Works about GENOME-wide association studies

Results: 5000

Mendelian randomization analysis reveals the potential of the IKZF1 gene as a therapeutic target in colorectal cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02683-0

By:

Lin, Junzuo;
Xu, Qian;
Zhao, Zhengfei

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Article

Meis transcription factors regulate cardiac conduction system development and adult function Open Access.

Published in:

Cardiovascular Research, 2025, v. 121, n. 2, p. 311, doi. 10.1093/cvr/cvae258

By:

Muñoz-Martín, Noelia;
Simon-Chica, Ana;
Díaz-Díaz, Covadonga;
Cadenas, Vanessa;
Temiño, Susana;
Esteban, Isaac;
Ludwig, Andreas;
Schormair, Barbara;
Winkelmann, Juliane;
Olejnickova, Veronika;
Sedmera, David;
Filgueiras-Rama, David;
Torres, Miguel

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Article

Causal Effect of Residual Cholesterol on Psoriatic Arthritis: a Mendelian Randomization Study.

Published in:

Clinical Laboratory, 2025, v. 71, n. 5, p. 892, doi. 10.7754/Clin.Lab.2025.250118

By:

Wenying Long;
Quan Miao

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Article

The Genetics of Plant–Plant Interactions and Their Cascading Effects on Agroecosystems—from Model Plants to Applications Open Access.

Published in:

Plant & Cell Physiology, 2025, v. 66, n. 4, p. 477, doi. 10.1093/pcp/pcae092

By:

Sato, Yasuhiro;
Wuest, Samuel E

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Article

Beyond the Standard GWAS—A Guide for Plant Biologists Open Access.

Published in:

Plant & Cell Physiology, 2025, v. 66, n. 4, p. 431, doi. 10.1093/pcp/pcae079

By:

Clauw, Pieter;
Ellis, Thomas James;
Liu, Hai-Jun;
Sasaki, Eriko

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Article

Population structure, genetic diversity, and GWAS analyses with GBS-derived SNPs and silicodart markers unveil genetic potential for breeding and candidate genes for agronomic and root quality traits in an international sugar beet germplasm collection.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06525-7

By:

Bahjat, Noor Maiwan;
Yıldız, Mehtap;
Nadeem, Muhammad Azhar;
Morales, Andres;
Wohlfeiler, Josefina;
Baloch, Faheem Shahzad;
Tunçtürk, Murat;
Koçak, Metin;
Chung, Yong Suk;
Grzebelus, Dariusz;
Sadik, Gökhan;
Kuzğun, Cansu;
Cavagnaro, Pablo Federico

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Article

Application of multi-omics technology in pathogen identification and resistance gene screening of sheep pneumonia.

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BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11699-3

By:

Huang, Kai;
Yuan, Lvfeng;
Liu, Jia;
Li, Xiaolong;
Xu, Dan;
Zhang, Xiaoxue;
Peng, Jie;
Tian, Huibin;
Li, Fadi;
Wang, Weimin

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Article

Identification of regulatory loci and candidate genes related to body weight traits in broilers based on different models.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11651-5

By:

Luo, Na;
Cai, Keqi;
Wei, Limin;
Cui, Huanxian;
Wen, Jie;
An, Bingxing;
Zhao, Guiping

Publication type:

Article

Mendelian randomization analysis reveals the potential of the IKZF1 gene as a therapeutic target in colorectal cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02683-0

By:

Lin, Junzuo;
Xu, Qian;
Zhao, Zhengfei

Publication type:

Article

The causal association between psoriasis and 32 types of cancer: a mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02679-w

By:

Li, Guangyao;
Tian, Jiahe;
Xu, Jingyu;
Li, Kun

Publication type:

Article

Unraveling the causal pathway between phosphatidylinositol, metabolites, and metabolic syndrome: a Mendelian randomization study.

Published in:

Diabetology & Metabolic Syndrome, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13098-025-01731-7

By:

Yang, YueGuang;
Ma, YanLing;
Li, Ming;
Han, YuBo;
Liu, Li

Publication type:

Article

Integrating exosome wide associations study and Mendelian randomization identified causal miRNAs for type 2 diabetes mellitus and its complications.

Published in:

Diabetology & Metabolic Syndrome, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13098-025-01725-5

By:

Li, Dong-Ling;
Ding, Xin-Yi;
He, Qiao-Ling;
Zhan, Wan-Hua;
Long, Juan;
He, Mei-Nan;
Zhang, Jia-Lu;
Zeng, Qing-Xiang;
Lu, Na;
Chi, Yong-Qian;
Zou, Meng-Chen

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Article

Osteoporosis and stroke: a bidirectional mendelian randomization study.

Published in:

Journal of Bone & Mineral Metabolism, 2025, v. 43, n. 3, p. 256, doi. 10.1007/s00774-025-01579-x

By:

He, Miao;
Yong, Haochuan;
Cao, Zhidong;
Li, Jie

Publication type:

Article

Genetic Investigation of Inherited Variants in a Multiplex Autism Spectrum Disorder (ASD) Family Using Whole-Genome Sequencing (WGS).

Published in:

Iranian Journal of Public Health, 2025, v. 54, n. 5, p. 1087, doi. 10.18502/ijph.v54i5.18643

By:

Gholizadeh, Mehdi Agha;
Behjati, Farkhondeh;
Garshasbi, Masoud

Publication type:

Article

The Causal Relationship Between Serum Metabolites and Allergic Diseases: Mendelian Randomization Analysis.

Published in:

Clinical & Experimental Allergy, 2025, v. 55, n. 5, p. 436, doi. 10.1111/cea.14615

By:

Qiu, Yanli;
Zhang, Bing;
Chen, Haocong;
Zhang, Jialin;
Zhang, Yu;
Zhang, Junfeng;
Lin, Hongxia;
Lu, Yinzhong

Publication type:

Article

Integrative genetic and epigenetic control of skeletal muscle fiber traits in agricultural animals.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1566553

By:

Chang, Xiaolong;
Ma, Junwu

Publication type:

Article

Shared genetic architecture between leukocyte telomere length and Alzheimer's disease.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01757-z

By:

Cao, Zhi;
Tan, Qilong;
Yang, Hongxi;
Xu, Chenjie

Publication type:

Article

Evaluating the causal effects of life-course adiposity on jaw anomalies.

Published in:

Progress in Orthodontics (2196-1042), 2025, v. 26, n. 1, p. 1, doi. 10.1186/s40510-025-00565-3

By:

Chen, Xin;
Cheng, Zheng;
Wang, Qianyi;
Jiang, Yubin;
Cheng, Qing;
Jiang, Qianglin

Publication type:

Article

Genome-wide association analysis in peanut accessions uncovers the genetic basis regulating oil and fatty acid variation.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06690-9

By:

Xu, Jing;
Jiang, Xiao;
Yin, Xiangzhen;
Zhao, Xuhong;
Chen, Na;
Pan, Lijuan;
Fu, Chun;
Jiao, Yanlin;
Ma, Junqing;
Yuan, Mei;
Chi, Xiaoyuan

Publication type:

Article

Genetic dissection of hundred-kernel weight through combined genome-wide association study and linkage analysis in tropical maize.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11682-y

By:

Shi, Mengfei;
Jiang, Fuyan;
Shaw, Ranjan K.;
Ijaz, Babar;
Sun, Jiachen;
Fan, Xingming

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Article

The potential value of genotyping by sequencing (GBS) strategies for combating citrus diseases.

Published in:

Euphytica, 2025, v. 221, n. 5, p. 1, doi. 10.1007/s10681-025-03511-w

By:

Deol, Jaideep Kaur;
Ramekar, Sheetal;
Dutt, Manjul

Publication type:

Article

Identification of candidate genes for improving phosphorus use efficiency in a cowpea (Vigna unguiculata (L.) Walp.) multi-parent advanced generation inter-cross (MAGIC) population.

Published in:

Euphytica, 2025, v. 221, n. 5, p. 1, doi. 10.1007/s10681-025-03510-x

By:

Ohlson, Erik W.;
Zhang, Xiaoxuan;
Hicks, Rebecca K.;
Timko, Michael P.

Publication type:

Article

Genome-wide association study for compactness traits in oil palm (Elaeis guineensis Jacq.).

Published in:

Euphytica, 2025, v. 221, n. 5, p. 1, doi. 10.1007/s10681-025-03502-x

By:

Samsudin, Amer Izzat;
Vetaryan, Sharmilah;
Ahmad Mohktar, Mohd Azinuddin;
Abdul Rahim, Muhamad Farid;
Ting, Ngoot-Chin;
Zolkafli, Siti Hazirah;
Singh, Rajinder;
Ramlee, Shairul Izan;
Lee, Yang Ping

Publication type:

Article

Genome-wide association study and genomic prediction for pod-shattering tolerance in a diverse rapeseed/canola germplasm collection.

Published in:

Euphytica, 2025, v. 221, n. 5, p. 1, doi. 10.1007/s10681-025-03494-8

By:

Hosain, Shakil;
Horvath, David P.;
Roy, Jayanta;
Hoque, Ahasanul;
Arifuzzaman, Muhammad;
Rahman, Mukhlesur

Publication type:

Article

Genome-wide association studies on malaria in Sub-Saharan Africa: A scoping review.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0309268

By:

Akoth, Morine;
Odhiambo, John;
Omolo, Bernard

Publication type:

Article

Identification and genetic analysis of candidate genes for resistance against Phytophthora sojae in soybean using a genome-wide association study.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1520999

By:

Park, Hye Rang;
Heo, Su Vin;
Kang, Beom Kyu;
Seo, Hyoseob;
Lee, Eunsoo;
Park, Jihee;
Jang, Yun Woo;
Seo, Jeong Hyun;
Park, Girim;
Kim, Jun Hoi;
Lee, Yeong Hoon;
Han, Won Young;
Seo, Myung Chul;
Jeung, Ji-Ung

Publication type:

Article

Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1554216

By:

Atsbeha, Genet;
Mekonnen, Tilahun;
Brhane, Haftom;
Kebede, Mulugeta;
Haileselassie, Teklehaimanot;
Tesfaye, Kassahun

Publication type:

Article

Genetically Predicted Immune Cell-Mediated Effect of Lipid Metabolism on Allergic Diseases: A Two-Step, Mediation Mendelian Randomization Study.

Published in:

International Archives of Allergy & Immunology, 2025, v. 186, n. 5, p. 430, doi. 10.1159/000542036

By:

Wang, Yao;
Mou, Ya-Kui;
Liu, Wan-Chen;
Wang, Han-Rui;
Song, Xiao-Yu;
Yang, Ting;
Ren, Chao;
Song, Xi-Cheng

Publication type:

Article

Exploring causal associations between plasma metabolites and attention-deficit/hyperactivity disorder.

Published in:

BMC Psychiatry, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12888-025-06951-9

By:

Shi, Shangyun;
Baranova, Ancha;
Cao, Hongbao;
Zhang, Fuquan

Publication type:

Article

Exploring the causal relationship between immune factors and chondrosarcoma: a Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02654-5

By:

Xu, Taichuan;
Xiao, Wentao;
Li, Wenjie;
Xu, Xianfa;
Zhang, Haiwen;
Zhang, Xian

Publication type:

Article

Integrating single-cell with transcriptome-proteome Mendelian randomization reveals colorectal cancer targets.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02636-7

By:

Wang, Song;
Yao, Xin;
Li, Shenshen;
Wang, Shanshan;
Huang, Xuyu;
Zhou, Jing;
Li, Xiao;
Wen, Jieying;
Lan, Weixuan;
Huang, Yunsi;
Li, Hao;
Sun, Yunlong;
Zhao, Xiaoqian;
Chen, Qiaoling;
Han, Xuedong;
Zhu, Ziming;
Zhang, Xinyue;
Zhang, Tao

Publication type:

Article

Causal relationships between four types of lipids and breast cancer risk with potential mediators: evidence from Mendelian randomization study and bioinformatics analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02597-x

By:

Li, Xu-Chu;
Wang, Bangqi;
Tang, Yu

Publication type:

Article

Association between Apolipoprotein B and diabetic nephropathy: insights from the National Health and Nutrition Examination Survey 2007–2016 and Mendelian randomization analysis.

Published in:

Nutrition & Diabetes, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41387-025-00370-1

By:

Wang, Hui;
Wu, Sensen;
Pan, Dikang;
Ning, Yachan;
Fu, Yanhong;
Feng, Chunjing;
Guo, Jianming;
Liu, Zichuan;
Gu, Yongquan

Publication type:

Article

The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian randomization study.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99742-x

By:

Zheng, Qifan;
Xu, Tong;
Luo, Shiyin;
Zhao, Jiahui;
Ying, Yue;
Liu, Nan;
Jiang, Aijia;
Pan, Yaping;
Zhang, Dongmei

Publication type:

Article

Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-01634-7

By:

Kodate, Shun;
Sato, Mitsuharu;
Hishinuma, Eiji;
Kojima, Kaname;
Motoike, Ikuko N.;
Abe, Hikaru;
Abe, Michiaki;
Abe, Momoka;
Abe, Naomi;
Abe, Noriko;
Abe, Tomomi;
Abe, Yuto;
Ahiko, Shizuko;
Aiki, Kayo;
Aizawa, Hiromi;
Akiyama, Yukari;
Anzawa, Hayato;
Aoki, Eri;
Aoki, Yuichi;
Arai, Hiroko

Publication type:

Article

Rethinking GWAS: how lessons from genetic screens and artificial intelligence could reveal biological mechanisms Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 4, p. 1, doi. 10.1093/bioinformatics/btaf153

By:

Hazelett, Dennis J

Publication type:

Article

Genome-wide enhancer-gene regulatory maps of liver reveal novel regulatory mechanisms underlying NAFLD pathogenesis.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11668-w

By:

Li, Ruofan;
Su, Kaiyan;
Wu, Tianzhun;
Xu, Li;
Song, Wenyu;
Sun, Dandan;
Zeng, Tao;
Chen, Jinzhang;
Xin, Haibei;
Li, Yuanfeng;
Zang, Mengya;
Hu, Minggen

Publication type:

Article

A causal relationship between hypothyroidism and rheumatoid arthritis, but not hyperthyroidism: evidence from the mendelian randomization study.

Published in:

Wiener Klinische Wochenschrift, 2025, v. 137, n. 9, p. 279, doi. 10.1007/s00508-024-02386-6

By:

Yang, Mingyi;
Su, Yani;
Xu, Ke;
Wen, Pengfei;
Guo, Jianbin;
Yang, Zhi;
Liu, Lin;
Xu, Peng

Publication type:

Article

SOX7: Autism associated gene identified by analysis of multi-Omics data.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0320096

By:

Gonzales, Samantha;
Zhao, Jane Zizhen;
Choi, Na Young;
Acharya, Prabha;
Jeong, Sehoon;
Wang, Xuexia;
Lee, Moo-Yeal

Publication type:

Article

Development and validation of a polygenic risk score for height in a Greek cohort: Association with blood pressure measurements.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1538975

By:

Kalafati, Ioanna Panagiota;
Tsifintaris, Margaritis;
Dimitriou, Maria;
Grigoriou, Effimia;
Moulos, Panagiotis;
Dedoussis, George V.

Publication type:

Article

GENOME-WIDE ASSOCIATION STUDY IDENTIFIED QTLS FOR BEHAVIORAL TRAITS IN KOREAN SAPSAREE DOGS.

Published in:

JAPS: Journal of Animal & Plant Sciences, 2025, v. 35, n. 2, p. 546, doi. 10.36899/japs.2025.2.0045

By:

Haque, Md Azizul;
Kim, Na-Kuang;
Yeji, Ryu;
Lee, B.;
Ha, Ji-Hong;
Lee, Yun-Mi;
Il, Han-Kook;
Kim, Jong-Joo

Publication type:

Article

Associations of Genetically Predicted NPR3 and NPR2 Perturbation and Preeclampsia Risk: A Two‐Sample Mendelian Randomization Analysis.

Published in:

International Journal of Hypertension, 2025, v. 2025, p. 1, doi. 10.1155/ijhy/9972031

By:

Harpe, Roxane de La;
Rogne, Tormod;
Nyberg, Michael;
Cronjé, Héléne T.;
Burgess, Stephen;
Karhunen, Ville;
Gill, Dipender;
Pivetta, Emanuele

Publication type:

Article

Genetic architecture of thermotolerance traits in beef cattle: a novel integration of SNP and breed-of-origin effects.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1576966

By:

Zayas, Gabriel A.;
Santos Rojas, Camila;
Rodriguez, Eduardo E.;
Hernandez, Aakilah S.;
Beard, Ashley M.;
Rafiq, Fahad;
Sarlo Davila, Kaitlyn M.;
Mateescu, Raluca G.

Publication type:

Article

A genome-wide investigation of Mycoplasma hominis genes associated with gynecological infections or infertility.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1561378

By:

Chibani, Salim;
Yacoub, Elhem;
Boujemaa, Safa;
Mardassi, Helmi;
Guglielmini, Julien;
Vaysse, Amaury;
Khadraoui, Nadine;
Mlik, Béhija;
Ben Abdelmoumen Mardassi, Boutheina

Publication type:

Article

Role of molecular breeding in understanding salinity tolerance in cotton: limitations and perspectives.

Published in:

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2025, v. 53, n. 1, p. 1, doi. 10.15835/nbha53114297

By:

Shicong WANG;
Meiling HOU;
HASSAN, Hadiqa;
ABBAS, Fatima M.;
AL AHMAD, Zehbah A.;
QARI, Sameer H.;
HANIFAH, Nurul A. B.

Publication type:

Article

Integration of metabolomics and genomics implicates a causality between 1398 blood metabolites and gout.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 5, p. 2053, doi. 10.1007/s10067-025-07402-2

By:

Fan, Mingyuan;
Yun, Zhangjun;
Yuan, Jiushu;
Lu, Dingyi;
Xie, Hongyan;
Yuan, Haipo;
Gao, Hong

Publication type:

Article

Dissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study.

Published in:

Reproductive Biology & Endocrinology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12958-025-01406-y

By:

Shao, Huijing;
Xu, Chang;
Wang, Haoran;
Lu, Nan;
Gu, Hang;
Zhang, Caihong;
Li, Lirong;
Sun, Qianqian;
Guan, Rui;
Xuan, Beibei

Publication type:

Article

Phenotypic plasticity of flowering time and plant height related traits in wheat.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06489-8

By:

Chen, Ying;
Dong, Hai-Bin;
Peng, Chao-Jun;
Du, Xi-Jun;
Li, Chun-Xin;
Han, Xue-Lian;
Sun, Wen-Xian;
Zhang, Yuan-Ming;
Hu, Lin

Publication type:

Article

CD28<sup>+</sup> CD45RA<sup>−</sup> CD8br AC mediated the effects of Interleukin- 6 on Alzheimer's disease: A Mendelian Randomization Study.

Published in:

BMC Neurology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12883-025-04194-5

By:

Xu, Rui;
Gao, YongJun

Publication type:

Article

Uncovering the genomic basis of phenological traits in Chouardia litardierei (Asparagaceae) through a genome-wide association study (GWAS).

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1571608

By:

Šarančić, Sara Laura;
Pleić, Nikolina;
Križanović, Krešimir;
Surina, Boštjan;
Mitić, Damjan;
Radosavljević, Ivan

Publication type:

Article