Works about GRADIENT elution (Chromatography)

Results: 1150

Development and validation of a UPLC-MS/MS method for the quantification of parsaclisib and its application to pharmacokinetics and metabolic stability studies.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01569-0

By:

Zhou, Chenjian;
Wang, Peiqi;
Chen, Jie;
Wu, Hualu;
Yu, Yige

Publication type:

Article

Green HPLC strategy for quantification of carvedilol and hydrochlorothiazide in cardiac medications with in-vitro dissolution kinetics and impurity profiling.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01559-2

By:

Nabil, Mona;
Ahmed, Dina A.;
Abbas, Samah S.;
Lotfy, Hayam M.;
Marzouk, Hoda M.

Publication type:

Article

Eco-friendly QbD-optimized chromatographic method for simultaneous analysis of metronidazole and nicotinamide with applications in permeation, stability, and sustainability evaluation.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01555-6

By:

Kannaiah, Kanaka Parvathi;
Ali, Mohamed A. M.;
Chanduluru, Hemanth Kumar;
Chaudhary, Anis Ahmad;
El-Maghrabey, Mahmoud;
Obaydo, Reem H.;
Magdy, Galal;
Hamd, Mohamed A. El

Publication type:

Article

高效液相色谱法测定酱香型白酒中四种有机酸.

Published in:

China Brewing, 2025, v. 44, n. 6, p. 281, doi. 10.11882/j.issn.0254-5071.2025.06.040

By:

易宗伟;
蔡文超;
余培荣;
陈炜;
单春会;
王玉荣;
屈定武

Publication type:

Article

Mechanistic modeling of ligand density variations on anion exchange chromatography.

Published in:

Journal of Separation Science, 2021, v. 44, n. 4, p. 805, doi. 10.1002/jssc.202001077

By:

Sanchez‐Reyes, Gabriela;
Graalfs, Heiner;
Hafner, Mathias;
Frech, Christian

Publication type:

Article

Methods to determine the kinetic performance limit of contemporary chromatographic techniques.

Published in:

Journal of Separation Science, 2021, v. 44, n. 1, p. 323, doi. 10.1002/jssc.202000779

By:

Broeckhoven, Ken;
Desmet, Gert

Publication type:

Article

Sequential design of experiments approach for the multiproduct analysis of cholesterol‐lowering drugs by ultra‐high‐performance supercritical fluid chromatography.

Published in:

Journal of Separation Science, 2020, v. 43, n. 22, p. 4234, doi. 10.1002/jssc.202000702

By:

Santana, Igor Miranda;
Jardim, Isabel Cristina Sales Fontes;
Breitkreitz, Márcia Cristina

Publication type:

Article

Simultaneous determination of three iridoid glycosides of Rehmannia glutinosa in rat biological samples using a validated hydrophilic interaction–UHPLC–MS/MS method in pharmacokinetic and in vitro studies.

Published in:

Journal of Separation Science, 2020, v. 43, n. 22, p. 4148, doi. 10.1002/jssc.202000809

By:

Jeong, Seung‐Hyun;
Jang, Ji‐Hun;
Cho, Hea‐Young;
Lee, Yong‐Bok

Publication type:

Article

Comparison of the pharmacokinetic profiles of 13 phenolic acids and 6 triterpenes in normal and leukopenia rats after oral administration of Sanguisorba officinalis L. extract by LC‐MS/MS.

Published in:

Journal of Separation Science, 2020, v. 43, n. 22, p. 4103, doi. 10.1002/jssc.202000514

By:

Fan, Linzi;
Wang, Xiaotong;
Huang, Jing;
Gan, Chunli;
Jiang, Shuang;
Yang, Xinrong;
Yang, Chunjuan;
Yao, Meicun

Publication type:

Article

Broad targeted analysis of neurochemicals in rat serum using liquid chromatography tandem mass spectrometry with chemical derivatization.

Published in:

Journal of Separation Science, 2020, v. 43, n. 21, p. 4006, doi. 10.1002/jssc.202000709

By:

Meng, Xianshuang;
Bai, Hua;
Ma, Qiang;
Zhang, Peng;
Ma, Hong;
Deng, Yulin

Publication type:

Article

A multivariate quantification of Box‐Behnken design assisted method development and validation of dextromethorphan hydrobromide and desloratadine simultaneously by reverse‐phase HPLC in in‐house syrup formulation.

Published in:

Journal of Separation Science, 2020, v. 43, n. 18, p. 3597, doi. 10.1002/jssc.202000510

By:

Alam, Md. Irshad;
Siddiqui, Aquil ur‐Rahim;
Khanam, Nazia;
Kamaruddin, Shaikh Jalil

Publication type:

Article

Supercritical fluid chromatography in chiral separations: Evaluation of equivalency of polysaccharide stationary phases.

Published in:

Journal of Separation Science, 2020, v. 43, n. 13, p. 2675, doi. 10.1002/jssc.202000085

By:

Jakubec, Pavel;
Douša, Michal;
Nováková, Lucie

Publication type:

Article

Determination of oroxylin A, oroxylin A 7‐O‐glucuronide, and oroxylin A sodium sulfonate in beagle dogs by using UHPLC MS/MS Application in a pharmacokinetic study.

Published in:

Journal of Separation Science, 2020, v. 43, n. 12, p. 2290, doi. 10.1002/jssc.201901259

By:

Ren, Guanghui;
Chen, Huili;
Zhang, Mei;
Yang, Nan;
Yang, Hui;
Xu, Chuanru;
Li, Jiaming;
Ning, Chen;
Song, Zhongjin;
Zhou, Shiyu;
Zhang, Siliang;
Wang, Xiaoqian;
Lu, Yang;
Li, Ning;
Zhang, Yongjie;
Chen, Xijing;
Zhao, Di

Publication type:

Article

Quality consistency evaluation of commercial transfer factor injections by chromatographic fingerprint combined with multivariate statistical analysis.

Published in:

Journal of Separation Science, 2020, v. 43, n. 11, p. 2042, doi. 10.1002/jssc.201901145

By:

Huang, Qing;
Qian, Hanyu;
Feng, Dong;
Wang, Yao;
Luo, Nan;
Lu, Suya;
Shi, Qingshui;
Zhang, Mei;
Lu, Yihong;
Tan, Li

Publication type:

Article

Online high‐pH reversed‐phase liquid chromatography × low‐pH reversed‐phase liquid chromatography tandem electrospray ionization mass spectrometry combined with pulse elution gradient in the first dimension for the analysis of alkaloids in Macleaya cordata (willd.) R. Br

Published in:

Journal of Separation Science, 2020, v. 43, n. 8, p. 1423, doi. 10.1002/jssc.201900950

By:

Hu, Deping;
Li, Yuandong;
Zhao, Hui;
Zhao, Yang;
Huang, Si;
Li, Juan;
Li, Zhenjie;
Duan, Yuanxing;
Chen, Yingzhuang;
Xia, Jianjun

Publication type:

Article

HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.

Published in:

Journal of Separation Science, 2020, v. 43, n. 8, p. 1398, doi. 10.1002/jssc.201900534

By:

Marghany, Khaled A.;
Abdelsalam, Randa A.;
Haddad, Ghada M.

Publication type:

Article

A rapid and simple ultra high performance liquid chromatography method for the simultaneous determination of methoxyphenol derivatives involved in the eugenol catabolic pathway.

Published in:

Journal of Separation Science, 2020, v. 43, n. 5, p. 877, doi. 10.1002/jssc.201900939

By:

Singh, Archana;
Ghosh Sachan, Shashwati;
Mukhopadhyay, Kunal;
Kumar, Manish;
Sachan, Ashish

Publication type:

Article

Simultaneous quantitative analysis of nine constituents in six Chinese medicinal materials from Citrus genus by high‐performance liquid chromatography and high‐resolution mass spectrometry combined with chemometric methods.

Published in:

Journal of Separation Science, 2020, v. 43, n. 4, p. 736, doi. 10.1002/jssc.201901033

By:

Tian, Fang;
He, Xiao‐Fang;
Sun, Jie;
Liu, Xin‐Dan;
Zhang, Ying;
Cao, Hui;
Wu, Meng‐Hua;
Ma, Zhi‐Guo

Publication type:

Article

Ultra high performance liquid chromatography method development for separation of omeprazole and related substances on core‐shell columns using a Quality by Design approach.

Published in:

Journal of Separation Science, 2020, v. 43, n. 4, p. 696, doi. 10.1002/jssc.201900726

By:

Johansson, Emma;
Karlsson, Anders;
Ludvigsson, Jufang Wu

Publication type:

Article

A simple liquid chromatography coupled with tandem mass spectrometry approach for the simultaneous quantification of thirteen compounds in rats following oral administration of raw and processed Fructus Xanthii: Application in a comparative pharmacokinetic study

Published in:

Journal of Separation Science, 2019, v. 42, n. 22, p. 3403, doi. 10.1002/jssc.201900506

By:

Jiang, Hai;
Yang, Liu;
Xing, Xudong;
Yan, Meiling;
Guo, Xinyue;
Man, Wenjing;
Hou, Ajiao;
Yang, Bingyou;
Wang, Qiu‐Hong;
Kuang, Hai‐Xue

Publication type:

Article

Comprehensive stability‐indicating high‐performance liquid chromatography coupled with diode array detection method for simultaneous determination of amprolium hydrochloride and ethopabate in powder dosage form for veterinary use.

Published in:

Journal of Separation Science, 2019, v. 42, n. 21, p. 3340, doi. 10.1002/jssc.201900440

By:

Baker, Mostafa M.;
El‐Kafrawy, Dina S.;
Abdel‐Khalek, Magdi M.;
Belal, Tarek S.

Publication type:

Article

Liquid chromatography tandem mass spectrometry with triple stage fragmentation for highly selective analysis and pharmacokinetics of alarelin in rat plasma.

Published in:

Journal of Separation Science, 2019, v. 42, n. 18, p. 3033, doi. 10.1002/jssc.201900359

By:

Zhang, Zhi;
Li, Runzhi;
Liu, Shihao;
Yin, Lei;
Xu, Tongtong;
Fawcett, John Paul;
Gu, Jingkai

Publication type:

Article

Rapid simultaneous quantification of fructooligosaccharides in Morinda officianalis by ultra‐high performance liquid chromatography.

Published in:

Journal of Separation Science, 2019, v. 42, n. 13, p. 2222, doi. 10.1002/jssc.201801287

By:

Hao, Qingxiu;
Nan, Tiegui;
Zhou, Li;
Kang, Liping;
Guo, Lanping;
Yu, Yi

Publication type:

Article

Development and optimization of a supercritical fluid chromatography tandem mass spectrometry method for the high‐throughput determination of nimodipine in beagle plasma.

Published in:

Journal of Separation Science, 2019, v. 42, n. 12, p. 2179, doi. 10.1002/jssc.201900134

By:

Wang, Weiping;
Li, Pengyan;
Wu, Fengying;
Wang, Zhen;
Zhang, Tianhong

Publication type:

Article

Simultaneous high‐performance liquid chromatography with tandem mass spectrometry quantification of six bioactive components in rat plasma after oral administration of Yougui pill.

Published in:

Journal of Separation Science, 2019, v. 42, n. 10, p. 1867, doi. 10.1002/jssc.201800772

By:

Liu, Haolong;
Qiu, Feng;
Zhao, Haiyu;
Bian, Baolin;
Wang, Lei

Publication type:

Article

Comparative pharmacokinetics study of leonurine and stachydrine in normal rats and rats with cold‐stagnation and blood‐stasis primary dysmenorrhoea after the administration of Leonurus japonicus houtt electuary.

Published in:

Journal of Separation Science, 2019, v. 42, n. 9, p. 1725, doi. 10.1002/jssc.201801257

By:

Wen, Yan‐qing;
Gong, Li‐ying;
Wang, Lin;
Zhao, Nan;
Sun, Qi;
Kamara, Mohamed Olounfeh;
Ma, Hai‐ying;
Meng, Fan‐hao

Publication type:

Article

Establishing the chromatographic fingerprint of traditional Chinese medicine standard decoction based on quality by design approach: A case study of Licorice.

Published in:

Journal of Separation Science, 2019, v. 42, n. 6, p. 1144, doi. 10.1002/jssc.201800989

By:

Zhang, Hui;
Wang, Jianan;
Chen, Yan;
Shen, Xiaowei;
Jiang, Huijie;
Gong, Xingchu;
Yan, Jizhong

Publication type:

Article

Determination of major phenolic compounds in apples: Part I—Optimization of high‐performance liquid chromatography separation with diode array detection.

Published in:

Journal of Separation Science, 2018, v. 41, n. 15, p. 3042, doi. 10.1002/jssc.201800302

By:

Sklenářová, Hana;
Bílková, Aneta;
Pechová, Martina;
Chocholouš, Petr

Publication type:

Article

Simultaneous determination of 22 phthalate esters in polystyrene food‐contact materials by ultra‐performance convergence chromatography with tandem mass spectrometry.

Published in:

Journal of Separation Science, 2018, v. 41, n. 14, p. 2993, doi. 10.1002/jssc.201800094

By:

Fan, Ying‐Li;
Ma, Ming;
Cui, He‐Zhen;
Liu, Shu;
Yang, Min‐Li;
Hou, Xiu‐Feng

Publication type:

Article

Application of linear gradient elution in countercurrent chromatography for the separation of triterpenoid saponins from the roots of Pulsatilla koreana Nakai.

Published in:

Journal of Separation Science, 2017, v. 40, n. 13, p. 2810, doi. 10.1002/jssc.201700100

By:

Lee, Kyoung Jin;
Song, Kwangho;
Song, Da Young;
Kim, Yeong Shik

Publication type:

Article

High-performance liquid chromatographic cartridge with gradient elution capability coupled with UV absorbance detector and mass spectrometer for peptide and protein analysis.

Published in:

Journal of Separation Science, 2017, v. 40, n. 13, p. 2752, doi. 10.1002/jssc.201700185

By:

Lynch, Kyle B.;
Chen, Apeng;
Yang, Yu;
Lu, Joann J.;
Liu, Shaorong

Publication type:

Article

Istamycin aminoglycosides profiling and their characterization in Streptomyces tenjimariensis ATCC 31603 culture using high-performance liquid chromatography with tandem mass spectrometry.

Published in:

Journal of Separation Science, 2016, v. 39, n. 24, p. 4712, doi. 10.1002/jssc.201600925

By:

Hoang, Nguyen Huu;
Huong, Nguyen Lan;
Kim, Byul;
Sohng, Jae Kyung;
Yoon, Yeo Joon;
Park, Je Won

Publication type:

Article

Single-step enrichment of basophils from human peripheral blood by a novel method using a Percoll density gradient.

Published in:

Journal of Separation Science, 2016, v. 39, n. 15, p. 3062, doi. 10.1002/jssc.201600329

By:

Shiono, Hiroyuki;
Matsui, Takuya;
Okada, Tadashi;
Ito, Yoichiro

Publication type:

Article

Purification of vandaterosides from Vanda teres (Orchidaceae) by stepwise gradient centrifugal partition chromatography.

Published in:

Journal of Separation Science, 2015, v. 38, n. 17, p. 3006, doi. 10.1002/jssc.201500349

By:

Cakova, Veronika;
Urbain, Aurélie;
Quéméner, Céline;
Audo, Grégoire;
Bonté, Frédéric;
Lobstein, Annelise

Publication type:

Article

Development of a method using high-performance liquid chromatographic fingerprint and multi-ingredients quantitative analysis for the quality control of Yangxinshi Pian.

Published in:

Journal of Separation Science, 2015, v. 38, n. 17, p. 2989, doi. 10.1002/jssc.201500440

By:

Li, Yerui;
Yang, Kai;
Shi, Qiyuan;
Liu, Bowen;
Jin, Ye;
Liu, Xuesong;
Jiang, Zuolin;
Luan, Lianjun;
Wu, Yongjiang

Publication type:

Article

Separation of five compounds from leaves of Andrographis paniculata (Burm. f.) Nees by off-line two-dimensional high-speed counter-current chromatography combined with gradient and recycling elution.

Published in:

Journal of Separation Science, 2015, v. 38, n. 9, p. 1476, doi. 10.1002/jssc.201401458

By:

Zhang, Li;
Liu, Qi;
Yu, Jingang;
Zeng, Hualiang;
Jiang, Shujing;
Chen, Xiaoqing

Publication type:

Article

Simultaneous quantification of 25 active constituents in the total flavonoids extract from Herba Desmodii Styracifolii by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry.

Published in:

Journal of Separation Science, 2015, v. 38, n. 7, p. 1156, doi. 10.1002/jssc.201401360

By:

Guo, Panpan;
Yan, Wenying;
Han, Qingjie;
Wang, Chunying;
Zhang, Zijian

Publication type:

Article

High-performance liquid chromatographic column packings with different particle sizes: Chromatographic behavior for the quality analysis of HuanglianShangqing pill.

Published in:

Journal of Separation Science, 2015, v. 38, n. 3, p. 381, doi. 10.1002/jssc.201400981

By:

Yang, Dongzhi;
Li, Ying;
Yang, Fangxiu;
Du, Yan;
Li, Yinjie;
Zheng, Xiaoxiao;
Tang, Daoquan

Publication type:

Article

Determination of synthetic dyes in bean and meat products by liquid chromatography with tandem mass spectrometry.

Published in:

Journal of Separation Science, 2014, v. 37, n. 17, p. 2439, doi. 10.1002/jssc.201400349

By:

Li, Juan;
Ding, Xiaoming;
Zheng, Jiaxin;
Liu, Dandan;
Guo, Fei;
Liu, Hongmin;
Zhang, Yanbing

Publication type:

Article

Some insights on the description of gradient elution in reversed-phase liquid chromatography.

Published in:

Journal of Separation Science, 2014, v. 37, n. 17, p. 2269, doi. 10.1002/jssc.201400382

By:

Baeza‐Baeza, Juan José;
García‐Álvarez‐Coque, María Celia

Publication type:

Article

Modeling of salt and pH gradient elution in ion-exchange chromatography.

Published in:

Journal of Separation Science, 2014, v. 37, n. 1/2, p. 5, doi. 10.1002/jssc.201301007

By:

Schmidt, Michael;
Hafner, Mathias;
Frech, Christian

Publication type:

Article

Synthetic colorants: Analysis in pediatric over the counter drugs OTCs by HPLC and exposure risk to children.

Published in:

Journal of Research in Pharmacy, 2024, v. 28, n. 6, p. 2223, doi. 10.29228/jrp.893

By:

RAMADAN, Mai

Publication type:

Article

Development and Validation of a Novel Bioanalytical Method for Estimating Epigallocatechin 3 Gallate in Wistar Rat Plasma by RP-HPLC Employing Gradient Elution Techniques.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, n. 3, p. 1039, doi. 10.29228/jrp.397

By:

MANE, Varsha;
KILLEDAR, Suresh;
MORE, Harinath;
SALUNKHE, Sachin;
TARE, Harshal

Publication type:

Article

LC-MS/MS approach for the quantification of five genotoxic nitrosoimpurities in varenicline.

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 6, p. 1685, doi. 10.29228/jrp.259

By:

AMGOTH, Krishna Manjari Pawar;
TUMMALA, Sambasiva Rao

Publication type:

Article

Simultaneous Determination of Flurbiprofen and Thiocolchicoside in Pharmaceutical Preparations by a Validated HPLC Method.

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 3, p. 663, doi. 10.29228/jrp.163

By:

ASWAISSI, HAJER;
TÜRKÖZ ACAR, EBRU

Publication type:

Article

Liquid-liquid extraction and ultrafiltration based sample preparation technique for Q-TOF LC/MS analysis of nonpolar metabolites in human plasma samples.

Published in:

Journal of Research in Pharmacy, 2020, v. 24, n. 1, p. 38, doi. 10.35333/jrp.2020.111

By:

KOÇAK, Engin;
KAPLAN, Ozan;
ÇELEBİER, Mustafa

Publication type:

Article

Determination of synthetic colorants in cosmetic products by reversed-phase high-performance liquid chromatography coupled with diode-array detector.

Published in:

Journal of Research in Pharmacy, 2019, v. 23, n. 6, p. 1048, doi. 10.35333/jrp.2019.69

By:

FİLİZ, Zeynep;
OYMAK, Tülay;
DURAL, Emrah

Publication type:

Article

LC–MS/MS separation and quantitation of ribavirin in chicken and comparison of different mass spectrometric platforms.

Published in:

BMC Chemistry, 2023, v. 17, n. 1, p. 1, doi. 10.1186/s13065-023-01010-4

By:

Xu, Daokun;
Huang, Haolun;
Hu, Wenyan;
Liu, Xinmei;
Yang, Jun

Publication type:

Article

Validated HPLC–PDA methodology utilized for simultaneous determination of Etoricoxib and Paracetamol in the presence of Paracetamol toxic impurities.

Published in:

BMC Chemistry, 2022, v. 16, n. 1, p. 1, doi. 10.1186/s13065-022-00904-z

By:

Abdel Rahman, Mona A.;
Elghobashy, Mohamed R.;
Zaazaa, Hala E.;
Atty, Shimaa A.;
El-Mosallamy, Sally S.

Publication type:

Article

盐析辅助/通过式固相萃取-超高效液相色谱-串联质谱法测定网红减肥类食品中非法添加匹可硫酸钠

Published in:

Modern Food Science & Technology, 2024, v. 40, n. 8, p. 349, doi. 10.13982/j.mfst.1673-9078.2024.8.0548

By:

郑文静;
张艳侠;
孙立臻;
王明栋;
赵慧男;
孙珊珊;
薛霞;
王骏;
刘艳明

Publication type:

Article