Works about GENETIC overexpression

Results: 5000

ACSS2 mediates an epigenetic pathway to regulate β-cell adaptation during gestation in mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58322-3

By:

Zhang, Yu;
He, Shuang;
Wang, Xi;
Wang, Xin;
He, Mao-Yang;
Yu, Xin-Xin;
Xu, Cheng-Ran

Publication type:

Article

Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata.

Published in:

EvoDevo, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13227-025-00243-9

By:

Warner, Jacob F.;
Besemer, Ryan;
Schickle, Alicia;
Borbee, Erin;
Changsut, Isabella V.;
Sharp, Koty;
Babonis, Leslie S.

Publication type:

Article

AHNAK2 confers 5-fluorouracil resistance in colorectal cancer via activation of the AKT/GSK-3β signaling axis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01682-3

By:

Xie, Mianjiao;
Lin, Wanlin;
Du, Yongtao;
Li, Yunlong;
Li, Shisen

Publication type:

Article

New insights into Eragrostis curvula 's sexual and apomictic reproductive development.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1530855

By:

Pasten, María Cielo;
Carballo, José;
Díaz, Alejandra Raquel;
Mizzotti, Chiara;
Cucinotta, Mara;
Colombo, Lucia;
Echenique, Viviana Carmen;
Mendes, Marta Adelina

Publication type:

Article

miR-145-5p modulates CDCA3 to overcome gemcitabine resistance in pancreatic cancer.

Published in:

General Physiology & Biophysics, 2025, v. 44, n. 2, p. 175, doi. 10.4149/gpb_2024047

By:

Jiayun Ge;
Zhihong Zhang;
Guohui Shao;
Dong Wei;
Bo Tang;
Zhitian Shi;
Renchao Zou;
Xin Wang

Publication type:

Article

Enhancement of spinosad production in Saccharopolyspora spinosa by overexpression of the complete 74-kb spinosyn gene cluster.

Published in:

Microbial Cell Factories, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12934-025-02724-x

By:

Gan, Lu;
Zhang, Zhengyu;
Chen, Jingtao;
Shen, Zhichun;
Chen, Wujie;
Chen, Shaoxin;
Li, Jiyang

Publication type:

Article

The comparison of life compatibility between trisomy 2 and trisomy 21 (Down syndrome) by bioinformatic-based databases.

Published in:

European Research Journal, 2025, v. 11, n. 3, p. 527, doi. 10.18621/eurj.1583797

By:

Şahin, Elif İlknur;
Nalkıran, İhsan;
Uzuner, Selcen Çelik

Publication type:

Article

木聚糖水解酶基因 RcXYNC 调控月季黑斑病抗性的研究.

Published in:

Biotechnology Bulletin, 2025, v. 41, n. 4, p. 211, doi. 10.13560/j.cnki.biotech.bull.1985.2024-0766

By:

苏琳;
戚雨岑;
杨艺;
程和丰;
纪思雨;
刘婷;
程堂仁;
王佳;
张启翔;
潘会堂

Publication type:

Article

水稻蔗糖转运蛋白 OsSUT4 基因的克隆与功能分析.

Published in:

Journal of Henan Agricultural Sciences, 2025, v. 54, n. 3, p. 1

By:

蔡昱萌;
汪颖;
何飞;
刘燕清;
刘静妍;
郭彦丽;
孙玥;
苏京平;
王胜军;
李军玲

Publication type:

Article

谷氨酰胺合成酶与运动发酵单胞菌耐受酚醛的关系.

Published in:

Journal of Changzhou University (Natural Science Edition) / Changzhou Daxue Xuebao (Ziran Kexue Ban), 2025, v. 37, n. 1, p. 48, doi. 10.3969/j.issn.2095-0411.2025.01.006

By:

易霞;
张盟;
王一龙;
蒙顾;
王心悦;
何玉财;
朱劼

Publication type:

Article

Mechanistic study of modulating mitochondrial fission and fusion to ameliorate neuropathic pain in mice.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99300-5

By:

Xie, Liu;
Cao, Jing;
Xu, Yiran;
Yang, Qingqing;
Chang, Wanting;
Song, Linna;
Sun, Yanyan

Publication type:

Article

Homeostasis of Calnexin Is Essential for the Growth, Virulence, and Hypovirus RNA Accumulation in the Chestnut Blight Fungus.

Published in:

Molecular Microbiology, 2025, v. 123, n. 5, p. 393, doi. 10.1111/mmi.15348

By:

Huang, Tao;
Ma, Xiaoling;
Zhao, Ziqi;
Qin, Danna;
Qin, Weiye;
Wang, Jinzi;
Chen, Baoshan;
He, Xipu

Publication type:

Article

Overexpression of miR-181a regulates the Warburg effect in triple-negative breast cancer.

Published in:

Climacteric, 2023, v. 26, n. 1, p. 64, doi. 10.1080/13697137.2022.2147821

By:

Wang, Y.;
Tahiri, H.;
Yang, C.;
Gu, M.;
Ruan, X.;
Hardy, P.

Publication type:

Article

Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells.

Published in:

Advanced Functional Materials, 2017, v. 27, n. 31, p. n/a, doi. 10.1002/adfm.201701027

By:

Zhang, Ruili;
Gao, Shi;
Wang, Zhongliang;
Han, Da;
Liu, Lin;
Ma, Qingjie;
Tan, Weihong;
Tian, Jie;
Chen, Xiaoyuan

Publication type:

Article

Overexpression of chloroplastic Zea mays NADP-malic enzyme (ZmNADP-ME) confers tolerance to salt stress in Arabidopsis thaliana.

Published in:

Photosynthesis Research, 2023, v. 158, n. 1, p. 57, doi. 10.1007/s11120-023-01041-x

By:

Kandoi, Deepika;
Tripathy, Baishnab C.

Publication type:

Article

Towards efficient photosynthesis: overexpression of Zea mays phosphoenolpyruvate carboxylase in Arabidopsis thaliana.

Published in:

Photosynthesis Research, 2016, v. 130, n. 1-3, p. 47, doi. 10.1007/s11120-016-0224-3

By:

Kandoi, Deepika;
Mohanty, Sasmita;
Govindjee;
Tripathy, Baishnab

Publication type:

Article

Role of isopentenyl-diphosphate isomerase in heterologous cyanobacterial ( Synechocystis) isoprene production.

Published in:

Photosynthesis Research, 2016, v. 130, n. 1-3, p. 517, doi. 10.1007/s11120-016-0293-3

By:

Chaves, Julie;
Romero, Paloma;
Kirst, Henning;
Melis, Anastasios

Publication type:

Article

Overexpression of an Aeluropus littoralis Parl. potassium transporter gene, AlHAK1, in cotton enhances potassium uptake and salt tolerance.

Published in:

Euphytica, 2015, v. 203, n. 1, p. 197, doi. 10.1007/s10681-014-1310-2

By:

Liu, J.;
Zhang, S.;
Tang, H.;
Dong, L.;
Wu, L.;
Liu, L.;
Che, W.

Publication type:

Article

OsHox4 regulates GA signaling by interacting with DELLA-like genes and GA oxidase genes in rice.

Published in:

Euphytica, 2015, v. 201, n. 1, p. 97, doi. 10.1007/s10681-014-1191-4

By:

Zhou, Wei;
Malabanan, Paul;
Abrigo, Editha

Publication type:

Article

Multiple gene integration to promote erythritol production on glycerol in Yarrowia lipolytica.

Published in:

Biotechnology Letters, 2021, v. 43, n. 7, p. 1277, doi. 10.1007/s10529-021-03113-1

By:

Zhang, Ling;
Nie, Ming-Yue;
Liu, Feng;
Chen, Jun;
Wei, Liu-Jing;
Hua, Qiang

Publication type:

Article

Increasing the pyruvate pool by overexpressing phosphoenolpyruvate carboxykinase or triosephosphate isomerase enhances phloroglucinol production in Escherichia coli.

Published in:

Biotechnology Letters, 2020, v. 42, n. 4, p. 633, doi. 10.1007/s10529-020-02812-5

By:

Liu, Wen;
Zhang, Rubing;
Wei, Manman;
Cao, Yujin;
Xian, Mo

Publication type:

Article

Hac1p homologues from higher eukaryotes can improve the secretion of heterologous proteins in the yeast Pichia pastoris.

Published in:

Biotechnology Letters, 2018, v. 40, n. 7, p. 1149, doi. 10.1007/s10529-018-2571-y

By:

Bankefa, Olufemi Emmanuel;
Wang, Meiyu;
Zhu, Taicheng;
Li, Yin

Publication type:

Article

Overexpression of Sirtuin2 prevents high glucose-induced vascular endothelial cell injury by regulating the p53 and NF-κB signaling pathways.

Published in:

Biotechnology Letters, 2018, v. 40, n. 2, p. 271, doi. 10.1007/s10529-017-2487-y

By:

Zhang, Wenguang;
Liu, Dongmei;
Ren, Jianzhuang;
Zhou, Pengli;
Han, Xinwei

Publication type:

Article

Overexpression and RNA interference of <italic>TwDXR</italic> regulate the accumulation of terpenoid active ingredients in <italic>Tripterygium wilfordii</italic>.

Published in:

Biotechnology Letters, 2018, v. 40, n. 2, p. 419, doi. 10.1007/s10529-017-2484-1

By:

Zhang, Yifeng;
Zhao, Yujun;
Wang, Jiadian;
Hu, Tianyuan;
Tong, Yuru;
Zhou, Jiawei;
Song, Yadi;
Gao, Wei;
Huang, Luqi

Publication type:

Article

Enhanced biomass and oxidative stress tolerance of Synechococcus elongatus PCC 7942 overexpressing the DHAR gene from Brassica juncea.

Published in:

Biotechnology Letters, 2017, v. 39, n. 10, p. 1499, doi. 10.1007/s10529-017-2382-6

By:

Kim, Young-Saeng;
Kim, Il-Sup;
Boyd, Joseph;
Taton, Arnaud;
Golden, James;
Yoon, Ho-Sung

Publication type:

Article

miR-34a attenuates glioma cells progression and chemoresistance via targeting PD-L1.

Published in:

Biotechnology Letters, 2017, v. 39, n. 10, p. 1485, doi. 10.1007/s10529-017-2397-z

By:

Wang, Yi;
Wang, Li

Publication type:

Article

Enhancement of 5-aminolevulinic acid production by metabolic engineering of the glycine biosynthesis pathway in Corynebacterium glutamicum.

Published in:

Biotechnology Letters, 2017, v. 39, n. 9, p. 1369, doi. 10.1007/s10529-017-2362-x

By:

Zou, Yalan;
Chen, Tao;
Feng, Lili;
Zhang, Shuanghong;
Xing, Dongxu;
Wang, Zhiwen

Publication type:

Article

MiR-338-3p inhibits TNF-α-induced lipogenesis in human sebocytes.

Published in:

Biotechnology Letters, 2017, v. 39, n. 9, p. 1343, doi. 10.1007/s10529-017-2369-3

By:

Liu, Jia;
Cao, Linggai;
Feng, Yue;
Li, Yuhua;
Li, Tao

Publication type:

Article

Combinatorial analysis of enzymatic bottlenecks of l-tyrosine pathway by p-coumaric acid production in Saccharomyces cerevisiae.

Published in:

Biotechnology Letters, 2017, v. 39, n. 7, p. 977, doi. 10.1007/s10529-017-2322-5

By:

Mao, Jiwei;
Liu, Quanli;
Song, Xiaofei;
Wang, Hesuiyuan;
Feng, Hui;
Xu, Haijin;
Qiao, Mingqiang

Publication type:

Article

Co-expression of l-glutamate oxidase and catalase in Escherichia coli to produce α-ketoglutaric acid by whole-cell biocatalyst.

Published in:

Biotechnology Letters, 2017, v. 39, n. 6, p. 913, doi. 10.1007/s10529-017-2314-5

By:

Liu, Qingdai;
Ma, Xiaoqian;
Cheng, Haijiao;
Xu, Ning;
Liu, Jun;
Ma, Yanhe

Publication type:

Article

Candida guilliermondii as a potential biocatalyst for the production of long-chain α,ω-dicarboxylic acids.

Published in:

Biotechnology Letters, 2017, v. 39, n. 3, p. 429, doi. 10.1007/s10529-016-2264-3

By:

Werner, Nicole;
Dreyer, Miriam;
Wagner, Wenke;
Papon, Nicolas;
Rupp, Steffen;
Zibek, Susanne

Publication type:

Article

MicroRNA-1284 inhibits proliferation and induces apoptosis in SGC-7901 human gastric cancer cells.

Published in:

Biotechnology Letters, 2017, v. 39, n. 1, p. 33, doi. 10.1007/s10529-016-2213-1

By:

Huang, Mingwei;
Wu, Liucheng;
Luo, Shanshan;
Qin, Haiquan;
Yang, Yang;
Chen, Jiansi;
Li, Zhao;
Qin, Yuzhou

Publication type:

Article

A reductase gene mppE controls yellow component production in azaphilone polyketide pathway of Monascus.

Published in:

Biotechnology Letters, 2017, v. 39, n. 1, p. 163, doi. 10.1007/s10529-016-2232-y

By:

Balakrishnan, Bijinu;
Park, Si-Hyung;
Kwon, Hyung-Jin

Publication type:

Article

Down-regulation of microRNA-126-5p contributes to overexpression of VEGFA in lipopolysaccharide-induced acute lung injury.

Published in:

Biotechnology Letters, 2016, v. 38, n. 8, p. 1277, doi. 10.1007/s10529-016-2107-2

By:

Tang, Rurong;
Pei, Ling;
Bai, Tao;
Wang, Junke

Publication type:

Article

Boosting fatty acid synthesis in Rhodococcus opacus PD630 by overexpression of autologous thioesterases.

Published in:

Biotechnology Letters, 2016, v. 38, n. 6, p. 999, doi. 10.1007/s10529-016-2072-9

By:

Huang, Luxuan;
Zhao, Lina;
Zan, Xinyi;
Song, Yuanda;
Ratledge, Colin

Publication type:

Article

Expression, purification and characterization of a thermostable leucine dehydrogenase from the halophilic thermophile Laceyella sacchari.

Published in:

Biotechnology Letters, 2016, v. 38, n. 5, p. 855, doi. 10.1007/s10529-016-2053-z

By:

Zhu, Wenjun;
Li, Yan;
Jia, Honghua;
Wei, Ping;
Zhou, Hua;
Jiang, Min

Publication type:

Article

Metabolic engineering of Saccharomyces cerevisiae for linalool production.

Published in:

Biotechnology Letters, 2016, v. 38, n. 3, p. 503, doi. 10.1007/s10529-015-2000-4

By:

Amiri, Pegah;
Shahpiri, Azar;
Asadollahi, Mohammad;
Momenbeik, Fariborz;
Partow, Siavash

Publication type:

Article

Engineering of a hybrid route to enhance shikimic acid production in Corynebacterium glutamicum.

Published in:

Biotechnology Letters, 2015, v. 37, n. 9, p. 1861, doi. 10.1007/s10529-015-1852-y

By:

Zhang, Bo;
Jiang, Cheng-Ying;
Liu, Yi-Ming;
Liu, Chang;
Liu, Shuang-Jiang

Publication type:

Article

Purification of proteins from solutions containing residual host cell proteins via preparative crystallization.

Published in:

Biotechnology Letters, 2015, v. 37, n. 9, p. 1791, doi. 10.1007/s10529-015-1866-5

By:

Hekmat, Dariusch;
Breitschwerdt, Peter;
Weuster-Botz, Dirk

Publication type:

Article

Enhancement of phenyllactic acid biosynthesis by recognition site replacement of D-lactate dehydrogenase from Lactobacillus pentosus.

Published in:

Biotechnology Letters, 2015, v. 37, n. 6, p. 1233, doi. 10.1007/s10529-015-1778-4

By:

Zhu, Yibo;
Hu, Fagen;
Zhu, Yingyue;
Wang, Limei;
Qi, Bin

Publication type:

Article

Enhanced production of poly-3-hydroxybutyrate by Escherichia coli over-expressing multiple copies of NAD kinase integrated in the host genome.

Published in:

Biotechnology Letters, 2015, v. 37, n. 6, p. 1273, doi. 10.1007/s10529-015-1797-1

By:

Zhang, Jie;
Gao, Xue;
Hong, Peng-Hui;
Li, Zheng-Jun;
Tan, Tian-Wei

Publication type:

Article

Comparative proteome analysis of global effect of POS5 and zwf- ppnK overexpression in l-isoleucine producing Corynebacterium glutamicum ssp. lactofermentum.

Published in:

Biotechnology Letters, 2015, v. 37, n. 5, p. 1063, doi. 10.1007/s10529-015-1768-6

By:

Shi, Feng;
Li, Kun;
Li, Yongfu

Publication type:

Article

Lentivirus-mediated Wnt10b overexpression enhances fracture healing in a rat atrophic non-union model.

Published in:

Biotechnology Letters, 2015, v. 37, n. 3, p. 733, doi. 10.1007/s10529-014-1703-2

By:

Gao, Feng;
Zhang, Chang-qing;
Chai, Yi-min;
Li, Xiao-lin

Publication type:

Article

Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14.

Published in:

Antonie van Leeuwenhoek, 2016, v. 109, n. 6, p. 737, doi. 10.1007/s10482-016-0675-8

By:

Pletzer, Daniel;
Braun, Yvonne;
Weingart, Helge

Publication type:

Article

A novel d-amino acid oxidase from a contaminated agricultural soil metagenome and its characterization.

Published in:

Antonie van Leeuwenhoek, 2015, v. 107, n. 6, p. 1615, doi. 10.1007/s10482-015-0457-8

By:

Ou, Qian;
Liu, Yao;
Deng, Jie;
Chen, Gao;
Yang, Ying;
Shen, Peihong;
Wu, Bo;
Jiang, Chengjian

Publication type:

Article

SAHA could inhibit TGF-β1/p38 pathway in MI-induced cardiac fibrosis through DUSP4 overexpression.

Published in:

Heart & Vessels, 2022, v. 37, n. 1, p. 152, doi. 10.1007/s00380-021-01900-4

By:

Wang, Kaihao;
Tang, Ruijie;
Wang, Siyuan;
Wang, Wenyao;
Zhang, Kuo;
Li, Jun;
Li, Ping;
Tang, Yi-Da

Publication type:

Article

Cytoprotective effects of transgenic neuroglobin overexpression in an acute and chronic mouse model of ischemic heart disease.

Published in:

Heart & Vessels, 2018, v. 33, n. 1, p. 80, doi. 10.1007/s00380-017-1065-5

By:

Luyckx, Evi;
Everaert, Bert R.;
Van der Veken, Bieke;
Van Leuven, Wendy;
Timmermans, Jean-Pierre;
Vrints, Christiaan J.;
De Meyer, Guido R. Y.;
Martinet, Wim;
Dewilde, Sylvia

Publication type:

Article

HER2 overexpression is associated with worse outcomes in patients with upper tract urothelial carcinoma (UTUC).

Published in:

World Journal of Urology, 2017, v. 35, n. 2, p. 251, doi. 10.1007/s00345-016-1871-x

By:

Soria, Francesco;
Moschini, Marco;
Haitel, Andrea;
Wirth, Gregory;
Karam, Jose;
Wood, Christopher;
Rouprêt, Morgan;
Margulis, Vitaly;
Karakiewicz, Pierre;
Briganti, Alberto;
Raman, Jay;
Kammerer-Jacquet, Solene-Florence;
Mathieu, Romain;
Bensalah, Karim;
Lotan, Yair;
Özsoy, Mehmet;
Remzi, Mesut;
Gust, Kilian;
Shariat, Shahrokh

Publication type:

Article

Overexpression of PTP4A3 is associated with metastasis and unfavorable prognosis in bladder cancer.

Published in:

World Journal of Urology, 2016, v. 34, n. 6, p. 835, doi. 10.1007/s00345-015-1698-x

By:

Yeh, Hsin-Chih;
Huang, Chun-Nung;
Li, Ching-Chia;
Chang, Lin-Li;
Lin, Hui-Hui;
Ke, Hung-Lung;
Huang, A-Mei;
Liang, Peir-In;
Li, Chien-Feng;
Wu, Wen-Jeng

Publication type:

Article

βIII-tubulin overexpression is linked to aggressive tumor features and shortened survival in clear cell renal cell carcinoma.

Published in:

World Journal of Urology, 2015, v. 33, n. 10, p. 1561, doi. 10.1007/s00345-014-1463-6

By:

Quaas, Alexander;
Rahvar, Amir-Hossein;
Burdelski, Christoph;
Koop, Christina;
Eichelberg, Christian;
Rink, Michael;
Dahlem, Roland;
Schlomm, Thorsten;
Tsourlakis, Maria;
Simon, Ronald;
Minner, Sarah;
Sauter, Guido;
Steurer, Stefan

Publication type:

Article