Works matching DE "HEDGEHOG genetics"
Results: 53
Identification of sonic hedgehog-regulated genes and biological processes in the cranial neural crest mesenchyme by comparative transcriptomics.
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- BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-4885-5
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- Article
Stem cell signaling as a target for novel drug discovery: recent progress in the WNT and Hedgehog pathways.
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- Acta Pharmacologica Sinica, 2013, v. 34, n. 6, p. 777, doi. 10.1038/aps.2013.64
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Occurrence and molecular characterization of Cryptosporidium spp. genotypes in European hedgehogs (Erinaceus europaeus L.) in Germany.
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- Parasitology, 2010, v. 137, n. 2, p. 205, doi. 10.1017/S0031182009991089
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- Article
Sonic hedgehog-c-Jun N-terminal kinase-zinc finger protein Gli1 signaling protects against high glucose concentration-induced reactive oxygen species generation in human fibroblasts.
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- Experimental & Therapeutic Medicine, 2018, v. 15, n. 6, p. 5084, doi. 10.3892/etm.2018.6074
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Genetic variants in HHIP are associated with FEV<sub>1</sub> in subjects with chronic obstructive pulmonary disease.
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- Respirology, 2013, v. 18, n. 8, p. 1202, doi. 10.1111/resp.12139
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- Article
Sonic hedgehog-dependent activation of adventitial fibroblasts promotes neointima formation.
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- Cardiovascular Research, 2017, v. 113, n. 13, p. 1653, doi. 10.1093/cvr/cvx158
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- Article
Radial glial elements in the cerebral cortex of the lesser hedgehog tenrec.
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- Brain Structure & Function, 2018, v. 223, n. 9, p. 3909, doi. 10.1007/s00429-018-1730-1
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Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis.
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- Cell Research, 2013, v. 23, n. 4, p. 573, doi. 10.1038/cr.2013.29
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Exon array analysis reveals genetic heterogeneity in atypical femoral fractures. A pilot study.
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- Molecular & Cellular Biochemistry, 2015, v. 409, n. 1/2, p. 45, doi. 10.1007/s11010-015-2510-3
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Mkx‐Deficient Mice Exhibit Hedgehog Signaling–Dependent Ectopic Ossification in the Achilles Tendons.
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- Journal of Bone & Mineral Research, 2019, v. 34, n. 3, p. 557, doi. 10.1002/jbmr.3630
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Disruption of Scube2 Impairs Endochondral Bone Formation.
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- Journal of Bone & Mineral Research, 2015, v. 30, n. 7, p. 1255, doi. 10.1002/jbmr.2451
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The hedgehog pathway in nonalcoholic fatty liver disease.
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- Critical Reviews in Biochemistry & Molecular Biology, 2018, v. 53, n. 3, p. 264, doi. 10.1080/10409238.2018.1448752
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Cytoneme-Mediated Delivery of Hedgehog Regulates the Expression of Bone Morphogenetic Proteins to Maintain Germline Stem Cells in Drosophila.
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- PLoS Biology, 2012, v. 10, n. 4, p. 1, doi. 10.1371/journal.pbio.1001298
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The Hedgehog Signaling Pathway: Where Did It Come From?
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- PLoS Biology, 2009, v. 7, n. 6, p. 1, doi. 10.1371/journal.pbio.1000146
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- Article
Apaf1 apoptotic function critically limits Sonic hedgehog signaling during craniofacial development.
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- Cell Death & Differentiation, 2013, v. 20, n. 11, p. 1510, doi. 10.1038/cdd.2013.97
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Formation and subdivision of the head field in the centipede Strigamia maritima, as revealed by the expression of head gap gene orthologues and hedgehog dynamics.
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- EvoDevo, 2017, v. 8, p. 1, doi. 10.1186/s13227-017-0082-x
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Limb patterning genes and heterochronic development of the emu wing bud.
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- EvoDevo, 2016, v. 7, p. 1, doi. 10.1186/s13227-016-0063-5
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In Vitro and Molecular Modeling Analysis of Two Mutant Desert Hedgehog Proteins Associated with 46,XY Gonadal Dysgenesis.
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- DNA & Cell Biology, 2013, v. 32, n. 9, p. 524, doi. 10.1089/dna.2013.2052
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- Article
Cell-Sorting at the A/P Boundary in the Drosophila Wing Primordium: A Computational Model to Consolidate Observed Non-Local Effects of Hh Signaling.
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- PLoS Computational Biology, 2011, v. 7, n. 4, p. 1, doi. 10.1371/journal.pcbi.1002025
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Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.
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- Cell & Tissue Research, 2017, v. 370, n. 2, p. 211, doi. 10.1007/s00441-017-2664-2
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- Article
Inhibition of Gli1 results in altered c-Jun activation, inhibition of cisplatin-induced upregulation of ERCC1, XPD and XRCC1, and inhibition of platinum-DNA adduct repair.
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- Oncogene, 2012, v. 31, n. 44, p. 4718, doi. 10.1038/onc.2011.610
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Intrafamilial variability of ZRS-associated syndrome: characterization of a mosaic ZRS mutation by pyrosequencing.
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- Clinical Genetics, 2015, v. 88, n. 5, p. 479, doi. 10.1111/cge.12534
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- Article
TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.
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- Acta Neuropathologica, 2019, v. 137, n. 4, p. 657, doi. 10.1007/s00401-019-01982-5
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Mutational analysis of selected genes encoding canonical and non-canonical SHH signaling pathway in pediatric germ cell tumors.
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- European Journal of Translational & Clinical Medicine, 2021, v. 4, p. 75
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- Article
Sonic Hedgehog Expands Diaphyseal Trabecular Bone Altering Bone Marrow Niche and Lymphocyte Compartment.
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- Molecular Therapy, 2009, v. 17, n. 8, p. 1442, doi. 10.1038/mt.2009.102
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- Article
Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epithelium.
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- IUBMB Life, 2014, v. 66, n. 10, p. 694, doi. 10.1002/iub.1319
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Novel Familial Variant of the Desert Hedgehog Gene: Clinical Findings in Two Sisters with 46,XY Gonadal Dysgenesis or 46,XX Karyotype and Literature Review.
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- Hormone Research in Paediatrics, 2018, v. 89, n. 3, p. 141, doi. 10.1159/000485507
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Multi-layered mutation in hedgehog-related genes in Gorlin syndrome may affect the phenotype.
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- PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184702
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Positive regulatory interactions between YAP and Hedgehog signalling in skin homeostasis and BCC development in mouse skin in vivo.
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- PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183178
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Expression of hedgehog signaling molecules as a prognostic indicator of oral squamous cell carcinoma.
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- Head & Neck, 2012, v. 34, n. 11, p. 1556, doi. 10.1002/hed.21958
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- Article
Hepatoprotective Effect of Kombucha Tea in Rodent Model of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2369, doi. 10.3390/ijms20092369
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- Article
Sonic Hedgehog Signaling Is Required for Cyp26 Expression during Embryonic Development.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2275, doi. 10.3390/ijms20092275
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- Article
A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.
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- PLoS Genetics, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pgen.1006951
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Synthesis and Smo Activity of Some Novel Benzamide Derivatives.
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- Molecules, 2018, v. 23, n. 1, p. 85, doi. 10.3390/molecules23010085
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Vismodegib.
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- Nature Reviews Drug Discovery, 2012, v. 11, n. 6, p. 437, doi. 10.1038/nrd3753
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Liver kinase B1 suppresses growth of lung cancer cells through sonic hedgehog signaling pathway.
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- Cell Biology International, 2018, v. 42, n. 8, p. 994, doi. 10.1002/cbin.10965
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- Article
Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate.
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- Nature Cell Biology, 2014, v. 16, n. 12, p. 1135, doi. 10.1038/ncb3057
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- Article
Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate.
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- Nature Genetics, 2012, v. 44, n. 3, p. 348, doi. 10.1038/ng.1090
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- Article
Molecular evidence supports recent anthropogenic introduction of the Algerian hedgehog Atelerix algirus in Spain, Balearic and Canary islands from North Africa.
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- Mammalia: International Journal of the Systematics, Biology & Ecology of Mammals, 2016, v. 80, n. 3, p. 313, doi. 10.1515/mammalia-2014-0180
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- Article
Cytoneme-mediated cell-cell contacts for Hedgehog reception.
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- eLife, 2017, p. 1, doi. 10.7554/eLife.24045.001
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Hedgehog interacting protein (HHIP) represses airway remodeling and metabolic reprogramming in COPD-derived airway smooth muscle cells.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88434-x
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- Article
Gene cloning, expression and functional characterization of a proliferation-inducing ligand (APRIL) from hedgehog ( Erinaceus europaeus).
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- Molecular Biology Reports, 2012, v. 39, n. 5, p. 6123, doi. 10.1007/s11033-011-1428-4
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- Article
Prenatal identification of two discontinuous maternally inherited chromosome 7q36.3 microduplications totaling 507 kb including the sonic hedgehog gene in a fetus with multiple congenital anomalies.
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- Clinical Case Reports, 2017, v. 5, n. 6, p. 993, doi. 10.1002/ccr3.982
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- Article
Knockdown of Indian hedgehog protein induces an inhibition of cell growth and differentiation in osteoblast MC3T3-E1 cells.
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- Molecular Medicine Reports, 2017, v. 16, n. 6, p. 7987, doi. 10.3892/mmr.2017.7669
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Hedgehog gene polymorphisms are associated with the risk of Hirschsprung's disease and anorectal malformation in a Chinese population.
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- Molecular Medicine Reports, 2016, v. 13, n. 6, p. 4759, doi. 10.3892/mmr.2016.5139
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Molecular Dynamics Simulations of Sonic Hedgehog-Receptor and Inhibitor Complexes and Their Applications for Potential Anticancer Agent Discovery.
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- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068271
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- Article
Mutations in the Hedgehog Pathway Genes SMO and PTCH1 in Human Gastric Tumors.
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- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054415
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- Article
A Novel Signaling Pathway Mediated by the Nuclear Targeting of C-Terminal Fragments of Mammalian Patched 1.
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- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018638
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Hedgehog Inhibition Promotes a Switch from Type II to Type I Cell Death Receptor Signaling in Cancer Cells.
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- PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018330
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- Article
Two Lamprey Hedgehog Genes Share Non-Coding Regulatory Sequences and Expression Patterns with Gnathostome Hedgehogs.
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- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013332
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