Works about GLUCAGON receptors

Results: 231
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    Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection.

    Published in:
    AAPS Open, 2018, v. 4, n. 1, p. 1, doi. 10.1186/s41120-018-0026-0
    By:
    • Beaumont, Maribel;
    • Tomazela, Daniela;
    • Hodges, Douglas;
    • Ermakov, Grigori;
    • Hsieh, Edward;
    • Figueroa, Isabel;
    • So, On-Yee;
    • Song, Yaoli;
    • Ma, Huiping;
    • Antonenko, Svetlana;
    • Mengesha, Wondwessen;
    • Zhang, Yi Wei;
    • Zhang, Shuli;
    • Hseih, SuChun;
    • Ayanoglu, Gulesi;
    • Du, Xiaoyan;
    • Rimmer, Eric;
    • Judo, Michael;
    • Vives, Franklin;
    • Yearley, Jennifer H.
    Publication type:
    Article
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    Safety, pharmacokinetics and pharmacodynamics of HRS‐7535, a novel oral small molecule glucagon‐like peptide‐1 receptor agonist, in healthy participants: A phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose, and food effect trial

    Published in:
    Diabetes, Obesity & Metabolism, 2024, v. 26, n. 3, p. 901, doi. 10.1111/dom.15383
    By:
    • Wu, Jingying;
    • Zhou, Renpeng;
    • Zhang, Qian;
    • Zhang, Qin;
    • Qin, Huiling;
    • Ye, Zi;
    • Xu, Yimei;
    • Feng, Sheng;
    • Shu, Chang;
    • Shen, Yu;
    • Fan, Yang;
    • Wang, Quanren;
    • Du, Yijun;
    • Hu, Wei
    Publication type:
    Article
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    Comparison of clinical efficacy and safety of weekly glucagon‐like peptide‐1 receptor agonists dulaglutide and semaglutide in Japanese patients with type 2 diabetes: Randomized, parallel‐group, multicentre, open‐label trial (COMING study)

    Published in:
    Diabetes, Obesity & Metabolism, 2023, v. 25, n. 12, p. 3632, doi. 10.1111/dom.15258
    By:
    • Kimura, Tomohiko;
    • Katakura, Yukino;
    • Shimoda, Masashi;
    • Kawasaki, Fumiko;
    • Yamabe, Mizuho;
    • Tatsumi, Fuminori;
    • Matsuki, Michihiro;
    • Iwamoto, Yuichiro;
    • Anno, Takatoshi;
    • Fushimi, Yoshiro;
    • Kamei, Shinji;
    • Kimura, Yukiko;
    • Nakanishi, Shuhei;
    • Mune, Tomoatsu;
    • Kaku, Kohei;
    • Kaneto, Hideaki
    Publication type:
    Article
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    Effects of oral semaglutide on cardiovascular outcomes in individuals with type 2 diabetes and established atherosclerotic cardiovascular disease and/or chronic kidney disease: Design and baseline characteristics of SOUL, a randomized trial.

    Published in:
    Diabetes, Obesity & Metabolism, 2023, v. 25, n. 7, p. 1932, doi. 10.1111/dom.15058
    By:
    • McGuire, Darren K.;
    • Busui, Rodica P.;
    • Deanfield, John;
    • Inzucchi, Silvio E.;
    • Mann, Johannes F. E.;
    • Marx, Nikolaus;
    • Mulvagh, Sharon L.;
    • Poulter, Neil;
    • Engelmann, Mads D. M.;
    • Hovingh, G. Kees;
    • Ripa, Maria Sejersten;
    • Gislum, Mette;
    • Brown‐Frandsen, Kirstine;
    • Buse, John B.
    Publication type:
    Article
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    Glucagon induces the hepatic expression of inflammatory markers in vitro and in vivo.

    Published in:
    Diabetes, Obesity & Metabolism, 2023, v. 25, n. 2, p. 556, doi. 10.1111/dom.14902
    By:
    • Andreozzi, Francesco;
    • Di Fatta, Concetta;
    • Spiga, Rosangela;
    • Mannino, Gaia Chiara;
    • Mancuso, Elettra;
    • Averta, Carolina;
    • De Caro, Carmen;
    • Tallarico, Martina;
    • Leo, Antonio;
    • Citraro, Rita;
    • Russo, Emilio;
    • De Sarro, Giovambattista;
    • Sesti, Giorgio
    Publication type:
    Article
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    Acute concomitant glucose‐dependent insulinotropic polypeptide receptor antagonism during glucagon‐like peptide 1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity

    Published in:
    Diabetes, Obesity & Metabolism, 2022, v. 24, n. 9, p. 1882, doi. 10.1111/dom.14736
    By:
    • Stensen, Signe;
    • Krogh, Liva L.;
    • Sparre‐Ulrich, Alexander H.;
    • Dela, Flemming;
    • Hartmann, Bolette;
    • Vilsbøll, Tina;
    • Holst, Jens J.;
    • Rosenkilde, Mette M.;
    • Christensen, Mikkel B.;
    • Gasbjerg, Lærke S.;
    • Knop, Filip K.
    Publication type:
    Article
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    Incretin combination therapy for the treatment of non‐alcoholic steatohepatitis.

    Published in:
    Diabetes, Obesity & Metabolism, 2020, v. 22, n. 8, p. 1328, doi. 10.1111/dom.14035
    By:
    • Kannt, Aimo;
    • Madsen, Andreas Nygaard;
    • Kammermeier, Claire;
    • Elvert, Ralf;
    • Klöckener, Tim;
    • Bossart, Martin;
    • Haack, Torsten;
    • Evers, Andreas;
    • Lorenz, Katrin;
    • Hennerici, Wolfgang;
    • Rocher, Corinne;
    • Böcskei, Zsolt;
    • Guillemot, Jean‐Claude;
    • Mikol, Vincent;
    • Pattou, Francois;
    • Staels, Bart;
    • Wagner, Michael
    Publication type:
    Article
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    Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates.

    Published in:
    Diabetes, Obesity & Metabolism, 2016, v. 18, n. 12, p. 1176, doi. 10.1111/dom.12735
    By:
    • Henderson, S. J.;
    • Konkar, A.;
    • Hornigold, D. C.;
    • Trevaskis, J. L.;
    • Jackson, R.;
    • Fritsch Fredin, M.;
    • Jansson‐Löfmark, R.;
    • Naylor, J.;
    • Rossi, A.;
    • Bednarek, M. A.;
    • Bhagroo, N.;
    • Salari, H.;
    • Will, S.;
    • Oldham, S.;
    • Hansen, G.;
    • Feigh, M.;
    • Klein, T.;
    • Grimsby, J.;
    • Maguire, S.;
    • Jermutus, L.
    Publication type:
    Article
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    Evidence for Glucagon Secretion and Function Within the Human Gut.

    Published in:
    Endocrinology, 2021, v. 162, n. 4, p. 1, doi. 10.1210/endocr/bqab022
    By:
    • Sun, Emily W;
    • Martin, Alyce M;
    • Fontgalland, Dayan de;
    • Sposato, Luigi;
    • Rabbitt, Philippa;
    • Hollington, Paul;
    • Wattchow, David A;
    • Colella, Alexander D;
    • Chataway, Tim;
    • Albrechtsen, Nicolai J Wewer;
    • Spencer, Nick J;
    • Young, Richard L;
    • Keating, Damien J
    Publication type:
    Article