Works matching DE "GERANYLGERANYLTRANSFERASES"

Results: 54

Drosophila Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11.

Published in:

PLoS Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1371/journal.pbio.1001777

By:

Charng, Wu-Lin;
Yamamoto, Shinya;
Jaiswal, Manish;
Bayat, Vafa;
Xiong, Bo;
Zhang, Ke;
Sandoval, Hector;
David, Gabriela;
Gibbs, Stephen;
Lu, Hsiang-Chih;
Chen, Kuchuan;
Giagtzoglou, Nikos;
Bellen, Hugo J.

Publication type:

Article

Synthesis of geranyl cinnamate by lipase-catalyzed reaction and its evaluation as an antimicrobial agent.

Published in:

Journal of Chemical Technology & Biotechnology, 2017, v. 92, n. 1, p. 115, doi. 10.1002/jctb.4998

By:

Zanetti, Micheli;
Carniel, Thaís Karoline;
Valério, Alexsandra;
Oliveira, J Vladimir de;
Oliveira, Débora de;
Araújo, Pedro HH de;
Riella, Humberto Gracher;
Fiori, Marcio Antônio

Publication type:

Article

A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton.

Published in:

Small GTPases, 2015, v. 6, n. 4, p. 202, doi. 10.1080/21541248.2015.1085485

By:

Ali, Naveid;
Jurczyluk, Julie;
Shay, Gemma;
Tnimov, Zakir;
Alexandrov, Kirill;
Munoz, Marcia A;
Skinner, Oliver P;
Pavlos, Nathan J;
Rogers, Michael J

Publication type:

Article

Production of β-ionone by combined expression of carotenogenic and plant CCD1 genes in Saccharomyces cerevisiae.

Published in:

Microbial Cell Factories, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12934-015-0273-x

By:

López, Javiera;
Essus, Karen;
Il-kwon Kim;
Pereira, Rui;
Herzog, Jan;
Siewers, Verena;
Nielsen, Jens;
Agosin, Eduardo

Publication type:

Article

Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 3, p. 365, doi. 10.1007/s11060-013-1081-y

By:

Zhou, Xiuping;
Liu, Zhi;
Shi, Qiong;
Jiao, Jiantong;
Bian, Wenbin;
Song, Xu;
Mo, Jianbing;
sang, Ben;
Xu, Yinfu;
Qian, Jinming;
Chao, Yuewen;
Yu, Rutong

Publication type:

Article

Molecular cloning and functional characterization of multiple geranylgeranyl pyrophosphate synthases (ApGGPPS) from Andrographis paniculata.

Published in:

Plant Cell Reports, 2019, v. 38, n. 1, p. 117, doi. 10.1007/s00299-018-2353-y

By:

Wang, Jian;
Lin, Hui-Xin;
Su, Ping;
Chen, Tong;
Guo, Juan;
Gao, Wei;
Huang, Lu-Qi

Publication type:

Article

Identification of geranylgeranyl diphosphate synthase genes from Tripterygium wilfordii.

Published in:

Plant Cell Reports, 2015, v. 34, n. 12, p. 2179, doi. 10.1007/s00299-015-1860-3

By:

Zhang, Meng;
Su, Ping;
Zhou, Yong-Jin;
Wang, Xiu-Juan;
Zhao, Yu-Jun;
Liu, Yu-Jia;
Tong, Yu-Ru;
Hu, Tian-Yuan;
Huang, Lu-Qi;
Gao, Wei

Publication type:

Article

Recent Advances in the Development of Mammalian Geranylgeranyl Diphosphate Synthase Inhibitors.

Published in:

Molecules, 2017, v. 22, n. 6, p. 886, doi. 10.3390/molecules22060886

By:

Haney, Staci L.;
Wills, Veronica S.;
Wiemer, David F.;
Holstein, Sarah A.

Publication type:

Article

Synthesis of Linear Geranylphenols and Their Effect on Mycelial Growth of Plant Pathogen Botrytis cinerea.

Published in:

Molecules, 2014, v. 19, n. 2, p. 1512, doi. 10.3390/molecules19021512

By:

Espinoza, Luis;
Taborga, Lautaro;
Díaz, Katy;
Olea, Andrés F.;
Peña-Cortés, Hugo

Publication type:

Article

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures.

Published in:

Molecules, 2013, v. 18, n. 7, p. 7473, doi. 10.3390/molecules18077473

By:

Qiqing Cheng;
Yunfei He;
Geng Li;
Yujia Liu;
Wei Gao;
Luqi Huang

Publication type:

Article

Synthesis of structural analogues of GGT1-DU40, a potent GGTase-1 inhibitor.

Published in:

Zeitschrift für Naturforschung B: A Journal of Chemical Sciences, 2016, v. 71, n. 4, p. 333, doi. 10.1515/znb-2016-0019

By:

Mansha, Muhammad;
Ullah, Nisar;
Alhooshani, Khalid

Publication type:

Article

Improved cis-Abienol production through increasing precursor supply in Escherichia coli.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73934-z

By:

Cheng, Tao;
Zhao, Guang;
Xian, Mo;
Xie, Congxia

Publication type:

Article

Comparative transcriptome analysis of a taxol-producing endophytic fungus, Aspergillus aculeatinus Tax-6, and its mutant strain.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67614-1

By:

Qiao, Weichuan;
Tang, Tianhao;
Ling, Fei

Publication type:

Article

Sulindac inhibits pancreatic carcinogenesis in LSL-KrasG12D-LSL-Trp53R172H-Pdx-1-Cre mice via suppressing aldo-keto reductase family 1B10 (AKR1B10).

Published in:

Carcinogenesis, 2013, v. 34, n. 9, p. 2090, doi. 10.1093/carcin/bgt170

By:

Li, Haonan;
Yang, Allison L.;
Chung, Yeon Tae;
Zhang, Wanying;
Liao, Jie;
Yang, Guang-Yu

Publication type:

Article

Evolutionary comparison of prenylation pathway in kinetoplastid Leishmania and its sister Leptomonas.

Published in:

BMC Evolutionary Biology, 2015, v. 15, p. 1, doi. 10.1186/s12862-015-0538-3

By:

Chauhan, Indira Singh;
Kaur, Jaspreet;
Krishna, Shagun;
Ghosh, Arpita;
Singh, Prashant;
Siddiqi, Mohammad Imran;
Singh, Neeloo

Publication type:

Article

Structural characterization of geranylgeranyl pyrophosphate synthase GACE1337 from the hyperthermophilic archaeon Geoglobus acetivorans.

Published in:

Extremophiles, 2018, v. 22, n. 6, p. 877, doi. 10.1007/s00792-018-1044-5

By:

Petrova, Tatiana E.;
Boyko, Konstantin M.;
Nikolaeva, Alena Yu.;
Stekhanova, Tatiana N.;
Gruzdev, Eugeny V.;
Mardanov, Andrey V.;
Stroilov, Viktor S.;
Littlechild, Jennifer A.;
Popov, Vladimir O.;
Bezsudnova, Ekaterina Yu.

Publication type:

Article

Uremic Toxins Enhance Statin-Induced Cytotoxicity in Differentiated Human Rhabdomyosarcoma Cells.

Published in:

Toxins, 2014, v. 6, n. 9, p. 2612, doi. 10.3390/toxins6092612

By:

Uchiyama, Hitoshi;
Tsujimoto, Masayuki;
Shinmoto, Tadakazu;
Ogino, Hitomi;
Oda, Tomoko;
Yoshida, Takuya;
Furukubo, Taku;
Izumi, Satoshi;
Yamakawa, Tomoyuki;
Tachiki, Hidehisa;
Minegaki, Tetsuya;
Nishiguchi, Kohshi

Publication type:

Article

A Comprehensive Analysis of Choroideremia: From Genetic Characterization to Clinical Practice.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0151943

By:

Sanchez-Alcudia, Rocio;
Garcia-Hoyos, Maria;
Lopez-Martinez, Miguel Angel;
Sanchez-Bolivar, Noelia;
Zurita, Olga;
Gimenez, Ascension;
Villaverde, Cristina;
Rodrigues-Jacy da Silva, Luciana;
Corton, Marta;
Perez-Carro, Raquel;
Torriano, Simona;
Kalatzis, Vasiliki;
Rivolta, Carlo;
Avila-Fernandez, Almudena;
Lorda, Isabel;
Trujillo-Tiebas, Maria J.;
Garcia-Sandoval, Blanca;
Lopez-Molina, Maria Isabel;
Blanco-Kelly, Fiona;
Riveiro-Alvarez, Rosa

Publication type:

Article

Characterization and subcellular localization of geranylgeranyl diphosphate synthase from Catharanthus roseus.

Published in:

Molecular Biology Reports, 2012, v. 39, n. 3, p. 3235, doi. 10.1007/s11033-011-1091-9

By:

Thabet, Insaf;
Guirimand, Grégory;
Guihur, Anthony;
Lanoue, Arnaud;
Courdavault, Vincent;
Papon, Nicolas;
Bouzid, Sadok;
Giglioli-Guivarc'h, Nathalie;
Simkin, Andrew;
Clastre, Marc

Publication type:

Article

Metabolic Stress Induces Caspase-3 Mediated Degradation and Inactivation of Farnesyl and Geranylgeranyl Transferase Activities in Pancreatic β-Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 39, n. 6, p. 2110, doi. 10.1159/000447907

By:

Veluthakal, Rajakrishnan;
arora, Daleep K.;
Goalstone, Marc L.;
Kowluru, Renu a.;
Kowluru, anjaneyulu

Publication type:

Article

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11606-x

By:

Akula, Murali K.;
Ibrahim, Mohamed X.;
Ivarsson, Emil G.;
Khan, Omar M.;
Kumar, Israiel T.;
Erlandsson, Malin;
Karlsson, Christin;
Xu, Xiufeng;
Brisslert, Mikael;
Brakebusch, Cord;
Wang, Donghai;
Bokarewa, Maria;
Sayin, Volkan I.;
Bergo, Martin O.

Publication type:

Article

Novel functions for Rab GTPases in multiple aspects of tumour progression.

Published in:

Biochemical Society Transactions, 2012, v. 40, n. 6, p. 1398, doi. 10.1042/BST20120199

By:

Recchi, Chiara;
Seabra, Miguel C.

Publication type:

Article

GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary.

Published in:

PLoS Genetics, 2017, v. 13, n. 1, p. 1, doi. 10.1371/journal.pgen.1006535

By:

Jiang, Chen;
Diao, Fan;
Sang, Yong-Juan;
Xu, Na;
Zhu, Rui-Lou;
Wang, Xiu-Xing;
Chen, Zhong;
Tao, Wei-Wei;
Yao, Bing;
Sun, Hai-Xiang;
Huang, Xing-Xu;
Xue, Bin;
Li, Chao-Jun

Publication type:

Article

Identification and characterization of the geranylgeranyl diphosphate synthase in Deinococcus radiodurans.

Published in:

Letters in Applied Microbiology, 2014, v. 58, n. 3, p. 219, doi. 10.1111/lam.12181

By:

Liu, C.;
Sun, Z.;
Shen, S.;
Lin, L.;
Li, T.;
Tian, B.;
Hua, Y.

Publication type:

Article

Formation of (R)-2, 3-Dihydrogeranylgeranoic Acid from Geranylgeraniol in Rat Thymocytes1.

Published in:

Journal of Biochemistry, 2002, v. 132, n. 2, p. 327, doi. 10.1093/oxfordjournals.jbchem.a003227

By:

Kodaira, Yuichi;
Usui, Kiyotaka;
Kon, Itaru;
Sagami, Hiroshi

Publication type:

Article

Effects of Random Mutagenesis in a Putative Substrate-Binding Domain of Geranylgeranyl Diphosphate Synthase upon Intermediate Formation and Substrate Specificity1.

Published in:

Journal of Biochemistry, 1997, v. 121, n. 4, p. 696, doi. 10.1093/oxfordjournals.jbchem.a021642

By:

Ohnuma, Shin-ichi;
Hemmi, Hisashi;
Ohto, Chikara;
Nakane, Hiroyuki;
Nishino, Tokuzo

Publication type:

Article

In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells.

Published in:

BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-198

By:

Tripathi, Veenu;
Kwon, Ohyun;
Popescu, Nicholas C.;
Chan, Lai N.;
Zimonjic, Drazen B.;
Lowy, Douglas R.;
Jie Lu;
Tamanoi, Fuyuhiko

Publication type:

Article

Complexes of 1-[3-geranyl-2,4,6-trihydroxyphenyl]-2-methylpropan-1-one with a Cu2+ ion: a DFT study.

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2019, v. 138, n. 1, p. 1, doi. 10.1007/s00214-018-2381-2

By:

Mammino, Liliana

Publication type:

Article

Synergistic Effect of Geranylgeranyltransferase Inhibitor, GGTI, and Docetaxel on the Growth of Prostate Cancer Cells.

Published in:

Prostate Cancer (20903111), 2012, p. 1, doi. 10.1155/2012/989214

By:

Han, Bin;
Fujimoto, Naohiro;
Kobayashi, Mizuki;
Matsumoto, Tetsuro

Publication type:

Article

Effects of geranylgeranylacetone upon cardiovascular diseases.

Published in:

Cardiovascular Therapeutics, 2018, v. 36, n. 4, p. 1, doi. 10.1111/1755-5922.12331

By:

Zeng, Shengqiang;
Wang, Hong;
Chen, Zaihua;
Cao, Qianqiang;
Hu, Lin;
Wu, Yanqing

Publication type:

Article

Inhibiting HDAC1 Enhances the Anti-Cancer Effects of Statins through Downregulation of GGTase-Iβ Expression.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 5, p. 1010, doi. 10.3390/ijms18051010

By:

Ran Li;
Ye-Hua Gan

Publication type:

Article

Inhibitory effects of simvastatin on migration and invasion of rheumatoid fibroblast-like synoviocytes by preventing geranylgeranylation of RhoA.

Published in:

Rheumatology International, 2013, v. 33, n. 2, p. 389, doi. 10.1007/s00296-012-2383-7

By:

Xiao, Youjun;
Liang, Liuqin;
Pan, Yunfeng;
Lian, Fan;
Li, Long;
Lin, Haobo;
Fu, Di;
Fan, Jinjin;
Yang, Xiuyan;
Sun, Lin;
Xu, Hanshi

Publication type:

Article

Rab geranylgeranyl transferase β subunit is essential for male fertility and tip growth in Arabidopsis.

Published in:

Journal of Experimental Botany, 2015, v. 66, n. 1, p. 213, doi. 10.1093/jxb/eru412

By:

Gutkowska, Malgorzata;
Wnuk, Marta;
Nowakowska, Julita;
Lichocka, Malgorzata;
Stronkowski, Michal M.;
Swiezewska, Ewa

Publication type:

Article

Chlorophyll Synthase under Epigenetic Surveillance Is Critical for Vitamin E Synthesis, and Altered Expression Affects Tocopherol Levels in Arabidopsis.

Published in:

Plant Physiology, 2015, v. 168, n. 4, p. 1503, doi. 10.1104/pp.15.00594

By:

Chunyu Zhang;
Wei Zhang;
Guodong Ren;
Delin Li;
Cahoon, Rebecca E.;
Ming Chen;
Yongming Zhou;
Bin Yu;
Cahoon, Edgar B.

Publication type:

Article

Geranylgeranyl pyrophosphate is crucial for neuronal survival but has no special role in Purkinje cell degeneration in Niemann Pick type C1 disease.

Published in:

Journal of Neurochemistry, 2015, v. 133, n. 1, p. 153, doi. 10.1111/jnc.12959

By:

Marschalek, Nils;
Albert, Frank;
Afshordel, Sarah;
Meske, Volker;
Eckert, Gunter P.;
Ohm, Thomas G.

Publication type:

Article

Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain.

Published in:

Journal of Neurochemistry, 2014, v. 129, n. 4, p. 732, doi. 10.1111/jnc.12654

By:

Afshordel, Sarah;
Wood, Wellington Gibson;
Igbavboa, Urule;
Muller, Walter E.;
Eckert, Gunter P.

Publication type:

Article

Geranylgeranyltransferase I mediates BDNF-induced synaptogenesis.

Published in:

Journal of Neurochemistry, 2013, v. 125, n. 5, p. 698, doi. 10.1111/jnc.12249

By:

Li, Zhengwei;
Sun, Chengdong;
Zhang, Tao;
Mo, Jianbing;
Shi, Qiong;
Zhang, Xianfeng;
Yuan, Maochun;
Chen, Long;
Mao, Xueqiang;
Yu, Rutong;
Zhou, Xiuping

Publication type:

Article

Pericolactines A-C, a New Class of Diterpenoid Alkaloids with Unusual Tetracyclic Skeleton.

Published in:

Scientific Reports, 2015, p. 17082, doi. 10.1038/srep17082

By:

Wu, Yue-Hua;
Chen, Guo-Dong;
He, Rong-Rong;
Wang, Chuan-Xi;
Hu, Dan;
Wang, Gao-Qian;
Guo, Liang-Dong;
Yao, Xin-Sheng;
Gao, Hao

Publication type:

Article

Distinct evolutionary strategies in the GGPPS family from plants.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00230

By:

Coman, Diana;
Altenhoff, Adrian;
Zoller, Stefan;
Gruissem, Wilhelm;
Vranova, Eva

Publication type:

Article

Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137595

By:

Lu, Jie;
Yoshimura, Kohei;
Goto, Koichi;
Lee, Craig;
Hamura, Ken;
Kwon, Ohyun;
Tamanoi, Fuyuhiko

Publication type:

Article

Lil3 Assembles with Proteins Regulating Chlorophyll Synthesis in Barley.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133145

By:

Mork-Jansson, Astrid;
Bue, Ann Kristin;
Gargano, Daniela;
Furnes, Clemens;
Reisinger, Veronika;
Arnold, Janine;
Kmiec, Karol;
Eichacker, Lutz Andreas

Publication type:

Article

Rab GTPase Prenylation Hierarchy and Its Potential Role in Choroideremia Disease.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0081758

By:

Köhnke, Monika;
Delon, Christine;
Hastie, Marcus L.;
Nguyen, Uyen T. T.;
Wu, Yao-Wen;
Waldmann, Herbert;
Goody, Roger S.;
Gorman, Jeffrey J.;
Alexandrov, Kirill

Publication type:

Article

Mutation of the Light-Induced Yellow Leaf 1 Gene, Which Encodes a Geranylgeranyl Reductase, Affects Chlorophyll Biosynthesis and Light Sensitivity in Rice.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075299

By:

Zhou, Yong;
Gong, Zhiyun;
Yang, Zefeng;
Yuan, Yuan;
Zhu, Jinyan;
Wang, Man;
Yuan, Fuhai;
Wu, Shujun;
Wang, Zhiqin;
Yi, Chuandeng;
Xu, Tinghua;
Ryom, MyongChol;
Gu, Minghong;
Liang, Guohua

Publication type:

Article

Effect of lovastatin on small GTP binding proteins and on TGF-β1 and fibronectin expression.

Published in:

Kidney International, 2000, v. 58, p. S88, doi. 10.1046/j.1523-1755.2000.07714.x

By:

Kim, Sung Il;
Kim, Hey Jin;
Han, Dong Cheol;
Lee, Hi Bahl

Publication type:

Article

Importance of geranylgeranyl pyrophosphate for mesangial cell DNA synthesis.

Published in:

Kidney International, 1999, v. 56, p. S80, doi. 10.1038/sj.ki.4495407

By:

Massy, Ziad A.;
Guijarro, Carlos;
Oda, Hiroaki;
Kasiske, Bertram L.;
Keane, William F.;
O'Donnell, Michael P.

Publication type:

Article

Extending our tools and resources in the non-conventional industrial yeast <italic>Xanthophyllomyces dendrorhous</italic> through the application of metabolite profiling methodologies.

Published in:

Metabolomics, 2018, v. 14, n. 3, p. 0, doi. 10.1007/s11306-017-1313-9

By:

Alcalde, Eugenio;
Fraser, Paul D.

Publication type:

Article

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.

Published in:

eLife, 2015, p. 1, doi. 10.7554/eLife.05560

By:

Schumacher, Marc M.;
Elsabrouty, Rania;
Youngah Jo;
Seemann, Joachim;
DeBose-Boyd, Russell A.

Publication type:

Article

Isoprenoid biosynthesis in the diatom Haslea ostrearia.

Published in:

New Phytologist, 2019, v. 222, n. 1, p. 230, doi. 10.1111/nph.15586

By:

Athanasakoglou, Anastasia;
Grypioti, Emilia;
Michailidou, Sofia;
Ignea, Codruta;
Makris, Antonios M.;
Kalantidis, Kriton;
Massé, Guillaume;
Argiriou, Anagnostis;
Verret, Frederic;
Kampranis, Sotirios C.

Publication type:

Article

A Possible Trifunctional β-Carotene Synthase Gene Identified in the Draft Genome of Aurantiochytrium sp. Strain KH105.

Published in:

Genes, 2018, v. 9, n. 4, p. 200, doi. 10.3390/genes9040200

By:

Iwasaka, Hiroaki;
Koyanagi, Ryo;
Satoh, Ryota;
Nagano, Akiko;
Watanabe, Kenshi;
Hisata, Kanako;
Satoh, Noriyuki;
Aki, Tsunehiro

Publication type:

Article

Geranylgeranyl transferase 1 inhibitor GGTI-298 enhances the anticancer effect of gefitinib.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 4, p. 4023, doi. 10.3892/mmr.2018.9371

By:

Liu, Bi-Sheng;
Dai, Xin-Yu;
Xia, Hong-Wei;
Xu, Huan-Ji;
Tang, Qiu-Lin;
Gong, Qi-Yong;
Nie, Yong-Zhan;
Bi, Feng

Publication type:

Article