Works about GENETIC load

Results: 708

The relationships between impulsivity and mood in bipolar disorder: An ecological momentary assessment study.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0314963

By:

Ramírez-Martín, Almudena;
Sirignano, Lea;
Foo, Jerome C.;
Streit, Fabian;
Frank, Josef;
Witt, Stephanie H.;
Rietschel, Marcella;
Mayoral-Cleries, Fermin;
Moreno-Küstner, Berta;
Guzmán-Parra, Jose

Publication type:

Article

Functional Bias and Spatial Organization of Genes in Mutational Hot and Cold Regions in the Human Genome.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 1, doi. 10.1371/journal.pbio.0020029

By:

Chuang, Jeffrey H;
Li, Hao

Publication type:

Article

Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C.

Published in:

Liver International, 2004, v. 24, n. 4, p. 285, doi. 10.1111/j.1478-3231.2004.0928.x

By:

Geier, Andreas;
Reugels, Michael;
Weiskirchen, Ralf;
Wasmuth, Hermann E.;
Dietrich, Christoph G.;
Siewert, Elmar;
Gartung, Carsten;
Lorenzen, Johann;
Bosserhoff, Anja K.;
Brügmann, Marc;
Gressner, Axel M.;
Matern, Siegfried;
Lammert, Frank

Publication type:

Article

Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07986-0

By:

Dussex, Nicolas;
Jansson, Ingela;
van der Valk, Tom;
Packer, Craig;
Norman, Anita;
Kissui, Bernard M.;
E. Mjingo, Ernest;
Spong, Göran

Publication type:

Article

The dynamics of prebiotic take-off: the transfer of functional RNA communities from mineral surfaces to vesicles.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07841-2

By:

Vörös, Dániel;
Czárán, Tamás;
Szilágyi, András;
Könnyű, Balázs

Publication type:

Article

Challenges in AAV-Based Retinal Gene Therapies and the Role of Magnetic Nanoparticle Platforms.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 23, p. 7385, doi. 10.3390/jcm13237385

By:

Siontas, Oliver;
Ahn, Seungkuk

Publication type:

Article

Genetic inbreeding depression load for fertility traits in Pura Raza Española mares.

Published in:

Journal of Animal Science, 2021, v. 99, n. 12, p. 1, doi. 10.1093/jas/skab316

By:

Perdomo-González, Davinia I;
Molina, Antonio;
Sánchez-Guerrero, María J;
Bartolomé, Ester;
Varona, Luis;
Valera, Mercedes

Publication type:

Article

Analysis of founder-specific inbreeding depression on birth weight in Ripollesa lambs.

Published in:

Journal of Animal Science, 2009, v. 87, n. 1, p. 72, doi. 10.2527/jas.2008-0897

By:

Casellas, J.;
Piedrafita, J.;
Caja, G.;
Varona, L.

Publication type:

Article

Inbreeding and genetic load in a pair of sibling grouse species: Tetrastes sewersowi and T. bonasia.

Published in:

Avian Research, 2024, v. 15, p. 1, doi. 10.1016/j.avrs.2024.100184

By:

Kai Song;
van der Valk, Tom;
Bin Gao;
Halvarsson, Peter;
Yun Fang;
Wendong Xie;
Klaus, Siegfried;
Zhiming Han;
Yue-Hua Sun;
Höglund, Jacob

Publication type:

Article

Copy Number Variation and Frequency of rs179008 in Gene Associated with Systemic Lupus Erythematosus in Two Mexican Populations.

Published in:

2022

By:

Pacheco, Guillermo Valencia;
Nakazawa Ueji, Yumi E.;
Bello, Julián Ramírez;
Barbosa Cobos, Rosa E.;
Jiménez Becerra, Eduardo D.;
González Herrera, Lizbeth J.;
Pérez Mendoza, Gerardo J.;
Rivero Cárdenas, Nubia A.;
Angulo Ramírez, Angélica V.;
López Villanueva, Ricardo F.

Publication type:

journal article

Post-meiotic mechanism of facultative parthenogenesis in gonochoristic whiptail lizard species.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.97035

By:

Ho, David V.;
Tormey, Duncan;
Odell, Aaron;
Newton, Aracely A.;
Schnittker, Robert R.;
Baumann, Diana P.;
Neaves, William B.;
Schroeder, Morgan R.;
Sigauke, Rutendo F.;
Barley, Anthony J.;
Baumann, Peter

Publication type:

Article

Population genetic structure, differentiation, and diversity in Tetrix subulata pygmy grasshoppers: roles of population size and immigration.

Published in:

Ecology & Evolution (20457758), 2016, v. 6, n. 21, p. 7831, doi. 10.1002/ece3.2520

By:

Tinnert, Jon;
Hellgren, Olof;
Lindberg, Jenny;
Koch‐Schmidt, Per;
Forsman, Anders

Publication type:

Article

Crosstalk of lactate metabolism-related subtypes, establishment of a prognostic signature and immune infiltration characteristics in colon adenocarcinoma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98735-0

By:

Xu, Wenwei;
Li, Yongjian;
Zeng, Zhaoshang;
Guo, Guanjun

Publication type:

Article

The chromosome-scale genome of Magnolia sinica (Magnoliaceae) provides insights into the conservation of plant species with extremely small populations (PSESP).

Published in:

GigaScience, 2024, v. 13, n. 1, p. 1, doi. 10.1093/gigascience/giad110

By:

Cai, Lei;
Liu, Detuan;
Yang, Fengmao;
Zhang, Rengang;
Yun, Quanzheng;
Dao, Zhiling;
Ma, Yongpeng;
Sun, Weibang

Publication type:

Article

Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2007, v. 32, n. 5, p. 505, doi. 10.1111/j.1365-2710.2007.00850.x

By:

Li, D.;
Lu, W.;
Zhu, J.-Y.;
Gao, J.;
Lou, Y.-Q.;
Zhang, G.-L.

Publication type:

Article

Single-cell and bulk RNA sequencing analysis of B cell marker genes in TNBC TME landscape and immunotherapy.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1245514

By:

Fangrui Zhao;
Chen Zhao;
Tangpeng Xu;
Yanfang Lan;
Huiqing Lin;
Xiaofei Wu;
Xiangpan Li

Publication type:

Article

PD-1 blockade and radiotherapy combination for advanced Epstein-Barr virus-associated intrahepatic cholangiocarcinoma: a case report and literature review.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1239168

By:

Chun-Xu Liao;
Chang-Song Deng;
Xia Liang;
Jian-Chuan Yang;
Zhi-Zhong Chen;
Xiao-Ying Lin;
Cai-Feng Lin;
Shen Chen;
Song-Song Wu

Publication type:

Article

Recent Consanguinity and Outbred Autozygosity Are Associated With Increased Risk of Late-Onset Alzheimer's Disease.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.629373

By:

Napolioni, Valerio;
Scelsi, Marzia A.;
Khan, Raiyan R.;
Altmann, Andre;
Greicius, Michael D.

Publication type:

Article

Genetic Diversity, Inbreeding Level, and Genetic Load in Endangered Snub-Nosed Monkeys (Rhinopithecus).

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.615926

By:

Kuang, Weimin;
Hu, Jingyang;
Wu, Hong;
Fen, Xiaotian;
Dai, Qingyan;
Fu, Qiaomei;
Xiao, Wen;
Frantz, Laurent;
Roos, Christian;
Nadler, Tilo;
Irwin, David M.;
Zhou, Linchun;
Yang, Xu;
Yu, Li

Publication type:

Article

Genomics of Otitis Media (OM): Molecular Genetics Approaches to Characterize Disease Pathophysiology.

Published in:

Frontiers in Genetics, 2020, v. 11, p. 1, doi. 10.3389/fgene.2020.00313

By:

Giese, Arnaud P. J.;
Ali, Saadat;
Isaiah, Amal;
Aziz, Ishrat;
Riazuddin, Saima;
Ahmed, Zubair M.

Publication type:

Article

Do multiple families alter estimates of risk for age-related cataract in a population-based study?

Published in:

Ophthalmic Epidemiology, 2003, v. 10, n. 2, p. 97, doi. 10.1076/opep.10.2.97.13896

By:

Klein, Barbara E.K.;
Klein, Ronald;
Lee, Kristine E.;
Moore, Emily L.

Publication type:

Article

SPINK5 gene mutation and decreased LEKTI activity in three Chinese patients with Netherton's syndrome.

Published in:

Clinical & Experimental Dermatology, 2007, v. 32, n. 5, p. 564, doi. 10.1111/j.1365-2230.2007.02438.x

By:

Zhao, Y.;
Ma, Z. H.;
Yang, Y.;
Yang, S. X.;
Wu, L. S.;
Ding, B. L.;
Lin, Z. M.;
Wang, A. P.;
Bu, D. F.;
Tu, P.

Publication type:

Article

Successful intubation using video laryngoscope in a child with CHARGE syndrome - A case report -.

Published in:

Anesthesia & Pain Medicine, 2019, v. 14, n. 1, p. 40, doi. 10.17085/apm.2019.14.1.40

By:

Jeongho Kim;
Jeong In Hong;
Kyoung-lin Chae;
Kyoung Sub Yoon;
Sang Yoong Park;
Seung-Cheol Lee;
Jong-Hwan Lee;
Chan Jong Chung;
So Ron Choi

Publication type:

Article

Incorporating genetic load contributes to predicting Arabidopsis thaliana's response to climate change.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58021-z

By:

Jiang, Juan;
Chen, Jia-Fu;
Li, Xin-Tong;
Wang, Li;
Mao, Jian-Feng;
Wang, Bao-Sheng;
Guo, Ya-Long

Publication type:

Article

Incorporating genetic load contributes to predicting Arabidopsis thaliana's response to climate change.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58021-z

By:

Jiang, Juan;
Chen, Jia-Fu;
Li, Xin-Tong;
Wang, Li;
Mao, Jian-Feng;
Wang, Bao-Sheng;
Guo, Ya-Long

Publication type:

Article

Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57435-z

By:

Sprockett, Daniel D.;
Dillard, Brian A.;
Landers, Abigail A.;
Sanders, Jon G.;
Moeller, Andrew H.

Publication type:

Article

The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53079-7

By:

Jamsandekar, Minal;
Ferreira, Mafalda S.;
Pettersson, Mats E.;
Farrell, Edward D.;
Davis, Brian W.;
Andersson, Leif

Publication type:

Article

Genomic adaptation to small population size and saltwater consumption in the critically endangered Cat Ba langur.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52811-7

By:

Zhang, Liye;
Leonard, Neahga;
Passaro, Rick;
Luan, Mai Sy;
Van Tuyen, Pham;
Han, Le Thi Ngoc;
Cam, Nguyen Huy;
Vogelnest, Larry;
Lynch, Michael;
Fine, Amanda E.;
Nga, Nguyen Thi Thanh;
Van Long, Nguyen;
Rawson, Benjamin M.;
Behie, Alison;
Van Nguyen, Truong;
Le, Minh D.;
Nadler, Tilo;
Walter, Lutz;
Marques-Bonet, Tomas;
Hofreiter, Michael

Publication type:

Article

Heavy genetic load associated with the subspecific differentiation of japonica rice (Oryza sativa ssp. japonica L.).

Published in:

Journal of Experimental Botany, 2006, v. 57, n. 11, p. 2815, doi. 10.1093/jxb/erl046

By:

Jian-Long Xu;
Jun-Min Wang;
Ye-Qing Sun;
Li-Jun Wei;
Rong-Ting Luo;
Ming-Xian Zhang;
Zhi-Kang Li

Publication type:

Article

Imunoterapie karcinomů hlavy a krku.

Published in:

Otorhinolaryngology & Phoniatrics / Otorinolaryngologie a Foniatrie, 2024, v. 73, n. 4, p. 233

By:

Pavelková, L.;
Bonaventurová, M.;
Plzák, J.;
Fialová, A.

Publication type:

Article

INBREEDING DEPRESSION AND PARTITIONING OF GENETIC LOAD IN THE INVASIVE BIENNIAL ALLIARIA PETIOLATA (BRASSICACEAE).

Published in:

American Journal of Botany, 2013, v. 100, n. 3, p. 509, doi. 10.3732/ajb.1200403

By:

Mullarkey, Alicia A.;
Byers, Diane L.;
Anderson, Roger C.

Publication type:

Article

REPRODUCTIVE BIOLOGY OF THREE FERN SPECIES MAY CONTRIBUTE TO DIFFERENTIAL COLONIZATION SUCCESS IN POST-AGRICULTURAL FORESTS.

Published in:

American Journal of Botany, 2006, v. 93, n. 9, p. 1289, doi. 10.3732/ajb.93.9.1289

By:

Flinn, Kathryn M.

Publication type:

Article

Severity ranking of non-deletional alpha thalassemic alleles: insights from an Omani family study.

Published in:

European Journal of Haematology, 2011, v. 86, n. 6, p. 507, doi. 10.1111/j.1600-0609.2011.01606.x

By:

Wali, Yasser;
Zadjali, Shoaib Al;
Elshinawy, Mohamed;
Beshlawi, Ismail;
Fawaz, Naglaa;
AlKindi, Salam;
Rawas, Abdulhakim;
Alsinani, Siham;
Daar, Shahina;
Krishnamoorthy, Rajagopal

Publication type:

Article

A case of mast cell leukaemia with exon 9 KIT mutation and good response to imatinib.

Published in:

European Journal of Haematology, 2011, v. 86, n. 6, p. 531, doi. 10.1111/j.1600-0609.2011.01598.x

By:

Mital, Andrzej;
Piskorz, Anna;
Lewandowski, Krzysztof;
Wasąg, Bartosz;
Limon, Janusz;
Hellmann, Andrzej

Publication type:

Article

Tumor genetic heterogeneity analysis of chronic sun‐damaged melanoma.

Published in:

Pigment Cell & Melanoma Research, 2020, v. 33, n. 3, p. 480, doi. 10.1111/pcmr.12851

By:

Sanna, Adriana;
Harbst, Katja;
Johansson, Iva;
Christensen, Gustav;
Lauss, Martin;
Mitra, Shamik;
Rosengren, Frida;
Häkkinen, Jari;
Vallon‐Christersson, Johan;
Olsson, Håkan;
Ingvar, Åsa;
Isaksson, Karolin;
Ingvar, Christian;
Nielsen, Kari;
Jönsson, Göran

Publication type:

Article

Efficacy of liquid biopsy for disease monitoring and early prediction of tumor progression in EGFR mutation-positive non-small cell lung cancer.

Published in:

PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0267362

By:

Ho, Hsiang-Ling;
Jiang, Yuqiu;
Chiang, Chi-Lu;
Karwowska, Sylwia;
Yerram, Ranga;
Sharma, Keerti;
Scudder, Sidney;
Chiu, Chao-Hua;
Tsai, Chun-Ming;
Palma, John F.;
Sharma, Abha;
Chou, Teh-Ying

Publication type:

Article

Correlation analysis of m<sup>6</sup>A-modified regulators with immune microenvironment infiltrating cells in lung adenocarcinoma.

Published in:

PLoS ONE, 2022, v. 17, n. 2, p. 1, doi. 10.1371/journal.pone.0264384

By:

Ye, Wei;
Huang, Tianpeng

Publication type:

Article

Frequency Distribution of Q188R, N314D, Duarte 1, and Duarte 2 GALT Variant Alleles in an Indian Galactosemia Population.

Published in:

Biochemical Genetics, 2012, v. 50, n. 11/12, p. 871, doi. 10.1007/s10528-012-9527-z

By:

Singh, Ramandeep;
Thapa, Babu;
Kaur, Gurjit;
Prasad, Rajendra

Publication type:

Article

Neural correlates of reward processing in healthy siblings of patients with schizophrenia.

Published in:

Frontiers in Human Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnhum.2015.00504

By:

Hanssen, Esther;
van der Velde, Jorien;
Gromann, Paula M.;
Shergill, Sukhi S.;
de Haan, Lieuwe;
Bruggeman, Richard;
Krabbendam, Lydia;
Aleman, André;
van Atteveldt, Nienke

Publication type:

Article

Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BRCA2 mutation: evidence for lower uptake in women affected by breast cancer and older women.

Published in:

British Journal of Cancer, 2012, v. 106, n. 4, p. 775, doi. 10.1038/bjc.2011.573

By:

Sidon, L;
Ingham, S;
Clancy, T;
Clayton, R;
Clarke, A;
Jones, E A;
Lalloo, F;
Evans, D G R

Publication type:

Article

Mitochondrial point heteroplasmy: insights from deep-sequencing of human replicate samples.

Published in:

BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-09963-z

By:

Korolija, Marina;
Sukser, Viktorija;
Vlahoviček, Kristian

Publication type:

Article

'GENETIC LOAD' and changes in the chronology of early mortality in mini-pigs of ICG SB RAS.

Published in:

Agronomy Research, 2020, v. 18, n. 3, p. 2156, doi. 10.15159/AR.20.171

By:

Nikitin, S. V.;
Shatokhin, K. S.;
Zaporozhets, V. I.;
Kochnev, N. N.;
Bashur, D. S.;
Khodakova, A. V.;
Ermolaev, V. I.

Publication type:

Article

A Flp-SUMO hybrid recombinase reveals multi-layered copy number control of a selfish DNA element through post-translational modification.

Published in:

PLoS Genetics, 2019, v. 15, n. 6, p. 1, doi. 10.1371/journal.pgen.1008193

By:

Ma, Chien-Hui;
Su, Bo-Yu;
Maciaszek, Anna;
Fan, Hsiu-Fang;
Guga, Piotr;
Jayaram, Makkuni

Publication type:

Article

Deleterious variation shapes the genomic landscape of introgression.

Published in:

PLoS Genetics, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.pgen.1007741

By:

Kim, Bernard Y.;
Huber, Christian D.;
Lohmueller, Kirk E.

Publication type:

Article

Plasmid diversity in arctic strains of Psychrobacter spp.

Published in:

Extremophiles, 2013, v. 17, n. 3, p. 433, doi. 10.1007/s00792-013-0521-0

By:

Dziewit, Lukasz;
Cegielski, Adrian;
Romaniuk, Krzysztof;
Uhrynowski, Witold;
Szych, Antoni;
Niesiobedzki, Pawel;
Zmuda-Baranowska, Magdalena;
Zdanowski, Marek;
Bartosik, Dariusz

Publication type:

Article

Transcription inactivation through local refolding of the RNA polymerase structure.

Published in:

2009

By:

Belogurov, Georgiy A.;
Vassylyeva, Marina N.;
Sevostyanova, Anastasiya;
Appleman, James R.;
Xiang, Alan X.;
Lira, Ricardo;
Webber, Stephen E.;
Klyuyev, Sergiy;
Nudler, Evgeny;
Artsimovitch, Irina;
Vassylyev, Dmitry G.

Publication type:

Letter

Nano-Encapsulation and Conjugation Applied in the Development of Lipid Nanoparticles Delivering Nucleic Acid Materials to Enable Gene Therapies.

Published in:

Applied Nano, 2024, v. 5, n. 3, p. 143, doi. 10.3390/applnano5030011

By:

Dinh, Linh;
Mahon, Lanesa;
Yan, Bingfang

Publication type:

Article

Photon Counting CT and Radiomic Analysis Enables Differentiation of Tumors Based on Lymphocyte Burden.

Published in:

Tomography: A Journal for Imaging Research, 2022, v. 8, n. 2, p. 740, doi. 10.3390/tomography8020061

By:

Allphin, Alex J.;
Mowery, Yvonne M.;
Lafata, Kyle J.;
Clark, Darin P.;
Bassil, Alex M.;
Castillo, Rico;
Odhiambo, Diana;
Holbrook, Matthew D.;
Ghaghada, Ketan B.;
Badea, Cristian T.

Publication type:

Article

ATP2A1 regulates proliferation and migration in colorectal cancer and serves as a predictor of patient prognosis and immune infiltration.

Published in:

Journal of Hainan Medical University, 2024, v. 30, n. 10, p. 769, doi. 10.13210/j.cnki.jhmu.20240313.001

By:

DONG Rui;
ZHANG Fuxing;
WU Xinyue;
NI Zhikai;
WU Huazhang;
LIU Mulin

Publication type:

Article

The impact of habitat loss and population fragmentation on genomic erosion.

Published in:

Conservation Genetics, 2024, v. 25, n. 1, p. 49, doi. 10.1007/s10592-023-01548-9

By:

Pinto, Alessandro V.;
Hansson, Bengt;
Patramanis, Ioannis;
Morales, Hernán E.;
van Oosterhout, Cock

Publication type:

Article