Works matching DE "GLUCURONOSYLTRANSFERASE"

Results: 518

Caution with PBPK Modeling Based on the In Vitro Kinetics for Bilirubin Hepatic Uptake and Glucuronidation: Commentary on Dong et al.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 2, p. 301, doi. 10.1002/cpt.3734

By:

Miners, John O.;
Polasek, Thomas M.

Publication type:

Article

Inhibition of OATP1B1/3 Rather Than UGT1A1 May Be the Major Cause of the Bilirubin Elevation After Atazanavir Administration.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 2, p. 497, doi. 10.1002/cpt.3529

By:

Dong, Jin;
Sharma, Pradeep;
Emara, Rasha;
Cheung, Derek;
Tang, Weifeng;
Zhou, Diansong;
Boulton, David W.;
Någård, Mats;
Park, Miki S.

Publication type:

Article

Efficient production of hydroxysalidroside in Escherichia coli via enhanced glycosylation and semi-rational design of UGT85A1.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 638, doi. 10.1016/j.synbio.2025.03.002

By:

Xinru Wang;
Lian Wang;
Qihang Chen;
Ke Wang;
Huijing Wang;
Dong Li;
Song Gao;
Weizhu Zeng;
Jingwen Zhou

Publication type:

Article

A Rare Case of Possible Crigler–Najjar Syndrome Type 2.

Published in:

2025

By:

Chavan, Sanjay;
Verma, Sarnya;
Malwade, Sudhir;
Mane, Shailaja;
Maheshwari, Abhinav

Publication type:

Case Study

UGT1A polymorphisms as genetic biomarkers for hepatocellular carcinoma risk in Caucasian population.

Published in:

Liver International, 2017, v. 37, n. 9, p. 1345, doi. 10.1111/liv.13411

By:

De Mattia, Elena;
Cecchin, Erika;
Polesel, Jerry;
Lupo, Francesco;
Tiribelli, Claudio;
Crovatto, Marina;
Buonadonna, Angela;
Toffoli, Giuseppe

Publication type:

Article

Restriction fragment length polymorphism effectively identifies exon 1 mutation of UGT1A1 gene in patients with Gilbert's Syndrome.

Published in:

Liver International, 2015, v. 35, n. 8, p. 2050, doi. 10.1111/liv.12785

By:

Shiu, Tzu ‐ Yue;
Huang, Hsin ‐ Hung;
Lin, Hsuan ‐ Hwai;
Shih, Yu ‐ Lueng;
Chu, Heng ‐ Cheng;
Chang, Wei ‐ Kuo;
Hsieh, Tsai ‐ Yuan

Publication type:

Article

Is capillary electrophoresis on microchip devices able to genotype uridine diphosphate glucuronosyltransferase 1A1 TATA-box polymorphisms?

Published in:

Journal of Separation Science, 2014, v. 37, n. 12, p. 1521, doi. 10.1002/jssc.201400235

By:

Minucci, Angelo;
Canu, Giulia;
De Bonis, Maria;
Delibato, Elisabetta;
Capoluongo, Ettore

Publication type:

Article

UDP-glucuronosyl-transférase 1A1 et pharmacogénétique de l’irinotécan.

Published in:

Oncologie (Tech Science Press), 2005, v. 7, n. 1, p. 49, doi. 10.1007/s10269-005-0152-x

By:

Puisset, F.;
Chatelut, E.

Publication type:

Article

A Phase I Study of Infusional 5-Fluorouracil, Leucovorin, Oxaliplatin and Irinotecan in Japanese Patients with Advanced Colorectal Cancer Who Harbor UGT1A11/1,1/6 or 1/28.

Published in:

Oncology, 2012, v. 82, n. 4, p. 242, doi. 10.1159/000337225

By:

Sunakawa, Yu;
Fujita, Ken-ichi;
Ichikawa, Wataru;
Ishida, Hiroo;
Yamashita, Keishi;
Araki, Kazuhiro;
Miwa, Keisuke;
Kawara, Kaori;
Akiyama, Yuko;
Yamamoto, Wataru;
Nagashima, Fumio;
Saji, Shigehira;
Sasaki, Yasutsuna

Publication type:

Article

Molecular basis for acceptor substrate specificity of the human {beta}1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively.

Published in:

Glycobiology, 2007, v. 17, n. 8, p. 857, doi. 10.1093/glycob/cwm055

By:

Magali Fondeur-Gelinotte;
Virginie Lattard;
Sandrine Gulberti;
Rafael Oriol;
Guillermo Mulliert;
Michael WH Coughtrie;
Jacques Magdalou;
Patrick Netter;
Mohamed Ouzzine;
Sylvie Fournel-Gigleux

Publication type:

Article

Tocilizumab-induced hyperbilirubinemia in Japanese patients with rheumatoid arthritis: its association with UDP glucuronosyltransferase 1A1 gene polymorphisms.

Published in:

Modern Rheumatology, 2012, v. 22, n. 4, p. 515, doi. 10.3109/s10165-011-0537-1

By:

Mori, Shunsuke;
Terada, Kaoru;
Ueki, Yukitaka

Publication type:

Article

Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06343

By:

Aoshima, Naoya;
Fujie, Yoshiko;
Itoh, Tomoo;
Tukey, Robert H.;
Fujiwara, Ryoichi

Publication type:

Article

Soybean greatly reduces valproic acid plasma concentrations: A food-drug interaction study.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04362

By:

Marahatta, Anu;
Bhandary, Bidur;
Seul-Ki Jeong;
Hyung-Ryong Kim;
Han-Jung Chae

Publication type:

Article

Soybean greatly reduces valproic acid plasma concentrations: A food-drug interaction study.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04362

By:

Anu Marahatta;
Bidur Bhandary;
Seul-Ki Jeong;
Hyung-Ryong Kim;
Han-Jung Chae

Publication type:

Article

Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02903

By:

Ayako Shibuya;
Tomoo Itoh;
Tukey, Robert H.;
Ryoichi Fujiwara

Publication type:

Article

Drug- and Drug Abuse-Associated Hyperbilirubinemia: Experience With Atazanavir.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 2, p. 140, doi. 10.1002/cpdd.314

By:

Roy‐Chowdhury, Jayanta;
Roy‐Chowdhury, Namita;
Listowsky, Irving;
Wolkoff, Allan W.

Publication type:

Article

Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00984

By:

Liu, Xia-Wen;
Rong, Yi;
Zhang, Xing-Fei;
Huang, Jun-Jun;
Cai, Yi;
Huang, Bi-Yun;
Zhu, Liu;
Wu, Bo;
Hou, Ning;
Luo, Cheng-Feng

Publication type:

Article

Molecular Mechanism of the UDP-Glucuronosyltransferase 2B20-like Gene (AccUGT2B20-like) in Pesticide Resistance of Apis cerana cerana.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.592595

By:

Cui, Xuepei;
Wang, Chen;
Wang, Xinxin;
Li, Guilin;
Liu, Zhenguo;
Wang, Hongfang;
Guo, Xingqi;
Xu, Baohua

Publication type:

Article

Effects of rifampin and mefenamic acid on the pharmacokinetics and pharmacodynamics of dapagliflozin.

Published in:

Diabetes, Obesity & Metabolism, 2013, v. 15, n. 3, p. 280, doi. 10.1111/dom.12024

By:

Kasichayanula, S.;
Liu, X.;
Griffen, S. C.;
LaCreta, F. P.;
Boulton, D. W.

Publication type:

Article

Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug–drug interactions involving canine cytochrome P‐450, UDP‐glucuronosyltransferase, and P‐glycoprotein.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 1, p. 1, doi. 10.1111/jvp.13403

By:

Court, Michael H.;
Mealey, Katrina L.;
Burke, Neal S.;
Jimenez, Tania Perez;
Zhu, Zhaohui;
Wakshlag, Joseph J.

Publication type:

Article

Blick nach Asien.

Published in:

Nachrichten aus der Chemie, 2021, v. 69, n. 3, p. 30, doi. 10.1002/nadc.20214108738

By:

Schmid, Rolf

Publication type:

Article

X-linked ichthyosis and Crigler-Najjar syndrome?: Coexistence in a male patient with two copy number variable regions of 2q37.1 and Xp22.3.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1135, doi. 10.3892/mmr.2015.4674

By:

JINLI BAI;
YUJIN QU;
YANYAN CAO;
YAN LI;
WENHUI ZHANG;
YUWEI JIN;
HONG WANG;
FANG SONG

Publication type:

Article

Variability in the UDP-glucuronosyltransferase 1A1 (UGT1A1) promotor in a HIV-infected Portuguese population.

Published in:

Annals of Medicine, 2019, v. 51, p. 83, doi. 10.1080/07853890.2018.1561724

By:

Ferraz, Adriana;
Moscovciuc, Alina;
Fernandes, Ana;
Cruz, João Paulo;
Bandarra, Susana;
Mascarenhas, Paulo;
Martins, Rui;
Barahona, Isabel;
Ribeiro, Ana Clara

Publication type:

Article

Bilirubin concentrations in thalassemia heterozygotes in university students.

Published in:

European Journal of Haematology, 2011, v. 86, n. 4, p. 317, doi. 10.1111/j.1600-0609.2011.01578.x

By:

Huang, Yang-Yang;
Huang, May-Jen;
Wang, Hai-Lung;
Chan, Cung-Cuan;
Huang, Ching-Shan

Publication type:

Article

Association between promoter and coding region mutations of UDP-glucuronosyltransferase 1A1 and β-thalassemia/Hb E with cholelithiasis.

Published in:

European Journal of Haematology, 2008, v. 80, n. 4, p. 351, doi. 10.1111/j.1600-0609.2007.01010.x

By:

Tankanitlert, Jeeranut;
Morales, Noppawan P.;
Fucharoen, Pranee;
Fucharoen, Suthat;
Chantharaksri, Udom

Publication type:

Article

Influence of UDP-Glucuronosyltransferase Polymorphisms on Stable Warfarin Doses in Patients with Mechanical Cardiac Valves.

Published in:

Cardiovascular Therapeutics, 2015, v. 33, n. 6, p. 324, doi. 10.1111/1755-5922.12147

By:

An, Sook Hee;
Chang, Byung Chul;
Lee, Kyung Eun;
Gwak, Hye Sun

Publication type:

Article

Genetic Factors Influencing Severe Atazanavir- Associated Hyperbilirubinemia in a Population with Low UDP-Glucuronosyltransferase 1A1*28 Allele Frequency.

Published in:

Clinical Infectious Diseases, 2010, v. 51, n. 1, p. 101, doi. 10.1086/653427

By:

Wan Beom Park;
Pyoeng Gyun Choe;
Kyoung-Ho Song;
Jae Hyun Jeon;
Sang Won Park;
Hong Bin Kim;
Nam Joong Kim;
Myoung-don Oh;
Kang Won Choe

Publication type:

Article

Atazanavir Modestly Increases Plasma Levels of Raltegravir in Healthy Subjects.

Published in:

Clinical Infectious Diseases, 2008, v. 47, n. 1, p. 137, doi. 10.1086/588794

By:

Iwamoto, Marian;
Wenning, Larissa A.;
Mistry, Goutam C.;
Petry, Amelia S.;
Liou, Sarah Y.;
Ghosh, Kaylan;
Breidinger, Sheila;
Azrolan, Neal;
Gutierrez, Maria J.;
Bridson, William E.;
Stone, Julie A.;
Gottesdiener, Keith M.;
Wagner, John A.

Publication type:

Article

Suppression of hyaluronan synthesis attenuates the tumorigenicity of low‐grade chondrosarcoma.

Published in:

Journal of Orthopaedic Research, 2018, v. 36, n. 6, p. 1573, doi. 10.1002/jor.23794

By:

Hamada, Shunsuke;
Nishida, Yoshihiro;
Ikuta, Kunihiro;
Arai, Eisuke;
Koike, Hiroshi;
Ishiguro, Naoki;
Zhuo, Lisheng;
Kimata, Koji;
Ushida, Takahiro;
Shinomura, Tamayuki

Publication type:

Article

Fluid intake, genetic variants of UDP-glucuronosyltransferases, and bladder cancer risk.

Published in:

British Journal of Cancer, 2013, v. 108, n. 11, p. 2372, doi. 10.1038/bjc.2013.190

By:

Wang, J;
Wu, X;
Kamat, A;
Barton Grossman, H;
Dinney, C P;
Lin, J

Publication type:

Article

UDP-Glucuronosyltransferase 1A7 Genetic Polymorphisms Are Associated with Hepatocellular Carcinoma Risk and Onset Age.

Published in:

American Journal of Gastroenterology (Springer Nature), 2005, v. 100, n. 8, p. 1758, doi. 10.1111/j.1572-0241.2005.41857.x

By:

Chien-Sen Tseng;
Kung-Sheng Tang;
Hoi-Wan Lo;
Chen-Guo Ker;
Hsiu-Chen Teng;
Ching-Shan Huang

Publication type:

Article

Correlation of Mutational Analysis to Clinical Features in Taiwanese Patients With Gilbert's Syndrome.

Published in:

American Journal of Gastroenterology (Springer Nature), 2001, v. 96, n. 4, p. 1188, doi. 10.1111/j.1572-0241.2001.03699.x

By:

Hsieh, S.-Y.;
Wu, Y.-H.;
Lin, D.-Y.;
Chu, C.-M.;
Wu, M.;
Liaw, Y.-F.

Publication type:

Article

Prolonged Newborn Jaundice and Gilbert's Disease.

Published in:

American Journal of Gastroenterology (Springer Nature), 1999, v. 94, n. 9, p. 2343, doi. 10.1111/j.1572-0241.1999.02343.x

By:

Mack, D. R.;
Thompson, Jon S.

Publication type:

Article

Mutation of UGT1A1 Gene in a Case of Crigler-Najjar Syndrome Type II.

Published in:

1999

By:

Ishihara, Tomoaki;
Sato, Hiroshi;
Fukui, Susumu;
Kagawa, Keizo;
Kaito, Masahiko;
Gabazza, Esteban C.;
Adachi, Yukihiko

Publication type:

Letter

Impact of UGT1A1 gene polymorphisms on plasma dolutegravir trough concentrations and neuropsychiatric adverse events in Japanese individuals infected with HIV-1.

Published in:

2017

By:

Hiroki Yagura;
Dai Watanabe;
Hiroyuki Kushida;
Kosuke Tomishima;
Hiroaki Togami;
Atsushi Hirano;
Masaaki Takahashi;
Kazuyuki Hirota;
Motoko Ikuma;
Daisuke Kasai;
Yasuharu Nishida;
Munehiro Yoshino;
Kunio Yamazaki;
Tomoko Uehira;
Takuma Shirasaka;
Yagura, Hiroki;
Watanabe, Dai;
Kushida, Hiroyuki;
Tomishima, Kosuke;
Togami, Hiroaki

Publication type:

journal article

Common variants in glucuronidation enzymes and membrane transporters as potential risk factors for colorectal cancer: a case control study.

Published in:

2017

By:

Falkowski, Sabrina;
Woillard, Jean-Baptiste;
Postil, Deborah;
Tubiana-Mathieu, Nicole;
Terrebonne, Eric;
Pariente, Antoine;
Smith, Denis;
Guimbaud, Rosine;
Thalamas, Claire;
Rouguieg-Malki, Koukeb;
Marquet, Pierre;
Picard, Nicolas

Publication type:

journal article

The draft genome of whitefly Bemisia tabaci MEAM1, a global crop pest, provides novel insights into virus transmission, host adaptation, and insecticide resistance.

Published in:

BMC Biology, 2016, v. 14, p. 1, doi. 10.1186/s12915-016-0321-y

By:

Wenbo Chen;
Hasegawa, Daniel K.;
Kaur, Navneet;
Kliot, Adi;
Pinheiro, Patricia Valle;
Junbo Luan;
Stensmyr, Marcus C.;
Yi Zheng;
Wenli Liu;
Honghe Sun;
Yimin Xu;
Yuan Luo;
Kruse, Angela;
Xiaowei Yang;
Kontsedalov, Svetlana;
Lebedev, Galina;
Fisher, Tonja W.;
Nelson, David R.;
Hunter, Wayne B.;
Brown, Judith K.

Publication type:

Article

Chemo‐Enzymatic Synthesis of Long‐Chain Oligosaccharides for Studying Xylan‐Modifying Enzymes.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202203941

By:

Álvarez‐Martínez, Ignacio;
Ruprecht, Colin;
Senf, Deborah;
Wang, Hsin‐tzu;
Urbanowicz, Breeanna R.;
Pfrengle, Fabian

Publication type:

Article

A Molecular‐Splicing Strategy for Constructing a Near‐Infrared Fluorescent Probe for UDP‐Glucuronosyltransferase 1A1.

Published in:

Angewandte Chemie, 2021, v. 133, n. 46, p. 24771, doi. 10.1002/ange.202109479

By:

Tian, Xiangge;
Liu, Tao;
Ma, Yinhua;
Gao, Jian;
Feng, Lei;
Cui, Jingnan;
James, Tony D.;
Ma, Xiaochi

Publication type:

Article

Lipid-activated transcription factors control bile acid glucuronidation.

Published in:

Molecular & Cellular Biochemistry, 2009, v. 326, n. 1/2, p. 3, doi. 10.1007/s11010-008-0001-5

By:

Olivier Barbier;
Jocelyn Trottier;
Jenny Kaeding;
Patrick Caron;
Mélanie Verreault

Publication type:

Article

Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2002, v. 17, n. 5, p. 233, doi. 10.1002/hup.403

By:

Linnet, Kristian

Publication type:

Article

Di- myo-inositol phosphate and novel UDP-sugars accumulate in the extreme hyperthermophile Pyrolobus fumarii.

Published in:

Extremophiles, 2008, v. 12, n. 3, p. 383, doi. 10.1007/s00792-008-0143-0

By:

Gonçalves, Luís G.;
Lamosa, Pedro;
Huber, Robert;
Santos, Helena

Publication type:

Article

Contribution of UDP-glucuronosyltransferases 1A9 and 2B7 to the glucuronidation of indomethacin in the human liver.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 3, p. 289, doi. 10.1007/s00228-007-0261-0

By:

Mano, Yuji;
Usui, Takashi;
Kamimura, Hidetaka

Publication type:

Article

Inhibitory potential of nonsteroidal anti-inflammatory drugs on UDP-glucuronosyltransferase 2B7 in human liver microsomes.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 2, p. 211, doi. 10.1007/s00228-006-0241-9

By:

Mano, Yuji;
Usui, Takashi;
Kamimura, Hidetaka

Publication type:

Article

UGT1A polymorphisms in a Swedish cohort and a human diversity panel, and the relation to bilirubin plasma levels in males and females.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 10, p. 829, doi. 10.1007/s00228-006-0166-3

By:

Odeberg, J. Mercke;
Andrade, J.;
Holmberg, K.;
Hoglund, P.;
Malmqvist, U.;
Odeberg, J.

Publication type:

Article

A pharmacokinetic study of paracetamol in Thai β-thalassemia/HbE patients.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 9, p. 743, doi. 10.1007/s00228-006-0167-2

By:

Tankanitlert, Jeeranut;
Howard, Thad A.;
Temsakulphong, Anusorn;
Sirankapracha, Pornpan;
Morales, Noppawan;
Sanvarinda, Yupin;
Fucharoen, Pranee;
Ware, Russell E.;
Fucharoen, Suthat;
Chantharaksri, Udom

Publication type:

Article

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy.

Published in:

European Journal of Clinical Pharmacology, 2002, v. 58, n. 5, p. 353, doi. 10.1007/s00228-002-0490-1

By:

Holthe, Monica;
Klepstad, Pål;
Zahlsen, Kolbjørn;
Borchgrevink, Petter C.;
Hagen, Lars;
Dale, Ola;
Kaasa, Stein;
Krokan, Hans E.;
Skorpen, Frank

Publication type:

Article

Effect of a conserved mutation in uridine diphosphate glucuronosyltransferase 1A1 and 1A6 on glucuronidation of a metabolite of flutamide.

Published in:

European Journal of Clinical Pharmacology, 2002, v. 58, n. 1, p. 11, doi. 10.1007/s00228-001-0417-2

By:

Ito, Masaki;
Yamamoto, Kazuo;
Maruo, Yoshihiro;
Sato, Hiroshi;
Fujiyama, Yoshihide;
Bamba, Tadao

Publication type:

Article

Inhibitory effect of troglitazone on glucuronidation catalyzed by human uridine diphosphate-glucuronosyltransferase 1A6.

Published in:

European Journal of Clinical Pharmacology, 2001, v. 56, n. 12, p. 893, doi. 10.1007/s002280000252

By:

Ito, Masaki;
Yamamoto, Kazuo;
Sato, Hiroshi;
Fujiyama, Yoshihide;
Bamba, Tadao

Publication type:

Article

Mycophenolic acid glucuronidation and its inhibition by non-steroidal anti-inflammatory drugs in human liver and kidney.

Published in:

European Journal of Clinical Pharmacology, 2000, v. 56, n. 9/10, p. 659, doi. 10.1007/s002280000227

By:

Vietri, M.;
Pietrabissa, A.;
Mosca, F.;
Pacifici, G.M.

Publication type:

Article