Works about ECULIZUMAB

Results: 803

Factor B as a therapeutic target for the treatment of complement-mediated diseases.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1537974
By:
- Kavanagh, David;
- Barratt, Jonathan;
- Schubart, Anna;
- Webb, Nicholas J. A.;
- Meier, Matthias;
- Fakhouri, Fadi
Publication type:
Article
Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2022.1039765
By:
- Hurler, Lisa;
- Toonen, Erik J. M.;
- Kajdácsi, Erika;
- van Bree, Bregje;
- Brandwijk, Ricardo J. M. G. E.;
- de Bruin, Wieke;
- Lyons, Paul A.;
- Bergamaschi, Laura;
- Sinkovits, György;
- Cervenak, László;
- Würzner, Reinhard;
- Prohászka, Zoltán;
- Baker, Stephen;
- Bradley, John R.;
- Chinnery, Patrick F.;
- Cooper, Daniel J.;
- Dougan, Gordon;
- Goodfellow, Ian G.;
- Gupta, Ravindra K.;
- Kingston, Nathalie
Publication type:
Article
Safety and effectiveness of eculizumab for pediatric patients with atypical hemolytic-uremic syndrome in Japan: interim analysis of post-marketing surveillance.
Published in:
Clinical & Experimental Nephrology, 2019, v. 23, n. 1, p. 112, doi. 10.1007/s10157-018-1610-2
By:
- Ito, Shuichi;
- Hidaka, Yoshihiko;
- Inoue, Norimitsu;
- Kaname, Shinya;
- Kato, Hideki;
- Matsumoto, Masanori;
- Miyakawa, Yoshitaka;
- Mizuno, Masashi;
- Okada, Hirokazu;
- Shimono, Akihiko;
- Matsuda, Takahisa;
- Maruyama, Shoichi;
- Fujimura, Yoshihiro;
- Nangaku, Masaomi;
- Kagami, Shoji
Publication type:
Article
Safety and effectiveness of eculizumab for adult patients with atypical hemolytic-uremic syndrome in Japan: interim analysis of post-marketing surveillance.
Published in:
Clinical & Experimental Nephrology, 2019, v. 23, n. 1, p. 65, doi. 10.1007/s10157-018-1609-8
By:
- Kato, Hideki;
- Miyakawa, Yoshitaka;
- Hidaka, Yoshihiko;
- Inoue, Norimitsu;
- Ito, Shuichi;
- Kagami, Shoji;
- Kaname, Shinya;
- Matsumoto, Masanori;
- Mizuno, Masashi;
- Matsuda, Takahisa;
- Shimono, Akihiko;
- Maruyama, Shoichi;
- Fujimura, Yoshihiro;
- Nangaku, Masaomi;
- Okada, Hirokazu
Publication type:
Article
Efficacy and safety of eculizumab in childhood atypical hemolytic uremic syndrome in Japan.
Published in:
Clinical & Experimental Nephrology, 2016, v. 20, n. 2, p. 265, doi. 10.1007/s10157-015-1142-y
By:
- Ito, Naoko;
- Hataya, Hiroshi;
- Saida, Ken;
- Amano, Yoshiro;
- Hidaka, Yoshihiko;
- Motoyoshi, Yaeko;
- Ohta, Toshiyuki;
- Yoshida, Yasuhiro;
- Terano, Chikako;
- Iwasa, Tadashi;
- Kubota, Wataru;
- Takada, Hidetoshi;
- Hara, Toshiro;
- Fujimura, Yoshihiro;
- Ito, Shuichi
Publication type:
Article
Effect of dipeptidyl peptidase‐4 inhibitors on complement activation.
Published in:
Diabetes/Metabolism Research & Reviews, 2021, v. 37, n. 3, p. 1, doi. 10.1002/dmrr.3385
By:
- Hoffmann‐Petersen, Ingeborg T.;
- Holt, Charlotte B.;
- Jensen, Lisbeth;
- Hage, Camilla;
- Mellbin, Linda G.;
- Thiel, Steffen;
- Hansen, Troels K.;
- Østergaard, Jakob A.
Publication type:
Article
Comparative Study of the Stability of Eculizumab Biosimilar and the Original Drug under Extreme pH, Oxidative Stress, and UV Irradiation Conditions.
Published in:
Pharmaceutical Chemistry Journal, 2021, v. 55, n. 7, p. 732, doi. 10.1007/s11094-021-02485-y
By:
- Zybin, D. I.;
- Zhuchenko, M. A.;
- Rassulin, Yu. Yu.;
- Askretkov, A. D.;
- Prostyakova, A. I.;
- Ishchenko, A. A.;
- Orlova, N. V.;
- Seregin, Yu. A.;
- Kapustin, D. V.
Publication type:
Article
High Risk for Invasive Meningococcal Disease Among Patients Receiving Eculizumab (Soliris) Despite Receipt of Meningococcal Vaccine.
Published in:
2017
By:
- McNamara, Lucy A.;
- Topaz, Nadav;
- Xin Wang;
- Hariri, Susan;
- Fox, LeAnne;
- MacNeil, Jessica R.;
- Wang, Xin
Publication type:
journal article
Eculizumab in refractory myasthenia gravis: a real-world single-center experience.
Published in:
Neurological Sciences, 2025, v. 46, n. 2, p. 951, doi. 10.1007/s10072-024-07861-6
By:
- Ricciardi, Dario;
- Erra, Carmen;
- Tuccillo, Francesco;
- De Martino, Bernardo Maria;
- Fasolino, Alessandra;
- Habetswallner, Francesco
Publication type:
Article
Therapeutic challenges and unmet needs in the management of myasthenia gravis: an Italian expert opinion.
Published in:
Neurological Sciences, 2024, v. 45, n. 12, p. 5671, doi. 10.1007/s10072-024-07577-7
By:
- Mantegazza, Renato;
- Saccà, Francesco;
- Antonini, Giovanni;
- Bonifati, Domenico Marco;
- Evoli, Amelia;
- Habetswallner, Francesco;
- Liguori, Rocco;
- Pegoraro, Elena;
- Rodolico, Carmelo;
- Schenone, Angelo;
- Sgarzi, Manlio;
- Pappagallo, Giovanni
Publication type:
Article
Eculizumab for myasthenic exacerbation during treatment with immune-checkpoint inhibitors.
Published in:
Neurological Sciences, 2024, v. 45, n. 3, p. 1243, doi. 10.1007/s10072-023-07190-0
By:
- Fionda, Laura;
- Rossini, Elena;
- Lauletta, Antonio;
- Leonardi, Luca;
- Tufano, Laura;
- Costanzo, Rocco;
- Marchetti, Paolo;
- Salvetti, Marco;
- Garibaldi, Matteo;
- Morino, Stefania;
- Antonini, Giovanni
Publication type:
Article
Eculizumab for a catastrophic relapse in NMOSD: case report.
Published in:
Neurological Sciences, 2024, v. 45, n. 1, p. 249, doi. 10.1007/s10072-023-06971-x
By:
- Gorriz, David;
- Pérez-Miralles, Francisco Carlos;
- Quintanilla-Bordás, Carlos;
- Alcalá, Carmen;
- Frasquet, Marina;
- Casanova, Bonaventura
Publication type:
Article
Eculizumab as a promising rescue therapy for acute exacerbations of myasthenia gravis.
Published in:
Neurological Sciences, 2023, v. 44, n. 12, p. 4573, doi. 10.1007/s10072-023-06993-5
By:
- Kim, Sohyeon;
- Lee, Jae-Joon;
- Seok, Hung Youl
Publication type:
Article
Starting eculizumab as rescue therapy in refractory myasthenic crisis.
Published in:
Neurological Sciences, 2023, v. 44, n. 10, p. 3707, doi. 10.1007/s10072-023-06900-y
By:
- Vinciguerra, Claudia;
- Bevilacqua, Liliana;
- Toriello, Antonella;
- Iovino, Aniello;
- Piscosquito, Giuseppe;
- Calicchio, Giuseppe;
- Barone, Paolo
Publication type:
Article
A safe change from eculizumab to satralizumab in a patient with neuromyelitis optica spectrum disorder.
Published in:
Neurological Sciences, 2023, v. 44, n. 3, p. 1097, doi. 10.1007/s10072-022-06495-w
By:
- Funakoshi, Kei;
- Suzuki, Keisuke
Publication type:
Article
Generalized myasthenia gravis patients infected with COVID-19 should continue eculizumab.
Published in:
Neurological Sciences, 2022, v. 43, n. 7, p. 4081, doi. 10.1007/s10072-022-05922-2
By:
- Mimori, Masahiro;
- Komatsu, Teppei;
- Maku, Takahiro;
- Mitsumura, Hidetaka;
- Iguchi, Yasuyuki
Publication type:
Article
Benefit and danger from immunotherapy in myasthenia gravis.
Published in:
Neurological Sciences, 2021, v. 42, n. 4, p. 1367, doi. 10.1007/s10072-021-05077-6
By:
- Rodolico, Carmelo;
- Nicocia, Giulia;
- Damato, Valentina;
- Antonini, Giovanni;
- Liguori, Rocco;
- Evoli, Amelia
Publication type:
Article
Correction to: Eculizumab improves fatigue in refractory generalized myasthenia gravis.
Published in:
2019
By:
- Andersen, Henning;
- Mantegazza, Renato;
- Wang, Jing Jing;
- O'Brien, Fanny;
- Patra, Kaushik;
- Howard, James F.;
- Howard, James F Jr;
- REGAIN Study Group
Publication type:
corrected article
Eculizumab improves fatigue in refractory generalized myasthenia gravis.
Published in:
2019
By:
- Andersen, Henning;
- Mantegazza, Renato;
- Wang, Jing Jing;
- O'Brien, Fanny;
- Patra, Kaushik;
- Howard, James F.;
- Howard, James F Jr;
- REGAIN Study Group
Publication type:
journal article
JAK/STAT inhibition augments soleus muscle function in a rat model of critical illness myopathy via regulation of complement C3/3R.
Published in:
Journal of Physiology, 2021, v. 599, n. 11, p. 2869, doi. 10.1113/JP281220
By:
- Addinsall, Alex B.;
- Cacciani, Nicola;
- Akkad, Hazem;
- Salah, Heba;
- Tchkonia, Tamara;
- Kirkland, James L.;
- Larsson, Lars
Publication type:
Article
Xenotransplantation literature update, March-April 2016.
Published in:
Xenotransplantation, 2016, v. 23, n. 3, p. 249, doi. 10.1111/xen.12241
By:
- Burlak, Christopher
Publication type:
Article
Safety and Efficacy of Eculizumab Therapy in Multiple Sclerosis: A Case Series.
Published in:
Brain Sciences (2076-3425), 2021, v. 11, n. 10, p. 1341, doi. 10.3390/brainsci11101341
By:
- Allinovi, Marco;
- Bellinvia, Angelo;
- Pesce, Francesco;
- Milan Manani, Sabrina;
- Razzolini, Lorenzo;
- Brezzi, Brigida;
- Protopapa, Paolo;
- Mantero, Vittorio;
- Caroti, Leonardo;
- Cirami, Calogero Lino;
- Amato, Maria Pia;
- Del Vecchio, Lucia
Publication type:
Article
Management of haemophilia A with inhibitors: A regional cross‐talk.
Published in:
Haemophilia, 2022, v. 28, n. 6, p. 950, doi. 10.1111/hae.14638
By:
- Peyvandi, Flora;
- Kavakli, Kaan;
- El‐Beshlawy, Amal;
- Rangarajan, Savita
Publication type:
Article
Plasma levels of mannan-binding lectin-associated serine proteases are increased in type 1 diabetes patients with insulin resistance.
Published in:
Clinical & Experimental Immunology, 2024, v. 215, n. 1, p. 58, doi. 10.1093/cei/uxad113
By:
- Kietsiriroje, Noppadol;
- Scott, Georgia E;
- Ajjan, Ramzi A;
- Brôz, Jan;
- Schroeder, Verena;
- Campbell, Matthew D
Publication type:
Article
Complement terminal pathway inhibition reduces peritoneal injuries in a rat peritonitis model.
Published in:
Clinical & Experimental Immunology, 2023, v. 214, n. 2, p. 209, doi. 10.1093/cei/uxad088
By:
- Kamegai, Naoki;
- Kim, Hangsoo;
- Suzuki, Yasuhiro;
- Fukui, Sosuke;
- Kojima, Hiroshi;
- Maruyama, Shoichi;
- Morgan, B Paul;
- Zelek, Wioleta Milena;
- Mizuno, Masashi
Publication type:
Article
Differentiating between activation via the lectin or the classical complement pathway in patients with systemic lupus erythematosus.
Published in:
Clinical & Experimental Immunology, 2023, v. 214, n. 1, p. 18, doi. 10.1093/cei/uxad070
By:
- Larsen, Mads Lamm;
- Troldborg, Anne;
- Toonen, Erik J M;
- Hurler, Lisa;
- Prohaszka, Zoltan;
- Cervenak, László;
- Gudmann Hansen, Annette;
- Thiel, Steffen
Publication type:
Article
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence.
Published in:
Clinical & Experimental Immunology, 2023, v. 213, n. 2, p. 252, doi. 10.1093/cei/uxad055
By:
- Elhadad, Sonia;
- Redmond, David;
- Huang, Jenny;
- Tan, Adrian;
- Laurence, Jeffrey
Publication type:
Article
miR-132-3p regulates antibody-mediated complement-dependent cytotoxicity in colon cancer cells by directly targeting CD55.
Published in:
Clinical & Experimental Immunology, 2023, v. 211, n. 1, p. 57, doi. 10.1093/cei/uxac120
By:
- Fan, Yu;
- Liao, Juan;
- Wang, Yu;
- Wang, Zhu;
- Zheng, Hong;
- Wang, Yanping
Publication type:
Article
Elevated expression of TAM receptor tyrosine kinase in synovial fluid and synovial tissue of rheumatoid arthritis.
Published in:
Clinical & Experimental Immunology, 2022, v. 209, n. 3, p. 270, doi. 10.1093/cei/uxac071
By:
- Zheng, Li;
- Xu, Liling;
- Hu, Fanlei;
- Xue, Jimeng;
- Bai, Mingxin;
- Yao, Ranran;
- Zhu, Huaqun;
- Zhong, Hua;
- Su, Yin
Publication type:
Article
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti‐MASP2 antibody narsoplimab.
Published in:
Clinical & Experimental Immunology, 2021, v. 203, n. 1, p. 96, doi. 10.1111/cei.13497
By:
- Elhadad, S.;
- Chapin, J.;
- Copertino, D.;
- Van Besien, K.;
- Ahamed, J.;
- Laurence, J.
Publication type:
Article
Carbamylation reduces the capacity of IgG for hexamerization and complement activation.
Published in:
Clinical & Experimental Immunology, 2020, v. 200, n. 1, p. 1, doi. 10.1111/cei.13411
By:
- Lubbers, R.;
- Oostindie, S. C.;
- Dijkstra, D. J.;
- Parren, P. W. H. I.;
- Verheul, M. K.;
- Abendstein, L.;
- Sharp, T. H.;
- Ru, A.;
- Janssen, G. M. C.;
- Veelen, P. A.;
- den Bremer, E. T. J.;
- Bleijlevens, B.;
- Kreuk, B.‐J.;
- Beurskens, F. J.;
- Trouw, L. A.
Publication type:
Article
Multi‐component meningococcal serogroup B (MenB)‐4C vaccine induces effective opsonophagocytic killing in children with a complement deficiency.
Published in:
Clinical & Experimental Immunology, 2019, v. 198, n. 3, p. 381, doi. 10.1111/cei.13368
By:
- van den Broek, B.;
- Els, C. A. C. M.;
- Kuipers, B.;
- Aerde, K.;
- Henriet, S. S.;
- Groot, R.;
- Jonge, M. I.;
- Langereis, J. D.;
- Flier, M.
Publication type:
Article
Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli‐induced coagulation accompanied by Toll‐like receptor 4.
Published in:
Clinical & Experimental Immunology, 2019, v. 196, n. 1, p. 97, doi. 10.1111/cei.13240
By:
- Landsem, A.;
- Fure, H.;
- Krey Ludviksen, J.;
- Christiansen, D.;
- Lau, C.;
- Mathisen, M.;
- Bergseth, G.;
- Nymo, S.;
- Lappegård, K. T.;
- Woodruff, T. M.;
- Espevik, T.;
- Mollnes, T. E.;
- Brekke, O.‐L.
Publication type:
Article
Monitoring of complement activation biomarkers and eculizumab in complement-mediated renal disorders.
Published in:
Clinical & Experimental Immunology, 2017, v. 187, n. 2, p. 304, doi. 10.1111/cei.12890
By:
- Wehling, C.;
- Amon, O.;
- Bommer, M.;
- Hoppe, B.;
- Kentouche, K.;
- Schalk, G.;
- Weimer, R.;
- Wiesener, M.;
- Hohenstein, B.;
- Tönshoff, B.;
- Büscher, R.;
- Fehrenbach, H.;
- Gök, Ö.‐N.;
- Kirschfink, M.
Publication type:
Article
The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load.
Published in:
Clinical & Experimental Immunology, 2015, v. 181, n. 3, p. 457, doi. 10.1111/cei.12645
By:
- Egge, Kjetil H.;
- Barratt‐Due, Andreas;
- Nymo, Stig;
- Lindstad, Julie K.;
- Pharo, Anne;
- Lau, Corinna;
- Espevik, Terje;
- Thorgersen, Ebbe B.;
- Mollnes, Tom E.
Publication type:
Article
Practical issues in using eculizumab for children with atypical haemolytic uraemic syndrome in the acute phase: A review of four patients.
Published in:
Nephrology, 2018, v. 23, n. 6, p. 539, doi. 10.1111/nep.13054
By:
- Terano, Chikako;
- Ishikura, Kenji;
- Hamada, Riku;
- Yoshida, Yasuhiro;
- Kubota, Wataru;
- Okuda, Yusuke;
- Shinozuka, Shunsuke;
- Harada, Ryoko;
- Iyoda, Sunao;
- Fujimura, Yoshihiro;
- Hamasaki, Yuko;
- Hataya, Hiroshi;
- Honda, Masataka
Publication type:
Article
Subclinical atypical haemolytic uremic syndrome relapse following discontinuation of eculizumab.
Published in:
Nephrology, 2017, v. 22, p. 4, doi. 10.1111/nep.12931
By:
- Choo, Shi Zhou;
- Brown, Fiona
Publication type:
Article
Long-term remission with eculizumab in atypical haemolytic uraemic syndrome.
Published in:
Nephrology, 2017, v. 22, p. 7, doi. 10.1111/nep.12932
By:
- Carter, Simon;
- Hewitt, Ian;
- Kausman, Joshua
Publication type:
Article
Suspected atypical haemolytic uraemic syndrome in two post-partum patients with foetal-death in utero responding to eculizumab.
Published in:
Nephrology, 2017, v. 22, p. 18, doi. 10.1111/nep.12935
By:
- Chua, Justin;
- Paizis, Kathy;
- He, Simon Z.;
- Mount, Peter
Publication type:
Article
De novo thrombotic microangiopathy following simultaneous pancreas and kidney transplantation managed with eculizumab.
Published in:
Nephrology, 2017, v. 22, p. 23, doi. 10.1111/nep.12936
By:
- Shochet, Lani;
- Kanellis, John;
- Simpson, Ian;
- Ta, Joseph;
- Mulley, William
Publication type:
Article
Absence of thrombocytopaenia and/or microangiopathic haemolytic anaemia does not reliably exclude recurrence of atypical haemolytic uraemic syndrome after kidney transplantation.
Published in:
Nephrology, 2017, v. 22, p. 28, doi. 10.1111/nep.12937
By:
- Krishnan, Anoushka R;
- Siva, Brian;
- Chakera, Aron;
- Wong, Germaine;
- Wong, Daniel;
- Lim, Wai H
Publication type:
Article
Life-threatening pregnancy-associated atypical haemolytic uraemic syndrome and its response to eculizumab.
Published in:
Nephrology, 2017, v. 22, p. 32, doi. 10.1111/nep.12938
By:
- Gately, Ryan;
- San, Aye;
- Kurtkoti, Jagadeesh;
- Parnham, Alan
Publication type:
Article
Issue Information.
Published in:
Nephrology, 2017, v. 22, p. 1, doi. 10.1111/nep.12962
Publication type:
Article
Two cases of kidney transplantation-associated thrombotic microangiopathy successfully treated with eculizumab.
Published in:
Nephrology, 2016, v. 21, p. 35, doi. 10.1111/nep.12768
By:
- Ikeda, Takashi;
- Okumi, Masayoshi;
- Unagami, Kohei;
- Kanzawa, Taichi;
- Sawada, Anri;
- Kawanishi, Kunio;
- Omoto, Kazuya;
- Ishida, Hideki;
- Tanabe, Kazunari
Publication type:
Article
Prevention and treatment of atypical haemolytic uremic syndrome after kidney transplantation.
Published in:
Nephrology, 2016, v. 21, p. 9, doi. 10.1111/nep.12776
By:
- Okumi, Masayoshi;
- Tanabe, Kazunari
Publication type:
Article
Irreversible severe kidney injury and anuria in a 3-month-old girl with atypical haemolytic uraemic syndrome under administration of eculizumab.
Published in:
Nephrology, 2016, v. 21, n. 3, p. 261, doi. 10.1111/nep.12582
By:
- Okuda, Yusuke;
- Ishikura, Kenji;
- Terano, Chikako;
- Harada, Ryoko;
- Hamada, Riku;
- Hataya, Hiroshi;
- Ogata, Kentaro;
- Honda, Masataka
Publication type:
Article
Recovery from life-threatening transplantation-associated thrombotic microangiopathy using eculizumab in a patient with very severe aplastic anemia.
Published in:
Bone Marrow Transplantation, 2014, v. 49, n. 8, p. 1116, doi. 10.1038/bmt.2014.97
By:
- Okano, M;
- Sakata, N;
- Ueda, S;
- Takemura, T
Publication type:
Article
Improved Renal Recovery with Eculizumab Therapy among Children with High Prevalence of Mutation-Associated Atypical Hemolytic Uremic Syndrome: A Retrospective Cohort Study.
Published in:
Kidney & Blood Pressure Research, 2020, v. 45, n. 6, p. 939, doi. 10.1159/000510612
By:
- Bamhraz, Abdulaziz A.;
- Rahim, Khawla A.;
- Faqeehi, Hassan Y.;
- Alanazi, Abdulkarim
Publication type:
Article
Economic Impact of Early-in-Hospital Diagnosis and Initiation of Eculizumab in Atypical Haemolytic Uraemic Syndrome.
Published in:
2020
By:
- Ryan, Michael;
- Donato, Bonnie M. K.;
- Irish, William;
- Gasteyger, Christoph;
- L'Italien, Gilbert;
- Laurence, Jeffrey
Publication type:
journal article
Relapse of Atypical Hemolytic Uremic Syndrome During Pregnancy in a Patient on Eculizumab Maintenance Treatment: A Case Report.
Published in:
American Journal of Case Reports, 2019, v. 20, p. 1460, doi. 10.12659/AJCR.916994
By:
- Fontana, Francesco;
- Alfano, Geatano;
- Bardhushi, Ermelinda;
- Ligabue, Giulia;
- Giovanella, Silvia;
- Neri, Isabella;
- Cappelli, Gianni
Publication type:
Article