Works matching DE "GASTRIC inhibitory polypeptide"

Results: 424

Acute Inhibition of Adipose Triglyceride Lipase by NG497 Dysregulates Insulin and Glucagon Secretion From Human Islets Open Access.

Published in:

Endocrinology, 2025, v. 166, n. 7, p. 1, doi. 10.1210/endocr/bqaf090

By:

Kim, Lucy B;
Liu, Siming;
Richtsmeier, Syreine;
Górniak, Michał;
Vikram, Anamika;
Imai, Yumi

Publication type:

Article

Curcumin alleviates visceral adiposity via inhibiting GIP release from hypoxic intestinal damage in MASH rats.

Published in:

NPJ Science of Food, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41538-025-00466-z

By:

Liao, Yingyi;
Xie, Xingyu;
Lin, Zixin;
Huang, Ning;
Wei, Guilan;
Wu, Jiazhen;
Li, Yucui;
Chen, Jiannan;
Su, Ziren;
Yu, Xiuting;
Chen, Liping;
Liu, Yuhong

Publication type:

Article

Incretin‐based therapies for the management of cardiometabolic disease in the clinic: Past, present, and future.

Published in:

2025

By:

Psaltis, James P.;
Marathe, Jessica A.;
Nguyen, Mau T.;
Le, Richard;
Bursill, Christina A.;
Marathe, Chinmay S.;
Nelson, Adam J.;
Psaltis, Peter J.

Publication type:

Literature Review

Molecular Pharmacology of the Incretin Receptors.

Published in:

2016

By:

Al-Sabah, Suleiman

Publication type:

journal article

Viking Therapeutics Advances 3 Potential Obesity Treatments Based on Promising 2024 Clinical Trial Results.

Published in:

Patient Care (Online), 2025, p. 7

By:

Halsey, Grace

Publication type:

Article

Roche Says Investigational Once-Weekly "Twincretin" Shows Promise in Adults with Obesity in Early Stage Clinical Trial.

Published in:

Patient Care (Online), 2024, p. 1

By:

Halsey, Grace

Publication type:

Article

Adverse Events Related to Tirzepatide.

Published in:

Journal of the Endocrine Society, 2023, v. 7, n. 4, p. 1, doi. 10.1210/jendso/bvad016

By:

Mishra, Rahul;
Raj, Rishi;
Elshimy, Ghada;
Zapata, Isain;
Kannan, Lakshmi;
Majety, Priyanka;
Edem, Dinesh;
Correa, Ricardo

Publication type:

Article

Glucose-Dependent Insulinotropic Polypeptide (GIP) Reduces Bone Resorption in Patients With Type 2 Diabetes.

Published in:

Journal of the Endocrine Society, 2020, v. 4, n. 9, p. 1, doi. 10.1210/jendso/bvaa097

By:

Christensen, Mikkel B;
Lund, Asger B;
Jørgensen, Niklas R;
Holst, Jens J;
Vilsbøll, Tina;
Knop, Filip K

Publication type:

Article

Serum Secretogranin III Concentrations Were Increased in Subjects with Metabolic Syndrome and Independently Associated with Fasting Plasma Glucose Levels.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 9, p. 1436, doi. 10.3390/jcm8091436

By:

Lin, Chun-Chung;
Cheng, Kai-Pi;
Hung, Hao-Chang;
Li, Chung-Hao;
Lin, Ching-Han;
Chang, Chih-Jen;
Hu, Che-Yuan;
Wu, Hung-Tsung;
Ou, Horng-Yih

Publication type:

Article

Effects of gastric inhibitory polypeptide, glucagon-like peptide-1 and glucagon-like peptide-1 receptor agonists on Bone Cell Metabolism.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 1, p. 25, doi. 10.1111/bcpt.12850

By:

Hansen, Morten S. S.;
Tencerova, Michaela;
Frølich, Jacob;
Kassem, Moustapha;
Frost, Morten

Publication type:

Article

Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2017, v. 121, n. 4, p. 290, doi. 10.1111/bcpt.12792

By:

Røge, Rikke M.;
Bagger, Jonatan I.;
Alskär, Oskar;
Kristensen, Niels R.;
Klim, Søren;
Holst, Jens J.;
Ingwersen, Steen H.;
Karlsson, Mats O.;
Knop, Filip K.;
Vilsbøll, Tina;
Kjellsson, Maria C.

Publication type:

Article

TAK-875 Mitigates β-Cell Lipotoxicity-Induced Metaflammation Damage through Inhibiting the TLR4-NF-κB Pathway.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/5487962

By:

Chen, Xide;
Yan, Yuanli;
Weng, Zhiyan;
Chen, Chao;
Lv, Miaoru;
Lin, Qingwen;
Du, Qiuxia;
Shen, Ximei;
Yang, Liyong

Publication type:

Article

Predictors of Effectiveness of Glucagon-Like Peptide-1 Receptor Agonist Therapy in Patients with Type 2 Diabetes and Obesity.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/1365162

By:

Babenko, Alina Yu.;
Savitskaya, Daria A.;
Kononova, Yulia A.;
Trofimova, Aleksandra Yu.;
Simanenkova, Anna V.;
Vasilyeva, Elena Yu.;
Shlyakhto, Evgeny V.

Publication type:

Article

Glucagon‐like peptide‐1 receptor is expressed in human and rodent testis.

Published in:

Andrology, 2020, v. 8, n. 6, p. 1935, doi. 10.1111/andr.12871

By:

Caltabiano, Rosario;
Condorelli, Daniele;
Panza, Salvatore;
Boitani, Carla;
Musso, Nicolò;
Ježek, Davor;
Memeo, Lorenzo;
Colarossi, Lorenzo;
Rago, Vittoria;
Mularoni, Valentina;
Spadola, Saveria;
Castiglione, Roberto;
Santoro, Marta;
Aquila, Saveria;
D'Agata, Rosario

Publication type:

Article

Helicobacter pylori enhances HLA‐C expression in the human gastric adenocarcinoma cells AGS and can protect them from the cytotoxicity of natural killer cells.

Published in:

Helicobacter, 2024, v. 29, n. 2, p. 1, doi. 10.1111/hel.13069

By:

Apoorva, Etikala;
Jacob, Rini;
Rao, Desirazu N.;
Kumar, Santosh

Publication type:

Article

Constitutive programmed death ligand 1 expression protects gastric G‐cells from Helicobacter pylori–induced inflammation.

Published in:

Helicobacter, 2022, v. 27, n. 5, p. 1, doi. 10.1111/hel.12917

By:

Mommersteeg, Michiel C.;
Yu, Bing Ting;
van den Bosch, Thierry P. P.;
von der Thüsen, Johan H.;
Kuipers, Ernst J.;
Doukas, Michael;
Spaander, Manon C. W.;
Peppelenbosch, Maikel P.;
Fuhler, Gwenny M.

Publication type:

Article

Glucose-dependent insulinotropic polypeptide stimulates post-absorptive lipid secretion in the intestine.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1549392

By:

Wang, Rong;
Khan, Muhammad Saad Abdullah;
Mukherjee, Kundanika;
Ghanem, Murooj;
Xiao, Changting

Publication type:

Article

Editorial: Reviews and Novel Clinical Perspectives on Semaglutide: A GLP-1 Receptor Agonist With Both Injectable and Oral Formulations.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.760153

By:

Meier, Juris J.;
Gallwitz, Baptist;
Giorgino, Francesco

Publication type:

Article

Variation in the Evolution and Sequences of Proglucagon and the Receptors for Proglucagon-Derived Peptides in Mammals.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.700066

By:

Irwin, David M.

Publication type:

Article

Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.681116

By:

Jonsson, Isabella;
Bojsen-Møller, Kirstine N.;
Kristiansen, Viggo B.;
Veedfald, Simon;
Wewer Albrechtsen, Nicolai J.;
Clausen, Trine R.;
Kuhre, Rune E.;
Rehfeld, Jens F.;
Holst, Jens J.;
Madsbad, Sten;
Svane, Maria S.

Publication type:

Article

Pathological Hyperinsulinemia and Hyperglycemia in the Impaired Glucose Tolerance Stage Mediate Endothelial Dysfunction Through miR-21, PTEN/AKT/eNOS, and MARK/ET-1 Pathways.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.644159

By:

Liu, Ran;
Guan, Shilin;
Gao, Zhongai;
Wang, Jingyu;
Xu, Jie;
Hao, Zhaohu;
Zhang, Yi;
Yang, Shaohua;
Guo, Zhenhong;
Yang, Juhong;
Shao, Hailin;
Chang, Baocheng

Publication type:

Article

Detour Ahead: Incretin Hormone Signaling Alters Its Intracellular Path as β-Cell Failure Progresses During Diabetes.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.665345

By:

Hussain, Mehboob A.;
Laimon-Thomson, Erinn;
Mustafa, Syed M.;
Deck, Alexander;
Song, Banya

Publication type:

Article

Mathematical Model of Glucagon Kinetics for the Assessment of Insulin-Mediated Glucagon Inhibition During an Oral Glucose Tolerance Test.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.611147

By:

Morettini, Micaela;
Burattini, Laura;
Göbl, Christian;
Pacini, Giovanni;
Ahrén, Bo;
Tura, Andrea

Publication type:

Article

Model-Based Assessment of C-Peptide Secretion and Kinetics in Post Gastric Bypass Individuals Experiencing Postprandial Hyperinsulinemic Hypoglycemia.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.611253

By:

Schiavon, Michele;
Herzig, David;
Hepprich, Matthias;
Donath, Marc Y.;
Bally, Lia;
Dalla Man, Chiara

Publication type:

Article

Immune System Effects of Insulin-Like Peptide 5 in a Mouse Model.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.610672

By:

Vahkal, Brett;
Yegorov, Sergey;
Onyilagha, Chukwunonso;
Donner, Jacqueline;
Reddick, Dean;
Shrivastav, Anuraag;
Uzonna, Jude;
Good, Sara V.

Publication type:

Article

ARHGAP21 Acts as an Inhibitor of the Glucose-Stimulated Insulin Secretion Process.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.599165

By:

Ferreira, Sandra M.;
Costa-Júnior, José M.;
Kurauti, Mirian A.;
Leite, Nayara C.;
Ortis, Fernanda;
Rezende, Luiz F.;
Barbosa, Helena C.;
Boschero, Antonio C.;
Santos, Gustavo J.

Publication type:

Article

GIP_HUMAN [22–51] Peptide Encoded by the Glucose-Dependent Insulinotropic Polypeptide (GIP) Gene Suppresses Insulin Expression and Secretion in INS-1E Cells and Rat Pancreatic Islets.

Published in:

Genes, 2023, v. 14, n. 10, p. 1910, doi. 10.3390/genes14101910

By:

Pusch, Emily;
Krążek, Małgorzata;
Wojciechowicz, Tatiana;
Sassek, Maciej;
Kołodziejski, Paweł A.;
Strowski, Mathias Z.;
Nowak, Krzysztof W.;
Skrzypski, Marek

Publication type:

Article

Hippocampal Changes Elicited by Metabolic and Inflammatory Stressors following Prenatal Maternal Infection.

Published in:

Genes, 2023, v. 14, n. 1, p. 77, doi. 10.3390/genes14010077

By:

Rodriguez-Zas, Sandra L.;
Southey, Bruce R.;
Rymut, Haley E.;
Rund, Laurie A.;
Johnson, Rodney W.

Publication type:

Article

Dominant-negative inhibition of glucose-dependent insulinotropic polypeptide impairs function of β cells in transgenic pigs.

Published in:

2015

By:

JunLin Cheng;
Ying Wang;
Zhengwei Zhang;
Yong Jin;
QianKun Li;
RongGen Want;
Yan Wang;
XiaoKang Li;
Qiang Xiong;
ManLing Zhang;
RongFeng Li;
YiFan Dai

Publication type:

Letter to the Editor

Medical Update.

Published in:: American Journal on Addictions, 2024, v. 33, n. 2, p. 248, doi. 10.1111/ajad.13528
Publication type:: Article

Tirzepatide (Zepbound) for the Treatment of Obesity.

Published in:

American Family Physician, 2024, v. 110, n. 2, p. 199

By:

Coppenrath, Valerie;
Mazyck, Beth

Publication type:

Article

Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest.

Published in:

Journal of Transplantation, 2012, p. 1, doi. 10.1155/2012/230870

By:

Mellado-Gil, Jose Manuel;
Cobo-Vuilleumier, Nadia;
Gauthier, Benoit R.

Publication type:

Article

EBM BLS: Adding tirzepatide to long-acting insulin is superior to adding mealtime insulin for type 2 diabetes mellitus.

Published in:

JGIM: Journal of General Internal Medicine, 2024, v. 39, n. 14, p. 2878, doi. 10.1007/s11606-024-08901-9

By:

Fuest, Stephen;
Ganipisetti, Venu;
Cunningham, John M.

Publication type:

Article

Editorial for the Special Issue "Advances in Clinical Diabetes, Obesity, and Metabolic Diseases".

Published in:

2025

By:

Ohshiro, Yuzuru;
Yagi, Kunimasa;
Maeno, Yasuhiro

Publication type:

Editorial

Impact of Dietary Fiber on Inflammation in Humans.

Published in:

2025

By:

Kabisch, Stefan;
Hajir, Jasmin;
Sukhobaevskaia, Varvara;
Weickert, Martin O.;
Pfeiffer, Andreas F. H.

Publication type:

Literature Review

Differences in GIP Receptor Expression by Feeding Status in the Mouse Brain.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 3, p. 1142, doi. 10.3390/ijms26031142

By:

Song, Do Kyeong;
Jung, Narae;
Sung, Yeon-Ah;
Hong, Young Sun;
Lee, Hyejin

Publication type:

Article

Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats.

Published in:

Cardiovascular Diabetology, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12933-015-0194-3

By:

Xiaoyan Zhou;
Chin-hu Huang;
Lao, Julie;
Pocai, Alessandro;
Forrest, Gail;
Price, Olga;
Roy, Sophie;
Kelley, David E.;
Sullivan, Kathleen A.;
Forrest, Michael J.

Publication type:

Article

Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets.

Published in:

Biological Procedures Online, 2020, v. 22, n. 1, p. 1, doi. 10.1186/s12575-019-0116-y

By:

Röthe, Juliane;
Kraft, Robert;
Schöneberg, Torsten;
Thor, Doreen

Publication type:

Article

Synthesis and antitumor activity of sacroflavonoside.

Published in:

Natural Product Research, 2021, v. 35, n. 8, p. 1292, doi. 10.1080/14786419.2019.1645660

By:

Wang, Qinghu;
Xin, Ying;
Pa, Biligetu;
He, Xiang;
Bao, Wenqiang

Publication type:

Article

Inhibitory effects and molecular mechanisms of pentagalloyl glucose in combination with 5-FU on aggressive phenotypes of HepG2 cells.

Published in:

Natural Product Research, 2021, v. 35, n. 5, p. 815, doi. 10.1080/14786419.2019.1598991

By:

Ding, Xiao-Qing;
Zhao, Shuang;
Wang, Jian-Ye;
Zheng, Hua-chuan;
Ma, Chao-Mei

Publication type:

Article

Bacterial supernatants elevate glucose-dependent insulin secretion in rat pancreatic INS-1 line and islet β-cells via PI3K/AKT signaling.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 452, n. 1/2, p. 17, doi. 10.1007/s11010-018-3408-7

By:

Ramenzoni, Liza L.;
Zuellig, Richard A.;
Hussain, Abbas;
Lehmann, Roger;
Heumann, Christian;
Attin, Thomas;
Schmidlin, Patrick R.

Publication type:

Article

Dipeptidyl Peptidase-4 Inhibitors: A Systematic Review of Structure-Activity Relationship Studies.

Published in:

IJ Pharmaceutical Research (IJPR), 2024, v. 23, n. 1, p. 1, doi. 10.5812/ijpr-151581

By:

Bayanati, Maryam;
Rabbani, Mohammad Ismail Mahboubi;
Kabiri, Shirin Sirous;
Mir, Bahareh;
Rezaee, Elham;
Tabatabai, Sayyed Abbas

Publication type:

Article

Effect of corn processing on growth performance, carcass characteristics, and plasma glucose-dependent insulinotropic polypeptide and metabolite concentrations in feedlot cattle.

Published in:

Translational Animal Science, 2020, v. 4, n. 2, p. 1, doi. 10.1093/tas/txaa009

By:

Freitas, Tiago B;
Felix, Tara L;
Shriver, Wayne;
Fluharty, Francis L;
Relling, Alejandro E

Publication type:

Article

Newer, Older, and Alternative Agents for the Eradication of Helicobacter pylori Infection: A Narrative Review.

Published in:

Antibiotics (2079-6382), 2023, v. 12, n. 6, p. 946, doi. 10.3390/antibiotics12060946

By:

Buzás, György Miklós;
Birinyi, Péter

Publication type:

Article

A novel integrated QSP model of in vivo human glucose regulation to support the development of a glucagon/GLP‐1 dual agonist.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 3, p. 302, doi. 10.1002/psp4.12752

By:

Bosch, Rolien;
Petrone, Marcella;
Arends, Rosalin;
Vicini, Paolo;
Sijbrands, Eric J. G.;
Hoefman, Sven;
Snelder, Nelleke

Publication type:

Article

A Physiologically‐Based Quantitative Systems Pharmacology Model of the Incretin Hormones GLP‐1 and GIP and the DPP4 Inhibitor Sitagliptin.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 6, p. 353, doi. 10.1002/psp4.12520

By:

Balazki, Pavel;
Schaller, Stephan;
Eissing, Thomas;
Lehr, Thorsten

Publication type:

Article

Tirzepatide (Mounjaro)-induced acute pancreatitis and ketoacidosis in an adult nondiabetic patient.

Published in:

2025

By:

Sallam, Asma Ali;
Alenezi, Bdoor Attaulla;
Albugami, Muneerah M.

Publication type:

Case Study

Improving glycemic control: transitioning from dulaglutide to tirzepatide in patients with type 2 diabetes undergoing hemodialysis.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1362242

By:

Emiko Otsuka;
Mineaki Kitamura;
Satoshi Funakoshi;
Hiroshi Mukae;
Tomoya Nishino

Publication type:

Article

Early combination therapy with SGLT2i and GLP‐1 RA or dual GIP/GLP‐1 RA in type 2 diabetes.

Published in:

2025

By:

Vale, Catarina;
Lourenço, Inês Mariana;
Jordan, Gabriela;
Golovaty, Ilya;
Torres, Hugo;
Moin, Tannaz;
Buysschaert, Martin;
Neves, João Sérgio;
Bergman, Michael

Publication type:

Literature Review

Hepatobiliary effects and safety of tirzepatide: A systematic review and meta‐analysis.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 12, p. 6074, doi. 10.1111/dom.15948

By:

Kamrul‐Hasan, A. B. M.;
Dutta, Deep;
Nagendra, Lakshmi;
Kuchay, Mohammad Shafi;
Islam, Md. Saiful;
Pappachan, Joseph M.

Publication type:

Article