Works matching DE "GENOME editing"
Results: 5000
CRISPR-aided genome engineering for secondary metabolite biosynthesis in Streptomyces.
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- Journal of Industrial Microbiology & Biotechnology, 2024, v. 51, p. 1, doi. 10.1093/jimb/kuae009
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Expanding the synthetic biology toolbox of Cupriavidus necator for establishing fatty acid production.
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- Journal of Industrial Microbiology & Biotechnology, 2024, v. 51, p. 1, doi. 10.1093/jimb/kuae008
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Piggybacking on nature: exploring the multifaceted world of porcine β-defensins.
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- Veterinary Research, 2025, v. 56, n. 1, p. 1, doi. 10.1186/s13567-025-01465-4
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Full sequencing of 100mer sgRNA via tandem mass spectrometry by targeted RNase H digestion with customized probes.
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- Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 8, p. 1497, doi. 10.1007/s00216-025-05737-y
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AZD7648 (DNA-PKcs inhibitor): a two-edged sword for editing genomes.
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- Functional & Integrative Genomics, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10142-025-01560-x
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Prime Editing: Mechanistic Insights and DNA Repair Modulation.
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- Cells (2073-4409), 2025, v. 14, n. 4, p. 277, doi. 10.3390/cells14040277
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A Novel Quantification Method for Gene-Edited Animal Detection Based on ddPCR.
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- Biology (2079-7737), 2025, v. 14, n. 2, p. 203, doi. 10.3390/biology14020203
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Non-Invasive Delivery of CRISPR/Cas9 Ribonucleoproteins (Cas9 RNPs) into Cells via Nanoparticles for Membrane Transport.
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- Pharmaceutics, 2025, v. 17, n. 2, p. 201, doi. 10.3390/pharmaceutics17020201
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Utilizing Target Sequences with Multiple Flanking Protospacer Adjacent Motif (PAM) Sites Reduces Off-Target Effects of the Cas9 Enzyme in Pineapple.
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- Genes, 2025, v. 16, n. 2, p. 217, doi. 10.3390/genes16020217
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Molecular and Digital Innovation in Pediatric Surgery.
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- Molecular Frontiers Journal, 2024, v. 8, n. 1/2, p. 37, doi. 10.1142/S2529732524500032
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Sickle Cell Anemia and Inflammation: A Review of Stones and Landmarks Paving the Road in the Last 25 Years.
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- Hematology Reports, 2025, v. 17, n. 1, p. 2, doi. 10.3390/hematolrep17010002
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Peanut Genotypes with Reduced Content of Immunogenic Proteins by Breeding, Biotechnology, and Management: Prospects and Challenges.
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- Plants (2223-7747), 2025, v. 14, n. 4, p. 626, doi. 10.3390/plants14040626
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Functional characterization in Chimonobambusa utilis reveals the role of bHLH gene family in bamboo sheath color variation.
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- Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1514703
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- Article
Risk Prediction of RNA Off-Targets of CRISPR Base Editors in Tissue-Specific Transcriptomes Using Language Models.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1723, doi. 10.3390/ijms26041723
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CRISPR/Cas9 Genome Editing in the Diamondback Moth: Current Progress, Challenges, and Prospects.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1515, doi. 10.3390/ijms26041515
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Gene Therapy: An Historical Overview for Familial Hearing Loss.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1469, doi. 10.3390/ijms26041469
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From Origin to the Present: Establishment, Mechanism, Evolutions and Biomedical Applications of the CRISPR/Cas-Based Macromolecular System in Brief.
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- Molecules, 2025, v. 30, n. 4, p. 947, doi. 10.3390/molecules30040947
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CRISPRCas系统在枯草芽孢杆菌基因组编辑中的研究进展.
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- Journal of Agricultural Science & Technology (1008-0864), 2025, v. 27, n. 2, p. 24, doi. 10.13304/j.nykjdb.2023.0260
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Breaking Barriers to an HIV-1 Cure: Innovations in Gene Editing, Immune Modulation, and Reservoir Eradication.
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- Life (2075-1729), 2025, v. 15, n. 2, p. 276, doi. 10.3390/life15020276
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Simplified Protocol for the Purification of Native Cas Nucleases for DNA-Free Genome Editing.
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- Methods & Protocols, 2025, v. 8, n. 1, p. 16, doi. 10.3390/mps8010016
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CRISPR-Based Genetic Improvement of Aquaculture Species.
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- Fishes (MDPI AG), 2025, v. 10, n. 2, p. 84, doi. 10.3390/fishes10020084
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Mutation of Genes Associated with Body Color, Growth, Intermuscular Bone, and Sex Differentiation in Onychostoma macrolepis Using CRISPR/Cas9.
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- Fishes (MDPI AG), 2025, v. 10, n. 2, p. 40, doi. 10.3390/fishes10020040
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An overview of recent US-approved gene therapies for Duchenne muscular dystrophy and their respective clinical development programs.
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- Drugs & Therapy Perspectives, 2023, v. 39, n. 4, p. 156, doi. 10.1007/s40267-023-00986-2
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When size matters: A novel compact Cas12a variant for in vivo genome editing.
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- PLoS Biology, 2024, v. 22, n. 7, p. 1, doi. 10.1371/journal.pbio.3002637
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Engineering of a high-fidelity Cas12a nuclease variant capable of allele-specific editing.
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- PLoS Biology, 2024, v. 22, n. 6, p. 1, doi. 10.1371/journal.pbio.3002680
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Engineering of a compact, high-fidelity EbCas12a variant that can be packaged with its crRNA into an all-in-one AAV vector delivery system.
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- PLoS Biology, 2024, v. 22, n. 5, p. 1, doi. 10.1371/journal.pbio.3002619
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Sensitivity of osteosarcoma cell lines to autophagy inhibition as determined by pharmacologic and genetic manipulation.
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- Veterinary & Comparative Oncology, 2023, v. 21, n. 4, p. 726, doi. 10.1111/vco.12937
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Gene Editing, Identity and Benefit.
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- Philosophical Quarterly, 2022, v. 72, n. 2, p. 305, doi. 10.1093/pq/pqab029
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Solid‐State NMR Exploration of Factors for Enhancement of Hole Mobility by Introduction of Poly(styrene) Into Poly(3‐hexylthiophene).
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- Macromolecular Chemistry & Physics, 2024, v. 225, n. 22, p. 1, doi. 10.1002/macp.202400225
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Harnessing Gene Editing Technology for Tumor Microenvironment Modulation: An Emerging Anticancer Strategy.
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- Chemistry - A European Journal, 2024, v. 30, n. 62, p. 1, doi. 10.1002/chem.202402485
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Universal crRNA Acylation Strategy for Robust Photo‐Initiated One‐Pot CRISPR–Cas12a Nucleic Acid Diagnostics.
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- Angewandte Chemie, 2024, v. 136, n. 23, p. 1, doi. 10.1002/ange.202401486
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- Article
Near‐Infrared Light Activated Formulation for the Spatially Controlled Release of CRISPR‐Cas9 Ribonucleoprotein for Brain Gene Editing.
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- Angewandte Chemie, 2024, v. 136, n. 21, p. 1, doi. 10.1002/ange.202401004
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- Article
PAM‐Engineered Toehold Switches as Input‐Responsive Activators of CRISPR‐Cas12a for Sensing Applications.
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- Angewandte Chemie, 2024, v. 136, n. 17, p. 1, doi. 10.1002/ange.202319677
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Engineering Anti‐CRISPR Proteins to Create CRISPR‐Cas Protein Switches for Activatable Genome Editing and Viral Protease Detection.
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- Angewandte Chemie, 2024, v. 136, n. 16, p. 1, doi. 10.1002/ange.202400599
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Supramolecular Genome Editing: Targeted Delivery and Endogenous Activation of CRISPR/Cas9 by Dynamic Host‐Guest Recognition.
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- Angewandte Chemie, 2024, v. 136, n. 14, p. 1, doi. 10.1002/ange.202316323
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A DNA Origami‐Based Gene Editing System for Efficient Gene Therapy in Vivo.
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- Angewandte Chemie, 2023, v. 135, n. 51, p. 1, doi. 10.1002/ange.202315093
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- Article
A Gene‐Editable Palladium‐Based Bioorthogonal Nanoplatform Facilitates Macrophage Phagocytosis for Tumor Therapy.
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- Angewandte Chemie, 2023, v. 135, n. 50, p. 1, doi. 10.1002/ange.202313968
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- Article
Engineering Nucleotidoproteins for Base‐Pairing‐Assisted Cytosolic Delivery and Genome Editing.
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- Angewandte Chemie, 2023, v. 135, n. 45, p. 1, doi. 10.1002/ange.202307664
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- Article
Bioorthogonal Reaction‐Mediated Tumor‐Selective Delivery of CRISPR/Cas9 System for Dual‐Targeted Cancer Immunotherapy.
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- Angewandte Chemie, 2023, v. 135, n. 37, p. 1, doi. 10.1002/ange.202306863
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- Article
Phosphorothioated DNA Engineered Liposomes as a General Platform for Stimuli‐Responsive Cell‐Specific Intracellular Delivery and Genome Editing.
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- Angewandte Chemie, 2023, v. 135, n. 25, p. 1, doi. 10.1002/ange.202303973
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- Article
A Conformational Restriction Strategy for the Control of CRISPR/Cas Gene Editing with Photoactivatable Guide RNAs**.
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- Angewandte Chemie, 2023, v. 135, n. 5, p. 1, doi. 10.1002/ange.202212413
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- Article
A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria.
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- Angewandte Chemie, 2022, v. 134, n. 37, p. 1, doi. 10.1002/ange.202206168
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Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold.
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- Angewandte Chemie, 2022, v. 134, n. 32, p. 1, doi. 10.1002/ange.202205409
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- Article
Yujun Song.
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- Angewandte Chemie, 2021, v. 133, n. 42, p. 22792, doi. 10.1002/ange.202111150
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- Article
Hypoxia‐Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild‐Photothermal Therapy.
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- Angewandte Chemie, 2021, v. 133, n. 39, p. 21370, doi. 10.1002/ange.202107036
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Binding‐Mediated Formation of Ribonucleoprotein Corona for Efficient Delivery and Control of CRISPR/Cas9.
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- Angewandte Chemie, 2021, v. 133, n. 20, p. 11204, doi. 10.1002/ange.202014162
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Spatiotemporal Delivery of CRISPR/Cas9 Genome Editing Machinery Using Stimuli‐Responsive Vehicles.
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- Angewandte Chemie, 2021, v. 133, n. 16, p. 8679, doi. 10.1002/ange.202005644
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- Article
Hierarchical Self‐assembly of Discrete Metal–Organic Cages into Supramolecular Nanoparticles for Intracellular Protein Delivery.
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- Angewandte Chemie, 2021, v. 133, n. 10, p. 5489, doi. 10.1002/ange.202013904
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An Unexpected Split‐Merge Pathway in the Assembly of the Symmetric Nonribosomal Peptide Antibiotic Closthioamide.
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- Angewandte Chemie, 2021, v. 133, n. 8, p. 4150, doi. 10.1002/ange.202011741
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Insect‐Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non‐Canonical Polyketide Chain Termination.
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- Angewandte Chemie, 2020, v. 132, n. 51, p. 23322, doi. 10.1002/ange.202005711
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