja

Publication type:

Article

Another twist to the GLI code.

Published in:

Biochemical Journal, 2020, v. 477, n. 22, p. 4343, doi. 10.1042/BCJ20200617

By:

Timmis, Alex J.;
Galdo, Natalia A. Riobo-Del

Publication type:

Article

GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.

Published in:

Biochemical Journal, 2020, v. 477, n. 17, p. 3131, doi. 10.1042/BCJ20200335

By:

Tolosa, Ezequiel J.;
Fernandez-Barrena, Maite G.;
Iguchi, Eriko;
McCleary-Wheeler, Angela L.;
Carr, Ryan M.;
Almada, Luciana L.;
Flores, Luis F.;
Vera, Renzo E.;
Alfonse, Germine W.;
Marks, David L.;
Hogenson, Tara L.;
Vrabel, Anne M.;
Horn, Isaac P.;
Koenig, Amanda N.;
Safgren, Stephanie L.;
Sigafoos, Ashley N.;
Erkan, Mert;
Romecin-Duran, Paola A.;
Gonzalez, Alejandro Sarabia;
Bo Zhou

Publication type:

Article

The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02718-6

By:

de la Rocha-Muñoz, Andrés;
Núñez, Enrique;
Vishwanath, Anjali Amrapali;
Gómez-López, Sergio;
Dhanasobhon, Dhanasak;
Rebola, Nelson;
López-Corcuera, Beatriz;
de Juan-Sanz, Jaime;
Aragón, Carmen

Publication type:

Article

Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02567-3

By:

Malave, Lauren;
Zuelke, Dustin R.;
Uribe-Cano, Santiago;
Starikov, Lev;
Rebholz, Heike;
Friedman, Eitan;
Qin, Chuan;
Li, Qin;
Bezard, Erwan;
Kottmann, Andreas H.

Publication type:

Article

Neuroimmunology: a CNS guard as prickly as a hedgehog.

Published in:

2012

By:

Papatriantafyllou, Maria

Publication type:

journal article

THE POWER OF GENETIC RESEARCH: UNDERSTANDING THE ROLE OF RAB23 GENE IN CARPENTER SYNDROME.

Published in:

Genetics & Applications, 2023, p. 60

By:

Selma, Muratović

Publication type:

Article

Formulation and evaluation of itraconazole liposomes for Hedgehog pathway inhibition.

Published in:

Journal of Liposome Research, 2020, v. 30, n. 3, p. 305, doi. 10.1080/08982104.2019.1668011

By:

Pace, Jennifer R.;
Jog, Rajan;
Burgess, Diane J.;
Hadden, M. Kyle

Publication type:

Article

Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 12, p. 1872, doi. 10.1002/jat.4520

By:

Silva, Camila S.;
Kudlyk, Tetyana;
Tryndyak, Volodymyr P.;
Twaddle, Nathan C.;
Robinson, Bonnie;
Gu, Qiang;
Beland, Frederick A.;
Fitzpatrick, Suzanne C.;
Kanungo, Jyotshna

Publication type:

Article

Emerging roles of the Hedgehog signalling pathway in inflammatory bowel disease.

Published in:

Cell Death Discovery, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41420-021-00679-7

By:

Xie, Zhuo;
Zhang, Mudan;
Zhou, Gaoshi;
Lin, Lihui;
Han, Jing;
Wang, Ying;
Li, Li;
He, Yao;
Zeng, Zhirong;
Chen, Minhu;
Zhang, Shenghong

Publication type:

Article

Development and validation of an RBP gene signature for prognosis prediction in colorectal cancer based on WGCNA.

Published in:

Hereditas, 2023, v. 160, n. 1, p. 1, doi. 10.1186/s41065-023-00274-z

By:

Cao, Lu;
Duan, Lili;
Zhang, Rui;
Yang, Wanli;
Yang, Ning;
Huang, Wenzhe;
Chen, Xuemin;
Wang, Nan;
Niu, Liaoran;
Zhou, Wei;
Chen, Junfeng;
Li, Yiding;
Zhang, Yujie;
Liu, Jinqiang;
Fan, Daiming;
Liu, Hong

Publication type:

Article

Structural insight into Class F receptors – What have we learnt regarding agonist‐induced activation?

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 126, p. 17, doi. 10.1111/bcpt.13235

By:

Schulte, Gunnar;
Kozielewicz, Paweł

Publication type:

Article

Wound Healing Effect of Supercritical Carbon Dioxide Datura metel L. Leaves Extracts: An In Vitro Study of Anti-Inflammation, Cell Migration, MMP-2 Inhibition, and the Modulation of the Sonic Hedgehog Pathway in Human Fibroblasts.

Published in:

Plants (2223-7747), 2023, v. 12, n. 13, p. 2546, doi. 10.3390/plants12132546

By:

Ruksiriwanich, Warintorn;
Linsaenkart, Pichchapa;
Muangsanguan, Anurak;
Sringarm, Korawan;
Jantrawut, Pensak;
Arjin, Chaiwat;
Sommano, Sarana Rose;
Phimolsiripol, Yuthana;
Barba, Francisco J.

Publication type:

Article

p53 and RB1 regulate Hedgehog responsiveness via autophagy-mediated ciliogenesis.

Published in:

Molecular & Cellular Oncology, 2020, v. 7, n. 6, p. 1, doi. 10.1080/23723556.2020.1805095

By:

Cain, Jason E.;
Watkins, D. Neil

Publication type:

Article

Partial duplication of DHH causes minifascicular neuropathy.

Published in:

Annals of Clinical & Translational Neurology, 2017, v. 4, n. 6, p. 415, doi. 10.1002/acn3.417

By:

Sato, Naoko Saito;
Maekawa, Risa;
Ishiura, Hiroyuki;
Mitsui, Jun;
Naruse, Hiroya;
Tokushige, Shin‐ichi;
Sugie, Kazuma;
Tate, Genshu;
Shimizu, Jun;
Goto, Jun;
Tsuji, Shoji;
Shiio, Yasushi

Publication type:

Article

Somatic mutations in GLI3 and OFD1 involved in sonic hedgehog signaling cause hypothalamic hamartoma.

Published in:

Annals of Clinical & Translational Neurology, 2016, v. 3, n. 5, p. 356, doi. 10.1002/acn3.300

By:

Saitsu, Hirotomo;
Sonoda, Masaki;
Higashijima, Takefumi;
Shirozu, Hiroshi;
Masuda, Hiroshi;
Tohyama, Jun;
Kato, Mitsuhiro;
Nakashima, Mitsuko;
Tsurusaki, Yoshinori;
Mizuguchi, Takeshi;
Miyatake, Satoko;
Miyake, Noriko;
Kameyama, Shigeki;
Matsumoto, Naomichi

Publication type:

Article

Astragalus polysaccharide ameliorates diabetic retinopathy by inhibiting the SHH-Gli1-AQP1 signaling pathway in streptozotocin-induced type 2 diabetic rats.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 1, p. 21, doi. 10.4196/kjpp.23.251

By:

Jingrong Qu;
Bo Wang;
Yulong Wang;
Hao Li;
Xiaomei An

Publication type:

Article

PTCH1 mutant small cell glioblastoma in a patient with Gorlin syndrome: A case report.

Published in:

Oncology Letters, 2022, v. 24, n. 3, p. N.PAG, doi. 10.3892/ol.2022.13446

By:

Dorsey, John T.;
Mott, Ryan T.;
Lack, Christopher M.;
Britt, Nicholas;
Ramkissoon, Shakti H.;
Morris, Bonny B.;
Carter, Annette;
Detroye, Alisha T.;
Chan, Michael;
Tatter, Stephen;
Lesser, Glenn J.

Publication type:

Article

Hedgehog signaling regulates the development and treatment of glioblastoma.

Published in:

Oncology Letters, 2022, v. 24, n. 3, p. N.PAG, doi. 10.3892/ol.2022.13414

By:

Wang, Hongping;
Lai, Qun;
Wang, Dayong;
Pei, Jian;
Tian, Baogang;
Gao, Yunhe;
Gao, Zhaoguo;
Xu, Xiang

Publication type:

Article

Expression of the Sonic Hedgehog pathway components in clear cell renal cell carcinoma.

Published in:

Oncology Letters, 2019, v. 18, n. 6, p. 5801, doi. 10.3892/ol.2019.10919

By:

Kotulak-Chrzaszcz, Anna;
Klacz, Jakub;
Matuszewski, Marcin;
Kmiec, Zbigniew;
Wierzbicki, Piotr M.

Publication type:

Article

Expression of Smo in pancreatic cancer CD44<sup>+</sup>CD24<sup>+</sup>cells and construction of a lentiviral expression vector to silence Smo.

Published in:

Oncology Letters, 2018, v. 16, n. 4, p. 4855, doi. 10.3892/ol.2018.9315

By:

Cong, Peng;
Yi, Chao;
Wang, Xi-Yan

Publication type:

Article