Works matching DE "GRANZYMES"

Results: 607

Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1585446

By:

Broman, Meaghan M.;
Lanman, Nadia A.;
Vickman, Renee E.;
Cresswell, Gregory M.;
Kothandaraman, Harish;
Kolliegbo, Andree;
Paez, Juan Sebastian Paez;
Glaser, Alexander P.;
Helfand, Brian T.;
Henry, Gervaise;
Strand, Douglas W.;
Franco, Omar E.;
Hayward, Simon W.;
Ratliff, Timothy L.

Publication type:

Article

Pro-inflammatory granzyme K contributes extracellularly to disease.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1620670

By:

Turner, Christopher T.

Publication type:

Article

NKG7 is a Stable Marker of Cytotoxicity Across Immune Contexts and Within the Tumor Microenvironment.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202551885

By:

Turiello, Roberta;
Ng, Susanna S.;
Tan, Elisabeth;
van der Voort, Gemma;
Salim, Nazhifah;
Yong, Michelle C. R.;
Khassenova, Malika;
Oldenburg, Johannes;
Rühl, Heiko;
Hasenauer, Jan;
Surace, Laura;
Toma, Marieta;
Bald, Tobias;
Hölzel, Michael;
Corvino, Dillon

Publication type:

Article

LL-37 antimicrobial peptide and heterologous prime-boost vaccination regimen significantly induce HIV-1 Nef-Vpr antigen- and virion-specific immune responses in mice.

Published in:

Biotechnology Letters, 2023, v. 45, n. 1, p. 33, doi. 10.1007/s10529-022-03339-7

By:

Nikyar, Arash;
Bolhassani, Azam;
Agi, Elnaz

Publication type:

Article

In vivo delivery of a multiepitope peptide and Nef protein using novel cell-penetrating peptides for development of HIV-1 vaccine candidate.

Published in:

Biotechnology Letters, 2021, v. 43, n. 3, p. 547, doi. 10.1007/s10529-020-03060-3

By:

Davoodi, Saba;
Bolhassani, Azam;
Namazi, Fatemeh

Publication type:

Article

B1 protein: a novel cell penetrating protein for in vitro and in vivo delivery of HIV-1 multi-epitope DNA constructs.

Published in:

Biotechnology Letters, 2020, v. 42, n. 10, p. 1847, doi. 10.1007/s10529-020-02918-w

By:

Kardani, Kimia;
Bolhassani, Azam;
Agi, Elnaz;
Hashemi, Atieh

Publication type:

Article

The role of CD8+ Granzyme B+ T cells in the pathogenesis of Takayasu's arteritis.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 1, p. 167, doi. 10.1007/s10067-021-05903-4

By:

Li, Taotao;
Gao, Na;
Cui, Wei;
Zhao, Limin;
Du, Juan;
Shi, Xuemei;
Zhu, Junming;
Qiao, Zhiyu;
Guo, Shichao;
Pan, Lili

Publication type:

Article

Role of cytolytic impairment of natural killer and natural killer T-cell populations in rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2014, v. 33, n. 8, p. 1067, doi. 10.1007/s10067-014-2641-z

By:

Aggarwal, Ashish;
Sharma, Aman;
Bhatnagar, Archana

Publication type:

Article

PRSS23 在蛋鸡卵泡颗粒细胞的表达及其与卵泡液孕激素含量的关系研究.

Published in:

Journal of Henan Agricultural Sciences, 2020, v. 49, n. 5, p. 149, doi. 10.15933/j.cnki.1004-3268.2020.05.019

By:

孟金柱;
赵成刚;
罗碧秀;
赵园园

Publication type:

Article

Association Between Plasma Granzyme B Levels, Organ Failure, and 28-Day Mortality Prediction in Patients with Sepsis.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 5, p. 1461, doi. 10.3390/jcm14051461

By:

Ki, Min Seo;
Shin, Ju Hye;
Sung, Min Dong;
Chang, Shihwan;
Leem, Ah Young;
Lee, Su Hwan;
Park, Moo Suk;
Kim, Young Sam;
Chung, Kyung Soo

Publication type:

Article

Highlighting Fibroblasts Activation in Fibrosis: The State-of-The-Art Fibroblast Activation Protein Inhibitor PET Imaging in Cardiovascular Diseases.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 18, p. 6033, doi. 10.3390/jcm12186033

By:

Cui, Yan;
Wang, Yuxiang;
Wang, Shu;
Du, Bulin;
Li, Xuena;
Li, Yaming

Publication type:

Article

Prognostic Value of Interleukin-32 Expression and Its Correlation with the Infiltration of Natural Killer Cells in Cutaneous Melanoma.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 20, p. 4691, doi. 10.3390/jcm10204691

By:

Kang, Ji Young;
Kim, Kyung Eun

Publication type:

Article

Identification of Immunological Parameters as Predictive Biomarkers of Relapse in Patients with Chronic Myeloid Leukemia on Treatment-Free Remission.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 1, p. 42, doi. 10.3390/jcm10010042

By:

Vigón, Lorena;
Luna, Alejandro;
Galán, Miguel;
Rodríguez-Mora, Sara;
Fuertes, Daniel;
Mateos, Elena;
Piris-Villaespesa, Miguel;
Bautista, Guiomar;
San José, Esther;
Rivera-Torres, José;
Steegmann, Juan Luis;
de Ory, Fernando;
Pérez-Olmeda, Mayte;
Alcamí, José;
Planelles, Vicente;
López-Huertas, María Rosa;
García-Gutiérrez, Valentín;
Coiras, Mayte

Publication type:

Article

Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases.

Published in:

Journal of Immunology Research, 2023, p. 1, doi. 10.1155/2023/8924603

By:

Wu, Wai Chung;
Shiu, Carol;
Tong, Tak Keung;
Leung, Shui On;
Hui, Chin Wai

Publication type:

Article

GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells.

Published in:

Journal of Immunology Research, 2023, p. 1, doi. 10.1155/2023/5532617

By:

Ning, Jing;
Ding, Jianqiao;
Wang, Shu;
Jiang, Youhong;
Wang, Daqing;
Jiang, Shenyi

Publication type:

Article

Neutrophils inhibit CD8+ T cells immune response by arginase-1 signaling in patients with sepsis.

Published in:

World Journal of Emergency Medicine, 2022, v. 13, n. 4, p. 266, doi. 10.5847/wjem.j.1920-8642.2022.068

By:

Xiao-kang Dai;
Zhen-xing Ding;
Yuan-yuan Tan;
Hua-rui Bao;
Dong-yao Wang;
Hong Zhang

Publication type:

Article

Caspase-1 activates gasdermin A in nonmammals.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.92362

By:

Billman, Zachary Paul;
Kovacs, Stephen Bela;
Bo Wei;
Kidong Kang;
Cissé, Ousmane H.;
Miao, Edward A.

Publication type:

Article

Gene Profiling of Anti-Tumour Activity of Umbilical Cord Mesenchymal Stem Cells on Lymphoid Origin Tumour Cell Proliferation.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2017, v. 13, p. 33

By:

Sarmadi, Vahid Hosseinpour;
Heng Fong Seow;
King Hwa Ling;
Ramasamy, Rajesh

Publication type:

Article

Immune checkpoint inhibitors associated cardiovascular immune-related adverse events.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1340373

By:

Wonyoung Jo;
Taejoon Won;
Daoud, Abdel;
Čiháková, Daniela

Publication type:

Article

The roles of epigallocatechin gallate in the tumor microenvironment, metabolic reprogramming, and immunotherapy.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1331641

By:

Dongming Li;
Donghui Cao;
Yuanlin Sun;
Yingnan Cui;
Yangyu Zhang;
Jing Jiang;
Xueyuan Cao

Publication type:

Article

Immune checkpoint inhibitors as potential therapy for reverting T-cell exhaustion and reverting HIV latency in people living with HIV.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1270881

By:

Benito, José M.;
Restrepo, Clara;
García-Foncillas, Jesús;
Rallón, Norma

Publication type:

Article

Novel NKG2D-directed bispecific antibodies enhance antibodymediated killing of malignant B cells by NK cells and T cells.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1227572

By:

Lutz, Sebastian;
Klausz, Katja;
Albici, Anca-Maria;
Ebinger, Lea;
Sellmer, Lea;
Teipel, Hannah;
Frenzel, André;
Langner, Anna;
Winterberg, Dorothee;
Krohn, Steffen;
Hust, Michael;
Schirrmann, Thomas;
Dübel, Stefan;
Scherließ, Regina;
Humpe, Andreas;
Gramatzki, Martin;
Kellner, Christian;
Peipp, Matthias

Publication type:

Article

The effects of 5-aminolevulinic acid photodynamic therapy on the local immune response of women with cervical intraepithelial neoplasia grade 2.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1211114

By:

Anyue Wu;
Jing Niu;
Zubei Hong;
Liying Gu;
Yuli Huang;
Lihua Qiu

Publication type:

Article

MAIT cells altered phenotype and cytotoxicity in lupus patients are linked to renal disease severity and outcome.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1205405

By:

Litvinova, Elena;
Bounaix, Carine;
Hanouna, Guillaume;
Silva, Jennifer Da;
Noailles, Laura;
Beaudoin, Lucie;
Padden, Michael;
Bellamri, Nessrine;
Lehuen, Agnès;
Daugas, Eric;
Monteiro, Renato C.;
Flament, Heloïse

Publication type:

Article

Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1265255

By:

Jiajia Ma;
Shufang Yan;
Ying Zhao;
Huifang Yan;
Qian Zhang;
Xinxia Li

Publication type:

Article

Widespread and dynamic expression of granzyme C by skin-resident antiviral T cells.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1236595

By:

Lujan, Ramon A.;
Luxin Pei;
Shannon, John P.;
Dábilla, Nathânia;
Dolan, Patrick T.;
Hickman, Heather D.

Publication type:

Article

Cytotoxic innate intraepithelial lymphocytes control early stages of Cryptosporidium infection.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1229406

By:

Hariss, Fatima;
Delbeke, Marie;
Guyot, Karine;
Zarnitzky, Pauline;
Ezzedine, Mohamad;
Certad, Gabriela;
Meresse, Bertrand

Publication type:

Article

Human granzyme B regulatory B cells prevent effector CD4+CD25-T cell proliferation through a mechanism dependent from lymphotoxin alpha.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1183714

By:

Sailliet, Nicolas;
Mai, Hoa-Le;
Dupuy, Amandine;
Tilly, Gaëlle;
Fourgeux, Cynthia;
Braud, Martin;
Giral, Magali;
Robert, Jean-Michel;
Degauque, Nicolas;
Danger, Richard;
Poschmann, Jeremie;
Brouard, Sophie

Publication type:

Article

Phorbol-12-myristate-13-acetate is a potent enhancer of B cells with a granzyme B+ regulatory phenotype.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1194880

By:

Veh, Johanna;
Mangold, Charlotte;
Felsen, Anja;
Ludwig, Carolin;
Gerstner, Lisa;
Reinhardt, Peter;
Schrezenmeier, Hubert;
Fabricius, Dorit;
Jahrsdörfer, Bernd

Publication type:

Article

Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1211295

By:

Aybay, Erdem;
Jinhye Ryu;
Zhirong Fu;
Akula, Srinivas;
Enriquez, Erika Mendez;
Hallgren, Jenny;
Wernersson, Sara;
Olsson, Anna-Karin;
Hellman, Lars

Publication type:

Article

Noninvasive quantification of granzyme B in cardiac allograft rejection using targeted ultrasound imaging.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1164183

By:

Yunjie Jin;
Peng Gao;
Lifei Liang;
Yuhang Wang;
Jiawei Li;
Jiyan Wang;
Jiangang Hou;
Cheng Yang;
Xiaolin Wang

Publication type:

Article

Modeling cell-mediated immunity in human type 1 diabetes by engineering autoreactive CD8+ T cells.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1142648

By:

Peters, Leeana D.;
Wen-I Yeh;
Arnoletti, Juan M.;
Brown, Matthew E.;
Posgai, Amanda L.;
Mathews, Clayton E.;
Brusko, Todd M.

Publication type:

Article

Leptin deficiency in CD8+ T cells ameliorates non-segmental vitiligo by reducing interferon-γ and Granzyme B.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1158883

By:

Meiyu Wu;
Lu Wang;
Haijing Wu;
Ming Yang;
Zhenghao He;
Yiran Chen;
Huiming Zhang

Publication type:

Article

PD-1 limits differentiation and plasticity of Tc17 cells .

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1104730

By:

Arra, Aditya;
Lingel, Holger;
Pierau, Mandy;
Brunner-Weinzierl, Monika C.

Publication type:

Article

Soluble immune checkpoints as correlates for HIV persistence and T cell function in people with HIV on antiretroviral therapy.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1123342

By:

Chiu, Chris Y.;
Schou, Maya D.;
McMahon, James H.;
Deeks, Steven G.;
Fromentin, Rémi;
Chomont, Nicolas;
Wykes, Michelle N.;
Rasmussen, Thomas A.;
Lewin, Sharon R.

Publication type:

Article

Bioengineered bacterial outer membrane vesicles encapsulated Polybia-mastoparan I fusion peptide as a promising nanoplatform for bladder cancer immune-modulatory chemotherapy.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1129771

By:

Chunyu Ren;
Yangyang Li;
Zhaoqing Cong;
Zhuoran Li;
Leiming Xie;
Song Wu

Publication type:

Article

Mucosal-associated invariant T cells in patients with axial spondyloarthritis.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1128270

By:

van der Meer, Rienk Gerben;
Spoorenberg, Anneke;
Brouwer, Elisabeth;
der Meer, Berber Doornbos-van;
Boots, Annemieke M. H.;
Arends, Suzanne;
Abdulahad, Wayel H.

Publication type:

Article

Role of the granzyme family in rheumatoid arthritis: Current Insights and future perspectives.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1137918

By:

Yixin Zheng;
Jianan Zhao;
Yu Shan;
Shicheng Guo;
Schrodi, Steven J.;
Dongyi He

Publication type:

Article

Vaginal chlamydial clearance following primary or secondary infection in mice occurs independently of TNF-α.

Published in:

Frontiers in Cellular & Infection Microbiology, 2013, v. 3, p. 1, doi. 10.3389/fcimb.2013.00011

By:

Kamalakaran, Sangamithra;
Chaganty, Bharat K. R.;
Gupta, Rishein;
Guentzel, M. Neal;
Chambers, James P.;
Murthy, Ashlesh K.;
Arulanandam, Bernard P.;
Endsley, Janice;
Tvinnereim, Amy

Publication type:

Article

Comparison of the Anti-Inflammatory and Cytotoxic Potential of Different Corticosteroid Eye Drop Preparations.

Published in:

2020

By:

Urru, Matteo;
Ranieri, Giuseppe;
Mencucci, Rita;
Chiarugi, Alberto

Publication type:

journal article

Reply to: Understanding the Role of Regulatory T Cells in Non-asthmatic Eosinophilic Bronchitis.

Published in:

2020

By:

Liu, Jiaxing;
Zhan, Chen;
Huang, Jieru;
Chen, Ruchong

Publication type:

Letter

Cytotoxic granules in distinct subsets of cutaneous lupus erythematosus.

Published in:

Clinical & Experimental Dermatology, 2014, v. 39, n. 7, p. 835, doi. 10.1111/ced.12428

By:

Fogagnolo, L.;
Soares, T. C. B.;
Senna, C. G.;
Souza, E. M.;
Blotta, M. H. S. L.;
Cintra, M. L.

Publication type:

Article

Favorable Immunotherapy Plus Tyrosine Kinase Inhibition Outcome of Renal Cell Carcinoma Patients with Low CDK5 Expression.

Published in:

Cancer Research & Treatment, 2023, v. 55, n. 4, p. 1321, doi. 10.4143/crt.2022.1532

By:

Xianglai Xu;
Ying Wang;
Zhaoyi Chen;
Yanjun Zhu;
Jiajun Wang;
Jianming Guo

Publication type:

Article

The role of innate immune cells response in COVID-19.

Published in:

Journal of Medical & Allied Sciences, 2020, v. 10, n. 2, p. 41, doi. 10.5455/jmas.110798

By:

Khan, Aleem Ahmed

Publication type:

Article

Inhibition of granzyme B activity blocks inflammation induced by lipopolysaccharide through regulation of endoplasmic reticulum stress signaling in NK92 cells.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 580, doi. 10.3892/mmr.2018.8995

By:

Wang, Lei;
Jiang, Shaowei;
Xiao, Ling;
Chen, Lin;
Zhang, Yanyan;
Tong, Jing

Publication type:

Article

Regulation of Granzymes A and B by High-Risk HPV: Impact on Immune Evasion and Carcinogenesis.

Published in:

2025

By:

Maleka, Mashego Nathan;
Mbita, Zukile;
Morafo, Vivian

Publication type:

Literature Review

Restriction of Viral Glycoprotein Maturation by Cellular Protease Inhibitors.

Published in:

Viruses (1999-4915), 2024, v. 16, n. 3, p. 332, doi. 10.3390/v16030332

By:

Lotke, Rishikesh;
Petersen, Moritz;
Sauter, Daniel

Publication type:

Article

Little Brown Bats (Myotis lucifugus) Support the Binding of SARS-CoV-2 Spike and Are Likely Susceptible to SARS-CoV-2 Infection.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 5, p. 1103, doi. 10.3390/v15051103

By:

Chothe, Shubhada K.;
Jakka, Padmaja;
Boorla, Veda Sheersh;
Ramasamy, Santhamani;
Gontu, Abhinay;
Nissly, Ruth H.;
Brown, Justin;
Turner, Gregory;
Sewall, Brent J.;
Reeder, DeeAnn M.;
Field, Kenneth A.;
Engiles, Julie B.;
Amirthalingam, Saranya;
Ravichandran, Abirami;
LaBella, Lindsey;
Nair, Meera Surendran;
Maranas, Costas D.;
Kuchipudi, Suresh V.

Publication type:

Article

Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 9, p. 1976, doi. 10.3390/v14091976

By:

Posadas-Sánchez, Rosalinda;
Fragoso, José Manuel;
Sánchez-Muñoz, Fausto;
Rojas-Velasco, Gustavo;
Ramírez-Bello, Julian;
López-Reyes, Alberto;
Martínez-Gómez, Laura E.;
Sierra-Fernández, Carlos;
Rodríguez-Reyna, Tatiana;
Regino-Zamarripa, Nora Elemi;
Ramírez-Martínez, Gustavo;
Zuñiga-Ramos, Joaquín;
Vargas-Alarcón, Gilberto

Publication type:

Article

Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.

Published in:

Mucosal Immunology (1933-0219), 2012, v. 5, n. 2, p. 161, doi. 10.1038/mi.2011.62

By:

Loebbermann, J;
Thornton, H;
Durant, L;
Sparwasser, T;
Webster, K E;
Sprent, J;
Culley, F J;
Johansson, C;
Openshaw, P J

Publication type:

Article