Works matching DE "G protein-coupled receptor kinases"

Results: 170

Role of amino acid residues surrounding the phosphorylation site in peptide substrates of G protein-coupled receptor kinase 2 (GRK2).

Published in:

Amino Acids, 2016, v. 48, n. 12, p. 2875, doi. 10.1007/s00726-016-2345-6

By:

Asai, Daisuke;
Murata, Masaharu;
Toita, Riki;
Kawano, Takahito;
Nakashima, Hideki;
Kang, Jeong-Hun

Publication type:

Article

Monitoring of phosphorylated peptides by radioactive assay and matrix-assisted laser desorption-ionization time-of-flight mass spectrometry.

Published in:

Amino Acids, 2015, v. 47, n. 11, p. 2377, doi. 10.1007/s00726-015-2025-y

By:

Kang, Jeong-Hun;
Asai, Daisuke;
Toita, Riki;
Kawano, Takahito;
Murata, Masaharu

Publication type:

Article

Activation of Lysophosphatidic Acid Receptor Is Coupled to Enhancement of Ca2+-Activated Potassium Channel Currents.

Published in:

Korean Journal of Physiology & Pharmacology, 2013, v. 17, n. 3, p. 223, doi. 10.4196/kjpp.2013.17.3.223

By:

Sun-Hye Choi;
Byung-Hwan Lee;
Hyeon-Joong Kim;
Sung-Hee Hwang;
Sang-Mok Lee;
Seung-Yeol Nah

Publication type:

Article

Overexpression of GRK6 associates with the progression and prognosis of colorectal carcinoma.

Published in:

Oncology Letters, 2018, v. 15, n. 4, p. 5879, doi. 10.3892/ol.2018.8030

By:

Tao, Ran;
Li, Qiang;
Gao, Xiaofei;
Ma, Lilin

Publication type:

Article

Evaluation of the Role of G Protein-Coupled Receptor Kinase 3 in Desensitization of Mouse Odorant Receptors in a Mammalian Cell Line and in Olfactory Sensory Neurons.

Published in:

Chemical Senses, 2014, v. 39, n. 9, p. 771, doi. 10.1093/chemse/bju050

By:

Kato, Aya;
Reisert, Johannes;
Ihara, Sayoko;
Yoshikawa, Keiichi;
Touhara, Kazushige

Publication type:

Article

An Odorant Derivative as an Antagonist for an Olfactory Receptor.

Published in:

Chemical Senses, 2004, v. 29, n. 9, p. 815, doi. 10.1093/chemse/bjh247

By:

Oka, Yuki;
Nakamura, Akio;
Watanabe, Hidenori;
Touhara, Kazushige

Publication type:

Article

Editorial: G Protein-Coupled Receptor Kinases (GRKs) and β-Arrestins: New Insights Into Disease Regulators.

Published in:

2020

By:

Hattori, Yuichi;
Michel, Martin C.

Publication type:

Editorial

GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.652628

By:

Lee, Seunghun P.;
Qi, Jenson;
Xu, Guozhang;
Rankin, Matthew M.;
Littrell, James;
Xu, June Zhi;
Bakaj, Ivona;
Pocai, Alessandro

Publication type:

Article

GRK2 Suppresses Hepatocellular Carcinoma Metastasis and Invasion Through Down-Regulation of Prostaglandin E Receptor 2.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 9559, doi. 10.2147/OTT.S266641

By:

Li, Nan;
Wu, Jing-Jing;
Chen, Ting-Ting;
Li, Xiu-Qin;
Du, Jia-Jia;
Shan, Shan;
Wei, Wei;
Sun, Wu-Yi

Publication type:

Article

Six Commercially Available Angiotensin II AT Receptor Antibodies are Non-specific.

Published in:

Cellular & Molecular Neurobiology, 2012, v. 32, n. 8, p. 1353, doi. 10.1007/s10571-012-9862-y

By:

Benicky, Julius;
Hafko, Roman;
Sanchez-Lemus, Enrique;
Aguilera, Greti;
Saavedra, Juan

Publication type:

Article

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell.

Published in:

Nature Medicine, 2012, v. 18, n. 4, p. 618, doi. 10.1038/nm.2695

By:

Yui, Shiro;
Nakamura, Tetsuya;
Sato, Toshiro;
Nemoto, Yasuhiro;
Mizutani, Tomohiro;
Zheng, Xiu;
Ichinose, Shizuko;
Nagaishi, Takashi;
Okamoto, Ryuichi;
Tsuchiya, Kiichiro;
Clevers, Hans;
Watanabe, Mamoru

Publication type:

Article

Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3.

Published in:

Nature Genetics, 2013, v. 45, n. 1, p. 93, doi. 10.1038/ng.2492

By:

Nesbit, M Andrew;
Hannan, Fadil M;
Howles, Sarah A;
Reed, Anita A C;
Cranston, Treena;
Thakker, Clare E;
Gregory, Lorna;
Rimmer, Andrew J;
Rust, Nigel;
Graham, Una;
Morrison, Patrick J;
Hunter, Steven J;
Whyte, Michael P;
McVean, Gil;
Buck, David;
Thakker, Rajesh V

Publication type:

Article

Channeling Relaxation through Multiple Means: TMEM16A Antagonism for Asthma.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 72, n. 5, p. 466, doi. 10.1165/rcmb.2024-0521ED

By:

Jannu, Arun K.;
Penn, Raymond B.

Publication type:

Article

Opsin 3-GαS Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 1, p. 59, doi. 10.1165/rcmb.2020-0392OC

By:

Wu, Amy D.;
Dan, William;
Yi Zhang;
Vemaraju, Shruti;
Upton, Brian A.;
Lang, Richard A.;
Buhr, Ethan D.;
Berkowitz, Dan E.;
Gallos, George;
Emala, Charles W.;
Yim, Peter D.

Publication type:

Article

GRK2 and Mitochondrial Dynamics in Cardiovascular Health and Disease.

Published in:

2025

By:

Gatto, Cristina;
Rusciano, Maria Rosaria;
Visco, Valeria;
Ciccarelli, Michele

Publication type:

Literature Review

Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels.

Published in:

Cardiovascular Diabetology, 2016, v. 15, p. 1, doi. 10.1186/s12933-016-0474-6

By:

Lucas, Elisa;
Vila-Bedmar, Rocio;
Arcones, Alba C.;
Cruces-Sande, Marta;
Cachofeiro, Victoria;
Mayor Jr., Federico;
Murga, Cristina

Publication type:

Article

A KSHV microRNA Directly Targets G Protein-Coupled Receptor Kinase 2 to Promote the Migration and Invasion of Endothelial Cells by Inducing CXCR2 and Activating AKT Signaling.

Published in:

PLoS Pathogens, 2015, v. 11, n. 9, p. 1, doi. 10.1371/journal.ppat.1005171

By:

Hu, Minmin;
Wang, Cong;
Li, Wan;
Lu, Weiping;
Bai, Zhiqiang;
Qin, Di;
Yan, Qin;
Zhu, Jianzhong;
Krueger, Brian J.;
Renne, Rolf;
Gao, Shou-Jiang;
Lu, Chun

Publication type:

Article

G protein-coupled receptor kinase 2 modifies the cellular reaction to cisplatin through interactions with NADPH oxidase 4.

Published in:

Molecular & Cellular Biochemistry, 2021, v. 476, n. 3, p. 1505, doi. 10.1007/s11010-020-03969-3

By:

Ammon, Jane C.;
Valls, Danielle;
Eldemerdash, Mohamed;
Patel, Jigisha R.;
Tran, Philip D.;
Feng, Lifeng;
Gi, Michael;
Gonzalez, Trang T.;
Phan, Chuc;
Zendejas, Ashley E.;
So, Christopher H.

Publication type:

Article

G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 461, n. 1/2, p. 103, doi. 10.1007/s11010-019-03594-9

By:

Lagman, Joann;
Sayegh, Paula;
Lee, Christina S.;
Sulon, Sarah M.;
Jacinto, Alec Z.;
Sok, Vanessa;
Peng, Natalie;
Alp, Deniz;
Benovic, Jeffrey L.;
So, Christopher H.

Publication type:

Article

Phosphorylation of GIT1 tyrosine 321 is required for association with FAK at focal adhesions and for PDGF-activated migration of osteoblasts.

Published in:

Molecular & Cellular Biochemistry, 2012, v. 365, n. 1/2, p. 109, doi. 10.1007/s11010-012-1249-3

By:

Ren, Yongxin;
Yu, Lipeng;
Fan, Jin;
Rui, Ze;
Hua, Zhengzhe;
Zhang, Zitao;
Zhang, Ning;
Yin, Guoyong

Publication type:

Article

Alpha2-adrenoceptors in adrenomedullary chromaffin cells: functional role and pathophysiological implications.

Published in:

Pflügers Archiv: European Journal of Physiology, 2018, v. 470, n. 1, p. 61, doi. 10.1007/s00424-017-2059-y

By:

Artalejo, Antonio R.;
Olivos-Oré, Luis Alcides

Publication type:

Article

New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?

Published in:

Pflügers Archiv: European Journal of Physiology, 2013, v. 465, n. 12, p. 1671, doi. 10.1007/s00424-013-1284-2

By:

Liu, Tong;
Ji, Ru-Rong

Publication type:

Article

Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-?1 signaling and induction of Foxp3+ regulatory T cells.

Published in:

Nature Immunology, 2013, v. 14, n. 2, p. 162, doi. 10.1038/ni.2499

By:

Strainic, Michael G;
Shevach, Ethan M;
An, Fengqi;
Lin, Feng;
Medof, M Edward

Publication type:

Article

Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases.

Published in:

Nature Immunology, 2012, v. 13, n. 5, p. 457, doi. 10.1038/ni.2258

By:

Liu, Xiaowen;
Ma, Bo;
Malik, Asrar B;
Tang, Haiyang;
Yang, Tao;
Sun, Bo;
Wang, Gang;
Minshall, Richard D;
Li, Yan;
Zhao, Yong;
Ye, Richard D;
Xu, Jingsong

Publication type:

Article

Unknown Mechanisms Regulating the GPCR Signal Cascade in Vertebrate Photoreceptors.

Published in:

Neuroscience & Behavioral Physiology, 2012, v. 42, n. 2, p. 180, doi. 10.1007/s11055-011-9551-1

By:

Govardovskii, V.;
Firsov, M.

Publication type:

Article

G protein‐coupled receptor kinases are associated with Alzheimer's disease pathology.

Published in:

Neuropathology & Applied Neurobiology, 2021, v. 47, n. 7, p. 942, doi. 10.1111/nan.12742

By:

Guimarães, Thais Rafael;
Swanson, Eric;
Kofler, Julia;
Thathiah, Amantha

Publication type:

Article

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs.

Published in:

Carcinogenesis, 2013, v. 34, n. 5, p. 1150, doi. 10.1093/carcin/bgt020

By:

Al-Kharusi, Manal R.A.;
Smartt, Helena J.M.;
Greenhough, Alexander;
Collard, Tracey J.;
Emery, Elizabeth D.;
Williams, Ann C.;
Paraskeva, Chris

Publication type:

Article

Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization.

Published in:

Science Signaling, 2018, v. 11, n. 539, p. 1, doi. 10.1126/scisignal.aas9609

By:

Miess, Elke;
Gondin, Arisbel B.;
Yousuf, Arsalan;
Steinborn, Ralph;
Mösslein, Nadja;
Yang, Yunshi;
Göldner, Martin;
Ruland, Julia G.;
Bünemann, Moritz;
Krasel, Cornelius;
Christie, MacDonald J.;
Halls, Michelle L.;
Schulz, Stefan;
Canals, Meritxell

Publication type:

Article

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.

Published in:

Science Signaling, 2018, v. 11, n. 516, p. 1, doi. 10.1126/scisignal.aao5749

By:

Pusapati, Ganesh V.;
Kong, Jennifer H.;
Patel, Bhaven B.;
Gouti, Mina;
Sagner, Andreas;
Sircar, Ria;
Luchetti, Giovanni;
Ingham, Philip W.;
Briscoe, James;
Rohatgi, Rajat

Publication type:

Article

Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases.

Published in:

Science Signaling, 2018, v. 11, n. 516, p. 1, doi. 10.1126/scisignal.aan8660

By:

Li, Shuang;
Li, Shuangxi;
Wang, Bing;
Jiang, Jin

Publication type:

Article

Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2.

Published in:

Science Signaling, 2015, v. 8, n. 386, p. 1, doi. 10.1126/scisignal.aaa4374

By:

Vila-Bedmar, Rocio;
Cruces-Sande, Marta;
Lucas, Elisa;
Willemen, Hanneke L. D. M.;
Heijnen, Cobi J.;
Kavelaars, Annemieke;
Mayor Jr., Federico;
Murga, Cristina

Publication type:

Article

Modulation of Voltage-Gated Ca2+ Channels by G Protein-Coupled Receptors in Celiac-Mesenteric Ganglion Neurons of Septic Rats.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125566

By:

Farrag, Mohamed;
Laufenberg, Lacee J.;
Steiner, Jennifer L.;
Weller, Gregory E.;
Lang, Charles H.;
Ruiz-Velasco, Victor

Publication type:

Article

Functionally Selective Signaling for Morphine and Fentanyl Antinociception and Tolerance Mediated by the Rat Periaqueductal Gray.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114269

By:

Morgan, Michael M.;
Reid, Rachel A.;
Saville, Kimber A.

Publication type:

Article

GRK5 Intronic (CA)n Polymorphisms Associated with Type 2 Diabetes in Chinese Hainan Island.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090597

By:

Xia, Zhenfang;
Yang, Tubao;
Wang, Zhuansuo;
Dong, Jianping;
Liang, Chunyan

Publication type:

Article

Biosensor-Based Approach Identifies Four Distinct Calmodulin-Binding Domains in the G Protein-Coupled Estrogen Receptor 1.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089669

By:

Tran, Quang-Kim;
VerMeer, Mark

Publication type:

Article

Co-Expression of GRK2 Reveals a Novel Conformational State of the µ-Opioid Receptor.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083691

By:

Nickolls, Sarah A.;
Humphreys, Sian;
Clark, Mellissa;
McMurray, Gordon

Publication type:

Article

Membrane Orientation and Binding Determinants of G Protein-Coupled Receptor Kinase 5 as Assessed by Combined Vibrational Spectroscopic Studies.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0082072

By:

Yang, Pei;
Glukhova, Alisa;
Tesmer, John J. G.;
Chen, Zhan

Publication type:

Article

GPR3 Stimulates Aβ Production via Interactions with APP and β-Arrestin2.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074680

By:

Nelson, Christopher D.;
Sheng, Morgan

Publication type:

Article

Splicing Factor Transformer-2β (Tra2β) Regulates the Expression of Regulator of G Protein Signaling 4 (RGS4) Gene and Is Induced by Morphine.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072220

By:

Li, Shu-Jing;
Li, Ya;
Cui, Shi-chao;
Qi, Yao;
Zhao, Jing-Jing;
Liu, Xiao-Yan;
Xu, Ping;
Chen, Xian-Hua

Publication type:

Article

Effects of the Dopamine D2 Allosteric Modulator, PAOPA, on the Expression of GRK2, Arrestin-3, ERK1/2, and on Receptor Internalization.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0070736

By:

Basu, Dipannita;
Tian, Yuxin;
Bhandari, Jayant;
Jiang, Jian Ru;
Hui, Patricia;
Johnson, Rodney L.;
Mishra, Ram K.

Publication type:

Article

Distinct Structural Features of G Protein-Coupled Receptor Kinase 5 (GRK5) Regulate Its Nuclear Localization and DNA-Binding Ability

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062508

By:

Johnson, Laura R.;
Robinson, James D.;
Lester, Katrina N.;
Pitcher, Julie A.

Publication type:

Article

Acidosis Activation of the Proton-Sensing GPR4 Receptor Stimulates Vascular Endothelial Cell Inflammatory Responses Revealed by Transcriptome Analysis.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061991

By:

Dong, Lixue;
Li, Zhigang;
Leffler, Nancy R.;
Asch, Adam S.;
Chi, Jen-Tsan;
Yang, Li V.

Publication type:

Article

Agonism and Antagonism at the Insulin Receptor.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051972

By:

Knudsen, Louise;
Hansen, Bo Falck;
Jensen, Pia;
Åskov Pedersen, Thomas;
Vestergaard, Kirsten;
Schäffer, Lauge;
Blagoev, Blagoy;
Oleksiewicz, Martin B.;
Kiselyov, Vladislav V.;
De Meyts, Pierre

Publication type:

Article

Comparative Analysis of Calcium Spikes upon Activation of Serotonin1A and Purinergic Receptors.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051857

By:

Saxena, Roopali;
Ganguly, Sourav;
Chattopadhyay, Amitabha

Publication type:

Article

The Determination of Importance of Sequences Neighboring the Psi Sequence in Lentiviral Vector Transduction and Packaging Efficiency.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050148

By:

Seon Hee Kim;
Hyun Jeong Jun;
Soo In Jang;
Ji Chang You

Publication type:

Article

Association between Smoking and Latent Tuberculosis in the U.S. Population: An Analysis of the National Health and Nutrition Examination Survey.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049050

By:

Horne, David J.;
Campo, Monica;
Ortiz, Justin R.;
Oren, Eyal;
Arentz, Matthew;
Crothers, Kristina;
Narita, Masahiro

Publication type:

Article

Slow Receptor Dissociation Kinetics Differentiate Macitentan from Other Endothelin Receptor Antagonists in Pulmonary Arterial Smooth Muscle Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047662

By:

Gatfield, John;
Grandjean, Celia Mueller;
Sasse, Thomas;
Clozel, Martine;
Nayler, Oliver

Publication type:

Article

Stabilization of Functional Recombinant Cannabinoid Receptor CB2 in Detergent Micelles and Lipid Bilayers.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046290

By:

Vukoti, Krishna;
Kimura, Tomohiro;
Macke, Laura;
Gawrisch, Klaus;
Yeliseev, Alexei

Publication type:

Article

Targeted Ubiquitination and Degradation of G-Protein-Coupled Receptor Kinase 5 by the DDB1-CUL4 Ubiquitin Ligase Complex.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043997

By:

Ziyan Wu;
Yuejun Chen;
Tong Yang;
Qinqin Gao;
Man Yuan;
Lan Ma;
Hess, Sonja

Publication type:

Article

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040976

By:

Ruffner, Heinz;
Sprunger, Joëlle;
Olga Charlat;
Leighton-Davies, Juliet;
Grosshans, Bianka;
Salathe, Adrian;
Svenja Zietzling;
Beck, Valérie;
Therier, Maxime;
Isken, Andrea;
Yang Xie;
Yue Zhang;
Huaixiang Hao;
Xiaoying Shi;
Dong Liu;
Qinhui Song;
Ieuan Clay;
Gabriele Hintzen;
Tchorz, Jan;
Bouchez, Laure C.

Publication type:

Article