Works about GUANINE nucleotide exchange factors

Results: 719

Plasma extracellular vesicle-associated miR-512-3p modulates angiogenesis in pediatric Moyamoya disease by targeting ARHGEF3.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08796-4

By:

Koh, Eun Jung;
Choi, Seung Ah;
Moon, Youn Joo;
Lee, Heeyoung;
Phi, Ji Hoon;
Kim, Seung-Ki

Publication type:

Article

Research‐Based Whole Genome Sequencing Identifies Biallelic Loss of Function Variants in DOCK3 Gene Causing DOCK3‐Related Disorder: The End of a Diagnostic Journey for This Family.

Published in:

Clinical Genetics, 2025, v. 108, n. 1, p. 109, doi. 10.1111/cge.14741

By:

Liaqat, Khurram;
Treat, Kayla;
Mantcheva, Lili;
McLaughlin, Aaron;
Breman, Amy;
McPheron, Molly;
Conboy, Erin;
Vetrini, Francesco

Publication type:

Article

Arhgef7 as a key target for enriched environment rescuing spatial cognitive deficits and anxiety-like behaviors in a mouse model of Alzheimer's disease following early social isolation.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01797-5

By:

Wang, Yimiao;
Wang, Ze;
Li, Yue;
Cao, Min;
Zhang, Shuying;
Ding, Shixin;
Chen, Sijia;
Jin, Yuxi;
Zhang, Yanli;
Gao, Junying;
Xiao, Ming

Publication type:

Article

Spontaneous Cdc42 Polarization Independent of GDI-Mediated Extraction and Actin-Based Trafficking.

Published in:

PLoS Biology, 2015, v. 13, n. 4, p. 1, doi. 10.1371/journal.pbio.1002097

By:

Bendezú, Felipe O.;
Vincenzetti, Vincent;
Vavylonis, Dimitrios;
Wyss, Romain;
Vogel, Horst;
Martin, Sophie G.

Publication type:

Article

Expanding the Regulatory Repertoire of GEFs.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001654

By:

Robinson, Richard

Publication type:

Article

Integrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001652

By:

Aizel, Kaheina;
Biou, Valérie;
Navaza, Jorge;
Duarte, Lionel V.;
Campanacci, Valérie;
Cherfils, Jacqueline;
Zeghouf, Mahel

Publication type:

Article

Crag Is a GEF for Rab11 Required for Rhodopsin Trafficking and Maintenance of Adult Photoreceptor Cells

Published in:

PLoS Biology, 2012, v. 10, n. 12, p. 1, doi. 10.1371/journal.pbio.1001438

By:

Xiong, Bo;
Bayat, Vafa;
Jaiswal, Manish;
Zhang, Ke;
Sandoval, Hector;
Charng, Wu-Lin;
Li, Tongchao;
David, Gabriela;
Duraine, Lita;
Lin, Yong-Qi;
Neely, G. Gregory;
Yamamoto, Shinya;
Bellen, Hugo J.

Publication type:

Article

The structure of a small GTPaseRhoA in complex with PDZRhoGEF and the inhibitor HL47.

Published in:

Biotechnology Letters, 2017, v. 39, n. 5, p. 745, doi. 10.1007/s10529-017-2292-7

By:

Yan, Zhaowei;
Ma, Sheng;
Zhang, Yan;
Ma, La;
Wang, Feng;
Li, Jian;
Miao, Liyan

Publication type:

Article

Structural Snapshots of a Dynamic Process in the Regulation of P-Rex, a Metastatic Factor.

Published in:

2019

By:

Cash, Jennifer N.;
Ravala, Sandeep;
Tesmer, John J.G.;
Cianfrocco, Michael A.

Publication type:

Abstract

New Advances in Live-cell Imaging: Multiplexed Protein Activity Measurements and Correlational Studies of Rho GTPase Regulation in Living Cells.

Published in:

2012

By:

Hodgson, L.;
Spiering, D.;
Sabouri, M.;
Der Mardirossian, C.;
Danuser, G.;
Hahn, K.

Publication type:

Abstract

RABIF promotes hepatocellular carcinoma progression through regulation of mitophagy and glycolysis.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07028-1

By:

Feng, Ning;
Zhang, Rui;
Wen, Xin;
Wang, Wei;
Zhang, Nie;
Zheng, Junnian;
Zhang, Longzhen;
Liu, Nianli

Publication type:

Article

IP3R at ER-Mitochondrial Contact Sites: Beyond the IP3R-GRP75-VDAC1 Ca2+ Funnel.

Published in:

Contact (25152564), 2023, v. 6, p. 1, doi. 10.1177/25152564231181020

By:

Atakpa-Adaji, Peace;
Ivanova, Adelina

Publication type:

Article

Differential Gene Expression in Circulating CD14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 127, doi. 10.3390/jcm9010127

By:

Liepelt, Anke;
Hohlstein, Philipp;
Gussen, Hendrik;
Xue, Jia;
Aschenbrenner, Anna C.;
Ulas, Thomas;
Buendgens, Lukas;
Warzecha, Klaudia T.;
Bartneck, Matthias;
Luedde, Tom;
Trautwein, Christian;
Schultze, Joachim L.;
Koch, Alexander;
Tacke, Frank

Publication type:

Article

Developmental patterning function of GNOM ARF-GEF mediated from the cell periphery.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.68993

By:

Adamowski, Maciek;
Matijević, Ivana;
Friml, Jiří

Publication type:

Article

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85167

By:

Bogucka-Janczi, Katarzyna;
Harms, Gregory;
Coissieux, Marie-May;
Bentires-Alj, Mohamed;
Thiede, Bernd;
Rajalingam, Krishnaraj

Publication type:

Article

The homeobox gene DLX4 promotes generation of human induced pluripotent stem cells.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07283

By:

Naritaka Tamaoki;
Kazutoshi Takahashi;
Hitomi Aoki;
Kazuki Iida;
Tomoko Kawaguchi;
Daijirou Hatakeyama;
Masatoshi Inden;
Naoyuki Chosa;
Akira Ishisaki;
Takahiro Kunisada;
Toshiyuki Shibata;
Naoki Goshima;
Shinya Yamanaka;
Ken-ichi Tezuka

Publication type:

Article

Conformational change of Sos-derived proline-rich peptide upon binding Grb2 N-terminal SH3 domain probed by NMR.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02913

By:

Kenji Ogura;
Hideyasu Okamura

Publication type:

Article

Molecular mechanisms of Sar/Arf GTPases in vesicular trafficking in yeast and plants.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00411

By:

Yorimitsu, Tomohiro;
Sato, Ken;
Takeuchi, Masaki

Publication type:

Article

RASGRP2 is a potential immune-related biomarker and regulates mitochondrial-dependent apoptosis in lung adenocarcinoma.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1100231

By:

Yongting Liu;
Yanhong Ouyang;
Ziyang Feng;
Zhaohui Jiang;
Jiayao Ma;
Xin Zhou;
Changjing Cai;
Ying Han;
Shan Zeng;
Shanshan Liu;
Hong Shen

Publication type:

Article

The complexity of Rab5 to Rab7 transition guarantees specificity of pathogen subversion mechanisms.

Published in:

Frontiers in Cellular & Infection Microbiology, 2014, p. 1, doi. 10.3389/fcimb.2014.00180

By:

Mottola, Giovanna

Publication type:

Article

Letter: Using non‐invasive fibrosis tests and emerging diagnostics to enhance the accuracy of liver fibrosis staging in MASLD patients.

Published in:

2025

By:

Meng, Wenjun;
Yao, Ping;
Dan, Yuan

Publication type:

Letter to the Editor

Landscape of lncRNAs expressed in Mexican patients with triple‑negative breast cancer.

Published in:

Molecular Medicine Reports, 2025, v. 31, n. 6, p. N.PAG, doi. 10.3892/mmr.2025.13528

By:

Castro-Oropeza, Rosario;
Velazquez-Velazquez, Cindy;
Vazquez-Santillan, Karla;
Mantilla-Morales, Alejandra;
Ruiz Tachiquin, Martha-Eugenia;
Torres, Javier;
Rios-Sarabia, Nora;
Mayani, Hector;
Piña-Sanchez, Patricia

Publication type:

Article

Involvement of Rac in thromboxane A2-induced human platelet activation: Regulation of sCD40 ligand release and PDGF-AB secretion.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 1, p. 107, doi. 10.3892/mmr.2014.2143

By:

YASUNARI KAGEYAMA;
TOMOAKI DOI;
RIE MATSUSHIMA-NISHIWAKI;
YUKO IIDA;
SHIGERU AKAMATSU;
AKIRA KONDO;
GEN KUROYANAGI;
NAOHIRO YAMAMOTO;
JUN MIZUTANI;
TAKANOBU OTSUKA;
HARUHIKO TOKUDA;
HIROKI IIDA;
OSAMU KOZAWA;
SHINJI OGURA

Publication type:

Article

KNDC1 knockdown protects human umbilical vein endothelial cells from senescence.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 1, p. 82, doi. 10.3892/mmr.2014.2201

By:

CHUNYAN ZHANG;
YONG-ZHAN ZHEN;
YA-JUN LIN;
JIANG LIU;
JIE WEI;
RONG XU;
GANG HU

Publication type:

Article

Roles Played by DOCK11, a Guanine Nucleotide Exchange Factor, in HBV Entry and Persistence in Hepatocytes.

Published in:

Viruses (1999-4915), 2024, v. 16, n. 5, p. 745, doi. 10.3390/v16050745

By:

Li, Ying-Yi;
Murai, Kazuhisa;
Lyu, Junyan;
Honda, Masao

Publication type:

Article

A Human and Rhesus Macaque Interferon-Stimulated Gene Screen Shows That Over-Expression of ARHGEF3/XPLN Inhibits Replication of Hepatitis C Virus and Other Flavivirids.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 8, p. 1655, doi. 10.3390/v14081655

By:

Bamford, Connor G. G.;
Aranday-Cortes, Elihu;
Sanchez-Velazquez, Ricardo;
Mullan, Catrina;
Kohl, Alain;
Patel, Arvind H.;
Wilson, Sam J.;
McLauchlan, John

Publication type:

Article

Confirmation of Hyperimmunoglobulin E Syndrome in Two Patients with an Ocular Problem: Detection of Two New DOCK8 Mutations.

Published in:

2022

By:

Saghafi, Shiva;
Zandieh, Fariborz;
Fazlollahi, Mohammad Reza;
Glocker, Cristina;
Frede, Natalie;
Buchta, Mary;
Linlin Yang;
Mahmoudi, Amir Hossein;
Houshmand, Massoud;
Pourpak, Zahra;
Grimbacher, Bodo;
Moin, Mostafa;
Yang, Linlin

Publication type:

journal article

Abstracts.

Published in:: Pigment Cell & Melanoma Research, 2020, v. 33, n. 4, p. 642, doi. 10.1111/pcmr.12871
Publication type:: Article

A commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA).

Published in:

PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0268848

By:

Prifti, Diogjena Katerina;
Lauzier, Annie;
Elowe, Sabine

Publication type:

Article

Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis.

Published in:

Platelets, 2018, v. 29, n. 2, p. 192, doi. 10.1080/09537104.2017.1336214

By:

Sevivas, Teresa;
Bastida, José María;
Paul, David S.;
Caparros, Eva;
Palma-Barqueros, Verónica;
Coucelo, Margarida;
Marques, Dalila;
Ferrer-Marín, Francisca;
González-Porras, José Ramón;
Vicente, Vicente;
Hernández-Rivas, Jesús María;
Watson, Steve P.;
Lozano, María Luisa;
Bergmeier, Wolfgang;
Rivera, José

Publication type:

Article

Genetic variation of the RASGRF1 regulatory region affects human hippocampus-dependent memory.

Published in:

Frontiers in Human Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fnhum.2014.00260

By:

Barman, Adriana;
Assmann, Anne;
Richter, Sylvia;
Soch, Joram;
Hartmut Schütze;
Torsten Wüstenberg;
Deibele, Anna;
Marieke Klein;
Richter, Anni;
Gusalija Behnisch;
Emrah Düzel;
Zenker, Martin;
Seidenbecher, Constanze I.;
Schott, Björn H.

Publication type:

Article

ARHGEF5 binds Drebrin and affects α-tubulin acetylation to direct neuronal morphogenesis and migration during mouse brain development.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1421932

By:

Ji-ye Kim;
Hee-Gon Hwang;
Hye-Jin Jeon;
Seung Il Kim;
Min-kyu Kim;
Jeong-Yoon Kim

Publication type:

Article

Design and Synthesis of New (SecinH3) Derivatives as Potential Cytohesin Inhibitors.

Published in:

Indian Journal of Pharmaceutical Sciences, 2014, v. 76, n. 5, p. 387

By:

HAYALLAH, ALAA M.

Publication type:

Article

BRAG2a Mediates mGluR-Dependent AMPA Receptor Internalization at Excitatory Postsynapses through the Interaction with PSD-95 and Endophilin 3.

Published in:

Journal of Neuroscience, 2020, v. 40, n. 22, p. 4277, doi. 10.1523/jneurosci.1645-19.2020

By:

Masahiro Fukaya;
Takeyuki Sugawara;
Yoshinobu Hara;
Makoto Itakura;
Masahiko Watanabe;
Hiroyuki Sakagami

Publication type:

Article

Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 4, p. 790, doi. 10.1523/JNEUROSCI.2197-16.2017

By:

Kotaro Furusawa;
Akiko Asada;
Pamela Urrutia;
Gonzalez-Billault, Christian;
Mitsunori Fukuda;
Shin-ichi Hisanaga

Publication type:

Article

Equivalent Activities of Repulsive Axon Guidance Receptors.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 4, p. 1140, doi. 10.1523/JNEUROSCI.3406-15.2016

By:

Hong Long;
Shingo Yoshikawa;
Thomas, John B.

Publication type:

Article

Oncogenic KRAS signalling in pancreatic cancer.

Published in:

British Journal of Cancer, 2014, v. 111, n. 5, p. 817, doi. 10.1038/bjc.2014.215

By:

Eser, S;
Schnieke, A;
Schneider, G;
Saur, D

Publication type:

Article

Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation.

Published in:

British Journal of Cancer, 2014, v. 110, n. 5, p. 1307, doi. 10.1038/bjc.2014.39

By:

Murray, D W;
Didier, S;
Chan, A;
Paulino, V;
Van Aelst, L;
Ruggieri, R;
Tran, N L;
Byrne, A T;
Symons, M

Publication type:

Article

Expression analyses of PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, during mouse brain development.

Published in:

Medical Molecular Morphology, 2021, v. 54, n. 2, p. 146, doi. 10.1007/s00795-020-00275-1

By:

Nishikawa, Masashi;
Ito, Hidenori;
Noda, Mariko;
Hamada, Nanako;
Tabata, Hidenori;
Nagata, Koh-ichi

Publication type:

Article

Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.

Published in:

Clinical Science, 2014, v. 126, n. 11/12, p. 829, doi. 10.1042/CS20130652

By:

ZEE, Robert Y. L.;
Qing-Mei WANG;
CHASMAN, Daniel I.;
RIDKER, Paul M.;
LIAO, James K.

Publication type:

Article

NGEF is a potential prognostic biomarker and could serve as an indicator for immunotherapy and chemotherapy in lung adenocarcinoma.

Published in:

BMC Pulmonary Medicine, 2024, v. 24, p. 1, doi. 10.1186/s12890-024-03046-1

By:

Chen, Xin;
Zhang, Tao;
He, Yan-qiu;
Miao, Ti-wei;
Yin, Jie;
Ding, Qian;
Yang, Mei;
Chen, Fang-ying;
Zeng, Hong-ping;
Liu, Jie;
Zhu, Qi

Publication type:

Article

Transcriptome analysis reveals miRNA expression profiles in hypothalamus tissues during the sexual development of Jining grey goats.

Published in:

BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10735-y

By:

Li, Qing;
Chao, Tianle;
Wang, Yanyan;
Xuan, Rong;
Guo, Yanfei;
He, Peipei;
Zhang, Lu;
Wang, Jianmin

Publication type:

Article

Key mRNAs and lncRNAs of pituitary that affect the reproduction of FecB + + small tail han sheep.

Published in:

BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10191-8

By:

Yang, Jianqi;
Tang, Jishun;
He, Xiaoyun;
Di, Ran;
Zhang, Xiaosheng;
Zhang, Jinlong;
Guo, Xiaofei;
Hu, Wenping;
Chu, Mingxing

Publication type:

Article

RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation.

Published in:

2018

By:

Wu, Nan;
Ren, Dong;
Li, Su;
Ma, Wenli;
Hu, Shaoyan;
Jin, Yan;
Xiao, Sheng

Publication type:

journal article

PI Kinase-EhGEF2-EhRho5 axis contributes to LPA stimulated macropinocytosis in Entamoeba histolytica.

Published in:

PLoS Pathogens, 2022, v. 18, n. 5, p. 1, doi. 10.1371/journal.ppat.1010550

By:

Apte, Achala;
Manich, Maria;
Labruyère, Elisabeth;
Datta, Sunando

Publication type:

Article

The type three secretion system effector protein IpgB1 promotes Shigella flexneri cell-to-cell spread through double-membrane vacuole escape.

Published in:

PLoS Pathogens, 2022, p. 1, doi. 10.1371/journal.ppat.1010380

By:

Weddle, Erin A.;
Köseoğlu, Volkan K.;
DeVasure, Brittany A.;
Agaisse, Hervé F.

Publication type:

Article

An atypical EhGEF regulates phagocytosis in Entamoeba histolytica through EhRho1.

Published in:

PLoS Pathogens, 2021, v. 17, n. 11, p. 1, doi. 10.1371/journal.ppat.1010030

By:

Bharadwaj, Ravi;
Kushwaha, Tushar;
Ahmad, Azhar;
Inampudi, Krishna K.;
Nozaki, Tomoyoshi;
Somlata

Publication type:

Article

Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways.

Published in:

PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009581

By:

Mbonye, Uri;
Leskov, Konstantin;
Shukla, Meenakshi;
Valadkhan, Saba;
Karn, Jonathan

Publication type:

Article

Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype.

Published in:

PLoS Genetics, 2019, v. 15, n. 2, p. 1, doi. 10.1371/journal.pgen.1007964

By:

Charron, Yves;
Willert, Jürgen;
Lipkowitz, Bettina;
Kusecek, Barica;
Herrmann, Bernhard G.;
Bauer, Hermann

Publication type:

Article

A single class of ARF GTPase activated by several pathway-specific ARF-GEFs regulates essential membrane traffic in Arabidopsis.

Published in:

PLoS Genetics, 2018, v. 14, n. 11, p. 1, doi. 10.1371/journal.pgen.1007795

By:

Singh, Manoj K.;
Richter, Sandra;
Beckmann, Hauke;
Kientz, Marika;
Stierhof, York-Dieter;
Anders, Nadine;
Fäßler, Florian;
Nielsen, Michael;
Knöll, Christian;
Thomann, Alexis;
Franz-Wachtel, Mirita;
Macek, Boris;
Skriver, Karen;
Pimpl, Peter;
Jürgens, Gerd

Publication type:

Article