Works matching DE "GRANZYMES"

Results: 584

Editorial: NK cells in the tumor microenvironment: immunosuppressive mechanisms and therapeutic opportunities.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1606236

By:

Ayuso, Jose M.;
De Waele, Jorrit

Publication type:

Article

In vivo delivery of a multiepitope peptide and Nef protein using novel cell-penetrating peptides for development of HIV-1 vaccine candidate.

Published in:

Biotechnology Letters, 2021, v. 43, n. 3, p. 547, doi. 10.1007/s10529-020-03060-3

By:

Davoodi, Saba;
Bolhassani, Azam;
Namazi, Fatemeh

Publication type:

Article

B1 protein: a novel cell penetrating protein for in vitro and in vivo delivery of HIV-1 multi-epitope DNA constructs.

Published in:

Biotechnology Letters, 2020, v. 42, n. 10, p. 1847, doi. 10.1007/s10529-020-02918-w

By:

Kardani, Kimia;
Bolhassani, Azam;
Agi, Elnaz;
Hashemi, Atieh

Publication type:

Article

Mass-Spectrometric Analysis of Proteome of Microvesicles Produced by NK-92 Natural Killer Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2018, v. 165, n. 4, p. 564, doi. 10.1007/s10517-018-4214-7

By:

Korenevskii, A. V.;
Milyutina, Yu. P.;
Zhdanova, A. A.;
Pyatygina, K. M.;
Sokolov, D. I.;
Sel’kov, S. A.

Publication type:

Article

Serine protease mediates Ovomermis sinensis‐inhibited host immune responses by inducing apoptosis: implications for successful parasitism and host mortality.

Published in:

Pest Management Science, 2024, v. 80, n. 4, p. 1968, doi. 10.1002/ps.7931

By:

Jiao, Zhenlong;
Chen, Mingming;
Zhao, Wenjing;
Wu, Yuanming;
Guo, Guo

Publication type:

Article

Analysis of the expression of FAP‐α protein in 2D‐keloid fibroblast cultures and in 3D models of keloid.

Published in:

Journal of Cosmetic Dermatology, 2022, v. 21, n. 8, p. 3561, doi. 10.1111/jocd.14667

By:

Katarzyna, Adamczyk;
Agnieszka, Garncarczyk;
Paweł, Antończak;
Magdalena, Kimsa‐Dudek;
Agnieszka, Synowiec‐Wojtarowicz;
Małgorzata, Derewniuk;
Agnieszka, Lubczyńska;
Dominika, Wcisło‐Dziadecka

Publication type:

Article

ACE2 role in SARS-CoV-2 infectivity and Covid-19 severity.

Published in:

Malaysian Journal of Pathology, 2020, v. 42, n. 3, p. 363

By:

AZIZAN, Elena;
BROWN, Morris

Publication type:

Article

Caspase-1 activates gasdermin A in nonmammals.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.92362

By:

Billman, Zachary Paul;
Kovacs, Stephen Bela;
Bo Wei;
Kidong Kang;
Cissé, Ousmane H.;
Miao, Edward A.

Publication type:

Article

Toxoplasma gondii suppress human cord blood cell differentiation to the NK cell population.

Published in:

Immunity, Inflammation & Disease, 2024, v. 12, n. 6, p. 1, doi. 10.1002/iid3.1329

By:

Mahmoudzadeh, Sepideh;
Dizaji Asl, Khadijeh;
Nozad Charoudeh, Hojjatollah;
Rahbarghazi, Reza;
Ahmadi, Mahdi;
Heidarzadeh, Morteza;
Spotin, Adel;
Ahmadpour, Ehsan

Publication type:

Article

Natural killer cell subsets and their functional molecules in peripheral blood of the patients with breast cancer.

Published in:

Immunity, Inflammation & Disease, 2024, v. 12, n. 4, p. 1, doi. 10.1002/iid3.1255

By:

Darvishvand, Reza;
Rezaeifard, Somayeh;
Kiani, Razie;
Tahmasebi, Sedigheh;
Faghih, Zahra;
Erfani, Nasrollah

Publication type:

Article

Innate CD8αα<sup>+</sup> lymphocytes enhance anti-CD40 antibody-mediated colitis in mice.

Published in:

Immunity, Inflammation & Disease, 2017, v. 5, n. 2, p. 109, doi. 10.1002/iid3.146

By:

Kumar, Aaram A.;
Delgado, Alberto G.;
Piazuelo, M. Blanca;
Van Kaer, Luc;
Olivares‐Villagómez, Danyvid

Publication type:

Article

Granzyme B inhibition reduces autoantibody‐induced dermal–epidermal separation in an ex vivo model of epidermolysis bullosa acquisita.

Published in:

Experimental Dermatology, 2024, v. 33, n. 9, p. 1, doi. 10.1111/exd.15172

By:

Emtenani, Shirin;
Lebhar, Hélène;
Marquis, Christopher P.;
Ludwig, Ralf J.;
Schmidt, Enno

Publication type:

Article

Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01379

By:

Lee, Yong Sun;
Yeo, In Jun;
Kim, Ki Cheon;
Han, Sang-Bae;
Hong, Jin Tae

Publication type:

Article

Single-Fluorescent Protein Reporters Allow Parallel Quantification of Natural Killer Cell-Mediated Granzyme and Caspase Activities in Single Target Cells.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01840

By:

Liesche, Clarissa;
Sauer, Patricia;
Prager, Isabel;
Urlaub, Doris;
Claus, Maren;
Eils, Roland;
Beaudouin, Joël;
Watzl, Carsten

Publication type:

Article

lncRNA MANCR Inhibits NK Cell Killing Effect on Lung Adenocarcinoma by Targeting miRNA-30d-5p.

Published in:

Cellular Microbiology, 2022, v. 2022, p. 1, doi. 10.1155/2022/4928635

By:

Lu, Yunping;
Rao, Xiao;
Zheng, Weifen;
Du, Yinggan;
Xue, Jianbo;
Huang, Kan

Publication type:

Article

Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from M ycobacterium tuberculosis-infected cynomolgus macaques.

Published in:

Cellular Microbiology, 2015, v. 17, n. 8, p. 1085, doi. 10.1111/cmi.12428

By:

Mattila, Joshua T.;
Maiello, Pauline;
Sun, Tao;
Via, Laura E.;
Flynn, JoAnne L.

Publication type:

Article

Favorable Immunotherapy Plus Tyrosine Kinase Inhibition Outcome of Renal Cell Carcinoma Patients with Low CDK5 Expression.

Published in:

Cancer Research & Treatment, 2023, v. 55, n. 4, p. 1321, doi. 10.4143/crt.2022.1532

By:

Xianglai Xu;
Ying Wang;
Zhaoyi Chen;
Yanjun Zhu;
Jiajun Wang;
Jianming Guo

Publication type:

Article

Pedunculagin isolated from Plinia cauliflora seeds exhibits genotoxic, antigenotoxic and cytotoxic effects in bacteria and human lymphocytes.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2022, v. 85, n. 9, p. 353, doi. 10.1080/15287394.2021.2009947

By:

Silva Fernandes, Amanda;
Hollanda Véras, Jefferson;
Silva, Luana Santos;
Puga, Sara Cristina;
Luiz Cardoso Bailão, Elisa Flávia;
de Oliveira, Matheus Gabriel;
Cardoso, Clever Gomes;
Carneiro, Cristiene Costa;
Costa Santos, Suzana Da;
Chen-Chen, Lee

Publication type:

Article

The anti-angiogenic tyrosine kinase inhibitor Pazopanib kills cancer cells and disrupts endothelial networks in biomimetic three-dimensional renal tumouroids.

Published in:

Journal of Tissue Engineering, 2020, v. 11, p. 1, doi. 10.1177/2041731420920597

By:

Stamati, Katerina;
Redondo, Patricia A;
Nyga, Agata;
Neves, Joana B;
Tran, Maxine GB;
Emberton, Mark;
Cheema, Umber;
Loizidou, Marilena

Publication type:

Article

The anti-angiogenic tyrosine kinase inhibitor Pazopanib kills cancer cells and disrupts endothelial networks in biomimetic three-dimensional renal tumouroids.

Published in:

Journal of Tissue Engineering, 2020, v. 11, p. 1, doi. 10.1177/2041731420920597

By:

Stamati, Katerina;
Redondo, Patricia A;
Nyga, Agata;
Neves, Joana B;
Tran, Maxine GB;
Emberton, Mark;
Cheema, Umber;
Loizidou, Marilena

Publication type:

Article

Evaluating the immunologically "cold" tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4 + and CD8 + T cells in breast cancer mouse models.

Published in:

Breast Cancer Research, 2024, v. 26, n. 1, p. 1, doi. 10.1186/s13058-024-01844-3

By:

Lu, Yun;
Houson, Hailey A.;
Gallegos, Carlos A.;
Mascioni, Alessandro;
Jia, Fang;
Aivazian, Argin;
Song, Patrick N.;
Lynch, Shannon E.;
Napier, Tiara S.;
Mansur, Ameer;
Larimer, Benjamin M.;
Lapi, Suzanne E.;
Hanker, Ariella B.;
Sorace, Anna G.

Publication type:

Article

Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality.

Published in:

PLoS ONE, 2023, v. 18, n. 8, p. 1, doi. 10.1371/journal.pone.0286109

By:

Kaur, Gurvinder;
Helmer, Rebecca A.;
Martinez-Marin, Dalia;
Sennoune, Souad R.;
Washburn, Rachel L.;
Martinez-Zaguilan, Raul;
Dufour, Jannette M.;
Chilton, Beverly S.

Publication type:

Article

Are owned dogs or stray dogs more prepared to diseases? A comparative study of immune system gene expression of perforin and granzymes.

Published in:

Acta Veterinaria Hungarica, 2022, v. 70, n. 1, p. 24, doi. 10.1556/004.2022.00005

By:

Temizkan, Mehmet Cevat;
Sonmez, Gonca

Publication type:

Article

Design and characterization of a novel human Granzyme B inhibitor.

Published in:

PEDS: Protein Engineering, Design & Selection, 2015, v. 28, n. 1, p. 9, doi. 10.1093/protein/gzu052

By:

Marcet-Palacios, Marcelo;
Ewen, Catherine;
Pittman, Elliot;
Duggan, Brenda;
Carmine-Simmen, Katia;
Fahlman, Richard P.;
Bleackley, R. Chris

Publication type:

Article

Immunologic Profiling of Human Metapneumovirus for the Development of Targeted Immunotherapy.

Published in:

2017

By:

Tzannou, Ifigeneia;
Nicholas, Sarah K.;
Lulla, Premal;
Aguayo-Hiraldo, Paibel I.;
Misra, Anisha;
Martinez, Caridad A.;
Machado, Annette A.;
Orange, Jordan S.;
Piedra, Pedro A.;
Vera, Juan F.;
Leen, Ann M.

Publication type:

journal article

Antitumor impact of amygdalin on adaptive immune response in BALB/c mice with breast cancer.

Published in:

Indian Journal of Experimental Biology, 2022, v. 60, n. 12, p. 887, doi. 10.56042/ijeb.v60i12.56791

By:

Yavari, Aboolfazl;
Zare, Fateme;
Dashti, Fateme;
Valizadeh, Hamideh;
Fesahat, Farzaneh;
Manshadi, Mahdi Dehghan

Publication type:

Article

Preclinical assessment of an anti-HTLV-1 heterologous DNA/MVA vaccine protocol expressing a multiepitope HBZ protein.

Published in:

Virology Journal, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12985-023-02264-z

By:

Daian e Silva, D. S. O.;
Cox, L. J.;
Rocha, A. S.;
Lopes-Ribeiro, Á.;
Souza, J. P. C.;
Franco, G. M.;
Prado, J. L. C.;
Pereira-Santos, T. A.;
Martins, M. L.;
Coelho-dos-Reis, J. G. A.;
Gomes-de-Pinho, T. M.;
Da Fonseca, F. G.;
Barbosa-Stancioli, E. F.

Publication type:

Article

Granzyme B + CD8 + T cells with terminal differentiated effector signature determine multiple sclerosis progression.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02810-0

By:

Shi, Ziyan;
Wang, Xiaofei;
Wang, Jiancheng;
Chen, Hongxi;
Du, Qin;
Lang, Yanlin;
Kong, Lingyao;
Luo, Wenqin;
Qiu, Yuhan;
Zhang, Ying;
Li, Chen;
Wen, Dingke;
Yao, Jie;
Cheng, Xia;
Cai, Linjun;
Lin, Xue;
Wang, Rui;
Mou, Zichao;
Li, Shuangjie;
Liu, Duanya

Publication type:

Article

Prediction and identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from endocan.

Published in:

Journal of Inflammation, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12950-020-00240-w

By:

Shao, Gaohai;
Liu, Qingjun;
Yang, Ling;
Feng, Guibo;
Zhao, Wang;
Huang, Zhongyan;
Yang, Zhao

Publication type:

Article

Human CD8+CD28− T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo.

Published in:

BMC Immunology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12865-020-00354-z

By:

Liu, Guihuan;
Yu, Yuming;
Feng, Fu;
Zhu, Ping;
Zhang, Hua;
Zhang, Danni;
Feng, Xiaoqiang;
Zhang, Zedan;
Liu, Yanjun

Publication type:

Article

Serum parameters in the spectrum of coeliac disease: beyond standard antibody testing - a cohort study.

Published in:

BMC Gastroenterology, 2012, v. 12, n. 1, p. 1, doi. 10.1186/1471-230X-12-159

By:

Tack, Greetje J.;
Van Wanrooij, Roy L. J.;
Von Blomberg, B Mary E.;
Amini, Hedayat;
Coupe, Veerle M. H.;
Bonnet, Petra;
Mulder, Chris J. J.;
Schreurs, Marco W. J.

Publication type:

Article

A phase I/II clinical trial on the efficacy and safety of NKT cells combined with gefitinib for advanced EGFR-mutated non-small-cell lung cancer.

Published in:

2021

By:

Yu, Wanjun;
Ye, Fei;
Yuan, Xiao;
Ma, Yali;
Mao, Chaoming;
Li, Xiaoqin;
Li, Jian;
Dai, Chunhua;
Qian, Fenhong;
Li, Junrong;
Fan, Xiujuan;
Zhou, Yuepeng;
Wang, Deqiang;
Guo, Zhenhong;
An, Huazhang;
Zhang, Minghui;
Chen, Deyu;
Xia, Sheng

Publication type:

journal article

Modeling antibody drug conjugate potential using a granzyme B antibody fusion protein.

Published in:

BMC Biology, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12915-024-01860-x

By:

Anderson, Trevor S.;
McCormick, Amanda L.;
Smith, Savanna L.;
Lowe, Devin B.

Publication type:

Article

Natural killer cells kill extracellular Pseudomonas aeruginosa using contact-dependent release of granzymes B and H.

Published in:

PLoS Pathogens, 2022, p. 1, doi. 10.1371/journal.ppat.1010325

By:

Feehan, David D.;
Jamil, Khusraw;
Polyak, Maria J.;
Ogbomo, Henry;
Hasell, Mark;
LI, Shu Shun;
Xiang, Richard F.;
Parkins, Michael;
Trapani, Joseph A.;
Harrison, Joe J.;
Mody, Christopher H.

Publication type:

Article

Noncytotoxic functions of killer cell granzymes in viral infections.

Published in:

2021

By:

de Jong, Lisanne C.;
Crnko, Sandra;
ten Broeke, Toine;
Bovenschen, Niels

Publication type:

Literature Review

Granzyme B inhibits keratinocyte migration by disrupting epidermal growth factor receptor (EGFR)-mediated signaling.

Published in:

Biological Chemistry, 2016, v. 397, n. 9, p. 883, doi. 10.1515/hsz-2016-0129

By:

Merkulova, Yulia;
Shen, Yue;
Parkinson, Leigh G.;
Raithatha, Sheetal A.;
Zhao, Hongyan;
Westendorf, Kathryn;
Sharma, Mehul;
Bleackley, Robert Chris;
Granville, David J.

Publication type:

Article

Are all granzymes cytotoxic in vivo?

Published in:

Biological Chemistry, 2014, v. 395, n. 2, p. 181, doi. 10.1515/hsz-2013-0238

By:

Joeckel, Lars T.;
Bird, Phillip I.

Publication type:

Article

Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli.

Published in:

PLoS Biology, 2020, v. 18, n. 6, p. 1, doi. 10.1371/journal.pbio.3000644

By:

Boulouis, Caroline;
Sia, Wan Rong;
Gulam, Muhammad Yaaseen;
Teo, Jocelyn Qi Min;
Png, Yi Tian;
Phan, Thanh Kha;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Poon, Ivan K. H.;
Koh, Tse Hsien;
Bergman, Peter;
Lim, Chwee Ming;
Wang, Lin-Fa;
Kwa, Andrea Lay Hoon;
Sandberg, Johan K.;
Leeansyah, Edwin

Publication type:

Article

Dual regulation effect and mechanism of human myeloid‐derived suppressor cells on anticolorectal cancer cells activity of Vγ9Vδ2 T cells.

Published in:

Cell Biochemistry & Function, 2024, v. 42, n. 1, p. 1, doi. 10.1002/cbf.3929

By:

Zhang, Mengyu;
Wu, Yuanyuan;
Qin, Yahan;
Shen, Jie;
Cui, Zhao;
Lei, Fan;
Zhang, Ke;
Li, Baiqing;
Liang, Shujuan;
Peng, Meiyu

Publication type:

Article

Targeting B7‐1 in immunotherapy.

Published in:

Medicinal Research Reviews, 2020, v. 40, n. 2, p. 654, doi. 10.1002/med.21632

By:

Chen, Rui;
Ganesan, Aravindhan;
Okoye, Isobel;
Arutyunova, Elena;
Elahi, Shokrollah;
Lemieux, M. Joanne;
Barakat, Khaled

Publication type:

Article

HTLV-1-infected asymptomatic carriers compared to HAM/TSP patients over-express the apoptosis- and cytotoxicity-related molecules.

Published in:

Medical Microbiology & Immunology, 2019, v. 208, n. 6, p. 835, doi. 10.1007/s00430-019-00625-6

By:

Mohammadi, Asadollah;
Fazeli, Bahare;
Poursina, Zohreh;
Tehranian, Farahnaz;
Vakili, Veda;
Boostani, Reza;
Rafatpanah, Houshang

Publication type:

Article

Human yeast-specific CD8 T lymphocytes show a nonclassical effector molecule profile.

Published in:

Medical Microbiology & Immunology, 2012, v. 201, n. 2, p. 127, doi. 10.1007/s00430-011-0213-2

By:

Breinig, Tanja;
Scheller, Nicoletta;
Glombitza, Birgit;
Breinig, Frank;
Meyerhans, Andreas

Publication type:

Article

N -Containing α-Mangostin Analogs via Smiles Rearrangement as the Promising Cytotoxic, Antitrypanosomal, and SARS-CoV-2 Main Protease Inhibitory Agents.

Published in:

Molecules, 2023, v. 28, n. 3, p. 1104, doi. 10.3390/molecules28031104

By:

Pyae, Nan Yadanar Lin;
Maiuthed, Arnatchai;
Phongsopitanun, Wongsakorn;
Ouengwanarat, Bongkot;
Sukma, Warongrit;
Srimongkolpithak, Nitipol;
Pengon, Jutharat;
Rattanajak, Roonglawan;
Kamchonwongpaisan, Sumalee;
Ei, Zin Zin;
Chunhacha, Preedakorn;
Wilasluck, Patcharin;
Deetanya, Peerapon;
Wangkanont, Kittikhun;
Hengphasatporn, Kowit;
Shigeta, Yasuteru;
Rungrotmongkol, Thanyada;
Chamni, Supakarn

Publication type:

Article

Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights.

Published in:

Molecules, 2021, v. 26, n. 21, p. 6616, doi. 10.3390/molecules26216616

By:

Pereira, Renato B.;
Pinto, Nuno F. S.;
Fernandes, Maria José G.;
Vieira, Tatiana F.;
Rodrigues, Ana Rita O.;
Pereira, David M.;
Sousa, Sérgio F.;
Castanheira, Elisabete M. S.;
Fortes, A. Gil;
Gonçalves, M. Sameiro T.

Publication type:

Article

PepFun: Open Source Protocols for Peptide-Related Computational Analysis.

Published in:

Molecules, 2021, v. 26, n. 6, p. 1664, doi. 10.3390/molecules26061664

By:

Ochoa, Rodrigo;
Cossio, Pilar;
Sippl, Wolfgang

Publication type:

Article

Granzyme B PET Imaging of the Innate Immune Response.

Published in:

Molecules, 2020, v. 25, n. 13, p. 3102, doi. 10.3390/molecules25133102

By:

Capaccione, Kathleen M.;
Doubrovin, Mikhail;
Bhatt, Nikunj;
Mintz, Akiva;
Molotkov, Andrei;
Roivainen, Anne

Publication type:

Article

M860, a Monoclonal Antibody against Human Lactoferrin, Enhances Tumoricidal Activity of Low Dosage Lactoferrin via Granzyme B Induction.

Published in:

Molecules, 2019, v. 24, n. 20, p. 3640, doi. 10.3390/molecules24203640

By:

Li, Ya;
Li, Jie;
Gong, Zheng;
Pan, Xiao-Hua;
Ma, Zi-Han;
Ma, Shu-Yan;
Wang, Hong-Min;
Dong, Hong-Liang;
Gong, Fang-Yuan;
Gao, Xiao-Ming

Publication type:

Article

Effect of ziram on natural killer, lymphokine-activated killer, and cytotoxic T lymphocyte activity.

Published in:

Archives of Toxicology, 2012, v. 86, n. 3, p. 475, doi. 10.1007/s00204-011-0771-5

By:

Li, Qing;
Kobayashi, Maiko;
Kawada, Tomoyuki

Publication type:

Article

Induction Therapies Determine the Distribution of Perforin and Granzyme B Transcripts in Kidney Transplant Recipients.

Published in:

Biomedicines, 2024, v. 12, n. 6, p. 1258, doi. 10.3390/biomedicines12061258

By:

Pipic, Dino;
Rasmussen, Marianne;
Saleh, Qais W.;
Tepel, Martin

Publication type:

Article

Effect of Granzyme K, FasL and Interferon-γ Expression in Placentas with Preeclampsia.

Published in:

Biomedicines, 2024, v. 12, n. 4, p. 842, doi. 10.3390/biomedicines12040842

By:

Vukoja, Martina;
Ćurlin, Marina;
Vukojević, Katarina;
Jelić-Knezović, Nevenka;
Kolobarić, Anita;
Orlović Vlaho, Martina;
Šoljić, Violeta

Publication type:

Article