Works matching DE "GENE silencing"

Results: 5000

Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy.

Published in:

OncoImmunology, 2014, v. 3, n. 7, p. N.PAG, doi. 10.4161/21624011.2014.945378

By:

Liechtenstein, Therese;
Perez-Janices, Noemi;
Blanco-Luquin, Idoia;
Goyvaerts, Cleo;
Schwarze, Julia;
Dufait, Ines;
Lanna, Alessio;
Ridder, Mark De;
Guerrero-Setas, David;
Breckpot, Karine;
Escors, David

Publication type:

Article

The effects of RNA interference mediated VEGF gene silencing on biological behavior of renal cell carcinoma and transplanted renal tumor in nude mice.

Published in:

Cancer Biomarkers, 2016, v. 16, n. 1, p. 1, doi. 10.3233/CBM-150535

By:

Qi Wang;
Shuai Wang;
Si-Qiao Sun;
Zhi-Hua Cheng;
Yang Zhang;
Guang Chen;
Meng Gu;
Hai-Jun Yao;
Zhong Wang;
Juan Zhou;
Yu-Bing Peng;
Ming-Xi Xu;
Ke Zhang;
Xi-Wei Sun

Publication type:

Article

siRNA-mediated knockdown of JUB expression suppresses the proliferation of glioblastoma cells.

Published in:

Cancer Biomarkers, 2015, v. 15, n. 4, p. 477, doi. 10.3233/CBM-150491

By:

Huoniu Ouyang;
Zhilin Guo;
Zhihua Cheng;
Yu Guo

Publication type:

Article

New transcriptomic insights in two RNAi wheat lines with the gliadins strongly down-regulated by two endosperm specific promoters.

Published in:

Crop Journal (2095-5421), 2022, v. 10, n. 1, p. 194, doi. 10.1016/j.cj.2021.04.009

By:

Marín-Sanz, Miriam;
Iehisa, Julio C. Masaru;
Barro, Francisco

Publication type:

Article

小贯小绿叶蝉卵黄原蛋白基因（EonuVg）克隆和功能研究及其对吡虫啉的响应

Published in:

Journal of Tea Science, 2025, v. 45, n. 3, p. 439

By:

潘铖;
夏露霞;
魏可欣;
王梦馨;
钮羽群;
韩宝瑜

Publication type:

Article

Suppression of ATP-dependent (S)-NAD(P)H-hydrate dehydratase expression inhibits adipocyte differentiation of 3T3-L1 preadipocytes by increasing excessive accumulation of NADHX Open Access.

Published in:

Journal of Biochemistry, 2025, v. 177, n. 6, p. 403, doi. 10.1093/jb/mvaf015

By:

Nakajima, Kazuki;
Takahashi, Kodai;
Tanaka, Masako;
Kawashima, Mina;
Machida, Koshi;
Nakao, Yoichi;
Takubo, Keiyo;
Goda, Nobuhito

Publication type:

Article

Role of LEAFLESS, an AP2/ERF family transcription factor, in the regulation of trichome specialized metabolism.

Published in:

New Phytologist, 2025, v. 247, n. 2, p. 774, doi. 10.1111/nph.70198

By:

Mandal, Sabyasachi;
Rezenom, Yohannes H.;
McKnight, Thomas D.

Publication type:

Article

Editing metacaspase (StMC7) gene enhances late blight resistance in Russet Burbank potato.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325702

By:

Poudel, Bikram;
Sathe, Atul;
Bede, Jacqueline C.;
Kushalappa, Ajjamada C.

Publication type:

Article

Efficacy of different light quality combinations in alleviating mottled yellowing in leaves of a new flue-cured tobacco line Hc400 seedlings.

Published in:

Tobacco Science & Technology, 2025, v. 58, n. 6, p. 19, doi. 10.16135/j.issn1002-0861.2024.0810

By:

LIANG Jingsong;
WANG Dong;
PENG Yu;
HE Xinxi;
XIONG Kunlong;
LI Junhui;
PENG Guangjue;
QIN Tian;
CHEN Weihao;
WANG Yuwen;
LI Juan

Publication type:

Article

BAIAP2L1在宫颈癌中表达的临床意义及其对宫颈癌细胞恶性表型的影响.

Published in:

Cancer Research on Prevention & Treatment, 2025, v. 52, n. 6, p. 481, doi. 10.3971/j.issn.1000-8578.2025.24.0951

By:

赵珏莹;
韩卓莹;
冯路路;
王晨龙;
张莉;
罗超;
王其龙

Publication type:

Article

Reply to: "c-di-GMP does not bind H-NS, nor inhibits H-NS binding DNA".

Published in:

2025

By:

Li, Shuyu;
Zhang, Lei

Publication type:

Letter

Spermidine synthase genes from mulberry play an important role in drought stress tolerance by altering antioxidant enzymes and osmotic regulation.

Published in:

Functional Plant Biology, 2025, v. 52, n. 6, p. 1, doi. 10.1071/FP24226

By:

Liu, Dan;
Lin, Qiang;
Qiu, Changyu;
Lu, Xiaomei;
He, Ningjia

Publication type:

Article

PARP-1 as a novel target in endocrine-resistant breast cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03441-4

By:

Zicarelli, Azzurra;
Talia, Marianna;
Lainé, Muriel;
Lappano, Rosamaria;
Maggiolini, Marcello;
Greene, Geoffrey L.

Publication type:

Article

Fungal effector genes involved in the suppression of chitin signaling as novel targets for the control of powdery mildew disease via a nontransgenic RNA interference approach.

Published in:

Pest Management Science, 2025, v. 81, n. 7, p. 3452, doi. 10.1002/ps.8660

By:

Bakhat, Nisrine;
Jiménez‐Sánchez, Alejandro;
Ruiz‐Jiménez, Laura;
Padilla‐Roji, Isabel;
Velasco, Leonardo;
Pérez‐García, Alejandro;
Fernández‐Ortuño, Dolores

Publication type:

Article

Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 4, p. 1, doi. 10.1007/s10928-025-09980-9

By:

Derbalah, Abdallah;
Stader, Felix;
Liu, Cong;
Zyla, Adriana;
Abdulla, Tariq;
Wu, Qier;
Jamei, Masoud;
Gardner, Ian;
Sepp, Armin

Publication type:

Article

Tobacco (Nicotiana tabacum) PSY peptides and their potential roles in seed germination, vegetative growth, and leaf senescence under osmotic stress.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1575308

By:

Deng, Zhichao;
Pan, Xiaolu;
Wu, Rongrong;
Yang, Yalun;
Liu, Tao;
Li, Wei;
Zhang, Zenglin;
Guo, Yongfeng

Publication type:

Article

Proteogenomic characterization reveals that lipid droplet formation promotes esophageal squamous cell cancer progression.

Published in:

Science Translational Medicine, 2025, v. 17, n. 802, p. 1, doi. 10.1126/scitranslmed.adt0214

By:

Qin, Zhaoyu;
Jiang, Dongxian;
Yu, Zihan;
Li, Lingling;
Xu, Wenhao;
Xu, Chen;
Song, Qi;
Sun, Xiaogang;
Li, Liangyuan;
Guo, Wenjia;
Pu, Yan;
Feng, Jinwen;
Liu, Yang;
Wang, Haixing;
Wang, Lan;
Qu, Yuanyuan;
He, Fuchu;
Qin, Jun;
Tan, Lijie;
Zhao, Jian-Yuan

Publication type:

Article

HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 6735, doi. 10.2147/JIR.S502616

By:

Zhou, Jilong;
Ding, Lihui;
Chen, Juan;
Chen, Chen;
Jiang, Ping;
Mei, Zongwei;
Jiang, Qing;
Hua, Xiaoliang

Publication type:

Article

Transmembrane Protease Serine 11B Modulates Lactate Transport Through SLC16A1 in Pancreatic Ductal Adenocarcinoma—A Functional Link to Phenotype Heterogeneity.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5398, doi. 10.3390/ijms26115398

By:

Baiskhanova, Dinara;
Menzel, Maike;
Geismann, Claudia;
Röcken, Christoph;
Beitz, Eric;
Sebens, Susanne;
Trauzold, Anna;
Schäfer, Heiner

Publication type:

Article

Proactive Resistance Management Studies Highlight the Role of Cytochrome P450 Genes in the Resistance of Tuta absoluta Against Tetraniliprole.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5180, doi. 10.3390/ijms26115180

By:

Ullah, Farman;
Ullah, Zeeshan;
Gul, Hina;
Li, Xiaowei;
Pan, Yuhan;
Zhang, Haixia;
Zhang, Zhijun;
Huang, Jun;
Emmanouil, Roditakis;
Guedes, Raul Narciso C.;
Desneux, Nicolas;
Lu, Yaobin

Publication type:

Article

Phenylalanine Ammonia-Lyase GhPAL9 Confers Resistance to Verticillium Wilt in Cotton.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 4983, doi. 10.3390/ijms26114983

By:

Li, Chuanzong;
Zhang, Guoshuai;
Cheng, Guanfu;
Wang, Qi

Publication type:

Article

An Efficient Rice Virus-Induced Gene Silencing System Mediated by Wheat Dwarf Virus.

Published in:

Applied Sciences (2076-3417), 2025, v. 15, n. 11, p. 5818, doi. 10.3390/app15115818

By:

Zhang, Yaqian;
Zhang, Xiaowan;
Yu, Lu;
Yan, Yijie;
Zhu, Senzhen;
Huang, Wanting;
Zhang, Xian;
Dang, Cong;
Xue, Dawei

Publication type:

Article

Unexpected proteins involved in the regulation of secondary metabolism in Myxococcus xanthus DK1622.

Published in:

Biotechnology & Applied Biochemistry, 2025, v. 72, n. 3, p. 577, doi. 10.1002/bab.2682

By:

Izzat, Selar;
Abdullah, Shahlaa M.;
Sabir, Mohammed N.;
Wei, Wen‐Ping;
Ye, Bang‐Ce;
Rachid, Shwan

Publication type:

Article

The relevance of RNA–DNA interactions as regulators of physiological functions.

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 7, p. 889, doi. 10.1007/s00424-025-03091-7

By:

Stötzel, Julia;
Warwick, Timothy;
Tirunagari, Praveenya;
Brandes, Ralf P.;
Leisegang, Matthias S.

Publication type:

Article

Correction: CircRNA‑PTPRA Knockdown Inhibits Atherosclerosis Progression by Repressing ox‑LDL‑Induced Endothelial Cell Injury via Sponging of miR‑671‑5p.

Published in:

2025

By:

Luo, Xueting;
Zhou, Xiaoli

Publication type:

Correction Notice

Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1606326

By:

Pang, Yanyu;
Tian, Lei;
Liu, Yufei;
Guo, Yifan;
Zhao, Jingwen;
Wang, Yutong;
Wang, Mengdi;
Zhao, Wenjing

Publication type:

Article

Identification and Experimental Validation of Prognostic Signature and Peroxisome-Related Key Genes in Clear Cell Renal Cell Carcinoma.

Published in:

International Journal of General Medicine, 2025, v. 18, p. 2687, doi. 10.2147/IJGM.S513102

By:

Fan, Congcong;
Li, Yifei;
Zhang, Weizhi;
Wang, Yining;
Li, Yanzhen;
Zheng, Jianjian;
Yu, Zhixian;
Guo, Yong

Publication type:

Article

Silencing of STX4 inhibits the proliferation, migration and invasion of ovarian cancer cells via EMT/MMP2/ CCND1 signaling pathway.

Published in:

Journal of Ovarian Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13048-025-01705-3

By:

Ye, Wenfeng;
Xue, Chunyan;
Chen, Linlin;
Chen, Xiangnan;
Zhang, Dachuan

Publication type:

Article

RNA-mediated gene silencing can reduce azole resistance, growth and pathogenicity in Pseudocercospora fijiensis.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325057

By:

Canacuán Melo, Flor Yuranny;
Suárez Anaya, Yohana Katerine;
Rey Valenzuela, Vicente Emilio;
Morales Osorio, Juan Gonzalo;
Arango Isaza, Rafael Eduardo

Publication type:

Article

Nested likelihood-ratio testing of the nonsynonymous:synonymous ratio suggests greater adaptation in the piRNA machinery of Drosophila melanogaster compared with Drosophila ananassae and Drosophila willistoni, two species with higher repeat content Open Access

Published in:

G3: Genes | Genomes | Genetics, 2025, v. 15, n. 4, p. 1, doi. 10.1093/g3journal/jkaf017

By:

Blumenstiel, Justin P;
Kingan, Sarah B;
Garrigan, Daniel;
Hill, Tom;
Vedanayagam, Jeffrey

Publication type:

Article

WNT3 promotes chemoresistance to oxaliplatin in oral squamous cell carcinoma via regulating ABCG2 expression.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01414-w

By:

Sun, Kairui;
Zhang, Xuyang;
Gan, Ruihuan;
Lin, Shuoqi;
Chen, Yu;
Zheng, Dali;
Lu, Youguang

Publication type:

Article

A plastid lipid-associated protein-encoding gene (GhPAP) that positively regulates fiber strength was identified via genetic mapping and transcriptomic analysis of a stable QTL on chromosome D06 of upland cotton.

Published in:

Theoretical & Applied Genetics, 2025, v. 138, n. 7, p. 1, doi. 10.1007/s00122-025-04922-y

By:

Zhang, Sujun;
Liu, Cunjing;
Tang, Liyuan;
Li, Xinghe;
Cai, Xiao;
Wang, Haitao;
Zhang, Jinfa;
Zhang, Jianhong

Publication type:

Article

Maternal loss of mouse Nlrp2 alters the transcriptome and DNA methylome in GV oocytes and impairs zygotic genome activation in embryos.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01889-x

By:

Anvar, Zahra;
Jochum, Michael D.;
Chakchouk, Imen;
Sharif, Momal;
Demond, Hannah;
To, Alvin K.;
Kraushaar, Daniel C.;
Wan, Ying-Wooi;
Mari, Michael C.;
Andrews, Simon;
Kelsey, Gavin;
Van den Veyver, Ignatia B.

Publication type:

Article

Case Report: A novel germline donor splicing site mutation of RB1 gene in a Chinese Tibetan pedigree with familial retinoblastoma.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1525035

By:

He, Guo-qian;
Zheng, Ying-chun;
Tan, Lin-jun;
Shen, Cheng-qi;
Gao, Ju;
Xiong, Fu;
Guo, Xia

Publication type:

Article

Ubinuclein 2 is essential for mouse development and functions in X chromosome inactivation.

Published in:

PLoS Genetics, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.pgen.1011711

By:

Monfort, Asun;
Di Minin, Giulio;
Sting, Sarah;
Dumeau, Charles Etienne;
Scambler, Peter;
Wutz, Anton

Publication type:

Article

Integrating Genetic Diversity and Agronomic Innovations for Climate-Resilient Maize Systems.

Published in:

Plants (2223-7747), 2025, v. 14, n. 10, p. 1552, doi. 10.3390/plants14101552

By:

Li, Xin;
Li, Yunlong;
Sun, Yan;
Li, Sinan;
Cai, Quan;
Li, Shujun;
Sun, Minghao;
Yu, Tao;
Meng, Xianglong;
Zhang, Jianguo

Publication type:

Article

Efficient Virus-Induced Gene Silencing (VIGS) Method for Discovery of Resistance Genes in Soybean.

Published in:

Plants (2223-7747), 2025, v. 14, n. 10, p. 1547, doi. 10.3390/plants14101547

By:

Deng, Kelin;
Lu, Zihua;
Yang, Hongli;
Chen, Shuilian;
Li, Chao;
Cao, Dong;
Wang, Hongwei;
Hao, Qingnan;
Chen, Haifeng;
Shan, Zhihui

Publication type:

Article

Screening and Identification of Drought-Tolerant Genes in Tomato (Solanum lycopersicum L.) Based on RNA-Seq Analysis.

Published in:

Plants (2223-7747), 2025, v. 14, n. 10, p. 1471, doi. 10.3390/plants14101471

By:

Ma, Yue;
Li, Yushan;
Wang, Fan;
Qing, Quan;
Deng, Chengzhu;
Wang, Hao;
Song, Yu

Publication type:

Article

Gene Silencing of Sarco/Endoplasmic Reticulum Ca 2 ⁺-ATPase and NADPH–Cytochrome P450 Reductase as a Novel Approach to Leptinotarsa decemlineata Management.

Published in:

Agronomy, 2025, v. 15, n. 5, p. 1151, doi. 10.3390/agronomy15051151

By:

Mendoza-Alatorre, Maribel;
Siqueiros-Cendón, Tania Samanta;
Torres-Castillo, Jorge Ariel;
Sinagawa-García, Sugey Ramona;
Iglesias-Figueroa, Blanca Flor;
Abraham-Juárez, María Jazmín;
González-Barriga, Carmen Daniela;
Rascón-Cruz, Quintín;
Siañez-Estrada, Luis Ignacio;
Espinoza-Sánchez, Edward Alexander

Publication type:

Article

Genome-Wide Analysis of Zm4CL Genes Identifies Zm4CL8 Regulating Drought and Salt Tolerance in Maize.

Published in:

Agronomy, 2025, v. 15, n. 5, p. 1100, doi. 10.3390/agronomy15051100

By:

Zhang, Ze;
Wang, Yanbin;
Li, Rong

Publication type:

Article

Targeting S1PR2 in Sepsis, One Fragmented Mitochondrion at a Time.

Published in:

2025

By:

He, Chao;
Larson-Casey, Jennifer L.

Publication type:

Editorial

MIKC-Type MADS-box Genes Regulate Phytohormone-Dependent Fruit Ripening in Tomatoes.

Published in:

Horticulturae, 2025, v. 11, n. 5, p. 487, doi. 10.3390/horticulturae11050487

By:

Li, Changxia;
Lu, Yushi;
Xu, Junrong;
Cui, Jing;
Liu, Yunzhi;
Yu, Wenjin

Publication type:

Article

Advancements in Gene Therapy for Non-Small Cell Lung Cancer: Current Approaches and Future Prospects.

Published in:

Genes, 2025, v. 16, n. 5, p. 569, doi. 10.3390/genes16050569

By:

Ziółkowska-Suchanek, Iwona;
Rozwadowska, Natalia

Publication type:

Article

Differential Effects of Sphingolipids on Cell Death and Antioxidant Defenses in Type 1 and Type 2 Endometrial Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4472, doi. 10.3390/ijms26104472

By:

Błachnio-Zabielska, Agnieszka U.;
Sadowska, Patrycja;
Chlabicz, Urszula;
Pogodzińska, Karolina;
Le Stunff, Hervé;
Laudański, Piotr;
Szamatowicz, Jacek;
Kuźmicki, Mariusz

Publication type:

Article

Reduction in Acute Bee Paralysis Virus Infection and Mortality in Honey Bees (Apis mellifera) by RNA Interference Technology.

Published in:

Insects (2075-4450), 2025, v. 16, n. 5, p. 453, doi. 10.3390/insects16050453

By:

Ferrufino, Cecilia;
Scannapieco, Alejandra;
Russo, Romina María;
Gonzalez, Fernanda Noemí;
Salvador, Ricardo;
Dus Santos, María José

Publication type:

Article

Decoding the Function of FGFBP1 in Sheep Adipocyte Proliferation and Differentiation.

Published in:

Animals (2076-2615), 2025, v. 15, n. 10, p. 1456, doi. 10.3390/ani15101456

By:

Tian, Liming;
He, Zhaohua;
Wang, Guan;
Zhang, Shuhong;
Di, Tenggang;
Chang, Menghan;
Han, Wei;
Gao, Jingyi;
Li, Meng;
Wang, Ziyi;
Zhang, Huan;
Li, Shaobin;
Yang, Guangli

Publication type:

Article

Regulation of microRNA-mediated gene silencing by microRNA precursors.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 9, p. 825, doi. 10.1038/nsmb.2862

By:

Roy-Chaudhuri, Biswajoy;
Valdmanis, Paul N;
Zhang, Yue;
Wang, Qing;
Luo, Qing-Jun;
Kay, Mark A

Publication type:

Article

Revolution in the Polycomb hierarchy.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 7, p. 573, doi. 10.1038/nsmb.2848

By:

Comet, Itys;
Helin, Kristian

Publication type:

Article

Activating silent Argonautes.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 769, doi. 10.1038/nsmb.2620

By:

Kidwell, Mary Anne;
Doudna, Jennifer A

Publication type:

Article

Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 735, doi. 10.1038/nsmb.2572

By:

Fabian, Marc R;
Frank, Filipp;
Rouya, Christopher;
Siddiqui, Nadeem;
Lai, Wi S;
Karetnikov, Alexey;
Blackshear, Perry J;
Nagar, Bhushan;
Sonenberg, Nahum

Publication type:

Article