Works matching DE "GENOME editing"

Results: 5000

A murine model lacking Lyst recapitulates Chediak-Higashi syndrome with an earlier-onset neurodegenerative phenotype.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08482-1

By:

Greene, Sunny;
Talbert, Mackenzie L.;
Frost, F. Graeme;
Zerfas, Patricia M.;
Springer, Danielle;
Noguchi, Audrey;
Morimoto, Marie;
Maynard, Dawn;
Garrett, Lisa;
Elliot, Gene;
Traver, Maria;
Yarnell, David;
Leoyklang, Petcharat;
Burke, John D.;
Nicoli, Elena-Raluca;
Gahl, William A.;
Introne, Wendy J.;
Malicdan, May Christine V.

Publication type:

Article

Beyond the lab: future-proofing agriculture for climate resilience and stress management.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1565850

By:

Pehlivan, Necla;
Altaf, Muhammad Tanveer;
Emamverdian, Abolghassem;
Ghorbani, Abazar

Publication type:

Article

Refined CRISPR/Cas9 genome editing in the pea aphid uncovers the essential roles of Laccase2 in overwintering egg adaptation.

Published in:

PLoS Genetics, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.pgen.1011557

By:

Shigenobu, Shuji;
Yoda, Shinichi;
Ohsawa, Sonoko;
Suzuki, Miyuzu

Publication type:

Article

SMARCA5 is required for the development of granule cell neuron precursors and Sonic Hedgehog Medulloblastoma growth.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11857-3

By:

Tsiami, Foteini;
Drwesh, Layla;
Surender, Surender;
Fitzgerald, Julia;
Schittenhelm, Jens;
Picketts, David J.;
Segal, Rosalind A.;
Tabatabai, Ghazaleh;
Merk, Daniel J.

Publication type:

Article

Off-target sequence variations driven by the intrinsic properties of the Cas–sgRNA–DNA complex in genome editing.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0328905

By:

Kurniawan, Celine;
Itoh, Takeshi

Publication type:

Article

An ALOG transcription factor targets a TALE homeobox gene during corolla abscission in Torenia fournieri.

Published in:

New Phytologist, 2025, v. 247, n. 4, p. 1912, doi. 10.1111/nph.70291

By:

Li, Jiahuizi;
Li, Binghou;
Zhou, Xuan;
Ma, Xiaofang;
Xie, Ruohan;
Sun, Yufei;
Su, Shihao

Publication type:

Article

Going bananas: how transgene‐free editing is contributing to a fruitful future.

Published in:

New Phytologist, 2025, v. 247, n. 4, p. 1557, doi. 10.1111/nph.70150

By:

Hoengenaert, Lennart;
Anders, Chantal;
Boerjan, Wout

Publication type:

Article

An Agrobacterium‐mediated base editing approach generates transgene‐free edited banana.

Published in:

New Phytologist, 2025, v. 247, n. 4, p. 1790, doi. 10.1111/nph.70044

By:

Van den Broeck, Senne;
Ngapout, Yvan;
Panis, Bart;
Vanderschuren, Hervé

Publication type:

Article

TREM1 is essential for maintaining stemness of liver cancer stem-like cells in hepatocellular carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1618342

By:

Sreekumar, Arsha;
Ajith, Ashwin;
Mamouni, Kenza;
Horuzsko, Daniel D.;
Horuzsko, Anatolij

Publication type:

Article

CRISPR-Cas9 Technology: in Biotechnology a Breakthrough Innovation.

Published in:

Journal of Animal Production / Hayvansal Üretim, 2025, v. 66, n. 1, p. 91, doi. 10.29185/hayuretim.1628222

By:

ÖZANATÇA, Lara;
ISIK KALPAR, Raziye

Publication type:

Article

Advances in Therapeutic Applications of CRISPR Genome Editing for Spinal Pain Management.

Published in:

Neurospine, 2025, v. 22, n. 2, p. 421, doi. 10.14245/ns.2550462.231

By:

Kang, Chan Young;
Been, Kyung Wook;
Kang, Myoung-Hee;
Choi, Myung Su;
Kang, Rae Hee;
Hur, Junseok W.;
Hur, Junho K.

Publication type:

Article

Protein kinase CK2 contributes to glucose homeostasis.

Published in:

Biological Chemistry, 2025, v. 406, n. 3/4, p. 69, doi. 10.1515/hsz-2024-0158

By:

Götz, Claudia;
Montenarh, Mathias

Publication type:

Article

AI-Powered CRISPR-Cas9: Precision Therapeutics for ATP7B Mutations in Wilson Disease and Restoring Copper Metabolism.

Published in:

Cuestiones de Fisioterapia, 2025, v. 54, n. 4, p. 667

By:

Thalib, Husna Irfan;
Muzammil, Aleesha;
Alotaibi, Sarah Abdullah;
Dahroug, Aya Sami;
Alnuwaimi, Meral;
Shams, Farrah

Publication type:

Article

Revolutionizing Precision Medicine: Novel Strategies to Combat Multi-Drug Resistant Bacteria.

Published in:

Cuestiones de Fisioterapia, 2024, v. 53, n. 3, p. 3216

By:

Bangash, Sudhair Abbas;
Rasool, Ghazala;
Ibnidris Almisbah, Hafiz Osman;
Ahmed Sulaiman, Ahmed Hamad;
Ud Din Shah, Syed Shahab;
Khyzer, Ehtisham

Publication type:

Article

ETHICAL CHALLENGES IN BIOTECHNOLOGY: EXPLORING THE BOUNDARIES OF SCIENTIFIC INTERVENTION.

Published in:

Synesis, 2025, v. 17, n. 1, p. 1

By:

VARYPAIEV, OLEXII;
SEROHINA, NATALIIA;
SEREDIUK, NATALIIA;
DOROZHKO, IRYNA;
SILVESTROVA, OKSANA

Publication type:

Article

DNA Synthesis and Assembly Technologies: From Oligonucleotides to Complete Genomes.

Published in:

Chinese Journal of Chemistry, 2025, v. 43, n. 16, p. 2069, doi. 10.1002/cjoc.202401134

By:

Tan, Wei;
Jia, Xuemei;
Liu, Ying;
Yao, Chi;
Yang, Dayong

Publication type:

Article

Disrupting ZBTB7A or BCL11A binding sites reactivates fetal hemoglobin in erythroblasts from healthy and β<sup>0</sup>-thalassemia/HbE individuals.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10791-8

By:

Wongborisuth, Chokdee;
Innachai, Pawarit;
Saisawang, Chonticha;
Tubsuwan, Alisa;
Jearawiriyapaisarn, Natee;
Kaewprommal, Pavita;
Piriyapongsa, Jittima;
Chiangjong, Wararat;
Anurathapan, Usanarat;
Songdej, Duantida;
Tangprasittipap, Amornrat;
Hongeng, Suradej

Publication type:

Article

Generation of NOD SCID mice with near-complete deletions of Il2rg and Prkdc for human cancer and HSC engraftment.

Published in:

Transgenic Research, 2025, v. 34, n. 1, p. 1, doi. 10.1007/s11248-025-00454-9

By:

Kim, You-Min;
Na, Hee Ju;
Kwon, Do Hee;
Lee, Jae Hoon;
Park, Bo Min;
Lee, Subin;
Nam, Tae Wook;
Park, Mi Yeon;
Park, Sun Ha;
Kim, Sung Joo;
Choi, Bongkum;
Lee, Han-Woong

Publication type:

Article

The shape of discovery: a journey through genetics, coevolution, and a scientific life Open Access.

Published in:

Genetics, 2025, v. 230, n. 3, p. 1, doi. 10.1093/genetics/iyaf096

By:

Whiteman, Noah K

Publication type:

Article

Targeted seed EMS mutagenesis reveals a basic helix–loop–helix transcription factor underlying male sterility in sorghum Open Access.

Published in:

Genetics, 2025, v. 230, n. 3, p. 1, doi. 10.1093/genetics/iyaf017

By:

Xiao, Yuguo;
Khangura, Rajdeep S;
Wang, Zhonghui;
Dilkes, Brian P;
Eveland, Andrea L

Publication type:

Article

Establishment and rescue of fibroblast cell lines carrying a nonsense mutation of RB1 by CRISPR-based base editing.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10600-2

By:

Jung, Youngri;
Seo, Eunhee;
Yang, Soyeon;
Bae, Sangsu;
Kim, Jeong Hun;
Jang, Hyeon-ki;
Jo, Dong Hyun

Publication type:

Article

The regulatory role of ZmSTOMAGEN1/2 in maize stomatal development is elucidated via gene editing and metabolic profiling.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0328433

By:

Xu, Juan-Juan;
Chen, Qing-Yun;
Qin, Li-Fang;
Liu, Yuan;
Li, You-Zhi;
Fan, Xian-Wei

Publication type:

Article

Enhancing rufomycin production by CRISPR/Cas9-based genome editing and promoter engineering in Streptomyces sp. MJM3502.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 421, doi. 10.1016/j.synbio.2025.01.002

By:

Chun Su;
Nguyen-Quang Tuan;
Wen-Hua Li;
Jin-Hua Cheng;
Ying-Yu Jin;
Soon-Kwang Hong;
Hyun Lee;
Qader, Mallique;
Klein, Larry;
Shetye, Gauri;
Pauli, Guido F.;
Flanzblau, Scott G.;
Sang-Hyun Cho;
Xin-Qing Zhao;
Joo-Won Suh

Publication type:

Article

Development of CRISPR-Cas9-based genome editing tools for non-model microorganism Erwinia persicina.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 555, doi. 10.1016/j.synbio.2025.02.006

By:

Tingfeng Cheng;
Xinyan Cao;
Yuchen Wang;
Lei Zhao

Publication type:

Article

Developing safe and efficient CGBE editor based on Cas-embedding strategy.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 504, doi. 10.1016/j.synbio.2025.02.001

By:

Tian Lin;
Xin Wang;
Yu Zhang;
Guanglei Li;
Xingxu Huang;
Ming Shi

Publication type:

Article

CRISPR-Cas9-based one-step multiplexed genome editing through optimizing guide RNA processing strategies in Pichia pastoris.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 484, doi. 10.1016/j.synbio.2025.01.005

By:

Kaidi Chen;
Maimaitirexiati, Gulikezi;
Qiannan Zhang;
Yi Li;
Xiangjian Liu;
Hongting Tang;
Xiang Gao;
Bo Wang;
Tao Yu;
Shuyuan Guo

Publication type:

Article

CRISPR/Cas9-based iterative multi-copy integration for improved metabolite yields in Saccharomyces cerevisiae.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 629, doi. 10.1016/j.synbio.2025.02.016

By:

Ximei Chen;
Chenyang Li;
Xin Qiu;
Ming Chen;
Yongping Xu;
Shuying Li;
Qian Li;
Liang Wang

Publication type:

Article

Coupling genome-wide continuous perturbation with biosensor screening reveals the potential targets in yeast isopentanol synthesis network.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 452, doi. 10.1016/j.synbio.2024.12.010

By:

Qi Xiao;
Jingjing Shi;
Lixian Wang;
Guoping Zhao;
Yanfei Zhang

Publication type:

Article

Application of multiple genomic-editing technologies in Streptomyces fungicidicus for improved enduracidin yield.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 564, doi. 10.1016/j.synbio.2025.02.008

By:

Yanan Sun;
Guoguo Wu;
Yining Wang;
Jipeng Jiang;
Haikuan Wang;
Fufeng Liu;
Fuping Lu;
Huitu Zhang

Publication type:

Article

Human Germline Genome Editing, 10 Years On.

Published in:

2025

By:

Cwik, Bryan

Publication type:

Opinion

CRISPR/Cas9-Mediated gene disruption: A novel strategy against fall armyworm.

Published in:

Farming & Management, 2025, v. 10, n. 1, p. 55, doi. 10.31830/2456-8724.2025.FM-155

By:

DODIYA, RAVIKUMAR D.;
ITALIYA, JAY V.;
PATEL, PRAKASH S.;
PATHAN, NAZIYA P.;
BARAD, ANILKUMAR H.

Publication type:

Article

Asparagine Synthetase Gene OsASN2 Is Crucial for Rice Seed Development and Germination.

Published in:

Plants (2223-7747), 2025, v. 14, n. 13, p. 1999, doi. 10.3390/plants14131999

By:

Hu, Rui;
Liang, Kaiming;
Hu, Xiangyu;
Li, Meijuan;
Ye, Qunhuan;
Yin, Yuanhong;
Tang, Cai;
Wang, Xinyu;
Fu, Youqiang;
Pan, Junfeng;
Zhang, Mingyong;
Zhong, Xuhua

Publication type:

Article

Engineering High-Amylose and High-Dietary-Fibre Barley Grains Through Multiplex Genome Editing of Four Starch-Synthetic Genes.

Published in:

Foods, 2025, v. 14, n. 13, p. 2319, doi. 10.3390/foods14132319

By:

Yang, Qiang;
Ral, Jean-Philippe;
Jiang, Qiantao;
Li, Zhongyi

Publication type:

Article

VrJAZ1和VrJAZ12在绿豆对群结腐霉抗性中的功能研究.

Published in:

Journal of Nanjing Agricultural University / Nanjuing Nongye Daxue Xuebao, 2025, v. 48, n. 3, p. 581, doi. 10.7685/jnau.202312045

By:

胡亚群;
闫强;
周琰琰;
武婷;
郑豫;
王瑞敏;
薛冬;
袁星星;
陈新

Publication type:

Article

Exploration of Multi-Source Lignocellulose-Degrading Microbial Resources and Bioaugmentation Strategies: Implications for Rumen Efficiency.

Published in:

Animals (2076-2615), 2025, v. 15, n. 13, p. 1920, doi. 10.3390/ani15131920

By:

Lv, Xiaokang;
Qiao, Zhanhong;
Chen, Chao;
Hua, Jinling;
Zhou, Chuanshe

Publication type:

Article

PrimeNet: rational design of Prime editing pegRNAs by deep learning Open Access.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 3, p. 1, doi. 10.1093/bib/bbaf293

By:

Liao, Xichen;
Liu, Qi;
Chuai, Guohui

Publication type:

Article

The role of lncRNA in plant growth and domestication.

Published in:

Transcription (2154-1264), 2025, v. 16, n. 2/3, p. 169, doi. 10.1080/21541264.2025.2473224

By:

Gahlaut, Vijay;
Jaiswal, Vandana

Publication type:

Article

Transthyretin Amyloid Cardiomyopathy—2025 Update: Current Diagnostic Approaches and Emerging Therapeutic Options.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4785, doi. 10.3390/jcm14134785

By:

Tschöpe, Carsten;
Elsanhoury, Ahmed;
Kristen, Arnt V.

Publication type:

Article

The Nuclear Transcription Factor SlNF-YC9 Regulates the Protrusion of Tomato Fruit Tip.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6511, doi. 10.3390/ijms26136511

By:

Gao, Zihan;
Long, Ting;
Guo, Pengyu;
Luo, Junjie;
Nie, Xiaoqian;
Xie, Qiaoli;
Chen, Guoping;
Hu, Zongli

Publication type:

Article

Mutant p53 as a Therapeutic Target: The Report of Its Death Was an Exaggeration.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6446, doi. 10.3390/ijms26136446

By:

Toledo, Franck

Publication type:

Article

Molecular Determinants of TMC Protein Biogenesis and Trafficking.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6356, doi. 10.3390/ijms26136356

By:

Shao, Dedong;
Tan, Jinru;
Fan, Xiaozhi;
Shu, Yilai;
Qu, Qianhui;
Tang, Yi-Quan

Publication type:

Article

Functional Genomics: From Soybean to Legume.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6323, doi. 10.3390/ijms26136323

By:

Zhou, Can;
Wang, Haiyan;
Zhu, Xiaobin;
Li, Yuqiu;
Zhang, Bo;
Tadege, Million;
Wu, Shihao;
Qi, Zhaoming;
Xia, Zhengjun

Publication type:

Article

Stem Cell Therapy Approaches for Ischemia: Assessing Current Innovations and Future Directions.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6320, doi. 10.3390/ijms26136320

By:

Ma, Changguo;
Yu, An;
He, Tingyan;
Qian, Yulin;
Hu, Min

Publication type:

Article

Therapeutic Approaches for C9ORF72-Related ALS: Current Strategies and Future Horizons.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6268, doi. 10.3390/ijms26136268

By:

Cattaneo, Marco;
Giagnorio, Eleonora;
Lauria, Giuseppe;
Marcuzzo, Stefania

Publication type:

Article

A Novel Regulatory Role for RPS4Y1 in Inflammatory and Fibrotic Processes.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6213, doi. 10.3390/ijms26136213

By:

Reddy, Karosham D.;
Rathnayake, Senani N. H.;
Idrees, Sobia;
Boedijono, Fia;
Xenaki, Dikaia;
Padula, Matthew P.;
Berge, Maarten van den;
Faiz, Alen;
Oliver, Brian G. G.

Publication type:

Article

Exploring the Role of Peripheral Macrophages in Glioma Progression: The Metabolic Significance of Cyclooxygenase-2 (COX-2).

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6198, doi. 10.3390/ijms26136198

By:

Pietzsch, Jens;
Toussaint, Magali;
Donat, Cornelius Kurt;
Doctor, Alina;
Meister, Sebastian;
Wodtke, Johanna;
Laube, Markus;
Hofheinz, Frank;
Rix, Jan;
Deuther-Conrad, Winnie;
Haase-Kohn, Cathleen

Publication type:

Article

Multi-Omics Integration: Predicting Progression and Optimizing Clinical Treatment of Hepatocellular Carcinoma Through Malignant-Cell-Related Genes.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6135, doi. 10.3390/ijms26136135

By:

Wang, Qianwen;
Cheng, Lingli;
Yan, Honglin;
Yuan, Jingping

Publication type:

Article

Bitter Taste Receptor TAS2R43 Co-Regulates Mechanisms of Gastric Acid Secretion and Zinc Homeostasis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6017, doi. 10.3390/ijms26136017

By:

Orth, H. Noreen;
Pirkwieser, Philip;
Benthin, Julia;
Koehler, Melanie;
Sterneder, Sonja;
Parlar, Etkin;
Schaudy, Erika;
Lietard, Jory;
Michel, Timm;
Boger, Valerie;
Dunkel, Andreas;
Somoza, Mark M.;
Somoza, Veronika

Publication type:

Article

Combating Antimicrobial Resistance by Resensitising Bacteria to Antibiotics Using CRISPR: A Narrative Review.

Published in:

Apollo Medicine, 2025, v. 22, n. 4, p. 336, doi. 10.1177/09760016241290651

By:

Nair, Harihara Sujit

Publication type:

Article

The Turning Point: A Framework of Considerations for Reforming Human Gene Editing Laws in New Zealand.

Published in:

Te Mata Koi: Auckland University Law Review, 2024, v. 30, p. 137

By:

HYE-SONG GOO

Publication type:

Article