Works matching DE "HEDGEHOG genetics"

Results: 53

Cytoneme-Mediated Delivery of Hedgehog Regulates the Expression of Bone Morphogenetic Proteins to Maintain Germline Stem Cells in Drosophila.

Published in:

PLoS Biology, 2012, v. 10, n. 4, p. 1, doi. 10.1371/journal.pbio.1001298

By:

Rojas-Ríos, Patricia;
Guerrero, Isabel;
González-Reyes, Acaimo

Publication type:

Article

The Hedgehog Signaling Pathway: Where Did It Come From?

Published in:

PLoS Biology, 2009, v. 7, n. 6, p. 1, doi. 10.1371/journal.pbio.1000146

By:

Hausmann, George;
von Mering, Christian;
Basler, Konrad

Publication type:

Article

Mkx‐Deficient Mice Exhibit Hedgehog Signaling–Dependent Ectopic Ossification in the Achilles Tendons.

Published in:

Journal of Bone & Mineral Research, 2019, v. 34, n. 3, p. 557, doi. 10.1002/jbmr.3630

By:

Liu, Han;
Xu, Jingyue;
Jiang, Rulang

Publication type:

Article

Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis.

Published in:

Cell Research, 2013, v. 23, n. 4, p. 573, doi. 10.1038/cr.2013.29

By:

Zhang, Zhao;
Lv, Xiangdong;
Jiang, Jin;
Zhang, Lei;
Zhao, Yun

Publication type:

Article

Synthesis and Smo Activity of Some Novel Benzamide Derivatives.

Published in:

Molecules, 2018, v. 23, n. 1, p. 85, doi. 10.3390/molecules23010085

By:

Ding, Huaiwei;
Chen, Kai;
Song, Bingke;
Deng, Chenglong;
Li, Wei;
Niu, Li;
Bai, Mengxuan;
Song, Hongrui;
Zhang, Lijuan

Publication type:

Article

TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.

Published in:

Acta Neuropathologica, 2019, v. 137, n. 4, p. 657, doi. 10.1007/s00401-019-01982-5

By:

Hellwig, Malte;
Holdhof, Dörthe;
Niesen, Judith;
Schoof, Melanie;
Schüller, Ulrich;
Bockmayr, Michael;
Kool, Marcel;
Kraus, Cornelia;
Zweier, Christiane;
Holmberg, Dan;
Spohn, Michael;
Ahlfeld, Julia;
Kitowski, Annabel;
Ohli, Jasmin;
Lauffer, Marlen C.;
Merk, Daniel J.;
Harrison, Luke;
Neumann, Julia E.

Publication type:

Article

Hedgehog interacting protein (HHIP) represses airway remodeling and metabolic reprogramming in COPD-derived airway smooth muscle cells.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88434-x

By:

Li, Yan;
Zhang, Li;
Polverino, Francesca;
Guo, Feng;
Hao, Yuan;
Lao, Taotao;
Xu, Shuang;
Li, Lijia;
Pham, Betty;
Owen, Caroline A.;
Zhou, Xiaobo

Publication type:

Article

Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate.

Published in:

Nature Cell Biology, 2014, v. 16, n. 12, p. 1135, doi. 10.1038/ncb3057

By:

Lim, Agnes;
Shin, Kunyoo;
Zhao, Chen;
Kawano, Sally;
Beachy, Philip A.

Publication type:

Article

Cell-Sorting at the A/P Boundary in the Drosophila Wing Primordium: A Computational Model to Consolidate Observed Non-Local Effects of Hh Signaling.

Published in:

PLoS Computational Biology, 2011, v. 7, n. 4, p. 1, doi. 10.1371/journal.pcbi.1002025

By:

Schilling, Sabine;
Willecke, Maria;
Aegerter-Wilmsen, Tinri;
Cirpka, Olaf A.;
Basler, Konrad;
von Mering, Christian

Publication type:

Article

Occurrence and molecular characterization of Cryptosporidium spp. genotypes in European hedgehogs (Erinaceus europaeus L.) in Germany.

Published in:

Parasitology, 2010, v. 137, n. 2, p. 205, doi. 10.1017/S0031182009991089

By:

Dyachenko, V.;
Kuhnert, Y.;
Schmaeschke, R.;
Etzold, M.;
Pantchev, N.;
Daugschies, A.

Publication type:

Article

Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epithelium.

Published in:

IUBMB Life, 2014, v. 66, n. 10, p. 694, doi. 10.1002/iub.1319

By:

Xu, Changxin;
Li, Xiufen;
Topham, Matthew K.;
Kuwada, Scott K.

Publication type:

Article

Expression of hedgehog signaling molecules as a prognostic indicator of oral squamous cell carcinoma.

Published in:

Head & Neck, 2012, v. 34, n. 11, p. 1556, doi. 10.1002/hed.21958

By:

Wang, Yi-Fen;
Chang, Chun-Ju;
Lin, Chin-Ping;
Chang, Shyue-Yih;
Chu, Pen-Yuan;
Tai, Shyh-Kuan;
Li, Wing-Yin;
Chao, K.S. Clifford;
Chen, Yu-Jen

Publication type:

Article

Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid-Inspired Compound Collection.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 47, p. 12404, doi. 10.1002/anie.201306948

By:

Takayama, Hiroshi;
Jia, Zhi‐Jun;
Kremer, Lea;
Bauer, Jonathan O.;
Strohmann, Carsten;
Ziegler, Slava;
Antonchick, Andrey P.;
Waldmann, Herbert

Publication type:

Article

Radial glial elements in the cerebral cortex of the lesser hedgehog tenrec.

Published in:

Brain Structure & Function, 2018, v. 223, n. 9, p. 3909, doi. 10.1007/s00429-018-1730-1

By:

Mack, Andreas F.;
Künzle, Heinz;
Lange, Mario;
Mages, Bianca;
Reichenbach, Andreas;
Härtig, Wolfgang

Publication type:

Article

Identification of sonic hedgehog-regulated genes and biological processes in the cranial neural crest mesenchyme by comparative transcriptomics.

Published in:

BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-4885-5

By:

Everson, Joshua L.;
Fink, Dustin M.;
Chung, Hannah M.;
Sun, Miranda R.;
Lipinski, Robert J.

Publication type:

Article

Stem cell signaling as a target for novel drug discovery: recent progress in the WNT and Hedgehog pathways.

Published in:

Acta Pharmacologica Sinica, 2013, v. 34, n. 6, p. 777, doi. 10.1038/aps.2013.64

By:

An, Songzhu Michael;
Ding, Qiang Peter;
Li, Ling-song

Publication type:

Article

Gene cloning, expression and functional characterization of a proliferation-inducing ligand (APRIL) from hedgehog ( Erinaceus europaeus).

Published in:

Molecular Biology Reports, 2012, v. 39, n. 5, p. 6123, doi. 10.1007/s11033-011-1428-4

By:

Cui, Xian-wei;
Xiao, Wen;
Ji, Chen-bo;
Tian, Ai-ying;
Zhang, Jie;
Zhang, Shuang-quan

Publication type:

Article

Liver kinase B1 suppresses growth of lung cancer cells through sonic hedgehog signaling pathway.

Published in:

Cell Biology International, 2018, v. 42, n. 8, p. 994, doi. 10.1002/cbin.10965

By:

Song, Kuiyuan;
Zheng, Guanqun;
Zhao, Yue

Publication type:

Article

Single-Cell Transcriptomics of the Human Endocrine Pancreas.

Published in:

2016

By:

Wang, Yue J.;
Jonathan Schug;
Kyoung-Jae Won;
Chengyang Liu;
Ali Naji;
Dana Avrahami;
Golson, Maria L.;
Kaestner, Klaus H.;
Schug, Jonathan;
Won, Kyoung-Jae;
Liu, Chengyang;
Naji, Ali;
Avrahami, Dana

Publication type:

journal article

A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.

Published in:

PLoS Genetics, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pgen.1006951

By:

Bohnenpoll, Tobias;
Wittern, Anna B.;
Mamo, Tamrat M.;
Weiss, Anna-Carina;
Rudat, Carsten;
Kleppa, Marc-Jens;
Schuster-Gossler, Karin;
Wojahn, Irina;
Lüdtke, Timo H.-W.;
Trowe, Mark-Oliver;
Kispert, Andreas

Publication type:

Article

Vismodegib.

Published in:

Nature Reviews Drug Discovery, 2012, v. 11, n. 6, p. 437, doi. 10.1038/nrd3753

By:

Dlugosz, Andrzej;
Agrawal, Sid;
Kirkpatrick, Peter

Publication type:

Article

Multi-layered mutation in hedgehog-related genes in Gorlin syndrome may affect the phenotype.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184702

By:

Onodera, Shoko;
Saito, Akiko;
Hasegawa, Daigo;
Morita, Nana;
Watanabe, Katsuhito;
Nomura, Takeshi;
Shibahara, Takahiko;
Ohba, Shinsuke;
Yamaguchi, Akira;
Azuma, Toshifumi

Publication type:

Article

Positive regulatory interactions between YAP and Hedgehog signalling in skin homeostasis and BCC development in mouse skin in vivo.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183178

By:

Akladios, Bassem;
Mendoza Reinoso, Veronica;
Cain, Jason E.;
Wang, Taopeng;
Lambie, Duncan L.;
Watkins, D. Neil;
Beverdam, Annemiek

Publication type:

Article

Sonic hedgehog-dependent activation of adventitial fibroblasts promotes neointima formation.

Published in:

Cardiovascular Research, 2017, v. 113, n. 13, p. 1653, doi. 10.1093/cvr/cvx158

By:

Dutzmann, Jochen;
Koch, Alexander;
Weisheit, Simona;
Sonnenschein, Kristina;
Korte, Laura;
Haertlé, Marco;
Thum, Thomas;
Bauersachs, Johann;
Sedding, Daniel G.;
Daniel, Jan-Marcus

Publication type:

Article

In Vitro and Molecular Modeling Analysis of Two Mutant Desert Hedgehog Proteins Associated with 46,XY Gonadal Dysgenesis.

Published in:

DNA & Cell Biology, 2013, v. 32, n. 9, p. 524, doi. 10.1089/dna.2013.2052

By:

Castro, Josué Joram;
Méndez, Juan Pablo;
Coral-Vázquez, Ramón Mauricio;
Soriano-Ursúa, Marvin Antonio;
Damian-Matsumura, Pablo;
Benítez-Granados, Jesús;
Rosas-Vargas, Haydee;
Canto, Patricia

Publication type:

Article

Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.

Published in:

Cell & Tissue Research, 2017, v. 370, n. 2, p. 211, doi. 10.1007/s00441-017-2664-2

By:

Feuerstein, Melanie;
Chleilat, Enaam;
Khakipoor, Shokoufeh;
Michailidis, Konstantinos;
Ophoven, Christian;
Roussa, Eleni

Publication type:

Article

Prenatal identification of two discontinuous maternally inherited chromosome 7q36.3 microduplications totaling 507 kb including the sonic hedgehog gene in a fetus with multiple congenital anomalies.

Published in:

Clinical Case Reports, 2017, v. 5, n. 6, p. 993, doi. 10.1002/ccr3.982

By:

Micale, Mark;
Embrey, Bedford;
Hubbell, Katie;
Beaudry‐Rogers, Kelly;
Whitten, Amy

Publication type:

Article

Hepatoprotective Effect of Kombucha Tea in Rodent Model of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2369, doi. 10.3390/ijms20092369

By:

Lee, Chanbin;
Kim, Jieun;
Wang, Sihyung;
Sung, Sumi;
Kim, Namgyu;
Lee, Hyun-Hee;
Seo, Young-Su;
Jung, Youngmi

Publication type:

Article

Sonic Hedgehog Signaling Is Required for Cyp26 Expression during Embryonic Development.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2275, doi. 10.3390/ijms20092275

By:

El Shahawy, Maha;
Reibring, Claes-Göran;
Hallberg, Kristina;
Neben, Cynthia L.;
Marangoni, Pauline;
Harfe, Brian D.;
Klein, Ophir D.;
Linde, Anders;
Gritli-Linde, Amel

Publication type:

Article

Formation and subdivision of the head field in the centipede Strigamia maritima, as revealed by the expression of head gap gene orthologues and hedgehog dynamics.

Published in:

EvoDevo, 2017, v. 8, p. 1, doi. 10.1186/s13227-017-0082-x

By:

Hunnekuhl, Vera S.;
Akam, Michael

Publication type:

Article

Limb patterning genes and heterochronic development of the emu wing bud.

Published in:

EvoDevo, 2016, v. 7, p. 1, doi. 10.1186/s13227-016-0063-5

By:

Smith, Craig A.;
Farlie, Peter G.;
Davidson, Nadia M.;
Roeszler, Kelly N.;
Hirst, Claire;
Oshlack, Alicia;
Lambert, David M.

Publication type:

Article

Molecular evidence supports recent anthropogenic introduction of the Algerian hedgehog Atelerix algirus in Spain, Balearic and Canary islands from North Africa.

Published in:

Mammalia: International Journal of the Systematics, Biology & Ecology of Mammals, 2016, v. 80, n. 3, p. 313, doi. 10.1515/mammalia-2014-0180

By:

Khaldi, Mourad;
Ribas, Alexis;
Barech, Ghania;
Hugot, Jean-Pierre;
Benyettou, Meryam;
Albane, Lila;
Arrizabalaga, Antoni;
Nicolas, Violaine

Publication type:

Article

Disruption of Scube2 Impairs Endochondral Bone Formation.

Published in:

Journal of Bone & Mineral Research, 2015, v. 30, n. 7, p. 1255, doi. 10.1002/jbmr.2451

By:

Lin, Yuh-Charn;
Roffler, Steve R.;
Yan, Yu-Ting;
Yang, Ruey-Bing

Publication type:

Article

Inhibition of Gli1 results in altered c-Jun activation, inhibition of cisplatin-induced upregulation of ERCC1, XPD and XRCC1, and inhibition of platinum-DNA adduct repair.

Published in:

Oncogene, 2012, v. 31, n. 44, p. 4718, doi. 10.1038/onc.2011.610

By:

Kudo, K;
Gavin, E;
Das, S;
Amable, L;
Shevde, L A;
Reed, E

Publication type:

Article

Intrafamilial variability of ZRS-associated syndrome: characterization of a mosaic ZRS mutation by pyrosequencing.

Published in:

Clinical Genetics, 2015, v. 88, n. 5, p. 479, doi. 10.1111/cge.12534

By:

Vanlerberghe, C.;
Faivre, L.;
Petit, F.;
Fruchart, O.;
Jourdain, A.‐S.;
Clavier, F.;
Gay, S.;
Manouvrier‐Hanu, S.;
Escande, F.

Publication type:

Article

Molecular Dynamics Simulations of Sonic Hedgehog-Receptor and Inhibitor Complexes and Their Applications for Potential Anticancer Agent Discovery.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068271

By:

Hwang, Swan;
Thangapandian, Sundarapandian;
Lee, Keun Woo

Publication type:

Article

Mutations in the Hedgehog Pathway Genes SMO and PTCH1 in Human Gastric Tumors.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054415

By:

Xi-De Wang;
Inzunza, Hector;
Han Chang;
Zhenhao Qi;
Beihong Hu;
Malone, Daniel;
Cogswell, John

Publication type:

Article

A Novel Signaling Pathway Mediated by the Nuclear Targeting of C-Terminal Fragments of Mammalian Patched 1.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018638

By:

Kagawa, Hiroki;
Shino, Yuka;
Kobayashi, Daigo;
Demizu, Syunsuke;
Shimada, Masumi;
Ariga, Hiroyoshi;
Kawahara, Hiroyuki

Publication type:

Article

Hedgehog Inhibition Promotes a Switch from Type II to Type I Cell Death Receptor Signaling in Cancer Cells.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018330

By:

Kurita, Satoshi;
Mott, Justin L.;
Cazanave, Sophie C.;
Fingas, Christian D.;
Guicciardi, Maria E.;
Bronk, Steve F.;
Roberts, Lewis R.;
Fernandez-Zapico, Martin E.;
Gores, Gregory J.

Publication type:

Article

Two Lamprey Hedgehog Genes Share Non-Coding Regulatory Sequences and Expression Patterns with Gnathostome Hedgehogs.

Published in:

PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013332

By:

Shungo Kano;
Jin-Hua Xiao;
Osório, Joana;
Ekker, Marc;
Hadzhiev, Yavor;
Müller, Ferenc;
Casane, Didier;
Magdelenat, Ghislaine;
Rétaux, Sylvie

Publication type:

Article

Cytoneme-mediated cell-cell contacts for Hedgehog reception.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.24045.001

By:

González-Méndez, Laura;
Seijo-Barandiarán, Irene;
Guerrero, Isabel

Publication type:

Article

Novel Familial Variant of the Desert Hedgehog Gene: Clinical Findings in Two Sisters with 46,XY Gonadal Dysgenesis or 46,XX Karyotype and Literature Review.

Published in:

Hormone Research in Paediatrics, 2018, v. 89, n. 3, p. 141, doi. 10.1159/000485507

By:

Baldinotti, Fulvia;
Cavallaro, Tiziana;
Dati, Eleonora;
Baroncelli, Giampiero I.;
Bertini, Veronica;
Valetto, Angelo;
Massart, Francesco;
Fabrizi, Gian Maria;
Zanette, Giampietro;
Peroni, Diego;
Bertelloni, Silvano

Publication type:

Article

Knockdown of Indian hedgehog protein induces an inhibition of cell growth and differentiation in osteoblast MC3T3-E1 cells.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 6, p. 7987, doi. 10.3892/mmr.2017.7669

By:

ANG DENG;
HONGQI ZHANG;
MINYU HU;
SHAOHUA LIU;
QILE GAO;
YUXIANG WANG;
CHAOFENG GUO

Publication type:

Article

Hedgehog gene polymorphisms are associated with the risk of Hirschsprung's disease and anorectal malformation in a Chinese population.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 6, p. 4759, doi. 10.3892/mmr.2016.5139

By:

HONG GAO;
DAJIA WANG;
YUZUO BAI;
JUAN ZHANG;
MEI WU;
JIE MI;
HUIMIN JIA;
WEILIN WANG

Publication type:

Article

Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate.

Published in:

Nature Genetics, 2012, v. 44, n. 3, p. 348, doi. 10.1038/ng.1090

By:

Economou, Andrew D;
Ohazama, Atsushi;
Porntaveetus, Thantrira;
Sharpe, Paul T;
Kondo, Shigeru;
Basson, M Albert;
Gritli-Linde, Amel;
Cobourne, Martyn T;
Green, Jeremy B A

Publication type:

Article

Influenza NS1 directly modulates Hedgehog signaling during infection.

Published in:

PLoS Pathogens, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.ppat.1006588

By:

Smelkinson, Margery G.;
Guichard, Annabel;
Teijaro, John R.;
Malur, Meghana;
Loureiro, Maria Eugenia;
Jain, Prashant;
Ganesan, Sundar;
Zúñiga, Elina I.;
Krug, Robert M.;
Oldstone, Michael B.;
Bier, Ethan

Publication type:

Article

Exon array analysis reveals genetic heterogeneity in atypical femoral fractures. A pilot study.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 409, n. 1/2, p. 45, doi. 10.1007/s11010-015-2510-3

By:

Pérez-Núñez, Isabel;
Pérez-Castrillón, José;
Zarrabeitia, María;
García-Ibarbia, Carmen;
Martínez-Calvo, Laura;
Olmos, José;
Briongos, Laisa;
Riancho, Javier;
Camarero, Victoria;
Muñoz Vives, Josep;
Cruz, Raquel;
Riancho, José

Publication type:

Article

Mutational analysis of selected genes encoding canonical and non-canonical SHH signaling pathway in pediatric germ cell tumors.

Published in:

European Journal of Translational & Clinical Medicine, 2021, v. 4, p. 75

By:

Czarnota, Katarzyna

Publication type:

Article

Sonic Hedgehog Expands Diaphyseal Trabecular Bone Altering Bone Marrow Niche and Lymphocyte Compartment.

Published in:

Molecular Therapy, 2009, v. 17, n. 8, p. 1442, doi. 10.1038/mt.2009.102

By:

Kiuru, Maija;
Hidaka, Chisa;
Hubner, Ralf-Harto;
Solomon, Jason;
Krause, Anja;
Leopold, Philip L.;
Crystal, Ronald G.

Publication type:

Article

Sonic hedgehog-c-Jun N-terminal kinase-zinc finger protein Gli1 signaling protects against high glucose concentration-induced reactive oxygen species generation in human fibroblasts.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 6, p. 5084, doi. 10.3892/etm.2018.6074

By:

Song, Na;
Wang, Haijun;
Gu, Tengteng;
Qi, Jinbo;
Yang, Jun;
Qiu, Yanyan;
Chen, Qiuyue;
Zou, Yawen;
Chen, Yinze;
Hu, Qing;
Ma, Xiaoyan;
Zhao, Tiesuo;
Feng, Zhiwei

Publication type:

Article