Works about FATTY acid synthases

Results: 802

Arid1a deficiency sensitises pancreatic cancer to fatty acid synthase inhibition.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 7, p. 1, doi. 10.1002/ctm2.70394

By:

Kuo, Tzu‐Lei;
Hou, Ya‐Chin;
Shan, Yan‐Shen;
Chen, Li‐Tzong;
Hung, Wen‐Chun

Publication type:

Article

Genome-Wide Analysis of KCS Gene Family in Ginkgo biloba L. and Functional Identification of KCS7 in Oleic Acid Synthesis.

Published in:

Genes, 2025, v. 16, n. 7, p. 773, doi. 10.3390/genes16070773

By:

Zhang, Xingyu;
Fan, Kaifang;
Feng, Zhi;
Yao, Zhi;
Li, Jinyuan;
Zhang, Shuguang;
Mi, Xiaoqin;
Wu, Fuwen;
Wang, Yiqiang;
Li, Meng

Publication type:

Article

Identification of lactylation-associated immune and metabolic regulators in bladder cancer via integrated bulk and single-cell transcriptomics.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1604758

By:

Chen, Yanjun;
Sun, Yu;
Liu, Xiaoyan

Publication type:

Article

Small molecule UCM05 inhibits HSV-2 infection via targeting viral glycoproteins and fatty acid synthase with potentiating antiviral immunity.

Published in:

Virology Journal, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12985-025-02867-8

By:

Li, Songshan;
Li, Minghan;
Cai, Yantong;
Xian, Jun;
Zhu, Rongrong;
Yang, Chan;
Zhang, Xin;
Ren, Shuya;
Yu, Aijiao;
Liu, Shuwen;
Yang, Bin

Publication type:

Article

Activated TBK1 promotes ACSL1-mediated microglia lipid droplet accumulation and neuroinflammation in Parkinson's disease.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03517-0

By:

Han, Chunlei;
Wang, Huizhi;
Zhang, Moxuan;
Wu, Liuliu;
Wang, Anni;
Yang, Pengda;
Gao, Yuan;
Zhang, Chaonan;
Gao, Jianing;
Xue, Tao;
Du, Tingting;
Ji, Yucheng;
Shi, Lin;
Zhang, Chunkui;
Li, Renpeng;
Xiao, Yilei;
Zhang, Jianguo;
Meng, Fangang

Publication type:

Article

Fatty acid synthase regulates lipid metabolism in Panonychus citri (McGregor) (Acari: Tetranychidae) and its potential for mite control.

Published in:

Pest Management Science, 2025, v. 81, n. 8, p. 4382, doi. 10.1002/ps.8796

By:

Xin, Tianrong;
Xie, Ying;
Jiang, Chengyu;
Jin, Mengru;
Wang, Haifeng;
Xia, Bin

Publication type:

Article

Research advances in intramuscular fat deposition and chicken meat quality: genetics and nutrition.

Published in:

Journal of Animal Science & Biotechnology, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s40104-025-01234-5

By:

Song, Jianlou;
Lv, Zengpeng;
Guo, Yuming

Publication type:

Article

Genomic evolution and ecotype divergence in thraustochytrids: insights from comparative genomics and phylogenomics.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1608951

By:

Wen, Yingying;
Zhu, Xingyu;
Li, Jiaqian;
Liu, Xiuping;
Li, Qixuan;
Wang, Guangyi

Publication type:

Article

Interaction Between Ruminal Acetate Infusion and Diet Fermentability on Milk Fat Production in Dairy Cows.

Published in:

Animals (2076-2615), 2025, v. 15, n. 13, p. 1931, doi. 10.3390/ani15131931

By:

Urrutia, Natalie L.;
Muñoz, Camila;
Ungerfeld, Emilio M.;
Cisterna, Claudia;
Harvatine, Kevin J.

Publication type:

Article

Isolation, Characterization and Probiotic Properties of Levilactobacillus brevis FS1 from Fermented Food and Its Impact on Differentiation and Fat Deposition.

Published in:

Indian Journal of Microbiology, 2025, v. 65, n. 2, p. 1079, doi. 10.1007/s12088-025-01451-6

By:

Gatasheh, Mansour K.

Publication type:

Article

Fatty acid synthase-derived lipid stores support breast cancer metastasis.

Published in:

Cancer & Metabolism, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40170-025-00404-3

By:

Andolino, Chaylen;
Cotul, Eylem Kulkoyluoglu;
Xianyu, Zilin;
Li, Yun;
Bhat, Divya;
Ayers, Mitchell;
Buhman, Kimberly K.;
Hursting, Stephen D.;
Wendt, Michael K.;
Teegarden, Dorothy

Publication type:

Article

The apicoplast localized isocitrate dehydrogenase is needed for de novo fatty acid synthesis in the apicoplast of Toxoplasma gondii.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1542122

By:

Pan, Ke;
Zeng, Ao;
Ruan, Xiaodie;
Mo, Xinyu;
Shen, Bang;
Zhao, Junlong;
Zhou, Yanqin

Publication type:

Article

Riplet promotes lipid metabolism changes associated with CD8 T cell exhaustion and anti–PD-1 resistance in hepatocellular carcinoma.

Published in:

Science Immunology, 2025, v. 10, n. 108, p. 1, doi. 10.1126/sciimmunol.ado3485

By:

Liang, Junnan;
Liao, Jingyu;
Chang, Ruizhi;
Jia, Wenlong;
Li, Ganxun;
Chen, Zeyu;
Wu, Hang;
Zhu, Chang;
Wen, Jingyuan;
Huang, Qibo;
Gao, Han;
Gui, Zichen;
Xu, Weiqi;
Liang, Huifang;
Liu, Qiumeng;
Xu, Dafeng;
Li, Zifu;
Xia, Limin;
Chen, Xiaoping;
Huang, Zhao

Publication type:

Article

Comparative transcriptomic analysis reveals the important role of hepatic fatty acid metabolism in the acute heat stress response in chickens.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11832-2

By:

Mei, Zi;
Song, Zhenquan;
Zhou, Haobo;
Zheng, Bin;
Xiong, Yiwei;
Sheng, Zheya;
Gong, Yanzhang

Publication type:

Article

Elucidating the Role of FASN in Lung Cancer Stem Cells in Sensitive and Resistant EGFR-Mutated Non-Small Cell Lung Cancer Cells.

Published in:

Lung Cancer: Targets & Therapy, 2025, v. 16, p. 57, doi. 10.2147/LCTT.S512936

By:

Polonio-Alcalá, Emma;
Ausellé-Bosch, Sira;
Riesco-Llach, Gerard;
Novales, Pablo;
Feliu, Lidia;
Planas, Marta;
Ciurana, Joaquim;
Puig, Teresa

Publication type:

Article

Downregulation of S6 Kinase and Hedgehog–Gli1 by Inhibition of Fatty Acid Synthase in AML with FLT3-ITD Mutation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5721, doi. 10.3390/ijms26125721

By:

Kebenko, Maxim;
Zhuang, Ruimeng;
Hoffer, Konstantin;
Worthmann, Anna;
Horn, Stefan;
Kriegs, Malte;
Vorwerk, Jan;
von Bubnoff, Nikolas;
Khandanpour, Cyrus;
Gebauer, Niklas;
Gorantla, Sivahari Prasad;
Fiedler, Walter;
Bokemeyer, Carsten;
Jücker, Manfred

Publication type:

Article

Calibration of NIRS for the Estimation of Fatty Acids in Brassica Juncea.

Published in:

Journal of the American Oil Chemists' Society (JAOCS), 2016, v. 93, n. 5, p. 673, doi. 10.1007/s11746-016-2802-0

By:

Kaur, Balraj;
Sangha, Manjeet K.;
Kaur, Gurpreet

Publication type:

Article

Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells.

Published in:

Liver International, 2017, v. 37, n. 1, p. 80, doi. 10.1111/liv.13183

By:

Cao, Dan;
Song, Xinhua;
Che, Li;
Li, Xiaolei;
Pilo, Maria G.;
Vidili, Gianpaolo;
Porcu, Alberto;
Solinas, Antonio;
Cigliano, Antonio;
Pes, Giovanni M.;
Ribback, Silvia;
Dombrowski, Frank;
Chen, Xin;
Li, Lei;
Calvisi, Diego F.

Publication type:

Article

Application of chromatography technology in the separation of active alkaloids from Hypecoum leptocarpum and their inhibitory effect on fatty acid synthase.

Published in:

Journal of Separation Science, 2015, v. 38, n. 23, p. 4063, doi. 10.1002/jssc.201500848

By:

Zhang, Qiulong;
Luan, Guangxiang;
Ma, Tao;
Hu, Na;
Suo, Yourui;
Wang, Xiaoyan;
Ma, Xiaofeng;
Ding, Chenxu

Publication type:

Article

Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 2, p. 277, doi. 10.1007/s11060-014-1452-z

By:

Grube, Susanne;
Dünisch, Pedro;
Freitag, Diana;
Klausnitzer, Maren;
Sakr, Yasser;
Walter, Jan;
Kalff, Rolf;
Ewald, Christian

Publication type:

Article

Fatty acid synthase is a predictive marker for aggressiveness in meningiomas.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 2, p. 399, doi. 10.1007/s11060-012-0907-3

By:

Makino, Keishi;
Nakamura, Hideo;
Hide, Taku-ichiro;
Yano, Shigetoshi;
Kuroda, Jun-ichiro;
Iyama, Ken-ichi;
Kuratsu, Jun-ichi

Publication type:

Article

Development of Schizochytrium sp. strain HS01 with high-DHA and low-saturated fatty acids production by multi-pronged adaptive evolution.

Published in:

Biotechnology Letters, 2023, v. 45, n. 9, p. 1147, doi. 10.1007/s10529-023-03378-8

By:

Zhong, Huichang;
Zhang, Meng;
Chen, Liyi;
Liu, Weifeng;
Tao, Yong

Publication type:

Article

Circ_0018909 knockdown inhibits the development of pancreatic cancer via the miR‐545‐3p/FASN axis and reduces macrophage polarization to M2.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 4, p. 1, doi. 10.1002/jbt.23293

By:

Song, Yinxue;
Wang, Jun;
Xu, Jing;
Gao, Ye;
Xu, Zhichao

Publication type:

Article

The impact of sericin on inflammation, oxidative stress, and lipid metabolism in female rats with experimental knee osteoarthritis.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 7, p. 2307, doi. 10.1007/s10067-024-06987-4

By:

Gundogdu, Gulsah;
Kilic-Erkek, Ozgen;
Gundogdu, Koksal

Publication type:

Article

Comparative metabolomics analysis investigating the impact of melatonin-enriched diet on energy metabolism in the crayfish, Cherax destructor.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2023, v. 193, n. 6, p. 615, doi. 10.1007/s00360-023-01518-0

By:

Yang, Ying;
Tian, Jiangtao;
Xu, Wenyue;
Ping, Cuobaima;
Du, Xinglin;
Ye, Yucong;
Zhu, Bihong;
Huang, Yizhou;
Li, Yiming;
Jiang, Qichen;
Zhao, Yunlong

Publication type:

Article

fadD deletion and fadL overexpression in Escherichia coli increase hydroxy long-chain fatty acid productivity.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 21, p. 8917, doi. 10.1007/s00253-014-5974-2

By:

Bae, Jin;
Park, Beom;
Jung, Eunok;
Lee, Pyung-Gang;
Kim, Byung-Gee

Publication type:

Article

Fatty Acid Synthase Is a Potential Therapeutic Target in Estrogen Receptor-/Progesterone Receptor-Positive Endometrioid Endometrial Cancer.

Published in:

Oncology, 2013, v. 84, n. 3, p. 166, doi. 10.1159/000342967

By:

Rahman, Mohammed Tanjimur;
Nakayama, Kentaro;
Ishikawa, Masako;
Rahman, Munmun;
Katagiri, Hiroshi;
Katagiri, Atsuko;
Ishibashi, Tomoka;
Iida, Kouji;
Miyazaki, Kohji

Publication type:

Article

The Effect of Fatty Acid Synthase (FASN) Depletion in Pulmonary Metastatic Formation in Breast Cancer Murine Models.

Published in:: Journal of Purdue Undergraduate Research, 2022, v. 12, p. 148, doi. 10.7771/2158-4052.1549
Publication type:: Article

The b-ZIP transcription factor, FgBzip16, is essential for fungal development, ascospore discharge, and pathogenicity by modulating fatty acid metabolism in Fusarium graminearum.

Published in:

Phytopathology Research, 2023, v. 5, n. 1, p. 1, doi. 10.1186/s42483-023-00190-0

By:

Li, Bing;
Shen, Yuhe;
Zhu, Yupan;
Yang, Lingling;
Ma, Ruonan;
Sun, Hao;
Liang, Jingang;
Chen, Kangkang;
Jiao, Zhen;
Yang, Wenchao

Publication type:

Article

Enhanced Inhibition of Adipogenesis by Chrysin via Modification in Redox Balance, Lipogenesis, and Transcription Factors in 3T3-L1 Adipocytes in Comparison with Hesperidin.

Published in:

Journal of the American Nutrition Association, 2022, v. 41, n. 8, p. 758, doi. 10.1080/07315724.2021.1961641

By:

John, Cordelia Mano;
Arockiasamy, Sumathy

Publication type:

Article

AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-024-01352-y

By:

Yang, Yang;
Li, Dan;
Liu, Zhigang;
Zhou, Kai;
Li, Wenxing;
Yang, Yanqi;
Sun, Ruifang;
Li, Yulong

Publication type:

Article

AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-024-01352-y

By:

Yang, Yang;
Li, Dan;
Liu, Zhigang;
Zhou, Kai;
Li, Wenxing;
Yang, Yanqi;
Sun, Ruifang;
Li, Yulong

Publication type:

Article

Author Index Volume 23 (2024).

Published in:: Journal of Computational Biophysics & Chemistry, 2024, v. 23, n. 10, p. 1389, doi. 10.1142/S2737416524990011
Publication type:: Article

Computational Screening of Potential Fatty Acid Synthase Inhibitors as Broad-Spectrum Antiviral Agents.

Published in:

Journal of Computational Biophysics & Chemistry, 2024, v. 23, n. 2, p. 223, doi. 10.1142/S2737416523500606

By:

Xu, Shaohua;
Yuan, Huicheng;
Li, Ling;
Yang, Kai;
Zhao, Liangcun

Publication type:

Article

Influence of polysorbate 80 and cyclopropane fatty acid synthase activity on lactic acid production by Lactobacillus casei ATCC 334 at low pH.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2014, v. 41, n. 3, p. 545, doi. 10.1007/s10295-013-1391-2

By:

Broadbent, J.;
Oberg, T.;
Hughes, J.;
Ward, R.;
Brighton, C.;
Welker, D.;
Steele, J.

Publication type:

Article

Monascus secondary metabolites: production and biological activity.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 2, p. 169, doi. 10.1007/s10295-012-1216-8

By:

Patakova, Petra

Publication type:

Article

FASN promotes lipid metabolism and progression in colorectal cancer via the SP1/PLA2G4B axis.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02409-9

By:

Liu, Xin;
Lu, Jiachun;
Ni, Xiangyu;
He, Yuxin;
Wang, Jiayu;
Deng, Zilin;
Zhang, Guangbo;
Shi, Tongguo;
Chen, Weichang

Publication type:

Article

Targeting Caveolin-1 for enhanced rotator cuff repair: findings from single-cell RNA sequencing.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02359-2

By:

Fang, Shanhong;
Wu, Songye;
Chen, Peng

Publication type:

Article

Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02184-z

By:

Cuyàs, Elisabet;
Pedarra, Stefano;
Verdura, Sara;
Pardo, Miguel Angel;
Espin Garcia, Roderic;
Serrano-Hervás, Eila;
Llop-Hernández, Àngela;
Teixidor, Eduard;
Bosch-Barrera, Joaquim;
López-Bonet, Eugeni;
Martin-Castillo, Begoña;
Lupu, Ruth;
Pujana, Miguel Angel;
Sardanyès, Josep;
Alarcón, Tomás;
Menendez, Javier A.

Publication type:

Article

Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-023-01770-x

By:

Zhang, Chi;
Zhang, Yue;
Dong, Yan;
Zi, Ruiyang;
Wang, Yijie;
Chen, Yanrong;
Liu, Chengxiang;
Wang, Junyi;
Wang, Xuesong;
Li, Jianjun;
Liang, Houjie;
Ou, Juanjuan

Publication type:

Article

Exploring the relationship between copper metabolism and adipose tissue in late-stage finishing steers.

Published in:

Journal of Animal Science, 2025, v. 103, p. 208, doi. 10.1093/jas/skaf102.228

By:

Henderson, Jacob A.;
Messersmith, Elizabeth M.;
Rients, Emma L.;
Smercheck, Dathan T.;
McGill, Jodi;
Hansen, Stephanie L.

Publication type:

Article

In silico analysis of polyphenols modulate bovine PPARγ to increase milk fat synthesis in dairy cattle via the MAPK signaling pathways.

Published in:

Journal of Animal Science, 2024, v. 102, p. 1, doi. 10.1093/jas/skae248

By:

Safdar, Muhammad;
Hassan, Faizul;
Khan, Muhammad Sajjad;
Khan, Aneeb Hassan;
Junejo, Yasmeen;
Ozaslan, Mehmet;
Arain, Muhammad Asif;
Behan, Atique Ahmed

Publication type:

Article

Dietary manganese supplementation decreases hepatic lipid deposition by regulating gene expression and enzyme activity involved in lipid metabolism in the liver of broilers.

Published in:

Journal of Animal Science, 2024, v. 102, p. 1, doi. 10.1093/jas/skae235

By:

Yang, Ke;
Cui, Xiaoyan;
Hu, Yangyang;
Feng, Xinyu;
Chen, Wenpeng;
Zhang, Weiyun;
Zhang, Liyang;
Li, Sufen;
Hu, Yun;
Li, Tingting;
Wang, Shengchen;
Luo, Xugang

Publication type:

Article

Effects of cottonseed meal on performance, gossypol residue, liver function, lipid metabolism, and cecal microbiota in geese.

Published in:

Journal of Animal Science, 2023, v. 101, n. 1, p. 1, doi. 10.1093/jas/skad020

By:

Yu, Jun;
Yang, Haiming;
Sun, Qingyu;
Xu, Xuean;
Yang, Zhi;
Wang, Zhiyue

Publication type:

Article

Effect of maternal dietary starch-to-fat ratio and daily energy intake during late pregnancy on the performance and lipid metabolism of primiparous sows and newborn piglets.

Published in:

Journal of Animal Science, 2022, v. 100, n. 4, p. 1, doi. 10.1093/jas/skac033

By:

Wang, Wenhui;
Wang, Zijie;
Ming, Dongxu;
Huang, Caiyun;
Xu, Song;
Li, Zhe;
Wang, Zhenyu;
Liu, Hu;
Zeng, Xiangfang;
Wang, Fenglai

Publication type:

Article

Insulin signaling and antioxidant proteins in adipose tissue explants from dairy cows challenged with hydrogen peroxide are altered by supplementation of arginine or arginine plus methionine.

Published in:

Journal of Animal Science, 2022, v. 100, n. 3, p. 1, doi. 10.1093/jas/skac036

By:

Ma, Nana;
Liang, Yusheng;
Cardoso, Fabiana F;
Parys, Claudia;
Cardoso, Felipe C;
Shen, Xiangzhen;
Loor, Juan J

Publication type:

Article

Downregulated angiopoietin-like protein 8 production at calving related to changes in lipid metabolism in dairy cows.

Published in:

Journal of Animal Science, 2018, v. 96, n. 7, p. 2646, doi. 10.1093/jas/sky162

By:

Nakano, Misato;
Suzuki, Yutaka;
Haga, Satoshi;
Yamauchi, Eri;
Kim, Dahye;
Nishihara, Koki;
Nakajima, Keiichi;
Gotoh, Takafumi;
Park, Seungju;
Baik, Myunggi;
Katoh, Kazuo;
Roh, Sanggun

Publication type:

Article

Muscle lipid metabolism in two rabbit lines divergently selected for intramuscular fat.

Published in:

Journal of Animal Science, 2017, v. 95, n. 6, p. 2576, doi. 10.2527/jas2017.1371

By:

Martínez-Álvaro, M.;
Agha, S.;
Blasco, A.;
Hernández, P.

Publication type:

Article

Dietary whole and cracked linseed increases the proportion of oleic and α-linolenic acids in adipose tissues and decreases stearoyl-coenzyme A desaturase, acetyl-coenzyme A carboxylase, and fatty acid synthase gene expression in the longissimus thoracis muscle of Yanbian Yellow cattle

Published in:

Journal of Animal Science, 2017, v. 95, n. 2, p. 718, doi. 10.2527/jas.2016.1050

By:

Li, X. Z.;
Yan, C. G.;
Yu, J.;
Gao, Q. S.;
Choi, S. H.;
Shin, J. S.;
Smith, S. B.

Publication type:

Article

Carthamus tinctorius L. (Safflower) Flower Extract Attenuates Hepatic Injury and Steatosis in a Rat Model of Type 2 Diabetes Mellitus via Nrf2-Dependent Hypoglycemic, Antioxidant, and Hypolipidemic Effects.

Published in:

Antioxidants, 2024, v. 13, n. 9, p. 1098, doi. 10.3390/antiox13091098

By:

Alshareef, Nuha Saad;
AlSedairy, Sahar Abdulaziz;
Al-Harbi, Laila Naif;
Alshammari, Ghedeir M.;
Yahya, Mohammed Abdo

Publication type:

Article