Works about GLUCURONOSYLTRANSFERASE

Results: 512

Genetic polymorphisms of microsomal epoxide hydrolase and UDP-glucuronosyltransferase (UGT) and its effects on plasma carbamazepine levels and metabolic ratio in persons with epilepsy of South India: A cross-sectional genetic association study.

Published in:

Indian Journal of Pharmacology, 2023, v. 55, n. 3, p. 149, doi. 10.4103/ijp.ijp_228_22

By:

Venkatraman, Shravan;
Ramasamy, Kesavan;
Nair, Pradeep Pankajakshan

Publication type:

Article

Chemo‐Enzymatic Synthesis of Long‐Chain Oligosaccharides for Studying Xylan‐Modifying Enzymes.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202203941

By:

Álvarez‐Martínez, Ignacio;
Ruprecht, Colin;
Senf, Deborah;
Wang, Hsin‐tzu;
Urbanowicz, Breeanna R.;
Pfrengle, Fabian

Publication type:

Article

UGT1A11/28 and 1/ 6 genotypes have no effects on the efficacy and toxicity of FOLFIRI in Japanese patients with advanced colorectal cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 2, p. 279, doi. 10.1007/s00280-010-1485-8

By:

Sunakawa, Yu;
Ichikawa, Wataru;
Fujita, Ken-ichi;
Nagashima, Fumio;
Ishida, Hiroo;
Yamashita, Keishi;
Mizuno, Keiko;
Miwa, Keisuke;
Kawara, Kaori;
Akiyama, Yuko;
Araki, Kazuhiro;
Yamamoto, Wataru;
Miya, Toshimichi;
Narabayashi, Masaru;
Ando, Yuichi;
Hirose, Takashi;
Saji, Shigehira;
Sasaki, Yasutsuna

Publication type:

Article

Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of β-glucuronidase activity in intestinal lumen.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 1, p. 201, doi. 10.1007/s00280-010-1310-4

By:

Kurita, Akinobu;
Kado, Shoichi;
Matsumoto, Tsuneo;
Asakawa, Naoyuki;
Kaneda, Norimasa;
Kato, Ikuo;
Uchida, Kazumi;
Onoue, Masaharu;
Yokokura, Teruo

Publication type:

Article

The small-molecule tyrosine kinase inhibitor nilotinib is a potent noncompetitive inhibitor of the SN-38 glucuronidation by human UGT1A1.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 1, p. 237, doi. 10.1007/s00280-010-1445-3

By:

Fujita, Ken-ichi;
Sugiyama, Minako;
Akiyama, Yuko;
Ando, Yuichi;
Sasaki, Yasutsuna

Publication type:

Article

Association of UGT2B7 and ABCB1 genotypes with morphine-induced adverse drug reactions in Japanese patients with cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 251, doi. 10.1007/s00280-009-1029-2

By:

Fujita, Ken-ichi;
Ando, Yuichi;
Yamamoto, Wataru;
Miya, Toshimichi;
Endo, Hisashi;
Sunakawa, Yu;
Araki, Kazuhiro;
Kodama, Keiji;
Nagashima, Fumio;
Ichikawa, Wataru;
Narabayashi, Masaru;
Akiyama, Yuko;
Kawara, Kaori;
Shiomi, Mari;
Ogata, Hiroyasu;
Iwasa, Hiroyasu;
Okazaki, Yasushi;
Hirose, Takashi;
Sasaki, Yasutsuna

Publication type:

Article

The effect of transcatheter arterial chemoembolization on phase II drug metabolism enzymes in patients with hepatocellular carcinoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 347, doi. 10.1007/s00280-009-1040-7

By:

Yan Zhang;
Yanyan Jia;
Xinyou Liu;
Linna Liu;
Qingwei Wang;
Aidong Wen

Publication type:

Article

Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 65, n. 1, p. 97, doi. 10.1007/s00280-009-1008-7

By:

Denlinger, Crystal S.;
Blanchard, Rebecca;
Lu Xu;
Bernaards, Coen;
Litwin, Samuel;
Spittle, Cynthia;
Berg, Daniel J.;
McLaughlin, Susan;
Redlinger, Maryann;
Dorr, Andrew;
Hambleton, Julie;
Holden, Scott;
Kearns, Anne;
Kenkare-Mitra, Sara;
Lum, Bert;
Meropol, Neal J.;
O'Dwyer, Peter J.

Publication type:

Article

UGT1A1 polymorphism and hyperbilirubinemia in a patient who received sorafenib.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 65, n. 1, p. 1, doi. 10.1007/s00280-009-1096-4

By:

Meza-Junco, Judith;
Chu, Quincy S.-C.;
Christensen, Olaf;
Rajagopalan, Prabhu;
Das, Soma;
Stefanyschyn, Ruslan;
Sawyer, Michael B.

Publication type:

Article

Involvement of UDP-glucuronosyltransferase activity in irinotecan-induced delayed-onset diarrhea in rats.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 61, n. 4, p. 595, doi. 10.1007/s00280-007-0512-x

By:

Onoue, Masaharu;
Kurita, Akinobu;
Kado, Shoichi;
Matsumoto, Tsuneo;
Kaneda, Norimasa;
Uchida, Kazumi;
Kato, Ikuo;
Yokokura, Teruo

Publication type:

Article

Identification of human uridine diphosphateglucuronosyltransferase isoforms responsible for the glucuronidation of 10,11-dihydro-10-hydroxy-carbazepine.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 3, p. 388, doi. 10.1093/jpp/rgaa059

By:

Kai Huang;
Linling Que;
Ying Ding;
Nannan Chu;
Zhenzhong Qian;
Wei Qin;
Yuanxing Chen;
Jisheng Zhang;
Qing He

Publication type:

Article

Mechanism of in-vitro inhibition of UGT1A1 by paritaprevir.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 12, p. 1794, doi. 10.1111/jphp.12821

By:

Alam, Novera;
Angeli, Mia G.;
Greenblatt, David J.

Publication type:

Article

Identification and characterization of human UDP-glucuronosyltransferases responsible for the in-vitro glucuronidation of arctigenin.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 12, p. 1673, doi. 10.1111/jphp.12483

By:

Xin, Hong;
Xia, Yang‐Liu;
Hou, Jie;
Wang, Ping;
He, Wei;
Yang, Ling;
Ge, Guang‐Bo;
Xu, Wei

Publication type:

Article

Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1 A9 and UGT2 B7.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 4, p. 583, doi. 10.1111/jphp.12351

By:

Wu, Zhufeng;
Liu, Hongming;
Wu, Baojian

Publication type:

Article

Evidence for regulation of UDP-glucuronosyltransferase ( UGT) 1 A1 protein expression and activity via DNA methylation in healthy human livers.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 6, p. 874, doi. 10.1111/jphp.12053

By:

Yasar, Umit;
Greenblatt, David J.;
Guillemette, Chantal;
Court, Michael H.

Publication type:

Article

Glucuronidation of the broad-spectrum antiviral drug arbidol by UGT isoforms.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 4, p. 521, doi. 10.1111/jphp.12014

By:

Song, Jin‐Hui;
Fang, Zhong‐Ze;
Zhu, Liang‐Liang;
Cao, Yun‐Feng;
Hu, Cui‐Min;
Ge, Guang‐Bo;
Zhao, De‐Wei

Publication type:

Article

Altered expression of MRP2, MRP3 and UGT2B1 in the liver affects the disposition of morphine and its glucuronide conjugate in a rat model of cholestasis.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 9, p. 1205

By:

Shoji Fukushima

Publication type:

Article

Frequency of dihydropyrimidine dehydrogenase and UDP-glucuronosyltransferase 1A1 variants in cancer patients requiring chemotherapy: A single-center study in southern India.

Published in:

Journal of Clinical & Basic Research, 2023, v. 7, n. 1, p. 6, doi. 10.61186/jcbr.7.1.6

By:

Gangavarapu, Kevin;
Bora, Nandini Shyamali;
Srinivas, Maddali;
Hasan, Qurratulain

Publication type:

Article

Correction to: A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation.

Published in:

2022

By:

Robin, Shannon;
Hassine, Khalil Ben;
Muthukumaran, Jayaraman;
Jurkovic Mlakar, Simona;
Krajinovic, Maja;
Nava, Tiago;
Uppugunduri, Chakradhara Rao S.;
Ansari, Marc

Publication type:

Correction Notice

A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-021-00402-5

By:

Robin, Shannon;
Hassine, Khalil Ben;
Muthukumaran, Jayaraman;
Jurkovic Mlakar, Simona;
Krajinovic, Maja;
Nava, Tiago;
Uppugunduri, Chakradhara Rao S.;
Ansari, Marc

Publication type:

Article

Prevalence of uridine glucuronosyl transferase 1A1 (UGT1A1) mutations in Malay neonates with severe jaundice.

Published in:

Malaysian Journal of Pathology, 2011, v. 33, n. 2, p. 95

By:

Azlin, I.;
Wong, F. L.;
Ezham, M.;
Hafiza, A.;
Ainoon, O.

Publication type:

Article

Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes.

Published in:

Experimental Dermatology, 2012, v. 21, n. 5, p. 364, doi. 10.1111/j.1600-0625.2012.01478.x

By:

Götz, Christine;
Pfeiffer, Roland;
Tigges, Julia;
Ruwiedel, Karsten;
Hübenthal, Ulrike;
Merk, Hans F;
Krutmann, Jean;
Edwards, Robert J.;
Abel, Josef;
Pease, Camilla;
Goebel, Carsten;
Hewitt, Nicola;
Fritsche, Ellen

Publication type:

Article

Molecular Analysis of the UGT1A1 Gene in Korean Patients with Crigler-Najjar Syndrome Type II.

Published in:

Pediatric Gastroenterology, Hepatology & Nutrition, 2014, v. 17, n. 1, p. 37, doi. 10.5223/pghn.2014.17.1.37

By:

Jae Sung Ko;
Ju Young Chang;
Jin Soo Moon;
Hye Ran Yang;
Jeong Kee Seo

Publication type:

Article

Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00437

By:

Neumann, Elizabeth;
Mehboob, Huma;
Ramírez, Jacqueline;
Mirkov, Snezana;
Min Zhang;
Wanqing Liu

Publication type:

Article

Introduction of an N-Glycosylation Site into UDP-Glucuronosyltransferase 2B3 Alters Its Sensitivity to Cytochrome P450 3A1-Dependent Modulation.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00427

By:

Tatsuro Nakamura;
Naho Yamaguchi;
Yuu Miyauchi;
Tomoki Takeda;
Yasushi Yamazoe;
Kiyoshi Nagata;
Mackenzie, Peter I.;
Hideyuki Yamada;
Yuji Ishii

Publication type:

Article

Structure and Protein-Protein Interactions of Human UDP-Glucuronosyltransferases.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00388

By:

Ryoichi Fujiwara;
Tsuyoshi Yokoi;
Miki Nakajima

Publication type:

Article

Epstein–Barr virus latent membrane protein 2A upregulates UDP-glucose dehydrogenase gene expression via ERK and PI3K/Akt pathway.

Published in:

Cellular Microbiology, 2008, v. 10, n. 12, p. 2447, doi. 10.1111/j.1462-5822.2008.01221.x

By:

Yun-Ru Pan;
Vatsyayan, Jaya;
Yu-Sun Chang;
Hwan-You Chang

Publication type:

Article

Blick nach Asien.

Published in:

Nachrichten aus der Chemie, 2021, v. 69, n. 3, p. 30, doi. 10.1002/nadc.20214108738

By:

Schmid, Rolf

Publication type:

Article

Regulation of Epidermal Growth Factor Receptor Through Interaction of Ganglioside GM3 with GlcNAc of N-Linked Glycan of the Receptor: Demonstration in ldlD Cells.

Published in:

Neurochemical Research, 2011, v. 36, n. 9, p. 1645, doi. 10.1007/s11064-010-0379-9

By:

Guan, Feng;
Handa, Kazuko;
Hakomori, Sen-itiroh

Publication type:

Article

Binding of the substrate UDP-glucuronic acid induces conformational changes in the xanthan gum glucuronosyltransferase.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 6, p. 197, doi. 10.1093/protein/gzw007

By:

Salinas, S. R.;
Petruk, A. A.;
Brukman, N. G.;
Bianco, M. I.;
Jacobs, M.;
Marti, M. A.;
Ielpi, L.

Publication type:

Article

Regulation of Sulfotransferase and UDP-Glucuronosyltransferase Gene Expression by the PPARs.

Published in:

PPAR Research, 2009, p. 1, doi. 10.1155/2009/728941

By:

Runge-Morris, Melissa;
Kocarek, Thomas A.

Publication type:

Article

Effect of UDP-Glucuronosyltransferase (UGT) 1A Polymorphism (rs8330 and rs10929303) on Glucuronidation Status of Acetaminophen.

Published in:

Dose-Response, 2017, v. 15, n. 3, p. 1, doi. 10.1177/1559325817723731

By:

Mehboob, Huma;
Tahir, Imtiaz Mahmood;
Tahiral, Tahira;
Saleem, Sadaf;
Perveen, Sofia;
Farooqi, Aboubakker

Publication type:

Article

Functional analysis of a cotton glucuronosyltransferase promoter in transgenic tobaccos.

Published in:

Cell Research, 2007, v. 17, n. 2, p. 174, doi. 10.1038/sj.cr.7310119

By:

Ai-Min Wu;
Shi-You Lv;
Jin-Yuan Liu

Publication type:

Article

Combined effect of regulatory polymorphims on transcription of UGT1A1 as a cause of Gilbert syndrome.

Published in:

BMC Gastroenterology, 2010, v. 10, p. 57, doi. 10.1186/1471-230X-10-57

By:

Matsui, Katsuyuki;
Maruo, Yoshihiro;
Sato, Hiroshi;
Takeuchi, Yoshihiro

Publication type:

Article

Partial Purification and Characterization of UDP-Glucose-4-Epimerase from Solieria chordalis (Rhodophyceae).

Published in:

Botanica Marina, 2003, v. 46, n. 1, p. 107, doi. 10.1515/BOT.2003.011

By:

Goulard, F.;
Pondaven, P.;
Diouris, M.;
Deslandes, E.;
Floc'h, J. Y.

Publication type:

Article

Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2002, v. 17, n. 5, p. 233, doi. 10.1002/hup.403

By:

Linnet, Kristian

Publication type:

Article

Lycium Barbarum Polysaccharides and Wolfberry Juice Prevent DEHP-Induced Hepatotoxicity via PXR-Regulated Detoxification Pathway.

Published in:

Molecules, 2021, v. 26, n. 4, p. 859, doi. 10.3390/molecules26040859

By:

Liu, Huan;
Zhou, Xiong;
Huang, Shaowen;
Yang, Jie;
Liu, Ruijing;
Liu, Chunhong;
Colliec-Jouault, Sylvia

Publication type:

Article

In Vitro Interaction of AB-FUBINACA with Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes and Drug Transporters.

Published in:

Molecules, 2020, v. 25, n. 19, p. 4589, doi. 10.3390/molecules25194589

By:

Kim, Sunjoo;
Kim, Dong Kyun;
Shin, Yongho;
Jeon, Ji-Hyeon;
Song, Im-Sook;
Lee, Hye Suk

Publication type:

Article

In Vitro Inhibitory Effects of APINACA on Human Major Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Drug Transporters.

Published in:

Molecules, 2019, v. 24, n. 16, p. 3000, doi. 10.3390/molecules24163000

By:

Kim, Sunjoo;
Choi, Won-Gu;
Kwon, Mihwa;
Lee, Sowon;
Cho, Yong-Yeon;
Lee, Joo Young;
Kang, Han Chang;
Song, Im-Sook;
Lee, Hye Suk;
Gütschow, Michael

Publication type:

Article

Upregulation of UDP-Glucuronosyltransferases 1a1 and 1a7 Are Involved in Altered Puerarin Pharmacokinetics in Type II Diabetic Rats.

Published in:

Molecules, 2018, v. 23, n. 6, p. 1487, doi. 10.3390/molecules23061487

By:

Dong, Songtao;
Zhang, Maofan;
Niu, Huimin;
Jiang, Kunyu;
Jiang, Jialei;
Ma, Yinglin;
Wang, Xin;
Meng, Shengnan;
McPhee, Derek J.

Publication type:

Article

In Vitro Comparative Study of the Inhibitory Effects of Mangiferin and Its Aglycone Norathyriol towards UDP-Glucuronosyl Transferase (UGT) Isoforms.

Published in:

Molecules, 2017, v. 22, n. 6, p. 1008, doi. 10.3390/molecules22061008

By:

Dan Sun;
Chun-Ze Zhang;
Rui-Xue Ran;
Yun-Feng Cao;
Zuo Du;
Zhi-Wei Fu;
Chun-Ting Huang;
Zhen-Ying Zhao;
Wei-Hua Zhang;
Zhong-Ze Fang

Publication type:

Article

Multiple UDP-Glucuronosyltransferase and Sulfotransferase Enzymes are Responsible for the Metabolism of Verproside in Human Liver Preparations.

Published in:

Molecules, 2017, v. 22, n. 4, p. 670, doi. 10.3390/molecules22040670

By:

Ju-Hyun Kim;
Deok-Kyu Hwang;
Ju-Yeon Moon;
Yongnam Lee;
Ji Seok Yoo;
Dae Hee Shin;
Hye Suk Lee

Publication type:

Article

AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 50-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.

Published in:

Molecules, 2017, v. 22, n. 3, p. 443, doi. 10.3390/molecules22030443

By:

Ju-Hyun Kim;
Soon-Sang Kwon;
Tae Yeon Kong;
Jae Chul Cheong;
Hee Seung Kim;
Moon Kyo In;
Hye Suk Lee

Publication type:

Article

Evaluation and Comparison of the Inhibition Effect of Astragaloside IV and Aglycone Cycloastragenol on Various UDP-Glucuronosyltransferase (UGT) Isoforms.

Published in:

Molecules, 2016, v. 21, n. 12, p. 1616, doi. 10.3390/molecules21121616

By:

Ruixue Ran;
Chunze Zhang;
Rongshan Li;
Bowei Chen;
Weihua Zhang;
Zhenying Zhao;
Zhiwei Fu;
Zuo Du;
Xiaolang Du;
Xiaolong Yang;
Zhongze Fang

Publication type:

Article

In Vitro Inhibition of Human UDP-Glucuronosyl-Transferase (UGT) Isoforms by Astaxanthin, β-Cryptoxanthin, Canthaxanthin, Lutein, and Zeaxanthin: Prediction of in Vivo Dietary Supplement-Drug Interactions.

Published in:

Molecules, 2016, v. 21, n. 8, p. 1052, doi. 10.3390/molecules21081052

By:

Yu Fen Zheng;
Jee Sun Min;
Doyun Kim;
Jung Bae Park;
Sung-Wook Choi;
Eun Seong Lee;
Kun Na;
Soo Kyung Bae

Publication type:

Article

Effect of Honokiol on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.

Published in:

Molecules, 2013, v. 18, n. 9, p. 10681, doi. 10.3390/molecules180910681

By:

Hyeon-Uk Jeong;
Tae Yeon Kong;
Soon Sang Kwon;
Sung-Woon Hong;
Sung Hum Yeon;
Jun-Ho Choi;
Jae Young Lee;
Yong Yeon Cho;
Hye Suk Lee

Publication type:

Article

Demethylzeylasteral Exhibits Strong Inhibition towards UDP-Glucuronosyltransferase (UGT) 1A6 and 2B7.

Published in:

Molecules, 2012, v. 17, n. 8, p. 9469, doi. 10.3390/molecules17089469

By:

Jin-Wen Zhao;
Gui-Hua Wang;
Min Chen;
Lian-Hua Cheng;
Xiao-Qi Ji

Publication type:

Article

Strong Inhibition of Celastrol Towards UDP-Glucuronosyl Transferase (UGT) 1A6 and 2B7 Indicating Potential Risk of UGT-Based Herb-Drug Interaction.

Published in:

Molecules, 2012, v. 17, n. 6, p. 6832, doi. 10.3390/molecules17066832

By:

Yong-Sheng Zhang;
Yan-Yang Tu;
Xing-Chun Gao;
Jun Yuan;
Gang Li;
Liang Wang;
Jian-Ping Deng;
Qi Wang;
Ru-Meng Ma

Publication type:

Article

Gossypol Exhibits a Strong Influence Towards UDP-Glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-Mediated Metabolism of Xenobiotics and Endogenous Substances.

Published in:

Molecules, 2012, v. 17, n. 5, p. 4896, doi. 10.3390/molecules17054896

By:

Yong-Sheng Zhang;
Jun Yuan;
Zhong-Ze Fang;
Yan-Yang Tu;
Cui-Min Hu;
Gan Li;
Liang Wang;
Jian-Ping Deng;
Jia-Jiu Yao;
Hai-Rong Li

Publication type:

Article

Effect of Efavirenz on UDP-Glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 Activities in Human Liver Microsomes.

Published in:

Molecules, 2012, v. 17, n. 1, p. 851, doi. 10.3390/molecules17010851

By:

Hye Young Ji;
Hyeri Lee;
Sae Rom Lim;
Jeong Han Kim;
Hye Suk Lee

Publication type:

Article