Works matching DE "FEBUXOSTAT"

Results: 121

Advanced hybrid computational analysis of febuxostat solubility using machine learning in supercritical processing method.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10221-9

By:

Al Hagbani, Turki;
Alzhrani, Rami M.;
Algarni, Majed Ahmed

Publication type:

Article

Efficacy of different dosages of common uric acid-lowering medications in gout patients: a network meta-analysis of randomized control trials.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1565530

By:

Zheng, Xiaojia;
Xie, Cunxiang;
Fang, Jinying;
Huang, Zhenghui;
Huang, Jian;
Zhao, Luming;
Ye, Guancheng;
Wang, Hailong

Publication type:

Article

Quzhuo tongbi formula for reducing gout flare related to uric acid lowering treatment: Study protocol for a multiple-center, randomized, double-blind, placebo, parallel-controlled clinical trial.

Published in:

PLoS ONE, 2025, v. 19, n. 7, p. 1, doi. 10.1371/journal.pone.0327864

By:

Pan, Hejing;
Li, Xuanlin;
Wu, Shan;
Zhou, Donghai;
Guan, Haojie;
Wu, Haoyu;
Wang, Qiao;
Tang, Yujun;
Hu, Xuanming;
Wang, Meijiao;
Zhou, Mingqian;
Huang, Runyue;
Liu, Lei;
Chen, Yaolong;
Wen, Chengping;
Huang, Lin

Publication type:

Article

Effectiveness of benzbromarone versus febuxostat in gouty patients: a retrospective study.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 7, p. 2121, doi. 10.1007/s10067-022-06110-5

By:

Liu, Dongmei;
Zhou, Binbin;
Li, Zhen;
Zhang, Zhuojun;
Dai, Xiaojuan;
Ji, Zongfei;
Chen, Huiyong;
Sun, Ying;
Jiang, Lindi

Publication type:

Article

Efficacy of febuxostat versus allopurinol and the predictors of achieving target serum urate in a cohort of Thai people with gout.

Published in:

Clinical Rheumatology, 2021, v. 40, n. 1, p. 255, doi. 10.1007/s10067-020-05262-6

By:

Lertnawapan, Ratchaya;
Jatuworapruk, Kanon

Publication type:

Article

Comparison of persistence rates between allopurinol and febuxostat as first-line urate-lowering therapy in patients with gout: an 8-year retrospective cohort study.

Published in:

Clinical Rheumatology, 2020, v. 39, n. 12, p. 3769, doi. 10.1007/s10067-020-05161-w

By:

Kim, Aran;
Kim, Yunkyung;
Kim, Geun-Tae;
Ahn, Eunyoung;
So, Min Wook;
Lee, Seung-Geun

Publication type:

Article

Comparative effect of allopurinol and febuxostat on long-term renal outcomes in patients with hyperuricemia and chronic kidney disease: a systematic review.

Published in:

Clinical Rheumatology, 2020, v. 39, n. 11, p. 3287, doi. 10.1007/s10067-020-05079-3

By:

Hu, Anna M.;
Brown, Jamie N.

Publication type:

Article

Efficacy and safety of febuxostat in Japanese paediatric patients with hyperuricaemia including gout: Phase 2, single arm, open‒label, multicentre studies.

Published in:

Modern Rheumatology, 2025, v. 35, n. 1, p. 194, doi. 10.1093/mr/roae056

By:

Shuichi Ito;
Yo Morita;
Makoto Nitami;
Ryutaro Iwama;
Akihiro Nakajima;
Hisashi Yamanaka;
Masataka Honda

Publication type:

Article

Cardiovascular Safety Evaluation of Febuxostat and Allopurinol: Findings from the FDA Adverse Event Reporting System.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 18, p. 6089, doi. 10.3390/jcm12186089

By:

Bai, Yang;
Wu, Bin;
Gou, Liangwen;
Fang, Zhenwei;
Xu, Ting;
Zhang, Tiejun;
Li, Yuwen

Publication type:

Article

Simple Application and Adherence to Gout Guidelines Enables Disease Control: An Observational Study in French Referral Centres.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 19, p. 5742, doi. 10.3390/jcm11195742

By:

Jauffret, Charlotte;
Ottaviani, Sébastien;
Latourte, Augustin;
Ea, Hang-Korng;
Graf, Sahara;
Lioté, Frédéric;
Bardin, Thomas;
Richette, Pascal;
Pascart, Tristan

Publication type:

Article

The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 133, doi. 10.3390/antiox12010133

By:

Higa, Yoshiki;
Hiasa, Masahiro;
Tenshin, Hirofumi;
Nakaue, Emiko;
Tanaka, Mariko;
Kim, Sooha;
Nakagawa, Motosumi;
Shimizu, So;
Tanimoto, Kotaro;
Teramachi, Jumpei;
Harada, Takeshi;
Oda, Asuka;
Oura, Masahiro;
Sogabe, Kimiko;
Hara, Tomoyo;
Sumitani, Ryohei;
Maruhashi, Tomoko;
Yamagami, Hiroki;
Endo, Itsuro;
Matsumoto, Toshio

Publication type:

Article

Evaluation of Xanthine Oxidase Inhibitors Febuxostat and Allopurinol on Kidney Dysfunction and Histological Damage in Two‐Kidney, One‐Clip (2K1C) Rats.

Published in:

Scientifica, 2025, v. 2025, p. 1, doi. 10.1155/sci5/7932075

By:

Shuvo, Asif Ul Haque;
Alimullah, Mirza;
Jahan, Ishrat;
Mitu, Kaniz Fatima;
Rahman, Md Junaeid;
Akramuddaula, Kazi;
Khan, Ferdous;
Dash, Pritesh Ranjan;
Subhan, Nusrat;
Alam, Md Ashraful;
Gorai, Sukhamoy

Publication type:

Article

Population pharmacokinetic analysis of febuxostat with high focus on absorption kinetics and food effect.

Published in:

BMC Pharmacology & Toxicology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s40360-024-00783-1

By:

Chen, Wenjun;
Jiang, Bo;
Ruan, Zourong;
Yang, Dandan;
Hu, Yin;
Lou, Honggang

Publication type:

Article

Effectiveness and safety of different doses of febuxostat compared with allopurinol in the treatment of hyperuricemia: a meta-analysis of randomized controlled trials.

Published in:

BMC Pharmacology & Toxicology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s40360-023-00723-5

By:

Xie, Hong;
Hu, Nan;
Pan, Ting;
Wu, Jun-Cai;
Yu, Miao;
Wang, Deng-Chao

Publication type:

Article

Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Administration of Verinurad and Febuxostat in Healthy Male Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2019, v. 8, n. 2, p. 179, doi. 10.1002/cpdd.463

By:

Hall, Jesse;
Gillen, Michael;
Yang, Xiaojuan;
Shen, Zancong

Publication type:

Article

Integrating the Quality-by-Design (QbD) Approach in the Development of Febuxostat-loaded Proniosomal Gel for Topical Delivery.

Published in:

Nano Biomedicine & Engineering, 2024, v. 16, n. 4, p. 625, doi. 10.26599/NBE.2024.9290101

By:

Kshirsagar, Rajeshwar V.;
Rajewar, Sujata R.;
Kokil, Shreya S.;
Viswanadh, Matte Kasi;
Patrakar, Ramling G.;
Pawde, Datta Maroti

Publication type:

Article

Comparison of Febuxostat and Allopurinol in the Treatment of Patients with Chronic Kidney Disease Stage 3∼5 with Hyperuricemia.

Published in:

Emergency Medicine International, 2022, p. 1, doi. 10.1155/2022/1177946

By:

Liao, Zhimin;
Xu, Lei;
Wan, Bo;
Wang, Liping;
Zhao, Chengzhi;
Wu, Gang;
Xie, Rui

Publication type:

Article

A rare case of thrombocytopenia secondary to taking febuxostat.

Published in:

Italian Journal of Medicine, 2024, v. 18, n. 2, p. 1, doi. 10.4081/itjm.2024.1724

By:

Di Zio, Isabella;
Cisternino, Rodolfo

Publication type:

Article

Febuxostat provides renoprotection in patients with hyperuricemia or gout: a systematic review and meta-analysis of randomized controlled trials.

Published in:

Annals of Medicine, 2024, v. 56, n. 1, p. 1, doi. 10.1080/07853890.2024.2332956

By:

Xiu Hong Yang;
Bao Long Zhang;
Yun Cheng;
Shun Kun Fu;
Hui Min Jin

Publication type:

Article

Superior effect of allopurinol compared to febuxostat on the retardation of chronic kidney disease progression.

Published in:

PLoS ONE, 2022, v. 17, n. 2, p. 1, doi. 10.1371/journal.pone.0264627

By:

Park, Seokwoo;
Lee, Jung Pyo;
Kim, Dong Ki;
Kim, Yon Su;
Lim, Chun Soo

Publication type:

Article

Effects of Valsartan in Combination with Febuxostat on Serum Uric Acid, high-sensitivity C-reactive protein and Cardiac Function of Patients with Chronic Kidney Disease Plus Hyperuricemia.

Published in:

Indian Journal of Pharmaceutical Sciences, 2020, v. 82, n. 6, p. 1054, doi. 10.36468/pharmaceutical-sciences.739

By:

CHEN WANG;
LIANGLAN SHEN;
FEN ZHANG;
XINGXING FANG;
DONGMEI CHEN;
HUAXING HUANG

Publication type:

Article

Comprehensive Evaluation of OATP‐ and BCRP‐Mediated Drug–Drug Interactions of Methotrexate Using Physiologically‐Based Pharmacokinetic Modeling.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 4, p. 1013, doi. 10.1002/cpt.3329

By:

Hwang, Sejung;
Lee, Yujin;
Jang, Yeonseo;
Cho, Joo‐Youn;
Yoon, Seonghae;
Chung, Jae‐Yong

Publication type:

Article

Impacts of Febuxostat on Cerebral and Cardiovascular Events in Elderly Patients with Hyperuricemia: Post Hoc Analysis of a Randomized Controlled Trial.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 6, p. 1358, doi. 10.1002/cpt.3217

By:

Sugawara, Masahiro;
Kojima, Sunao;
Hisatome, Ichiro;
Matsui, Kunihiko;
Uchiyama, Kazuaki;
Yokota, Naoto;
Tokutake, Eiichi;
Wakasa, Yutaka;
Hiramitsu, Shinya;
Waki, Masako;
Jinnouchi, Hideaki;
Kakuda, Hirokazu;
Hayashi, Takahiro;
Kawai, Naoki;
Mori, Hisao;
Tsujita, Kenichi;
Ohya, Yusuke;
Kimura, Kazuo;
Saito, Yoshihiko;
Ogawa, Hisao

Publication type:

Article

Renoprotective effect of febuxostat on contrast-induced acute kidney injury in chronic kidney disease patients stage 3: randomized controlled trial.

Published in:

BMC Nephrology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12882-023-03114-4

By:

Sarhan, Iman Ibrahim;
Abdellatif, Yasser A.;
Saad, Rania Elsayed;
Teama, Nahla Mohamed

Publication type:

Article

Transition Metal‐Free N−S Bond Cleavage and C−N Bond Activation of Ugi‐Adducts for Rapid Preparation of Primary Amides and α‐Ketoamides.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 53, p. 1, doi. 10.1002/chem.202301541

By:

Liu, Chao;
Van der Eycken, Johan;
Van der Eycken, Erik V.

Publication type:

Article

Chemical Constituents from Achyranthes bidentata and Their Antihyperuricemic Acid Activities.

Published in:

Chemistry of Natural Compounds, 2025, v. 61, n. 1, p. 52, doi. 10.1007/s10600-025-04572-y

By:

Yu, Jinqian;
Wang, Xiao;
Botirov, E. Kh.;
Dong, Hongjing;
Gusakova, S. D.;
Liu, Wei

Publication type:

Article

Switching from allopurinol to febuxostat: efficacy and safety in the treatment of hyperuricemia in renal transplant recipients.

Published in:

Renal Failure, 2019, v. 41, n. 1, p. 595, doi. 10.1080/0886022X.2019.1632717

By:

Li, Yanchun;
Liu, Min;
Zhang, Xuelei;
Lu, Yuewu;
Meng, Juan

Publication type:

Article

Allopurinol versus Febuxostat: A New Approach for the Management of Hepatic Steatosis in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Published in:

Biomedicines, 2023, v. 11, n. 11, p. 3074, doi. 10.3390/biomedicines11113074

By:

Al-Shargi, Amani;
El Kholy, Amal A.;
Adel, Abdulmoneim;
Hassany, Mohamed;
Shaheen, Sara M.

Publication type:

Article

不同剂量百令胶囊联合非布司他对慢性肾功能不全伴高尿酸血症患者肾功能及血脂水平的影响.

Published in:

Progress in Modern Biomedicine, 2020, v. 20, n. 18, p. 3572, doi. 10.13241/j.cnki.pmb.2020.18.039

By:

符薇薇;
陈洁;
陈兴强;
林丽娟;
吴琳虹;
李季芳

Publication type:

Article

非布司他治疗老年高尿酸血症痛风患者的临床疗效及安全性分析.

Published in:

Progress in Modern Biomedicine, 2019, v. 19, n. 19, p. 3780, doi. 10.13241/j.cnki.pmb.2019.19.042

By:

郭洪佩;
范俊;
路臻豪;
张爱霞;
刘伟

Publication type:

Article

非布司他对急性痛风性关节炎患者血清SUA 水平及氧化应激的影响.

Published in:

Progress in Modern Biomedicine, 2018, v. 18, n. 8, p. 1548, doi. 10.13241/j.cnki.pmb.2018.08.031

By:

肖岚;
李江涛;
李强;
李明涵;
陈芍

Publication type:

Article

Effects of febuxostat on serum cytokines IL-1, IL-4, IL-6, IL-8, TNF-α and COX-2.

Published in:

Experimental & Therapeutic Medicine, 2019, v. 17, n. 1, p. 812

By:

Hao, Guohua;
Duan, Wei;
Sun, Jianping;
Liu, Jingyao;
Peng, Bo

Publication type:

Article

PTEN/PI3K/VEGF signaling pathway involved in the protective effect of xanthine oxidase inhibitor febuxostat against endometrial hyperplasia in rats.

Published in:

Human & Experimental Toxicology, 2020, v. 39, n. 9, p. 1224, doi. 10.1177/0960327120914977

By:

Mohamed, MZ;
Baky, MF Abed El;
Hassan, OA;
Mohammed, HH;
Abdel-Aziz, AM

Publication type:

Article

Cocrystal Prediction Based on Deep Forest Model—A Case Study of Febuxostat.

Published in:

Crystals (2073-4352), 2024, v. 14, n. 4, p. 313, doi. 10.3390/cryst14040313

By:

Chen, Jiahui;
Li, Zhihui;
Kang, Yanlei;
Li, Zhong

Publication type:

Article

Efficacy and safety of switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, in hyperuricemic patients with type 2 diabetic kidney disease: Protocol for a single-arm, open-label, prospective, exploratory study.

Published in:

Frontiers in Endocrinology, 2023, v. 13, p. 1, doi. 10.3389/fendo.2022.1042061

By:

Takeshi Osonoi;
Miyoko Saito;
Mitsuru Hosoya;
Satako Douguchi;
Kensuke Ofuchi;
Makoto Katoh

Publication type:

Article

Evaluation of Pharmacokinetic Feasibility of Febuxostat/L-pyroglutamic Acid Cocrystals in Rats and Mice.

Published in:

Pharmaceutics, 2023, v. 15, n. 8, p. 2167, doi. 10.3390/pharmaceutics15082167

By:

Yu, Jeong-Eun;
You, Byoung Hoon;
Bae, Mingoo;
Han, Seung Yon;
Jung, Kiwon;
Choi, Young Hee

Publication type:

Article

Formulation Development of Fast Dissolving Microneedles Loaded with Cubosomes of Febuxostat: In Vitro and In Vivo Evaluation.

Published in:

Pharmaceutics, 2023, v. 15, n. 1, p. 224, doi. 10.3390/pharmaceutics15010224

By:

Patel, Brijesh;
Thakkar, Hetal

Publication type:

Article

Analyzing Alkyl Bromide Genotoxic Impurities in Febuxostat Based on Static Headspace Sampling and GC-ECD.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 4, p. 422, doi. 10.3390/ph17040422

By:

Kavrentzos, Alexandros;
Vastardi, Elli;
Karavas, Evangelos;
Tzanavaras, Paraskevas D.;
Zacharis, Constantinos K.

Publication type:

Article

A novel quality by design approach for development and validation of a green reversed‐phase HPLC method with fluorescence detection for the simultaneous determination of lesinurad, febuxostat, and diflunisal: Application to human plasma.

Published in:

Journal of Separation Science, 2021, v. 44, n. 11, p. 2177, doi. 10.1002/jssc.202100016

By:

Magdy, Galal;
Abdel Hakiem, Ahmed F.;
Belal, Fathalla;
Abdel‐Megied, Ahmed M.

Publication type:

Article

Exploring the binding characteristics of febuxostat, an inhibitor of xanthine oxidase with calf thymus DNA: Multi-spectroscopic methodologies and molecular docking.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2022, v. 41, n. 7, p. 605, doi. 10.1080/15257770.2022.2057534

By:

Lu, Xin-Yan;
Lou, Yan-Yue;
Zhou, Kai-Li;
Jiang, Shao-Liang;
Shi, Jie-Hua

Publication type:

Article

Febuxostat, an inhibitor of xanthine oxidase, ameliorates ionizing radiation-induced lung injury by suppressing caspase-3, oxidative stress and NF-κB.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 6, p. 2586, doi. 10.1080/01480545.2021.1977315

By:

Raeispour, Marziyeh;
Talebpour Amiri, Fereshteh;
Farzipour, Soghra;
Ghasemi, Arash;
Hosseinimehr, Seyed Jalal

Publication type:

Article

Celebrating Versatility: Febuxostat's Multifaceted Therapeutic Application.

Published in:

Life (2075-1729), 2023, v. 13, n. 11, p. 2199, doi. 10.3390/life13112199

By:

Kraev, Krasimir Iliev;
Geneva-Popova, Mariela Gencheva;
Hristov, Bozhidar Krasimirov;
Uchikov, Petar Angelov;
Popova-Belova, Stanislava Dimitrova;
Kraeva, Maria Ilieva;
Basheva-Kraeva, Yordanka Mincheva;
Stoyanova, Nina Staneva;
Mitkova-Hristova, Vesela Todorova

Publication type:

Article

Effects of Febuxostat Therapy on Circulating Adipokine Profiles in Patients with Overweight or Obesity and Asymptomatic Hyperuricemia: A Randomized Controlled Study.

Published in:

Obesity Facts: The European Journal of Obesity, 2024, v. 17, n. 5, p. 524, doi. 10.1159/000540701

By:

Dong, Meijuan;
Cui, Zhaohui;
Liu, Yuanyuan;
Bu, Yanlong;
An, Kun;
Mao, Li

Publication type:

Article

A Review of Hyperuricaemia Management with Febuxostat: Dosage Titration, Monitoring and Maintenance.

Published in:

Journal of Clinical & Diagnostic Research, 2022, v. 16, n. 1, p. 7, doi. 10.7860/JCDR/2022/51970.15876

By:

RAY, DEEPAK SHANKAR;
NAIR, TINY;
DARGAD, RAMESH;
DHAR, VERINDER

Publication type:

Article

Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats.

Published in:

Journal of Applied Biomedicine, 2023, v. 21, n. 2, p. 80, doi. 10.32725/jab.2023.009

By:

Kakimoto, Mai;
Fujii, Moe;
Sato, Ikumi;
Honma, Koki;
Nakayama, Hinako;
Kirihara, Sora;
Fukuoka, Taketo;
Ran, Shang;
Hirohata, Satoshi;
Kitamori, Kazuya;
Yamamoto, Shusei;
Watanabe, Shogo

Publication type:

Article

Effects of Venlafaxine, Risperidone and Febuxostat on Cuprizone-Induced Demyelination, Behavioral Deficits and Oxidative Stress.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 7183, doi. 10.3390/ijms22137183

By:

Mihai, Dragos Paul;
Ungurianu, Anca;
Ciotu, Cosmin I.;
Fischer, Michael J. M.;
Olaru, Octavian Tudorel;
Nitulescu, George Mihai;
Andrei, Corina;
Zbarcea, Cristina Elena;
Zanfirescu, Anca;
Seremet, Oana Cristina;
Chirita, Cornel;
Negres, Simona

Publication type:

Article

Febuxostat attenuates aluminum chloride-induced hepatorenal injury in rats with the impact of Nrf2, Crat, Car3, and MNK-mediated apoptosis.

Published in:

Environmental Science & Pollution Research, 2023, v. 30, n. 35, p. 83356, doi. 10.1007/s11356-023-28182-9

By:

Sedik, Ahmed A.;
Hassan, Soha A.;
Shafey, Heba I.;
Khalil, Wagdy K. B.;
Mowaad, Noha A.

Publication type:

Article

Development Of Immediate Release Capsule And Immediate Release Tablet Formulated Using Spray Dried Amorphous Solid Dispersion Of Febuxostat.

Published in:

International Journal of Pharmaceutical Research (09752366), 2021, v. 13, n. 2, p. 1741, doi. 10.31838/ijpr/2021.13.02.237

By:

PATEL, VAISHALI;
PATEL, ANITA;
SHAH, ASHISH

Publication type:

Article

Effects of the xanthine oxidase inhibitor, febuxostat, on the expression of monocyte chemoattractant protein‐1 and synchronous genes in MDCK cells treated with calcium oxalate monohydrate crystals.

Published in:

International Journal of Urology, 2021, v. 28, n. 3, p. 339, doi. 10.1111/iju.14450

By:

Miyazawa, Katsuhito;
Nakai, Dan;
Nakamura, Yuka;
Tatsuno, Takanori;
Inoue, Shinya;
Nakazawa, Yusuke;
Ishigaki, Yasuhito

Publication type:

Article

Flexor Tendon Rupture Secondary to Gout.

Published in:

Archives of Plastic Surgery, 2023, v. 50, n. 5, p. 492, doi. 10.1055/s-0043-1772756

By:

Lynn, Jeremy V.;
Strong, Amy L.;
Chung, Kevin C.

Publication type:

Article