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Prophylactic management of cerebral vasospasm with clazosentan in real clinical practice: a single-center retrospective cohort study.
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- Frontiers in Neurology, 2024, p. 1, doi. 10.3389/fneur.2024.1413632
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- Article
Single-cell RNA transcriptomic reveal the mechanism of MSC derived small extracellular vesicles against DKD fibrosis.
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- Journal of Nanobiotechnology, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12951-024-02613-2
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- Article
The Anti-Atherosclerotic Effects of Endothelin Receptor Antagonist, Bosentan, in Combination with Atorvastatin—An Experimental Study.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6614, doi. 10.3390/ijms25126614
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- Article
Hypertension and Heart Failure: From Pathophysiology to Treatment.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6661, doi. 10.3390/ijms25126661
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- Article
Graphene Far-Infrared Irradiation Can Effectively Relieve the Blood Pressure Level of Rat Untr-HT in Primary Hypertension.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6675, doi. 10.3390/ijms25126675
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- Article
Preliminary Mechanism of Glial Maturation Factor β on Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
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- Advanced Biology, 2024, v. 8, n. 6, p. 1, doi. 10.1002/adbi.202300623
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- Article
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ET<sub>A</sub> and ET<sub>B</sub> receptors in human cardiorenal tissue.
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- Bioscience Reports, 2024, v. 44, n. 6, p. 1, doi. 10.1042/BSR20240604
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- Article
Is endothelin targeting finally ready for prime time?
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- Clinical Science, 2024, v. 138, n. 11, p. 635, doi. 10.1042/CS20240607
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- Article
Mechanism of protective actions of sparsentan in the kidney: lessons from studies in models of chronic kidney disease.
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- Clinical Science, 2024, v. 138, n. 11, p. 645, doi. 10.1042/CS20240249
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- Article
Targeting the endothelium by combining endothelin-1 antagonism and SGLT-2 inhibition: better together?
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- Clinical Science, 2024, v. 138, n. 11, p. 687, doi. 10.1042/CS20240605
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- Article
Molecular Aspects of Cardiometabolic Diseases: From Etiopathogenesis to Potential Therapeutic Targets.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 5841, doi. 10.3390/ijms25115841
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- Article
Population pharmacokinetics of the dual endothelin receptor antagonist aprocitentan in subjects with or without essential or resistant hypertension.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2024, v. 51, n. 3, p. 243, doi. 10.1007/s10928-024-09902-1
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- Article
Mechanisms of cordycepin in the treatment of pulmonary arterial hypertension in rats based on metabonomics and transcriptomics.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-62163-3
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- Article
Role of Vasoactive Hormone-Induced Signal Transduction in Cardiac Hypertrophy and Heart Failure.
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- Cells (2073-4409), 2024, v. 13, n. 10, p. 856, doi. 10.3390/cells13100856
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- Article
BMPR2 Loss Activates AKT by Disrupting DLL4/NOTCH1 and PPARγ Signaling in Pulmonary Arterial Hypertension.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5403, doi. 10.3390/ijms25105403
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- Article
Integrated metabolomics analysis reveals mechanistic insights into variability in blood pressure response to thiazide diuretics and beta blockers.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 5, p. 1, doi. 10.1111/cts.13816
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- Article
Long-term safety and tolerability of ambrisentan treatment for pediatric patients with pulmonary arterial hypertension: An open-label extension study.
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- European Journal of Pediatrics, 2024, v. 183, n. 5, p. 2141, doi. 10.1007/s00431-024-05446-1
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- Article
Enhancing High School Students' Future Thinking Skills through Interactive Digital Platforms for Teaching Energy Issues.
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- International Journal of Interactive Mobile Technologies, 2024, v. 18, n. 9, p. 4, doi. 10.3991/ijim.v18i09.48879
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- Article
Non-Classical Effects of FGF23: Molecular and Clinical Features.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 9, p. 4875, doi. 10.3390/ijms25094875
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- Article
Correction to: Histamine H2‑receptor antagonism improves conduit artery endothelial function and reduces plasma aldosterone level without lowering arterial blood pressure in angiotensin II–hypertensive mice.
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- 2024
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- Correction Notice
Switching from Beraprost to Selexipag in the Treatment of Pulmonary Arterial Hypertension: Insights from a Phase IV Study of the Japanese Registry (The EXCEL Study: EXChange from bEraprost to seLexipag Study).
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- Pharmaceuticals (14248247), 2024, v. 17, n. 5, p. 555, doi. 10.3390/ph17050555
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- Article
The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition.
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- Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01603-z
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- Article
The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1369489
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- Article
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1332394
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- Article
Maximizing the Therapeutic Effect of Endothelin Receptor Antagonists in Pulmonary Fibrosis: A Paradigm for Treating the Disease.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4184, doi. 10.3390/ijms25084184
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- Article
Dysregulated VEGF/VEGFR-2 Signaling and Plexogenic Lesions in the Embryonic Lungs of Chickens Predisposed to Pulmonary Arterial Hypertension.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4489, doi. 10.3390/ijms25084489
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- Article
The Pathophysiological, Genetic, and Hormonal Changes in Preeclampsia: A Systematic Review of the Molecular Mechanisms.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4532, doi. 10.3390/ijms25084532
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- Article
Identification of potential biomarkers for idiopathic pulmonary arterial hypertension using single-cell and bulk RNA sequencing analysis.
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- Frontiers in Genetics, 2024, p. 1, doi. 10.3389/fgene.2024.1328234
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- Article
Endothelin receptor antagonists in diabetic and non-diabetic chronic kidney disease.
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- Clinical Kidney Journal, 2024, v. 17, n. 4, p. 1, doi. 10.1093/ckj/sfae072
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- Article
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3969, doi. 10.3390/ijms25073969
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- Article
Distribution of cionin, a cholecystokinin/gastrin family peptide, and its receptor in the central nervous system of Ciona intestinalis type A.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55908-7
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- Article
Comparison of efficacy between clazosentan and fasudil hydrochloride-based management of vasospasm after subarachnoid hemorrhage focusing on older and WFNS grade V patients: a single-center experience in Japan.
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- Neurosurgical Review, 2024, v. 47, n. 1, p. 1, doi. 10.1007/s10143-024-02345-9
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- Article
The Impact of Immunogenicity on the Pharmacokinetics, Efficacy, and Safety of Sotatercept in a Phase III Study of Pulmonary Arterial Hypertension.
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- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 3, p. 478, doi. 10.1002/cpt.3116
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- Article
Intravenous Ganaxolone: Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability in Healthy Adults.
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- Clinical Pharmacology in Drug Development, 2024, v. 13, n. 3, p. 248, doi. 10.1002/cpdd.1365
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- Article
Tumor biomarkers in evaluating the severity and prognosis of idiopathic pulmonary arterial hypertension: A comprehensive analysis.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13751
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- Article
Safety, pharmacokinetics, and pharmacodynamics in healthy Chinese volunteers treated with SC0062, a highly selective endothelin‐A receptor antagonist.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13750
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- Article
Safety of Dual Orexin Receptor Antagonist Daridorexant: A Disproportionality Analysis of Publicly Available FAERS Data.
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- Pharmaceuticals (14248247), 2024, v. 17, n. 3, p. 342, doi. 10.3390/ph17030342
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- Article
Identification of EDNRA as the Key Biomarker for Hypercholesterolemia and Colorectal Cancer.
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- Tohoku Journal of Experimental Medicine, 2024, v. 262, n. 3, p. 181, doi. 10.1620/tjem.2023.J101
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- Article
Renal Expression and Localization of the Receptor for (Pro)renin and Its Ligands in Rodent Models of Diabetes, Metabolic Syndrome, and Age-Dependent Focal and Segmental Glomerulosclerosis.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 4, p. 2217, doi. 10.3390/ijms25042217
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- Article
Autoantibodies Targeting G-Protein-Coupled Receptors: Pathogenetic, Clinical and Therapeutic Implications in Systemic Sclerosis.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 4, p. 2299, doi. 10.3390/ijms25042299
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- Article
The Role of the Endocrine System in the Regulation of Acid–Base Balance by the Kidney and the Progression of Chronic Kidney Disease.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 4, p. 2420, doi. 10.3390/ijms25042420
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- Article
Time Is Running Out in Pulmonary Arterial Hypertension: The Epigenetic Clock Is Clicking.
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- American Journal of Respiratory Cell & Molecular Biology, 2024, v. 70, n. 2, p. 140, doi. 10.1165/rcmb.2023-0335le
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- Article
The Activation of GABA A R Alleviated Cerebral Ischemic Injury via the Suppression of Oxidative Stress, Autophagy, and Apoptosis Pathways.
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- Antioxidants, 2024, v. 13, n. 2, p. 194, doi. 10.3390/antiox13020194
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- Article
Diabetes mellitus, glycemic traits, SGLT2 inhibition, and risk of pulmonary arterial hypertension: A Mendelian randomization study.
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- BioScience Trends, 2024, v. 18, n. 1, p. 94, doi. 10.5582/bst.2024.01006
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- Article
Anti-collagenase, Anti-elastase, Anti-urease, and Anti-cancer Potentials of Isokaempferide as Natural Compound: In vitro and in silico Study.
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- Journal of Oleo Science, 2024, v. 73, n. 2, p. 187, doi. 10.5650/jos.ess23176
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- Article
Melatonin as an anti-stress signal: effects on an acute stress model and direct actions on interrenal tissue in goldfish.
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- Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2023.1291153
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- Article
Special Issue IJMS—Molecular Mechanisms of Diabetic Kidney Disease.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 790, doi. 10.3390/ijms25020790
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- Article
Interplay of Angiotensin Peptides, Vasopressin, and Insulin in the Heart: Experimental and Clinical Evidence of Altered Interactions in Obesity and Diabetes Mellitus.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1310, doi. 10.3390/ijms25021310
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- Article
Liver injury due to endothelin receptor antagonists: a real-world study based on post-marketing drug monitoring data.
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- Therapeutic Advances in Respiratory Disease, 2024, p. 1, doi. 10.1177/17534666231223606
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- Article
Evaluation of NTP42, a novel thromboxane receptor antagonist, in a first-in-human phase I clinical trial.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1296188
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- Article