Works matching DE "GLUCURONIDATION"

Results: 310

Morphine Metabolism in Human Skin Microsomes.

Published in:

Skin Pharmacology & Physiology, 2012, v. 25, n. 6, p. 319, doi. 10.1159/000342067

By:

Heilmann, S.;
Küchler, S.;
Schäfer-Korting, M.

Publication type:

Article

Mechanism of dasabuvir inhibition of acetaminophen glucuronidation.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 1, p. 131, doi. 10.1093/jpp/rgab144

By:

Zhang, Qingchen;
Duan, Su Xiang;
Harmatz, Jerold S;
Wei, Zixuan;
Singleton, Christopher A;
Greenblatt, David J

Publication type:

Article

Identification of human uridine diphosphateglucuronosyltransferase isoforms responsible for the glucuronidation of 10,11-dihydro-10-hydroxy-carbazepine.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 3, p. 388, doi. 10.1093/jpp/rgaa059

By:

Kai Huang;
Linling Que;
Ying Ding;
Nannan Chu;
Zhenzhong Qian;
Wei Qin;
Yuanxing Chen;
Jisheng Zhang;
Qing He

Publication type:

Article

Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 12, p. 1865, doi. 10.1111/jphp.13337

By:

Xing, Han;
Yang, Jing;
Ren, Kaidi;
Qin, Zifei;
Wang, Peile;
Zhang, Xiaojian;
Yao, Zhihong;
Gonzalez, Frank J.;
Yao, Xinsheng

Publication type:

Article

Characterization of metabolic activity, isozyme contribution and species differences of bavachin, and identification of efflux transporters for bavachin‐O‐glucuronide in HeLa1A1 cells.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 12, p. 1771, doi. 10.1111/jphp.13324

By:

Li, Yang;
Xu, Chunxia;
Xu, Jinjin;
Qin, Zifei;
Li, Shishi;
Hu, Liufang;
Yao, Zhihong;
Gonzalez, Frank J.;
Yao, Xinsheng

Publication type:

Article

Glucuronidation and its effect on the bioactivity of amentoflavone, a biflavonoid from Ginkgo biloba leaves.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 12, p. 1840, doi. 10.1111/jphp.13247

By:

Gan, Lili;
Ma, Jiating;
You, Guoquan;
Mai, Jinxia;
Wang, Zhaoyu;
Yang, Ruopeng;
Xie, Cong;
Fei, Jingrao;
Tang, Lan;
Zhao, Jie;
Cai, Zheng;
Ye, Ling

Publication type:

Article

Resveratrol glucuronidation in vitro: potential implications of inhibition by probenecid.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 3, p. 371, doi. 10.1111/jphp.13037

By:

Matin, Bahar;
Sherbini, Ahmad A.;
Alam, Novera;
Harmatz, Jerold S.;
Greenblatt, David J.

Publication type:

Article

Identification and characterization of human UDP-glucuronosyltransferases responsible for the in-vitro glucuronidation of arctigenin.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 12, p. 1673, doi. 10.1111/jphp.12483

By:

Xin, Hong;
Xia, Yang‐Liu;
Hou, Jie;
Wang, Ping;
He, Wei;
Yang, Ling;
Ge, Guang‐Bo;
Xu, Wei

Publication type:

Article

Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1 A9 and UGT2 B7.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 4, p. 583, doi. 10.1111/jphp.12351

By:

Wu, Zhufeng;
Liu, Hongming;
Wu, Baojian

Publication type:

Article

Coexistence of Gilbert Syndrome and Hereditary Spherocytosis in a Child Presenting with Extreme Jaundice.

Published in:

2014

By:

Jae Hee Lee;
Kyung Rye Moon

Publication type:

Case Study

Safety of butylated hydroxy anisole (BHA) for all animal species.

Published in:

EFSA Journal, 2019, v. 17, n. 12, p. N.PAG, doi. 10.2903/j.efsa.2019.5913

By:

Bampidis, Vasileios;
Azimonti, Giovanna;
Bastos, Maria de Lourdes;
Christensen, Henrik;
Dusemund, Birgit;
Kouba, Maryline;
Kos Durjava, Mojca;
López‐Alonso, Marta;
López Puente, Secundino;
Marcon, Francesca;
Mayo, Baltasar;
Pechová, Alena;
Petkova, Mariana;
Ramos, Fernando;
Sanz, Yolanda;
Villa, Roberto Edoardo;
Woutersen, Ruud;
Aquilina, Gabriele;
Bories, Georges;
Gropp, Jürgen

Publication type:

Article

Structure and Protein-Protein Interactions of Human UDP-Glucuronosyltransferases.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00388

By:

Ryoichi Fujiwara;
Tsuyoshi Yokoi;
Miki Nakajima

Publication type:

Article

Induction of morphine-6-glucuronide synthesis by heroin self-administration in the rat.

Published in:

Psychopharmacology, 2012, v. 221, n. 2, p. 195, doi. 10.1007/s00213-011-2534-7

By:

Meringolo, Maria;
Brusadin, Valentina;
Luca, Maria;
Montanari, Christian;
Antonilli, Letizia;
Nencini, Paolo;
Badiani, Aldo

Publication type:

Article

Systematic screening and characterization of cardamonin metabolites using UHPLC-Q-Exactive Orbitrap MS after oral administration to rats.

Published in:

Arabian Journal of Chemistry, 2020, v. 13, n. 12, p. 8768, doi. 10.1016/j.arabjc.2020.10.007

By:

Dong, Fan;
Wang, Shaoping;
Yang, Ailin;
Li, Qiyan;
Wang, Yuqi;
Dai, Long;
Tao, Yufan;
Wei, Xia;
Zhang, Jiayu

Publication type:

Article

Bisphenol-A and phthalate metabolism in children with neurodevelopmental disorders.

Published in:

PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0289841

By:

Stein, T. Peter;
Schluter, Margaret D.;
Steer, Robert A.;
Ming, Xue

Publication type:

Article

Effect of UDP-Glucuronosyltransferase (UGT) 1A Polymorphism (rs8330 and rs10929303) on Glucuronidation Status of Acetaminophen.

Published in:

Dose-Response, 2017, v. 15, n. 3, p. 1, doi. 10.1177/1559325817723731

By:

Mehboob, Huma;
Tahir, Imtiaz Mahmood;
Tahiral, Tahira;
Saleem, Sadaf;
Perveen, Sofia;
Farooqi, Aboubakker

Publication type:

Article

Antiepileptic drug treatment in pregnancy: Changes in drug disposition and their clinical implications.

Published in:

Epilepsia (Series 4), 2013, v. 54, n. 3, p. 405, doi. 10.1111/epi.12109

By:

Tomson, Torbjörn;
Landmark, Cecilie Johannessen;
Battino, Dina

Publication type:

Article

Thyroid Hormone-disrupting Effects and the Amphibian Metamorphosis Assay.

Published in:

Journal of Toxicologic Pathology, 2012, v. 25, n. 1, p. 1, doi. 10.1293/tox.25.1

By:

Miyata, Kaori;
Ose, Keiko

Publication type:

Article

Analysis of In Vivo Existence Forms of Nardosinone in Mice by UHPLC-Q-TOF-MS Technique.

Published in:

Molecules, 2022, v. 27, n. 21, p. 7267, doi. 10.3390/molecules27217267

By:

Zhang, Jing;
Lv, Yang;
Bai, Yu-Sha;
Li, Meng-Yuan;
Wang, Shun-Qi;
Wang, Li-Li;
Liu, Guang-Xue;
Xu, Feng;
Shang, Ming-Ying;
Cai, Shao-Qing

Publication type:

Article

UGT1A1 and UGT1A9 Are Responsible for Phase II Metabolism of Tectorigenin and Irigenin In Vitro.

Published in:

Molecules, 2022, v. 27, n. 13, p. 4104, doi. 10.3390/molecules27134104

By:

Li, Ji;
Xu, Zhangyao;
Gu, Jifeng

Publication type:

Article

Metabolite Identification of a Novel Anti-Leishmanial Agent OJT007 in Rat Liver Microsomes Using LC-MS/MS.

Published in:

Molecules, 2022, v. 27, n. 9, p. 2854, doi. 10.3390/molecules27092854

By:

Rincon Nigro, Maria Eugenia;
Du, Ting;
Gao, Song;
Kaur, Manvir;
Xie, Huan;
Olaleye, Omonike Arike;
Liang, Dong

Publication type:

Article

Potential Assessment of UGT2B17 Inhibition by Salicylic Acid in Human Supersomes In Vitro.

Published in:

Molecules, 2021, v. 26, n. 15, p. 4410, doi. 10.3390/molecules26154410

By:

Salhab, Hassan;
Naughton, Declan P.;
Barker, James

Publication type:

Article

Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5170, doi. 10.3390/molecules25215170

By:

Lin, Chu-Hung;
Chou, Hsiao-Jung;
Chang, Chih-Chi;
Chen, Ih-Sheng;
Chang, Hsun-Shuo;
Cheng, Tian-Lu;
Kuo, Yueh-Hsiung;
Ko, Horng-Huey;
Fabiani, Roberto;
Pereira, Eliana

Publication type:

Article

Metabolism and Pharmacokinetics of SP-8356, a Novel (1S)-(−)-Verbenone Derivative, in Rats and Dogs and Its Implications in Humans.

Published in:

Molecules, 2020, v. 25, n. 8, p. 1775, doi. 10.3390/molecules25081775

By:

Zhou, Yuanyuan;
Oh, Mun Hwan;
Kim, Yeon Joon;
Kim, Eun-yeong;
Kang, Jinhong;
Chung, Sung;
Ju, Chung;
Kim, Won-Ki;
Lee, Kiho

Publication type:

Article

An Investigation on Glucuronidation Metabolite Identification, Isozyme Contribution, and Species Differences of GL-V9 In Vitro and In Vivo.

Published in:

Molecules, 2019, v. 24, n. 8, p. 1576, doi. 10.3390/molecules24081576

By:

Xing, Han;
Kong, Dexuan;
Ning, Chen;
Kong, Ying;
Ren, Chang;
Cheng, Yujie;
Cai, Hui;
Wang, Jubo;
Zhao, Di;
Li, Ning;
Chen, Xijing;
Li, Zhiyu;
Lu, Yang

Publication type:

Article

Dual Effect of Glucuronidation of a Pyrogallol-Type Phytophenol Antioxidant: A Comparison between Scutellarein and Scutellarin.

Published in:

Molecules, 2018, v. 23, n. 12, p. 3225, doi. 10.3390/molecules23123225

By:

Liu, Qianru;
Li, Xican;
Ouyang, Xiaojian;
Chen, Dongfeng;
Cardoso, Susana M.;
Fazio, Alessia

Publication type:

Article

Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents.

Published in:

Molecules, 2018, v. 23, n. 10, p. 2696, doi. 10.3390/molecules23102696

By:

Abdullah, Nurul Huda;
Ismail, Sabariah

Publication type:

Article

Characterization of the In Vivo and In Vitro Metabolites of Linarin in Rat Biosamples and Intestinal Flora Using Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry.

Published in:

Molecules, 2018, v. 23, n. 9, p. 2140, doi. 10.3390/molecules23092140

By:

Xinchi Feng;
Yang Li;
Chenxi Guang;
Miao Qiao;
Tong Wang;
Liwei Chai;
Feng Qiu

Publication type:

Article

UPLC-QTOF-MS Identification of the Chemical Constituents in Rat Plasma and Urine after Oral Administration of Rubia cordifolia L. Extract.

Published in:

Molecules, 2017, v. 22, n. 8, p. 1327, doi. 10.3390/molecules22081327

By:

Zuoliang Zheng;
Shengqing Li;
Yuping Zhong;
Ruoting Zhan;
Yan Yan;
Huafeng Pan;
Ping Yan

Publication type:

Article

Inhibitory Effects of Diclofenac on Steroid Glucuronidation In Vivo Do Not Affect Hair-Based Doping Tests for Stanozolol.

Published in:

Molecules, 2017, v. 22, n. 6, p. 976, doi. 10.3390/molecules22060976

By:

Zachár, Gergely;
Deshmukh, Naved I. K.;
Petróczi, Andrea;
Székely, Andrea D.;
Shah, Iltaf;
Barker, James;
Naughton, Declan P.

Publication type:

Article

In Vitro Glucuronidation and Sulfation of ε-Viniferin, a Resveratrol Dimer, in Humans and Rats.

Published in:

Molecules, 2017, v. 22, n. 5, p. 733, doi. 10.3390/molecules22050733

By:

Courtois, Arnaud;
Jourdes, Michael;
Dupin, Adeline;
Lapèze, Caroline;
Renouf, Elodie;
Biais, Benoît;
Teissedre, Pierre-Louis;
Mérillon, Jean-Michel;
Richard, Tristan;
Krisa, Stéphanie

Publication type:

Article

Multiple UDP-Glucuronosyltransferase and Sulfotransferase Enzymes are Responsible for the Metabolism of Verproside in Human Liver Preparations.

Published in:

Molecules, 2017, v. 22, n. 4, p. 670, doi. 10.3390/molecules22040670

By:

Ju-Hyun Kim;
Deok-Kyu Hwang;
Ju-Yeon Moon;
Yongnam Lee;
Ji Seok Yoo;
Dae Hee Shin;
Hye Suk Lee

Publication type:

Article

In Vivo Metabolite Profiling of a Purified Ellagitannin Isolated from Polygonum capitatum in Rats.

Published in:

Molecules, 2016, v. 21, n. 9, p. 1110, doi. 10.3390/molecules21091110

By:

Jing-Yi Ma;
Xuelin Zhou;
Jie Fu;
Chi-Yu He;
Ru Feng;
Min Huang;
Jia-Wen Shou;
Zhen-Xiong Zhao;
Xiao-Yang Li;
Luye Zhang;
Yang-Chao Chen;
Yan Wang

Publication type:

Article

In Vitro and in Vivo Metabolism of Verproside in Rats.

Published in:

Molecules, 2012, v. 17, n. 10, p. 11990, doi. 10.3390/molecules171011990

By:

Min Gi Kim;
Deok-Kyu Hwang;
Hyeon-Uk Jeong;
Hye Young Ji;
Sei-Ryang Oh;
Hye Suk Lee;
Dae Hee Shin;
Ji Seok Yoo;
Yongnam Lee

Publication type:

Article

The Fusarium metabolite culmorin suppresses the in vitro glucuronidation of deoxynivalenol.

Published in:

Archives of Toxicology, 2019, v. 93, n. 6, p. 1729, doi. 10.1007/s00204-019-02459-w

By:

Woelflingseder, Lydia;
Warth, Benedikt;
Vierheilig, Immina;
Schwartz-Zimmermann, Heidi;
Hametner, Christian;
Nagl, Veronika;
Novak, Barbara;
Šarkanj, Bojan;
Berthiller, Franz;
Adam, Gerhard;
Marko, Doris

Publication type:

Article

Correlations between metabolism and structural elements of the alicyclic fentanyl analogs cyclopropyl fentanyl, cyclobutyl fentanyl, cyclopentyl fentanyl, cyclohexyl fentanyl and 2,2,3,3-tetramethylcyclopropyl fentanyl studied by human hepatocytes and LC-QTOF-MS

Published in:

Archives of Toxicology, 2019, v. 93, n. 1, p. 95, doi. 10.1007/s00204-018-2330-9

By:

Åstrand, Anna;
Töreskog, Amanda;
Watanabe, Shimpei;
Kronstrand, Robert;
Gréen, Henrik;
Vikingsson, Svante

Publication type:

Article

Correction to: Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

Published in:

2018

By:

Schwartz-Zimmermann, Heidi E.;
Hametner, Christian;
Nagl, Veronika;
Fiby, Iris;
Macheiner, Lukas;
Winkler, Janine;
Dänicke, Sven;
Clark, Erica;
Pestka, James J.;
Berthiller, Franz

Publication type:

Correction Notice

Deglucosylation of zearalenone-14-glucoside in animals and human liver leads to underestimation of exposure to zearalenone in humans.

Published in:

Archives of Toxicology, 2018, v. 92, n. 9, p. 2779, doi. 10.1007/s00204-018-2267-z

By:

Yang, Shupeng;
Zhang, Huiyan;
Zhang, Jinzhen;
Li, Yanshen;
Jin, Yue;
Zhang, Suxia;
De Saeger, Sarah;
Li, Yi;
Zhou, Jinhui;
Sun, Feifei;
De Boevre, Marthe

Publication type:

Article

Regioselective glucuronidation of daidzein in liver and intestinal microsomes of humans, monkeys, rats, and mice.

Published in:

Archives of Toxicology, 2018, v. 92, n. 9, p. 2809, doi. 10.1007/s00204-018-2265-1

By:

Hanioka, Nobumitsu;
Ohkawara, Susumu;
Isobe, Takashi;
Ochi, Sadayuki;
Tanaka-Kagawa, Toshiko;
Jinno, Hideto

Publication type:

Article

Hepatic glucuronidation of 4- tert-octylphenol in humans: inter-individual variability and responsible UDP-glucuronosyltransferase isoforms.

Published in:

Archives of Toxicology, 2017, v. 91, n. 11, p. 3543, doi. 10.1007/s00204-017-1982-1

By:

Isobe, Takashi;
Ohkawara, Susumu;
Tanaka-Kagawa, Toshiko;
Jinno, Hideto;
Hanioka, Nobumitsu

Publication type:

Article

Cytochrome P450-mediated metabolism of triclosan attenuates its cytotoxicity in hepatic cells.

Published in:

Archives of Toxicology, 2017, v. 91, n. 6, p. 2405, doi. 10.1007/s00204-016-1893-6

By:

Wu, Yuanfeng;
Chitranshi, Priyanka;
Loukotková, Lucie;
Gamboa da Costa, Gonçalo;
Beland, Frederick;
Zhang, Jie;
Fang, Jia-Long

Publication type:

Article

Glucuronidation of 4- tert-octylphenol in humans, monkeys, rats, and mice: an in vitro analysis using liver and intestine microsomes.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1227, doi. 10.1007/s00204-016-1800-1

By:

Hanioka, Nobumitsu;
Isobe, Takashi;
Ohkawara, Susumu;
Tanaka-Kagawa, Toshiko;
Jinno, Hideto

Publication type:

Article

Glucuronidation of mono(2-ethylhexyl) phthalate in humans: roles of hepatic and intestinal UDP-glucuronosyltransferases.

Published in:

Archives of Toxicology, 2017, v. 91, n. 2, p. 689, doi. 10.1007/s00204-016-1708-9

By:

Hanioka, Nobumitsu;
Isobe, Takashi;
Kinashi, Yu;
Tanaka-Kagawa, Toshiko;
Jinno, Hideto

Publication type:

Article

In vivo contribution of deoxynivalenol-3-β- d-glucoside to deoxynivalenol exposure in broiler chickens and pigs: oral bioavailability, hydrolysis and toxicokinetics.

Published in:

Archives of Toxicology, 2017, v. 91, n. 2, p. 699, doi. 10.1007/s00204-016-1710-2

By:

Broekaert, Nathan;
Croubels, Siska;
Devreese, Mathias;
van Bergen, Thomas;
Schauvliege, Stijn;
De Boevre, Marthe;
De Saeger, Sarah;
Vermeulen, An;
Vanhaecke, Lynn;
Berthiller, Franz;
Malachová, Alexandra;
Michlmayr, Herbert;
Adam, Gerhard

Publication type:

Article

Hepatic and intestinal glucuronidation of mono(2-ethylhexyl) phthalate, an active metabolite of di(2-ethylhexyl) phthalate, in humans, dogs, rats, and mice: an in vitro analysis using microsomal fractions.

Published in:

Archives of Toxicology, 2016, v. 90, n. 7, p. 1651, doi. 10.1007/s00204-015-1619-1

By:

Hanioka, Nobumitsu;
Isobe, Takashi;
Kinashi, Yu;
Tanaka-Kagawa, Toshiko;
Jinno, Hideto

Publication type:

Article

Metabolism and urinary excretion kinetics of di(2-ethylhexyl) terephthalate (DEHTP) in three male volunteers after oral dosage.

Published in:

Archives of Toxicology, 2016, v. 90, n. 7, p. 1659, doi. 10.1007/s00204-016-1715-x

By:

Lessmann, Frederik;
Schütze, André;
Weiss, Tobias;
Langsch, Angelika;
Otter, Rainer;
Brüning, Thomas;
Koch, Holger

Publication type:

Article

In vitro glucuronidation kinetics of deoxynivalenol by human and animal microsomes and recombinant human UGT enzymes.

Published in:

Archives of Toxicology, 2015, v. 89, n. 6, p. 949, doi. 10.1007/s00204-014-1286-7

By:

Maul, Ronald;
Warth, Benedikt;
Schebb, Nils;
Krska, Rudolf;
Koch, Matthias;
Sulyok, Michael

Publication type:

Article

Prolonged sedation of lorazepam due to absent UGT2B4/2B7 glucuronidation.

Published in:

2014

By:

Siller, Nelly;
Egerer, Gerlinde;
Weiss, Johanna;
Mikus, Gerd

Publication type:

Letter

Mouse hepatoma cell lines differing in aryl hydrocarbon receptor-mediated signaling have different activities for glucuronidation.

Published in:

Archives of Toxicology, 2012, v. 86, n. 4, p. 643, doi. 10.1007/s00204-011-0789-8

By:

Burkhardt, B.;
Jung, S.;
Pfeiffer, E.;
Weiss, C.;
Metzler, M.

Publication type:

Article

Assessing and Optimising Several Enzymes Used for Drug Analysis in Urine.

Published in:

Multi-Knowledge Electronic Comprehensive Journal For Education & Science Publications (MECSJ), 2022, n. 56, p. 1

By:

Algethami, Fatimah Abdullah

Publication type:

Article