Works matching DE "GLIOTOXIN"

Results: 46

Gliotoxin Targets Nuclear NOTCH2 in Human Solid Tumor Derived Cell Lines In Vitro and Inhibits Melanoma Growth in Xenograft Mouse Model.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00319

By:

Hubmann, Rainer;
Sieghart, Wolfgang;
Schnabl, Susanne;
Araghl, Mohammad;
Hilgarth, Martin;
Reiter, Marlies;
Demirtas, Dita;
Valent, Peter;
Zielinski, Christoph;
Jäger, Ulrich;
Shehata, Medhat

Publication type:

Article

Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity.

Published in:

Virulence, 2018, v. 9, n. 1, p. 1062, doi. 10.1080/21505594.2018.1482182

By:

Liu, Hong;
Xu, Wenjie;
Solis, Norma V.;
Woolford, Carol;
Mitchell, Aaron P.;
Filler, Scott G.

Publication type:

Article

In vitro study on aspects of molecular mechanisms underlying invasive aspergillosis caused by gliotoxin and fumagillin, alone and in combination.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71367-2

By:

Gayathri, Loganathan;
Akbarsha, Mohammad A.;
Ruckmani, Kandasamy

Publication type:

Article

Prospective evaluation of a combination of fungal biomarkers for the diagnosis of invasive fungal disease in high‐risk haematology patients.

Published in:

Mycoses, 2018, v. 61, n. 9, p. 623, doi. 10.1111/myc.12773

By:

Hammarström, Helena;
Stjärne Aspelund, Anna;
Christensson, Bertil;
Heußel, Claus Peter;
Isaksson, Jenny;
Kondori, Nahid;
Larsson, Lennart;
Markowicz, Pawel;
Richter, Johan;
Wennerås, Christine;
Friman, Vanda

Publication type:

Article

Androstenediol Reduces Demyelination-Induced Axonopathy in the Rat Corpus Callosum: Impact on Microglial Polarization.

Published in:

Frontiers in Cellular Neuroscience, 2017, v. 11, p. 1, doi. 10.3389/fncel.2017.00049

By:

Kalakh, Samah;
Mouihate, Abdeslam

Publication type:

Article

SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus.

Published in:

PLoS Pathogens, 2016, v. 12, n. 9, p. 1, doi. 10.1371/journal.ppat.1005899

By:

Jöhnk, Bastian;
Bayram, Özgür;
Abelmann, Anja;
Heinekamp, Thorsten;
Mattern, Derek J.;
Brakhage, Axel A.;
Jacobsen, Ilse D.;
Valerius, Oliver;
Braus, Gerhard H.

Publication type:

Article

Clinical validity of bis(methylthio)gliotoxin for the diagnosis of invasive aspergillosis.

Published in:

Applied Microbiology & Biotechnology, 2016, v. 100, n. 5, p. 2327, doi. 10.1007/s00253-015-7209-6

By:

Vidal-García, Matxalen;
Domingo, M.;
De Rueda, Beatriz;
Roc, Lourdes;
Delgado, M.;
Revillo, M.;
Pardo, Julián;
Gálvez, Eva;
Rezusta, Antonio

Publication type:

Article

Heterogeneity in Pathogenicity-related Properties and Stress Tolerance in Aspergillus fumigatus Clinical Isolates.

Published in:

Medical Mycology Journal, 2018, v. 59, n. 4, p. E63, doi. 10.3314/mmj.18-00007

By:

Daisuke Hagiwara;
Hiroki Takahashi;
Hiroshi Takagi;
Akira Watanabe;
Katsuhiko Kamei

Publication type:

Article

Combined Cytotoxicity of the Phycotoxin Okadaic Acid and Mycotoxins on Intestinal and Neuroblastoma Human Cell Models.

Published in:

Toxins, 2018, v. 10, n. 12, p. 526, doi. 10.3390/toxins10120526

By:

Hayashi, Aiko;
José Dorantes-Aranda, Juan;
Bowman, John P.;
Hallegraeff, Gustaaf

Publication type:

Article

Impact of Mycotoxins Secreted by Aspergillus Molds on the Inflammatory Response of Human Corneal Epithelial Cells.

Published in:

Toxins, 2017, v. 9, n. 7, p. 197, doi. 10.3390/toxins9070197

By:

Bossou, Yélian Marc;
Serssar, Youssra;
Allou, Amel;
Vitry, Sandrine;
Momas, Isabelle;
Seta, Nathalie;
Menotti, Jean;
Achard, Sophie

Publication type:

Article

Presence of Multiple Mycotoxins and Other Fungal Metabolites in Native Grasses from a Wetland Ecosystem in Argentina Intended for Grazing Cattle.

Published in:

Toxins, 2015, v. 7, n. 8, p. 3309, doi. 10.3390/toxins7083309

By:

Nichea, María J.;
Palacios, Sofia A.;
Chiacchiera, Stella M.;
Sulyok, Michael;
Krska, Rudolf;
Chulze, Sofia N.;
Torres, Adriana M.;
Ramirez, María L.

Publication type:

Article

Gliotoxin: Nature's Way of Making the Epidithio Bridge.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 13, p. 3312, doi. 10.1002/anie.201310982

By:

Amatov, Tynchtyk;
Jahn, Ullrich

Publication type:

Article

Epidithiodiketopiperazine Biosynthesis: A Four-Enzyme Cascade Converts Glutathione Conjugates into Transannular Disulfide Bridges.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 42, p. 11092, doi. 10.1002/anie.201305059

By:

Scharf, Daniel H.;
Chankhamjon, Pranatchareeya;
Scherlach, Kirstin;
Heinekamp, Thorsten;
Willing, Karsten;
Brakhage, Axel A.;
Hertweck, Christian

Publication type:

Article

Comparison of toxicogenic and immunosuppressive capacity of Aspergillus fumigatus strains isolated from clinical and corn silage samples.

Published in:

Journal of Applied Microbiology, 2015, v. 118, n. 1, p. 175, doi. 10.1111/jam.12673

By:

Dogi, C.;
Alonso, V.;
Fochesato, A.;
Poloni, V.;
Cavaglieri, L.

Publication type:

Article

Gliotoxin contamination in and pre- and postfermented corn, sorghum and wet brewer's grains silage in Sao Paulo and Rio de Janeiro State, Brazil.

Published in:

Journal of Applied Microbiology, 2012, v. 112, n. 5, p. 865, doi. 10.1111/j.1365-2672.2012.05273.x

By:

Keller, L.A.M.;
Keller, K.M.;
Monge, M.P.;
Pereyra, C.M.;
Alonso, V.A.;
Cavaglieri, L.R.;
Chiacchiera, S.M.;
R Rosa, C.A.

Publication type:

Article

Gliotoxin-induced changes in rat liver regeneration after partial hepatectomy.

Published in:

Liver International, 2013, v. 33, n. 7, p. 1044, doi. 10.1111/liv.12164

By:

Nejak‐Bowen, Kari N.;
Orr, Anne V.;
Bowen Jr, William C.;
Michalopoulos, George K.

Publication type:

Article

MRI-guided intracerebral convection-enhanced injection of gliotoxins to induce focal demyelination in swine.

Published in:

PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0204650

By:

Kalkowski, Lukasz;
Malysz-Cymborska, Izabela;
Golubczyk, Dominika;
Janowski, Miroslaw;
Holak, Piotr;
Milewska, Kamila;
Kedziorek, Dorota;
Adamiak, Zbigniew;
Maksymowicz, Wojciech;
Walczak, Piotr

Publication type:

Article

A call to arms: Mustering secondary metabolites for success and survival of an opportunistic pathogen.

Published in:

PLoS Pathogens, 2019, v. 15, n. 4, p. 1, doi. 10.1371/journal.ppat.1007606

By:

Raffa, Nicholas;
Keller, Nancy P.

Publication type:

Article

STUDIES ON THE MUTATION EFFECTS OF GLIOTOXIN DERIVES FROM ASPERGILLUS FUMIGATUS.

Published in:

Biochemical & Cellular Archives, 2021, v. 21, n. 2, p. 5229

By:

Hadi, Yasameen Ali;
Dheeb, Batol Imran;
Al-Hadeithi, Zeina S. M.;
Ibraheem, Anas Noori;
Hadi, Sabreen Ali

Publication type:

Article

Ecophysiology of environmental Aspergillus fumigatus and comparison with clinical strains on gliotoxin production and elastase activity.

Published in:

Letters in Applied Microbiology, 2016, v. 62, n. 2, p. 160, doi. 10.1111/lam.12523

By:

Alonso, V.;
Aminahuel, C.;
Díaz Vergara, L.;
Pereyra, C.;
Poloni, V.;
Dalcero, A.;
Cavaglieri, L.

Publication type:

Article

Typing clinical and animal environment Aspergillus fumigatus gliotoxin producer strains isolated from Brazil by PCR- RFLP markers.

Published in:

Letters in Applied Microbiology, 2013, v. 57, n. 6, p. 484, doi. 10.1111/lam.12136

By:

Soleiro, C.A.;
Pena, G.A.;
Cavaglieri, L.R.;
Coelho, I.;
Keller, L.M.;
Dalcero, A.M.;
Rosa, C.A.R.

Publication type:

Article

Effects of the Combination of Gliotoxin and Adriamycin on the Adriamycin-Resistant Non-Small-Cell Lung Cancer A549 Cell Line.

Published in:

Marine Drugs, 2018, v. 16, n. 4, p. 105, doi. 10.3390/md16040105

By:

Manh Hung, Le Van;
Song, Yeon Woo;
Cho, Somi Kim

Publication type:

Article

Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells.

Published in:

Marine Drugs, 2015, v. 13, n. 10, p. 6259, doi. 10.3390/md13106259

By:

Junxiong Chen;
Chenliang Wang;
Wenjian Lan;
Chunying Huang;
Mengmeng Lin;
Zhongyang Wang;
Wanling Liang;
Aikichi Iwamoto;
Xiangling Yang;
Huanliang Liu

Publication type:

Article

Epipolythiodiketopiperazines from the Marine Derived Fungus Dichotomomyces cejpii with NF-?B Inhibitory Potential.

Published in:

Marine Drugs, 2015, v. 13, n. 8, p. 4949, doi. 10.3390/md13084949

By:

Harms, Henrik;
Orlikova, Barbora;
Ji, Seungwon;
Nesaei-Mosaferan, Damun;
König, Gabriele M.;
Diederich, Marc

Publication type:

Article

Exploring the Chemodiversity and Biological Activities of the Secondary Metabolites from the Marine Fungus Neosartorya pseudofischeri.

Published in:

Marine Drugs, 2014, v. 12, n. 11, p. 5657, doi. 10.3390/md12115657

By:

Wan-Ling Liang;
Xiu Le;
Hou-Jin Li;
Xiang-Ling Yang;
Jun-Xiong Chen;
Jun Xu;
Huan-Liang Liu;
Lai-You Wang;
Kun-Teng Wang;
Kun-Chao Hu;
De-Po Yang;
Wen-Jian Lan

Publication type:

Article

Gliotoxin Isolated from Marine Fungus Aspergillus sp. Induces Apoptosis of Human Cervical Cancer and Chondrosarcoma Cells.

Published in:

Marine Drugs, 2014, v. 12, n. 1, p. 69, doi. 10.3390/md12010069

By:

Nguyen, Van-Tinh;
Jung Suck Lee;
Qian, Zhong-Ji;
Li, Yong-Xin;
Kim, Kil-Nam;
Heo, Soo-Jin;
Jeon, You-Jin;
Won Sun Park;
Choi, Il-Whan;
Je, Jae-Young;
Jung, Won-Kyo

Publication type:

Article

The fungal metabolite gliotoxin inhibits proteasome proteolytic activity and induces an irreversible pseudocystic transformation and cell death in Tritrichomonas foetus.

Published in:

Parasitology Research, 2016, v. 115, n. 8, p. 3057, doi. 10.1007/s00436-016-5061-y

By:

Pereira-Neves, Antonio;
Menna-Barreto, Rubem;
Benchimol, Marlene

Publication type:

Article

Sequencing of Gliotoxin Genes in Clinical and Environmental Aspergillus fumigatus isolates in Iraq.

Published in:

Jornal of Biotechnology Research Center, 2018, v. 12, n. 1, p. 33, doi. 10.24126/jobrc.2018.12.1.546

By:

abdulhadi, Russel S.;
Abdulbaqi, Nemat J.

Publication type:

Article

Production, stability and degradation of Trichoderma gliotoxin in growth medium, irrigation water and agricultural soil.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95907-6

By:

Jayalakshmi, R.;
Oviya, R.;
Premalatha, K.;
Mehetre, S. T.;
Paramasivam, M.;
Kannan, R.;
Theradimani, M.;
Pallavi, M. S.;
Mukherjee, Prasun K.;
Ramamoorthy, V.

Publication type:

Article

Endogenous cross-talk of fungal metabolites.

Published in:

Frontiers in Microbiology, 2015, v. 5, p. 1, doi. 10.3389/fmicb.2014.00732

By:

Sheridan, Kevin J.;
Dolan, Stephen K.;
Doyle, Sean

Publication type:

Article

Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus.

Published in:

G3: Genes | Genomes | Genetics, 2015, v. 5, n. 7, p. 1525, doi. 10.1534/g3.115.016766

By:

Winkelströter, Lizziane K.;
Dolan, Stephen K.;
dos Reis, Thaila Fernanda;
Pedro Bom, Vinícius Leite;
Alves de Castro, Patrícia;
Daisuke Hagiwara;
Alowni, Raneem;
Jones, Gary W.;
Doyle, Sean;
Brown, Neil Andrew;
Goldman, Gustavo H.

Publication type:

Article

Intracellular Delivery of Biologically-Active Fungal Metabolite Gliotoxin Using Magnetic Nanoparticles.

Published in:

Materials (1996-1944), 2019, v. 12, n. 7, p. 1092, doi. 10.3390/ma12071092

By:

Comas, Laura;
Polo, Esther;
Domingo, M Pilar;
Hernández, Yulán;
Arias, Maykel;
Esteban, Patricia;
Martínez-Lostao, Luis;
Pardo, Julián;
Martínez de la Fuente, Jesús;
Gálvez, Eva M

Publication type:

Article

A Unified Strategy to 6-5-6-5-6-Membered Epipolythiodiketopiperazines: Studies towards the Total Synthesis of Scabrosin Diacetate and Haematocin.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 35, p. 12475, doi. 10.1002/chem.201500918

By:

Zipfel, Hannes F.;
Carreira, Erick M.

Publication type:

Article

Combination Treatment Using Pyruvate Kinase M2 Inhibitors for the Sensitization of High Density Triple-negative Breast Cancer Cells.

Published in:

In Vivo, 2022, v. 36, n. 5, p. 2105, doi. 10.21873/invivo.12936

By:

JI SUN LEE;
YUNMOON OH;
JIN-SOL LEE;
JAE HYEON PARK;
JOO-KYUNG SHIN;
JOO-HEE HAN;
HYUNG SIK KIM;
SUNGPIL YOON

Publication type:

Article

Induction of Gliotoxin Secretion in Aspergillus fumigatus by Bacteria-Associated Molecules.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093685

By:

Svahn, K. Stefan;
Göransson, Ulf;
Chryssanthou, Erja;
Olsen, Björn;
Sjölin, Jan;
Strömstedt, Adam A.

Publication type:

Article

The Fumagillin Gene Cluster, an Example of Hundreds of Genes under veA Control in Aspergillus fumigatus.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077147

By:

Dhingra, Sourabh;
Lind, Abigail L.;
Lin, Hsiao-Ching;
Tang, Yi;
Rokas, Antonis;
Calvo, Ana M.

Publication type:

Article

RsmA Regulates Aspergillus fumigatus Gliotoxin Cluster Metabolites Including Cyclo(L-Phe-L-Ser), a Potential New Diagnostic Marker for Invasive Aspergillosis

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062591

By:

Sekonyela, Relebohile;
Palmer, Jonathan M.;
Bok, Jin-Woo;
Jain, Sachin;
Berthier, Erwin;
Forseth, Ry;
Schroeder, Frank;
Keller, Nancy P.

Publication type:

Article

Antifungal Activity of Microbial Secondary Metabolites.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025321

By:

Coleman, Jeffrey J.;
Ghosh, Suman;
Okoli, Ikechukwu;
Mylonakis, Eleftherios

Publication type:

Article

A Novel C2H2 Transcription Factor that Regulates gliA Expression Interdependently with GliZ in Aspergillus fumigatus.

Published in:

PLoS Genetics, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.pgen.1004336

By:

Schoberle, Taylor J.;
Nguyen-Coleman, C. Kim;
Herold, Jennifer;
Yang, Ally;
Weirauch, Matt;
Hughes, Timothy R.;
McMurray, John S.;
May, Gregory S.

Publication type:

Article

Gliotoxin-Producing Endophytic Acremonium sp. from Zingiber officinale Found Antagonistic to Soft Rot Pathogen Pythium myriotylum.

Published in:

Applied Biochemistry & Biotechnology, 2015, v. 175, n. 7, p. 3458, doi. 10.1007/s12010-015-1517-2

By:

Anisha, C.;
Radhakrishnan, E.

Publication type:

Article

Gliotoxin potentiates osteoblast differentiation by inhibiting nuclear factor-κB signaling.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 1, p. 877, doi. 10.3892/mmr.2015.3524

By:

GUANGYE WANG;
XIAOHAI ZHANG;
BAOQING YU;
KE REN

Publication type:

Article

A Peptide of CD14 Protects Human Lymphocytes from Gliotoxin-Induced Apoptosis.

Published in:

International Journal of Peptide Research & Therapeutics, 2012, v. 18, n. 3, p. 249, doi. 10.1007/s10989-012-9298-8

By:

Tartakovsky, Boris;
Sredni, Benjamin;
Zigman-Hoffman, Eti;
Senyor, Gali;
Naparstek, Elizabeth

Publication type:

Article

Novel cutting-edge metabolite-based diagnostic tools for aspergillosis.

Published in:

PLoS Pathogens, 2017, v. 13, n. 9, p. 1, doi. 10.1371/journal.ppat.1006486

By:

Savelieff, Masha G.;
Pappalardo, Lucia

Publication type:

Article

In vitro activity of chlorogenic acid against Aspergillus fumigatus biofilm and gliotoxin production.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 13, n. 6, p. 2637, doi. 10.3892/etm.2017.4317

By:

JIN-LIANG KONG;
JING LUO;
BING LI;
BI-YING DONG;
HONG HUANG;
KE WANG;
LI-HONG WU;
YI-QIANG CHEN

Publication type:

Article

A Bim-activating mould.

Published in:

Cell Death & Differentiation, 2013, v. 20, n. 10, p. 1289, doi. 10.1038/cdd.2013.98

By:

Häcker, G

Publication type:

Article

Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK.

Published in:

Cell Death & Differentiation, 2013, v. 20, n. 10, p. 1317, doi. 10.1038/cdd.2013.78

By:

Geissler, A;
Haun, F;
Frank, D O;
Wieland, K;
Simon, M M;
Idzko, M;
Davis, R J;
Maurer, U;
Borner, C

Publication type:

Article