Works matching DE "GENETIC pleiotropy"

Results: 683

Analysis of multiple related phenotypes in genome-wide association studies.

Published in:

Journal of Bioinformatics & Computational Biology, 2016, v. 14, n. 5, p. -1, doi. 10.1142/S0219720016440054

By:

Oh, Sohee;
Huh, Iksoo;
Lee, Seung Yeoun;
Park, Taesung

Publication type:

Article

Transgene-induced pleiotropic effects in transplastomic plants.

Published in:

Biotechnology Letters, 2014, v. 36, n. 2, p. 229, doi. 10.1007/s10529-013-1356-6

By:

Scotti, N.;
Cardi, T.

Publication type:

Article

Intra-population variability in the drought response of a beech (Fagus sylvatica L.) population in the southwest of Europe.

Published in:

Tree Physiology, 2017, v. 37, n. 7, p. 938, doi. 10.1093/treephys/tpx058

By:

Aranda, Ismael;
Bahamonde, Hector A.;
Sánchez-Gómez, David

Publication type:

Article

Biochemical and molecular profiling of unknown olive genotypes from central Italy: determination of major and minor components.

Published in:

European Food Research & Technology, 2019, v. 245, n. 1, p. 83, doi. 10.1007/s00217-018-3142-0

By:

Mousavi, Soraya;
Stanzione, Vitale;
Mencuccini, Massimo;
Baldoni, Luciana;
Bufacchi, Marina;
Mariotti, Roberto

Publication type:

Article

Relationship between immune cells and diabetic nephropathy: a Mendelian randomization study.

Published in:

Acta Diabetologica, 2024, v. 61, n. 10, p. 1251, doi. 10.1007/s00592-024-02293-2

By:

Li, Xin;
Zhang, Liangyou;
Yan, Chuang;
Zeng, Huo;
Chen, Gangyi;
Qiu, Jianwen

Publication type:

Article

Genetic overlap between Parkinson's disease and inflammatory bowel disease.

Published in:

Brain Communications, 2023, v. 5, n. 1, p. 1, doi. 10.1093/braincomms/fcad002

By:

Xiaoying Kang;
Ploner, Alexander;
Yunzhang Wang;
Ludvigsson, Jonas F.;
Williams, Dylan M.;
Pedersen, Nancy L.;
Wirdefeldt, Karin

Publication type:

Article

Accounting for spatially heterogeneous conditions in local‐scale surveillance strategies: case study of the biosecurity insect pest, grape phylloxera (Daktulosphaira vitifoliae (Fitch)).

Published in:

Pest Management Science, 2018, v. 74, n. 12, p. 2724, doi. 10.1002/ps.5057

By:

Triska, Maggie D;
Powell, Kevin S;
Collins, Cassandra;
Pearce, Inca;
Renton, Michael

Publication type:

Article

ALS herbicide resistance mutations in Raphanus raphanistrum: evaluation of pleiotropic effects on vegetative growth and ALS activity.

Published in:

Pest Management Science, 2013, v. 69, n. 6, p. 689, doi. 10.1002/ps.3419

By:

Li, Mei;
Yu, Qin;
Han, Heping;
Vila‐Aiub, Martin;
Powles, Stephen B

Publication type:

Article

The Structure-To-Function Relationships of Gammaherpesvirus-Encoded Long Non-Coding RNAs and Their Contributions to Viral Pathogenesis.

Published in:

Non-Coding RNA, 2018, v. 4, n. 4, p. 1, doi. 10.3390/ncrna4040024

By:

Chavez-Calvillo, Gabriela;
Martin, Sarah;
Hamm, Chad;
Sztuba-Solinska, Joanna

Publication type:

Article

Investigation of the anti‐skin aging effects of taurine through mendelian randomization analysis of its relationship with immune cells.

Published in:

Journal of Cosmetic Dermatology, 2024, v. 23, n. 12, p. 4295, doi. 10.1111/jocd.16515

By:

Liu, Hongtao;
Zheng, Honglai;
Zhou, Siyuan;
Lin, Quan

Publication type:

Article

A weighted method for the exclusive hypothesis test with application to typhoon data.

Published in:

Canadian Journal of Statistics, 2021, v. 49, n. 4, p. 1258, doi. 10.1002/cjs.11618

By:

Wang, Yi;
Wu, Peng;
Tong, Xingwei;
Sun, Jianguo

Publication type:

Article

Glycated Serum Protein Genetics and Pleiotropy with Cardiometabolic Risk Factors.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/2310235

By:

Johnson, Matthew P.;
Keyho, Ryan;
Blackburn, Nicholas B.;
Laston, Sandra;
Kumar, Satish;
Peralta, Juan;
Thapa, Suman S.;
Towne, Bradford;
Subedi, Janardan;
Blangero, John;
Williams-Blangero, Sarah

Publication type:

Article

A genome-wide association study of multiple longitudinal traits with related subjects.

Published in:

Stat, 2016, v. 5, n. 1, p. 22, doi. 10.1002/sta4.102

By:

Sung, Yubin;
Feng, Zeny;
Subedi, Sanjeena

Publication type:

Article

Update of genetic variants in CEP120 and CC2D2A—With an emphasis on genotype‐phenotype correlations, tissue specific transcripts and exploring mutation specific exon skipping therapies.

Published in:

Molecular Genetics & Genomic Medicine, 2021, v. 9, n. 12, p. 1, doi. 10.1002/mgg3.1603

By:

Barroso‐Gil, Miguel;
Olinger, Eric;
Ramsbottom, Simon A.;
Molinari, Elisa;
Miles, Colin G.;
Sayer, John A.

Publication type:

Article

Whole‐exome sequencing for variant discovery in blepharospasm.

Published in:

Molecular Genetics & Genomic Medicine, 2018, v. 6, n. 4, p. 601, doi. 10.1002/mgg3.411

By:

Tian, Jun;
Vemula, Satya R.;
Xiao, Jianfeng;
Valente, Enza Maria;
Defazio, Giovanni;
Petrucci, Simona;
Gigante, Angelo Fabio;
Rudzińska‐Bar, Monika;
Wszolek, Zbigniew K.;
Kennelly, Kathleen D.;
Uitti, Ryan J.;
van Gerpen, Jay A.;
Hedera, Peter;
Trimble, Elizabeth J.;
LeDoux, Mark S.

Publication type:

Article

46,XY disorder of sexual development resulting from a novel monoallelic mutation (p.Ser31Phe) in the steroid 5 α-reductase type-2 ( SRD5A2) gene.

Published in:

Molecular Genetics & Genomic Medicine, 2014, v. 2, n. 4, p. 292, doi. 10.1002/mgg3.76

By:

Chávez, Bertha;
Ramos, Luis;
Gómez, Rita;
Vilchis, Felipe

Publication type:

Article

Aberrant Notch signalling contributes to hypertrophic scar formation by modulating the phenotype of keratinocytes.

Published in:

Experimental Dermatology, 2016, v. 25, n. 2, p. 137, doi. 10.1111/exd.12897

By:

Li, Bing;
Gao, Chao;
Diao, Jian‐Sheng;
Wang, Da‐Lei;
Chu, Fei‐Fei;
Li, Yang;
Wang, Gang;
Guo, Shu‐Zhong;
Xia, Wei

Publication type:

Article

Surgery for constipation: systematic review and practice recommendations.

Published in:

Colorectal Disease, 2017, v. 19, p. 17, doi. 10.1111/codi.13779

By:

Knowles, C. H.;
Grossi, U.;
Chapman, M.;
Mason, J.;
Brown, Steven;
Campbell, Kenneth;
Clarke, Andrew;
Cruickshank, Neil;
Dixon, Anthony;
Emmett, Christopher;
Hooper, Richard;
Horrocks, Emma;
Lacy‐Colson, Jon;
Lindsey, Ian;
Mercer‐Jones, Mark;
Miller, Andrew;
Pares, David;
Pilkington, Sophie;
Smart, Neil;
Stevens, Natasha

Publication type:

Article

The Association of CYP19A1 Variation with Circulating Estradiol and Aromatase Inhibitor Outcome: Can CYP19A1 Variants Be Used to Predict Treatment Efficacy?

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00218

By:

Glubb, Dylan M.;
O'Mara, Tracy A.;
Shamsani, Jannah;
Spurdle, Amanda B.

Publication type:

Article

Pleiotropic virulence factor - Streptococcus pyogenes fibronectin-binding proteins.

Published in:

Cellular Microbiology, 2013, v. 15, n. 4, p. 503, doi. 10.1111/cmi.12083

By:

Yamaguchi, Masaya;
Terao, Yutaka;
Kawabata, Shigetada

Publication type:

Article

Statin pleiotropy prevents rho kinase-mediated intestinal epithelial barrier compromise induced by Blastocystis cysteine proteases.

Published in:

Cellular Microbiology, 2012, v. 14, n. 9, p. 1474, doi. 10.1111/j.1462-5822.2012.01814.x

By:

Mirza, Haris;
Wu, Zhaona;
Teo, Joshua D. W.;
Tan, Kevin S. W.

Publication type:

Article

Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46817-4

By:

Tissink, E. P.;
Shadrin, A. A.;
van der Meer, D.;
Parker, N.;
Hindley, G.;
Roelfs, D.;
Frei, O.;
Fan, C. C.;
Nagel, M.;
Nærland, T.;
Budisteanu, M.;
Djurovic, S.;
Westlye, L. T.;
van den Heuvel, M. P.;
Posthuma, D.;
Kaufmann, T.;
Dale, A. M.;
Andreassen, O. A.

Publication type:

Article

Prediction of Mutations to Control Pathways Enabling Tumor Cell Invasion with the CoLoMoTo Interactive Notebook (Tutorial).

Published in:

Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.00787

By:

Levy, Nicolas;
Naldi, Aurélien;
Hernandez, Céline;
Stoll, Gautier;
Thieffry, Denis;
Zinovyev, Andrei;
Calzone, Laurence;
Paulevé, Loïc

Publication type:

Article

Renoprotective effects of incretin-based drugs: A novel pleiotropic effect of dipeptidyl peptidase-4 inhibitor.

Published in:

Journal of Diabetes Investigation, 2016, v. 7, n. 1, p. 29, doi. 10.1111/jdi.12380

By:

Kodera, Ryo;
Shikata, Kenichi

Publication type:

Article

Visfatin and resistin: Mediators of the pleiotropic effects of incretins?

Published in:

Journal of Diabetes Investigation, 2012, v. 3, n. 5, p. 427, doi. 10.1111/j.2040-1124.2012.00235.x

By:

Nakashima, Eitaro

Publication type:

Article

A cautionary note on using Mendelian randomization to examine the Barker hypothesis and Developmental Origins of Health and Disease (DOHaD).

Published in:

Journal of Developmental Origins of Health & Disease, 2021, v. 12, n. 5, p. 688, doi. 10.1017/S2040174420001105

By:

D'Urso, Shannon;
Wang, Geng;
Hwang, Liang-Dar;
Moen, Gunn-Helen;
Warrington, Nicole M.;
Evans, David M.

Publication type:

Article

Sooty Wing Phenotype Found in Offspring of a Wild-Caught Female of Eurema mandarina (Lepidoptera: Pieridae).

Published in:

Journal of the Lepidopterists' Society, 2016, v. 70, n. 3, p. 201, doi. 10.18473/107.070.0305

By:

Kageyama, Daisuke

Publication type:

Article

Epigenetic considerations of the AOPE gene.

Published in:

Biomolecular Concepts, 2015, v. 6, n. 1, p. 77, doi. 10.1515/bmc-2014-0039

By:

Chang-En Yu;
Foraker, Jessica

Publication type:

Article

The MAPT p.P301L mutation presents as a rare early-onset corticobasal syndrome: A case report.

Published in:

Neurology Asia, 2023, v. 28, n. 1, p. 211, doi. 10.54029/2023ejf

By:

Cheng-Hsuan Li;
Ni-Chung Lee;
Kun-Ju Lin;
Ing-Tsung Hsiao;
Yi-Hsin Weng;
Chin-Hsien Lin

Publication type:

Article

The MAPT p.P301L mutation presents as a rare early-onset corticobasal syndrome: A case report.

Published in:

Neurology Asia, 2023, v. 28, n. 1, p. 211, doi. 10.54029/2023ejf

By:

Cheng-Hsuan Li;
Ni-Chung Lee;
Kun-Ju Lin;
Ing-Tsung Hsiao;
Yi-Hsin Weng;
Chin-Hsien Lin

Publication type:

Article

Extending Causality Tests with Genetic Instruments: An Integration of Mendelian Randomization with the Classical Twin Design.

Published in:

Behavior Genetics, 2018, v. 48, n. 4, p. 337, doi. 10.1007/s10519-018-9904-4

By:

Minică, Camelia C.;
Dolan, Conor V.;
Boomsma, Dorret I.;
de Geus, Eco;
Neale, Michael C.

Publication type:

Article

Pleiotropic Effects of DDT Resistance on Male Size and Behaviour.

Published in:

Behavior Genetics, 2017, v. 47, n. 4, p. 449, doi. 10.1007/s10519-017-9850-6

By:

Rostant, Wayne;
Bowyer, Jemima;
Coupland, Jack;
Hosken, David;
Wedell, Nina;
Facey, James

Publication type:

Article

Attention Deficit Hyperactivity Disorder Symptoms and Low Educational Achievement: Evidence Supporting A Causal Hypothesis.

Published in:

Behavior Genetics, 2017, v. 47, n. 3, p. 278, doi. 10.1007/s10519-017-9836-4

By:

de Zeeuw, Eveline;
van Beijsterveldt, Catharina;
Ehli, Erik;
de Geus, Eco;
Boomsma, Dorret

Publication type:

Article

Apolipoprotein E ε Allele Modulates the Immediate Impact of Acute Exercise on Prefrontal Function.

Published in:

Behavior Genetics, 2015, v. 45, n. 1, p. 106, doi. 10.1007/s10519-014-9675-5

By:

De Marco, Matteo;
Clough, Peter;
Dyer, Charlotte;
Vince, Rebecca;
Waby, Jennifer;
Midgley, Adrian;
Venneri, Annalena

Publication type:

Article

DNA Evidence for Strong Genome-Wide Pleiotropy of Cognitive and Learning Abilities.

Published in:

Behavior Genetics, 2013, v. 43, n. 4, p. 267, doi. 10.1007/s10519-013-9594-x

By:

Trzaskowski, Maciej;
Davis, Oliver;
DeFries, John;
Yang, Jian;
Visscher, Peter;
Plomin, Robert

Publication type:

Article

Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.

Published in:

Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00220

By:

Drange, Ole Kristian;
Smeland, Olav Bjerkehagen;
Shadrin, Alexey A.;
Finseth, Per Ivar;
Witoelar, Aree;
Frei, Oleksandr;
Wang, Yunpeng;
Hassani, Sahar;
Djurovic, Srdjan;
Dale, Anders M.;
Andreassen, Ole A.;
Stahl, Eli A;
Breen, Gerome;
Forstner, Andreas J;
McQuillin, Andrew;
Ripke, Stephan;
Trubetskoy, Vassily;
Mattheisen, Manuel;
Coleman, Jonathan R I;
Gaspar, Heìleìna A

Publication type:

Article

In search of morphological modules: a systematic review.

Published in:

Biological Reviews, 2017, v. 92, n. 3, p. 1332, doi. 10.1111/brv.12284

By:

Esteve‐Altava, Borja

Publication type:

Article

Condition-dependence, pleiotropy and the handicap principle of sexual selection in melanin-based colouration.

Published in:

Biological Reviews, 2016, v. 91, n. 2, p. 328, doi. 10.1111/brv.12171

By:

Roulin, Alexandre

Publication type:

Article

On the fate of sexual traits under asexuality.

Published in:

Biological Reviews, 2014, v. 89, n. 4, p. 805, doi. 10.1111/brv.12078

By:

van der Kooi, Casper J.;
Schwander, Tanja

Publication type:

Article

Genetic explorations of recent human metabolic adaptations: hypotheses and evidence.

Published in:

Biological Reviews, 2012, v. 87, n. 4, p. 838, doi. 10.1111/j.1469-185X.2012.00227.x

By:

Brown, Elizabeth A.

Publication type:

Article

Genetic pleiotropy and the shared pathological features of corticobasal degeneration and progressive supranuclear palsy: a case report and a review of the literature.

Published in:

2021

By:

Rini, James;
Asken, Breton;
Geier, Ethan;
Rankin, Katherine;
Kramer, Joel;
Boxer, Adam;
Miller, Bruce;
Yokoyama, Jennifer;
Spina, Salvatore

Publication type:

journal article

Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation.

Published in:

2017

By:

Qin Wang;
Holmes, Michael V.;
Smith, George Davey;
Ala-Korpela, Mika;
Wang, Qin;
Davey Smith, George

Publication type:

journal article

RARS2 mutations in a sibship with infantile spasms.

Published in:

Epilepsia (Series 4), 2016, v. 57, n. 5, p. e97, doi. 10.1111/epi.13358

By:

Ngoh, Adeline;
Bras, Jose;
Guerreiro, Rita;
Meyer, Esther;
McTague, Amy;
Dawson, Eleanor;
Mankad, Kshitij;
Gunny, Roxana;
Clayton, Peter;
Mills, Philippa B.;
Thornton, Rachel;
Lai, Ming;
Forsyth, Robert;
Kurian, Manju A.

Publication type:

Article

Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness.

Published in:

Molecular Systems Biology, 2015, v. 11, n. 1, p. n/a, doi. 10.15252/msb.20145264

By:

Bauer, Christopher R;
Li, Shuang;
Siegal, Mark L

Publication type:

Article

Multifunctional genes.

Published in:

Molecular Systems Biology, 2005, v. 1, n. 1, p. E1, doi. 10.1038/msb4100006

By:

van de Peppel, Jeroen;
Holstege, Frank C P

Publication type:

Article

Gene regulatory network architecture in different developmental contexts influences the genetic basis of morphological evolution.

Published in:

PLoS Genetics, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.pgen.1007375

By:

Kittelmann, Sebastian;
Buffry, Alexandra D.;
Franke, Franziska A.;
Almudi, Isabel;
Yoth, Marianne;
Sabaris, Gonzalo;
Couso, Juan Pablo;
Nunes, Maria D. S.;
Frankel, Nicolás;
Gómez-Skarmeta, José Luis;
Pueyo-Marques, Jose;
Arif, Saad;
McGregor, Alistair P.

Publication type:

Article

A quadratically regularized functional canonical correlation analysis for identifying the global structure of pleiotropy with NGS data.

Published in:

PLoS Computational Biology, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pcbi.1005788

By:

Lin, Nan;
Zhu, Yun;
Fan, Ruzong;
Xiong, Momiao

Publication type:

Article

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study.

Published in:

PLoS Medicine, 2015, v. 12, n. 8, p. 1, doi. 10.1371/journal.pmed.1001866

By:

Mokry, Lauren E.;
Ross, Stephanie;
Ahmad, Omar S.;
Forgetta, Vincenzo;
Smith, George Davey;
Leong, Aaron;
Greenwood, Celia M. T.;
Thanassoulis, George;
Richards, J. Brent

Publication type:

Article

Pleiotropic Constraints, Expression Level, and the Evolution of miRNA Sequences.

Published in:

Journal of Molecular Evolution, 2013, v. 77, n. 5/6, p. 206, doi. 10.1007/s00239-013-9588-6

By:

Jovelin, Richard

Publication type:

Article

More than a co-incidence? Comment on: Amyotrophic lateral sclerosis is over‐represented in two Huntington's disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT gene expansion.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 2, p. 257, doi. 10.1007/s00401-022-02517-1

By:

Bakels, Hannah S.;
Feleus, Stephanie;
van Dis, Vera;
de Bot, Susanne T.

Publication type:

Article