Works about FOCAL adhesion kinase

Results: 1748

Neuregulin-induced HER3 activation drives migration in head and neck squamous cell carcinoma via HER2 and FAK signaling pathways.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 4, p. 1089, doi. 10.1007/s13402-025-01069-2

By:

Lim, Eun Jin;
Yoon, Yu Jeong;
Heo, Jeonghoon;
Kim, Seungwon;
Choi, Yung-Hyun;
Kim, Young-Ho

Publication type:

Article

Growth arrest specific–6 and angiotoxin receptor–like signaling drive oral regenerative wound repair.

Published in:

Science Translational Medicine, 2025, v. 17, n. 805, p. 1, doi. 10.1126/scitranslmed.adk2101

By:

Griffin, Michelle F.;
Cook, Jessica;
Morgan, Annah;
Boffelli, Dario;
Downer, Mauricio;
Spielman, Amanda F.;
Guardino, Nicholas J.;
Guo, Jason L.;
Parker, Jennifer B. L.;
Januszyk, Michael;
Valencia, Caleb;
Kuhnert, Maxwell;
Lu, John;
Zwick, Rachel;
Wan, Derrick C.;
Klein, Ophir D.;
Longaker, Michael T.

Publication type:

Article

The Non-Peptide MAS-R Agonist AVE0991 Alleviates Colitis Severity in Mice and Exhibits an Additive Effect with Azathioprine.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5784, doi. 10.3390/ijms26125784

By:

Khajah, Maitham A.;
Hawai, Sana;
Barakat, Ahmad

Publication type:

Article

Spindle Orientation Regulation Is Governed by Redundant Cortical Mechanosensing and Shape-Sensing Mechanisms.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5730, doi. 10.3390/ijms26125730

By:

Hadjisavva, Rania;
Skourides, Paris A.

Publication type:

Article

Nudel and FAK as Antagonizing Strength Modulators of Nascent Adhesions through Paxillin.

Published in:

PLoS Biology, 2009, v. 7, n. 5, p. 1, doi. 10.1371/journal.pbio.1000116

By:

Yongli Shan;
Lihou Yu;
Yan Li;
Youdong Pan;
Qiangge Zhang;
Fubin Wang;
Jianfeng Chen;
Xueliang Zhu

Publication type:

Article

T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression.

Published in:

PLoS Biology, 2003, v. 1, n. 2, p. 271, doi. 10.1371/journal.pbio.0000053

By:

Roose, Jeroen P.;
Diehn, Maximilian;
Tomlinson, Michael G.;
Lin, Joseph;
Alizadeh, Ash A.;
Botstein, David;
Brown, Patrick O.;
Weiss, Arthur

Publication type:

Article

Antifungal Effect of Long Noncoding RNA 9708-1 in the Vulvovaginal Candidiasis Murine Model.

Published in:

Mycopathologia, 2021, v. 186, n. 2, p. 177, doi. 10.1007/s11046-021-00530-8

By:

Wu, Ying;
Jiang, Lisha;
Zhang, Lingling;
Liu, Xia;
Yan, Lina;
Luan, Ting;
Rui, Can;
Mao, Zhiyuan;
Fan, Chong;
Liu, Yu;
Li, Ping;
Zeng, Xin

Publication type:

Article

The Role of 17β-Estrogen in Candida albicans Adhesion on Human Vaginal Epithelial Cells via FAK Phosphorylation.

Published in:

Mycopathologia, 2020, v. 185, n. 3, p. 425, doi. 10.1007/s11046-020-00440-1

By:

Luan, Ting;
Liu, Xia;
Mao, Pengyuan;
Wang, Xinyan;
Rui, Can;
Yan, Lina;
Wang, Yiquan;
Fan, Chong;
Li, Ping;
Zeng, Xin

Publication type:

Article

Cell density modulates SHC3 expression and survival of human glioblastoma cells through Fak activation.

Published in:

Journal of Neuro-Oncology, 2014, v. 120, n. 2, p. 245, doi. 10.1007/s11060-014-1551-x

By:

Azzalin, Alberto;
Moretti, Elena;
Arbustini, Eloisa;
Magrassi, Lorenzo

Publication type:

Article

The Role of the CXCL12/CXCR4 Signaling Pathway in Regulating Cellular Migration.

Published in:

Microscopy & Microanalysis, 2025, v. 31, n. 2, p. 1, doi. 10.1093/mam/ozaf011

By:

Worden, Austin N;
Pittard, Emma Grace;
Stern, Matt;
Uline, Mark J;
Potts, Jay D

Publication type:

Article

Wogonin inhibits hepatoma cell proliferation by targeting miR‐27b‐5p/YWHAZ axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 12, p. 1, doi. 10.1002/jbt.23508

By:

Ma, Ming‐Yue;
Wang, Qian;
Wang, Shou‐Mei;
Feng, Xiao‐Jun;
Xian, Zhi‐Hong;
Zhang, Shu‐Hui

Publication type:

Article

Corrigendum for "Focal Adhesion Kinase knockdown in Carcinoma‐Associated Fibroblasts Inhibits Oral Squamous Cell Carcinoma Metastasis via Downregulating MCP‐1/CCL2 Expression" (Vol. 29, Issue 2).

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 6, p. 1, doi. 10.1002/jbt.22517

By:

Min, Anjie;
Zhu, Chao;
Wang, Jingyi;
Peng, Shuping;
Shuai, Cijun;
Gao, Shan;
Tang, Zhangui;
Su, Tong

Publication type:

Article

Reduced Expression of Focal Adhesion Kinase in Intrahepatic Cholangiocarcinoma Is Associated with Poor Tumor Differentiation.

Published in:

Oncology, 2006, v. 71, n. 5/6, p. 417, doi. 10.1159/000107109

By:

Ryuji Ohta;
Yo-ichi Yamashita;
Akinobu Taketomi;
Dai Kitagawa;
Yosuke Kuroda;
Shinji Itoh;
Shin-ichi Aishima;
Yoshihiko Maehara

Publication type:

Article

Mutational Analysis of AKT1, AKT2 and AKT3 Genes in Common Human Carcinomas.

Published in:

Oncology, 2006, v. 70, n. 4, p. 285, doi. 10.1159/000096289

By:

Young Hwa Soung;
Jong Woo Lee;
Suk Woo Nam;
Jung Young Lee;
Nam Jin Yoo;
Sug Hyung Lee

Publication type:

Article

Signaling Pathways Involved in Collagen-Induced Disruption of the E-Cadherin Complex during Epithelial-Mesenchymal Transition.

Published in:

Cells Tissues Organs, 2007, v. 185, n. 1-3, p. 180, doi. 10.1159/000101319

By:

Imamichi, Yukiko;
Menke, Andre

Publication type:

Article

A Computational Perspective into Binding Mechanism of a potent FAK Inhibitor as Anticancer Drug Candidate: Insights from Molecular Dynamics Simulations.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 2, p. 239, doi. 10.1142/S2737416524500601

By:

Shogi, F.;
Gholamin, D.;
Razzaghi-Asl, N.

Publication type:

Article

Focal adhesion kinase-mammalian target of rapamycin pathway-mediated different proliferation, migration, and differentiation abilities of satellite cells in Lantang and Landrace piglets.

Published in:

2017

By:

Gao, C.;
Jin, C.;
Yan, H.;
Wang, X.

Publication type:

Abstract

Streptococcus uberis increases apoptosis of bovine mammary epithelial cells (MEC) and decreases integrin and focal adhesion kinase (FAK) mRNA expression.

Published in:

Journal of Animal Science, 2006, v. 84, p. 148

By:

Singh, K.;
Dobson, J.;
Phyn, C.;
Davis, S.;
Farr, V.;
Molenaar, A.

Publication type:

Article

Advanced Computational Pipeline for FAK Inhibitor Discovery: Combining Multiple Docking Methods with MD and QSAR for Cancer Therapy.

Published in:

Computation, 2024, v. 12, n. 11, p. 222, doi. 10.3390/computation12110222

By:

Siyah, Pinar

Publication type:

Article

Gas Plasma Exposure Alters Microcirculation and Inflammation during Wound Healing in a Diabetic Mouse Model.

Published in:

Antioxidants, 2024, v. 13, n. 1, p. 68, doi. 10.3390/antiox13010068

By:

Schmidt, Anke;
Singer, Debora;
Aden, Henrike;
von Woedtke, Thomas;
Bekeschus, Sander

Publication type:

Article

Masseter Muscle Rigidity, Elevated Creatine Kinase, and Rhabdomyolysis Following Succinylcholine Administration: A Case Report.

Published in:

AANA Journal, 2008, v. 76, n. 5, p. 349

By:

Fitzpatrick, Lynn R.

Publication type:

Article

FAK loss reduces BRAF<sup>V600E</sup>-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.94605

By:

Chenxi Gao;
Huaibin Ge;
Shih-Fan Kuan;
Chunhui Cai;
Xinghua Lu;
Esni, Farzad;
Schoen, Robert E.;
Wang, Jing H.;
Chu, Edward;
Jing Hu

Publication type:

Article

Redox takes control: A study of two enzymes in the brain reveals new insights into how redox reactions regulate the activity of protein kinases.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.99765

By:

PLAZA-MENACHO, IVÁN

Publication type:

Article

In silico Discovery of RIOK3 Inhibitors Against Pancreatic Ductal Adenocarcinoma via Molecular Docking, Molecular Dynamics Simulations, and ADMET Prediction.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2024, v. 20, p. 9

By:

Alhussinei, Kawthar;
Othman, Rozana;
Chuancheng Wei;
Abdullah, Iskandar;
Subramaniyan, Vetriselvan

Publication type:

Article

FAK mediates BMP9-induced osteogenic differentiation via Wnt and MAPK signaling pathway in synovial mesenchymal stem cells.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2019, v. 47, n. 1, p. 2641, doi. 10.1080/21691401.2019.1631838

By:

Zheng, Weiwei;
Gu, Xueping;
Sun, Xingwei;
Wu, Qin;
Dan, Hu

Publication type:

Article

Leucine rich repeat containing 15 promotes triple-negative breast cancer proliferation and invasion via the ITGB1/FAK/PI3K signalling pathway.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98661-1

By:

Wu, Xiao;
Liu, Yameng;
Hu, Yinxi;
Su, Fang;
Wang, Zishu;
Chen, Yongxia;
Zhuang, Zhixiang

Publication type:

Article

Focal adhesion kinase promotes aerobic glycolysis in hepatic stellate cells via the cyclin D1/c-Myc/MCT-1 pathway to induce liver fibrosis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-88538-8

By:

Huang, Tao;
Zhou, Ming-Yu;
Zou, Gao-Liang;
Hu, Rui-Han;
Han, Lu;
Zhang, Qing-Xiu;
Zhao, Xue-Ke

Publication type:

Article

Automated Analysis of Cell-Matrix Adhesions in 2D and 3D Environments.

Published in:

Scientific Reports, 2015, p. 8124, doi. 10.1038/srep08124

By:

Broussard, Joshua A.;
Diggins, Nicole L.;
Hummel, Stephen;
Georgescu, Walter;
Quaranta, Vito;
Webb, Donna J.

Publication type:

Article

PACT/RAX Regulates the Migration of Cerebellar Granule Neurons in the Developing Cerebellum.

Published in:

Scientific Reports, 2015, p. 7961, doi. 10.1038/srep07961

By:

Yong, Yue;
Meng, Ya;
Ding, Hanqing;
Fan, Zhiqin;
Tang, Yifen;
Zhou, Chenghua;
Luo, Jia;
Ke, Zun-Ji

Publication type:

Article

RhoA and Membrane Fluidity Mediates the Spatially Polarized Src/FAK Activation in Response to Shear Stress.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07008

By:

Bo Liu;
Shaoying Lu;
Ying-li Hu;
Xiaoling Liao;
Mingxing Ouyang;
Yingxiao Wang

Publication type:

Article

FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06024

By:

Ying-Li Hu;
Shaoying Lu;
Szeto, Kai W.;
Jie Sun;
Yingxiao Wang;
Lasheras, Juan C.;
Shu Chien

Publication type:

Article

Inhibition of FAK Signaling Elicits Lamin A/C-Associated Nuclear Deformity and Cellular Senescence.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00022

By:

Chuang, Hsiang-Hao;
Wang, Pei-Hui;
Niu, Sheng-Wen;
Zhen, Yen-Yi;
Huang, Ming-Shyan;
Hsiao, Michael;
Yang, Chih-Jen

Publication type:

Article

Inhibition of focal adhesion kinase 2 results in a macrophage polarization shift to M2 which attenuates local and systemic inflammation and reduces heterotopic ossification after polysystem extremity trauma.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1280884

By:

Rowe, Cassie J.;
Nwaolu, Uloma;
Salinas, Daniela;
Hong, Jonathan;
Nunez, Johanna;
Lansford, Jefferson L.;
McCarthy, Conor F.;
Potter, Benjamin K.;
Levi, Benjamin H.;
Davis, Thomas A.

Publication type:

Article

Human IL-32qA94V mutant attenuates monocyteendothelial adhesion by suppressing the expression of ICAM-1 and VCAM-1 via binding to cell surface receptor integrin aVb3 and aVb6 in TNF-astimulated HUVECs.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1160301

By:

Jae-Young Park;
Hyo-Min Park;
Seonhwa Kim;
Kyeong-Bae Jeon;
Chae-Min Lim;
Jin Tae Hong;
Do-Young Yoon

Publication type:

Article

Cutting-Edge FAK-targeting PROTACs: design, synthesis, and biological evaluation.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2024, v. 33, n. 9, p. 767, doi. 10.5246/jcps.2024.09.057

By:

Ruifeng Wang;
Xin Zhao;
Hongbao Hou;
Ke Chen;
Shuihua Liu;
Ruyue Ren;
Yunfeng Liu;
Yi Zhang

Publication type:

Article

The Importance of Distinguishing Mucinous and Nonmucinous Bronchioloalveolar Carcinomas.

Published in:

2009

By:

Garfield, David;
Cadranel, Jacques

Publication type:

Editorial

Expression of FAK and PTEN in Bronchioloalveolar Carcinoma and Lung Adenocarcinoma.

Published in:

Lung (0341-2040), 2009, v. 187, n. 2, p. 104, doi. 10.1007/s00408-008-9130-6

By:

Changli Wang;
Ran Yang;
Dongsheng Yue;
Zhenfa Zhang

Publication type:

Article

Focal Adhesion Kinase in Neutrophil-Induced Microvascular Hyperpermeability.

Published in:

Microcirculation, 2005, v. 12, n. 2, p. 223, doi. 10.1080/10739680590905251

By:

Guo, Mingzhang;
Wu, Mack;
Granger, Harris;
Yuan, Sarah

Publication type:

Article

The antiarrhythmic effect of centrally administered rilmenidine involves muscarinic receptors, protein kinase C and mitochondrial signalling pathways.

Published in:

2008

By:

Iwasaki, M.;
Hayashi, Y.;
Kamibayashi, T.;
Yamatodani, A.;
Mashimo, T.

Publication type:

journal article

Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation.

Published in:

2006

By:

da Cruz, Cristiane Monteiro;
Ventura, Ana Lúcia Marques;
Schachter, Julieta;
Costa-Junior, Helio Miranda;
da Silva Souza, Hercules Antonio;
Gomes, Fernanda Ramos;
Coutinho-Silva, Robson;
Ojcius, David M.;
Persechini, Pedro Muanis;
Ventura, Ana Lúcia Marques

Publication type:

journal article

Premature wrinkling of the skin in a 31-year-old woman.

Published in:

Clinical & Experimental Dermatology, 2012, v. 37, n. 3, p. 318, doi. 10.1111/j.1365-2230.2011.04140.x

By:

Singh, S.;
Tailor, A.;
Carton, J.;
Hewitt, C.

Publication type:

Article

Integrin αvβ3 Induces HSP90 Inhibitor Resistance via FAK Activation in KRAS-Mutant Non–Small Cell Lung Cancer.

Published in:

Cancer Research & Treatment, 2022, v. 54, n. 3, p. 767, doi. 10.4143/crt.2021.651

By:

Shinkyo Yoon;
Hannah Yang;
Hyun-Min Ryu;
Eunjin Lee;
Yujin Jo;
Seyoung Seo;
Deokhoon Kim;
Chang Hoon Lee;
Wanlim Kim;
Kyung Hae Jung;
Sook Ryun Park;
Eun Kyung Choi;
Sang-We Kim;
Kang-Seo Park;
Dae Ho Lee

Publication type:

Article

Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation.

Published in:

Journal of Molecular Recognition, 2011, v. 24, n. 2, p. 314, doi. 10.1002/jmr.1062

By:

Siamakpour-Reihani, Sharareh;
Peterson, Tabitha A.;
Bradford, Andrew M.;
Argiros, Haroula J.;
Haas, Laura Lowell;
Lor, Siamee N.;
Haulsee, Zachary M.;
Spuches, Anne M.;
Johnson, Dennis L.;
Rohrschneider, Larry R.;
Shuster, Charles Brad;
Lyons, Barbara A.

Publication type:

Article

Optogenetic activation of mechanical nociceptions to enhance implant osseointegration.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58336-x

By:

Wang, Qijin;
Chen, Yang;
Ding, Haiqi;
Cai, Yuanqing;
Yuan, Xuhui;
Lv, Jianhua;
Huang, Jiagu;
Huang, Jiexin;
Zhang, Chaofan;
Hong, Zihao;
Li, Hongyan;
Huang, Ying;
Lin, Jiamin;
Yuan, Lin;
Lin, Lan;
Yu, Shaolin;
Zhang, Canhong;
Lin, Jianhua;
Li, Wenbo;
Chang, Cheng

Publication type:

Article

Enhanced differentiation of human pluripotent stem cells into pancreatic endocrine cells in 3D culture by inhibition of focal adhesion kinase.

Published in:

Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13287-020-02003-z

By:

Liu, Xiaofang;
Qin, Jinhua;
Chang, Mingyang;
Wang, Shuyong;
Li, Yali;
Pei, Xuetao;
Wang, Yunfang

Publication type:

Article

Long noncoding RNA H19 regulates the therapeutic efficacy of mesenchymal stem cells in rats with severe acute pancreatitis by sponging miR-138-5p and miR-141-3p.

Published in:

Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13287-020-01940-z

By:

Song, Guodong;
Zhou, Jia;
Song, Ruimei;
Liu, Dalu;
Yu, Weidi;
Xie, Wangcheng;
Ma, Zhilong;
Gong, Jian;
Meng, Hongbo;
Yang, Tingsong;
Song, Zhenshun

Publication type:

Article

Diverse cell junctions with unique molecular composition in tissues of a sponge (Porifera).

Published in:

EvoDevo, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13227-019-0139-0

By:

Mitchell, Jennyfer M.;
Nichols, Scott A.

Publication type:

Article

Grammatophyllum speciosum ethanolic extract inhibits proliferation and migration of non-small cell lung cancer cells through focal adhesion kinase/AKT/β-catenin-dependent pathway.

Published in:

Journal of Advanced Pharmaceutical Technology & Research, 2024, v. 15, n. 4, p. 332, doi. 10.4103/JAPTR.JAPTR_116_24

By:

Chowjarean, Verisa;
Harikarnpakdee, Saraporn;
Phiboonchaiyanan, Preeyaporn Plaimee

Publication type:

Article

Fibrosis factor CTGF facilitates VCAM‑1‑dependent monocyte adhesion to osteoarthritis synovial fibroblasts via the FAK and JNK pathways.

Published in:

Molecular Medicine Reports, 2025, v. 31, n. 5, p. N.PAG, doi. 10.3892/mmr.2025.13489

By:

Liu, Shan-Chi;
Law, Yat-Yin;
Wu, Yu-Ying;
Huang, Yuan-Li;
Tsai, Chun-Hao;
Chen, Wei-Cheng;
Tang, Chih-Hsin

Publication type:

Article

lncRNA EZR-AS1 knockdown represses proliferation, migration and invasion of cSCC via the PI3K/AKT signaling pathway.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 1, p. N.PAG

By:

Lu, Di;
Sun, Lingling;
Li, Zhengjun;
Mu, Zhen

Publication type:

Article