Works matching DE "ENZYME promiscuity"

Results: 37

Substrate promiscuity of secondary metabolite enzymes: prenylation of hydroxynaphthalenes by fungal indole prenyltransferases.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 92, n. 4, p. 737, doi. 10.1007/s00253-011-3351-y

By:

Yu, Xia;
Xie, Xiulan;
Li, Shu-Ming

Publication type:

Article

Molecular signatures-based prediction of enzyme promiscuity.

Published in:

Bioinformatics, 2010, v. 26, n. 16, p. 2012, doi. 10.1093/bioinformatics/btq317

By:

Carbonell, Pablo;
Faulon, Jean-Loup

Publication type:

Article

Exploiting enzyme promiscuity to shape plant specialized metabolism.

Published in:

Journal of Experimental Botany, 2019, v. 70, n. 5, p. 1435, doi. 10.1093/jxb/erz025

By:

Kreis, Wolfgang;
Munkert, Jennifer

Publication type:

Article

Multifunctional enzymes in archaea: promiscuity and moonlight.

Published in:

Extremophiles, 2013, v. 17, n. 2, p. 193, doi. 10.1007/s00792-012-0509-1

By:

Jia, Baolei;
Cheong, Gang-Won;
Zhang, Shihong

Publication type:

Article

Mechanism-Guided Discovery of an Esterase Scaffold with Promiscuous Amidase Activity.

Published in:

Catalysts (2073-4344), 2016, v. 6, n. 6, p. 90, doi. 10.3390/catal6060090

By:

Kürten, Charlotte;
Carlberg, Bengt;
Syrén, Per-Olof

Publication type:

Article

Neuronal Expression of the Human Neuropeptide S Receptor NPSR1 Identifies NPS-Induced Calcium Signaling Pathways.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117319

By:

Erdmann, Frank;
Kügler, Sebastian;
Blaesse, Peter;
Lange, Maren D.;
Skryabin, Boris V.;
Pape, Hans-Christian;
Jüngling, Kay

Publication type:

Article

Active Site Loop Conformation Regulates Promiscuous Activity in a Lactonase from Geobacillus kaustophilus HTA426.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0115130

By:

Zhang, Yu;
An, Jiao;
Yang, Guang-Yu;
Bai, Aixi;
Zheng, Baisong;
Lou, Zhiyong;
Wu, Geng;
Ye, Wei;
Chen, Hai-Feng;
Feng, Yan;
Manco, Giuseppe

Publication type:

Article

BioGPS Descriptors for Rational Engineering of Enzyme Promiscuity and Structure Based Bioinformatic Analysis.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109354

By:

Ferrario, Valerio;
Siragusa, Lydia;
Ebert, Cynthia;
Baroni, Massimo;
Foscato, Marco;
Cruciani, Gabriele;
Gardossi, Lucia

Publication type:

Article

Methanosarcina acetivorans C2A Topoisomerase IIIα, an Archaeal Enzyme with Promiscuity in Divalent Cation Dependence.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026903

By:

Morales, Raymond;
Sriratana, Palita;
Jing Zhang;
Cann, Isaac K. O.

Publication type:

Article

On the Origins of Enzyme Inhibitor Selectivity and Promiscuity: A Case Study of Protein Kinase Binding to Staurosporine.

Published in:

Chemical Biology & Drug Design, 2009, v. 74, n. 1, p. 16, doi. 10.1111/j.1747-0285.2009.00832.x

By:

Tanramluk, Duangrudee;
Schreyer, Adrian;
Pitt, William R.;
Blundell, Tom L.

Publication type:

Article

In silico ribozyme evolution in a metabolically coupled RNA population.

Published in:

Biology Direct, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13062-015-0049-6

By:

Könnyu, Balázs;
Szilágyi, András;
Czárán, Tamás;
Jékely, Gáspár;
Poole, Anthony;
Mulkidjanian, Armen

Publication type:

Article

Profiling the orphan enzymes.

Published in:

Biology Direct, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1745-6150-9-10

By:

Sorokina, Maria;
Stam, Mark;
Médigue, Claudine;
Lespinet, Olivier;
Vallenet, David

Publication type:

Article

Enzyme promiscuity shapes adaptation to novel growth substrates.

Published in:

Molecular Systems Biology, 2019, v. 15, n. 4, p. N.PAG, doi. 10.15252/msb.20188462

By:

Guzmán, Gabriela I;
Sandberg, Troy E;
LaCroix, Ryan A;
Nyerges, Ákos;
Papp, Henrietta;
de Raad, Markus;
King, Zachary A;
Hefner, Ying;
Northen, Trent R;
Notebaart, Richard A;
Pál, Csaba;
Palsson, Bernhard O;
Papp, Balázs;
Feist, Adam M

Publication type:

Article

Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors.

Published in:

Nature Neuroscience, 2014, v. 17, n. 12, p. 1720, doi. 10.1038/nn.3871

By:

Heller, Elizabeth A;
Cates, Hannah M;
Peña, Catherine J;
Sun, Haosheng;
Shao, Ningyi;
Feng, Jian;
Golden, Sam A;
Herman, James P;
Walsh, Jessica J;
Mazei-Robison, Michelle;
Ferguson, Deveroux;
Knight, Scott;
Gerber, Mark A;
Nievera, Christian;
Han, Ming-Hu;
Russo, Scott J;
Tamminga, Carol S;
Neve, Rachael L;
Shen, Li;
Zhang, H Steve

Publication type:

Article

Exploration of the Substrate Promiscuity of Biosynthetic Tailoring Enzymes as a New Source of Structural Diversity for Polyene Macrolide Antifungals.

Published in:

ChemCatChem, 2015, v. 7, n. 3, p. 490, doi. 10.1002/cctc.201402773

By:

Santos‐Aberturas, Javier;
Engel, Jennifer;
Dickerhoff, Jonathan;
Dörr, Mark;
Rudroff, Florian;
Weisz, Klaus;
Bornscheuer, Uwe T.

Publication type:

Article

Hydroxynitrile Lyases Do Not Catalyse the Promiscuous Addition of Cyanide to Imines.

Published in:

ChemCatChem, 2013, v. 5, n. 6, p. 1304, doi. 10.1002/cctc.201200804

By:

Torrelo, Guzman;
Jin, JianfENg;
Hanefeld, Ulf

Publication type:

Article

Promiscuity in the part-phosphorylative Entner–Doudoroff pathway of the archaeon Sulfolobus solfataricus

Published in:

FEBS Letters, 2005, v. 579, n. 30, p. 6865, doi. 10.1016/j.febslet.2005.11.028

By:

Lamble, Henry J.;
Theodossis, Alex;
Milburn, Christine C.;
Taylor, Garry L.;
Bull, Steven D.;
Hough, David W.;
Danson, Michael J.

Publication type:

Article

In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project.

Published in:

Environmental Health Perspectives, 2010, v. 118, n. 4, p. 485, doi. 10.1289/ehp.0901392

By:

Judson, Richard S.;
Houck, Keith A.;
Kavlock, Robert J.;
Knudsen, Thomas B.;
Martin, Matthew T.;
Mortensen, Holly M.;
Reif, David M.;
Rotroff, Daniel M.;
Shah, Imran;
Richard, Ann M.;
Dix, David J.

Publication type:

Article

The Impact of Non-Enzymatic Reactions and Enzyme Promiscuity on Cellular Metabolism during (Oxidative) Stress Conditions.

Published in:

Biomolecules (2218-273X), 2015, v. 5, n. 3, p. 2101, doi. 10.3390/biom5032101

By:

Piedrafita, Gabriel;
Keller, Markus A.;
Ralser, Markus

Publication type:

Article

The C orynebacterium glutamicum mycothiol peroxidase is a reactive oxygen species-scavenging enzyme that shows promiscuity in thiol redox control.

Published in:

Molecular Microbiology, 2015, v. 96, n. 6, p. 1176, doi. 10.1111/mmi.12998

By:

Pedre, Brandán;
Van Molle, Inge;
Villadangos, Almudena F.;
Wahni, Khadija;
Vertommen, Didier;
Turell, Lucía;
Erdogan, Huriye;
Mateos, Luis M.;
Messens, Joris

Publication type:

Article

Molecular annotation of ketol-acid reductoisomerases from S treptomyces reveals a novel amino acid biosynthesis interlock mediated by enzyme promiscuity.

Published in:

Microbial Biotechnology, 2015, v. 8, n. 2, p. 239, doi. 10.1111/1751-7915.12175

By:

Verdel-Aranda, Karina;
López-Cortina, Susana T.;
Hodgson, David A.;
Barona-Gómez, Francisco

Publication type:

Article

The chemical versatility of the β–α–β fold: Catalytic promiscuity and divergent evolution in the tautomerase superfamily.

Published in:

Cellular & Molecular Life Sciences, 2008, v. 65, n. 22, p. 3606, doi. 10.1007/s00018-008-8285-x

By:

Poelarends, G. J.;
Veetil, V. Puthan;
Whitman, C. P.

Publication type:

Article

Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5’-Phosphate Production in E. coli.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.pcbi.1004705

By:

Oberhardt, Matthew A.;
Zarecki, Raphy;
Reshef, Leah;
Xia, Fangfang;
Duran-Frigola, Miquel;
Schreiber, Rachel;
Henry, Christopher S.;
Ben-Tal, Nir;
Dwyer, Daniel J.;
Gophna, Uri;
Ruppin, Eytan

Publication type:

Article

Pyranose Dehydrogenase Ligand Promiscuity: A Generalized Approach to Simulate Monosaccharide Solvation, Binding, and Product Formation.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.pcbi.1003995

By:

Graf, Michael M. H.;
Zhixiong, Lin;
Bren, Urban;
Haltrich, Dietmar;
van Gunsteren, Wilfred F.;
Oostenbrink, Chris

Publication type:

Article

Diverse functional evolution of type II pyridoxal 5'-phosphate decarboxylases: Detection of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates.

Published in:

BMC Plant Biology, 2014, v. 14, n. 1, p. 1, doi. 10.1186/s12870-014-0247-x

By:

Torrens-Spence, Michael;
Guggenberg, Renee von;
Michael Lazear;
Haizhen Ding;
Jianyong Li

Publication type:

Article

Molecular dynamics simulations give insight into d-glucose dioxidation at C2 and C3 by Agaricus meleagris pyranose dehydrogenase.

Published in:

Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 4, p. 295, doi. 10.1007/s10822-013-9645-7

By:

Graf, Michael;
Bren, Urban;
Haltrich, Dietmar;
Oostenbrink, Chris

Publication type:

Article

Mapping catalytic promiscuity in the alkaline phosphatase superfamily.

Published in:

Pure & Applied Chemistry, 2009, v. 81, n. 4, p. 731, doi. 10.1351/PAC-CON-08-10-20

By:

Jonas, Stefanie;
Hollfelder, Florian

Publication type:

Article

Promiscuous Lipase-Catalyzed C-C Bond Formation Reactions Between 4 Nitrobenzaldehyde and 2-Cyclohexen-1-one in Biphasic Medium: Aldol and Morita-Baylis-Hillman Adduct Formations.

Published in:

Catalysis Letters, 2015, v. 145, n. 2, p. 527, doi. 10.1007/s10562-014-1429-8

By:

Kapoor, Manali;
Majumder, Abir;
Gupta, Munishwar

Publication type:

Article

Promiscuous activity of ( S, S)-butanediol dehydrogenase is responsible for glycerol production from 1,3-dihydroxyacetone in Corynebacterium glutamicum under oxygen-deprived conditions.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 3, p. 1427, doi. 10.1007/s00253-014-6170-0

By:

Jojima, Toru;
Igari, Takafumi;
Moteki, Yasuhiro;
Suda, Masako;
Yukawa, Hideaki;
Inui, Masayuki

Publication type:

Article

The Henry Reaction in [Bmim][PF<sub>6</sub>]-based Microemulsions Promoted by Acylase.

Published in:

Molecules, 2013, v. 18, n. 11, p. 13910, doi. 10.3390/molecules181113910

By:

Wen-Jian Xia;
Zong-Bo Xie;
Guo-Fang Jiang;
Zhang-Gao Le

Publication type:

Article

Discovery of novel geranylgeranyl reductases and characterization of their substrate promiscuity.

Published in:

Biotechnology for Biofuels, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13068-018-1342-2

By:

Meadows, Corey W.;
Garabedian, Brett M.;
Baidoo, Edward E. K.;
Benites, Veronica T.;
Rodrigues, Andria V.;
Lee, Taek Soon;
Mingardon, Florence;
Abourjeily, Raya;
Chanal, Angelique

Publication type:

Article

Evolution of Enzyme Kinetic Mechanisms.

Published in:

Journal of Molecular Evolution, 2015, v. 80, n. 5/6, p. 251, doi. 10.1007/s00239-015-9681-0

By:

Ulusu, Nuriye

Publication type:

Article

Evolution of Cyclic Amidohydrolases: A Highly Diversified Superfamily.

Published in:

Journal of Molecular Evolution, 2013, v. 77, n. 3, p. 70, doi. 10.1007/s00239-013-9580-1

By:

Barba, Matthieu;
Glansdorff, Nicolas;
Labedan, Bernard

Publication type:

Article

Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing.

Published in:

Nature Chemistry, 2014, v. 6, n. 1, p. 65, doi. 10.1038/nchem.1817

By:

Both, P.;
Green, A. P.;
Gray, C. J.;
Šardzík, R.;
Voglmeir, J.;
Fontana, C.;
Austeri, M.;
Rejzek, M.;
Richardson, D.;
Field, R. A.;
Widmalm, G.;
Flitsch, S. L.;
Eyers, C. E.

Publication type:

Article

Chemoenzymatic synthesis of differentially protected 3-deoxysugars.

Published in:

Nature Chemistry, 2010, v. 2, n. 2, p. 102, doi. 10.1038/nchem.504

By:

Gillingham, Dennis G.;
Stallforth, Pierre;
Adibekian, Alexander;
Seeberger, Peter H.;
Hilvert, Donald

Publication type:

Article

Insights into the evolution of enzyme substrate promiscuity after the discovery of (βα)<sub>8</sub> isomerase evolutionary intermediates from a diverse metagenome.

Published in:

BMC Evolutionary Biology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12862-015-0378-1

By:

Noda-García, Lianet;
Juárez-Vázquez, Ana L.;
Ávila-Arcos, María C.;
Verduzco-Castro, Ernesto A.;
Montero-Morán, Gabriela;
Gaytán, Paul;
Carrillo-Tripp, Mauricio;
Barona-Gómez, Francisco

Publication type:

Article

The ancestral activation promiscuity of ADPglucose pyrophosphorylases from oxygenic photosynthetic organisms.

Published in:

BMC Evolutionary Biology, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2148-13-51

By:

Kuhn, Misty L.;
Figueroa, Carlos M.;
Iglesias, Alberto A.;
Ballicora, Miguel A.

Publication type:

Article